thiamine and Ataxia
thiamine has been researched along with Ataxia in 38 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Some observations indicate that all symptoms of FRDA ataxia could be the manifestation of a thiamine deficiency because of enzymatic abnormalities." | 7.79 | High-dose thiamine improves the symptoms of Friedreich's ataxia. ( Costantini, A; D'Agostino, S; Giorgi, R; Pala, MI, 2013) |
| "Thiamine (vitamin B(1)) is an essential component of a number of metabolic pathways and thiamine deficiency results in a progressive encephalopathy in both humans and animals." | 7.76 | Thiamine deficiency in a cat: resolution of MRI abnormalities following thiamine supplementation. ( Cherubini, GB; Jakovljevic, S; Palus, V; Penderis, J, 2010) |
| " On the third day of thiamine replacement, neurologic signs improved dramatically In addition to our case, we review 29 previously reported cases of Wernicke's encephalopathy associated with hyperemesis gravidarum, and emphasize the importance of thiamine supplementation to women with prolonged vomiting in pregnancy especially if they are given intravenous or parenteral nutrition." | 4.81 | Wernicke's encephalopathy due to hyperemesis gravidarum: an under-recognised condition. ( Mutluer, N; Togay-Işikay, C; Yiğit, A, 2001) |
| "Wernicke encephalopathy (WE) is a neuropsychiatric disorder caused by thiamine deficiency." | 3.88 | Wernicke encephalopathy without delirium in patients with cancer. ( Akechi, T; Furuya, D; Ikebuchi, K; Ishida, M; Onishi, H; Taji, Y; Takahashi, T; Tanahashi, I, 2018) |
| "Wernicke's encephalopathy is an acute, potentially life-threatening, neurological syndrome resulting from thiamine deficiency." | 3.80 | [Wernicke's encephalopathy induced by the use of diet pills and unbalanced diet]. ( Aradi, G; Arányi, Z; Bereczki, D; Tóth, A; Várallyay, G; Vastagh, I, 2014) |
| " Some observations indicate that all symptoms of FRDA ataxia could be the manifestation of a thiamine deficiency because of enzymatic abnormalities." | 3.79 | High-dose thiamine improves the symptoms of Friedreich's ataxia. ( Costantini, A; D'Agostino, S; Giorgi, R; Pala, MI, 2013) |
| "Thiamine (vitamin B(1)) is an essential component of a number of metabolic pathways and thiamine deficiency results in a progressive encephalopathy in both humans and animals." | 3.76 | Thiamine deficiency in a cat: resolution of MRI abnormalities following thiamine supplementation. ( Cherubini, GB; Jakovljevic, S; Palus, V; Penderis, J, 2010) |
| "Wernicke's encephalopathy is a neurologic disorder due to a nutritional deficiency of thiamine, characterized by ocular palsies, ataxia, and altered mental activity." | 3.70 | A common cause of altered mental status occurring at an uncommon age. ( Decker, MJ; Isaacman, DJ, 2000) |
| "Wernicke-Korsakoff syndrome (WKS) is a neurological disorder typically found in alcohol use disorder." | 2.72 | Wernicke-Korsakoff syndrome despite no alcohol abuse: A summary of systematic reports. ( Oey, MJ; Oudman, E; Postma, A; van Dam, M; Wijnia, JW, 2021) |
