Page last updated: 2024-10-20

thiamine and Marchiafava-Bignami Disease

thiamine has been researched along with Marchiafava-Bignami Disease in 13 studies

thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.

Marchiafava-Bignami Disease: A neurodegenerative condition that is characterized by demyelination or necrosis of the CORPUS CALLOSUM. Symptoms include DEPRESSION; PARANOIA; DEMENTIA; SEIZURES; and ATAXIA which can progress to COMA and death in a few months. Marchiafava-Bignami syndrome is seen often in alcoholics but has been found in non-alcoholics as well.

Research Excerpts

ExcerptRelevanceReference
" Chronic use of ethanol often leads to the development of neurodegenerative syndromes, which cause morphological and functional impairments such as foetal alcohol syndrome in newborns exposed to ethanol during pregnancy, Wernicke-Korsakoff Syndrome and, more rarely, Marchiafava-Bignami disease (MBD)."6.55Thiamine deficiency, oxidative metabolic pathways and ethanol-induced neurotoxicity: how poor nutrition contributes to the alcoholic syndrome, as Marchiafava-Bignami disease. ( Bezerra, FR; de Oliveira, FR; Fernandes, LMP; Fontes-Júnior, EA; Lima, RR; Maia, CSF; Monteiro, MC; Silva, ML, 2017)
"As thiamine deficiency is frequently associated with alcoholism, malnutrition and prolonged vomiting; we recommend prompt treatment of MBD with parenteral thiamine in such subjects."4.90Diagnosis and management of Marchiafava-Bignami disease: a review of CT/MRI confirmed cases. ( Fujioka, S; Hillbom, M; Juvela, S; Leone, MA; Saloheimo, P; Wszolek, ZK, 2014)
" Chronic use of ethanol often leads to the development of neurodegenerative syndromes, which cause morphological and functional impairments such as foetal alcohol syndrome in newborns exposed to ethanol during pregnancy, Wernicke-Korsakoff Syndrome and, more rarely, Marchiafava-Bignami disease (MBD)."2.55Thiamine deficiency, oxidative metabolic pathways and ethanol-induced neurotoxicity: how poor nutrition contributes to the alcoholic syndrome, as Marchiafava-Bignami disease. ( Bezerra, FR; de Oliveira, FR; Fernandes, LMP; Fontes-Júnior, EA; Lima, RR; Maia, CSF; Monteiro, MC; Silva, ML, 2017)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's9 (69.23)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Shao, J1
Bai, R1
Duan, G1
Guan, Y1
Cui, L1
Deng, H1
Kinsley, S1
Giovane, RA1
Daly, S1
Shulman, D1
Tsai, CY1
Huang, PK1
Huang, P1
Hillbom, M1
Saloheimo, P1
Fujioka, S1
Wszolek, ZK1
Juvela, S1
Leone, MA1
Duray, MC1
De Maeseneire, C1
Rutgers, MP1
Gille, M1
Kakkar, C1
Prakashini, K1
Polnaya, A1
Pinter, G1
Borbely, K1
Peter, L1
Mehrzad, R1
Ho, MG1
Fernandes, LMP1
Bezerra, FR1
Monteiro, MC1
Silva, ML1
de Oliveira, FR1
Lima, RR1
Fontes-Júnior, EA1
Maia, CSF1
Raina, S1
Mahesh, DM1
Mahajan, J1
Kaushal, SS1
Gupta, D1
Dhiman, DS1
Aggarwal, A1
Khandelwal, A1
Jiloha, RC1
SUKHORUKOVA, LI1
Aggunlu, L1
Oner, Y1
Kocer, B1
Akpek, S1

Reviews

2 reviews available for thiamine and Marchiafava-Bignami Disease

ArticleYear
Diagnosis and management of Marchiafava-Bignami disease: a review of CT/MRI confirmed cases.
    Journal of neurology, neurosurgery, and psychiatry, 2014, Volume: 85, Issue:2

