Page last updated: 2024-10-20

thiamine and Brain Disorders

thiamine has been researched along with Brain Disorders in 74 studies

thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.

Research Excerpts

ExcerptRelevanceReference
"The effect of thiamine deficiency on rat brain DNA and RNA synthesis was investigated."7.65Reversible impairment of cerebral DNA synthesis in thiamine deficiency. ( Henderson, GI; Schenker, S, 1975)
"Extracts of tissue fluids from a patient with subacute necrotizing encephalomyelopathy inhibit thiamine pyrophosphate-adenosine triphosphate phosphotransferase of rat brain."7.65Thiamine triphosphate deficiency in subacute necrotizing encephalomyelopathy. ( Cooper, JR; Itokawa, Y; Pincus, JH, 1969)
"Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is the most prevalent encephalopathy in Japanese children."5.51Early administration of vitamins B1 and B6 and l-carnitine prevents a second attack of acute encephalopathy with biphasic seizures and late reduced diffusion: A case control study. ( Fukui, KO; Ishiguro, A; Kashii, H; Kubota, M; Terashima, H, 2019)
"In sub-Saharan Africa, the COVID-19 pandemic has caused severe malnutrition in elderly populations with the appearance of vitamin deficiencies, in particular thiamine responsible for Gayet Wernicke's encephalopathy (EGW)."4.31GAYET WERNICKE'S ENCEPHALOPATHY AFTER COVID-19 IN ELDERLY SUBJECTS IN TROPICAL ENVIRONMENTS: STUDY OF SIX (6) OBSERVATIONS IN CONAKRY. ( Camara, D; Cisse, A; Cisse, FA; Condé, K; Conde, S; Diakité, M; Diallo, MS; Diallo, SM; Kadji, JM; Kassa, DF; Lamah, E; Millimono, V; Othon, GC; Sakadi, F; Touré, A; Touré, ML, 2023)
"Thiamine deficiency is an uncommon cause of severe illness in the United States that can lead to significant morbidity because of high-output cardiac failure, peripheral neuropathy, and permanent neurologic impairment."4.02A BERIBERI UNHEALTHY LATTE: ENCEPHALOPATHY AND SHOCK FROM SEVERE NUTRITIONAL DEFICIENCY. ( Coyne, C; Hayden, SR; Lafree, A; Lasoff, D; Self, M; Signorelli, J; Wardi, G, 2021)
"To determine whether thiamine prophylaxis decreases the incidence of ifosfamide-induced encephalopathy in patients receiving ifosfamide for the treatment of lymphoma."3.96Evaluation of thiamine for the prevention of ifosfamide-induced encephalopathy. ( Ayarza, M; Clark, SM; Hairston, A; Lentz, KL; Liu, B; Morgan, KP; Wind, LS, 2020)
" This is a report of a 64-year-old female with relapsed double-hit diffuse large B-cell lymphoma who developed severe altered mental status and neurological symptoms after receiving a second dose of ifosfamide as part of her salvage standard dose R-IE (rituximab, ifosfamide, etoposide), in preparation for chimeric antigen receptor T-cell therapy."3.91Hydration, methylene blue, and thiamine as a prevention regimen for ifosfamide-induced encephalopathy. ( Gharaibeh, EZ; Powers, BC; Salacz, ME; Telfah, M, 2019)
"A Medline search using the terms 'thiamine deficiency' and 'formula' or 'feeding' without year limit identified relevant published data on that event."3.78Thiamine-deficient infant formula: what happened and what have we learned? ( Shamir, R, 2012)
"Infantile encephalitic beriberi (IEBB) is a rare form of thiamine deficiency and is poorly described."3.74High prevalence of infantile encephalitic beriberi with overlapping features of Leigh's disease. ( Chandak, GR; Kumar, MV; Madap, K; Mani, S; Rao, SN; Singh, L, 2008)
" Long fasting, hyperemesis and total parenteral nutrition (TPN) without thiamine are main causes of thiamine deficiency in the course of pancreatitis."3.73Pancreatic encephalopathy and Wernicke encephalopathy in association with acute pancreatitis: a clinical study. ( Cheng, LF; Huang, XS; Liu, QS; Sun, GH; Yang, YS, 2006)
"Ethylene glycol toxicity has produced central nervous system abnormalities including coma, cerebral edema, and cranial nerve dysfunction."3.70Ethylene glycol ingestion resulting in brainstem and midbrain dysfunction. ( Follmer, R; Ford, MD; Morgan, BW, 2000)
"For observing biochemical and morphopathological changes in experimental cerebrocortical necrosis, 6 sheep and 6 calves were given amprolium (600 mg/kg/day)."3.69Biochemical and pathological findings on sheep and calves dying of experimental cerebrocortical necrosis. ( Hirano, K; Horino, R; Itabisashi, T, 1994)
