thiamine has been researched along with Lassitude in 27 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We found no beneficial effect on fatigue from thiamine taken in doses of 300 mg per day for 12 weeks following high-dose treatment." | 9.51 | Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study. ( Bager, P; Dahlerup, JF; Hvas, CL; Rud, CL, 2022) |
| "Our study was designed to evaluate the short-term effects of sulbutiamine on fatigue in patients with MS." | 7.85 | Sulbutiamine shows promising results in reducing fatigue in patients with multiple sclerosis. ( Kaleağası, H; Sevim, S; Taşdelen, B, 2017) |
| "A previous study on fatigue and related disorders in inflammatory bowel disease, patients improved after therapy with high-dose thiamine." | 7.80 | High-dose thiamine improves fatigue after stroke: a report of three cases. ( Careddu, P; Catalano, ML; Costantini, A; Notarangelo, C; Pala, MI, 2014) |
| "To demonstrate that fatigue and other disorders related to ulcerative colitis and Crohn's disease are the manifestation of an intracellular mild thiamine deficiency and not due to malabsorbtion, augmented requirements, or nutritional factors, and that this dysfunction is curable with high doses of thiamine administered orally or parenterally." | 7.79 | Thiamine and fatigue in inflammatory bowel diseases: an open-label pilot study. ( Costantini, A; Pala, MI, 2013) |
| "The anti-fatigue effect of dicethiamine hydrochloride (DCET) was assessed and compared to that of thiamine hydrochloride (VB(1)HCl) in rats." | 7.76 | Anti-fatigue effect of dicethiamine hydrochloride is likely associated with excellent absorbability and high transformability in tissues as a Vitamin B(1). ( Hoshino, H; Nishi, S; Nozaki, S; Shimizu, T; Watanabe, Y, 2010) |
| "We found no beneficial effect on fatigue from thiamine taken in doses of 300 mg per day for 12 weeks following high-dose treatment." | 5.51 | Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study. ( Bager, P; Dahlerup, JF; Hvas, CL; Rud, CL, 2022) |
| "Our study was designed to evaluate the short-term effects of sulbutiamine on fatigue in patients with MS." | 3.85 | Sulbutiamine shows promising results in reducing fatigue in patients with multiple sclerosis. ( Kaleağası, H; Sevim, S; Taşdelen, B, 2017) |
| "In a previous study on fatigue and related disorders in inflammatory bowel disease (IBD), we observed that IBD patients improved after treatment with high-dose thiamine." | 3.80 | Thiamine and Hashimoto's thyroiditis: a report of three cases. ( Costantini, A; Pala, MI, 2014) |
| "A previous study on fatigue and related disorders in inflammatory bowel disease, patients improved after therapy with high-dose thiamine." | 3.80 | High-dose thiamine improves fatigue after stroke: a report of three cases. ( Careddu, P; Catalano, ML; Costantini, A; Notarangelo, C; Pala, MI, 2014) |
| "To demonstrate that fatigue and other disorders related to ulcerative colitis and Crohn's disease are the manifestation of an intracellular mild thiamine deficiency and not due to malabsorbtion, augmented requirements, or nutritional factors, and that this dysfunction is curable with high doses of thiamine administered orally or parenterally." | 3.79 | Thiamine and fatigue in inflammatory bowel diseases: an open-label pilot study. ( Costantini, A; Pala, MI, 2013) |
| "The anti-fatigue effect of dicethiamine hydrochloride (DCET) was assessed and compared to that of thiamine hydrochloride (VB(1)HCl) in rats." | 3.76 | Anti-fatigue effect of dicethiamine hydrochloride is likely associated with excellent absorbability and high transformability in tissues as a Vitamin B(1). ( Hoshino, H; Nishi, S; Nozaki, S; Shimizu, T; Watanabe, Y, 2010) |
| " The adverse event frequency in the therapy groups was similar to that in the placebo group." | 2.82 | Efficacy and Safety of "URSA Complex" in Subjects with Physical Fatigue: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial. ( Cho, DY; Kim, KM; Kim, KS; Kim, MJ; Kim, YS; Park, KC; Song, SW; Yang, SW, 2016) |
