thiamine has been researched along with Pain in 51 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Nonetheless, pain intensity reduction is achieved with 50% of the minimum required gabapentin dose alone (800 to 1600 mg/d) in classic NDD trials." | 9.22 | Clinical Trial Assessing the Efficacy of Gabapentin Plus B Complex (B1/B12) versus Pregabalin for Treating Painful Diabetic Neuropathy. ( Aguilar Navarro, S; Mimenza Alvarado, A, 2016) |
| "Tenderness in the limb muscles has been reported anecdotally in patients with beriberi neuropathy, but clinical effects of thiamine deficiency on skeletal muscle have received little attention." | 7.73 | Myopathy in thiamine deficiency: analysis of a case. ( Hattori, N; Iijima, M; Inukai, A; Koike, H; Mori, K; Sobue, G; Watanabe, H, 2006) |
| "To determine the clinicopathologic features and pathogenesis of alcoholic polyneuropathy associated with pain in patients with normal thiamine status, particularly in comparison to beriberi neuropathy." | 7.71 | Painful alcoholic polyneuropathy with predominant small-fiber loss and normal thiamine status. ( Hattori, N; Hirayama, M; Ito, H; Koike, H; Misu, K; Mori, K; Sobue, G, 2001) |
| " Nonetheless, pain intensity reduction is achieved with 50% of the minimum required gabapentin dose alone (800 to 1600 mg/d) in classic NDD trials." | 5.22 | Clinical Trial Assessing the Efficacy of Gabapentin Plus B Complex (B1/B12) versus Pregabalin for Treating Painful Diabetic Neuropathy. ( Aguilar Navarro, S; Mimenza Alvarado, A, 2016) |
| "Forty-five diabetes patients with painful peripheral polyneuropathy were enrolled in a 3-month observational study comparing the therapeutic efficacy of Milgamma tablets (50 mg benfothiamine and 0." | 5.08 | Therapeutic efficacy of "Milgamma" in patients with painful diabetic neuropathy. ( Mincheva, L; Mitkov, M; Pavlova, M; Simeonov, S; Troev, D, 1997) |
| "Tenderness in the limb muscles has been reported anecdotally in patients with beriberi neuropathy, but clinical effects of thiamine deficiency on skeletal muscle have received little attention." | 3.73 | Myopathy in thiamine deficiency: analysis of a case. ( Hattori, N; Iijima, M; Inukai, A; Koike, H; Mori, K; Sobue, G; Watanabe, H, 2006) |
| "To determine the clinicopathologic features and pathogenesis of alcoholic polyneuropathy associated with pain in patients with normal thiamine status, particularly in comparison to beriberi neuropathy." | 3.71 | Painful alcoholic polyneuropathy with predominant small-fiber loss and normal thiamine status. ( Hattori, N; Hirayama, M; Ito, H; Koike, H; Misu, K; Mori, K; Sobue, G, 2001) |
| "Hansen disease is an infectious chronic disease with various clinical manifestations." | 1.48 | Rheumatoid arthritis-like features in Hansen disease: A case report. ( Gao, LN; Wang, Y; Zhong, B, 2018) |
| "Cotreatment of thiamine with L-NAME and MB significantly increased the L-NAME-induced antinociception (53." | 1.31 | Role of guanylyl cyclase activation via thiamine in suppressing chemically-induced writhing in mouse. ( Abacioğlu, N; Cakici, I; Demir, S; Kanzik, I; Tunçtan, B, 2000) |
