Page last updated: 2024-10-20

thiamine and Dementia

thiamine has been researched along with Dementia in 14 studies

thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.

Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.

Research Excerpts

ExcerptRelevanceReference
" Furthermore, we suggest thiamine, which is frequently depleted in AUD, to be a key modulator in this process: Thiamine deficiency impairs the integrity of the blood-brain barrier, thereby enabling iron to pass through and accumulate in the brain."9.05Does thiamine protect the brain from iron overload and alcohol-related dementia? ( Hametner, S; König, D; Listabarth, S; Vyssoki, B, 2020)
"The earliest and perhaps best example of an interaction between nutrition and dementia is related to thiamine (vitamin B1)."8.93Vitamin B1 (thiamine) and dementia. ( Cirio, RT; Elder, J; Fonzetti, P; Gibson, GE; Hirsch, JA; Jordan, BD, 2016)
"The results indicated that thiamine therapy could be a protective factor for dementia development in patients with alcohol use disorder."7.91Thiamine for preventing dementia development among patients with alcohol use disorder: A nationwide population-based cohort study. ( Chang, YH; Chen, YY; Chou, WP; Ko, CH; Lin, HC, 2019)
" Furthermore, we suggest thiamine, which is frequently depleted in AUD, to be a key modulator in this process: Thiamine deficiency impairs the integrity of the blood-brain barrier, thereby enabling iron to pass through and accumulate in the brain."5.05Does thiamine protect the brain from iron overload and alcohol-related dementia? ( Hametner, S; König, D; Listabarth, S; Vyssoki, B, 2020)
"The earliest and perhaps best example of an interaction between nutrition and dementia is related to thiamine (vitamin B1)."4.93Vitamin B1 (thiamine) and dementia. ( Cirio, RT; Elder, J; Fonzetti, P; Gibson, GE; Hirsch, JA; Jordan, BD, 2016)
"An elevated homocysteine level is a known strong risk factor for vascular dementia (VaD) and Alzheimer's disease (AD)."4.02Association Between Homocysteine and Vitamin Levels in Demented Patients. ( Borucki, K; Busse, M; Busse, S; Frodl, T; Hoffmann, J; von Hoff, F, 2021)
"The results indicated that thiamine therapy could be a protective factor for dementia development in patients with alcohol use disorder."3.91Thiamine for preventing dementia development among patients with alcohol use disorder: A nationwide population-based cohort study. ( Chang, YH; Chen, YY; Chou, WP; Ko, CH; Lin, HC, 2019)
"Despite the absence of thiamine deficiency, whole blood thiamine was lower in patients with dementia and delirium compared to those without."3.91Blood Thiamine Level and Cognitive Function in Older Hospitalized Patients. ( Angersbach, B; Klimek, CN; Lueg, G; Pourhassan, M; Wirth, R, 2019)
" We report a patient with Wernicke encephalopathy, a B1 deficiency and pellagra, a niacin deficiency."3.81Wernicke encephalopathy and pellagra in an alcoholic and malnourished patient. ( Kinoshita, K; Taguchi, S; Terada, N; Tokuda, Y, 2015)
"The thiamine status was measured by determining the thiamine pyrophosphate stimulating effect of transketolase enzyme activity in whole blood."1.26Blood values of some vitamins in long-stay psycho-geriatric patients. ( Basu, TK; Jenner, M; Jordan, SJ; Williams, DC, 1976)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's7 (50.00)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Listabarth, S1
König, D1
Vyssoki, B1
Hametner, S1
Frank, J1
Kisters, K1
Stirban, OA1
Obeid, R1
Lorkowski, S1
Wallert, M1
Egert, S1
Podszun, MC1
Eckert, GP1
Pettersen, JA1
Venturelli, S1
Classen, HG1
Golombek, J1
Hoffmann, J1
Busse, S1
von Hoff, F1
Borucki, K1
Frodl, T1
Busse, M1
Chou, WP1
Chang, YH2
Lin, HC1
Chen, YY1
Ko, CH1
Pourhassan, M1
Angersbach, B1
Lueg, G1
Klimek, CN1
Wirth, R1
Yanagawa, Y1
Mikasa, M1
Nishioka, K1
Hirano, K1
Terada, N1
Kinoshita, K1
Taguchi, S1
Tokuda, Y1
Kuller, LH1
Gibson, GE1
Hirsch, JA1
Fonzetti, P1
Jordan, BD1
Cirio, RT1
Elder, J1
Hoffman, R1
Frick, B1
Gruber, B1
Schroecksnadel, K1
Leblhuber, F1
Fuchs, D1
Leevy, CM1
Basu, TK1
Jordan, SJ1
Jenner, M1
Williams, DC1
Kershaw, PW1

