Page last updated: 2024-10-20

thiamine and Vascular Diseases

thiamine has been researched along with Vascular Diseases in 14 studies

thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.

Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.

Research Excerpts

ExcerptRelevanceReference
"Thirteen people with type 2 diabetes were given a heat-processed test meal with a high AGE content (HAGE; 15."2.72Benfotiamine prevents macro- and microvascular endothelial dysfunction and oxidative stress following a meal rich in advanced glycation end products in individuals with type 2 diabetes. ( Gawlowski, T; Götting, C; Horstmann, T; Kleesiek, K; Koschinsky, T; Mueller-Roesel, M; Negrean, M; Stirban, A; Stratmann, B; Tschoepe, D; Uribarri, J; Vlassara, H, 2006)
"One hundred and fifteen patients with type 2 diabetes with and without microalbuminuria or albuminuria and 39 healthy people were recruited."1.38Disturbance of B-vitamin status in people with type 2 diabetes in Indonesia--link to renal status, glycemic control and vascular inflammation. ( Adaikalakoteswari, A; Adam, JM; Kariadi, SH; Rabbani, N; Thornalley, PJ; Tjokroprawiro, A; Waspadji, S, 2012)
"Treatment with fenofibrate normalizes the altered lipid profile in diabetic rats, whereas benfotiamine treatment has no effect on lipid alteration in diabetic rats."1.35Ameliorative effect of combination of benfotiamine and fenofibrate in diabetes-induced vascular endothelial dysfunction and nephropathy in the rat. ( Balakumar, P; Chakkarwar, VA; Singh, M, 2009)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19909 (64.29)18.7374
1990's0 (0.00)18.2507
2000's4 (28.57)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balakumar, P1
Chakkarwar, VA1
Singh, M1
Adaikalakoteswari, A1
Rabbani, N2
Waspadji, S1
Tjokroprawiro, A1
Kariadi, SH1
Adam, JM1
Thornalley, PJ3
BODECKER, H1
SUCKOW, KL1
VALLE ZARATE, VC1
GORDON, DM1
GIROLAMI, M1
SMET, G1
Stirban, A1
Negrean, M1
Stratmann, B1
Gawlowski, T1
Horstmann, T1
Götting, C1
Kleesiek, K1
Mueller-Roesel, M1
Koschinsky, T1
Uribarri, J1
Vlassara, H1
Tschoepe, D1
Ahmed, N1
Babaei-Jadidi, R1
Al Ali, H1
Antonysunil, A1
Larkin, J1
Ahmed, A1
Rayman, G1
Bodmer, CW1
Naidoo, DP1
Rawat, R1
Dyer, RB1
Sadhabiriss, A1
Makgoba, MW1
Heynen, U1
Egerváry, O1
Haits, G1
Bódog, G1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of a Chronical Treatment With Benfotiamine in People With Type 2 Diabetes Mellitus on Pre- and Postprandial Endothelial Function, as Well as on the Function of the Autonomic Nervous System[NCT00446810]Phase 430 participants (Anticipated)Interventional2007-09-30Recruiting
A Double-Blind Clinical Trial of Benfotiamine Treatment in Diabetic Nephropathy[NCT00565318]Phase 486 participants (Anticipated)Interventional2007-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for thiamine and Vascular Diseases

ArticleYear
Advanced glycation endproducts: what is their relevance to diabetic complications?
    Diabetes, obesity & metabolism, 2007, Volume: 9, Issue:3

    Topics: Blood Glucose; Diabetes Complications; Glycation End Products, Advanced; Glycosylation; Humans; Hype

2007

Trials

1 trial available for thiamine and Vascular Diseases

ArticleYear
Benfotiamine prevents macro- and microvascular endothelial dysfunction and oxidative stress following a meal rich in advanced glycation end products in individuals with type 2 diabetes.
    Diabetes care, 2006, Volume: 29, Issue:9

    Topics: Adjuvants, Immunologic; Biomarkers; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; En

2006

Other Studies

12 other studies available for thiamine and Vascular Diseases

ArticleYear
Ameliorative effect of combination of benfotiamine and fenofibrate in diabetes-induced vascular endothelial dysfunction and nephropathy in the rat.
    Molecular and cellular biochemistry, 2009, Volume: 320, Issue:1-2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Chelating Agents; Diabetes Mellitu

2009
Disturbance of B-vitamin status in people with type 2 diabetes in Indonesia--link to renal status, glycemic control and vascular inflammation.
    Diabetes research and clinical practice, 2012, Volume: 95, Issue:3

    Topics: Albuminuria; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Indonesia; In

2012
[Cardiac & venous therapy of limited complications in organic circulatory disorders of lower extremities].
    Therapie der Gegenwart, 1957, Volume: 96, Issue:5

    Topics: Lower Extremity; Peripheral Vascular Diseases; Plant Extracts; Thiamine; Vascular Diseases; Veins

1957
[Physiological biocatalysts in therapy of blood vessel walls in venous and arterial circulatory disorders].
    Medizinische Klinik, 1957, Sep-20, Volume: 52, Issue:38

    Topics: Anticoagulants; Cardiovascular Diseases; Flavonoids; Humans; Peripheral Vascular Diseases; Thiamine;

1957
[Action of thiamine on the blood pyruvic acid in liver diseases and heart diseases].
    Revista clinica espanola, 1959, May-31, Volume: 73

    Topics: Heart Diseases; Humans; Liver Diseases; Pyruvates; Pyruvic Acid; Thiamine; Vascular Diseases

1959
SUDDEN LOSS OF VISION; DIAGNOSIS AND MANAGEMENT.
    Medical times, 1964, Volume: 92

    Topics: Adrenal Cortex Hormones; Angiomatosis; Anticoagulants; Aortic Diseases; Blindness; Carbonic Anhydras

1964
[ON 2 CASES OF ASCITES DUE TO HEPATIC CIRRHOSIS IN SUBJECTS OPERATED ON BY SPLENECTOMY AND PRESENTING PORTA OBLITERATION--CLINICAL RECOVERY FOLLOWING TREATMENT WITH HIGH DOSES OF TESTOSTERONE AND VITAMIN B 1].
    Rassegna clinico-scientifica, 1964, Volume: 40

    Topics: Ascites; Blood Protein Electrophoresis; Folic Acid; Humans; Liver Cirrhosis; Portal System; Splenect

1964
[ATHEROSCLEROSIS OF THE LOWER EXTREMITIES].
    Belgisch tijdschrift voor geneeskunde, 1964, Nov-01, Volume: 20

    Topics: Angiography; Arteriosclerosis Obliterans; Atherosclerosis; Barbiturates; Diagnosis, Differential; Dr

1964
High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease.
    Diabetologia, 2007, Volume: 50, Issue:10

    Topics: Albuminuria; Biomarkers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies

2007
Cardiac beriberi. A report of 4 cases.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1987, Aug-15, Volume: 72, Issue:4

    Topics: Adult; Beriberi; Blood Pressure; Electrocardiography; Heart Diseases; Humans; Hypotension; Male; Mid

1987
[Intracutaneous hormone therapy activates local blood flow].
    Zeitschrift fur Allgemeinmedizin, 1970, Jul-20, Volume: 46, Issue:20

    Topics: Amputation Stumps; Esters; Gonadal Steroid Hormones; Humans; Ointments; Pain; Phytotherapy; Plant Ex

1970
[Anterior tibial syndrome].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1968, Volume: 20, Issue:9

    Topics: Adolescent; Adult; Arteries; Diagnosis, Differential; Edema; Electromyography; Humans; Ischemia; Leg

1968