thiamine has been researched along with Nerve Degeneration in 15 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Chronic alcoholism is usually associated with thiamine deficiency (TD) which is known to induce selective neurodegeneration in the brain." | 7.75 | Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase. ( Fan, Z; Ke, ZJ; Luo, J; Wang, X, 2009) |
| "Wernicke's encephalopathy (WE) is characterized by lesions in thalamus, hypothalamus (including mammillary nuclei), and inferior colliculi, results in serious disabilities, has an etiology of thiamine deficiency, is treatable with thiamine, and occurs most commonly with alcoholism." | 7.74 | Development and resolution of brain lesions caused by pyrithiamine- and dietary-induced thiamine deficiency and alcohol exposure in the alcohol-preferring rat: a longitudinal magnetic resonance imaging and spectroscopy study. ( Adalsteinsson, E; Bell, RL; Pfefferbaum, A; Sullivan, EV, 2007) |
| " Thiamine deficiency (TD) in rats is a model for the study of cellular and molecular mechanisms that lead to selective neuronal loss caused by chronic oxidative deficits." | 3.76 | Neurodegeneration in thiamine deficient rats-A longitudinal MRI study. ( Assaf, Y; Biton, IE; Dror, V; Eliash, S; Fattal-Valevski, A; Rehavi, M, 2010) |
| " Chronic alcoholism is usually associated with thiamine deficiency (TD) which is known to induce selective neurodegeneration in the brain." | 3.75 | Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase. ( Fan, Z; Ke, ZJ; Luo, J; Wang, X, 2009) |
| "Wernicke's encephalopathy (WE) is characterized by lesions in thalamus, hypothalamus (including mammillary nuclei), and inferior colliculi, results in serious disabilities, has an etiology of thiamine deficiency, is treatable with thiamine, and occurs most commonly with alcoholism." | 3.74 | Development and resolution of brain lesions caused by pyrithiamine- and dietary-induced thiamine deficiency and alcohol exposure in the alcohol-preferring rat: a longitudinal magnetic resonance imaging and spectroscopy study. ( Adalsteinsson, E; Bell, RL; Pfefferbaum, A; Sullivan, EV, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mouton-Liger, F | 1 |
| Rebillat, AS | 1 |
| Gourmaud, S | 1 |
| Paquet, C | 1 |
| Leguen, A | 1 |
| Dumurgier, J | 1 |
| Bernadelli, P | 1 |
| Taupin, V | 1 |
| Pradier, L | 1 |
| Rooney, T | 1 |
| Hugon, J | 1 |
| Bâ, A | 1 |
| Ke, ZJ | 1 |
| Wang, X | 1 |
| Fan, Z | 1 |
| Luo, J | 1 |
| Dror, V | 1 |
| Eliash, S | 1 |
| Rehavi, M | 1 |
| Assaf, Y | 1 |
| Biton, IE | 1 |
| Fattal-Valevski, A | 1 |
| UMRATH, K | 1 |
| Pfefferbaum, A | 1 |
| Adalsteinsson, E | 1 |
| Bell, RL | 1 |
| Sullivan, EV | 1 |
| Oliveira, FA | 1 |
| Galan, DT | 1 |
| Ribeiro, AM | 1 |
| Santos Cruz, J | 1 |
| Carlton, WW | 1 |
| Bettendorff, L | 1 |
| Mastrogiacomo, F | 1 |
| Wins, P | 1 |
| Kish, SJ | 1 |
| Grisar, T | 1 |
| Ball, MJ | 1 |
| Gibson, GE | 1 |
| Zhang, H | 1 |
| Hayashi, T | 1 |
| Tanohata, K | 1 |
| Kunimoto, M | 1 |
| Inoue, K | 1 |
| Becker, KW | 1 |
| Kienecker, EW | 1 |
| Dick, P | 1 |
| Ramos Seisdedos, G | 1 |
| Casas, P | 1 |
| Beltrán de Heredia, J | 1 |
| Morgan, KT | 1 |
| Yonezawa, T | 1 |
| Iwanami, H | 1 |
2 reviews available for thiamine and Nerve Degeneration
| Article | Year |
|---|---|
Metabolic and structural role of thiamine in nervous tissues.
