thiamine has been researched along with Inflammation in 25 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects induced by thiamine and riboflavin, isolated or in association with corticosteroids, in models of chronic inflammation are not known." | 7.85 | Thiamine and riboflavin inhibit production of cytokines and increase the anti-inflammatory activity of a corticosteroid in a chronic model of inflammation induced by complete Freund's adjuvant. ( Bertollo, CM; Brito, AMS; Coelho, MM; Coura, GME; Godin, AM; Machado, RR; Melo, ISF; Menezes, RR; Paulino, TP; Rachid, MA; Rodrigues, FF, 2017) |
| "The effects induced by thiamine and riboflavin, isolated or in association with corticosteroids, in models of chronic inflammation are not known." | 3.85 | Thiamine and riboflavin inhibit production of cytokines and increase the anti-inflammatory activity of a corticosteroid in a chronic model of inflammation induced by complete Freund's adjuvant. ( Bertollo, CM; Brito, AMS; Coelho, MM; Coura, GME; Godin, AM; Machado, RR; Melo, ISF; Menezes, RR; Paulino, TP; Rachid, MA; Rodrigues, FF, 2017) |
| "Patients with type 2 diabetes and urinary albumin excretion in the high-normal and microalbuminuric range (15-300 mg/24h) were randomized to receive benfotiamine (n = 39) or placebo (n = 43)." | 2.77 | Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy. ( Alkhalaf, A; Bakker, SJ; Bilo, HJ; Gans, RO; Groenier, KH; Heeringa, P; Kleefstra, N; Navis, GJ; Schalkwijk, CG; Scheijen, JL, 2012) |
| "Clinicopathological characteristics, frailty assessment, biochemical and micronutrient laboratory results were recorded." | 1.91 | The relationship between micronutrient status, frailty, systemic inflammation, and clinical outcomes in patients admitted to hospital with COVID-19. ( Barbour, K; Brice, K; Catchpole, A; Goodall, E; Kelliher, T; Kemp, O; Maguire, D; McGovern, J; McMillan, DC; McPhillips, S; Melaugh, T; Moffitt, P; Murray, E; Richards, C; Robinson, S; Talwar, D; Wadsworth, J, 2023) |
| "Neuroinflammation is caused due to the activation of microglia along with pro-inflammatory cytokines." | 1.91 | Neuroprotective effects of vitamin B1 on memory impairment and suppression of pro-inflammatory cytokines in traumatic brain injury. ( Ali, Y; Amin, Z; Husn, M; Kanwal, L; Sabir, K; Shah, SA; Shah, SF, 2023) |
| "This retrospective study included 132 polytrauma patients admitted to the ICU-CA between January 2013 and December 2014." | 1.43 | Modulation of the Redox Expression and Inflammation Response in the Critically Ill Polytrauma Patient with Thoracic Injury. Statistical Correlations between Antioxidant Therapy. ( Bedreag, OH; Cradigati, CA; Dumache, R; Horhat, FG; Luca, L; Papurica, M; Popovici, SE; Rogobete, AF; Sandesc, D; Sarandan, M; Sima, LV; Vernic, C, 2016) |
| "Thiamine deficiency was highly prevalent in all groups, whereas low vitamin B₁₂ and elevated methylmalonic acid were rare." | 1.42 | Vitamin B status in patients with type 2 diabetes mellitus with and without incipient nephropathy. ( Bangert, V; Hostalek, U; Kaiser, RP; Nix, WA; Obeid, R; Schilling, M; Zirwes, R, 2015) |
