thiazoles and Allergic Encephalomyelitis

Topics: Animals; Bystander Effect; Drug Combinations; Encephalomyelitis, Autoimmune, Experimental; Epitopes, T-Lymphocyte; Female; Humans; Immune Tolerance; Immunosuppressive Agents; Indoles; Liposomes; Mice; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Nanoparticles; Peptide Fragments; Receptors, Aryl Hydrocarbon; Signal Transduction; T-Lymphocytes, Regulatory; Thiazoles

Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Inflammation Mediators; Mice; Mice, Inbred C57BL; Sphingosine 1 Phosphate Receptor Modulators; T-Lymphocytes, Regulatory; Th1 Cells; Th17 Cells; Thiazoles

Topics: Animals; Brain; Catalytic Domain; CD3 Complex; Computer Simulation; Encephalomyelitis, Autoimmune, Experimental; Hydrolases; Imidazoles; Indoles; Mice; Models, Molecular; Multiple Sclerosis; Pilot Projects; Piperazines; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Pyridines; Pyrimidines; Small Molecule Libraries; Stereoisomerism; T-Lymphocytes; Thiazoles

Topics: Amino Acid Sequence; Amyloid; Animals; Benzothiazoles; Biotinylation; Blood Proteins; Chemical Precipitation; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Hydrogen-Ion Concentration; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; Molecular Chaperones; Molecular Sequence Data; Nervous System; Paralysis; Peptides; Protein Multimerization; Thiazoles

Topics: Animals; Axons; Central Nervous System; Encephalomyelitis, Autoimmune, Experimental; Febuxostat; Female; Mice; Multiple Sclerosis; Myelin Sheath; Reactive Oxygen Species; Thiazoles; Xanthine Oxidase

Topics: Aniline Compounds; Animals; Benzothiazoles; Encephalomyelitis, Autoimmune, Experimental; Male; Multiple Sclerosis; Myelin Sheath; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Stilbenes; Thiazoles

Topics: Acrylamides; Active Transport, Cell Nucleus; Animals; Axons; Cell Nucleus; Cells, Cultured; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Exportin 1 Protein; Female; Karyopherins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Proteomics; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thiazoles; Treatment Outcome

Topics: Animals; Blood-Brain Barrier; CD11b Antigen; Cell Movement; Cerebral Cortex; Cytokines; Disease Models, Animal; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Gene Expression Regulation; Inflammation Mediators; Integrin alpha4beta1; Leukocyte Common Antigens; Leukocytes; Male; Mice; Monocytes; Multiple Sclerosis; Nitro Compounds; Oligopeptides; Permeability; RNA, Messenger; Thiazoles

Topics: Animals; Dexamethasone; Dimethyl Fumarate; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Fingolimod Hydrochloride; Immunologic Factors; Phenotype; Sulfonamides; Thiazoles; Video Recording; Zebrafish

Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; HEK293 Cells; Humans; Interleukin-17; Interleukin-6; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Pyrazoles; Thiazoles

Topics: Animals; Anti-Inflammatory Agents; Antibodies; Astrocytes; Brain; Cells, Cultured; Demyelinating Diseases; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Glial Fibrillary Acidic Protein; Interferon-gamma; Interleukin-6; Lipopolysaccharides; Microglia; Myelin Basic Protein; Neurofilament Proteins; Nitric Oxide Synthase Type II; PPAR gamma; PPAR-beta; Rats; Thiazoles; Tumor Necrosis Factor-alpha

Topics: Animals; Bone Morphogenetic Proteins; Carrier Proteins; Cells, Cultured; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligodendroglia; Pioglitazone; PPAR delta; Stem Cells; Thiazoles; Thiazolidinediones

Topics: Animals; Cell Polarity; Cells, Cultured; Encephalomyelitis, Autoimmune, Experimental; Female; Interleukin-17; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenoxyacetates; PPAR delta; T-Lymphocytes, Helper-Inducer; Th1 Cells; Thiazoles

Topics: Animals; Brain; CD4-Positive T-Lymphocytes; Cell Proliferation; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression; Glycoproteins; Homeodomain Proteins; Humans; Interferon-gamma; Interleukin-12; Interleukin-17; Leukocytes, Mononuclear; Lipopolysaccharides; Lymphocyte Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelin-Oligodendrocyte Glycoprotein; Myeloid Cells; Nuclear Receptor Subfamily 1, Group F, Member 3; Peptide Fragments; PPAR delta; Spinal Cord; T-Box Domain Proteins; T-Lymphocytes, Helper-Inducer; Th1 Cells; Thiazoles; Tumor Necrosis Factor-alpha

