Page last updated: 2024-10-20

thiamine and Nervous System Disorders

thiamine has been researched along with Nervous System Disorders in 54 studies

thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.

Research Excerpts

ExcerptRelevanceReference
"The 3 cases demonstrated the rapidity of the reversal of severe thiamine deficiency, achieved by appropriate replacement in different hospitalized patients."7.81Rapid reversal of severe lactic acidosis after thiamine administration in critically ill adults: a report of 3 cases. ( Abramo, A; Forfori, F; Giacalone, M; Giunta, F; Iacconi, P; Martinelli, R; Pavoni, V; Rubino, A, 2015)
"The 3 cases demonstrated the rapidity of the reversal of severe thiamine deficiency, achieved by appropriate replacement in different hospitalized patients."3.81Rapid reversal of severe lactic acidosis after thiamine administration in critically ill adults: a report of 3 cases. ( Abramo, A; Forfori, F; Giacalone, M; Giunta, F; Iacconi, P; Martinelli, R; Pavoni, V; Rubino, A, 2015)
"Two girls with DIDMOAD syndrome are presented."1.29Growth hormone deficiency and empty sella in DIDMOAD syndrome: an endocrine study. ( Asfour, M; Bappal, B; Darwish, A; Rajab, A; Soliman, AT, 1995)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199033 (61.11)18.7374
1990's7 (12.96)18.2507
2000's6 (11.11)29.6817
2010's5 (9.26)24.3611
2020's3 (5.56)2.80

Authors

AuthorsStudies
Calderón-Ospina, CA1
Nava-Mesa, MO1
Iimura, Y1
Kurokawa, T1
Nojima, M1
Kanemoto, Y1
Yazawa, K1
Tsurita, G1
Kuroda, S1
Chevalier, K1
Stammler, R1
Paulet, R1
Vernau, K1
Napoli, E1
Wong, S1
Ross-Inta, C1
Cameron, J1
Bannasch, D1
Bollen, A1
Dickinson, P1
Giulivi, C1
Banka, S1
de Goede, C1
Yue, WW1
Morris, AA1
von Bremen, B1
Chandler, KE1
Feichtinger, RG1
Hart, C1
Khan, N1
Lunzer, V1
Mataković, L1
Marquardt, T1
Makowski, C1
Prokisch, H1
Debus, O1
Nosaka, K1
Sonwalkar, H1
Zimmermann, FA1
Sperl, W1
Mayr, JA1
Giacalone, M1
Martinelli, R1
Abramo, A1
Rubino, A1
Pavoni, V1
Iacconi, P1
Giunta, F1
Forfori, F1
Tonduti, D1
Chiapparini, L1
Moroni, I1
Ardissone, A1
Zorzi, G1
Zibordi, F1
Raspante, S1
Panteghini, C1
Garavaglia, B1
Nardocci, N1
Barnerias, C1
Saudubray, JM1
Touati, G1
De Lonlay, P1
Dulac, O1
Ponsot, G1
Marsac, C1
Brivet, M1
Desguerre, I1
AMICI, R1
MANNELL, WA1
ROSSITER, RJ1
SHUMAN, CR1
GILPIN, SF1
PRIESSNITZ, O2
BRAUER, WG1
COUSIN, JP1
PERON, N1
PRITZSCHE, G1
STOERGER, R1
MENGI, E1
REINHARDT, G1
MIZUTAME, A1
DEGUCHI, T1
KATSUNUMA, H1
SATO, S1
OKADA, M1
YAMAMOTO, T1
SUZUKI, M1
CAMPANELLA, G1
KALM, H1
LUCKNER, H1
MAGUN, R1
McIntosh, C1
Chick, J1
Hillbom, M1
Başoğlu, M1
Yetimalar, Y1
Gürgör, N1
Büyükçatalbaş, S1
Kurt, T1
Seçil, Y1
Yeniocak, A1
Langohr, HD1
Petruch, F1
Schroth, G1
Soliman, AT1
Bappal, B1
Darwish, A1
Rajab, A1
Asfour, M1
Domenech, J1
Formenty, P1
Djoenaidi, W1
Notermans, SL1
Verbeek, AL1
Bowden, S1
Bardenhagen, F1
Ambrose, M1
Whelan, G1
Lee, BY1
Thurmon, TF1
Yoshino, M1
Aoki, K1
Akeda, H1
Hashimoto, K1
Ikeda, T1
Inoue, F1
Ito, M2
Kawamura, M1
Kohno, Y1
Koga, Y1
Kuroda, Y2
Maesaka, H1
Murakamisoda, H1
Sugiyama, N1
Suzuki, Y1
Yano, S1
Yoshioka, A1
Hinze-Selch, D1
Weber, MM1
Zimmermann, U1
Pollmächer, T1
Naito, E1
Bowden, SC1
Crews, FT1
Bates, ME1
Fals-Stewart, W1
Ambrose, ML1
Reilly, TM1
Read, DJ1
Dreyfus, PM2
Iwashima, A1
Nose, Y1
Katsura, E1
Oiso, T1
Itokawa, Y1
Jubb, TF1
Garcia Roman, A1
Moyano Salvago, MR1
Soler Rodriguez, F1
Infante Miranda, F1
Alston, TA1
Umoh, IB1
Ogunkoya, FO1
Maduagwu, EN1
Oke, OL1
Kanig, K1
McVicar, M1
Gauthier, B1
Goodman, CT1
Pluvinage, R1
Victor, M1
Mussini, C1
Neviani, V1
Rindi, G1
Sciorelli, G1
Schneider, H1
Koake, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of the Nutritional Support System (NSS) on Neuromotor Alterations in Patients With Cerebral Palsy[NCT05648422]144 participants (Anticipated)Interventional2023-01-16Recruiting
Double Blind Evaluation of Gamma-aminobutyric Acid Tartarate 100 mg, Glutamic Acid 100 mg, Dibasic Calcium Phosphate 50 mg, Thiamine Nitrate 25 mg, Pyridoxine Chloride 10 mg and Cyanocobalamin 5 mcg Versus Ginger for Vertigo-kinetosis[NCT05221892]Phase 4334 participants (Actual)Interventional2021-11-22Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

