thiamine has been researched along with Degenerative Diseases, Central Nervous System in 11 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Emerging evidence suggests that thiamine deficiency (TD), the cause of Wernicke's encephalopathy, produces alterations in brain function and structural damage that closely model a number of maladies in which neurodegeneration is a characteristic feature, including Alzheimer's disease, amyotrophic lateral sclerosis, Parkinson's disease, multiple sclerosis, along with alcoholic brain disease, stroke, and traumatic brain injury." | 8.87 | Modeling neurodegenerative disease pathophysiology in thiamine deficiency: consequences of impaired oxidative metabolism. ( Hazell, AS; Jhala, SS, 2011) |
| "Thiamine or vitamin B1, an essential micronutrient mainly involved in energy production, has a beneficial impact on the nervous system, and its deficiency can be associated with the development and progression of neurodegenerative diseases." | 8.02 | Thiamine-producing lactic acid bacteria and their potential use in the prevention of neurodegenerative diseases. ( de Moreno de LeBlanc, A; LeBlanc, JG; Savoy de Giori, G; Teran, MDM, 2021) |
| "Neurodegenerative diseases are characterized by abnormalities in oxidative processes, region-selective neuron loss, and diminished thiamine-dependent enzymes." | 7.72 | Reversal of thiamine deficiency-induced neurodegeneration. ( DeGiorgio, LA; Gibson, GE; Ke, ZJ; Volpe, BT, 2003) |
| "Thiamine is a water-soluble vitamin." | 6.52 | [The role of thiamine in neurodegenerative diseases]. ( Anuszewska, EL; Bubko, I; Gruber, BM, 2015) |
| "Emerging evidence suggests that thiamine deficiency (TD), the cause of Wernicke's encephalopathy, produces alterations in brain function and structural damage that closely model a number of maladies in which neurodegeneration is a characteristic feature, including Alzheimer's disease, amyotrophic lateral sclerosis, Parkinson's disease, multiple sclerosis, along with alcoholic brain disease, stroke, and traumatic brain injury." | 4.87 | Modeling neurodegenerative disease pathophysiology in thiamine deficiency: consequences of impaired oxidative metabolism. ( Hazell, AS; Jhala, SS, 2011) |
| "Thiamine or vitamin B1, an essential micronutrient mainly involved in energy production, has a beneficial impact on the nervous system, and its deficiency can be associated with the development and progression of neurodegenerative diseases." | 4.02 | Thiamine-producing lactic acid bacteria and their potential use in the prevention of neurodegenerative diseases. ( de Moreno de LeBlanc, A; LeBlanc, JG; Savoy de Giori, G; Teran, MDM, 2021) |
| "Abnormalities in oxidative metabolism and reductions of thiamine-dependent enzymes accompany many age-related neurodegenerative diseases." | 3.74 | Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism. ( Gibson, GE; Karuppagounder, SS; Shi, Q; Xu, H, 2007) |
| "Neurodegenerative diseases are characterized by abnormalities in oxidative processes, region-selective neuron loss, and diminished thiamine-dependent enzymes." | 3.72 | Reversal of thiamine deficiency-induced neurodegeneration. ( DeGiorgio, LA; Gibson, GE; Ke, ZJ; Volpe, BT, 2003) |
| "Thiamine is a water-soluble vitamin." | 2.52 | [The role of thiamine in neurodegenerative diseases]. ( Anuszewska, EL; Bubko, I; Gruber, BM, 2015) |
| "Treatment with thiamine while awaiting the outcome of diagnostic tests may be a good choice." | 1.72 | Case report of two affected siblings in a family with thiamine metabolism dysfunction syndrome 5: a rare, but treatable neurodegenerative disease. ( Chen, H; Chen, Y; Huang, Z; Li, X; Sun, X; Xie, J; Yi, Z; Yu, X; Zhong, J, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 5 (45.45) | 2.80 |
