thiamine has been researched along with Genetic Predisposition in 12 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Novel strategies were coupled to position a new hypertension-susceptibility locus, uncovering a previously unsuspected thiamine transporter whose genetic variants predicted several disturbances in cardiac and autonomic function." | 7.80 | Genetic implication of a novel thiamine transporter in human hypertension. ( Corneveaux, JJ; Ehret, GB; Eskin, E; Hightower, CM; Huentelman, MJ; Mahata, M; Maihofer, AX; Miramontes-Gonzalez, JP; Nievergelt, CM; O'Connor, DT; Pastinen, T; Rao, F; Saier, MH; Schork, AJ; Schork, NJ; Sun, EI; Waalen, J; Wei, Z; Zhang, K, 2014) |
| "Novel strategies were coupled to position a new hypertension-susceptibility locus, uncovering a previously unsuspected thiamine transporter whose genetic variants predicted several disturbances in cardiac and autonomic function." | 3.80 | Genetic implication of a novel thiamine transporter in human hypertension. ( Corneveaux, JJ; Ehret, GB; Eskin, E; Hightower, CM; Huentelman, MJ; Mahata, M; Maihofer, AX; Miramontes-Gonzalez, JP; Nievergelt, CM; O'Connor, DT; Pastinen, T; Rao, F; Saier, MH; Schork, AJ; Schork, NJ; Sun, EI; Waalen, J; Wei, Z; Zhang, K, 2014) |
| "This relation could be modified by genetic susceptibility, particularly related to the C3 genotype." | 2.82 | Dietary folate, B vitamins, genetic susceptibility and progression to advanced nonexudative age-related macular degeneration with geographic atrophy: a prospective cohort study. ( Merle, BM; Rosner, B; Seddon, JM; Silver, RE, 2016) |
| "PDHc deficiency was demonstrated in muscle and fibroblasts without detectable PDHA1 mutations." | 1.36 | Dihydrolipoamide dehydrogenase (DLD) deficiency in a Spanish patient with myopathic presentation due to a new mutation in the interface domain. ( Briones, P; Font, A; Pineda, M; Quintana, E; Ribes, A; Tort, F; Vilaseca, MA, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 10 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bottega, R | 1 |
| Perrone, MD | 1 |
| Vecchiato, K | 1 |
| Taddio, A | 1 |
| Sabui, S | 1 |
| Pecile, V | 1 |
| Said, HM | 1 |
| Faletra, F | 1 |
| Lonsdale, D | 1 |
| Zhang, K | 1 |
| Huentelman, MJ | 1 |
| Rao, F | 1 |
| Sun, EI | 1 |
| Corneveaux, JJ | 1 |
| Schork, AJ | 1 |
| Wei, Z | 1 |
| Waalen, J | 1 |
| Miramontes-Gonzalez, JP | 1 |
| Hightower, CM | 1 |
| Maihofer, AX | 1 |
| Mahata, M | 1 |
| Pastinen, T | 1 |
| Ehret, GB | 1 |
| Schork, NJ | 1 |
| Eskin, E | 1 |
| Nievergelt, CM | 1 |
| Saier, MH | 1 |
| O'Connor, DT | 1 |
| Gupta, A | 1 |
| Thelma, BK | 1 |
| Flønes, I | 1 |
| Sztromwasser, P | 1 |
| Haugarvoll, K | 1 |
| Dölle, C | 1 |
| Lykouri, M | 1 |
| Schwarzlmüller, T | 1 |
| Jonassen, I | 1 |
| Miletic, H | 1 |
| Johansson, S | 1 |
| Knappskog, PM | 1 |
| Bindoff, LA | 1 |
| Tzoulis, C | 1 |
| Merle, BM | 1 |
| Silver, RE | 1 |
| Rosner, B | 1 |
| Seddon, JM | 1 |
| Barnerias, C | 1 |
| Saudubray, JM | 1 |
| Touati, G | 1 |
| De Lonlay, P | 1 |
| Dulac, O | 1 |
| Ponsot, G | 1 |
| Marsac, C | 1 |
| Brivet, M | 1 |
| Desguerre, I | 1 |
| Debs, R | 1 |
| Depienne, C | 1 |
| Rastetter, A | 1 |
| Bellanger, A | 1 |
| Degos, B | 1 |
| Galanaud, D | 1 |
| Keren, B | 1 |
| Lyon-Caen, O | 1 |
| Brice, A | 1 |
| Sedel, F | 1 |
| Bai, CH | 1 |
| Chen, JR | 1 |
| Chiu, HC | 1 |
| Chou, CC | 1 |
| Chau, LY | 1 |
| Pan, WH | 1 |
| Quintana, E | 1 |
| Pineda, M | 1 |
