thiamine has been researched along with Familial Spastic Paraparesis, Htlv-1-Associated in 2 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was conducted to construct a basis for a therapeutic strategy against human T-lymphotropic virus type-I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) using a compound that contained a disulfide moiety, prosultiamine, which is a homologue of allithiamine originally synthesized by allicin and thiamine-thiol, for the targeting of HTLV-I-infected cells." | 5.14 | Disulfide-mediated apoptosis of human T-lymphotrophc virus type-I (HTLV-I)-infected cells in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis. ( Aramaki, T; Eguchi, K; Fukushima, N; Ida, H; Nakamura, H; Nakamura, T; Nishiura, Y, 2009) |
| "In the overactive bladder symptom score, night-time frequency, urgency and the total score improved after oral prosultiamine treatment (P = 0." | 2.87 | Prosultiamine for treatment of lower urinary tract dysfunction accompanied by human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis. ( Matsuo, T; Miyata, Y; Nakamura, T; Sakai, H; Satoh, K, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsuo, T | 1 |
| Miyata, Y | 1 |
| Nakamura, T | 2 |
| Satoh, K | 1 |
| Sakai, H | 1 |
| Nishiura, Y | 1 |
| Fukushima, N | 1 |
| Nakamura, H | 1 |
| Ida, H | 1 |
| Aramaki, T | 1 |
| Eguchi, K | 1 |
2 trials available for thiamine and Familial Spastic Paraparesis, Htlv-1-Associated
| Article | Year |
|---|---|
Prosultiamine for treatment of lower urinary tract dysfunction accompanied by human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis.
Topics: Administration, Oral; Aged; Biomarkers; Female; Human T-lymphotropic virus 1; Humans; Male; Middle A | 2018 |
Disulfide-mediated apoptosis of human T-lymphotrophc virus type-I (HTLV-I)-infected cells in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis.
Topics: Aged; Anti-HIV Agents; Apoptosis; Cell Line; Disulfides; Female; HTLV-I Infections; Human T-lymphotr | 2009 |