10 reviews available for thiamine and Nervous System Disorders

ArticleYear
B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin.
    CNS neuroscience & therapeutics, 2020, Volume: 26, Issue:1

    Topics: Animals; Central Nervous System; Humans; Nervous System Diseases; Nervous System Physiological Pheno

2020
B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin.
    CNS neuroscience & therapeutics, 2020, Volume: 26, Issue:1

    Topics: Animals; Central Nervous System; Humans; Nervous System Diseases; Nervous System Physiological Pheno

2020
B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin.
    CNS neuroscience & therapeutics, 2020, Volume: 26, Issue:1

    Topics: Animals; Central Nervous System; Humans; Nervous System Diseases; Nervous System Physiological Pheno

2020
B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin.
    CNS neuroscience & therapeutics, 2020, Volume: 26, Issue:1

    Topics: Animals; Central Nervous System; Humans; Nervous System Diseases; Nervous System Physiological Pheno

2020
Neurological Disorders Associated with Striatal Lesions: Classification and Diagnostic Approach.
    Current neurology and neuroscience reports, 2016, Volume: 16, Issue:6

    Topics: Biological Transport; Humans; Infections; Movement Disorders; Necrosis; Nervous System Diseases; Thi

2016
Alcohol and the nervous system.
    Journal of neurology, neurosurgery, and psychiatry, 2004, Volume: 75 Suppl 3

    Topics: Alcohol Drinking; Alcohol Withdrawal Seizures; Alcoholic Intoxication; Alcoholism; Central Nervous S

2004
[Thiamine treatment in psychiatry and neurology].
    Fortschritte der Neurologie-Psychiatrie, 2000, Volume: 68, Issue:3

    Topics: Humans; Mental Disorders; Nervous System Diseases; Psychoses, Alcoholic; Thiamine; Thiamine Deficien