| Font, A | 1 |
| Vilaseca, MA | 1 |
| Tort, F | 1 |
| Ribes, A | 1 |
| Briones, P | 1 |
| Heap, LC | 1 |
| Pratt, OE | 1 |
| Ward, RJ | 1 |
| Waller, S | 1 |
| Thomson, AD | 1 |
| Shaw, GK | 1 |
| Peters, TJ | 1 |
| Syska, E | 1 |
| Schmidt, R | 1 |
| Schubert, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Age-Related Eye Disease Study (AREDS) and AREDS2 Follow-Up[NCT00594672] | 110 participants (Actual) | Observational | 2008-06-02 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for thiamine and Genetic Predisposition
| Article | Year |
|---|---|
Dietary folate, B vitamins, genetic susceptibility and progression to advanced nonexudative age-related macular degeneration with geographic atrophy: a prospective cohort study.
Topics: Aged; Body Mass Index; Collagen Type VIII; Complement C2; Complement C3; Complement Factor B; Comple | 2016 |
11 other studies available for thiamine and Genetic Predisposition
| Article | Year |
|---|---|
Functional analysis of the third identified SLC25A19 mutation causative for the thiamine metabolism dysfunction syndrome 4.
Topics: Adolescent; Brain Diseases; Genetic Predisposition to Disease; Humans; Male; Microcephaly; Mitochond | 2019 |
Thiamin and protein folding.
Topics: alpha 1-Antitrypsin; Animals; Brain; Genetic Predisposition to Disease; Glycoproteins; Humans; Infla | 2019 |
Genetic implication of a novel thiamine transporter in human hypertension.
Topics: Adult; Alleles; Blood Pressure; DNA; Female; Genetic Predisposition to Disease; Genome-Wide Associat | 2014 |
Identification of critical variants within SLC44A4, an ulcerative colitis susceptibility gene identified in a GWAS in north Indians.
Topics: Animals; CHO Cells; Colitis, Ulcerative; Cricetulus; Exons; Gene Expression; Genetic Predisposition | 2016 |
Novel SLC19A3 Promoter Deletion and Allelic Silencing in Biotin-Thiamine-Responsive Basal Ganglia Encephalopathy.
Topics: 5' Untranslated Regions; Adolescent; Alleles; Basal Ganglia; Basal Ganglia Diseases; Biotin; Brain; | 2016 |
Pyruvate dehydrogenase complex deficiency: four neurological phenotypes with differing pathogenesis.
Topics: Adolescent; Brain; Female; Genetic Predisposition to Disease; Humans; Longitudinal Studies; Magnetic | 2010 |
Biotin-responsive basal ganglia disease in ethnic Europeans with novel SLC19A3 mutations.
Topics: Adult; Basal Ganglia; Basal Ganglia Diseases; Biotin; Brain Diseases, Metabolic; DNA Mutational Anal | 2010 |
Shorter GT repeat polymorphism in the heme oxygenase-1 gene promoter has protective effect on ischemic stroke in dyslipidemia patients.
Topics: Cholesterol, HDL; Dyslipidemias; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype | 2010 |
Dihydrolipoamide dehydrogenase (DLD) deficiency in a Spanish patient with myopathic presentation due to a new mutation in the interface domain.
Topics: Acidosis, Lactic; Adult; Amino Acid Sequence; Base Sequence; Biomarkers; Blepharoptosis; Cells, Cult | 2010 |
Individual susceptibility to Wernicke-Korsakoff syndrome and alcoholism-induced cognitive deficit: impaired thiamine utilization found in alcoholics and alcohol abusers.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Brain Damage, Chronic; Cognition Disorders; Genetic Predi | 2002 |
The time of palatal fusion in mice: a factor of strain susceptibility to teratogens.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Genetic Predisposition to Disease; Gestational A | 2004 |