Page last updated: 2024-10-20

thiamine and Brain Injuries

thiamine has been researched along with Brain Injuries in 15 studies

thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.

Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.

Research Excerpts

ExcerptRelevanceReference
" The three principal factors are: alcohol specific neurotoxicity, associated vitamin B1 (thiamine) deficiency (the Wernicke-Korsakoff syndrome) and liver failure secondary to alcoholic cirrhosis."4.79An introduction to alcohol-induced brain damage and its causes. ( Harper, C; Kril, J, 1994)
"There is increasing evidence for the role of thiamine deficiency in ethanol neurotoxicity and in development of alcoholic organic brain disorders other than Wernicke-Korsakoff syndrome [WKS] and cerebellar degeneration."4.79Thiamine utilization in the pathogenesis of alcohol-induced brain damage. ( Martin, PR; McCool, BA; Pekovich, SR; Singleton, CK; Whetsell, WO, 1994)
"Multiple events occur in the postcardiac arrest period, including excitotoxicity, mitochondrial dysfunction, and oxidative stress and inflammation, all of which contribute to ongoing brain injury and cellular death."2.82Pharmacologic neuroprotection in ischemic brain injury after cardiac arrest. ( Brosnahan, SB; Katz, A; Lam, JQ; Papadopoulos, J; Parnia, S, 2022)
"Asthenia is a key symptom of posttraumatic disorders (postcommotion syndrom)."2.73[The use of enerion in the treatment of asthenic disorders in patients after mild cranio-cerebral trauma]. ( Levin, OS; Slizkova, IuB, 2007)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's3 (20.00)18.2507
2000's2 (13.33)29.6817
2010's0 (0.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Katz, A1
Brosnahan, SB1
Papadopoulos, J1
Parnia, S1
Lam, JQ1
SCHAAL, W1
BARON, B1
HARTIG, W1
ZIMMERMANN, M1
RETHER, O1
Levin, OS1
Slizkova, IuB1
Harper, C1
Kril, J1
Bowden, S1
Bardenhagen, F1
Ambrose, M1
Whelan, G1
Martin, PR1
Pekovich, SR1
McCool, BA1
Whetsell, WO1
Singleton, CK1
Buylaert, WA1
Pincus, JH1
Solitare, GB1
Cooper, JR1
Fliege, K1
Mistler, O1
Robinson, N1
Torelli, L1

Reviews

4 reviews available for thiamine and Brain Injuries

ArticleYear
Pharmacologic neuroprotection in ischemic brain injury after cardiac arrest.
    Annals of the New York Academy of Sciences, 2022, Volume: 1507, Issue:1

    Topics: Animals; Antioxidants; Brain Injuries; Brain Ischemia; Heart Arrest; Humans; Memantine; Neuroprotect

2022
An introduction to alcohol-induced brain damage and its causes.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1994, Volume: 2

    Topics: Alcoholism; Animals; Brain; Brain Injuries; Ethanol; Humans; Liver Cirrhosis, Alcoholic; Organ Size;

1994
Thiamine utilization in the pathogenesis of alcohol-induced brain damage.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1994, Volume: 2

    Topics: Alcohol Amnestic Disorder; Alcoholism; Animals; Brain Injuries; Humans; Thiamine; Thiamine Deficienc

1994
Coma induced by intoxication.
    Acta neurologica Belgica, 2000, Volume: 100, Issue:4

    Topics: Accidental Falls; Alcohol-Induced Disorders, Nervous System; Alcoholic Intoxication; Antidotes; Brai

2000

Trials

3 trials available for thiamine and Brain Injuries

ArticleYear
[The use of enerion in the treatment of asthenic disorders in patients after mild cranio-cerebral trauma].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2007, Volume: 107, Issue:5

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Asthenia; Brain Injuries; Female; Humans; Male; Midd

2007
Alcohol, thiamin deficiency, and neuropsychological disorders.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1994, Volume: 2

    Topics: Adult; Alcohol Amnestic Disorder; Alcoholism; Brain Injuries; Cognition Disorders; Double-Blind Meth

1994
[Treatment of chronic painful conditions with a diazethylthiamine (fat-soluble vitamin B 1) combination preparation].
    Medizinische Klinik, 1966, Dec-30, Volume: 61, Issue:52

    Topics: Adult; Aged; Back Pain; Brain; Brain Injuries; Chronic Disease; Clinical Trials as Topic; Female; Hu

1966

Other Studies

8 other studies available for thiamine and Brain Injuries

ArticleYear
[Treatment of cerebral edema in fresh intracranial trauma].
    Die Medizinische, 1957, Feb-23, Issue:8

    Topics: Brain; Brain Edema; Brain Injuries; Craniocerebral Trauma; Edema; Plant Extracts; Thiamine

1957
[Supplementary therapy of traumatic brain injuries with vascular therapeutics].
    Therapie der Gegenwart, 1958, Volume: 97, Issue:12

    Topics: Anticoagulants; Brain; Brain Injuries; Flavonoids; Thiamine; Vitamins

1958
[Treatment of cerebral concussion with vitamin B1].
    Das Deutsche Gesundheitswesen, 1959, Mar-26, Volume: 14, Issue:13

    Topics: Brain; Brain Concussion; Brain Injuries; Humans; Thiamine

1959
[Contribution to the therapy of traumatic acute brain edema].
    Therapeutische Umschau. Revue therapeutique, 1962, Volume: 19

    Topics: Aesculus; Brain Edema; Brain Injuries; Humans; Intracranial Pressure; Thiamine

1962
[Venostasin treatment of disorders following brain concussion].
    Munchener medizinische Wochenschrift (1950), 1962, Apr-13, Volume: 104

    Topics: Brain; Brain Concussion; Brain Injuries; Drug Combinations; Escin; Humans; Plant Extracts; Thiamine

1962
Thiamine triphosphate levels and histopathology. Correlation in Leigh disease.
    Archives of neurology, 1976, Volume: 33, Issue:11

    Topics: Adult; Basal Ganglia; Brain Chemistry; Brain Injuries; Brain Neoplasms; Brain Stem; Central Nervous

1976
Enzyme response of traumatized tissue after intracortical injection into 5 day old rat brain.
    Journal of neurology, neurosurgery, and psychiatry, 1972, Volume: 35, Issue:6

    Topics: Acetylcholinesterase; Acid Phosphatase; Adenosine Triphosphatases; Animals; Animals, Newborn; Arachn

1972
[The use of aneurin in the postoperative period in patients undergoing brain surgery and in the medical treatment of patients with grave cranial injuries].
    Acta anaesthesiologica, 1965, Volume: 16

    Topics: Anesthesia; Brain; Brain Injuries; Neuroleptanalgesia; Postoperative Care; Thiamine

1965