"For observing chronological changes of biochemical and pathological aspects in experimental cerebrocortical necrosis, 14 sheep were given amprolium (600 mg/kg/day), and killed at various clinical stages."3.69Biochemical and pathological observations on sheep showing various clinical manifestations of experimental cerebrocortical necrosis. ( Hirano, K; Horino, R; Itabisashi, T, 1994)
"The effect of thiamine deficiency on rat brain DNA and RNA synthesis was investigated."3.65Reversible impairment of cerebral DNA synthesis in thiamine deficiency. ( Henderson, GI; Schenker, S, 1975)
"Extracts of tissue fluids from a patient with subacute necrotizing encephalomyelopathy inhibit thiamine pyrophosphate-adenosine triphosphate phosphotransferase of rat brain."3.65Thiamine triphosphate deficiency in subacute necrotizing encephalomyelopathy. ( Cooper, JR; Itokawa, Y; Pincus, JH, 1969)
"We describe an episode of encephalopathy developed at the third cycle of ifosfamide treatment in a child with Ewing sarcoma."1.72Ifosfamide-induced Encephalopathy With Rapid Response to Thiamine: A Pediatric Case. ( Anlar, B; Aydin, B; Günbey, C; Müngen, E; Öz, S; Yaman Bajin, İ, 2022)
"Treatment with thiamine while awaiting the outcome of diagnostic tests may be a good choice."1.72Case report of two affected siblings in a family with thiamine metabolism dysfunction syndrome 5: a rare, but treatable neurodegenerative disease. ( Chen, H; Chen, Y; Huang, Z; Li, X; Sun, X; Xie, J; Yi, Z; Yu, X; Zhong, J, 2022)
"We report three cases of encephalopathy from two unrelated pedigrees with basal ganglia signal changes after fever of unknown origin."1.62Identification and functional analysis of novel SLC25A19 variants causing thiamine metabolism dysfunction syndrome 4. ( Chen, Y; Fang, B; Fang, K; Guo, J; Guo, R; Hao, C; Hu, X; Li, W; Ni, J; Qian, S, 2021)
"Metronidazole was stopped."1.56Isolated involvement of corpus callosum in metronidazole-induced encephalopathy with concomitant peripheral neuropathy: A case report. ( Liu, S; Peng, Q; You, Q; Zhang, J, 2020)
"The patients presented with subacute encephalopathy between the ages of 1-27 months."1.56Eleven novel mutations and clinical characteristics in seven Chinese patients with thiamine metabolism dysfunction syndrome. ( Dong, H; Guan, H; Jin, Y; Kang, L; Li, D; Li, X; Liu, Y; Song, J; Yang, Y; Zhang, Y; Zhou, C, 2020)
"Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is the most prevalent encephalopathy in Japanese children."1.51Early administration of vitamins B1 and B6 and l-carnitine prevents a second attack of acute encephalopathy with biphasic seizures and late reduced diffusion: A case control study. ( Fukui, KO; Ishiguro, A; Kashii, H; Kubota, M; Terashima, H, 2019)
"Metformin was withheld and signs and symptoms quickly resolved."1.48Metformin-induced encephalopathy: the role of thiamine. ( Bynevelt, M; Franconi, C; McGarvey, C; Prentice, D, 2018)
"Pancreatic encephalopathy (PE), an unfamiliar complication of severe acute pancreatitis (SAP), is difficult to diagnose and treat, and it has a high mortality."1.32Pancreatic encephalopathy in 24 patients with severe acute pancreatitis. ( Ding, X; Gong, JP; Li, SW; Liu, CA, 2004)
"Four patients with classical maple syrup urine disease were treated for up to 5885 days per patient with a relaxed protocol allowing branched-chain amino acid levels in plasma to rise about 5 times the normal mean value."1.28Maple syrup urine disease: interrelations between branched-chain amino-, oxo- and hydroxyacids; implications for treatment; associations with CNS dysmyelination. ( Chitayat, D; Clow, CL; Mamer, OA; Reade, TR; Scriver, CR; Treacy, E, 1992)
"1 patient with Wernicke syndrome showed a remarkable improvement of saccadic velocity following thiamine administration."1.26[Slowed saccades in various neurological disorders]. ( Hamann, KU, 1979)
"Thiamine-deficient encephalopathy is characterized by morphologic lesions in the brainstem and less extensively in the cerebellum, but the early neurologic signs reverse rapidly and fully with thiamine, indicating a metabolic disorder."1.25Encephalopathy of thiamine deficieny: studies of intracerebral mechanisms. ( Cook, M; McCandless, DW; Schenker, S, 1968)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-199038 (51.35)18.7374
1990's5 (6.76)18.2507
2000's8 (10.81)29.6817
2010's11 (14.86)24.3611
2020's12 (16.22)2.80

