thiazoles has been researched along with Age-Related Memory Disorders in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.82) | 18.7374 |
| 1990's | 3 (5.45) | 18.2507 |
| 2000's | 12 (21.82) | 29.6817 |
| 2010's | 38 (69.09) | 24.3611 |
| 2020's | 1 (1.82) | 2.80 |
| Authors | Studies |
|---|---|
| DeCarli, C; Farias, ST; Fletcher, E; Han, JW; Harvey, D; Jagust, W; Johnson, DK; Maillard, P; Martinez, O; Mungas, D; Olichney, JM; Villeneuve, S | 1 |
| Amariglio, RE; Hanseeuw, B; Johnson, KA; Marshall, GA; Munro, CE; Pascual-Leone, A; Rentz, DM; Sperling, RA; Vannini, P | 1 |
| Kuang, S; Li, H; Luo, Y; Ran, D; Yang, J | 1 |
| Bagni, C; D'Andrea, L; Huynh, TN; Klann, E; Koo, SY; Longo, F; Mojica, E; Santini, E | 1 |
| Aizenstein, HJ; Cohen, AD; DeKosky, ST; Kamboh, MI; Klunk, WE; Kuller, LH; Lopez, OL; Mathis, CA; Price, JC; Snitz, BE; Tudorascu, DL; Zhao, Y | 1 |
| Cao, Y; Gao, J; Hao, Y; Sun, C; Wang, J; Wu, H; Wu, L; Xia, W; Zhang, Q | 1 |
| Bell, RK; Jagust, WJ; Leal, SL; Lockhart, SN; Maass, A | 1 |
| Gao, Q; Jiao, WX; Lu, W; Miao, YZ; Sun, LL; Sun, Q; Wang, K; Wang, XT; Wei, NN; Yang, TY; Zhou, QQ | 1 |
| Adams, CE; Kwong, JS; Nyakyoma, K; Qi, F; Sinclair, DJ; Zhao, S | 1 |
| Chen, J; Fan, L; Guan, XW; Li, J; Lu, J; Lv, JL; Mao, F; Qiu, XX; Ren, J; Shen, X; Wang, JY; Ye, JM; Zhao, YH; Zhu, J; Zhu, ZY | 1 |
| Hwang, H; Rhim, H | 1 |
| Caselli, RJ; Chen, K; Dueck, AC; Fleisher, AS; Lee, W; Liu, X; Locke, DE; Reiman, EM; Roontiva, A; Stonnington, CM | 1 |
| Chertkow, H; Ducharme, S; Guiot, MC; Nikelski, J | 1 |
| Gao, J; Gräff, J; Kahn, M; Ota, KT; Rei, D; Samiei, A; Tsai, LH | 1 |
| Cho, H; Choe, YS; Ewers, M; Jeon, S; Kim, C; Kim, CH; Kim, GH; Kim, HJ; Kim, JS; Kim, SH; Kim, ST; Lee, JH; Lee, JM; Lee, KH; Na, DL; Noh, Y; Oh, SJ; Park, JH; Seo, SW; Shin, JS; Weiner, MW; Werring, DJ; Ye, BS; Yoon, CW | 1 |
| Ames, D; Darby, D; Ellis, KA; Harrington, K; Lim, YY; Martins, RN; Maruff, P; Masters, CL; Pietrzak, RH; Rowe, CC; Savage, G; Szoeke, C; Villemagne, VL | 1 |
| Adriaanse, S; Bouwman, F; Lammertsma, A; Ossenkoppele, R; Scheltens, P; Teunissen, C; van Berckel, B; van der Flier, W; van Harten, A; Zwan, M | 1 |
| Ames, D; Bourgeat, P; Ellis, KA; Harrington, K; Lim, YY; Martins, RN; Maruff, P; Masters, CL; Pietrzak, RH; Rembach, A; Rowe, CC; Salvado, O; Snyder, PJ; Villemagne, VL | 1 |
| Ancoli-Israel, S; Jagust, WJ; Lu, B; Mander, BA; Marks, SM; Rao, V; Saletin, JM; Vogel, JW; Walker, MP | 1 |
| Aschenbrenner, AJ; Balota, DA; Benzinger, TL; Duchek, JM; Fagan, AM; Morris, JC | 1 |
| An, YQ; Du, Y; Hong, H; Hu, M; Long, Y; Sun, HB; Tang, SS; Zhang, CT; Zhang, M | 1 |
| Alves, CB; Ferreira, CF; Ianiski, FR; Luchese, C; Rech, VC; Savegnago, L; Wilhelm, EA | 1 |
| Akanabe, H; Chikaishi, T; Hayakawa, M; Hayashi, Y; Inuzuka, T; Islam, S; Itoh, M; Itoh, Y; Kobori, M; Li, S; Mori, T; Muro, T; Nakabayashi, R; Nakagawa, K; Nakagawa, T; Nishida, E; Ohta, K; Ohzawa, K; Saito, K; Suzuki, C; Ueda, M; Wang, MX; Yamada, Y; Yanagida, D | 1 |
