Page last updated: 2024-10-20

thiamine and Bowel Diseases, Inflammatory

thiamine has been researched along with Bowel Diseases, Inflammatory in 10 studies

thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.

Research Excerpts

ExcerptRelevanceReference
"We found no beneficial effect on fatigue from thiamine taken in doses of 300 mg per day for 12 weeks following high-dose treatment."9.51Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study. ( Bager, P; Dahlerup, JF; Hvas, CL; Rud, CL, 2022)
"To demonstrate that fatigue and other disorders related to ulcerative colitis and Crohn's disease are the manifestation of an intracellular mild thiamine deficiency and not due to malabsorbtion, augmented requirements, or nutritional factors, and that this dysfunction is curable with high doses of thiamine administered orally or parenterally."7.79Thiamine and fatigue in inflammatory bowel diseases: an open-label pilot study. ( Costantini, A; Pala, MI, 2013)
"We found no beneficial effect on fatigue from thiamine taken in doses of 300 mg per day for 12 weeks following high-dose treatment."5.51Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study. ( Bager, P; Dahlerup, JF; Hvas, CL; Rud, CL, 2022)
"To demonstrate that fatigue and other disorders related to ulcerative colitis and Crohn's disease are the manifestation of an intracellular mild thiamine deficiency and not due to malabsorbtion, augmented requirements, or nutritional factors, and that this dysfunction is curable with high doses of thiamine administered orally or parenterally."3.79Thiamine and fatigue in inflammatory bowel diseases: an open-label pilot study. ( Costantini, A; Pala, MI, 2013)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (20.00)24.3611
2020's8 (80.00)2.80

Authors

AuthorsStudies
Bager, P5
Hvas, CL4
Rud, CL3
Dahlerup, JF4
Vitali, R1
Prioreschi, C1
Lorenzo Rebenaque, L1
Colantoni, E1
Giovannini, D1
Frusciante, S1
Diretto, G1
Marco-Jiménez, F1
Mancuso, M1
Casciati, A1
Pazzaglia, S1
Hansen, MM1
Ueland, P1
LeBlanc, JF1
Hart, AL1
Hvas, C1
Rud, C1
Dahlerup, J1
Lubell, JM1
Ghishan, FK1
Kiela, PR1
Costantini, A1
Pala, MI1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Thiamin Against Robust IBD Fatigue[NCT03634735]Phase 440 participants (Actual)Interventional2018-11-27Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for thiamine and Bowel Diseases, Inflammatory

ArticleYear
Vitamins and Minerals in Inflammatory Bowel Disease.
    Gastroenterology clinics of North America, 2017, Volume: 46, Issue:4

    Topics: Anemia, Iron-Deficiency; Animals; Avitaminosis; Biotin; Calcium; Cholecalciferol; Dietary Supplement

2017

Trials

3 trials available for thiamine and Bowel Diseases, Inflammatory

ArticleYear
Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Scandinavian journal of gastroenterology, 2022, Volume: 57, Issue:1

    Topics: Chronic Disease; Colitis; Fatigue; Humans; Inflammatory Bowel Diseases; Thiamine

2022
B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Molecular medicine (Cambridge, Mass.), 2023, 10-25, Volume: 29, Issue:1

    Topics: Fatigue Syndrome, Chronic; Humans; Inflammatory Bowel Diseases; Riboflavin; Thiamine; Vitamin B Comp

2023
Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Alimentary pharmacology & therapeutics, 2021, Volume: 53, Issue:1

    Topics: Colitis; Fatigue Syndrome, Chronic; Humans; Inflammatory Bowel Diseases; Pilot Projects; Thiamine

2021

Other Studies

6 other studies available for thiamine and Bowel Diseases, Inflammatory

ArticleYear
Gut-Brain Axis: Insights from Hippocampal Neurogenesis and Brain Tumor Development in a Mouse Model of Experimental Colitis Induced by Dextran Sodium Sulfate.
    International journal of molecular sciences, 2022, Sep-29, Volume: 23, Issue:19

    Topics: Amino Acids; Animals; Brain Neoplasms; Brain-Gut Axis; Carcinogenesis; Colitis; Colon; Cytokines; De

2022
Editorial: a pipe dream fulfilled? A therapeutic option for fatigue in IBD. Authors' reply.
    Alimentary pharmacology & therapeutics, 2021, Volume: 53, Issue:2

    Topics: Colitis; Fatigue; Fatigue Syndrome, Chronic; Humans; Inflammatory Bowel Diseases; Thiamine

2021
Editorial: a pipe dream fulfilled? A therapeutic option for fatigue in IBD.
    Alimentary pharmacology & therapeutics, 2021, Volume: 53, Issue:2

    Topics: Colitis; Fatigue; Fatigue Syndrome, Chronic; Humans; Inflammatory Bowel Diseases; Thiamine

2021
Letter: future studies of high-dose thiamine should consider whether its effects on fatigue are related to the inhibition of carbonic anhydrase isoenzymes. Authors' reply.
    Alimentary pharmacology & therapeutics, 2021, Volume: 53, Issue:7

    Topics: Carbonic Anhydrases; Fatigue Syndrome, Chronic; Humans; Inflammatory Bowel Diseases; Isoenzymes; Thi

2021
Letter: future studies of high-dose thiamine should consider whether its effects on fatigue are related to the inhibition of carbonic anhydrase isoenzymes.
    Alimentary pharmacology & therapeutics, 2021, Volume: 53, Issue:7

    Topics: Carbonic Anhydrases; Fatigue Syndrome, Chronic; Humans; Inflammatory Bowel Diseases; Isoenzymes; Thi

2021
Thiamine and fatigue in inflammatory bowel diseases: an open-label pilot study.
    Journal of alternative and complementary medicine (New York, N.Y.), 2013, Volume: 19, Issue:8

    Topics: Adult; Fatigue; Female; Humans; Inflammatory Bowel Diseases; Male; Middle Aged; Pilot Projects; Thia

2013