Authors

AuthorsStudies
Chen, Y2
Fang, B1
Hu, X1
Guo, R1
Guo, J1
Fang, K1
Ni, J1
Li, W1
Qian, S1
Hao, C1
C, S1
Kundana, PK1
Reddy, N1
Reddy B, S1
Poddutoor, P1
Rizwan, A1
Konanki, R1
Samur, BM1
Gümüş, G1
Canpolat, M1
Gümüş, H1
Per, H1
Cağlayan, AO1
Müngen, E1
Yaman Bajin, İ1
Öz, S1
Günbey, C1
Anlar, B1
Aydin, B1
Li, X2
Huang, Z1
Sun, X1
Yi, Z1
Xie, J1
Yu, X1
Chen, H1
Zhong, J1
Touré, ML1
Othon, GC1
Touré, A1
Diakité, M1
Condé, K1
Kassa, DF1
Sakadi, F1
Camara, D1
Conde, S1
Millimono, V1
Diallo, MS1
Diallo, SM1
Kadji, JM1
Lamah, E1
Cisse, FA1
Cisse, A1
Bottega, R1
Perrone, MD1
Vecchiato, K1
Taddio, A1
Sabui, S1
Pecile, V1
Said, HM1
Faletra, F1
Zhu, B1
Wu, J1
Chen, G1
Chen, L1
Yao, Y1
Peng, Q1
You, Q1
Zhang, J1
Liu, S1
Li, D1
Song, J1
Liu, Y2
Dong, H1
Kang, L1
Zhang, Y1
Jin, Y1
Guan, H1
Zhou, C1
Yang, Y1
Plecko, B1
Self, M1
Signorelli, J1
Lasoff, D1
Lafree, A1
Coyne, C1
Hayden, SR1
Wardi, G1
Suzuki, K1
Yamada, K1
Fukuhara, Y1
Tsuji, A1
Shibata, K1
Wakamatsu, N1
McGarvey, C1
Franconi, C1
Prentice, D1
Bynevelt, M1
Gharaibeh, EZ1
Telfah, M1
Powers, BC1
Salacz, ME1
Stevanović, V1
Barušić, Z1
Višković, K1
Rode, OĐ1
Tešović, G1
Huang, W1
Qin, J1
Liu, D1
Wang, Y1
Shen, X1
Yang, N1
Zhou, H1
Cai, XT1
Wang, ZL1
Yu, D1
Luo, R1
Sun, Q1
Xie, YM1
Jia, D1
Fukui, KO1
Kubota, M1
Terashima, H1
Ishiguro, A1
Kashii, H1
Lentz, KL1
Clark, SM1
Ayarza, M1
Liu, B1
Morgan, KP1
Wind, LS1
Hairston, A1
Sechi, E1
Addis, A1
Fadda, G1
Minafra, L1
Bravatà, V1
Sechi, G1
Bateman, K1
Kobayashi, Z1
Tsuchiya, K1
Takahashi, M1
Yokota, O1
Taki, K1
Ishizu, H1
Arai, T1
Akiyama, H1
Mizusawa, H1
Shamir, R1
Lerner, EB1
Billittier, AJ1
Lance, DR1
Janicke, DM1
Teuscher, JA1
BETKE, K1
GADEKE, R2
PERON, N1
SUKHORUKOVA, LI1
Buesa, JM1
García-Teijido, P1
Losa, R1
Fra, J1
MARTIN, C1
LISSAK, K1
Ding, X1
Liu, CA1
Gong, JP1
Li, SW1
Sun, GH1
Yang, YS1
Liu, QS1
Cheng, LF1
Huang, XS1
Kukulska-Pawluczuk, B1
Princ, R1
Burzyńska-Makuch, M1
Borkowska, A1
Höltershinken, M1
Höhling, A1
Witte, B1
Scholz, H1
URBANITZKY, E1
Rao, SN1
Mani, S1
Madap, K1
Kumar, MV1
Singh, L1
Chandak, GR1
Pill, AH2
Davies, ET1
Collings, DF1
Venn, JA1
Buckle, RM1
Aikawa, H2
Watanabe, IS1
Furuse, T1
Iwasaki, Y2
Satoyoshi, E1
Sumi, T1
Moroji, T1
Eigenmann, UJ1
Martens, J1
Clausen, HH1
Narabayashi, H1
Watanabe, I1
Horino, R3
Itabisashi, T3
Hirano, K3
Alves de Oliveira, L1
Jean-Blain, C1
Komisarczuk-Bony, S1
Durix, A1
Durier, C1
Morgan, BW1
Ford, MD1
Follmer, R1
Cooper, JR3
Pincus, JH3
Hamann, KU1
Höller, H1
Schaller, K1
Behrens, H1
Dreyfus, PM1
Spivak, JL1
Jackson, DL1
Loew, FM1
Lilja, CG1
Henderson, GI1
Schenker, S2
Treacy, E1
Clow, CL1
Reade, TR1
Chitayat, D1
Mamer, OA1
Scriver, CR1
Maeda, M1
Butterworth, RF1
Héroux, M1
Pluvinage, R1
Deutsch, K1
Freund, G1
Lonsdale, D1
Price, JW1
Shchurevskiĭ, VE1
Kudriavtsev, AA1
Valenti, F1
D'Alessandro, R1
Itokawa, Y2
Piros, K1
Edwin, EE1
Jackman, R1
Goryd, V1
Lesh, D1
McCandless, DW1
Cook, M1
Caccuri, S1
Fati, S1
Cole, M1
Turner, A1
Frank, O1
Baker, H1
Leevy, CM1
Thompson, RA1
Lynde, RH1
Ebels, EJ1
Blokzijl, EJ1
Troelstra, JA1
Leonhard, K1
Zeller, HJ1

