thiamine has been researched along with Diabetic Angiopathies in 17 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
Diabetic Angiopathies: VASCULAR DISEASES that are associated with DIABETES MELLITUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thiamine is an essential cofactor in carbohydrate metabolism and individuals with diabetes are thiamine deficient." | 6.47 | Thiamine deficiency in diabetes mellitus and the impact of thiamine replacement on glucose metabolism and vascular disease. ( Cummings, MH; Laight, D; Page, GL, 2011) |
| " However, slower absorption and reduced bioavailability is a major limiting factor for its clinical use." | 2.58 | Therapeutic potential of benfotiamine and its molecular targets. ( Belur, PD; Howarth, FC; Ojha, S; Raj, V; Subramanya, SB, 2018) |
| "Thiamine is an essential cofactor in carbohydrate metabolism and individuals with diabetes are thiamine deficient." | 2.47 | Thiamine deficiency in diabetes mellitus and the impact of thiamine replacement on glucose metabolism and vascular disease. ( Cummings, MH; Laight, D; Page, GL, 2011) |
| "Thiamine is a coenzyme important in intracellular glucose metabolism." | 1.31 | Thiamine (Vitamin B1) protects against glucose- and insulin-mediated proliferation of human infragenicular arterial smooth muscle cells. ( Arora, S; Avena, R; Carmody, BJ; Cosby, K; Sidawy, AN, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 11 (64.71) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raj, V | 1 |
| Ojha, S | 1 |
| Howarth, FC | 1 |
| Belur, PD | 1 |
| Subramanya, SB | 1 |
| Wong, CY | 1 |
| Qiuwaxi, J | 1 |
| Chen, H | 1 |
| Li, SW | 1 |
| Chan, HT | 1 |
| Tam, S | 1 |
| Shu, XO | 1 |
| Lau, CP | 1 |
| Kwong, YL | 1 |
| Tse, HF | 1 |
| Page, GL | 1 |
| Laight, D | 1 |
| Cummings, MH | 1 |
| Engelen, L | 1 |
| Stehouwer, CD | 1 |
| Schalkwijk, CG | 1 |
| Obrenovich, ME | 1 |
| Monnier, VM | 1 |
| Stepuro, II | 1 |
| Suzuki, S | 1 |
| Yamagishi, S | 1 |
| Imaizumi, T | 1 |
| Thomas, MC | 1 |
| Baynes, JW | 1 |
| Thorpe, SR | 1 |
| Cooper, ME | 1 |
| Gadau, S | 1 |
| Emanueli, C | 1 |
| Van Linthout, S | 1 |
| Graiani, G | 1 |
| Todaro, M | 1 |
| Meloni, M | 1 |
| Campesi, I | 1 |
| Invernici, G | 1 |
| Spillmann, F | 1 |
| Ward, K | 1 |
| Madeddu, P | 1 |
| Małecka, SA | 1 |
| Poprawski, K | 1 |
| Bilski, B | 1 |
| Thornalley, PJ | 1 |
| Babaei-Jadidi, R | 1 |
| Al Ali, H | 1 |
| Rabbani, N | 1 |
| Antonysunil, A | 1 |
| Larkin, J | 1 |
| Ahmed, A | 1 |
| Rayman, G | 1 |
| Bodmer, CW | 1 |
| Avena, R | 1 |
| Arora, S | 1 |
| Carmody, BJ | 1 |
| Cosby, K | 1 |
| Sidawy, AN | 1 |
| Ishii, N | 1 |
| Shirai, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-Blind Clinical Trial of Benfotiamine Treatment in Diabetic Nephropathy[NCT00565318] | Phase 4 | 86 participants (Anticipated) | Interventional | 2007-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for thiamine and Diabetic Angiopathies
| Article | Year |
|---|---|
Therapeutic potential of benfotiamine and its molecular targets.
Topics: Animals; Diabetic Angiopathies; Humans; Signal Transduction; Thiamine | 2018 |
Thiamine deficiency in diabetes mellitus and the impact of thiamine replacement on glucose metabolism and vascular disease.
Topics: Animals; Blood Glucose; Diabetic Angiopathies; Dietary Supplements; Endothelium, Vascular; Humans; H | 2011 |
Current therapeutic interventions in the glycation pathway: evidence from clinical studies.
Topics: Animals; Atherosclerosis; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathie | 2013 |
[Role of mitochondrial dysfunction in pathogenesis of diabetic microangiopathy].
Topics: Antioxidants; Coenzymes; Diabetic Angiopathies; DNA Damage; DNA, Mitochondrial; Drug Design; Electro | 2005 |
[Progress on the drug therapy for diabetic microangiopathies: AGE inhibitors].
Topics: Animals; Clinical Trials as Topic; Depression, Chemical; Diabetic Angiopathies; Glycation End Produc | 2005 |
The role of AGEs and AGE inhibitors in diabetic cardiovascular disease.
Topics: Animals; Diabetic Angiopathies; Glycation End Products, Advanced; Guanidines; Humans; Ligands; Oxida | 2005 |
[Prophylactic and therapeutic application of thiamine (vitamin B1)--a new point of view].
Topics: Animals; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus; Diabetic Angiopathies; Humans; Pai | 2006 |
10 other studies available for thiamine and Diabetic Angiopathies
| Article | Year |
|---|---|
Daily intake of thiamine correlates with the circulating level of endothelial progenitor cells and the endothelial function in patients with type II diabetes.
Topics: Brachial Artery; Cell Count; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelial Cells; En | 2008 |
[Diabetic neuropathies and angiopathies. Compensating for thiamine deficiency].
Topics: Adjuvants, Immunologic; Diabetic Angiopathies; Diabetic Neuropathies; Humans; Thiamine; Thiamine Def | 2010 |
[Prevention of complications in diabetes mellitus. Interdisciplinary collaboration to control sequelae].
Topics: Adjuvants, Immunologic; Animals; Cooperative Behavior; Cross-Sectional Studies; Diabetes Complicatio | 2011 |
Vitamin B1 blocks damage caused by hyperglycemia.
Topics: Aging; Animals; Cattle; Diabetic Angiopathies; Glucose Intolerance; Glycation End Products, Advanced | 2003 |
Thiamine and vasculopathies.
Topics: Diabetic Angiopathies; Humans; Hydrogen-Ion Concentration; Models, Biological; Oxidation-Reduction; | 2005 |
Benfotiamine accelerates the healing of ischaemic diabetic limbs in mice through protein kinase B/Akt-mediated potentiation of angiogenesis and inhibition of apoptosis.
Topics: Animals; Apoptosis; Blotting, Western; Body Weight; Caspase 3; Caspase Inhibitors; Caspases; Cell Pr | 2006 |
Benfotiamine. Monograph.
Topics: Alcoholic Neuropathy; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Humans; | 2006 |
High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease.
Topics: Albuminuria; Biomarkers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies | 2007 |
Thiamine (Vitamin B1) protects against glucose- and insulin-mediated proliferation of human infragenicular arterial smooth muscle cells.
Topics: Aged; Arteriosclerosis; Cell Division; Cells, Cultured; Diabetic Angiopathies; DNA; Glucose; Humans; | 2000 |
[Diabetic impotence].
Topics: Alprostadil; Diabetes Complications; Diabetic Angiopathies; Diabetic Neuropathies; Diagnosis, Differ | 1991 |