| "We reported a 3-year-old girl with myoclonus epilepsy associated with ragged-red fibers (MERRF) who was afflicted with recurrent pain attacks and allodynia on the right side of the body." | 1.30 | Recurrent pain attacks in a 3-year-old patient with myoclonus epilepsy associated with ragged-red fibers (MERRF): a single-photon emission computed tomographic (SPECT) and electrophysiological study. ( Goto, Y; Matsuda, H; Nonaka, I; Osari, S; Ozawa, M; Tanaka, S; Yamanouchi, H, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (70.59) | 18.7374 |
| 1990's | 4 (7.84) | 18.2507 |
| 2000's | 7 (13.73) | 29.6817 |
| 2010's | 2 (3.92) | 24.3611 |
| 2020's | 2 (3.92) | 2.80 |
| Authors | Studies |
|---|---|
| Coary, R | 1 |
| Skerritt, CJ | 1 |
| Nakamura, K | 1 |
| Abe, N | 1 |
| Horita, T | 1 |
| Gao, LN | 1 |
| Zhong, B | 1 |
| Wang, Y | 1 |
| Mimenza Alvarado, A | 1 |
| Aguilar Navarro, S | 1 |
| SULIMOVSKAYA, NA | 1 |
| GLUCK, W | 1 |
| LEOPARDI, G | 1 |
| STERN, EL | 1 |
| SZIRMAI, E | 1 |
| STOERGER, R | 1 |
| MENGI, E | 1 |
| REINHARDT, G | 1 |
| WADA, M | 1 |
| HUEBER, EF | 1 |
| CAMPANELLA, G | 1 |
| HORN, B | 1 |
| GYONGYOSI, F | 1 |
| Haupt, E | 1 |
| Ledermann, H | 1 |
| Köpcke, W | 1 |
| Koike, H | 2 |
| Watanabe, H | 1 |
| Inukai, A | 1 |
| Iijima, M | 1 |
| Mori, K | 2 |
| Hattori, N | 2 |
| Sobue, G | 2 |
| Medvedeva, LA | 1 |
| Gnezdilov, AV | 1 |
| Zagorul'ko, OI | 1 |
| Syrovegin, AV | 1 |
| Samoĭlova, NV | 1 |
| Slashchuk, IuI | 1 |
| Małecka, SA | 1 |
| Poprawski, K | 1 |
| Bilski, B | 1 |
| Kakishita, M | 1 |
| Kawanishi, H | 1 |
| Uemura, J | 1 |
| Murayama, F | 1 |
| Uchino, H | 1 |
| Nowak, S | 1 |
| Bagnoli, P | 1 |
| Tanaka, S | 1 |
| Osari, S | 1 |
| Ozawa, M | 1 |
| Yamanouchi, H | 1 |
| Goto, Y | 1 |
| Matsuda, H | 1 |
| Nonaka, I | 1 |
| Simeonov, S | 1 |
| Pavlova, M | 1 |
| Mitkov, M | 1 |
| Mincheva, L | 1 |
| Troev, D | 1 |
| Winkler, G | 1 |
| Pál, B | 1 |
| Nagybéganyi, E | 1 |
| Ory, I | 1 |
| Porochnavec, M | 1 |
| Kempler, P | 1 |
| Abacioğlu, N | 1 |
| Demir, S | 1 |
| Cakici, I | 1 |
| Tunçtan, B | 1 |
| Kanzik, I | 1 |
| Misu, K | 1 |
| Ito, H | 1 |
| Hirayama, M | 1 |
| França, DS | 1 |
| Souza, AL | 1 |
| Almeida, KR | 1 |
| Dolabella, SS | 1 |
| Martinelli, C | 1 |
| Coelho, MM | 1 |
| Navarro Martínez, DP | 1 |
| Shneĭder, AB | 1 |
| Pohl, J | 1 |
| Mewe, R | 1 |
| König, HJ | 1 |
| Fu, QG | 1 |
| Carstens, E | 1 |
| Stelzer, B | 1 |
| Zimmermann, M | 1 |
| Hanck, A | 1 |
| Weiser, H | 1 |
| Mocavero, G | 1 |
| Riemann, D | 1 |
| Huss, V | 1 |
| Makiyama, T | 1 |
| Kamidani, M | 1 |
| Senda, Y | 1 |
| Stork, W | 1 |
| Fujihira, E | 1 |
| Tarumoto, Y | 1 |
| Ajioka, M | 1 |
| Mori, T | 1 |
| Nakazawa, M | 1 |
| Martens, HL | 1 |
| Omori, K | 1 |
| Sasaki, J | 1 |
| Suzuki, M | 1 |
| Otsuki, K | 1 |
| Yamamoto, H | 1 |
| Martins, HT | 1 |
| Faldini, A | 1 |
| Marchetti, N | 1 |
| Zinkernagel, R | 1 |
| Schneider, H | 1 |
| Heynen, U | 1 |
| Stronski, E | 1 |
| Nose, T | 1 |
| Yasuda, K | 1 |
| Nakama, M | 1 |
| Adachi, S | 1 |
| Kowa, Y | 1 |
| Yamada, S | 1 |
| Ishikawa, S | 1 |
| Chibata, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicenter, Randomized, Open-label, Parallel Group, Phase IV Study to Compare the Efficacy and Safety of Gabapentin/B-complex Versus Pregabalin in the Management of Diabetic Peripheral Neuropathic Pain[NCT01364298] | Phase 4 | 353 participants (Actual) | Interventional | 2011-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