    Topics: Alcoholism; Corpus Callosum; Diagnosis, Differential; Humans; Magnetic Resonance Imaging; Marchiafav

2014
Thiamine deficiency, oxidative metabolic pathways and ethanol-induced neurotoxicity: how poor nutrition contributes to the alcoholic syndrome, as Marchiafava-Bignami disease.
    European journal of clinical nutrition, 2017, Volume: 71, Issue:5

    Topics: Alcohol Drinking; Alcoholism; Ethanol; Marchiafava-Bignami Disease; Neurotoxicity Syndromes; Oxidati

2017

Other Studies

11 other studies available for thiamine and Marchiafava-Bignami Disease

ArticleYear
Intermittent alien hand syndrome caused by Marchiafava-Bignami disease: A case report.
    Medicine, 2019, Volume: 98, Issue:34

    Topics: Alcoholism; Alien Limb Phenomenon; Corpus Callosum; Humans; Magnetic Resonance Imaging; Male; Marchi

2019
Rare case of Marchiafava-Bignami disease due to thiamine deficiency and malnutrition.
    BMJ case reports, 2020, Dec-10, Volume: 13, Issue:12

    Topics: Aged; Alcoholism; Corpus Callosum; Diagnosis, Differential; Female; Humans; Magnetic Resonance Imagi

2020
Simultaneous acute Marchiafava-Bignami disease and central pontine myelinolysis: A case report of a challenging diagnosis.
    Medicine, 2018, Volume: 97, Issue:8

    Topics: Adult; Alcoholism; Humans; Magnetic Resonance Imaging; Male; Marchiafava-Bignami Disease; Myelinolys

2018
Acute reversible Marchiafava-Bignami disease with hypernatremia: a "callosal myelinolysis"?
    Revue neurologique, 2014, Volume: 170, Issue:3

    Topics: Acute Disease; Alcoholism; Combined Modality Therapy; Corpus Callosum; Emergencies; Female; Fluid Th

2014
Acute Marchiafava-Bignami disease: clinical and serial MRI correlation.
    BMJ case reports, 2014, May-21, Volume: 2014

    Topics: Diffusion Magnetic Resonance Imaging; Humans; Male; Marchiafava-Bignami Disease; Middle Aged; Thiami

2014
[Marchiafava-Bignami disease (Case-report)].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2016, Volume: 18, Issue:2

    Topics: Alcoholism; Corpus Callosum; Humans; Magnetic Resonance Imaging; Marchiafava-Bignami Disease; Thiami

2016
Mutism Caused by Severe Demyelination in a Patient With Marchiafava-Bignami Disease.
    The Journal of emergency medicine, 2016, Volume: 51, Issue:6

    Topics: Alcoholism; Female; Gastric Bypass; Glucose; Humans; Magnetic Resonance Imaging; Marchiafava-Bignami

2016
Marchiafava-Bignami disease.
    The Journal of the Association of Physicians of India, 2008, Volume: 56

    Topics: Adult; Aged; Alcoholism; Corpus Callosum; Humans; Magnetic Resonance Imaging; Male; Marchiafava-Bign

2008
A case of marchiafava bignami disease: complete recovery with thiamine.
    The Journal of neuropsychiatry and clinical neurosciences, 2011,Spring, Volume: 23, Issue:2

    Topics: Brain; Humans; Marchiafava-Bignami Disease; Middle Aged; Thiamine; Treatment Outcome

2011
[MARCHIAFAVA-BIGNAMI SYNDROME IN EXPERIMENTAL CHRONIC ALCOHOLISM].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1964, Volume: 64

    Topics: Alcoholic Intoxication; Alcoholism; Brain Diseases; Corpus Callosum; Dogs; Marchiafava-Bignami Disea

1964
The value of diffusion-weighted imaging in the diagnosis of Marchiafava-Bignami disease: apropos of a case.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2008, Volume: 18, Issue:2

    Topics: Adult; Diffusion Magnetic Resonance Imaging; Humans; Male; Marchiafava-Bignami Disease; Pyridoxine;

2008