thiazoles has been researched along with Allodynia in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (12.50) | 18.2507 |
| 2000's | 9 (22.50) | 29.6817 |
| 2010's | 22 (55.00) | 24.3611 |
| 2020's | 4 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Ding, H; Lin, Z; Liu, B; Xiao, H; Yang, F; Zhan, H; Zhou, X | 1 |
| Ann, J; Blumberg, PM; Choi, K; Esch, TE; Ha, HJ; Hwang, SW; Kim, H; Kim, HS; Kim, M; Kim, YH; Lee, J; Pearce, LV; Thorat, SA; Turcios, NA | 1 |
| Hara, K; Haranishi, Y; Terada, T | 1 |
| Cao, N; Chen, Q; Deng, S; Gao, R; Kong, L; Li, L; Ma, K; Si, J; Tan, C; Tang, X; Wang, Y; Xu, Z; Zhang, J; Zhang, L; Zhang, M | 1 |
| Akasaka, R; Furukawa, A; Honda, K; Iwata, K; Kondo, M; Otsuki, K; Shimizu, K; Shinoda, M; Yonemoto, H | 1 |
| Britti, D; Crupi, R; Cuzzocrea, S; Di Paola, R; Evangelista, M; Fusco, R; Gugliandolo, E; Impellizzeri, D; Morittu, VM; Schievano, C | 1 |
| Bali, KK; Kuner, R | 1 |
| García, G; Martínez-Rojas, VA; Murbartián, J; Oviedo, N | 1 |
| De Koninck, Y; Gauthier, C; Lee, KY; Lorenzo, LE; Mapplebeck, JCS; Muley, MM; Prescott, SA; Salter, MW | 1 |
| Guillot, M; Heit, M; Martel-Pelletier, J; Moreau, M; Pelletier, JP; Troncy, E | 1 |
| Gao, M; Maixner, DW; Weng, HR | 1 |
| Asada, T; Hagiwara, M; Kawamoto, D; Kii, I; Kurihara, T; Miyata, A; Sakurai, E; Tanabe, T; Toyomoto, M; Yoshimura, M | 1 |
| Caplen, G; Hothersall, B; Murrell, JC; Nicol, CJ; Parker, RM; Waterman-Pearson, AE; Weeks, CA | 1 |
| Cardenas, R; Fernandez, AC; Guevara, C; Suarez-Roca, H | 1 |
| Boitano, S; Burgos-Vega, CC; Dussor, G; Hassler, SN; Price, TJ; Quinn, TL; Sorge, RE; Tillu, DV; Vagner, J | 1 |
| Castonguay, A; Chen, Z; Cottet, M; De Koninck, Y; Doyle, T; Egan, TM; Ford, A; Jacobson, KA; Little, JW; Salvemini, D; Symons-Liguori, AM; Tosh, DK; Vanderah, TW | 1 |
| Abdelazeem, AH; Maghrabi, IA; Salama, SA | 1 |
| Diniz, MS; Souza, VL; Steagall, PV; Teixeira, LR; Teixeira-Neto, FJ; Thomazini, CM; Zanuzzo, FS | 1 |
| Bernardes, CP; Cintra, AC; de Oliveira, F; Faccioli, LH; Mamede, CC; Menaldo, DL; Sampaio, SV; Stanziola, L; Zoccal, KF | 1 |
| Allegretti, M; Alves-Filho, JC; Aramini, A; Bianchini, G; Brandolini, L; Cunha, FQ; Cunha, TM; Lopes, AH; Silva, RL; Teixeira, MM; Verri, WA; Zaperlon, AC | 1 |
| Bi, RY; Ding, Y; Gan, YH | 1 |
| Andoh, T; Kuraishi, Y; Mizoguchi, S; Yakura, T | 1 |
| Ao, H; Bhattacharya, A; Branstetter, BJ; Chaplan, SR; Guy Breitenbucher, J; Hack, MD; Kansagara, M; Lebsack, AD; Luo, L; Maher, MP; Nasser, N; Peterson, ML; Rizzolio, M; Rynberg, R; Scott, BP; Wickenden, AD; Xiao, W | 1 |
| Dolezal, T; Janovský, M; Krsiak, M; Procháizková, M; Slíva, J | 1 |
| Ao, H; Bhattacharya, A; Branstetter, BJ; Breitenbucher, JG; Chaplan, SR; Eckert, WA; Fitzgerald, A; Freedman, J; Kansagara, M; Lebsack, AD; Li, DH; Liu, J; Liu, Y; Maher, MP; Rech, JC; Rizzolio, M; Scott, B; Sepassi, K; Swanson, N; Wickenden, AD; Wu, NT | 1 |
| Aono, H; Hata, T; Narita, M; Niwa, M; Sasano, M; Suzuki, T; Tsuji, F; Tsukahara-Ohsumi, Y | 1 |
| Cidral-Filho, FJ; Martins, DF; Mazzardo-Martins, L; Santos, AR; Stramosk, J | 1 |
| Atweh, SF; Bach, JF; Dardenne, M; Jabbur, SJ; Saadé, NE; Safieth-Garabedian, B | 1 |
| Decker, MW; Gauvin, DM; Honore, P; Lynch, JJ; Mikusa, JP; Wade, CL; Wilson, SG; Wismer, CT; Zhu, CZ | 1 |