2000
[Vitamin dependency syndrome].
    Ryoikibetsu shokogun shirizu, 2000, Issue:29 Pt 4

    Topics: Biotin; Diagnosis, Differential; Folic Acid; Humans; Metabolism, Inborn Errors; Nervous System Disea

2000
Neurotoxicity and neurocognitive impairments with alcohol and drug-use disorders: potential roles in addiction and recovery.
    Alcoholism, clinical and experimental research, 2001, Volume: 25, Issue:2

    Topics: Alcoholism; Animals; Brain; Cognition Disorders; Humans; Nervous System Diseases; Substance-Related

2001
The aetiology of the sudden infant death syndrome: current ideas on breathing and sleep and possible links to deranged thiamine neurochemistry.
    Australian and New Zealand journal of medicine, 1978, Volume: 8, Issue:3

    Topics: Animals; Apnea; Asphyxia; Australia; Cattle; Female; Humans; Infant; Male; Nervous System Diseases;

1978
Thiamine and the nervous system: an overview.
    Journal of nutritional science and vitaminology, 1976, Volume: 22 SUPPL

    Topics: Action Potentials; Animals; Brain Diseases; Central Nervous System; Humans; Membranes; Nervous Syste

1976
[Recent studies on thiamine, with special reference to its metabolism (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1976, Volume: 21, Issue:5

    Topics: Adenosine Triphosphate; Animals; Humans; Metabolism, Inborn Errors; Nervous System Diseases; Pyrimid

1976
Beriberi.
    Monograph series. World Health Organization, 1976, Issue:62

    Topics: Adult; Age Factors; Beriberi; Cardiovascular Diseases; Edema; Female; Food, Fortified; Humans; Hydro

1976

Trials

2 trials available for thiamine and Nervous System Disorders

ArticleYear
Alcohol, thiamin deficiency, and neuropsychological disorders.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1994, Volume: 2

    Topics: Adult; Alcohol Amnestic Disorder; Alcoholism; Brain Injuries; Cognition Disorders; Double-Blind Meth

1994
Management of acute metabolic decompensation in maple syrup urine disease: a multi-center study.
    Pediatrics international : official journal of the Japan Pediatric Society, 1999, Volume: 41, Issue:2

    Topics: Acute Disease; Adolescent; Child; Child, Preschool; Electrolytes; Female; Glucose; Health Care Surve

1999

Other Studies

42 other studies available for thiamine and Nervous System Disorders

ArticleYear
Potential thiamine deficiency and neurological symptoms in patients receiving chemotherapy for gastrointestinal cancer.
    International journal of clinical pharmacology and therapeutics, 2020, Volume: 58, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouracil; Folic Acid; G

2020
[A neurological disorder during pregnancy].
    La Revue de medecine interne, 2021, Volume: 42, Issue:8

    Topics: Female; Humans; Nervous System Diseases; Pregnancy; Thiamine; Thiamine Deficiency; Wernicke Encephal

2021
Thiamine Deficiency-Mediated Brain Mitochondrial Pathology in Alaskan Huskies with Mutation in SLC19A3.1.
    Brain pathology (Zurich, Switzerland), 2015, Volume: 25, Issue:4

    Topics: Animals; Brain; DNA, Mitochondrial; Dogs; Membrane Transport Proteins; Mitochondria; Models, Molecul

2015
Expanding the clinical and molecular spectrum of thiamine pyrophosphokinase deficiency: a treatable neurological disorder caused by TPK1 mutations.
    Molecular genetics and metabolism, 2014, Volume: 113, Issue:4

    Topics: Acidosis, Lactic; Amino Acid Sequence; Child; Child, Preschool; Female; Humans; Magnetic Resonance I

2014
Rapid reversal of severe lactic acidosis after thiamine administration in critically ill adults: a report of 3 cases.
    Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2015, Volume: 30, Issue:1

    Topics: Acidosis, Lactic; Administration, Intravenous; Adult; Aged; Critical Illness; Female; Humans; Nervou