Reviews

5 reviews available for thiamine and Brain Disorders

ArticleYear
Clinical and genetic studies of thiamine metabolism dysfunction syndrome-4: case series and review of the literature.
    Clinical dysmorphology, 2022, Jul-01, Volume: 31, Issue:3

    Topics: Brain Diseases; Exome Sequencing; Humans; Mitochondrial Membrane Transport Proteins; Mutation; Polyn

2022
Thiamine and the nervous system: an overview.
    Journal of nutritional science and vitaminology, 1976, Volume: 22 SUPPL

    Topics: Action Potentials; Animals; Brain Diseases; Central Nervous System; Humans; Membranes; Nervous Syste

1976
A thiamin-responsive polioencephalomalacia in tropicaland nontropical livestock production systems-1.
    World review of nutrition and dietetics, 1975, Volume: 20

    Topics: Agriculture; Animal Diseases; Animal Nutritional Physiological Phenomena; Animals; Brain; Brain Dise

1975
Chronic central nervous system toxicity of alcohol.
    Annual review of pharmacology, 1973, Volume: 13

    Topics: Alcohol Amnestic Disorder; Alcoholism; Animals; Behavior, Animal; Brain; Brain Diseases; Central Ner

1973
[Cerebrocortical necrosis in cattle and sheep (review of the literature)].
    Veterinariia, 1970, Volume: 46, Issue:4

    Topics: Animals; Brain Diseases; Cattle; Cattle Diseases; Cerebral Cortex; Necrosis; Sheep; Sheep Diseases;

1970

Trials

1 trial available for thiamine and Brain Disorders

ArticleYear
Can paramedics safely treat and discharge hypoglycemic patients in the field?
    The American journal of emergency medicine, 2003, Volume: 21, Issue:2

    Topics: Brain Diseases; Consent Forms; Diabetes Mellitus, Type 1; Emergency Medical Services; Emergency Medi

2003

Other Studies

68 other studies available for thiamine and Brain Disorders

ArticleYear
Identification and functional analysis of novel SLC25A19 variants causing thiamine metabolism dysfunction syndrome 4.
    Orphanet journal of rare diseases, 2021, 09-29, Volume: 16, Issue:1

    Topics: Brain Diseases; Humans; Membrane Transport Proteins; Mitochondrial Membrane Transport Proteins; Muta

2021
Thiamine-responsive, life-threatening, pulmonary hypertensive crisis with encephalopathy in young infants: A case series.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2022, Volume: 36

    Topics: Beriberi; Brain Diseases; Breast Feeding; Female; Humans; Infant; Thiamine; Thiamine Deficiency

2022
Ifosfamide-induced Encephalopathy With Rapid Response to Thiamine: A Pediatric Case.
    Journal of pediatric hematology/oncology, 2022, 10-01, Volume: 44, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Diseases; Child; Cisplatin; Creatinine; Humans; Ifosfamide;

2022
Case report of two affected siblings in a family with thiamine metabolism dysfunction syndrome 5: a rare, but treatable neurodegenerative disease.
    BMC neurology, 2022, Sep-29, Volume: 22, Issue:1

    Topics: Ataxia; Brain Diseases; Humans; Male; Muscle Hypotonia; Mutation; Neurodegenerative Diseases; Siblin

2022
GAYET WERNICKE'S ENCEPHALOPATHY AFTER COVID-19 IN ELDERLY SUBJECTS IN TROPICAL ENVIRONMENTS: STUDY OF SIX (6) OBSERVATIONS IN CONAKRY.
    Georgian medical news, 2023, Issue:334

    Topics: Aged; Brain Diseases; COVID-19; Guinea; Humans; Malnutrition; Pandemics; Thiamine; Wernicke Encephal