| "Wernicke-Korsakoff syndrome (WKS) is most often seen in people who are alcohol dependent." | 2.70 | Thiamin treatment and working memory function of alcohol-dependent people: preliminary findings. ( Ambrose, ML; Bowden, SC; Whelan, G, 2001) |
| "Treatment with thiamine while awaiting the outcome of diagnostic tests may be a good choice." | 1.72 | Case report of two affected siblings in a family with thiamine metabolism dysfunction syndrome 5: a rare, but treatable neurodegenerative disease. ( Chen, H; Chen, Y; Huang, Z; Li, X; Sun, X; Xie, J; Yi, Z; Yu, X; Zhong, J, 2022) |
| "Wernicke encephalopathy is a neurological emergency that should be treated immediately with high-dose intravenous thiamine for a week, if suspected." | 1.62 | [Orientation disorder, ophthalmoplegia and ataxia in a 48-year-old male]. ( Dams, L; Krämer, M, 2021) |
| "Seasonal ataxia is a clinical syndrome of acute cerebellar ataxia which follows ingestion of roasted larvae of Anaphe venata Butler, an alternative protein source consumed in western Nigeria." | 1.40 | Seasonal ataxia: A case report of a disappearing disease. ( Ayoade Moyo, A; Michael Bimbo, F; Morenikeji Adeyoyin, K; Oluwatoyin, G; Valentine Nnaemeka, A; Victor Oladeji, A, 2014) |
| "A 33-year-old woman with Wernicke's encephalopathy (WE) due to poor oral intake after allogeneic stem cell transplantation for acute myeloid leukemia showed a sequential development of bilateral gaze-evoked nystagmus (GEN), rightward gaze palsy, and upbeat nystagmus." | 1.38 | Evolution of abnormal eye movements in Wernicke's encephalopathy: correlation with serial MRI findings. ( Kim, JS; Kim, K; Lee, YB; Park, HM; Park, KH; Shin, DH; Shin, DJ, 2012) |
| "A classic presentation of Wernicke's encephalopathy is reported." | 1.29 | Reversible neurological deficits in a chronic alcohol abuser: a case report of Wernicke's encephalopathy. ( Brady, W; DeBehnke, D; Guido, ME, 1994) |
| "Neurologic signs (opisthotonus and ataxia) appeared in the course of thiamin deficiency or did not appear at all during the entire athiaminosis period." | 1.26 | Liver and brain thiamin depletion and neurologic signs in pigeon athiaminosis. ( Cappelli, V; Cariani, T; Ferrari, G, 1976) |
| "Treatment with thiamine derivatives may have a beneficial effect on the clinical course." | 1.25 | [Subacute necrotizing encephalomyelopathy (Leigh's disease) (author's transl)]. ( Förster, C; Murken, JD, 1975) |
Research
Studies (38)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (36.84) | 18.7374 |
| 1990's | 4 (10.53) | 18.2507 |
| 2000's | 7 (18.42) | 29.6817 |
| 2010's | 8 (21.05) | 24.3611 |
| 2020's | 5 (13.16) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Ding, LM | 1 |
| Deng, LS | 1 |
| Qian, JJ | 1 |
| Liu, G | 1 |
| Zhou, L | 1 |
| Zheng, SS | 1 |
| Li, X | 1 |
| Huang, Z | 1 |
| Chen, Y | 1 |
| Sun, X | 1 |
| Yi, Z | 1 |
| Xie, J | 1 |
| Yu, X | 1 |
| Chen, H | 1 |
| Zhong, J | 1 |
| Zhu, B | 1 |
| Wu, J | 1 |
| Chen, G | 1 |
| Chen, L | 1 |
| Yao, Y | 1 |
| Oudman, E | 1 |
| Wijnia, JW | 1 |
| Oey, MJ | 1 |
| van Dam, M | 1 |
| Postma, A | 1 |
| Dams, L | 1 |
| Krämer, M | 1 |
| Onishi, H | 1 |
| Ishida, M | 1 |