An adverse event (AE) is defined as any untoward medical occurrence in the form of signs, symptoms, abnormal laboratory findings, or diseases that emerges or worsens relative to Baseline during a clinical study with an investigational medicinal product (IMP), regardless of causal relationship and even if no IMP has been administered. (NCT01364298)
Timeframe: Day 7 up to Day 84 (+7 days)
| Intervention | participants (Number) |
|---|---|
| Gabapentin/B-complex | 80 |
| Pregabalin | 93 |
"POMS is a rating scale, which comprises of 65 items that are evaluated in a 0-4 scale, where 0 means not at all and 4 extremely. The scores for the 65 items are added in various combinations to throw six validated factors which are used to calculate total POMS score: (tension-anxiety) + (depression-dejection) + (anger-hostility)+ (fatigue-Inertia) + (confusion-bewilderment) - (vigor-activity). Score range (-40 to 192). Score -40 denotes the best score and score 192 denotes the worst score." (NCT01364298)
Timeframe: Day 84 (Week 12)
| Intervention | units on a scale (Mean) |
|---|---|
| Gabapentin/B-complex | 1.3 |
| Pregabalin | 3.4 |
An average NPIS pain score (daily average records of the past seven days) was evaluated. Numeric pain intensity scale (NPIS) is a 11-point scale, with 0 representing no pain and 10 representing the worst possible pain. The participants were asked to mark the number that best represents the current level of pain they have experienced during the previous 24 hours. Change from baseline data has been calculated as value at baseline minus value at Day 84. (NCT01364298)
Timeframe: Baseline and Day 84 (Week 12)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (n=147, 123) | Change at Day 84 (n=146, 122) | |
| Gabapentin/B-complex | 6.7 | 3.905 |
| Pregabalin | 6.8 | 4.260 |
The LANSS scale score is 7-item pain scale that consists of grouped sensory description and sensory examination with simple scoring system. Evaluations in two main areas: pain and sensorial exploration. The first 5 questions asks for presence of unpleasant skin sensations (pricking, tingling, pins and needles), appearance of skin (mottled, red, or pink), increased sensitivity of skin to touch, sudden bursts of electric shock sensations, and hot or burning skin sensations. Last 2 questions involve sensory testing for the presence of allodynia and altered pinprick threshold. Different numbers of points, relative to their significance to neuropathic pain, are given to positive answers for maximum of 24 points. A score less than 12 makes unlikely that participant's symptoms are neuropathic in nature, whereas score more than 12 make neuropathic mechanisms likely to be contributing to participant's pain. Change from baseline data has been calculated as value at baseline minus value at Day 84. (NCT01364298)
Timeframe: Baseline and Day 84 (Week 12)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline (n=147, 123) | Change at Day 84 (n=146, 122) | |
| Gabapentin/B-complex | 16.2 | 8.082 |
| Pregabalin | 15.8 | 6.967 |
VAS is used to rate the pain as per 10 centimeter (cm) line. The pain intensity score ranges from '0=no pain' to '10=worst possible pain'. Change from baseline data has been calculated as value at baseline minus value at Day 84. (NCT01364298)