| "One hundred and fifteen patients with type 2 diabetes with and without microalbuminuria or albuminuria and 39 healthy people were recruited." | 1.38 | Disturbance of B-vitamin status in people with type 2 diabetes in Indonesia--link to renal status, glycemic control and vascular inflammation. ( Adaikalakoteswari, A; Adam, JM; Kariadi, SH; Rabbani, N; Thornalley, PJ; Tjokroprawiro, A; Waspadji, S, 2012) |
| "Neuropathic pain was induced by either ligation of left L5/L6 spinal nerves or administration of streptozotocin (50 mg/kg, i." | 1.33 | Benfotiamine relieves inflammatory and neuropathic pain in rats. ( Caram-Salas, NL; Granados-Soto, V; Medina-Santillán, R; Reyes-García, G; Rocha-González, HI; Sánchez-Ramírez, GM; Vidal-Cantú, GC, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 12 (48.00) | 24.3611 |
| 2020's | 6 (24.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vitali, R | 1 |
| Prioreschi, C | 1 |
| Lorenzo Rebenaque, L | 1 |
| Colantoni, E | 1 |
| Giovannini, D | 1 |
| Frusciante, S | 1 |
| Diretto, G | 1 |
| Marco-Jiménez, F | 1 |
| Mancuso, M | 1 |
| Casciati, A | 1 |
| Pazzaglia, S | 1 |
| McGovern, J | 1 |
| Wadsworth, J | 1 |
| Catchpole, A | 2 |
| Richards, C | 1 |
| McMillan, DC | 3 |
| Kelliher, T | 1 |
| Goodall, E | 1 |
| Murray, E | 1 |
| Melaugh, T | 1 |
| McPhillips, S | 1 |
| Brice, K | 1 |
| Barbour, K | 1 |
| Robinson, S | 1 |
| Moffitt, P | 1 |
| Kemp, O | 1 |
| Talwar, D | 3 |
| Maguire, D | 2 |
| Husn, M | 1 |
| Amin, Z | 1 |
| Ali, Y | 1 |
| Kanwal, L | 1 |
| Sabir, K | 1 |
| Shah, SA | 1 |
| Shah, SF | 1 |
| Lewis, CA | 1 |
| Osland, EJ | 1 |
| de Jersey, S | 1 |
| Hopkins, G | 1 |
| Seymour, M | 1 |
| Webb, L | 1 |
| Chatfield, MD | 1 |
| Hickman, IJ | 1 |
| Riyapa, D | 1 |
| Rinchai, D | 1 |
| Muangsombut, V | 1 |
| Wuttinontananchai, C | 1 |
| Toufiq, M | 1 |
| Chaussabel, D | 1 |
| Ato, M | 1 |
| Blackwell, JM | 1 |
| Korbsrisate, S | 1 |
| Djedovic, N | 1 |
| Božić, I | 1 |
| Miljković, Đ | 1 |
| Lavrnja, I | 1 |
| Sheerins, O | 1 |
| Burns, A | 1 |
| Blyth, M | 1 |
| Shaw, A | 1 |
| Jones, B | 1 |
| Drury, C | 1 |
| Harten, J | 1 |
| Smith, I | 1 |
| Ghashut, RA | 1 |
| Kinsella, J | 1 |
| Andersen, LW | 1 |
| Liu, X | 1 |
| Montissol, S | 1 |
| Holmberg, MJ | 1 |
| Fabian-Jessing, BK | 1 |
| Donnino, MW | 1 |
| Menezes, RR | 1 |
| Godin, AM | 1 |
| Rodrigues, FF | 1 |
| Coura, GME | 1 |
| Melo, ISF | 1 |
| Brito, AMS | 1 |
| Bertollo, CM | 1 |
| Paulino, TP | 1 |
| Rachid, MA | 1 |
| Machado, RR | 1 |
| Coelho, MM | 1 |
| Lonsdale, D | 1 |
| Nix, WA | 1 |
| Zirwes, R | 1 |
| Bangert, V | 1 |
| Kaiser, RP | 1 |
| Schilling, M | 1 |
| Hostalek, U | 1 |
| Obeid, R | 1 |
| Mouton-Liger, F | 1 |
| Rebillat, AS | 1 |
| Gourmaud, S | 1 |
| Paquet, C | 1 |
| Leguen, A | 1 |
| Dumurgier, J | 1 |
| Bernadelli, P | 1 |
| Taupin, V | 1 |
| Pradier, L | 1 |
| Rooney, T | 1 |
| Hugon, J | 1 |
| Bedreag, OH | 1 |
| Rogobete, AF | 1 |
| Sandesc, D | 1 |
| Cradigati, CA | 1 |
| Sarandan, M | 1 |
| Popovici, SE | 1 |
| Dumache, R | 1 |
| Horhat, FG | 1 |
| Vernic, C | 1 |
| Sima, LV | 1 |
| Luca, L | 1 |
| Papurica, M | 1 |
| Corcoran, TB | 1 |
| O'Neill, MP | 1 |
| Webb, SA | 1 |
| Ho, KM | 1 |
| González-Ortiz, M | 1 |
| Martínez-Abundis, E | 1 |
| Robles-Cervantes, JA | 1 |
| Ramírez-Ramírez, V | 1 |