| Tanahashi, I | 1 |
| Takahashi, T | 1 |
| Taji, Y | 1 |
| Ikebuchi, K | 1 |
| Furuya, D | 1 |
| Akechi, T | 1 |
| Costantini, A | 1 |
| Giorgi, R | 1 |
| D'Agostino, S | 1 |
| Pala, MI | 1 |
| Tóth, A | 1 |
| Aradi, G | 1 |
| Várallyay, G | 1 |
| Arányi, Z | 1 |
| Bereczki, D | 1 |
| Vastagh, I | 1 |
| Gliebus, G | 1 |
| Faerber, EN | 1 |
| Valencia, I | 1 |
| Khurana, DS | 1 |
| Singh, SB | 1 |
| Legido, A | 1 |
| Ayoade Moyo, A | 1 |
| Michael Bimbo, F | 1 |
| Morenikeji Adeyoyin, K | 1 |
| Valentine Nnaemeka, A | 1 |
| Oluwatoyin, G | 1 |
| Victor Oladeji, A | 1 |
| MacDonald, RJ | 1 |
| Stanich, PP | 1 |
| Monrad, PA | 1 |
| Mateen, FJ | 1 |
| Palus, V | 1 |
| Penderis, J | 1 |
| Jakovljevic, S | 1 |
| Cherubini, GB | 1 |
| Bamitale, KD | 1 |
| Akanmu, MA | 1 |
| Ukponmwan, OE | 1 |
| Kim, K | 1 |
| Shin, DH | 1 |
| Lee, YB | 1 |
| Park, KH | 1 |
| Park, HM | 1 |
| Shin, DJ | 1 |
| Kim, JS | 1 |
| LATHAM, MC | 1 |
| EBRAHIM, GJ | 1 |
| HADDOCK, DR | 1 |
| Giglioli, L | 1 |
| Salani, B | 1 |
| Mannucci, M | 1 |
| Kinsella, LJ | 1 |
| Adamolekun, B | 1 |
| Adamolekun, WE | 1 |
| Sonibare, AD | 1 |
| Sofowora, G | 1 |
| Guido, ME | 1 |
| Brady, W | 1 |
| DeBehnke, D | 1 |
| Sainte-Foie, S | 1 |
| Bourhis, V | 1 |
| Joly, F | 1 |
| Petit-Bon, J | 1 |
| Decker, MJ | 1 |
| Isaacman, DJ | 1 |
| Nishimune, T | 1 |
| Watanabe, Y | 1 |
| Okazaki, H | 1 |
| Akai, H | 1 |
| Ambrose, ML | 1 |
| Bowden, SC | 1 |
| Whelan, G | 1 |
| Togay-Işikay, C | 1 |
| Yiğit, A | 1 |
| Mutluer, N | 1 |
| Cymbaluk, NF | 1 |
| Fretz, PB | 1 |
| Loew, FM | 1 |
| Ferrari, G | 1 |
| Cappelli, V | 1 |
| Cariani, T | 1 |
| Förster, C | 1 |
| Murken, JD | 1 |
| Morgan, KL | 1 |
| Reuler, JB | 1 |
| Girard, DE | 1 |
| Cooney, TG | 1 |
| Osuntokun, BO | 1 |
| Aladetoyinbo, A | 1 |
| Bademosi, O | 1 |
| Schiffter, R | 1 |
| Nagi, NA | 1 |
| Yassin, AK | 1 |
| Blass, JP | 2 |
| Avigan, J | 1 |
| Uhlendorf, BW | 1 |
| Schmidt, D | 1 |
| Kark, AP | 1 |
| Engel, WK | 1 |
| Bitter, RA | 1 |
| Gubler, CJ | 2 |
| Heninger, RW | 1 |
| Cheney, DL | 1 |
| Jaussi, AW | 1 |
Reviews
3 reviews available for thiamine and Ataxia
| Article | Year |
|---|---|
Wernicke-Korsakoff syndrome despite no alcohol abuse: A summary of systematic reports.
Topics: Adult; Alcoholism; Ataxia; Child; Female; Humans; Korsakoff Syndrome; Pregnancy; Thiamine; Thiamine | 2021 |
Wernicke's encephalopathy due to hyperemesis gravidarum: an under-recognised condition.
Topics: Adult; Ataxia; Diagnosis, Differential; Female; Humans; Hyperemesis Gravidarum; Infant, Newborn; Inj | 2001 |
Current concepts. Wernicke's encephalopathy.
Topics: Alcoholism; Ataxia; Brain; Coma; Confusion; Humans; Hypotension; Hypothermia; Nutrition Disorders; O | 1985 |
Trials
2 trials available for thiamine and Ataxia
| Article | Year |
|---|---|
A double-blind, placebo-controlled study of the efficacy of thiamine hydrochloride in a seasonal ataxia in Nigerians.
Topics: Adult; Analysis of Variance; Ataxia; Double-Blind Method; Female; Humans; Male; Middle Aged; Nigeria | 1994 |
Thiamin treatment and working memory function of alcohol-dependent people: preliminary findings.
