Page last updated: 2024-10-20

thiamine and Malaria

thiamine has been researched along with Malaria in 7 studies

thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
"The effect of a combined supplement of iron, thiamine, riboflavin and vitamin C on malarial incidence in 5 to 14-year-old children was tested in a malnourished rural community in a region of The Gambia noted for high prevalence of malaria during the rainy season."5.06Effect of supplementary vitamins and iron on malaria indices in rural Gambian children. ( Bates, CJ; Gelman, W; Lamb, WH; Powers, HJ; Webb, E, 1987)
" Primate malaria parasites can synthesize vitamin B1 (thiamine) de novo but rodent malaria and other genome-sequenced apicomplexans cannot, as the three essential genes responsible for this pathway are absent in their genomes."3.88De novo synthesis of thiamine (vitamin B1) is the ancestral state in Plasmodium parasites - evidence from avian haemosporidians. ( Bensch, S; Hellgren, O; Videvall, E, 2018)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mosnier, E1
Niemetzky, F1
Stroot, J1
Pommier de Santi, V1
Brousse, P1
Guarmit, B1
Blanchet, D1
Ville, M1
Abboud, P1
Djossou, F1
Nacher, M1
Hellgren, O1
Bensch, S1
Videvall, E1
Abdel-Haleem, AM1
Hefzi, H1
Mineta, K1
Gao, X1
Gojobori, T1
Palsson, BO1
Lewis, NE1
Jamshidi, N1
Kronenberger, T1
Schettert, I1
Wrenger, C1
SINGER, I1
Bates, CJ1
Powers, HJ1
Lamb, WH1
Gelman, W1
Webb, E1
Somogyi, JC1

Reviews

1 review available for thiamine and Malaria

ArticleYear
Targeting the vitamin biosynthesis pathways for the treatment of malaria.
    Future medicinal chemistry, 2013, Volume: 5, Issue:7

    Topics: Antimalarials; Enzyme Inhibitors; Humans; Malaria; Plasmodium; Protozoan Proteins; Thiamine; Vitamin

2013

Trials

1 trial available for thiamine and Malaria

ArticleYear
Effect of supplementary vitamins and iron on malaria indices in rural Gambian children.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987, Volume: 81, Issue:2

    Topics: Adolescent; Ascorbic Acid; Child; Child, Preschool; Erythrocyte Indices; Female; Ferrous Compounds;

1987

Other Studies

5 other studies available for thiamine and Malaria

ArticleYear
A Large Outbreak of Thiamine Deficiency Among Illegal Gold Miners in French Guiana.
    The American journal of tropical medicine and hygiene, 2017, Volume: 96, Issue:5

    Topics: Adult; Aged; Beriberi; Criminal Behavior; Disease Outbreaks; Female; French Guiana; Gold; Humans; Ma

2017
De novo synthesis of thiamine (vitamin B1) is the ancestral state in Plasmodium parasites - evidence from avian haemosporidians.
    Parasitology, 2018, Volume: 145, Issue:8

    Topics: Animals; Biosynthetic Pathways; Birds; Genome, Protozoan; Haemosporida; Malaria; Malaria, Avian; Phy

2018
Functional interrogation of Plasmodium genus metabolism identifies species- and stage-specific differences in nutrient essentiality and drug targeting.
    PLoS computational biology, 2018, Volume: 14, Issue:1

    Topics: Animals; Choline; Culicidae; Disease Models, Animal; Food; Gene Deletion; Gene Expression Regulation

2018
Tissue thiamine changes in rats with experimental trypanosomiasis or malaria.
    Experimental parasitology, 1961, Volume: 11

    Topics: Animals; Malaria; Rats; Thiamine; Trypanosomiasis

1961
[Definition and significance of the antivitamins].
    Bibliotheca nutritio et dieta, 1966, Volume: 8

    Topics: Antimetabolites; Coccidiosis; Folic Acid Antagonists; Leukemia; Malaria; Thiamine; Vitamins

1966