| Shah, S; Tear, S | 1 |
| Dudhgaonkar, SP; Kumar, D; Naik, AK; Raviprakash, V; Tandan, SK | 1 |
| Devissaguet, M; Ferreira, SH; Lesieur, D; Lorenzetti, BB; Tsouderos, Y | 1 |
| Laird, JM; Lopez-Garcia, JA | 1 |
| Bornemeier, DA; Chan, K; Connor, DT; Doubleday, R; Dyer, RD; Gilbertsen, RB; Guglietta, A; Roth, BD; Schrier, DJ; Sercel, AD; Song, Y; Sorenson, RJ; Unangst, PC | 1 |
| Atweh, SF; Jabbur, SJ; Kanaan, SA; Lawand, HF; Saadé, NE; Safieh-Garabedian, B | 1 |
| Hu, D; Syriatowicz, JP; Tracey, DJ; Walker, JS | 1 |
| Atweh, SF; Dardenne, M; Jabbur, SJ; Kanaan, SA; Saadé, NE; Safieh-Garabedian, B | 1 |
| Carter, AJ; Cervero, F; Grauert, M; Laird, JM | 1 |
| Caignard, DH; Chavatte, P; Espiard, JG; Lesieur, D; Poupaert, JH; Yous, S | 1 |
| Bianchi, M; Panerai, AE | 1 |
2 trial(s) available for thiazoles and Allodynia
| Article | Year |
|---|---|
Characterization of osteoarthritis in cats and meloxicam efficacy using objective chronic pain evaluation tools.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cat Diseases; Cats; Chronic Pain; Dose-Response Relationship, Drug; Female; Hyperalgesia; Male; Meloxicam; Osteoarthritis; Pain Measurement; Thiazines; Thiazoles | 2013 |
Analgesic and antihyperalgesic effects of dipyrone, meloxicam or a dipyrone-meloxicam combination in bitches undergoing ovariohysterectomy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Dogs; Double-Blind Method; Drug Therapy, Combination; Female; Hyperalgesia; Hysterectomy; Meloxicam; Ovariectomy; Pain, Postoperative; Thiazines; Thiazoles | 2015 |
38 other study(ies) available for thiazoles and Allodynia
| Article | Year |
|---|---|
Notch1 Signaling Contributes to Mechanical Allodynia Associated with Cyclophosphamide-Induced Cystitis by Promoting Microglia Activation and Neuroinflammation.
Topics: Animals; Cyclophosphamide; Cystitis; Diamines; Female; Hyperalgesia; Interleukin-1beta; Microglia; Neuroinflammatory Diseases; Rats; Rats, Sprague-Dawley; Receptor, Notch1; Signal Transduction; Thiazoles; Tumor Necrosis Factor-alpha | 2021 |
Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic.
Topics: Analgesics; Animals; Capsaicin; CHO Cells; Cricetulus; Drug Discovery; Hyperalgesia; Mice, Inbred ICR; Neuralgia; Phenylurea Compounds; Swine; Thiazoles; TRPV Cation Channels | 2020 |
Antihyperalgesic effects of intrathecal perospirone in a rat model of neuropathic pain.
Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Spinal; Isoindoles; Male; Neuralgia; Pain Measurement; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Rotarod Performance Test; Serotonin 5-HT1 Receptor Antagonists; Signal Transduction; Thiazoles | 2020 |
The Role of TMEM16A/ERK/NK-1 Signaling in Dorsal Root Ganglia Neurons in the Development of Neuropathic Pain Induced by Spared Nerve Injury (SNI).
Topics: Animals; Anoctamins; Butadienes; Chronic Pain; Extracellular Signal-Regulated MAP Kinases; Ganglia, Spinal; Hyperalgesia; Ligation; Male; Neuralgia; Nitriles; Nociception; Peroneal Nerve; Pyrimidines; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Sensory Receptor Cells; Signal Transduction; Thiazoles; Tibial Nerve | 2021 |
Sensitization of TRPV1 and TRPA1 via peripheral mGluR5 signaling contributes to thermal and mechanical hypersensitivity.