Topics: Animals; Apoptosis; Brain; Cell Membrane; Hippocampus; Humans; Nerve Degeneration; Neurogenesis; Neu | 2008 |
Interactions of oxidative stress with thiamine homeostasis promote neurodegeneration.
Topics: Animals; Brain Chemistry; Homeostasis; Humans; Nerve Degeneration; Oxidative Stress; Phosphates; Thi | 2002 |
13 other studies available for thiamine and Nerve Degeneration
| Article | Year |
|---|---|
PKR downregulation prevents neurodegeneration and β-amyloid production in a thiamine-deficient model.
Topics: Amyloid; Amyloid beta-Peptides; Animals; Brain; Caspase 3; Disease Models, Animal; Down-Regulation; | 2015 |
Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase.
Topics: Alcoholism; Amprolium; Animals; Cell Death; Cells, Cultured; Central Nervous System Depressants; Coc | 2009 |
Neurodegeneration in thiamine deficient rats-A longitudinal MRI study.
Topics: Analysis of Variance; Animals; Anisotropy; Brain Mapping; Diffusion Tensor Imaging; Disease Progress | 2010 |
[Aneurin and acetylcholine in nerve degeneration].
Topics: Acetylcholine; Nerve Degeneration; Peripheral Nerves; Thiamine | 1951 |
Development and resolution of brain lesions caused by pyrithiamine- and dietary-induced thiamine deficiency and alcohol exposure in the alcohol-preferring rat: a longitudinal magnetic resonance imaging and spectroscopy study.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Antimetabolites; Biomarkers; Brain; | 2007 |
Thiamine deficiency during pregnancy leads to cerebellar neuronal death in rat offspring: role of voltage-dependent K+ channels.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebellum; Female; Fetal Nutrition Disorders; Membrane Pot | 2007 |
Studies on the induction of hydrocephalus and spongy degeneration by cuprizone feeding and attempts to antidote the toxicity.
Topics: Animals; Chelating Agents; Chlorothiazide; Copper; Folic Acid; Hydrocephalus; Male; Mice; Nerve Dege | 1967 |
Low thiamine diphosphate levels in brains of patients with frontal lobe degeneration of the non-Alzheimer's type.
Topics: Adult; Age of Onset; Aged; Analysis of Variance; Autopsy; Cerebral Cortex; Citrate (si)-Synthase; Fe | 1997 |
Marchiafava-Bignami disease with resolving symmetrical putaminal lesion.
Topics: Aged; Alcohol-Induced Disorders, Nervous System; Apraxias; Atrophy; Chronic Disease; Corpus Callosum | 2002 |
A contribution to the scientific assessment of degenerative and regenerative processes of peripheral nerve fibers following axonotmesis under the systemic administration of vitamins B1, B6 and B12--light and electron microscopy findings of the saphenous n
Topics: Animals; Axons; Dose-Response Relationship, Drug; Hindlimb; Microscopy, Electron; Nerve Degeneration | 1990 |
[Peripheral nerve injury and its muscular repercussions. Experimental study of various therapeutic methods].
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Muscles; Nerve Degeneration; Nerve Regen | 1970 |
An ultrastructural study of ovine polio-encephalomalacia.
Topics: Animals; Blood Proteins; Cerebral Cortex; Cytoplasmic Granules; Edema; Encephalomalacia; Endothelium | 1973 |
An experimental study of thiamine deficiency in nervous tissue, using tissue culture technics.
Topics: Animals; Antimetabolites; Cerebellum; Ganglia, Spinal; In Vitro Techniques; Mice; Myelin Sheath; Ner | 1966 |