| "Spinocerebellar ataxia type 2 is a genetic disorder characterised by the degeneration of the cerebellum, its connections and degeneration in brainstem areas." | 1.39 | Thiamine and spinocerebellar ataxia type 2. ( Colangeli, M; Costantini, A; Pala, MI; Savelli, S, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (44.44) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 10 (37.04) | 24.3611 |
| 2020's | 3 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Bager, P | 2 |
| Hvas, CL | 2 |
| Rud, CL | 2 |
| Dahlerup, JF | 2 |
| LeBlanc, JF | 1 |
| Hart, AL | 1 |
| Sevim, S | 1 |
| Kaleağası, H | 1 |
| Taşdelen, B | 1 |
| Costantini, A | 6 |
| Pala, MI | 6 |
| Tundo, S | 1 |
| Matteucci, P | 1 |
| Nappo, A | 1 |
| Zappone, A | 1 |
| Catalano, ML | 1 |
| Notarangelo, C | 1 |
| Careddu, P | 1 |
| Kim, KM | 1 |
| Kim, MJ | 1 |
| Song, SW | 1 |
| Cho, DY | 1 |
| Park, KC | 1 |
| Yang, SW | 1 |
| Kim, YS | 1 |
| Kim, KS | 1 |
| Nozaki, S | 2 |
| Mizuma, H | 1 |
| Tanaka, M | 1 |
| Jin, G | 1 |
| Tahara, T | 1 |
| Mizuno, K | 1 |
| Yamato, M | 1 |
| Okuyama, K | 1 |
| Eguchi, A | 1 |
| Akimoto, K | 1 |
| Kitayoshi, T | 1 |
| Mochizuki-Oda, N | 1 |
| Kataoka, Y | 1 |
| Watanabe, Y | 2 |
| Shimizu, T | 1 |
| Hoshino, H | 1 |
| Nishi, S | 1 |
| Ikarashi, N | 1 |
| Fukazawa, Y | 1 |
| Toda, T | 1 |
| Ishii, M | 1 |
| Ochiai, W | 1 |
| Usukura, M | 1 |
| Sugiyama, K | 1 |
| Colangeli, M | 1 |
| Savelli, S | 1 |
| MATRACIA, S | 1 |
| BARRRSI, M | 1 |
| PASQUALINO, A | 1 |
| KARPUKHINA, IuL | 1 |
| VENTURA, U | 1 |
| SUGIURA, Y | 1 |
| KAWAKITA, Y | 1 |
| IGAWA, G | 1 |
| NAGAHAMA, S | 1 |
| HAMANAKA, T | 1 |
| TSURUMARU, Y | 1 |
| KURAUCHI, K | 1 |
| MORI, H | 1 |
| KUWABARA, Y | 1 |
| MIYASHITA, T | 1 |
| WADA, M | 1 |
| MORITA, S | 1 |
| TAKAHASHI, S | 1 |
| FUKUHARA, A | 1 |
| ITACHI, K | 1 |
| OHOBA, K | 1 |
| Kodama, S | 1 |
| Yagi, R | 1 |
| Ninomiya, M | 1 |
| Goji, K | 1 |
| Takahashi, T | 1 |
| Morishita, Y | 1 |
| Matsuo, T | 1 |
| Tiev, KP | 1 |
| Cabane, J | 1 |
| Imbert, JC | 1 |
| Early, RG | 1 |
| Carlson, BR | 1 |
| Sovena, E | 1 |
| Nose, T | 1 |
| Yasuda, K | 1 |
| Nakama, M | 1 |
| Adachi, S | 1 |
| Kowa, Y | 1 |
| Yamada, S | 1 |
| Ishikawa, S | 1 |
| Chibata, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Thiamin Against Robust IBD Fatigue[NCT03634735] | Phase 4 | 40 participants (Actual) | Interventional | 2018-11-27 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for thiamine and Lassitude
| Article | Year |
|---|---|
Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
Topics: Chronic Disease; Colitis; Fatigue; Humans; Inflammatory Bowel Diseases; Thiamine | 2022 |
Efficacy and Safety of "URSA Complex" in Subjects with Physical Fatigue: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial.
Topics: Adult; Double-Blind Method; Fatigue; Humans; Inositol; Middle Aged; Panax; Plant Extracts; Taurine; | 2016 |
[Treatment of chronic postinfectious fatigue: randomized double-blind study of two doses of sulbutiamine (400-600 mg/day) versus placebo].
Topics: Adult; Antidepressive Agents; Bacterial Infections; Chronic Disease; Dose-Response Relationship, Dru | 1999 |
Water-soluble vitamin therapy in the delay of fatigue from physical activity in hot climatic conditions.
Topics: Acclimatization; Acetates; Adolescent; Adult; Analysis of Variance; Citric Acid Cycle; Clinical Tria | 1969 |
23 other studies available for thiamine and Lassitude
| Article | Year |
|---|---|
Editorial: a pipe dream fulfilled? A therapeutic option for fatigue in IBD. Authors' reply.
Topics: Colitis; Fatigue; Fatigue Syndrome, Chronic; Humans; Inflammatory Bowel Diseases; Thiamine | 2021 |
Editorial: a pipe dream fulfilled? A therapeutic option for fatigue in IBD.
Topics: Colitis; Fatigue; Fatigue Syndrome, Chronic; Humans; Inflammatory Bowel Diseases; Thiamine | 2021 |
Sulbutiamine shows promising results in reducing fatigue in patients with multiple sclerosis.