Topics: Acetanilides; Animals; Disease Models, Animal; Enzyme Inhibitors; Freund's Adjuvant; Glutamic Acid; Glycine; Hyperalgesia; Male; Neurons; Pain; Pain Threshold; Phenylacetates; Physical Stimulation; Purines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Signal Transduction; Skin; Thiazoles; Trigeminal Ganglion; TRPA1 Cation Channel; TRPV Cation Channels | 2017 |
A novel composite formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models.
Topics: Administration, Oral; Amides; Animals; Anti-Inflammatory Agents; Carrageenan; Drug Combinations; Edema; Ethanolamines; Hyperalgesia; Inflammation; Male; Meloxicam; Osteoarthritis; Pain; Palmitic Acids; Quercetin; Rats, Sprague-Dawley; Thiazines; Thiazoles | 2017 |
Therapeutic potential for leukocyte elastase in chronic pain states harboring a neuropathic component.
Topics: Analgesics; Animals; Cancer Pain; Chronic Pain; Cyclic S-Oxides; Disease Models, Animal; Female; Glycine; Hyperalgesia; Leukocyte Elastase; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; Neuralgia; Pain Measurement; Pain Threshold; Pregabalin; Serine Proteinase Inhibitors; Sulfonamides; Thiazoles | 2017 |
Blockade of anoctamin-1 in injured and uninjured nerves reduces neuropathic pain.
Topics: Activating Transcription Factor 3; Animals; Anoctamin-1; Caspase 3; Disease Models, Animal; Female; Ganglia, Spinal; Hyperalgesia; Injections, Spinal; Ligation; Neuralgia; Pyrimidines; Rats; Rats, Wistar; Spinal Nerves; Thiazoles | 2018 |
Chloride Dysregulation through Downregulation of KCC2 Mediates Neuropathic Pain in Both Sexes.
Topics: Acetazolamide; Animals; Brain-Derived Neurotrophic Factor; Carbonic Anhydrase Inhibitors; Chlorides; Down-Regulation; Female; Hyperalgesia; K Cl- Cotransporters; Male; Mice; Mice, Inbred C57BL; Neuralgia; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Sex Characteristics; Spinal Cord; Symporters; Thiazoles; Thioglycolates | 2019 |
Glycogen synthase kinase 3 beta regulates glial glutamate transporter protein expression in the spinal dorsal horn in rats with neuropathic pain.
Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; Disease Models, Animal; Drug Administration Routes; Enzyme Inhibitors; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hyperalgesia; Interleukin-1beta; Male; Neurons; Oncogene Protein v-akt; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatica; Serine; Spinal Cord; Thiazoles; Time Factors; Urea | 2014 |
Alleviation of behavioral hypersensitivity in mouse models of inflammatory pain with two structurally different casein kinase 1 (CK1) inhibitors.
Topics: Animals; Carrageenan; Casein Kinase I; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Humans; Hyperalgesia; Indoles; Inflammation; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Pain; Pain Measurement; Pain Threshold; Phloroglucinol; Protein Transport; Spinal Cord; Thiazoles | 2014 |
Thermal nociceptive threshold testing detects altered sensory processing in broiler chickens with spontaneous lameness.
Topics: Analgesics; Animals; Butorphanol; Chickens; Female; Hyperalgesia; Lameness, Animal; Male; Meloxicam; Nociception; Poultry Diseases; Sensation; Skin Temperature; Thiazines; Thiazoles | 2014 |
Reduction of spinal PGE2 concentrations prevents swim stress-induced thermal hyperalgesia.
Topics: Animals; Biomarkers; Corticosterone; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Escape Reaction; Hot Temperature; Hyperalgesia; Ketoprofen; Male; Meloxicam; Rats, Sprague-Dawley; Spinal Cord; Stress, Psychological; Swimming; Thiazines; Thiazoles | 2015 |
Protease-activated receptor 2 activation is sufficient to induce the transition to a chronic pain state.