| Chin, J; Choe, YS; Chun, P; Jung, NY; Kim, C; Kim, HJ; Kim, JS; Kim, S; Kim, ST; Kim, YJ; Kwon, H; Lee, JH; Lee, JM; Lee, KH; Na, DL; Seo, SW; Weiner, MW; Woo, SY; Yang, JJ | 1 |
| Bark, JS; Betensky, RA; Chhatwal, JP; Cosio, DM; Hanseeuw, BJ; Johnson, KA; LaPoint, M; Mormino, EC; Papp, KV; Rentz, DM; Schultz, AP; Sepulcre, J; Sperling, RA | 1 |
| Danysz, W; Dekundy, A; Gravius, A; Morè, L; Nagel, J; Pietraszek, M | 1 |
| Baker, SL; Jagust, WJ; Kluth, JT; Koeppe, RA; Madison, CM; Mathis, CA; Miller, BL; Mormino, EC; Rabinovici, GD; Weiner, MW | 1 |
| Bero, AW; Csernansky, JG; Dong, H; Holtzman, DM; Kling, MJ; Timson, BF; Yuede, CM; Zimmerman, SD | 1 |
| Aalto, S; Arponen, E; Hirvonen, J; Immonen-Räihä, P; Koski, K; Lisinen, I; Rinne, JO; Seppänen, M; Sulkava, R; Suotunen, T; Teräs, M | 1 |
| Almkvist, O; Engler, H; Forsberg, A; Långström, B; Nordberg, A; Wall, A | 1 |
| Becker, JA; Buckner, RL; Eng, E; Johnson, KA; Locascio, JJ; Moran, EK; Rentz, DM; Sperling, RA | 1 |
| Enomoto, T; Horisawa, T; Ishibashi, T; Ishiyama, T; Nishikawa, H; Taiji, M; Toma, S | 1 |
| Ames, D; Bourgeat, P; Chételat, G; Ellis, KA; Jones, G; Martins, RN; Masters, CL; O'Keefe, GJ; Pike, KE; Rowe, CC; Salvado, O; Szoeke, C; Villemagne, VL | 1 |
| Amariglio, RE; Becker, JA; Carmasin, J; Frey, M; Frishe, K; Johnson, KA; Maye, JE; Olson, LE; Rentz, DM; Sperling, RA | 1 |
| Ataka, S; Miki, T; Mori, H; Shimada, H; Takechi, H; Tomiyama, T | 1 |
| Ames, D; Chételat, G; Ellis, KA; Masters, CL; Pike, KE; Rowe, CC; Villemagne, VL | 1 |
| Alves, CB; Alves, MP; Ianiski, FR; Luchese, C; Pinton, S; Rhoden, CR; Roman, SS; Souza, AC | 1 |
| Liu, RT; Wang, L; Wang, SW; Wang, YJ; Xue, D; Yang, Y; Zhang, R; Zhao, M; Zhao, Y | 1 |
| Gallagher, M; Koh, MT; Rosenzweig-Lipson, S | 1 |
| Ames, D; Ashwood, T; Bush, AI; Darby, D; Ellis, KA; Harrington, K; Jaeger, J; Lim, YY; Martins, RN; Maruff, P; Masters, CL; Pietrzak, RH; Rowe, CC; Szoeke, C; Villemagne, VL | 1 |
| Ames, D; Bush, AI; Ellis, KA; Faux, NG; Gupta, VB; Henley, D; Laws, SM; Li, QX; Martins, RN; Masters, CL; Pike, KE; Rowe, CC; Szoeke, C; Taddei, K; Verdile, G; Villemagne, VL | 1 |
| Aalten, P; Adriaanse, SF; Handels, RL; Hoekstra, OS; Lammertsma, AA; Lemstra, AW; Ossenkoppele, R; Pijnenburg, YA; Prins, ND; Scheltens, P; van Berckel, BN; van Buchem, MA; van der Flier, WM; Verbeek, MM; Verhey, FR; Windhorst, AD; Wolfs, CA | 1 |
| Bar-Ner, N; Brandeis, R; Egozi, I; Fisher, A; Haring, R; Kliger-Spatz, M; Marcovitch, I; Natan, N; Pittel, Z; Sonego, H | 1 |
| DeKosky, ST; Hoge, JA; Holt, DP; Klunk, WE; Lopresti, BJ; Lu, X; Mathis, CA; Meltzer, CC; Price, JC; Ziolko, SK | 1 |
| Billings, LM; Caccamo, A; Fisher, A; Green, KN; LaFerla, FM; Martinez-Coria, H; Oddo, S | 1 |
| Gong, Y; Hughes, JA; King, MA; Klein, RL; Meyer, EM; Meyers, CA | 1 |
| Enomoto, T; Ishibashi, T; Ishiyama, T; Ito, A; Tokuda, K; Toma, S | 1 |