| Ramos-Zavala, MG | 1 |
| Shoeb, M | 1 |
| Ramana, KV | 1 |
| Adaikalakoteswari, A | 1 |
| Rabbani, N | 1 |
| Waspadji, S | 1 |
| Tjokroprawiro, A | 1 |
| Kariadi, SH | 1 |
| Adam, JM | 1 |
| Thornalley, PJ | 1 |
| Alkhalaf, A | 1 |
| Kleefstra, N | 1 |
| Groenier, KH | 1 |
| Bilo, HJ | 1 |
| Gans, RO | 1 |
| Heeringa, P | 1 |
| Scheijen, JL | 1 |
| Schalkwijk, CG | 1 |
| Navis, GJ | 1 |
| Bakker, SJ | 1 |
| ARIAS, SJ | 1 |
| Sánchez-Ramírez, GM | 1 |
| Caram-Salas, NL | 1 |
| Rocha-González, HI | 1 |
| Vidal-Cantú, GC | 1 |
| Medina-Santillán, R | 1 |
| Reyes-García, G | 1 |
| Granados-Soto, V | 1 |
| Chukichev, EM | 1 |
| Safrazbekian, RR | 1 |
| Apoian, NA | 1 |
| Sukasian, RS | 1 |
| Arzanunts, EM | 1 |
| Morgan, KT | 1 |
| Til, HP | 1 |
| Feron, VJ | 1 |
| De Groot, AP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Relation Between Acute Changes in the Systemic Inflammatory Response, Thiamine and Magnesium Concentrations and Transketolase Activity After Elective Knee Arthroplasty.[NCT03554668] | 47 participants (Actual) | Observational | 2018-01-15 | Completed | |||
| The Vitamin B Status in Type 2 Diabetes (VITA) Study[NCT03447275] | 174 participants (Actual) | Observational | 2011-01-31 | Completed | |||
| Safety and Efficacy of De-Novo Algorithm and Formula in the Treatment of Patients With Intractable Chronic Craniofacial Neuralgia, or Chronic Migraine Headaches.[NCT03220113] | Phase 1/Phase 2 | 100 participants (Anticipated) | Interventional | 2017-07-01 | Recruiting | ||
| A Double-Blind Clinical Trial of Benfotiamine Treatment in Diabetic Nephropathy[NCT00565318] | Phase 4 | 86 participants (Anticipated) | Interventional | 2007-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for thiamine and Inflammation
| Article | Year |
|---|---|
Cytochrome c in patients undergoing coronary artery bypass grafting: A post hoc analysis of a randomized trial.
Topics: Aged; Biomarkers; Cardiopulmonary Bypass; Coronary Artery Bypass; Cytochromes c; Double-Blind Method | 2017 |
Effect of thiamine administration on metabolic profile, cytokines and inflammatory markers in drug-naïve patients with type 2 diabetes.
Topics: Adult; Aged; Biomarkers; Blood Glucose; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Cyto | 2011 |
Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy.
Topics: Aged; Biomarkers; Cell Adhesion Molecules; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Endoth | 2012 |
22 other studies available for thiamine and Inflammation
| Article | Year |
|---|---|
Gut-Brain Axis: Insights from Hippocampal Neurogenesis and Brain Tumor Development in a Mouse Model of Experimental Colitis Induced by Dextran Sodium Sulfate.
Topics: Amino Acids; Animals; Brain Neoplasms; Brain-Gut Axis; Carcinogenesis; Colitis; Colon; Cytokines; De | 2022 |
The relationship between micronutrient status, frailty, systemic inflammation, and clinical outcomes in patients admitted to hospital with COVID-19.
Topics: COVID-19; Female; Frailty; Hospitals; Humans; Inflammation; Male; Micronutrients; Retrospective Stud | 2023 |
Neuroprotective effects of vitamin B1 on memory impairment and suppression of pro-inflammatory cytokines in traumatic brain injury.