Reviews

4 reviews available for thiamine and Dementia

ArticleYear
Does thiamine protect the brain from iron overload and alcohol-related dementia?
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2020, Volume: 16, Issue:11

    Topics: Alcoholism; Animals; Brain; Dementia; Humans; Iron Overload; Thiamine; Thiamine Deficiency

2020
The role of biofactors in the prevention and treatment of age-related diseases.
    BioFactors (Oxford, England), 2021, Volume: 47, Issue:4

    Topics: Aged; Cardiovascular Diseases; Dementia; Diabetes Mellitus; Dietary Fiber; Dietary Supplements; Epig

2021
Vitamin B1 (thiamine) and dementia.
    Annals of the New York Academy of Sciences, 2016, Volume: 1367, Issue:1

    Topics: Alzheimer Disease; Animals; Dementia; Glucose; Humans; Randomized Controlled Trials as Topic; Thiami

2016
Thiamin deficiency and alcoholism.
    Annals of the New York Academy of Sciences, 1982, Volume: 378

    Topics: Alcoholism; Dementia; Diet; Digestive System; Heart Diseases; Humans; Intestinal Absorption; Phospho

1982

Trials

1 trial available for thiamine and Dementia

ArticleYear
Homocysteine but not neopterin declines in demented patients on B vitamins.
    Journal of neural transmission (Vienna, Austria : 1996), 2006, Volume: 113, Issue:11

    Topics: Dementia; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Neopterin; Thiamine;

2006

Other Studies

9 other studies available for thiamine and Dementia

ArticleYear
Association Between Homocysteine and Vitamin Levels in Demented Patients.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 81, Issue:4

    Topics: Aged; Aged, 80 and over; Dementia; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Thia

2021
Thiamine for preventing dementia development among patients with alcohol use disorder: A nationwide population-based cohort study.
    Clinical nutrition (Edinburgh, Scotland), 2019, Volume: 38, Issue:3

    Topics: Adult; Aged; Alcoholism; Comorbidity; Dementia; Female; Humans; Male; Middle Aged; Protective Agents

2019
Blood Thiamine Level and Cognitive Function in Older Hospitalized Patients.
    Journal of geriatric psychiatry and neurology, 2019, Volume: 32, Issue:2

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Cognition; Cognitive Dysfunction; Cross-Section

2019
Dementia complicated with Takotsubo cardiomyopathy associated with unconsciousness induced by Wernicke's encephalopathy.
    BMJ case reports, 2013, May-09, Volume: 2013

    Topics: Aged, 80 and over; Dementia; Diet; Female; Humans; Social Isolation; Stress, Psychological; Takotsub

2013
Wernicke encephalopathy and pellagra in an alcoholic and malnourished patient.
    BMJ case reports, 2015, Oct-21, Volume: 2015

    Topics: Alcoholism; Confusion; Dementia; Dermatitis; Diarrhea; Humans; Magnetic Resonance Imaging; Male; Mid

2015
Thiamine Metabolites and Dementia?
    EBioMedicine, 2016, Volume: 3

    Topics: Dementia; Humans; Thiamine; Thiamine Deficiency; Thiamine Pyrophosphate

2016
Thiamine deficiency in the Western diet and dementia risk.
    The British journal of nutrition, 2016, Volume: 116, Issue:1

    Topics: Dementia; Diet; Diet, Western; Humans; Thiamine; Thiamine Deficiency

2016
Blood values of some vitamins in long-stay psycho-geriatric patients.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1976, Volume: 46, Issue:1

    Topics: Age Factors; Aged; Ascorbic Acid; Dementia; Female; Humans; Intracranial Arteriosclerosis; Length of

1976
Blood thiamine and nicotinic acid levels in alcoholism and confusional states.
    The British journal of psychiatry : the journal of mental science, 1967, Volume: 113, Issue:497

    Topics: Adult; Aged; Alcoholism; Dementia; Humans; Intracranial Arteriosclerosis; Middle Aged; Neurologic Ma

1967