| Bilder, RM; Galluzzo, A; Gorini, B; Harvey, PD; Loebel, AD; Romeo, F; Sacchetti, E | 1 |
| Iinuma, Y; Iwai, T; Kodani, R; Oka, J | 1 |
| Aldenkamp, AP; Beun, AM; Diepman, L; Edelbroek, P; Gutter, T; Mulder, OG; Overweg, J; Smakman, J; Vledder, B; vt Slot, B | 1 |
| Furushiro, M; Hashimoto, S; Nishiyama, S; Ohno, M; Shishido, Y; Tanabe, S; Watanabe, S; Yamamoto, T | 1 |
| Furushiro, M; Hashimoto, S; Shibata, S; Shishido, Y; Tanabe, S; Taniguchi, A; Watanabe, S; Yamamoto, T; Yokokura, T | 1 |
| Chen, Z; Kamei, C | 1 |
| Boyer, PA; De Nanteuil, G; Guez, D; Jochemsen, R; Lestage, P; Morain, P; Robin, JL | 1 |
| Robbins, TW | 1 |
4 review(s) available for thiazoles and Age-Related Memory Disorders
| Article | Year |
|---|---|
Electroconvulsive therapy for treatment-resistant schizophrenia.
Topics: Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Electroconvulsive Therapy; Female; Flupenthixol; Humans; Male; Memory Disorders; Patient Readmission; Piperazines; Randomized Controlled Trials as Topic; Schizophrenia; Standard of Care; Thiazoles; Treatment Outcome | 2019 |
Relationship between memory performance and β-amyloid deposition at different stages of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Atrophy; Brain; Humans; Magnetic Resonance Imaging; Memory Disorders; Positron-Emission Tomography; Thiazoles | 2012 |
M1 muscarinic agonists can modulate some of the hallmarks in Alzheimer's disease: implications in future therapy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cell Death; Disease Models, Animal; Down-Regulation; Humans; Memory Disorders; Mice; Muscarinic Agonists; Oxidative Stress; Piperidines; Quinuclidines; Receptor, Muscarinic M1; Spiro Compounds; tau Proteins; Thiazoles; Thiophenes | 2003 |
S 17092: a prolyl endopeptidase inhibitor as a potential therapeutic drug for memory impairment. Preclinical and clinical studies.
Topics: Aging; Animals; Cognition Disorders; Humans; Indoles; Learning; Memory Disorders; Models, Animal; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Substance P; Thiazoles; Thiazolidines | 2002 |
4 trial(s) available for thiazoles and Age-Related Memory Disorders
| Article | Year |
|---|---|
A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration.
Topics: Analysis of Variance; Animals; Atrophy; Brain; Caloric Restriction; Case-Control Studies; Cognition Disorders; Cyclin-Dependent Kinase 5; Disease Models, Animal; Double-Blind Method; Excitatory Postsynaptic Potentials; Female; Green Fluorescent Proteins; Immunoprecipitation; In Vitro Techniques; Long-Term Potentiation; Male; Memory Disorders; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Nerve Tissue Proteins; Neurodegenerative Diseases; Phosphopyruvate Hydratase; Phosphotransferases; Piperidines; Silver Staining; Sirtuin 1; Synapses; Thiazoles; Tumor Suppressor Protein p53; Vitamin E | 2013 |
Impact of molecular imaging on the diagnostic process in a memory clinic.
