Page last updated: 2024-10-20

thiamine and Folic Acid Deficiency

thiamine has been researched along with Folic Acid Deficiency in 21 studies

thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.

Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)

Research Excerpts

ExcerptRelevanceReference
" A diagnosis of beriberi heart disease was made because of thiamine deficiency."3.75[Case of Wernicke's encephalopathy and subacute combined degeneration of the spinal cord due to vitamin deficiency showing changes in the bilateral corpus striatum and cardiac arrest due to beriberi heart disease]. ( Ishiko, T; Nanri, K; Saito, H; Taguchi, T; Takeguchi, M, 2009)
"Despite guidelines and recommendations, Wernicke's encephalopathy (WE) treatment lacks evidence, leading to clinical practice variability."1.91Treatment variability and its relationships to outcomes among patients with Wernicke's encephalopathy: A multicenter retrospective study. ( Alvela-Suárez, L; Antolí-Royo, AC; Antúnez-Jorge, E; Castro, J; Chamorro, AJ; Felipe-Pérez, NC; Fernández-Rial, Á; Fernández-Rodríguez, CM; Fernández-Solá, J; Fidalgo-Navarro, A; Gomila-Grange, A; López-Castro, J; Machado-Prieto, B; Marcos, M; Martín-González, MC; Mateos-Díaz, AM; Medina-García, JA; Monte-Secades, R; Muga, R; Novo-Veleiro, I; Polvorosa-Gómez, MA; Prada-González, C; Puerta-Louro, R; Rosón-Hernández, B; Sabio-Repiso, P; Sanvisens-Bergé, A; Seco-Hernández, E; Suárez-Cuervo, C; Valle-Sánchez, MD; Vázquez-Vigo, R, 2023)
"Body weight was under 90% of the ideal in 8/33 (24%) patients."1.30Nutritional deficiencies in chronic alcoholics: relation to dietary intake and alcohol consumption. ( Camilo, ME; Cardoso, JN; Cravo, M; Glória, L; Leitão, CN; Mira, FC; Oliveira, AG; Resende, M, 1997)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199011 (52.38)18.7374
1990's3 (14.29)18.2507
2000's3 (14.29)29.6817
2010's3 (14.29)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Novo-Veleiro, I1
Mateos-Díaz, AM1
Rosón-Hernández, B1
Medina-García, JA1
Muga, R1
Fernández-Solá, J1
Martín-González, MC1
Seco-Hernández, E1
Suárez-Cuervo, C1
Monte-Secades, R1
Machado-Prieto, B1
Puerta-Louro, R1
Prada-González, C1
Fernández-Rial, Á1
Sabio-Repiso, P1
Vázquez-Vigo, R1
Antolí-Royo, AC1
Gomila-Grange, A1
Felipe-Pérez, NC1
Sanvisens-Bergé, A1
Antúnez-Jorge, E1
Fernández-Rodríguez, CM1
Alvela-Suárez, L1
Fidalgo-Navarro, A1
Castro, J1
Polvorosa-Gómez, MA1
Valle-Sánchez, MD1
López-Castro, J1
Chamorro, AJ1
Marcos, M1
Gunanti, IR1
Marks, GC1
Al-Mamun, A1
Long, KZ1
Ortigoza Escobar, JD1
Pérez Dueñas, B1
Ishiko, T1
Taguchi, T1
Takeguchi, M1
Saito, H1
Nanri, K1
Sun, A1
Lin, HP1
Wang, YP1
Chen, HM1
Cheng, SJ1
Chiang, CP1
Leevy, CM2
Baker, H2
Tenhove, W1
Frank, O2
Cherrick, GR1
Bruno, EJ1
Ziegenfuss, TN1
Kamien, M1
Bachevalier, J1
Joyal, C1
Botez, MI1
Glória, L1
Cravo, M1
Camilo, ME1
Resende, M1
Cardoso, JN1
Oliveira, AG1
Leitão, CN1
Mira, FC1
Fukatsu, R1
Tamura, T1
Miyachi, T1
Noda, K1
Watanabe, C1
Katayama, S1
Kaseda, Y1
Nakamura, S1
Goldsmith, GA1
Zetterman, RK1
Rajan, KS1
ten Hove, W1
Bell, IR1
Morrow, FD1
Read, M1
Berkes, S1
Perrone, G1
Boeschoten, EW1
Schrijver, J1
Krediet, RT1
Schreurs, WH1
Arisz, L1
Walzem, RL1
Clifford, AJ1
Blair, R1
Newsome, F1
Cohen, C1
Howard, L1
Wagner, C1
Schenker, S1
Gatto, I1
Bamji, MS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Study on the Treatment of Burning Mouth Syndrome With Integration of Traditional Chinese Medicine(TCM) and Western Medicine Based on TCM Syndrome Differentiation[NCT04189367]Phase 380 participants (Anticipated)Interventional2020-06-20Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for thiamine and Folic Acid Deficiency

ArticleYear
Treatable Inborn Errors of Metabolism Due to Membrane Vitamin Transporters Deficiency.
    Seminars in pediatric neurology, 2016, Volume: 23, Issue:4

    Topics: Child, Preschool; Folic Acid; Folic Acid Deficiency; Humans; Infant; Infant, Newborn; Membrane Trans

2016
Water-soluble vitamins: research update.
    Current sports medicine reports, 2005, Volume: 4, Issue:4

    Topics: Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Neural T

2005
Vitamin B complex. Thiamine, riboflavin, niacin, folic acid (folacin), vitamin B12, biotin.
    Progress in food & nutrition science, 1975, Volume: 1, Issue:9