Topics: Animals; Azepines; Behavior, Animal; Benzamides; Brain-Derived Neurotrophic Factor; Butadienes; Chronic Pain; Dinoprostone; Disease Models, Animal; Facial Expression; Hydrazones; Hyperalgesia; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Nitriles; Protein Kinase C; Receptor, PAR-2; Receptor, trkB; Signal Transduction; Thiazoles | 2015 |
Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Hyperalgesia; K Cl- Cotransporters; Male; Mice; Pain Threshold; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sciatica; Signal Transduction; Spinal Nerve Roots; Symporters; Thiazoles; Thioglycolates | 2015 |
Design, synthesis, and anti-inflammatory evaluation of novel diphenylthiazole-thiazolidinone hybrids.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Design; Edema; Hyperalgesia; Mice; Molecular Docking Simulation; Protein Binding; Thiazoles | 2015 |
Evaluation of the local inflammatory events induced by BpirMP, a metalloproteinase from Bothrops pirajai venom.
Topics: Animals; Bothrops; Cell Degranulation; Cromolyn Sodium; Crotalid Venoms; Cyclooxygenase Inhibitors; Edema; Female; Histamine H1 Antagonists; Hyperalgesia; Inflammation; Interleukin-10; Interleukin-6; Leukocytes; Male; Mast Cells; Meloxicam; Metalloproteases; Mice; Mice, Inbred BALB C; Nitric Oxide; Nociception; Pyrilamine; Rats; Rats, Wistar; Salicylates; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha; Viper Venoms | 2015 |
DF2755A, a novel non-competitive allosteric inhibitor of CXCR1/2, reduces inflammatory and post-operative pain.
Topics: Adult; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cell Line, Tumor; Cell Movement; Cells, Cultured; Chemokine CXCL1; Dinoprostone; Guinea Pigs; Humans; Hyperalgesia; Interleukin-8; Leukocytes, Mononuclear; Macrophages, Peritoneal; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Pain, Postoperative; Phenylacetates; Physical Stimulation; Rabbits; Rats; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Thiazoles | 2016 |
Non-steroidal Anti-inflammatory Drugs Attenuate Hyperalgesia and Block Upregulation of Trigeminal Ganglionic Sodium Channel 1.7 after Induction of Temporomandibular Joint Inflammation in Rats.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Diclofenac; Eating; Female; Freund's Adjuvant; Hyperalgesia; Ibuprofen; Meloxicam; NAV1.7 Voltage-Gated Sodium Channel; Nociception; Pain Threshold; Rats; Rats, Sprague-Dawley; Synovial Membrane; Temporomandibular Joint; Temporomandibular Joint Disorders; Thiazines; Thiazoles; Trigeminal Ganglion; Up-Regulation | 2016 |
Involvement of c-Myc-mediated transient receptor potential melastatin 8 expression in oxaliplatin-induced cold allodynia in mice.
Topics: Animals; Benzyl Compounds; Ganglia, Spinal; Hyperalgesia; Male; Mice; Organoplatinum Compounds; Oxaliplatin; Proto-Oncogene Proteins c-myc; Skin; Thiazoles; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; Urea | 2016 |
Identification and synthesis of 2,7-diamino-thiazolo[5,4-d]pyrimidine derivatives as TRPV1 antagonists.
Topics: Administration, Oral; Animals; Hyperalgesia; Pyrimidines; Rats; Structure-Activity Relationship; Thiazoles; Treatment Outcome; TRPV Cation Channels | 2009 |
Influence on analgesic activity and serum levels after meloxicam complexation with beta-cyclodextrin in mice and rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Carrageenan; Hyperalgesia; Male; Meloxicam; Mice; Pain; Pain Measurement; Rats; Rats, Wistar; Thiazines; Thiazoles; Veins | 2010 |
Characterization of 2-(2,6-dichloro-benzyl)-thiazolo[5,4-d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine (JNJ-39729209) as a novel TRPV1 antagonist.
Topics: Animals; Body Temperature; Cell Line; Clinical Trials as Topic; Cough; Dogs; Female; Guinea Pigs; Humans; Hyperalgesia; Hypotension; Male; Mice; Pyrimidines; Rats; Thiazoles; TRPV Cation Channels | 2011 |
The kappa opioid receptor agonist SA14867 has antinociceptive and weak sedative effects in models of acute and chronic pain.
Topics: Acetamides; Acute Pain; Analgesics; Animals; Arthritis; Chronic Pain; Disease Models, Animal; Hyperalgesia; Hypnotics and Sedatives; Ligation; Male; Mice; Morphine; Neuralgia; Pain Threshold; Pyrrolidines; Receptors, Opioid, kappa; Sciatic Nerve; Stress, Physiological; Tartrates; Temperature; Thiazoles | 2011 |
Glycogen synthase kinase 3-specific inhibitor AR-A014418 decreases neuropathic pain in mice: evidence for the mechanisms of action.