2023
Functional analysis of the third identified SLC25A19 mutation causative for the thiamine metabolism dysfunction syndrome 4.
    Journal of human genetics, 2019, Volume: 64, Issue:11

    Topics: Adolescent; Brain Diseases; Genetic Predisposition to Disease; Humans; Male; Microcephaly; Mitochond

2019
Whole Exome Sequencing Identifies a Novel Mutation of TPK1 in a Chinese Family with Recurrent Ataxia.
    Journal of molecular neuroscience : MN, 2020, Volume: 70, Issue:8

    Topics: Ataxia; Binding Sites; Brain Diseases; Child, Preschool; Exome Sequencing; Genetic Testing; Humans;

2020
Isolated involvement of corpus callosum in metronidazole-induced encephalopathy with concomitant peripheral neuropathy: A case report.
    Medicine, 2020, Volume: 99, Issue:20

    Topics: Adult; Aged; Antiprotozoal Agents; Brain Diseases; Corpus Callosum; Dysentery, Amebic; Humans; Magne

2020
Eleven novel mutations and clinical characteristics in seven Chinese patients with thiamine metabolism dysfunction syndrome.
    European journal of medical genetics, 2020, Volume: 63, Issue:10

    Topics: Asian People; Biotin; Brain; Brain Diseases; Child, Preschool; DNA, Mitochondrial; Female; High-Thro

2020
TPK1 Deficiency-A Vitamin-Responsive Encephalopathy with a Suggestive MRI Pattern.
    Neuropediatrics, 2021, Volume: 52, Issue:2

    Topics: Brain Diseases; Humans; Infant; Magnetic Resonance Imaging; Thiamine; Vitamins

2021
A BERIBERI UNHEALTHY LATTE: ENCEPHALOPATHY AND SHOCK FROM SEVERE NUTRITIONAL DEFICIENCY.
    The Journal of emergency medicine, 2021, Volume: 61, Issue:3

    Topics: Adult; Beriberi; Brain Diseases; Female; Humans; Malnutrition; Middle Aged; Thiamine; Thiamine Defic

2021
High-dose thiamine prevents brain lesions and prolongs survival of Slc19a3-deficient mice.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Animals; Brain Diseases; Dose-Response Relationship, Drug; Humans; Membrane Transport Proteins; Mice

2017
Metformin-induced encephalopathy: the role of thiamine.
    Internal medicine journal, 2018, Volume: 48, Issue:2

    Topics: Adult; Brain Diseases; Diabetic Nephropathies; Female; Humans; Hypoglycemic Agents; Metformin; Thiam

2018
Hydration, methylene blue, and thiamine as a prevention regimen for ifosfamide-induced encephalopathy.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2019, Volume: 25, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Etoposide; Female; Humans; Ifosfamid

2019
Acute necrotizing encephalopathy of childhood associated with human herpes virus 6 in Croatia.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2019, Volume: 40, Issue:3

    Topics: Brain Diseases; Croatia; Herpesvirus 6, Human; Humans; Infant; Influenza, Human; Magnetic Resonance

2019
Reduced thiamine binding is a novel mechanism for TPK deficiency disorder.
    Molecular genetics and genomics : MGG, 2019, Volume: 294, Issue:2

    Topics: Amino Acid Sequence; Brain Diseases; Child, Preschool; China; Female; Homozygote; Humans; Male; Muta

2019
Early administration of vitamins B1 and B6 and l-carnitine prevents a second attack of acute encephalopathy with biphasic seizures and late reduced diffusion: A case control study.
    Brain & development, 2019, Volume: 41, Issue:7

    Topics: Brain Diseases; Carnitine; Case-Control Studies; Child, Preschool; Diagnosis, Differential; Disease

2019
Evaluation of thiamine for the prevention of ifosfamide-induced encephalopathy.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2020, Volume: 26, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Carboplatin; Cohort Studies; Etoposi

2020
Teaching NeuroImages: Subacute encephalopathy in a young woman with THTR2 gene mutation.
    Neurology, 2015, Oct-06, Volume: 85, Issue:14

    Topics: Brain; Brain Diseases; Female; Humans; Membrane Transport Proteins; Mutation; Thiamine; Treatment Ou

2015
Encephalopathy caused by thiamine deficiency.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2015, Volume: 105, Issue:7

    Topics: Administration, Intravenous; Brain Diseases; Creatine Kinase; Dyspnea, Paroxysmal; Female; Humans; P

2015
Morel's laminar sclerosis showing apraxia of speech: distribution of cortical lesions in an autopsy case.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2010, Feb-01, Volume: 30, Issue:1

    Topics: Alcoholism; Apraxias; Autopsy; Brain; Brain Diseases; Chronic Disease; Fatal Outcome; Humans; Male;