2015
Pyruvate dehydrogenase complex deficiency: four neurological phenotypes with differing pathogenesis.
    Developmental medicine and child neurology, 2010, Volume: 52, Issue:2

    Topics: Adolescent; Brain; Female; Genetic Predisposition to Disease; Humans; Longitudinal Studies; Magnetic

2010
[Rectal aneurin in neurology].
    Gazzetta medica italiana, 1952, Aug-08, Volume: 111, Issue:8

    Topics: Humans; Nervous System Diseases; Neurology; Thiamine

1952
Nutritional deficiency and wallerian degeneration in the rat. II. Effect of thiamine deficiency on the concentration of nucleic acid and phospholipid in intact and sectioned nerves.
    The British journal of nutrition, 1954, Volume: 8, Issue:1

    Topics: Animals; Disease; Nervous System Diseases; Nucleic Acids; Phospholipids; Rats; Thiamine; Thiamine De

1954
Diabetic neuropathy: controlled therapeutic trials.
    The American journal of the medical sciences, 1954, Volume: 227, Issue:6

    Topics: Adenosine Triphosphate; Diabetes Complications; Diabetic Neuropathies; Humans; Liver Extracts; Nervo

1954
[Congestion and edema with cervicobrachial syndrome].
    Medizinische Klinik, 1956, Dec-28, Volume: 51, Issue:52

    Topics: Edema; Humans; Nervous System Diseases; Plants; Thiamine; Thoracic Outlet Syndrome

1956
[Congestion and edema with cervicobrachial syndrome].
    Medizinische Klinik, 1956, Dec-28, Volume: 51, Issue:52

    Topics: Edema; Humans; Nervous System Diseases; Plants; Thiamine; Thoracic Outlet Syndrome

1956
[Congestion and edema with cervicobrachial syndrome].
    Medizinische Klinik, 1956, Dec-28, Volume: 51, Issue:52

    Topics: Edema; Humans; Nervous System Diseases; Plants; Thiamine; Thoracic Outlet Syndrome

1956
[Congestion and edema with cervicobrachial syndrome].
    Medizinische Klinik, 1956, Dec-28, Volume: 51, Issue:52

    Topics: Edema; Humans; Nervous System Diseases; Plants; Thiamine; Thoracic Outlet Syndrome

1956
[Neurological disorder in German world war II prisoners in Egypt probably caused by a nutritional deficiency].
    Arztliche Wochenschrift, 1958, Dec-12, Volume: 13, Issue:50

    Topics: Disease; Egypt; Humans; Nervous System Diseases; Prisoners; Prisoners of War; Thiamine; Thiamine Def

1958
[Current problems in neurology].
    Semaine medicale professionelle et medico-sociale, 1958, Dec-20, Volume: 34, Issue:44

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Central Nervous System; Dermatologic Agents; Hum

1958
[The treatment of brain diseases and neurologic complications of chronic alcoholism by the combination of strychnal and massive doses of vitamin B1].
    Clinique (Paris, France), 1963, Volume: 58

    Topics: Alcoholism; Brain Diseases; Humans; Nervous System Diseases; Neurologic Manifestations; Strychnine;

1963
[On the treatment of inflammatory neurological diseases with a vitamin-enzyme combination].
    Medizinische Klinik, 1962, Sep-28, Volume: 57

    Topics: Adenine Nucleotides; Herpes Zoster; Humans; Multiple Sclerosis; Nervous System Diseases; Neuralgia;

1962
[THE CONTROL OF PAIN STATES IN NEUROLOGICAL DISEASES BY NEUROBION].
    Medizinische Klinik, 1963, Dec-13, Volume: 58

    Topics: Herpes Zoster; Humans; Nervous System Diseases; Neuralgia; Neuritis; Pain; Phantom Limb; Pyridoxine;

1963
[TRIAL OF ACTIVATED VITAMINS FOR VARIOUS NERVOUS SYSTEM DISEASES].
    Iryo, 1964, Volume: 18

    Topics: Drug Therapy; Fatty Acids; Fatty Acids, Essential; Humans; Nervous System Diseases; Niacin; Nicotini

