thiamine has been researched along with Electrolytes in 27 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The initial measurement of thiamine level and serum electrolytes, including phosphate and magnesium, their supplementation if necessary, and a slow increase in nutritional intake along with close monitoring of serum electrolytes play an important role." | 4.98 | [Refeeding syndrome : Pathophysiology, risk factors, prevention, and treatment]. ( Diekmann, R; Fleiter, O; Fricke, L; Janssen, G; Kreilkamp, A; Marburger, C; Modreker, MK; Nels, S; Pourhassan, M; Schaefer, R; Volkert, D; Willschrei, HP; Wirth, R, 2018) |
| "The effect of high dietary sulfur (S) supplementation on blood thiamine (B1) concentration, biochemical indices of liver, muscle and kidney damage and selected plasma electrolytes was studied in six sheep." | 3.67 | Sulfur-induced polioencephalomalacia in sheep: some biochemical changes. ( Christensen, DA; Gooneratne, SR; Olkowski, AA, 1989) |
| "If alcoholic ketoacidosis is suspected, dextrose-containing fluids are recommended over normal saline." | 2.53 | Unpeeling the Evidence for the Banana Bag: Evidence-Based Recommendations for the Management of Alcohol-Associated Vitamin and Electrolyte Deficiencies in the ICU. ( Adkins, DA; Cook, AM; Flannery, AH, 2016) |
| "The objective of this study was to determine the relationship between glucose dosage in parenteral nutrition and reductions in levels of body thiamine in rats." | 1.51 | Influence of Glucose Dosage in Parenteral Nutrition on Body Thiamine Levels in Rats. ( Harada, D; Nakayama, M, 2019) |
| "Low thiamine levels were infrequent affecting 3/29 (10%)." | 1.40 | Refeeding syndrome is uncommon in alcoholics admitted to a hospital detoxification unit. ( Gilmour, M; Manning, S; Robinson, GM; Weatherall, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (59.26) | 18.7374 |
| 1990's | 3 (11.11) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 6 (22.22) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Bradley, C | 1 |
| Hansen, A | 1 |
| Levy, P | 1 |
| Hashim, E | 1 |
| Wirth, R | 1 |
| Diekmann, R | 1 |
| Janssen, G | 1 |
| Fleiter, O | 1 |
| Fricke, L | 1 |
| Kreilkamp, A | 1 |
| Modreker, MK | 1 |
| Marburger, C | 1 |
| Nels, S | 1 |
| Pourhassan, M | 1 |
| Schaefer, R | 1 |
| Willschrei, HP | 1 |
| Volkert, D | 1 |
| Harada, D | 1 |
| Nakayama, M | 1 |
| Manning, S | 1 |
| Gilmour, M | 1 |
| Weatherall, M | 1 |
| Robinson, GM | 1 |
| Uccello-Barretta, G | 1 |
| Balzano, F | 1 |
| Aiello, F | 1 |
| Falugiani, N | 1 |
| Desideri, I | 1 |
| Flannery, AH | 1 |
| Adkins, DA | 1 |
| Cook, AM | 1 |
| Baś, B | 1 |
| Jakubowska, M | 1 |
| Górski, Ł | 1 |
| PICCOLI, P | 1 |
| FERRARI, M | 1 |
| DANIELE, E | 1 |
| Okudaira, K | 1 |
| PECORA, LJ | 1 |
| O'Hara, TM | 1 |
| Bennett, L | 1 |
| McCoy, CP | 1 |
| Jack, SW | 1 |
| Fleming, S | 1 |
| Allwood, MC | 1 |
| Martin, H | 1 |
| Yoshino, M | 1 |
| Aoki, K | 1 |
| Akeda, H | 1 |
| Hashimoto, K | 1 |
| Ikeda, T | 1 |
| Inoue, F | 1 |
| Ito, M | 1 |
| Kawamura, M | 1 |
| Kohno, Y | 1 |
| Koga, Y | 1 |
| Kuroda, Y | 1 |
| Maesaka, H | 1 |
| Murakamisoda, H | 1 |
| Sugiyama, N | 1 |
| Suzuki, Y | 1 |
| Yano, S | 1 |
| Yoshioka, A | 1 |
| Talbott, GD | 1 |
| Schmid, F | 1 |
| Christeller, S | 1 |
| Rehm, W | 1 |
| Wysokiński, A | 1 |
| Struzak-Wysokińska, M | 1 |
| Gooneratne, SR | 1 |
| Olkowski, AA | 1 |
| Christensen, DA | 1 |
| Savina, AS | 1 |
| Dvorina, VM | 1 |
| Carstensen, JT | 1 |
| Girolami, M | 1 |
| Mizuhira, B | 1 |
| Loew, FM | 1 |
| Dunlop, RH | 1 |
| Christian, RG | 1 |
| White, JR | 1 |
| Kaim, SC | 1 |
| Caccuri, S | 1 |
| Fati, S | 1 |
| Sauli, M | 1 |
| D'Alessandro, R | 1 |
| Faelli, U | 1 |
| Violani, M | 1 |
| Bonazzi, L | 1 |
| Sireci, V | 1 |
| Franchi, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Thiamine Administration After Cardiac Surgery Trial[NCT04641104] | Phase 4 | 200 participants (Actual) | Interventional | 2020-11-20 | Completed | ||
| Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis.[NCT03422159] | Phase 2 | 140 participants (Actual) | Interventional | 2018-02-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Defined as the day 4 post-randomization SOFA score minus the initial SOFA score. The Sequential Organ Failure Assessment (SOFA) Score is a mortality prediction score that is based on the degree of dysfunction of six organ systems. The score is calculated on admission and every 24 hours until discharge using the worst parameters measured during the prior 24 hours SOFA score ranges from 0 (no organ dysfunction) to 24 (highest possible score / organ dysfunction). (NCT03422159)
Timeframe: 4 days post-randomization
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Arm | 2.9 |
| Placebo Arm | 1.93 |
Time from admitting to discharge of hospital stay. (NCT03422159)
Timeframe: From admission to the hospital until final discharge, up to 28 days.