Topics: Adoptive Transfer; Animals; Cell Compartmentation; Cell Differentiation; Dendritic Cells; Encephalomyelitis, Autoimmune, Experimental; Forkhead Transcription Factors; Immune Tolerance; Indoles; Ligands; Mice; Mice, Inbred C57BL; Receptors, Aryl Hydrocarbon; T-Lymphocytes, Regulatory; Thiazoles; Tretinoin

Topics: Animals; Bone Marrow Transplantation; Cell Differentiation; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Immunomodulation; Indoleamine-Pyrrole 2,3,-Dioxygenase; Meloxicam; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Thiazines; Thiazoles

Topics: Animals; CD13 Antigens; CD4-Positive T-Lymphocytes; Cells, Cultured; Chemokine CXCL12; Chemotaxis; Dipeptidyl Peptidase 4; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Female; Humans; Hydroxamic Acids; Lymphocyte Activation; Lysine; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Pyrroles; Pyrrolidines; Thiazoles; Transgenes

Topics: Adoptive Transfer; Animals; Benzodiazepines; CD4-Positive T-Lymphocytes; Cell Differentiation; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation; Histones; Mice; Mice, Inbred C57BL; Microarray Analysis; Nuclear Proteins; Phosphorylation; Positive Transcriptional Elongation Factor B; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Salivary alpha-Amylases; Thiazoles; Transcription Factors; Transcription, Genetic

Topics: Animals; Cerebellum; Cerebral Cortex; DNA-Binding Proteins; Encephalomyelitis, Autoimmune, Experimental; Female; Glycoproteins; Humans; Hypoglycemic Agents; I-kappa B Proteins; Ligands; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxazoles; Peptide Fragments; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Remission Induction; Spinal Cord; T-Lymphocytes; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine

Topics: Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cytokines; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Profiling; Gene Expression Regulation; Glycoproteins; Hydroxamic Acids; Immunohistochemistry; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Neurons; Oligonucleotide Array Sequence Analysis; Peptide Fragments; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Severity of Illness Index; Spleen; Tetrazolium Salts; Thiazoles; Time Factors

Topics: Animals; Brain; Concanavalin A; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Enzymologic; Glycoproteins; Immunohistochemistry; Interferon-gamma; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred C57BL; Myelin Basic Protein; Myelin-Oligodendrocyte Glycoprotein; Neuroglia; Peptide Fragments; PPAR delta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Severity of Illness Index; Thiazoles; Time Factors

Topics: Animals; Antibodies; CD13 Antigens; Cell Proliferation; Dipeptidyl-Peptidase IV Inhibitors; Drug Synergism; Drug Therapy, Combination; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Hydroxamic Acids; Immunosuppressive Agents; Leukocytes, Mononuclear; Lymphocyte Activation; Lysine; Mice; Mice, Inbred Strains; Myelin Proteolipid Protein; Peptide Fragments; Phytohemagglutinins; Pokeweed Mitogens; Protease Inhibitors; Pyrrolidines; T-Lymphocytes; Thiazoles; Transforming Growth Factor beta1; Vaccination

Topics: Animals; Antigens, CD; Cell Proliferation; Cytokines; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Flow Cytometry; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Phenylurea Compounds; Protein Kinase Inhibitors; Spinal Cord; T-Lymphocytes; Thiazoles; Time Factors

Topics: Animals; Animals, Outbred Strains; Autoimmune Diseases; Dipeptidyl Peptidase 4; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Lymphocyte Activation; Lysine; Mice; Multiple Sclerosis; Myelin Basic Protein; Pyrrolidines; Rats; Serine Proteinase Inhibitors; T-Lymphocyte Subsets; T-Lymphocytes, Helper-Inducer; Thiazoles

Topics: Animals; Astrocytes; Brain; Cytoplasmic Granules; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Female; Immunohistochemistry; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Mixed Function Oxygenases; Multiple Sclerosis; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Spinal Cord; Sulfonamides; Thiazoles

Topics: Animals; Cell Division; Chromans; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Female; Inflammation Mediators; Mice; Mice, Inbred C57BL; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Receptors, Cytoplasmic and Nuclear; Reference Values; RNA, Messenger; T-Lymphocytes; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone

Topics: Animals; Cell Differentiation; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Immunologic Factors; Interleukin-12; Janus Kinase 2; Kinetics; Lymphocyte Activation; Macrophages; Mice; Microglia; Myelin Basic Protein; Prostaglandin D2; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Spinal Cord; Th1 Cells; Thiazoles; Thiazolidinediones; Transcription Factors

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Encephalomyelitis, Autoimmune, Experimental; Imidazoles; Rats; Rats, Inbred Lew; Thiazoles