    Topics: Adolescent; Adult; Aged; Animals; Biotin; Chemical Phenomena; Chemistry; Child; Female; Folic Acid;

1975
Involvement of water-soluble vitamins in diseases of swine.
    Journal of animal science, 1985, Volume: 60, Issue:6

    Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Biotin; Choline; Choline Deficiency; Folic Acid; F

1985
[Megaloblastic anemias in childhood].
    La Pediatria, 1970, Jul-30, Volume: 78, Issue:3

    Topics: Anemia, Macrocytic; Anemia, Pernicious; Child; Child, Preschool; Diphyllobothriasis; Female; Folic A

1970

Other Studies

16 other studies available for thiamine and Folic Acid Deficiency

ArticleYear
Treatment variability and its relationships to outcomes among patients with Wernicke's encephalopathy: A multicenter retrospective study.
    Drug and alcohol dependence, 2023, 11-01, Volume: 252

    Topics: Alcoholism; Folic Acid Deficiency; Humans; Retrospective Studies; Thiamine; Thiamine Deficiency; Wer

2023
Low serum vitamin B-12 and folate concentrations and low thiamin and riboflavin intakes are inversely associated with greater adiposity in Mexican American children.
    The Journal of nutrition, 2014, Volume: 144, Issue:12

    Topics: Adiposity; Adolescent; Body Mass Index; Child; Cross-Sectional Studies; Female; Folic Acid; Folic Ac

2014
[Case of Wernicke's encephalopathy and subacute combined degeneration of the spinal cord due to vitamin deficiency showing changes in the bilateral corpus striatum and cardiac arrest due to beriberi heart disease].
    Brain and nerve = Shinkei kenkyu no shinpo, 2009, Volume: 61, Issue:9

    Topics: Beriberi; Cardiomegaly; Corpus Striatum; Female; Folic Acid; Folic Acid Deficiency; Heart Arrest; Hu

2009
Significant reduction of serum homocysteine level and oral symptoms after different vitamin-supplement treatments in patients with burning mouth syndrome.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2013, Volume: 42, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anemia, Iron-Deficiency; Burning Mouth Syndrome; Calcium; Female; Fe

2013
B-COMPLEX VITAMINS IN LIVER DISEASE OF THE ALCOHOLIC.
    The American journal of clinical nutrition, 1965, Volume: 16

    Topics: Alcoholism; Autoradiography; Biopsy; Biotin; Blood Chemical Analysis; DNA; Drug Therapy; Fatty Liver

1965
The repeating history of objections to the fortification of bread and alcohol: from iron filings to folic acid.
    The Medical journal of Australia, 2006, Jun-19, Volume: 184, Issue:12

    Topics: Adult; Alcoholic Beverages; Australia; Bread; Child; Dissent and Disputes; Female; Folic Acid; Folic

2006
Blood thiamine and blood folate levels. A comparative study in control, alcoholic and folate-deficient subjects.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1981, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Aged; Alcoholism; Biological Assay; Erythrocytes; Female; Folic Acid; Folic Acid

1981
Nutritional deficiencies in chronic alcoholics: relation to dietary intake and alcohol consumption.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:3

    Topics: Adult; Alcohol Drinking; Alcoholism; Avitaminosis; Body Height; Body Mass Index; Body Weight; Diet;

1997
[Chronic neuropathy, a high level of protein in cerebrospinal fluid, and vitamin B1 and folate deficiency in a patient with normal-pressure hydrocephalus].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1997, Volume: 34, Issue:6

    Topics: Aged; Cerebrospinal Fluid Proteins; Chronic Disease; Female; Folic Acid Deficiency; Humans; Hydrocep

1997
Inability of chronic alcoholics with liver disease to use food as a source of folates, thiamin and vitamin B6.
    The American journal of clinical nutrition, 1975, Volume: 28, Issue:12

    Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Absorption; Liver Diseases, Alc

1975
Low thyroxine levels in female psychiatric inpatients with riboflavin deficiency: implications for folate-dependent methylation.
    Acta psychiatrica Scandinavica, 1992, Volume: 85, Issue:5

    Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Hospitalization; Humans; Male; Mental Disorders; M

1992
Deficiencies of vitamins in CAPD patients: the effect of supplementation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1988, Volume: 3, Issue:2

    Topics: Adult; Ascorbic Acid; Ascorbic Acid Deficiency; Cross-Sectional Studies; Female; Folic Acid; Folic A

1988
Thiamin absorption is not compromised in folate-deficient rats.
    The Journal of nutrition, 1988, Volume: 118, Issue:11

    Topics: Animals; Biological Transport, Active; Body Weight; Carbon Radioisotopes; Folic Acid; Folic Acid Def

1988
Social and economic factors in the nutrition of the elderly.
    The Proceedings of the Nutrition Society, 1974, Volume: 33, Issue:1

    Topics: Age Factors; Aged; Diet; Diet Fads; Female; Folic Acid Deficiency; Food Service, Hospital; Humans; I

1974
Malabsorption of thiamin in folate-deficient rats.
    The Journal of nutrition, 1974, Volume: 104, Issue:8

    Topics: Animals; Biological Transport; Biological Transport, Active; Duodenum; Erythrocytes; Folic Acid; Fol

1974
Changes in hepatic and erythrocyte transketolase activity and thiamine concentration of liver in experimental deficiency of water soluble vitamins.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1972, Volume: 42, Issue:2

    Topics: Animals; Ascorbic Acid Deficiency; Avitaminosis; Erythrocytes; Folic Acid Deficiency; Glyceraldehyde

1972