2010
Thiamine-deficient infant formula: what happened and what have we learned?
    Annals of nutrition & metabolism, 2012, Volume: 60, Issue:3

    Topics: Brain Diseases; Food Industry; Germany; Humans; Infant; Infant Formula; Israel; MEDLINE; Quality Con

2012
[Treatment of severe acute cerebral symptoms in young children].
    Arztliche Wochenschrift, 1955, Sep-09, Volume: 10, Issue:36

    Topics: Brain; Brain Diseases; Plants; Thiamine

1955
[The treatment of brain diseases and neurologic complications of chronic alcoholism by the combination of strychnal and massive doses of vitamin B1].
    Clinique (Paris, France), 1963, Volume: 58

    Topics: Alcoholism; Brain Diseases; Humans; Nervous System Diseases; Neurologic Manifestations; Strychnine;

1963
[MARCHIAFAVA-BIGNAMI SYNDROME IN EXPERIMENTAL CHRONIC ALCOHOLISM].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1964, Volume: 64

    Topics: Alcoholic Intoxication; Alcoholism; Brain Diseases; Corpus Callosum; Dogs; Marchiafava-Bignami Disea

1964
[Further experimental studies on the permeability of cerebral vessels after administration of ACTH and its response to vasoconstrictive and hypotensive substances; a tentative model for therapy of brain edema and so-called serous encephalitis].
    Zeitschrift fur Kinderheilkunde, 1954, Volume: 75, Issue:5

    Topics: Adrenocorticotropic Hormone; Autonomic Agents; Blood-Brain Barrier; Brain; Brain Diseases; Brain Ede

1954
Treatment of ifosfamide encephalopathy with intravenous thiamin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Oct-01, Volume: 9, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Diseases; Humans; Ifosfamide; Infusions, Intravenous

2003
The aneurine content of the nerves of B1-avitaminotic and normal rats.
    Zeitschrift fur Vitamin-, Hormon- und Fermentforschung, 1950, Volume: 3, Issue:5-6

    Topics: Animals; Avitaminosis; Brain Diseases; Nervous System; Rats; Sciatic Nerve; Thiamine

1950
Pancreatic encephalopathy in 24 patients with severe acute pancreatitis.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2004, Volume: 3, Issue:4

    Topics: Acute Disease; Adult; Aged; Brain Diseases; Female; Humans; Incidence; Male; Middle Aged; Pancreatit

2004
Pancreatic encephalopathy and Wernicke encephalopathy in association with acute pancreatitis: a clinical study.
    World journal of gastroenterology, 2006, Jul-14, Volume: 12, Issue:26

    Topics: Acute Disease; Adult; Brain Diseases; Brain Diseases, Metabolic; Diagnosis, Differential; Female; Hu

2006
[Marchiafava-Bignami disease].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2006, Volume: 59, Issue:7-8

    Topics: Adult; Alcohol-Induced Disorders, Nervous System; Alcoholism; Brain Diseases; Corpus Callosum; Demye

2006
[Thiamine and its derivates in cattle blood measured by HPLC in healthy animals, in patients suffering from CCN and in their cohorts].
    DTW. Deutsche tierarztliche Wochenschrift, 2007, Volume: 114, Issue:6

    Topics: Animals; Brain Diseases; Cattle; Cattle Diseases; Cerebral Cortex; Chromatography, High Pressure Liq

2007
About the treatment of encephalopathies with high doses of vitamin B1.
    Wiener klinische Wochenschrift, 1949, Aug-12, Volume: 61, Issue:32

    Topics: Brain; Brain Diseases; Thiamine; Thiazoles

1949
High prevalence of infantile encephalitic beriberi with overlapping features of Leigh's disease.
    Journal of tropical pediatrics, 2008, Volume: 54, Issue:5

    Topics: Beriberi; Brain Diseases; Diagnosis, Differential; Female; Follow-Up Studies; Hospitals, Teaching; H

2008
The experimental reproduction of lesions of cerebrocortical necrosis in a calf.
    The Veterinary record, 1966, May-21, Volume: 78, Issue:21

    Topics: Animals; Antimetabolites; Brain Diseases; Cattle; Cattle Diseases; Cerebral Cortex; Necrosis; Thiami

1966
Wernicke's encephalopathy: studies on blood pyruvic acid and alpha-ketoglutaric acids.
    Acta neurologica Scandinavica, 1967, Volume: 43, Issue:2

    Topics: Adult; Alcoholism; Brain Diseases; Chromatography; Glucose; Humans; Ketoglutaric Acids; Male; Middle

1967
Evidence of thiamine deficiency in calves affected with cerebrocortical necrosis.
    The Veterinary record, 1967, Aug-19, Volume: 81, Issue:8