1964
[CLINICAL APPLICATION OF A NEW VITAMIN B-12 DERIVATIVE (HYDROXOCOBALAMIN) WITH MASSIVE DOSES TO NERVOUS SYSTEM DISEASES].
    No to shinkei = Brain and nerve, 1965, Volume: 17

    Topics: Adenosine Triphosphate; Corrinoids; Hematinics; Humans; Hydroxocobalamin; Nervous System Diseases; T

1965
[CONSIDERATIONS ON ANTIALGIC EFFECTS OBTAINED IN NEUROLOGIC PATIENTS WITH THE PHARMACOLOGIC ASSOCIATION: DIISOPROPYLAMMONIUM DICHLOROETHANOATE, VITAMIN B 1, VITAMIN B 12].
    Minerva medica, 1965, Jul-07, Volume: 56

    Topics: Folic Acid; Humans; Nervous System Diseases; Pain; Quaternary Ammonium Compounds; Thiamine; Vitamin

1965
[Clinic and pathology of neurologic disorders in B1-avitaminosis].
    Deutsche Zeitschrift fur Nervenheilkunde, 1952, Volume: 167, Issue:4

    Topics: Avitaminosis; Humans; Nervous System Diseases; Thiamine; Thiamine Deficiency; Vitamin B Deficiency

1952
Prevention of nervous system damage in thiamine deficiency.
    European journal of neurology, 2006, Volume: 13, Issue:10

    Topics: Humans; Nervous System Diseases; Thiamine; Thiamine Deficiency

2006
Neurological complications of prolonged hunger strike.
    European journal of neurology, 2006, Volume: 13, Issue:10

    Topics: Adult; Confusion; Female; Humans; Hunger; Male; Nervous System Diseases; Neuropsychological Tests; P

2006
Vitamin B 1, B 2 and B 6 deficiency in neurological disorders.
    Journal of neurology, 1981, Volume: 225, Issue:2

    Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Coenzymes; Erythrocytes; Female; Glutathione R

1981
Growth hormone deficiency and empty sella in DIDMOAD syndrome: an endocrine study.
    Archives of disease in childhood, 1995, Volume: 73, Issue:3

    Topics: Anemia, Sideroblastic; C-Peptide; Empty Sella Syndrome; Female; Growth Hormone; Humans; Infant; Nerv

1995
[Nervous syndrome in sheep on the Ivory Coast. II. Economic impact, trials and cost-benefit analysis of preventive plans].
    Revue d'elevage et de medecine veterinaire des pays tropicaux, 1993, Volume: 46, Issue:3

    Topics: Animals; Cost-Benefit Analysis; Cote d'Ivoire; Nervous System Diseases; Sheep; Sheep Diseases; Thiam

1993
Subclinical beriberi polyneuropathy in the low income group: an investigation with special tools on possible patients with suspected complaints.
    European journal of clinical nutrition, 1996, Volume: 50, Issue:8

    Topics: Adolescent; Adult; Beriberi; Cohort Studies; Diet Surveys; Energy Intake; Family; Female; Humans; In

1996
Nutritional disorders in a concentration camp.
    Journal of the American College of Nutrition, 1997, Volume: 16, Issue:4

    Topics: Adult; Body Water; Cardiovascular Diseases; China; Concentration Camps; Exercise; Fever; Gastrointes

1997
The value of thiamine replacement in chronic alcoholism: a reminder.
    The British journal of addiction to alcohol and other drugs, 1979, Volume: 74, Issue:2

    Topics: Alcoholism; Humans; Nervous System Diseases; Thiamine; Thiamine Deficiency

1979
Is calcium deficiency related to thiamine-dependent neuropathy in pigeon?
    Brain research, 1975, Sep-05, Volume: 94, Issue:3

    Topics: Animals; Calcium; Calcium, Dietary; Columbidae; Magnesium; Nervous System Diseases; Seizures; Telenc