Topics: Aged; Alzheimer Disease; Aniline Compounds; Brain; Carbon Radioisotopes; Dementia; Diagnosis, Differential; Disease Progression; Early Diagnosis; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Follow-Up Studies; France; Frontotemporal Dementia; Humans; Lewy Body Disease; Male; Memory Disorders; Middle Aged; Molecular Imaging; Outpatient Clinics, Hospital; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Sensitivity and Specificity; Thiazoles; Treatment Outcome | 2013 |
A randomized double-blind comparison of ziprasidone vs. clozapine for cognition in patients with schizophrenia selected for resistance or intolerance to previous treatment.
Topics: Adult; Antipsychotic Agents; Clozapine; Cognition Disorders; Double-Blind Method; Drug Resistance; Drug Tolerance; Female; Humans; Italy; Male; Memory Disorders; Neuropsychological Tests; Piperazines; Placebos; Schizophrenia; Schizophrenic Psychology; Thiazoles; Trail Making Test; Treatment Outcome | 2008 |
Effect of sabeluzole (R 58,735) on memory functions in patients with epilepsy.
Topics: Adult; Affect; Cognition; Double-Blind Method; Epilepsy; Female; Functional Laterality; Humans; Intelligence Tests; Male; Memory; Memory Disorders; Memory, Short-Term; Neuropsychological Tests; Piperidines; Psychomotor Performance; Reaction Time; Speech; Thiazoles | 1995 |
47 other study(ies) available for thiazoles and Age-Related Memory Disorders
| Article | Year |
|---|---|
Association of vascular brain injury, neurodegeneration, amyloid, and cognitive trajectory.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Brain; Cerebrovascular Disorders; Cognition; Cognitive Dysfunction; Disease Progression; Executive Function; Female; Hippocampus; Humans; Independent Living; Magnetic Resonance Imaging; Male; Memory Disorders; Memory, Episodic; Neuropsychological Tests; Organ Size; Plaque, Amyloid; Positron-Emission Tomography; Thiazoles; White Matter | 2020 |
Hippocampal hypometabolism in older adults with memory complaints and increased amyloid burden.
Topics: Aged; Amyloid beta-Peptides; Aniline Compounds; Apolipoprotein E4; Brain Mapping; Female; Fluorodeoxyglucose F18; Hippocampus; Humans; Limbic System; Male; Memory; Memory Disorders; Mental Status Schedule; Neuropsychological Tests; Parietal Lobe; Positron-Emission Tomography; Radiopharmaceuticals; Rest; Surveys and Questionnaires; Thiazoles | 2017 |
cAMP/PKA-CREB-BDNF signaling pathway in hippocampus mediates cyclooxygenase 2-induced learning/memory deficits of rats subjected to chronic unpredictable mild stress.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Inflammation Mediators; Learning; Meloxicam; Memory; Memory Disorders; Rats; Signal Transduction; Stress, Psychological; Synapses; Thiazines; Thiazoles | 2017 |
Reducing eIF4E-eIF4G interactions restores the balance between protein synthesis and actin dynamics in fragile X syndrome model mice.
Topics: Actins; Adaptor Proteins, Signal Transducing; Animals; Dendritic Spines; Disease Models, Animal; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4G; Fragile X Mental Retardation Protein; Fragile X Syndrome; Hippocampus; Hydrazones; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Thiazoles | 2017 |
Amyloid β Deposition and Suspected Non-Alzheimer Pathophysiology and Cognitive Decline Patterns for 12 Years in Oldest Old Participants Without Dementia.
Topics: Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Atrophy; Cognition Disorders; Female; Hippocampus; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Memory Disorders; Neuropsychological Tests; Positron-Emission Tomography; Retrospective Studies; Thiazoles | 2018 |
Modulation of sphingosine 1-phosphate (S1P) attenuates spatial learning and memory impairments in the valproic acid rat model of autism.
