thiamine has been researched along with Cleft Palate, Isolated in 13 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 24 A/WySn female mice were orally supplemented with high doses (80 mg/kg) of thiamine at different times of pregnancy (5 groups, n = 90)." | 3.85 | Oral vitamin B1-substitution does not decrease genetically determined cleft rate in mice (A/WySn). ( Bialek, J; Kalmring, F; Scheller, C; Scheller, K; Schubert, J, 2017) |
| "Because several previous authors have repeatedly described treatment with thiamine as one of the sufficient prophylactic measures in slowing the development of viscerocranial malformations, especially cleft alveolus and palate, it is of utmost importance that the timing of treatment and dosage of thiamine be taken into consideration not only in animal experiments but also when applying results to humans." | 1.30 | Application of thiamine in preventing malformations, specifically cleft alveolus and palate, during the intrauterine development of rats. ( Bienengräber, V; Fanghänel, J; Kundt, G; Malek, FA, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scheller, K | 4 |
| Kalmring, F | 2 |
| Scheller, C | 2 |
| Schubert, J | 6 |
| Bialek, J | 1 |
| Quitzke, V | 1 |
| Kappler, M | 1 |
| Röckl, T | 1 |
| Syska, E | 1 |
| Schmidt, R | 1 |
| Krapels, IP | 1 |
| van Rooij, IA | 1 |
| Ocké, MC | 1 |
| van Cleef, BA | 1 |
| Kuijpers-Jagtman, AM | 1 |
| Steegers-Theunissen, RP | 1 |
| Bienengräber, V | 2 |
| Fanghänel, J | 2 |
| Malek, FA | 1 |
| Kundt, G | 2 |
| Malek, F | 1 |
| Briggs, RM | 1 |
| Dostal, M | 1 |
| Neumann, HJ | 1 |
| Zenk, W | 1 |
| Wagner, T | 1 |
| Möckel, M | 1 |
13 other studies available for thiamine and Cleft Palate, Isolated
| Article | Year |
|---|---|
Oral vitamin B1-substitution does not decrease genetically determined cleft rate in mice (A/WySn).
Topics: Administration, Oral; Animals; Cleft Lip; Cleft Palate; Dietary Supplements; Female; Mice; Pregnancy | 2017 |
New molecular aspects in the mechanism of oromaxillofacial cleft prevention by B-vitamins.
Topics: Animals; Biological Transport; Cleft Lip; Cleft Palate; Disease Models, Animal; Electrophoresis, Aga | 2018 |
Lower concentrations of B-vitamin subgroups in the serum and amniotic fluid correlate to cleft lip and palate appearance in the offspring of A/WySn mice.
Topics: Adenine; Alkaline Phosphatase; Amniotic Fluid; Animals; Chromatography, High Pressure Liquid; Cleft | 2013 |
Sex distribution is a factor in teratogenically induced clefts and in the anti-teratogenic effect of thiamine in mice, but not in genetically determined cleft appearance.
Topics: Animals; Cleft Lip; Cleft Palate; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Inbred S | 2016 |
The time of palatal fusion in mice: a factor of strain susceptibility to teratogens.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Genetic Predisposition to Disease; Gestational A | 2004 |
Maternal dietary B vitamin intake, other than folate, and the association with orofacial cleft in the offspring.
Topics: Adult; Case-Control Studies; Cleft Lip; Cleft Palate; Diet; Energy Intake; Female; Folic Acid; Human | 2004 |
Application of thiamine in preventing malformations, specifically cleft alveolus and palate, during the intrauterine development of rats.
Topics: Abnormalities, Drug-Induced; Alveolar Process; Animals; Body Weight; Bone and Bones; Cleft Palate; C | 1997 |
Disturbances of palatogenesis and their prophylaxis in animal experiments.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Embryonic and Fetal Development; Female; Humans; | 1999 |
Vitamin supplementation as a possible factor in the incidence of cleft lip/palate deformities in humans.
Topics: Ascorbic Acid; Calcium; Cleft Lip; Cleft Palate; Female; Folic Acid; Humans; Infant, Newborn; Matern | 1976 |
Further studies on protective effects of vitamins in cyclophosphamide-induced cleft palate.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cleft Palate; Cyclophosphamide; Female; Fetus; Li | 1990 |
[Studies and results of the etiology and prevention of lip-jaw-palate clefts].
Topics: Cleft Lip; Cleft Palate; Combined Modality Therapy; Female; Genetic Markers; Humans; Infant; Infant, | 1989 |
[Value of different drugs in the prevention of abnormalities].
Topics: Actihaemyl; Animals; Cleft Palate; Dexamethasone; Mice; Pyridoxine; Thiamine; Vitamin B Complex | 1986 |
[Teratogen-modified palatogenesis in the Uje: WIST rat. 2. The effect of thiamine on the incidence of cheilognathopalatoschisis].
Topics: Animals; Cleft Lip; Cleft Palate; Disease Models, Animal; Female; Glycine; Maxilla; Palate; Pregnanc | 1987 |