thiamine has been researched along with Electron Transport Chain Deficiencies, Mitochondrial in 7 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The diabetic states that associate with these genetic variants are MODY 2, thiamine responsive anaemia syndrome (TRAS) and mitochondrial diabetes." | 8.81 | Mitochondrial diabetes, diabetes and the thiamine-responsive megaloblastic anaemia syndrome and MODY-2. Diseases with common pathophysiology? ( Maassen, JA, 2002) |
| "Wolfram syndrome, Kearns-Sayre syndrome, thiamine-responsive megaloblastic anemia, and maternally inherited diabetes and deafness are genetic disorders characterized by diabetes, impaired hearing, and vision." | 5.22 | Diabetes Out-of-the-Box: Diabetes Mellitus and Impairment in Hearing and Vision. ( Gruber, N; Pinhas-Hamiel, O, 2022) |
| " The diabetic states that associate with these genetic variants are MODY 2, thiamine responsive anaemia syndrome (TRAS) and mitochondrial diabetes." | 4.81 | Mitochondrial diabetes, diabetes and the thiamine-responsive megaloblastic anaemia syndrome and MODY-2. Diseases with common pathophysiology? ( Maassen, JA, 2002) |
| "We reviewed the medical records of all patients with confirmed mitochondrial diseases treated with any or all of thiamin, riboflavin, coenzyme Q, vitamin C (approximately 10 mg/kg per day) and a high-fat diet (50-60% of caloric intake) between 1997 and 2003." | 3.72 | Effect of high-dose vitamins, coenzyme Q and high-fat diet in paediatric patients with mitochondrial diseases. ( Boneh, A; Panetta, J; Smith, LJ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Gruber, N | 1 |
| Pinhas-Hamiel, O | 1 |
| Tinsa, F | 1 |
| Hechmi, M | 1 |
| Hadj, IB | 1 |
| Khalsi, F | 1 |
| Chargui, M | 1 |
| Kefi, R | 1 |
| Azouz, H | 1 |
| Boussetta, K | 1 |
| Abdelhak, S | 1 |
| Jungtrakoon, P | 1 |
| Shirakawa, J | 1 |
| Buranasupkajorn, P | 1 |
| Gupta, MK | 1 |
| De Jesus, DF | 1 |
| Pezzolesi, MG | 1 |
| Panya, A | 1 |
| Hastings, T | 1 |
| Chanprasert, C | 1 |
| Mendonca, C | 1 |
| Kulkarni, RN | 1 |
| Doria, A | 1 |
| Maassen, JA | 1 |
| Panetta, J | 1 |
| Smith, LJ | 1 |
| Boneh, A | 1 |
| Suzuki, S | 1 |
| Kuroda, Y | 1 |
| Naito, E | 1 |
| Touda, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open Label Pilot Study Using Hydroxytyrosol (HT) as a Dietary Supplement in Patients With Mitochondrial Diseases (MDs)[NCT04543968] | 12 participants (Anticipated) | Interventional | 2022-07-05 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for thiamine and Electron Transport Chain Deficiencies, Mitochondrial
| Article | Year |
|---|---|
Diabetes Out-of-the-Box: Diabetes Mellitus and Impairment in Hearing and Vision.
Topics: Anemia, Megaloblastic; Deafness; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hearing; Hearing Loss | 2022 |
Mitochondrial diabetes, diabetes and the thiamine-responsive megaloblastic anaemia syndrome and MODY-2. Diseases with common pathophysiology?
Topics: Anemia, Megaloblastic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Mitochondrial Diseases; | 2002 |
[Role of mitochondrial dysfunction in pathogenesis of diabetic microangiopathy].
Topics: Antioxidants; Coenzymes; Diabetic Angiopathies; DNA Damage; DNA, Mitochondrial; Drug Design; Electro | 2005 |
[Drug therapy for mitochondrial diseases].
Topics: Carnitine; Coenzymes; Cytochrome c Group; Cytochromes c; Dichloroacetic Acid; Drug Combinations; Dru | 2002 |
3 other studies available for thiamine and Electron Transport Chain Deficiencies, Mitochondrial
| Article | Year |
|---|---|
Thiamine responsive megaloblastic anemia mimicking mitochondrial disorders.
Topics: Anemia, Megaloblastic; Child, Preschool; Diagnosis, Differential; Humans; Male; Mitochondrial Diseas | 2019 |
Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes.
Topics: Anemia, Megaloblastic; Cell Cycle Checkpoints; Diabetes Mellitus; Humans; Insulin; Membrane Transpor | 2019 |
Effect of high-dose vitamins, coenzyme Q and high-fat diet in paediatric patients with mitochondrial diseases.
Topics: Adolescent; Ascorbic Acid; Child; Child, Preschool; Dietary Fats; DNA, Mitochondrial; Female; Humans | 2004 |