    Topics: Animals; Brain Chemistry; Brain Diseases; Cattle; Cattle Diseases; Cerebral Cortex; Glucose; Liver;

1967
Low energy levels in thiamine-deficient encephalopathy.
    Journal of neuropathology and experimental neurology, 1984, Volume: 43, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Brain Diseases; Disease Models, Animal; Energy Metabolism; Male; M

1984
[Differential diagnosis of lead encephalopathy, cerebrocortical necrosis and infectious septisemic thrombosing meningoencephalitis in cattle].
    Tierarztliche Praxis, 1982, Volume: 10, Issue:1

    Topics: Animals; Brain Diseases; Cattle; Cattle Diseases; Diagnosis, Differential; Encephalomalacia; Female;

1982
[An experimental study of pyrithiamine-induced encephalopathy in the rat. I. Clinical observation and the determination of the concentrations of thiamine in the brain and the blood (author's transl)].
    Rinsho shinkeigaku = Clinical neurology, 1981, Volume: 21, Issue:9

    Topics: Animals; Brain Chemistry; Brain Diseases; Male; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbr

1981
Biochemical and pathological findings on sheep and calves dying of experimental cerebrocortical necrosis.
    The Journal of veterinary medical science, 1994, Volume: 56, Issue:3

    Topics: Amprolium; Animals; Brain Diseases; Cattle; Cerebral Cortex; Electroencephalography; Erythrocytes; F

1994
Biochemical and pathological observations on sheep showing various clinical manifestations of experimental cerebrocortical necrosis.
    The Journal of veterinary medical science, 1994, Volume: 56, Issue:3

    Topics: Amprolium; Animals; Brain; Brain Diseases; Cerebral Cortex; Electroencephalography; Female; Liver; M

1994
Microbial thiamin metabolism in the rumen simulating fermenter (RUSITEC): the effect of acidogenic conditions, a high sulfur level and added thiamin.
    The British journal of nutrition, 1997, Volume: 78, Issue:4

    Topics: Animals; Bacteria; Brain Diseases; Hydrogen-Ion Concentration; Models, Biological; Rumen; Ruminants;

1997
Ethylene glycol ingestion resulting in brainstem and midbrain dysfunction.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:4

    Topics: Acute Kidney Injury; Adult; Arrhythmias, Cardiac; Brain Diseases; Brain Edema; Brain Stem; Calcium G

2000
The role of thiamine in nervous tissue.
    Neurochemical research, 1979, Volume: 4, Issue:2

    Topics: Animals; Brain; Brain Diseases; Cattle; Coenzymes; Fishes; Ketoglutarate Dehydrogenase Complex; Nerv

1979
[Slowed saccades in various neurological disorders].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1979, Volume: 178, Issue:6

    Topics: Aged; Brain Diseases; Child; Electrooculography; Eye Movements; Humans; Huntington Disease; Male; Mi

1979
[In-vitro vitamin-B1-inactivating effect of plant feed materials].
    DTW. Deutsche tierarztliche Wochenschrift, 1976, Mar-05, Volume: 83, Issue:3

    Topics: Animal Feed; Animals; Brain Diseases; Cattle; Cattle Diseases; Sheep; Sheep Diseases; Thiamine

1976
Pellagra: an analysis of 18 patients and a review of the literature.
    The Johns Hopkins medical journal, 1977, Volume: 140, Issue:6

    Topics: Adult; Aged; Alcoholism; Brain Diseases; Dermatitis; Diarrhea; Female; Humans; Male; Middle Aged; Ne

1977
Pyrimidinyl nicotinic acid and cerebrocortical necrosis.
    Acta veterinaria Scandinavica, 1975, Volume: 16, Issue:1

    Topics: Animals; Brain Diseases; Cattle; Cerebral Cortex; Necrosis; Nicotinic Acids; Pyrimidines; Rats; Thia

1975
Reversible impairment of cerebral DNA synthesis in thiamine deficiency.
    The Journal of laboratory and clinical medicine, 1975, Volume: 86, Issue:1

    Topics: Adenine; Animals; Brain; Brain Diseases; Carbon Radioisotopes; DNA; Female; Hypothermia; Organ Size;

1975
Maple syrup urine disease: interrelations between branched-chain amino-, oxo- and hydroxyacids; implications for treatment; associations with CNS dysmyelination.
    Journal of inherited metabolic disease, 1992, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Amino Acids, Branched-Chain; Brain Diseases; Child; Female; Humans; Maple Syrup U

1992
Electroencephalographic observation on sheep and cattle with experimental cerebrocortical necrosis.
    Nihon juigaku zasshi. The Japanese journal of veterinary science, 1990, Volume: 52, Issue:3

