thiamine has been researched along with MELAS Syndrome in 3 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanaka, J | 1 |
| Nagai, T | 1 |
| Arai, H | 1 |
| Inui, K | 1 |
| Yamanouchi, H | 1 |
| Goto, Y | 1 |
| Nonaka, I | 1 |
| Okada, S | 1 |
| Kuroda, Y | 1 |
| Ito, M | 1 |
| Naito, E | 1 |
| Yokota, I | 1 |
| Matsuda, J | 1 |
| Saijo, T | 1 |
| Kondo, S | 1 |
| Yoneda, Y | 1 |
| Miyazaki, M | 1 |
| Mori, K | 1 |
| Iwamoto, H | 1 |
| Yoneda, M | 1 |
1 review available for thiamine and MELAS Syndrome
| Article | Year |
|---|---|
[Mitochondrial dysfunction in migraine].
Topics: Coenzymes; Diagnosis, Differential; DNA, Mitochondrial; Humans; MELAS Syndrome; Migraine Disorders; | 2002 |
1 trial available for thiamine and MELAS Syndrome
| Article | Year |
|---|---|
Treatment of mitochondrial encephalomyopathy with a combination of cytochrome C and vitamins B1 and B2.
Topics: Adolescent; Adult; Cerebrospinal Fluid Proteins; Child; Child, Preschool; Cytochrome c Group; Cytoch | 1997 |
1 other study available for thiamine and MELAS Syndrome
| Article | Year |
|---|---|
Concomitant administration of sodium dichloroacetate and vitamin B1 for lactic acidemia in children with MELAS syndrome.
Topics: Acidosis, Lactic; Administration, Oral; Child; Dichloroacetic Acid; Drug Monitoring; Drug Therapy, C | 1997 |