Topics: Adult; Alcoholism; Analysis of Variance; Ataxia; Double-Blind Method; Humans; Korsakoff Syndrome; Me | 2001 |
Other Studies
33 other studies available for thiamine and Ataxia
| Article | Year |
|---|---|
Clinical analysis of Wernicke encephalopathy after liver transplantation.
Topics: Ataxia; Humans; Liver Transplantation; Magnetic Resonance Imaging; Retrospective Studies; Thiamine; | 2023 |
Case report of two affected siblings in a family with thiamine metabolism dysfunction syndrome 5: a rare, but treatable neurodegenerative disease.
Topics: Ataxia; Brain Diseases; Humans; Male; Muscle Hypotonia; Mutation; Neurodegenerative Diseases; Siblin | 2022 |
Whole Exome Sequencing Identifies a Novel Mutation of TPK1 in a Chinese Family with Recurrent Ataxia.
Topics: Ataxia; Binding Sites; Brain Diseases; Child, Preschool; Exome Sequencing; Genetic Testing; Humans; | 2020 |
[Orientation disorder, ophthalmoplegia and ataxia in a 48-year-old male].
Topics: Ataxia; Humans; Male; Middle Aged; Ophthalmoplegia; Thiamine; Wernicke Encephalopathy | 2021 |
Wernicke encephalopathy without delirium in patients with cancer.
Topics: Ataxia; Delirium; Female; Humans; Middle Aged; Neoplasms; Thiamine; Thiamine Deficiency; Wernicke En | 2018 |
High-dose thiamine improves the symptoms of Friedreich's ataxia.
Topics: Adult; Ataxia; Female; Friedreich Ataxia; Humans; Male; Thiamine; Thiamine Deficiency; Vitamin B Com | 2013 |
[Wernicke's encephalopathy induced by the use of diet pills and unbalanced diet].
Topics: Alcoholism; Ataxia; Diet, Reducing; Feeding Behavior; Female; Humans; Oculomotor Nerve Diseases; Thi | 2014 |
Ataxia, ophthalmoplegia, and impairment of consciousness in a 19-month-old American boy.
Topics: Ataxia; Consciousness Disorders; Diagnosis, Differential; Humans; Infant; Magnetic Resonance Imaging | 2014 |
Seasonal ataxia: A case report of a disappearing disease.
Topics: Adult; Animals; Ataxia; Bombyx; Diet; Female; Humans; Larva; Nigeria; Seasons; Thiamine; Treatment O | 2014 |
Teaching Video NeuroImages: Wernicke encephalopathy without mental status changes.
Topics: Adult; Ataxia; Brain; Diagnosis, Differential; Humans; Magnetic Resonance Imaging; Male; Neurologic | 2009 |
Thiamine deficiency in a cat: resolution of MRI abnormalities following thiamine supplementation.
Topics: Animals; Ataxia; Brain; Cat Diseases; Cats; Dietary Supplements; Female; Magnetic Resonance Imaging; | 2010 |
Neuropharmacological profile of aqueous extract of Anaphe venata larva (Notondotidae) in rats.
Topics: Amphetamine; Animals; Ataxia; Behavior, Animal; Dose-Response Relationship, Drug; Flumazenil; Groomi | 2011 |
Evolution of abnormal eye movements in Wernicke's encephalopathy: correlation with serial MRI findings.
Topics: Adult; Ataxia; Disease Progression; Eye Movements; Female; Humans; Leukemia, Myeloid, Acute; Magneti | 2012 |
NUTRITIONAL AETIOLOGY OF A NEUROPATHY FOUND IN TANGANYIKA.
Topics: Ataxia; Diet; Diet Therapy; Humans; Niacin; Nicotinic Acids; Riboflavin; Tanzania; Thiamine; Vitamin | 1964 |
POLYNEUROPATHY OF PROBABLE NUTRITIONAL ORIGIN IN DAR-ES-SALAAM, TANGANYIKA.
Topics: Ataxia; Deficiency Diseases; Humans; Muscular Diseases; Niacin; Nicotinic Acids; Nutrition Surveys; | 1964 |
Case report: mental confusion, diplopia, and inability to stand in an 82-year-old-man.
Topics: Aged; Aged, 80 and over; Ataxia; Confusion; Diagnosis, Differential; Diplopia; Humans; Male; Nutriti | 2004 |
Bright red nuclei.