1975
A thiamine responsive nervous disease in saltwater crocodiles (Crocodylus porosus).
    The Veterinary record, 1992, Oct-10, Volume: 131, Issue:15

    Topics: Alligators and Crocodiles; Animal Feed; Animals; Injections, Intramuscular; Meat; Nervous System Dis

1992
Physiopathologic changes in lambs fed with Astragalus lusitanicus Lam.
    Veterinary and human toxicology, 1987, Volume: 29, Issue:5

    Topics: Animals; Fabaceae; Nervous System Diseases; Plants, Medicinal; Sheep; Sheep Diseases; Thiamine

1987
Neurotoxicity of metronidazole.
    Annals of internal medicine, 1985, Volume: 103, Issue:1

    Topics: Antimetabolites; Humans; Metronidazole; Nervous System Diseases; Thiamine

1985
Effect of thiamin status on the metabolism of linamarin in rats.
    Annals of nutrition & metabolism, 1985, Volume: 29, Issue:5

    Topics: Animals; Cyanides; Manihot; Nervous System Diseases; Nitriles; Rats; Rats, Inbred Strains; Thiamine;

1985
[Vitamins in neurology].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Avitaminosis; Folic Acid; Humans; Nervous System; Nervous System Diseases; Niacinamide; Nicotinic Ac

1969
Uremic neuropathy. Monitoring of transketolase activity inhibition in a child.
    American journal of diseases of children (1960), 1973, Volume: 125, Issue:2

    Topics: Brain; Child; Electromyography; Female; Humans; Kidney Failure, Chronic; Leg; Nervous System Disease

1973
[Study of the therapeutic action of a combination of vitamins B1, B6 and hydroxocobalamin in large doses].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1968, Jan-20, Volume: 44, Issue:4

    Topics: Adult; Aged; Anemia; Brain Diseases; Epilepsy; Facial Paralysis; Fatty Liver; Female; Hemiplegia; He

1968
Mechanisms of neuropathy.
    The New England journal of medicine, 1971, 11-11, Volume: 285, Issue:20

    Topics: Erythrocytes; Glycerophosphates; Heptoses; Humans; Nervous System Diseases; Peripheral Nerves; Perip

1971
Deficiency diseases of the nervous system secondary to alcoholism.
    Postgraduate medicine, 1971, Volume: 50, Issue:3

    Topics: Alcohol Amnestic Disorder; Alcoholism; Amblyopia; Beriberi; Cerebellar Diseases; Deficiency Diseases

1971
[Use of vitamins B-1 and B-12 combined with UTP in the treatment of various diseases of the nervous and muscular systems].
    La Clinica terapeutica, 1969, Jan-15, Volume: 48, Issue:1

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Muscular Diseases; Nervous System Diseases; Thiamine

1969
Effects of pyrithiamin injection into the brain of rats.
    The Journal of nutrition, 1970, Volume: 100, Issue:4

    Topics: Administration, Oral; Animals; Antimetabolites; Brain; Female; Fluorescence; Injections; Methods; Ne

1970
[Causal therapy of pain states in neurologic diseases].
    Zeitschrift fur Allgemeinmedizin, 1970, Apr-10, Volume: 46, Issue:10

    Topics: Analgesics; Antipyrine; Humans; Methylamines; Nervous System Diseases; Pain; Pyridoxine; Sulfonic Ac

1970
[Supplementary findings on vitamin B1 in pediatrics. 3. Autonomic dysfunction and vitamin B1].
    Nihon Shonika Gakkai zasshi. Acta paediatrica Japonica, 1967, Aug-01, Volume: 71, Issue:8

    Topics: Adolescent; Autonomic Nervous System; Child; Female; Humans; Male; Nervous System Diseases; Thiamine

1967
Vitamins of the B complex.
    British medical journal, 1968, Dec-14, Volume: 4, Issue:5632

    Topics: Aged; Alcoholism; Anemia, Hypochromic; Avitaminosis; Beriberi; Heart Failure; Humans; Isoniazid; Ner

1968