Topics: Analysis of Variance; Animals; Apoptosis; Autistic Disorder; Autophagy; Biomarkers; Disease Models, Animal; Hippocampus; Humans; Lysophospholipids; Male; Memory Disorders; Neurons; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Wistar; Signal Transduction; Spatial Learning; Sphingosine; Thiazoles; Valproic Acid | 2018 |
Subthreshold Amyloid Predicts Tau Deposition in Aging.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Biomarkers; Carbolines; Cerebral Cortex; Disease Progression; Female; Humans; Magnetic Resonance Imaging; Male; Memory Disorders; Neuropsychological Tests; Positron-Emission Tomography; Radiopharmaceuticals; Reference Values; tau Proteins; Thiazoles | 2018 |
Pharmacological characterization of JWX-A0108 as a novel type I positive allosteric modulator of α7 nAChR that can reverse acoustic gating deficits in a mouse prepulse inhibition model.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Dizocilpine Maleate; Hippocampus; Humans; Interneurons; Locomotion; Male; Maze Learning; Memory Disorders; Mice, Inbred C57BL; Nootropic Agents; Prepulse Inhibition; Rats, Sprague-Dawley; Schizophrenia; Sensory Gating; Synaptic Transmission; Thiazoles; Xenopus | 2019 |
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antiparasitic Agents; Cells, Cultured; Disease Models, Animal; Humans; Learning; Memory Disorders; Mice; Nitro Compounds; Thiazoles | 2019 |
Acutely elevated O-GlcNAcylation suppresses hippocampal activity by modulating both intrinsic and synaptic excitability factors.
Topics: Acetylglucosamine; Animals; beta-N-Acetylhexosaminidases; CA1 Region, Hippocampal; Cells, Cultured; Cognitive Dysfunction; Excitatory Postsynaptic Potentials; Humans; Intravital Microscopy; Male; Memory Disorders; Mice; Models, Animal; N-Acetylglucosaminyltransferases; Neurons; Optical Imaging; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Primary Cell Culture; Protein Processing, Post-Translational; Pyrans; Rats; Receptors, AMPA; Synapses; Thiazoles; Voltage-Gated Sodium Channels | 2019 |
Fibrillar amyloid correlates of preclinical cognitive decline.
Topics: Aged; Amyloid; Aniline Compounds; Apolipoprotein E4; Brain; Brain Mapping; Cognition Disorders; Female; Humans; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Observation; Positron-Emission Tomography; Prospective Studies; Thiazoles | 2014 |
Does a positive Pittsburgh Compound B scan in a patient with dementia equal Alzheimer disease?
Topics: Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Cerebral Hemorrhage; Diagnosis, Differential; Fatal Outcome; Humans; Magnetic Resonance Imaging; Male; Memory Disorders; Neuropsychological Tests; Positron-Emission Tomography; Sensitivity and Specificity; Thiazoles | 2013 |
Effects of cerebrovascular disease and amyloid beta burden on cognition in subjects with subcortical vascular cognitive impairment.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Brain; Cerebrovascular Disorders; Cognition Disorders; Female; Humans; Magnetic Resonance Imaging; Male; Memory Disorders; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles | 2014 |
Aβ and cognitive change: examining the preclinical and prodromal stages of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Cognition Disorders; Disease Progression; Female; Follow-Up Studies; Humans; Learning; Linear Models; Male; Memory Disorders; Memory, Short-Term; Neuropsychological Tests; Positron-Emission Tomography; Prodromal Symptoms; Psychiatric Status Rating Scales; Thiazoles | 2014 |
Concordance between cerebrospinal fluid biomarkers and [11C]PIB PET in a memory clinic cohort.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Cohort Studies; Female; Humans; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Peptide Fragments; Positron-Emission Tomography; Psychiatric Status Rating Scales; tau Proteins; Thiazoles | 2014 |
Relationships between performance on the Cogstate Brief Battery, neurodegeneration, and Aβ accumulation in cognitively normal older adults and adults with MCI.
