thiamine has been researched along with Chemical and Drug Induced Liver Injury in 17 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The major adverse effect associated with systemic administration of Fluconazole (FLZ), is hepatic toxicity." | 1.51 | Vitamin B combination reduces fluconazole toxicity in Wistar rats. ( Al-Abbasi, FA; Anwar, F; Mushtaq, G; Sadath, S, 2019) |
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (47.06) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Greene, N | 1 |
| Fisk, L | 1 |
| Naven, RT | 1 |
| Note, RR | 1 |
| Patel, ML | 1 |
| Pelletier, DJ | 1 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Liu, Z | 1 |
| Shi, Q | 2 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Al-Abbasi, FA | 1 |
| Sadath, S | 1 |
| Mushtaq, G | 1 |
| Anwar, F | 1 |
| Turan, MI | 1 |
| Siltelioglu Turan, I | 1 |
| Mammadov, R | 1 |
| Altınkaynak, K | 1 |
| Kisaoglu, A | 1 |
| Zahr, NM | 1 |
| Luong, R | 1 |
| Sullivan, EV | 1 |
| Pfefferbaum, A | 1 |
| TERZANI, A | 1 |
| FRANK, O | 2 |
| BAKER, H | 2 |
| LEEVY, CM | 2 |
| Wang, C | 1 |
| Liang, J | 1 |
| Zhang, C | 1 |
| Bi, Y | 1 |
| Shi, X | 1 |
| Yamano, S | 1 |
| Yoshimura, H | 1 |
| Shimizu, M | 1 |
| Prokopenko, LG | 1 |
| Konoplia, AI | 1 |
| Yamamoto, H | 1 |
| Luisada-Opper, AV | 1 |
| Feingold, S | 1 |
| Braginskaia, LL | 1 |
| Geller, LI | 1 |
| Klopotovskiĭ, EP | 1 |
1 review available for thiamine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
16 other studies available for thiamine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Vitamin B combination reduces fluconazole toxicity in Wistar rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; | 2019 |
The effect of thiamine and thiamine pyrophosphate on oxidative liver damage induced in rats with cisplatin.
Topics: Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cisplati | 2013 |
Measurement of serum, liver, and brain cytokine induction, thiamine levels, and hepatopathology in rats exposed to a 4-day alcohol binge protocol.
Topics: Alcoholism; Alkaline Phosphatase; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Chemical | 2010 |
[DAMAGE FROM THERAPY].
Topics: Adrenal Cortex Hormones; Anemia; Anemia, Aplastic; Anticoagulants; Antipyrine; Blood Group Incompati | 1963 |
VITAMIN-BINDING CAPACITY OF EXPERIMENTALLY INJURED LIVER.
Topics: Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Folic Acid; Hepatitis; Leuco | 1964 |
Effect of ascorbic Acid and thiamine supplementation at different concentrations on lead toxicity in liver.
Topics: Animals; Antioxidants; Apoptosis; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Dietary Sup | 2007 |
Altered thiamine propyl disulfide metabolism in rats with liver injury induced by carbon tetrachloride and D-galactosamine.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochrome P-450 En | 1983 |
[Effect of thiamine on the formation of immune response in toxic lesions of the liver].
Topics: Animals; Antibody-Producing Cells; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver I | 1978 |
[Pharmacological study on thiamine triphosphate (TTP)].
Topics: Adenosine Triphosphatases; Animals; Anura; Blood Pressure; Carbon Tetrachloride; Cats; Cerebral Cort | 1967 |
Effect of CCl4 on the vitamin-protein profile of rat liver subcellular elements.
Topics: Animals; Ascorbic Acid; Biotin; Carbon Tetrachloride Poisoning; Centrifugation; Chemical and Drug In | 1970 |
[On some methods of treating toxic lesions of the liver].
Topics: Animals; Chemical and Drug Induced Liver Injury; Diathermy; Glutamates; Occupational Diseases; Rabbi | 1965 |
[Effect of vitamin B-1 and galascorbin on some indices of carbohydrate-phosphorus metabolism in the liver during toxic conditions].
Topics: Animals; Ascorbic Acid; Carbohydrate Metabolism; Carbon Tetrachloride Poisoning; Chemical and Drug I | 1965 |