Topics: Ataxia; Brain Neoplasms; Diagnosis, Differential; Diplopia; Dysarthria; Female; Humans; Korsakoff Sy | 2004 |
Reversible neurological deficits in a chronic alcohol abuser: a case report of Wernicke's encephalopathy.
Topics: Adult; Alcoholism; Ataxia; Confusion; Diagnosis, Differential; Emergency Service, Hospital; Female; | 1994 |
[Neuromyelopathy in the population of Noir-marron of Saint-Laurent du Maroni in French Guiana].
Topics: Adolescent; Adult; Ataxia; Cardiac Output, Low; Cerebellar Ataxia; Delirium; Dermatitis; Diet; Ethni | 1997 |
A common cause of altered mental status occurring at an uncommon age.
Topics: Ataxia; Child; Female; Food; Humans; Mental Disorders; Starvation; Thiamine; Thiamine Deficiency; We | 2000 |
Thiamin is decomposed due to Anaphe spp. entomophagy in seasonal ataxia patients in Nigeria.
Topics: Animals; Ataxia; Bombyx; Chromatography, Gel; Diet; Humans; Hydrolases; Nigeria; Seasons; Substrate | 2000 |
Amprolium-induced thiamine deficiency in horses: clinical features.
Topics: Amprolium; Animals; Ataxia; Blood Glucose; Diarrhea; Horse Diseases; Horses; Lactates; Male; Phospho | 1978 |
Liver and brain thiamin depletion and neurologic signs in pigeon athiaminosis.
Topics: Animals; Ataxia; Brain; Columbidae; Liver; Male; Pyruvates; Spasm; Thiamine; Thiamine Deficiency | 1976 |
[Subacute necrotizing encephalomyelopathy (Leigh's disease) (author's transl)].
Topics: Age Factors; Ataxia; Athetosis; Autopsy; Brain Stem; Child; Child, Preschool; Chorea; Encephalomalac | 1975 |
Ataxia and head tremor in an alpaca (Lama pacos)
Topics: Amoxicillin; Animals; Ataxia; Camelids, New World; Copper; Diagnosis, Differential; Drug Therapy, Co | 1992 |
Vitamin B nutrition in the Nigerian tropical ataxic neuropathy.
Topics: Adult; Ataxia; Cyanides; Diet; Female; Humans; Male; Manihot; Middle Aged; Nigeria; Nutritional Phys | 1985 |
[Bilateral horizontal gaze paralyses. Clinical analysis of three cases].
Topics: Abducens Nerve; Adult; Alcohol Amnestic Disorder; Ataxia; Diplopia; Female; Humans; Male; Middle Age | 1971 |
Organic mercury poisoning in children.
Topics: Ataxia; Child; Diet; Dimercaprol; Edetic Acid; Female; Fungicides, Industrial; Hemoglobins; Humans; | 1974 |
A defect in pyruvate decarboxylase in a child with an intermittent movement disorder.
Topics: Alanine; Ataxia; Carbon Isotopes; Carboxy-Lyases; Child; Female; Fibroblasts; Humans; Lactates; Leuk | 1970 |
[Significance of ocular symptoms in the diagnosis of Wernicke's encephalopathy].
Topics: Abducens Nerve; Aged; Alcohol Amnestic Disorder; Alcoholism; Ataxia; Diagnosis, Differential; Eye Ma | 1972 |
Clinical studies of a patient with pyruvate decarboxylase deficiency.
Topics: Amino Acids; Ataxia; Carboxy-Lyases; Child; Dexamethasone; Electrocardiography; Electroencephalograp | 1971 |
Effects of forced-feeding on blood levels of pyruvate, glucocorticoids and glucose and on adrenal weight in thiamine-deprived and thiamine antagonist-treated rats.
Topics: Adrenal Glands; Animals; Ataxia; Blood Glucose; Corticosterone; Diet; Feeding and Eating Disorders; | 1969 |
Production of acetylcholine in rat brain following thiamine deprivation and treatment with thiamine antagonists.
Topics: Acetylcholine; Animals; Ataxia; Brain; Carbon Isotopes; Centrifugation; Chromatography; Diet; Male; | 1969 |