| Intervention | Days (Mean) |
|---|---|
| Treatment Arm | 11.5 |
| Placebo Arm | 11 |
In-hospital mortality rate. (NCT03422159)
Timeframe: Survival until hospital discharge, up to 28 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment Arm | 11 |
| Placebo Arm | 13 |
Time from admitting to ICU to discharge. (NCT03422159)
Timeframe: From admission to the ICU until final discharge from the ICU, up to an average of 7 days.
| Intervention | days (Mean) |
|---|---|
| Treatment Arm | 4.76 |
| Placebo Arm | 4.66 |
ICU mortality rate (NCT03422159)
Timeframe: From admission to hospital until final discharge from the ICU, up to 28 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment Arm | 6 |
| Placebo Arm | 10 |
PCT at 96 hours minus initial PCT, divided by the initial PCT multiplied by 100. (NCT03422159)
Timeframe: 4 days post-randomization
| Intervention | Percent (Mean) |
|---|---|
| Treatment Arm | 63 |
| Placebo Arm | 58 |
Defined as the time from starting the active treatment/placebo to discontinuation of all pressors. (NCT03422159)
Timeframe: From start of vasopressor medication to final discontinuation of vasopressor medication, up to 7 days.
| Intervention | hours (Mean) |
|---|---|
| HAT Treatment | 27 |
| Comparator | 53 |
Number of days alive and off of the ventilator at day 28. (NCT03422159)
Timeframe: 28 Days post-randomization
| Intervention | Days (Mean) |
|---|---|
| Treatment Arm | 22 |
| Placebo Arm | 22.4 |
3 reviews available for thiamine and Electrolytes
| Article | Year |
|---|---|
[Refeeding syndrome : Pathophysiology, risk factors, prevention, and treatment].
Topics: Blood Glucose; Electrolytes; Energy Metabolism; Fasting; Humans; Hunger; Insulin; Magnesium; Malnutr | 2018 |
Unpeeling the Evidence for the Banana Bag: Evidence-Based Recommendations for the Management of Alcohol-Associated Vitamin and Electrolyte Deficiencies in the ICU.
Topics: Alcohol-Induced Disorders; Dietary Supplements; Electrolytes; Folic Acid; Humans; Intensive Care Uni | 2016 |
Unpeeling the Evidence for the Banana Bag: Evidence-Based Recommendations for the Management of Alcohol-Associated Vitamin and Electrolyte Deficiencies in the ICU.
Topics: Alcohol-Induced Disorders; Dietary Supplements; Electrolytes; Folic Acid; Humans; Intensive Care Uni | 2016 |
Unpeeling the Evidence for the Banana Bag: Evidence-Based Recommendations for the Management of Alcohol-Associated Vitamin and Electrolyte Deficiencies in the ICU.
Topics: Alcohol-Induced Disorders; Dietary Supplements; Electrolytes; Folic Acid; Humans; Intensive Care Uni | 2016 |
Unpeeling the Evidence for the Banana Bag: Evidence-Based Recommendations for the Management of Alcohol-Associated Vitamin and Electrolyte Deficiencies in the ICU.
Topics: Alcohol-Induced Disorders; Dietary Supplements; Electrolytes; Folic Acid; Humans; Intensive Care Uni | 2016 |
[Late withdrawal syndrome].
Topics: Alcohol Withdrawal Delirium; Benzodiazepines; Diagnosis, Differential; Electrolytes; Ethanol; Fluid | 2003 |
2 trials available for thiamine and Electrolytes
| Article | Year |
|---|---|
Management of acute metabolic decompensation in maple syrup urine disease: a multi-center study.
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Electrolytes; Female; Glucose; Health Care Surve | 1999 |
[Possible clinical cure in a high percentage of cases of liver cirrhosis with a treatment based on high doses of testosterone and vitamin B 1 ].
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Bilirubin; Blood Proteins; Blood Sedimentation; Child | 1973 |
22 other studies available for thiamine and Electrolytes
| Article | Year |
|---|---|
Recognizing neonatal refeeding syndrome and thiamin supplementation: A case report.