Topics: Animals; Brain Injuries, Traumatic; Cytokines; Disease Models, Animal; Inflammation; Memory Disorder | 2023 |
Monitoring for micronutrient deficiency after bariatric surgery-what is the risk?
Topics: Bariatric Surgery; Gastric Bypass; Humans; Inflammation; Malnutrition; Micronutrients; Obesity, Morb | 2023 |
Transketolase and vitamin B1 influence on ROS-dependent neutrophil extracellular traps (NETs) formation.
Topics: Extracellular Traps; Humans; Inflammation; Neutrophils; Reactive Oxygen Species; Thiamine; Transketo | 2019 |
Benfotiamine Reduces Dendritic Cell Inflammatory Potency.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Dendritic Cells; Inflammation; Inflammation Medi | 2021 |
The relation between acute changes in the systemic inflammatory response and circulating thiamine and magnesium concentrations after elective knee arthroplasty.
Topics: Adult; Aged; Arthroplasty, Replacement, Knee; Elective Surgical Procedures; Erythrocytes; Female; Hu | 2021 |
Erythrocyte concentrations of B1, B2, B6 but not plasma C and E are reliable indicators of nutrition status in the presence of systemic inflammation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ascorbic Acid; Biomarkers; Erythrocytes; Female; Humans; | 2017 |
Thiamine and riboflavin inhibit production of cytokines and increase the anti-inflammatory activity of a corticosteroid in a chronic model of inflammation induced by complete Freund's adjuvant.
Topics: Animals; Anti-Inflammatory Agents; Chronic Disease; Cytokines; Dexamethasone; Drug Therapy, Combinat | 2017 |
Thiamin and protein folding.
Topics: alpha 1-Antitrypsin; Animals; Brain; Genetic Predisposition to Disease; Glycoproteins; Humans; Infla | 2019 |
Vitamin B status in patients with type 2 diabetes mellitus with and without incipient nephropathy.
Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Biomarkers; Case-Control Studies; Diabetes Mellitus, Ty | 2015 |
PKR downregulation prevents neurodegeneration and β-amyloid production in a thiamine-deficient model.
Topics: Amyloid; Amyloid beta-Peptides; Animals; Brain; Caspase 3; Disease Models, Animal; Down-Regulation; | 2015 |
Modulation of the Redox Expression and Inflammation Response in the Critically Ill Polytrauma Patient with Thoracic Injury. Statistical Correlations between Antioxidant Therapy.
Topics: Abbreviated Injury Scale; Acetylcysteine; Adult; Aged; Antioxidants; Ascorbic Acid; Critical Illness | 2016 |
Inflammation, vitamin deficiencies and organ failure in critically ill patients.
Topics: Adult; Aged; APACHE; Avitaminosis; Biomarkers; C-Reactive Protein; Cohort Studies; Critical Illness; | 2009 |
Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Cell Adhesion; Cell Death; Cell Line; Cyclooxyg | 2012 |
Disturbance of B-vitamin status in people with type 2 diabetes in Indonesia--link to renal status, glycemic control and vascular inflammation.
Topics: Albuminuria; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Indonesia; In | 2012 |
[Fatal case of vitamin B1 sensibilization].
Topics: Humans; Inflammation; Thiamine | 1951 |
Benfotiamine relieves inflammatory and neuropathic pain in rats.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Diabetes Mellitus, Experimental; Dose-Respons | 2006 |
[Combined action of penicillin, levomycetin and some water-soluble vitamins on aseptic inflammation and phagocytosis].
Topics: Animals; Ascorbic Acid; Chloramphenicol; Drug Synergism; Female; Folic Acid; Inflammation; Male; Nia | 1966 |
[Certain pharmacological properties of ti-iodine].
Topics: Animals; Drug Combinations; Hindlimb; Inflammation; Iodides; Paralysis; Rats; Thiamine | 1974 |
An ultrastructural study of ovine polio-encephalomalacia.
Topics: Animals; Blood Proteins; Cerebral Cortex; Cytoplasmic Granules; Edema; Encephalomalacia; Endothelium | 1973 |
The toxicity of sulphite. I. Long-term feeding and multigeneration studies in rats.
Topics: Anemia; Animals; Diet; Feces; Feeding Behavior; Female; Growth; Hematopoiesis; Inflammation; Kidney; | 1972 |