thiamine has been researched along with Idiopathic Parkinson Disease in 9 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the potential clinical, restorative, and neuroprotective effects of long-term treatment with thiamine in Parkinson disease (PD)." | 7.81 | Long-Term Treatment with High-Dose Thiamine in Parkinson Disease: An Open-Label Pilot Study. ( Cardelli, LE; Colangeli, M; Costantini, A; Fancellu, R; Grossi, E; Jenner, C; Mondonico, S; Pala, MI; Proietti, S, 2015) |
| "To investigate the potential clinical, restorative, and neuroprotective effects of long-term treatment with thiamine in Parkinson disease (PD)." | 3.81 | Long-Term Treatment with High-Dose Thiamine in Parkinson Disease: An Open-Label Pilot Study. ( Cardelli, LE; Colangeli, M; Costantini, A; Fancellu, R; Grossi, E; Jenner, C; Mondonico, S; Pala, MI; Proietti, S, 2015) |
| "Thiamine has also been implicated in PD through its effects on L-type voltage-sensitive calcium channels (L-VSCC), matrix metalloproteinases (MMPs), prostaglandins (PGs), cyclooxygenase-2 (COX-2), reactive oxygen species (ROS), and nitric oxide synthase (NOS)." | 2.48 | Thiamine and Parkinson's disease. ( Lu'o'ng, Kv; Nguyên, LT, 2012) |
| "We performed the Unified Parkinson's Disease Rating Scale (UPDRS) and started a parenteral therapy with high doses of thiamine." | 1.39 | High-dose thiamine as initial treatment for Parkinson's disease. ( Colangeli, M; Compagnoni, L; Costantini, A; Pala, MI, 2013) |
| "Thiamine is an essential cofactor for several important enzymes involved in brain oxidative metabolism, such as the alpha-ketoglutarate dehydrogenase complex (KGDHC), pyruvate-dehydrogenase complex, and transketolase." | 1.30 | Cerebrospinal fluid levels of thiamine in patients with Parkinson's disease. ( Barcenilla, B; Berbel, A; de Bustos, F; Fernández-Vivancos, E; Gómez-Escalonilla, C; Hernánz, A; Jiménez-Jiménez, FJ; Molina, JA; Villanueva, C; Zurdo, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Håglin, L | 1 |
| Domellöf, M | 1 |
| Bäckman, L | 1 |
| Forsgren, L | 1 |
| Luong, KV | 1 |
| Nguyễn, LT | 2 |
| Costantini, A | 2 |
| Pala, MI | 2 |
| Compagnoni, L | 1 |
| Colangeli, M | 2 |
| Grossi, E | 1 |
| Mondonico, S | 1 |
| Cardelli, LE | 1 |
| Jenner, C | 1 |
| Proietti, S | 1 |
| Fancellu, R | 1 |
| Santos-García, D | 1 |
| Macías, M | 1 |
| Llaneza, M | 1 |
| Grande, M | 1 |
| de la Fuente-Fernández, R | 1 |
| Lu'o'ng, Kv | 1 |
| Balk, E | 1 |
| Chung, M | 1 |
| Raman, G | 1 |
| Tatsioni, A | 1 |
| Chew, P | 1 |
| Ip, S | 1 |
| DeVine, D | 1 |
| Lau, J | 1 |
| Gold, M | 1 |
| Hauser, RA | 1 |
| Chen, MF | 1 |
| Jiménez-Jiménez, FJ | 1 |
| Molina, JA | 1 |
| Hernánz, A | 1 |
| Fernández-Vivancos, E | 1 |
| de Bustos, F | 1 |
| Barcenilla, B | 1 |
| Gómez-Escalonilla, C | 1 |
| Zurdo, M | 1 |
| Berbel, A | 1 |
| Villanueva, C | 1 |
3 reviews available for thiamine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
The beneficial role of thiamine in Parkinson disease.
Topics: Animals; Humans; Parkinson Disease; Signal Transduction; Thiamine; Vitamins | 2013 |
Thiamine and Parkinson's disease.
Topics: Animals; Biomarkers; Cyclooxygenase 2; Humans; Oxidative Stress; Parkinson Disease; Reactive Oxygen | 2012 |
B vitamins and berries and age-related neurodegenerative disorders.
Topics: Aging; Alzheimer Disease; Animals; Blueberry Plants; Cognition; Disease Models, Animal; Folic Acid; | 2006 |
6 other studies available for thiamine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Low plasma thiamine and phosphate in male patients with Parkinson's disease is associated with mild cognitive impairment.
Topics: Case-Control Studies; Cognitive Dysfunction; Female; Humans; Male; Parkinson Disease; Phosphates; Th | 2020 |
High-dose thiamine as initial treatment for Parkinson's disease.
Topics: Aged; Female; Humans; Male; Parkinson Disease; Thiamine; Treatment Outcome; Vitamin B Complex | 2013 |
Long-Term Treatment with High-Dose Thiamine in Parkinson Disease: An Open-Label Pilot Study.
Topics: Aged; Antiparkinson Agents; Disease Management; Dose-Response Relationship, Drug; Humans; Male; Midd | 2015 |
Serum vitamin B(12) and folate levels in Parkinson's disease patients treated with duodenal levodopa infusion.
Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Humans; Infusions, Parenteral; Levodopa; Male; Middl | 2011 |
Plasma thiamine deficiency associated with Alzheimer's disease but not Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Female; Humans; Male; Middle Aged; Parkinson Dise | 1998 |
Cerebrospinal fluid levels of thiamine in patients with Parkinson's disease.
Topics: Antiparkinson Agents; Dopamine Agonists; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Dise | 1999 |