Topics: Aged; Aged, 80 and over; Aging; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Atrophy; Carbon Isotopes; Cognitive Dysfunction; Female; Hippocampus; Humans; Linear Models; Magnetic Resonance Imaging; Male; Memory Disorders; Memory, Short-Term; Middle Aged; Nerve Degeneration; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles; Time Factors | 2015 |
β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Brain Waves; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Memory Disorders; Memory, Episodic; Polysomnography; Positron-Emission Tomography; Prefrontal Cortex; Recognition, Psychology; Sleep Stages; Sleep Wake Disorders; Thiazoles | 2015 |
Alzheimer Disease Cerebrospinal Fluid Biomarkers Moderate Baseline Differences and Predict Longitudinal Change in Attentional Control and Episodic Memory Composites in the Adult Children Study.
Topics: Aged; Alzheimer Disease; Aniline Compounds; Attention Deficit Disorder with Hyperactivity; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; Humans; Longitudinal Studies; Male; Memory Disorders; Memory, Episodic; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Predictive Value of Tests; Psychiatric Status Rating Scales; Thiazoles | 2015 |
PPARδ agonist GW0742 ameliorates Aβ1-42-induced hippocampal neurotoxicity in mice.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Caspase 3; Hippocampus; Interleukin-1beta; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred ICR; Neurons; Neuroprotective Agents; NF-kappa B; Peptide Fragments; PPAR delta; Thiazoles; Tumor Necrosis Factor-alpha | 2016 |
Meloxicam-loaded nanocapsules as an alternative to improve memory decline in an Alzheimer's disease model in mice: involvement of Na(+), K(+)-ATPase.
Topics: Alzheimer Disease; Animals; Behavior, Animal; Cerebral Cortex; Cyclooxygenase 2; Disease Models, Animal; Hippocampus; Meloxicam; Memory; Memory Disorders; Mice; Nanocapsules; Sodium-Potassium-Exchanging ATPase; Thiazines; Thiazoles | 2016 |
Improvement of memory recall by quercetin in rodent contextual fear conditioning and human early-stage Alzheimer's disease patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Animals; Antioxidants; Benzothiazoles; Conditioning, Psychological; Fear; Female; Humans; Iofetamine; Magnetic Resonance Imaging; Male; Memory Disorders; Mental Recall; Mental Status and Dementia Tests; Mice; Mice, Inbred C57BL; Neuropsychological Tests; Positron-Emission Tomography; Quercetin; Thiazoles | 2016 |
Relative impact of amyloid-β, lacunes, and downstream imaging markers on cognitive trajectories.
Topics: Aged; Amyloid beta-Peptides; Aniline Compounds; Cerebral Cortex; Cerebral Small Vessel Diseases; Cognitive Dysfunction; Executive Function; Female; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Memory Disorders; Positron-Emission Tomography; Stroke, Lacunar; Thiazoles | 2016 |
Fluorodeoxyglucose metabolism associated with tau-amyloid interaction predicts memory decline.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Cerebral Cortex; Female; Fluorodeoxyglucose F18; Humans; Male; Memory Disorders; Palmitates; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; tau Proteins; Thiazoles; Thiones | 2017 |
Investigation on tolerance development to subchronic blockade of mGluR5 in models of learning, anxiety, and levodopa-induced dyskinesia in rats.
Topics: Animals; Antiparkinson Agents; Anxiety Disorders; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Glutamic Acid; Learning Disabilities; Levodopa; Male; Maze Learning; Memory Disorders; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Synaptic Transmission; Thiazoles | 2008 |
Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects.
Topics: Age Factors; Aged; Aging; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Atrophy; Carbon Radioisotopes; Case-Control Studies; Educational Status; Female; Hippocampus; Humans; Linear Models; Magnetic Resonance Imaging; Male; Memory Disorders; Middle Aged; Multivariate Analysis; Organ Size; Positron-Emission Tomography; Psychiatric Status Rating Scales; Radiopharmaceuticals; Sex Factors; Thiazoles | 2009 |
Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Cerebral Cortex; Disease Models, Animal; Hippocampus; Humans; Memory; Memory Disorders; Mice; Mice, Transgenic; Organ Size; Peptide Fragments; Physical Conditioning, Animal; Protease Nexins; Random Allocation; Receptors, Cell Surface; Recognition, Psychology; Thiazoles; Time Factors | 2009 |
Visual assessment of [(11)C]PIB PET in patients with cognitive impairment.