Timeframe: Baseline and Day 84 (Week 12)
| Intervention | centimeter (Mean) | |
|---|---|---|
| Baseline (n=147, 123) | Change at Day 84 (n=146, 122) | |
| Gabapentin/B-complex | 7.0 | 4.182 |
| Pregabalin | 7.1 | 4.529 |
CGIC is an assessment that the physician performs to assess the participant's global change in health condition from start of the study on a 7-point scale (1 = extremely improved, 2 = much improved, 3 = minimally improved, 4 = no change, 5 = minimally worse 6 = much worse, 7 = extremely worse). (NCT01364298)
Timeframe: Baseline and Day 84 (Week 12)
| Intervention | participants (Number) | ||
|---|---|---|---|
| Health: extremely improved | Health: much improved | Health: minimally improved | |
| Gabapentin/B-complex | 55 | 79 | 11 |
| Pregabalin | 47 | 69 | 6 |
GIPC is an assessment that the participant's global change in health condition from start of the study on a 7-point scale (1 = extremely improved, 2 = much improved, 3 = minimally improved, 4 = no change, 5 = minimally worse 6 = much worse, 7 = extremely worse). (NCT01364298)
Timeframe: Baseline and Day 84 (Week 12)
| Intervention | participants (Number) | ||
|---|---|---|---|
| Health: extremely improved | Health: much improved | Health: minimally improved | |
| Gabapentin/B-complex | 62 | 73 | 10 |
| Pregabalin | 47 | 65 | 10 |
NPIS is a 11-point scale, with 0 representing no pain and 10 representing the worst possible pain. The participants were asked to mark the number that best represents the current level of pain they have experienced during the previous 24 hours. (NCT01364298)
Timeframe: Baseline and Day 84 (Week 12)
| Intervention | percentage of participants (Number) | |
|---|---|---|
| At least 30% improvement | At least 50% improvement | |
| Gabapentin/B-complex | 76.9 | 66.0 |
| Pregabalin | 85.4 | 72.4 |
Sleep evaluation was performed by assessing number of participants who fell asleep in a particular pre-specified range of time duration, that is, 0-15 minutes, 16-30 minutes, 31-45 minutes, 46-60 minutes and greater than 60 minutes at Day 84 (Week 12). (NCT01364298)
Timeframe: Day 84 (Week 12)
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| 0 to 15 minutes | 16 to 30 minutes | 31 to 45 minutes | 46 to 60 minutes | Greater than 60 minutes | |
| Gabapentin/B-complex | 85 | 33 | 13 | 8 | 8 |
| Pregabalin | 72 | 33 | 12 | 4 | 2 |
1 review available for thiamine and Pain
| Article | Year |
|---|---|
[Prophylactic and therapeutic application of thiamine (vitamin B1)--a new point of view].
Topics: Animals; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus; Diabetic Angiopathies; Humans; Pai | 2006 |
7 trials available for thiamine and Pain
| Article | Year |
|---|---|
Clinical Trial Assessing the Efficacy of Gabapentin Plus B Complex (B1/B12) versus Pregabalin for Treating Painful Diabetic Neuropathy.
Topics: Adolescent; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Combinatio | 2016 |
Benfotiamine in the treatment of diabetic polyneuropathy--a three-week randomized, controlled pilot study (BEDIP study).
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type | 2005 |
[Neurometabolic therapy of diabetic neuropathy].