    Topics: Amprolium; Animals; Brain Diseases; Cattle; Cattle Diseases; Cerebral Cortex; Electrodes, Implanted;

1990
Effect of pyrithiamine treatment and subsequent thiamine rehabilitation on regional cerebral amino acids and thiamine-dependent enzymes.
    Journal of neurochemistry, 1989, Volume: 52, Issue:4

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Diseases; Glutamates; Glutamic Acid; Keto

1989
[Study of the therapeutic action of a combination of vitamins B1, B6 and hydroxocobalamin in large doses].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1968, Jan-20, Volume: 44, Issue:4

    Topics: Adult; Aged; Anemia; Brain Diseases; Epilepsy; Facial Paralysis; Fatty Liver; Female; Hemiplegia; He

1968
An electron microscopical study of the cerebral cortex of the calf. II. The calf with amprolium-induced cerebrocortical necrosis.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1973, Volume: 20, Issue:8

    Topics: Amprolium; Animals; Antiprotozoal Agents; Axons; Brain Diseases; Cattle; Cattle Diseases; Cell Membr

1973
Pyruvic aciduria in the detection of thiamine responsive encephalopathy.
    Cleveland Clinic quarterly, 1973,Summer, Volume: 40, Issue:2

    Topics: Brain Diseases; Child; Female; Humans; Infant; Male; Pyruvates; Thiamine; Thiamine Deficiency

1973
[On the use of high doses of thiamine in anesthesia in neurosurgery].
    Minerva neurochirurgica, 1969, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia; Brain Diseases; Brain Neoplasms; Child; Female; Humans; Interve

1969
Experience with phosphoryl transferase inhibition in subacute necrotizing encephalomyelopathy.
    The New England journal of medicine, 1970, Oct-08, Volume: 283, Issue:15

    Topics: Adenosine Triphosphate; Brain; Brain Chemistry; Brain Diseases; Child; Esters; Glycoproteins; Humans

1970
Thiaminase I in the development of cerebrocortical necrosis in sheep and cattle.
    Nature, 1970, Nov-21, Volume: 228, Issue:5273

    Topics: Animals; Biological Assay; Brain Chemistry; Brain Diseases; Cattle; Cattle Diseases; Rumen; Sheep; S

1970
[Clinico-electroencephalographic correlations in Wernicke's encephalopathy with Korsakoff's syndrome].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1967, Volume: 67, Issue:2

    Topics: Alcohol Amnestic Disorder; Alcoholism; Brain Diseases; Cerebral Hemorrhage; Electroencephalography;

1967
Encephalopathy of thiamine deficieny: studies of intracerebral mechanisms.
    The Journal of clinical investigation, 1968, Volume: 47, Issue:10

    Topics: Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Brain Diseases; Carbon Isotopes; Carboxy-Ly

1968
[Pathology caused by tri-orthocresylphosphate. Experimental research].
    Minerva medica, 1968, Sep-29, Volume: 59, Issue:78

    Topics: Animals; Brain Diseases; Cholinesterases; Cresols; Electroencephalography; Electrolytes; Electromyog

1968
Insect repellents.
    The Medical letter on drugs and therapeutics, 1968, Jul-12, Volume: 10, Issue:14

    Topics: Brain Diseases; Child, Preschool; Dermatitis, Contact; Eye Diseases; Female; Humans; Insect Bites an

1968
Extraocular palsy and thiamine therapy in Wernicke's encephalopathy.
    The American journal of clinical nutrition, 1969, Volume: 22, Issue:1

    Topics: Adult; Alcoholism; Brain Diseases; Erythrocytes; Eye Manifestations; Humans; Ketones; Liver Cirrhosi

1969
Thiamine triphosphate deficiency in subacute necrotizing encephalomyelopathy.
    Science (New York, N.Y.), 1969, Apr-04, Volume: 164, Issue:3875

    Topics: Animals; Brain; Brain Diseases; Cerebellum; Child; Child, Preschool; Frontal Lobe; Humans; Kidney; L

1969
Convergence spasm associated with Wernicke's encephalopathy.
    Neurology, 1969, Volume: 19, Issue:7

    Topics: Accommodation, Ocular; Adult; Brain Diseases; Chlordiazepoxide; Female; Humans; Spasm; Thiamine; Vit

1969
A Wernicke-like encephalomyelopathy in children (Leigh), an inborn error of metabolism? Report of 5 cases with emphasis on its familial incidence.
    Helvetica paediatrica acta, 1965, Volume: 20, Issue:3

    Topics: Brain Diseases; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Metabolism,

1965
[Puberity emaciation sickness with symptomatic psychosis].
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1966, Volume: 98, Issue:1

    Topics: Adolescent; Ascorbic Acid; Brain Diseases; Electroencephalography; Emaciation; Female; Humans; Psych

1966