Topics: Aged; Aged, 80 and over; Aniline Compounds; Benzothiazoles; Cognition Disorders; Dementia; Female; Humans; Male; Memory Disorders; Middle Aged; Positron-Emission Tomography; Reference Standards; Thiazoles | 2010 |
High PIB retention in Alzheimer's disease is an early event with complex relationship with CSF biomarkers and functional parameters.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Benzothiazoles; Biomarkers; Early Diagnosis; Enzyme-Linked Immunosorbent Assay; Female; Fluorodeoxyglucose F18; Glucose; Humans; Image Interpretation, Computer-Assisted; Male; Memory Disorders; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2010 |
Cognition, reserve, and amyloid deposition in normal aging.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Aniline Compounds; Benzothiazoles; Cognition; Cognition Disorders; Disability Evaluation; Disease Progression; Female; Humans; Longitudinal Studies; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Plaque, Amyloid; Positron-Emission Tomography; Predictive Value of Tests; Reference Values; Severity of Illness Index; Thiazoles | 2010 |
The effects of selective antagonists of serotonin 5-HT7 and 5-HT1A receptors on MK-801-induced impairment of learning and memory in the passive avoidance and Morris water maze tests in rats: mechanistic implications for the beneficial effects of the novel
Topics: Animals; Avoidance Learning; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Isoindoles; Learning Disabilities; Lurasidone Hydrochloride; Male; Maze Learning; Memory Disorders; Rats; Rats, Wistar; Reaction Time; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Serotonin Agents; Thiazoles; Time Factors | 2011 |
Independent contribution of temporal beta-amyloid deposition to memory decline in the pre-dementia phase of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Brain; Brain Mapping; Carbon Radioisotopes; Cognition Disorders; Female; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Memory Disorders; Middle Aged; Positron-Emission Tomography; Regression Analysis; Thiazoles | 2011 |
Face-name associative memory performance is related to amyloid burden in normal elderly.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Association Learning; Cerebral Cortex; Cognition; Face; Female; Humans; Male; Memory Disorders; Positron-Emission Tomography; Reference Values; Retention, Psychology; Thiazoles; Verbal Learning | 2011 |
Clinical course of patients with familial early-onset Alzheimer's disease potentially lacking senile plaques bearing the E693Δ mutation in amyloid precursor protein.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Aniline Compounds; Apolipoproteins E; Atrophy; Benzothiazoles; Brain; Cerebellar Ataxia; Cognition; Disease Progression; Female; Fluorodeoxyglucose F18; Gait Disorders, Neurologic; Humans; Magnetic Resonance Imaging; Memory Disorders; Middle Aged; Mutation; Neuropsychological Tests; Pedigree; Plaque, Amyloid; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles | 2011 |
Protective effect of meloxicam-loaded nanocapsules against amyloid-β peptide-induced damage in mice.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Avoidance Learning; Behavior, Animal; Body Weight; Brain; Catalase; Disease Models, Animal; Exploratory Behavior; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Learning Disabilities; Male; Maze Learning; Meloxicam; Memory Disorders; Mice; Nanocapsules; Peptide Fragments; Superoxide Dismutase; Thiazines; Thiazoles; Time Factors | 2012 |
A multifunctional peptide rescues memory deficits in Alzheimer's disease transgenic mice by inhibiting Aβ42-induced cytotoxicity and increasing microglial phagocytosis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Calcium; Cell Line, Tumor; Cell Survival; Cloning, Molecular; Coloring Agents; DNA; Enzyme-Linked Immunosorbent Assay; Humans; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; Microglia; Nitric Oxide; Peptide Fragments; Peptide Library; Peptides; Phagocytosis; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2012 |
Selective GABA(A) α5 positive allosteric modulators improve cognitive function in aged rats with memory impairment.