Topics: Adjuvants, Immunologic; Analgesics, Non-Narcotic; Antioxidants; Blood Glucose; Carbamazepine; Diabet | 2006 |
Therapeutic efficacy of "Milgamma" in patients with painful diabetic neuropathy.
Topics: Adult; Aged; Diabetic Neuropathies; Female; Humans; Male; Middle Aged; Pain; Thiamine; Vitamin B 12; | 1997 |
Effectiveness of different benfotiamine dosage regimens in the treatment of painful diabetic neuropathy.
Topics: Adult; Aged; Blood Glucose; Chelating Agents; Cholesterol; Diabetic Neuropathies; Female; Glycated H | 1999 |
[Clinical significance of vitamin B1, B6, B12 in pain therapy. Results of a scientific meeting of experts 5-7 November 1987 in Pommersfelden].
Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Pain; Pyridoxine; Thiamine; Vita | 1988 |
[Evaluation of the effecs of Alinaminf tablets on pain in orthopedic patients--with reference to the analysis of the results by sequential trial].
Topics: Adolescent; Adult; Aged; Analgesics; Back Pain; Bone Diseases; Clinical Trials as Topic; Female; Hum | 1967 |
43 other studies available for thiamine and Pain
| Article | Year |
|---|---|
Response to: Moorthy, Aneurin,
Topics: Analgesics; Anesthesia, Conduction; Femoral Nerve; Fractures, Bone; Humans; Nerve Block; Pain; Pain, | 2023 |
Thiamine Deficiency Manifesting Acute Right Hypochondrial Pain with Lactic Acidosis.
Topics: Acidosis, Lactic; Humans; Pain; Thiamine; Thiamine Deficiency | 2023 |
Rheumatoid arthritis-like features in Hansen disease: A case report.
Topics: Arthritis, Rheumatoid; Diagnosis, Differential; Female; Humans; Joints; Leprosy; Middle Aged; Pain; | 2018 |
[The changes of ketonemia in pains and after injection of vitamin B1].
Topics: Blood; Humans; Injections; Ketone Bodies; Ketosis; Pain; Thiamine | 1945 |
[The use of vitamin B1 in dentistry with special reference to postextraction pain].
Topics: Dentistry; Humans; Pain; Thiamine; Tooth Extraction | 1953 |
[Effects of an antihistaminic combined with the monophosphoric ester of thiamine on a..amnestic local anesthesia].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Local; Cornea; Histamine H1 Antagonists | 1955 |
Detoxification and augmented anesthesia of procaine by thiamin (vitamin B1).
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesiology; Pain; Procaine; Thiamine | 1956 |
[Thiamine (vitamin B 1) and its effects on the uterine musculature and on the pain during delivery (preliminary report)].
Topics: Delivery, Obstetric; Female; Humans; Labor, Obstetric; Myometrium; Pain; Pregnancy; Thiamine; Vitami | 1961 |
[THE CONTROL OF PAIN STATES IN NEUROLOGICAL DISEASES BY NEUROBION].
Topics: Herpes Zoster; Humans; Nervous System Diseases; Neuralgia; Neuritis; Pain; Phantom Limb; Pyridoxine; | 1963 |
[DIAGNOSIS OF DIABETIC NEUROPATHIES. CLINICAL ASPECTS].
Topics: Autonomic Nervous System Diseases; Diabetic Neuropathies; Fatigue; Humans; Hypoglycemic Agents; Insu | 1964 |
[ON THE USE OF THIANEURONE, A NEW ORAL VITAMIN B-1 PREPARATION, FOR THE THERAPY OF NEURITIC PAINS].
Topics: Anemia; Arthritis; Arthritis, Rheumatoid; Back Pain; Beriberi; Cardiovascular Diseases; Diabetes Mel | 1964 |
[CONSIDERATIONS ON ANTIALGIC EFFECTS OBTAINED IN NEUROLOGIC PATIENTS WITH THE PHARMACOLOGIC ASSOCIATION: DIISOPROPYLAMMONIUM DICHLOROETHANOATE, VITAMIN B 1, VITAMIN B 12].