Topics: Adult; Child; Dietary Supplements; Electrolytes; Humans; Infant, Newborn; Refeeding Syndrome; Thiami | 2023 |
Influence of Glucose Dosage in Parenteral Nutrition on Body Thiamine Levels in Rats.
Topics: Amino Acids; Animals; Brain; Electrolytes; Glucose; Japan; Liver; Male; Muscle, Skeletal; Organ Spec | 2019 |
Refeeding syndrome is uncommon in alcoholics admitted to a hospital detoxification unit.
Topics: Adult; Aged; Alcoholism; Blood Chemical Analysis; Diagnostic Tests, Routine; Diet; Electrolytes; Fem | 2014 |
Stability of hydrophilic vitamins mixtures in the presence of electrolytes and trace elements for parenteral nutrition: a nuclear magnetic resonance spectroscopy investigation.
Topics: Drug Stability; Electrolytes; Flavin Mononucleotide; Hydrophobic and Hydrophilic Interactions; Magne | 2015 |
Application of renewable silver amalgam annular band electrode to voltammetric determination of vitamins C, B1 and B2.
Topics: Alloys; Ascorbic Acid; Beverages; Buffers; Calibration; Electrochemistry; Electrodes; Electrolytes; | 2011 |
[Acute experimental triorthocresylphosphate poisoning. II. Behavior of the electrolytes and vitamin B-1].
Topics: Electrolytes; Organophosphate Poisoning; Phosphorus; Poisons; Thiamine; Vitamins | 1962 |
Electrolyte changes in tissues of chronic thiamine deficient rats and influence of certain steroids.
Topics: Animals; Electrolytes; Rats; Steroids; Thiamine; Thiamine Deficiency; Vitamin B Deficiency | 1952 |
Lead poisoning and toxicokinetics in a heifer and fetus treated with CaNa2 EDTA and thiamine.
Topics: Animals; Antidotes; Brain; Calcium; Cattle; Cattle Diseases; Copper; Edetic Acid; Electrolytes; Fece | 1995 |
Stability of cocarboxylase in parenteral nutrition mixtures stored in multilayer bags.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Drug Stability; Electrolytes; Glucose; Humans; Pa | 1998 |
Primary alcoholic heart disease.
Topics: Alcoholism; Cardiomegaly; Cell Membrane Permeability; Diagnosis, Differential; Diet Therapy; Digital | 1975 |
[Studies on the state of vitamins B1, B2 and B6 in Down's syndrome].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Child; Down Syndrome; Electrolytes; Female; Human | 1975 |
[Rapid replacement of fluid loss during work at high temperatures].
Topics: Ascorbic Acid; Drinking; Electrolytes; Humans; Physical Exertion; Sweating; Temperature; Thiamine; W | 1978 |
Sulfur-induced polioencephalomalacia in sheep: some biochemical changes.
Topics: Animals; Aspartate Aminotransferases; Creatine Kinase; Electrolytes; Encephalomalacia; gamma-Glutamy | 1989 |
[EKG changes in acute pachycarpine poisoning].
Topics: Acute Disease; Adenosine Triphosphate; Adult; Alkaloids; Electrocardiography; Electrolytes; Erythroc | 1973 |
Kinetic salt effect in pharmaceutical investigations.
Topics: Chemical Phenomena; Chemistry; Chlorpromazine; Echothiophate Iodide; Electrolytes; Ions; Kinetics; M | 1970 |
[Electron-microscopic detection of intracellular electrolytes and its physiological significance (4)].
Topics: Animals; Autoradiography; Birds; Chlorine; Electrolytes; Gastric Mucosa; Histocytochemistry; Intesti | 1969 |
Biochemical aspects of an outbreak of bovine polioencephalomalacia.
Topics: Animals; Cattle; Cattle Diseases; Electrolytes; Encephalomalacia; Lactates; Pyruvates; Rumen; Thiami | 1970 |
Thiamine deficiency in an Atlantic bottle-nosed dolphin (Tursiops truncatus) on a diet of raw fish.
Topics: Alkaline Phosphatase; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aspartate Am | 1970 |
Optimal therapy of the alcohol withdrawal state.
Topics: Adult; Chlordiazepoxide; Chlorpromazine; Electrolytes; Female; Humans; Hydroxyzine; Male; Paraldehyd | 1970 |
[Pathology caused by tri-orthocresylphosphate. Experimental research].
Topics: Animals; Brain Diseases; Cholinesterases; Cresols; Electroencephalography; Electrolytes; Electromyog | 1968 |
[Clinical study of some metabolic parameters after administration of thiamine in high doses].
Topics: Acid Phosphatase; Acid-Base Equilibrium; Adult; Alkaline Phosphatase; Carbohydrate Metabolism; Elect | 1968 |
[On some plasma electrolytes during NLA II associated with thiaminic synaptolysis].
Topics: Adult; Aged; Calcium; Chlorine; Electrolytes; Humans; Middle Aged; Neuroleptanalgesia; Potassium; So | 1968 |