Topics: Adolescent; Adult; Central Nervous System Agents; Disability Evaluation; Fatigue; Female; Humans; Im | 2017 |
High-dose thiamine improves the symptoms of fibromyalgia.
Topics: Adult; Fatigue; Female; Fibromyalgia; Humans; Middle Aged; Pain Measurement; Thiamine; Treatment Out | 2013 |
High dose thiamine improves fatigue in multiple sclerosis.
Topics: Adult; Aged; Drug Administration Schedule; Fatigue; Female; Humans; Male; Middle Aged; Multiple Scle | 2013 |
Thiamine and Hashimoto's thyroiditis: a report of three cases.
Topics: Adult; Fatigue; Female; Hashimoto Disease; Hormone Replacement Therapy; Humans; Middle Aged; Thiamin | 2014 |
High-dose thiamine improves fatigue after stroke: a report of three cases.
Topics: Aged; Aged, 80 and over; Brain Ischemia; Fatigue; Female; Humans; Male; Stroke; Thiamine; Thiamine D | 2014 |
Thiamine tetrahydrofurfuryl disulfide improves energy metabolism and physical performance during physical-fatigue loading in rats.
Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Fatigue; Fursultiamin; Male; Muscle, Skeletal; O | 2009 |
Anti-fatigue effect of dicethiamine hydrochloride is likely associated with excellent absorbability and high transformability in tissues as a Vitamin B(1).
Topics: Absorption; Administration, Oral; Animals; Fatigue; Male; Pyrimidines; Rats; Rats, Sprague-Dawley; T | 2010 |
Effect of Conclevan on endurance capacity in mice.
Topics: Ammonia; Animals; Blood Glucose; Corticosterone; Fatigue; Glutamine; Lactic Acid; Liver; Male; Mice; | 2012 |
Thiamine and spinocerebellar ataxia type 2.
Topics: Fatigue; Humans; Male; Middle Aged; Spinocerebellar Ataxias; Thiamine; Vitamin B Complex | 2013 |
Thiamine and fatigue in inflammatory bowel diseases: an open-label pilot study.
Topics: Adult; Fatigue; Female; Humans; Inflammatory Bowel Diseases; Male; Middle Aged; Pilot Projects; Thia | 2013 |
[Action of cocarboxylase and vitamin B1 on carbohydrates in experimental fatigue].
Topics: Blood Glucose; Fatigue; Glycogen; Glycogenolysis; Liver; Muscles; Thiamine; Thiamine Pyrophosphate | 1953 |
[Restoration processes following muscular work following intake of food with various contents of vitamin B1].
Topics: Exercise; Fatigue; Food; Humans; Muscles; Thiamine | 1955 |
[Effect of fatigue on the thiamine (free and phosphorated) content of rat tissues].
Topics: Animals; Biochemical Phenomena; Fatigue; Rats; Thiamine | 1959 |
[EFFECT OF THIAMINE TETRAHYDROFURFURYL DISULFIDE (TTFD) IN ATHLETES].
Topics: Athletes; Fatigue; Fursultiamin; Humans; Physical Education and Training; Sports Medicine; Thiamine | 1963 |
[A CLINICAL TRIAL OF TEA-5D ON THE NEUROLOGICAL AND PSYCHIATRIC DISORDERS].
Topics: Amyotrophic Lateral Sclerosis; Catatonia; Erectile Dysfunction; Fatigue; Hemiplegia; Humans; Male; M | 1964 |
[ETIOLOGY OF ASTHENOPIA AND ITS TREATMENT].
Topics: Accommodation, Ocular; Adenosine Triphosphate; Asthenopia; Corneal Dystrophies, Hereditary; Eye; Eye | 1964 |
[DIAGNOSIS OF DIABETIC NEUROPATHIES. CLINICAL ASPECTS].
Topics: Autonomic Nervous System Diseases; Diabetic Neuropathies; Fatigue; Humans; Hypoglycemic Agents; Insu | 1964 |
[Effect of thiamine tetrahydrofurfuryl disulfide administration on the fatigue of workers].
Topics: Fatigue; Fursultiamin; Humans; Thiamine | 1962 |
The effect of a high fat diet on pyruvate decarboxylase deficiency without central nervous system involvement.
Topics: Carboxy-Lyases; Child; Dietary Fats; Electroencephalography; Fatigue; Fibroblasts; Humans; Male; Phy | 1983 |
[Pilot's fatigue].
Topics: Aerospace Medicine; Amino Acids; Atmospheric Pressure; Dyspepsia; Fatigue; Glutamates; Headache; Hum | 1974 |
Biological and pharmacological properties of thiamine monophosphate disulfide.
Topics: Animals; Anura; Blood Pressure; Coronary Vessels; Dogs; Fatigue; In Vitro Techniques; Intestine, Sma | 1966 |