Topics: Folic Acid; Humans; Nervous System Diseases; Pain; Quaternary Ammonium Compounds; Thiamine; Vitamin | 1965 |
[Analgesia in obstetrics with special reference to dolamid (Depridol) plus vitamin B1].
Topics: Analgesia; Analgesics; Female; Humans; Labor, Obstetric; Obstetrics; Pain; Pregnancy; Thiamine | 1951 |
Myopathy in thiamine deficiency: analysis of a case.
Topics: Adult; Biomarkers; Cardiomegaly; Creatine Kinase; Diet; Edema; Female; Fructose-Bisphosphate Aldolas | 2006 |
[Clinical experience with VMP-908 for pain due to cancer].
Topics: Adult; Analgesics; Female; Humans; Male; Middle Aged; Neoplasms; Pain; Thiamine | 1966 |
[Analgesic effect of Alinamin F on neuralgia-like pain in the terminal stage of cervical cancer].
Topics: Aged; Antibiotics, Antineoplastic; Cobalt Isotopes; Female; Humans; Middle Aged; Pain; Thiamine; Ute | 1966 |
[Clinical observations on therapeutic application of dithiopropylothiamine].
Topics: Diabetic Neuropathies; Humans; Neuralgia; Pain; Thiamine | 1967 |
[Statistical study on operative and postoperative management using high-unit injection of thiamine tetrahydroflurfril disulphite (TTFD). IV. Postoperative complaints].
Topics: Adolescent; Adult; Anesthesia, General; Female; Humans; Male; Middle Aged; Pain; Postoperative Compl | 1967 |
[Mastodynias].
Topics: Breast Diseases; Chymotrypsin; Female; Humans; Methandriol; Methyltestosterone; Pain; Parathyroid Ho | 1980 |
Recurrent pain attacks in a 3-year-old patient with myoclonus epilepsy associated with ragged-red fibers (MERRF): a single-photon emission computed tomographic (SPECT) and electrophysiological study.
Topics: Child, Preschool; Cytochrome c Group; Epilepsies, Myoclonic; Evoked Potentials, Somatosensory; Femal | 1997 |
Role of guanylyl cyclase activation via thiamine in suppressing chemically-induced writhing in mouse.
Topics: Animals; Arginine; Benzoquinones; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibi | 2000 |
Painful alcoholic polyneuropathy with predominant small-fiber loss and normal thiamine status.
Topics: Adult; Aged; Alcoholic Neuropathy; Humans; Male; Middle Aged; Nerve Fibers, Myelinated; Neural Condu | 2001 |
B vitamins induce an antinociceptive effect in the acetic acid and formaldehyde models of nociception in mice.
Topics: Acetic Acid; Animals; Constriction; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; | 2001 |
[Treatment of painful diseases by analgesic LA-675 in the industrial medicine].
Topics: Aminopyrine; Analgesics; Codeine; Drug Combinations; Drug Evaluation; Female; Headache; Menstruation | 1975 |
[The importance of Vitamin B1, B6, B12 in the treatment of pain. New pharmacologic and clinical findings. Wiesbaden, 26 May 1989. Proceedings].
Topics: Animals; Humans; Pain; Pyridoxine; Thiamine; Vitamin B 12 | 1990 |
[Stereometric evaluation of the myocardial cardiomyocyte-capillary ratio in emotional and pain-induced stress after administration of thiamine and nicotinamide].
Topics: Animals; Capillaries; Capillary Permeability; Coronary Circulation; Injections, Subcutaneous; Male; | 1989 |
[Reversible and irreversible lesions of the conus medullaris and cauda equina after lumber paravertebral infiltration injection].