| Authors | Studies |
|---|---|
| Ramamoorthy, K | 1 |
| Yoshimura, R | 1 |
| Al-Juburi, S | 1 |
| Anandam, KY | 1 |
| Kapadia, R | 1 |
| Alachkar, A | 1 |
| Abbott, GW | 1 |
| Said, HM | 1 |
| Li, X | 1 |
| Huang, Z | 1 |
| Chen, Y | 1 |
| Sun, X | 1 |
| Yi, Z | 1 |
| Xie, J | 1 |
| Yu, X | 1 |
| Chen, H | 1 |
| Zhong, J | 1 |
| Bettendorff, L | 1 |
| Rüsch, CT | 1 |
| Wortmann, SB | 1 |
| Kovacs-Nagy, R | 1 |
| Grehten, P | 1 |
| Häberle, J | 1 |
| Latal, B | 1 |
| Stettner, GM | 1 |
| Teran, MDM | 1 |
| de Moreno de LeBlanc, A | 1 |
| Savoy de Giori, G | 1 |
| LeBlanc, JG | 1 |
| Bubko, I | 1 |
| Gruber, BM | 1 |
| Anuszewska, EL | 1 |
| Jhala, SS | 1 |
| Hazell, AS | 1 |
| Ke, ZJ | 1 |
| DeGiorgio, LA | 1 |
| Volpe, BT | 1 |
| Gibson, GE | 2 |
| Kukulska-Pawluczuk, B | 1 |
| Princ, R | 1 |
| Burzyńska-Makuch, M | 1 |
| Borkowska, A | 1 |
| Karuppagounder, SS | 1 |
| Shi, Q | 1 |
| Xu, H | 1 |
| Balk, E | 1 |
| Chung, M | 1 |
| Raman, G | 1 |
| Tatsioni, A | 1 |
| Chew, P | 1 |
| Ip, S | 1 |
| DeVine, D | 1 |
| Lau, J | 1 |
4 reviews available for thiamine and Degenerative Diseases, Central Nervous System
| Article | Year |
|---|---|
Synthetic Thioesters of Thiamine: Promising Tools for Slowing Progression of Neurodegenerative Diseases.
Topics: Animals; Coenzymes; Humans; Neurodegenerative Diseases; Thiamine; Thiamine Pyrophosphate | 2023 |
[The role of thiamine in neurodegenerative diseases].
Topics: Adult; Aged; Aged, 80 and over; Brain; Female; Humans; Male; Middle Aged; Neurodegenerative Diseases | 2015 |
Modeling neurodegenerative disease pathophysiology in thiamine deficiency: consequences of impaired oxidative metabolism.
Topics: Animals; Energy Metabolism; Humans; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Phosp | 2011 |
B vitamins and berries and age-related neurodegenerative disorders.
Topics: Aging; Alzheimer Disease; Animals; Blueberry Plants; Cognition; Disease Models, Animal; Folic Acid; | 2006 |
7 other studies available for thiamine and Degenerative Diseases, Central Nervous System
| Article | Year |
|---|---|
Alzheimer's disease is associated with disruption in thiamin transport physiology: A potential role for neuroinflammation.
Topics: Acinar Cells; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cytokines; Humans; Membrane Transpo | 2022 |
Case report of two affected siblings in a family with thiamine metabolism dysfunction syndrome 5: a rare, but treatable neurodegenerative disease.
Topics: Ataxia; Brain Diseases; Humans; Male; Muscle Hypotonia; Mutation; Neurodegenerative Diseases; Siblin | 2022 |
Thiamine Pyrophosphokinase Deficiency due to Mutations in the TPK1 Gene: A Rare, Treatable Neurodegenerative Disorder.
Topics: Child; Dietary Supplements; Humans; Magnesium; Neurodegenerative Diseases; Rare Diseases; Thiamin Py | 2021 |
Thiamine-producing lactic acid bacteria and their potential use in the prevention of neurodegenerative diseases.
Topics: Amprolium; Cell Death; Humans; Lactobacillales; Neurodegenerative Diseases; Thiamine | 2021 |
Reversal of thiamine deficiency-induced neurodegeneration.
Topics: Animals; Brain; Cell Death; Disease Models, Animal; Fluoresceins; Fluorescent Dyes; Heme Oxygenase ( | 2003 |
[Marchiafava-Bignami disease].
Topics: Adult; Alcohol-Induced Disorders, Nervous System; Alcoholism; Brain Diseases; Corpus Callosum; Demye | 2006 |
Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism.
Topics: Animals; Biomarkers; Brain; Cell Death; Cell Survival; Cytokines; Down-Regulation; Encephalitis; Imm | 2007 |