Topics: Analgesics; Animals; Arginine; Cytokines; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Hyperalgesia; Ligation; Male; Mice; Motor Activity; Neuralgia; Nitric Oxide; Pain Measurement; Parasympathetic Nervous System; Sciatic Neuropathy; Serotonin; Spinal Cord; Thiazoles; Urea | 2012 |
A thymulin analogue peptide with powerful inhibitory effects on pain of neurogenic origin.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Hyperalgesia; Ligation; Male; Meloxicam; Morphine; Pain; Pain Threshold; Peptides; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Reaction Time; Thiazines; Thiazoles; Thymic Factor, Circulating; Time Factors | 2003 |
Assessing the role of metabotropic glutamate receptor 5 in multiple nociceptive modalities.
Topics: Acetic Acid; Animals; Carrageenan; Central Nervous System; Constriction, Pathologic; Edema; Formaldehyde; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Motor Activity; Pain; Pain Measurement; Pain, Postoperative; Psychomotor Performance; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Spinal Nerves; Thiazoles; Vincristine | 2004 |
Anxiety and depression.
Topics: Aggression; Animals; Anti-Anxiety Agents; Antidepressive Agents; Humans; Hyperalgesia; Indoles; Pyrrolidines; Receptors, Opioid, delta; Thiazoles | 2005 |
Ameliorative effect of combined administration of inducible nitric oxide synthase inhibitor with cyclooxygenase-2 inhibitors in neuropathic pain in rats.
Topics: Animals; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Guanidines; Hyperalgesia; Lactones; Male; Meloxicam; Neuralgia; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase Type II; Nociceptors; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Reaction Time; Sciatic Neuropathy; Sulfones; Thiazines; Thiazoles; Treatment Outcome | 2007 |
S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance.
Topics: Adrenalectomy; Analgesics; Animals; Arginine; Dipyrone; Drug Tolerance; Edema; Endorphins; Fever; Hyperalgesia; Indomethacin; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Pain Measurement; Rats; Rats, Wistar; Thiazoles; Yohimbine | 1995 |
Central antinociceptive effects of meloxicam on rat spinal cord in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Electric Stimulation; Female; Hindlimb; Hyperalgesia; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Meloxicam; Membrane Proteins; Pain; Perfusion; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Spinal Cord; Spinal Nerve Roots; Thiazines; Thiazoles | 1998 |
Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Gastric Mucosa; Humans; Hyperalgesia; Isoenzymes; Male; Membrane Proteins; Mice; Oxazoles; Phenols; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship; Thiazoles | 1999 |
Thymulin induces c-fos expression in the spinal cord of rats which is reversed by meloxicam and morphine.
Topics: Animals; Antibodies; Cyclooxygenase Inhibitors; Hot Temperature; Hyperalgesia; Meloxicam; Morphine; Narcotics; Peripheral Nerves; Physical Stimulation; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Thiazines; Thiazoles; Thymic Factor, Circulating | 1999 |
Hyperalgesia due to nerve injury: role of prostaglandins.
Topics: Animals; Cyclooxygenase Inhibitors; Functional Laterality; Hindlimb; Hyperalgesia; Indomethacin; Male; Meloxicam; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Sciatic Nerve; Thiazines; Thiazoles; Time Factors | 1999 |
The role of cytokines and prostaglandin-E(2) in thymulin induced hyperalgesia.
Topics: Analgesics, Non-Narcotic; Animals; Cytokines; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Immune Sera; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Male; Meloxicam; Nerve Growth Factor; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Thiazines; Thiazoles; Thymic Factor, Circulating; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
Analgesic activity of a novel use-dependent sodium channel blocker, crobenetine, in mono-arthritic rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzomorphans; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Meloxicam; Mexiletine; Pain; Pain Measurement; Posture; Rats; Rats, Wistar; Sodium Channel Blockers; Thiazines; Thiazoles | 2001 |
Synthesis and pharmacological evaluation of analgesic 6-substituted 2(3H)-benzothiazolones.
Topics: Analgesics; Animals; Benzothiazoles; Drug Evaluation, Preclinical; Hyperalgesia; Mice; Pain Measurement; Stomach Ulcer; Thiazoles | 2001 |
Effects of lornoxicam, piroxicam, and meloxicam in a model of thermal hindpaw hyperalgesia induced by formalin injection in rat tail.
Topics: Analgesics, Non-Narcotic; Animals; Formaldehyde; Hindlimb; Hyperalgesia; Inflammation; Male; Meloxicam; Pain Threshold; Piroxicam; Rats; Rats, Sprague-Dawley; Tail; Thiazines; Thiazoles | 2002 |