Topics: Aging; Allosteric Regulation; Animals; Carboxylic Acids; Cognition; Cognitive Dysfunction; GABA-A Receptor Agonists; Hippocampus; Infusions, Intraventricular; Injections, Intraperitoneal; Male; Memory; Memory Disorders; Molecular Targeted Therapy; Neurons; Nootropic Agents; Pyridazines; Rats; Rats, Long-Evans; Receptors, GABA-A; Specific Pathogen-Free Organisms; Synaptic Transmission; Thiazoles; Thiophenes | 2013 |
Rapid decline in episodic memory in healthy older adults with high amyloid-β.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Australia; Female; Humans; Male; Memory Disorders; Memory, Episodic; Neuropsychological Tests; Positron-Emission Tomography; Prospective Studies; Thiazoles | 2013 |
Associations between gonadotropins, testosterone and β amyloid in men at risk of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Apolipoproteins E; Cognitive Dysfunction; Cohort Studies; Gonadotropins; Humans; Linear Models; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Peptide Fragments; Positron-Emission Tomography; Psychiatric Status Rating Scales; Risk Factors; Statistics, Nonparametric; Testosterone; Thiazoles | 2014 |
Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Aniline Compounds; Cerebellar Cortex; Female; Humans; Image Processing, Computer-Assisted; Kinetics; Male; Memory Disorders; Middle Aged; Positron-Emission Tomography; Protein Binding; Radiography; Thiazoles | 2005 |
M1 receptors play a central role in modulating AD-like pathology in transgenic mice.
Topics: ADAM Proteins; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Antibodies, Monoclonal; Basigin; Behavior, Animal; Blotting, Western; Brain; Cell Count; Cytoskeletal Proteins; Dicyclomine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Escape Reaction; Gene Expression; GTP-Binding Proteins; Humans; Immunohistochemistry; Memory Disorders; Mice; Mice, Transgenic; Muscarinic Antagonists; Nuclear Proteins; Piperidines; Protein Kinase C; Reaction Time; Receptor, Muscarinic M1; Spatial Behavior; Spiro Compounds; tau Proteins; Thiazoles; Time Factors | 2006 |
Memory-related deficits following selective hippocampal expression of Swedish mutation amyloid precursor protein in the rat.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Benzothiazoles; Disease Models, Animal; Fluoresceins; Gene Expression; Genetic Vectors; Hippocampus; Humans; Immunohistochemistry; Male; Maze Learning; Memory Disorders; Mutation; Organic Chemicals; Peptide Fragments; Rats; Rats, Sprague-Dawley; Thiazoles | 2006 |
Lurasidone reverses MK-801-induced impairment of learning and memory in the Morris water maze and radial-arm maze tests in rats.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Isoindoles; Learning Disabilities; Lurasidone Hydrochloride; Male; Maze Learning; Memory Disorders; Rats; Rats, Wistar; Reaction Time; Swimming; Thiazoles | 2008 |
Neuromedin U inhibits inflammation-mediated memory impairment and neuronal cell-death in rodents.
Topics: Animals; Anti-Inflammatory Agents; Brain-Derived Neurotrophic Factor; Cell Death; Cells, Cultured; Data Interpretation, Statistical; DNA; Enzyme Inhibitors; Hippocampus; Inflammation; Lipopolysaccharides; Male; Memory Disorders; Memory, Short-Term; Mice; Neuroglia; Neurons; Neuropeptides; Proadifen; Psychomotor Performance; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles | 2008 |
ZTTA, a postproline cleaving enzyme inhibitor, improves cerebral ischemia-induced deficits in a three-panel runway task in rats.
Topics: Animals; Brain; Brain Ischemia; Conditioning, Operant; Male; Memory Disorders; Memory, Short-Term; Prolyl Oligopeptidases; Rats; Rats, Wistar; Serine Endopeptidases; Serine Proteinase Inhibitors; Thiazoles | 1996 |
Effect of ZTTA, a prolyl endopeptidase inhibitor, on memory impairment in a passive avoidance test of rats with basal forebrain lesions.
Topics: Animals; Avoidance Learning; Choline O-Acetyltransferase; Enzyme Inhibitors; Male; Memory Disorders; Neurons; Prolyl Oligopeptidases; Prosencephalon; Rats; Rats, Wistar; Serine Endopeptidases; Thiazoles | 1998 |
Facilitating effects of histamine on spatial memory deficit induced by scopolamine in rats.
Topics: Animals; Brain; Histamine; Histamine Agonists; Histamine Antagonists; Histidine; Injections, Intraventricular; Male; Maze Learning; Memory Disorders; Piperidines; Rats; Rats, Wistar; Scopolamine; Thiazoles | 2000 |
Alzheimer's disease. Arresting memory decline.
Topics: Alzheimer Disease; Animals; Carbolines; Cholinesterase Inhibitors; Humans; Memory Disorders; Nicotine; Piperidines; Rats; Receptors, Cholinergic; Receptors, GABA-A; Receptors, Nicotinic; Thiazoles | 1988 |