Topics: Adult; Aminopyrine; Anesthetics, Local; Anti-Inflammatory Agents; Back Pain; Cauda Equina; Dexametha | 1985 |
B vitamins suppress spinal dorsal horn nociceptive neurons in the cat.
Topics: Animals; Cats; Dose-Response Relationship, Drug; Hot Temperature; Injections, Spinal; Nociceptors; P | 1988 |
Analgesic and anti-inflammatory properties of vitamins.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Ascorbic Acid; Dose-Response Relationship, Drug; Huma | 1985 |
[Role of the pain specialist in the treatment of pancreatic pain].
Topics: Adult; Antidepressive Agents; Buprenorphine; Chronic Disease; Humans; Male; Middle Aged; Morphine; P | 1985 |
[Clinical aspects and therapy of neuralgia and vertebrogenic pains in the clinic and practice of an otorhinolaryngologist].
Topics: Adult; Aged; Analgesics; Female; Humans; Male; Middle Aged; Neuralgia; Otorhinolaryngologic Diseases | 1971 |
[Combined drug therapy in highly acute attacks of pain in the course of rheumatic diseases].
Topics: Acute Disease; Aminopyrine; Arthritis, Rheumatoid; Dexamethasone; Drug Combinations; Female; Humans; | 1974 |
[Experiences with Ambene in gynecological practice].
Topics: Adolescent; Adult; Aluminum; Dexamethasone; Drug Combinations; Female; Genital Diseases, Female; Gly | 1972 |
[Analgesic effect of o-isobutyrylthiamine disulfide on experimentally induced pain].
Topics: Analgesics; Animals; Butyrates; Disulfides; Dogs; Female; Male; Pain; Rats; Thiamine | 1973 |
[Experiences with a new neuro analgetic preparation].
Topics: Adult; Aged; Antipyrine; Dosage Forms; Humans; Middle Aged; Pain; Thiamine | 1972 |
[Results in use of Rheumatol-D for mandibular joint diseases].
Topics: Adolescent; Adult; Ascorbic Acid; Dexamethasone; Female; Humans; Joint Diseases; Male; Middle Aged; | 1967 |
[Clinical study of a new analgesic. Preparation 80260 (Nevralgan (R))].
Topics: Adolescent; Adult; Aged; Aminopyrine; Analgesics; Female; Humans; Male; Middle Aged; Pain; Thiamine | 1965 |
[Clinical trial of a new synthetic product: o-ethoxybenzylhydrazone of diethanolamine pyruvate associated with vitamins B 1, B 6 and B 12 and dichloroethanoate of diisopropylammonium in the treatment of rheumatic and neuritic pain syndromes].
Topics: Amino Alcohols; Analgesics; Anti-Inflammatory Agents; Humans; Neuritis; Pain; Pyridoxine; Pyruvates; | 1970 |
[Distal types of plexus brachialis neuritis].
Topics: Aged; Analgesics; Brachial Plexus; Cortisone; Electric Stimulation Therapy; Electromyography; Female | 1970 |
[Causal therapy of pain states in neurologic diseases].
Topics: Analgesics; Antipyrine; Humans; Methylamines; Nervous System Diseases; Pain; Pyridoxine; Sulfonic Ac | 1970 |
[Intracutaneous hormone therapy activates local blood flow].
Topics: Amputation Stumps; Esters; Gonadal Steroid Hormones; Humans; Ointments; Pain; Phytotherapy; Plant Ex | 1970 |
[Experiences in general practice with a new neural analgesic preparation].
Topics: Adult; Aged; Drug Synergism; Female; Humans; Male; Middle Aged; Pain; Pyrazoles; Thiamine | 1971 |
Biological and pharmacological properties of thiamine monophosphate disulfide.
Topics: Animals; Anura; Blood Pressure; Coronary Vessels; Dogs; Fatigue; In Vitro Techniques; Intestine, Sma | 1966 |