thiamine has been researched along with Amyotrophic Lateral Sclerosis in 7 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigated the toxic effects of excess extracellular copper on motor neuronal cells expressing human mutant SOD1 (G93A), and evaluated the neuroprotective effects of energy metabolism intermediates or cofactors." | 1.33 | Pyruvate protects motor neurons expressing mutant superoxide dismutase 1 against copper toxicity. ( Kim, HJ; Kim, JM; Kim, M; Lee, KW; Park, JH; Sung, JJ, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Probert, F | 3 |
| Gorlova, A | 3 |
| Deikin, A | 3 |
| Bettendorff, L | 3 |
| Veniaminova, E | 3 |
| Nedorubov, A | 3 |
| Chaprov, KD | 3 |
| Ivanova, TA | 3 |
| Anthony, DC | 3 |
| Strekalova, T | 3 |
| KAWAKITA, Y | 1 |
| IGAWA, G | 1 |
| NAGAHAMA, S | 1 |
| HAMANAKA, T | 1 |
| TSURUMARU, Y | 1 |
| KURAUCHI, K | 1 |
| MORI, H | 1 |
| Kim, HJ | 1 |
| Kim, JM | 1 |
| Park, JH | 1 |
| Sung, JJ | 1 |
| Kim, M | 1 |
| Lee, KW | 1 |
| Poloni, M | 2 |
| Patrini, C | 2 |
| Rocchelli, B | 1 |
| Rindi, G | 1 |
| Rowland, LP | 1 |
| Miyaji, K | 1 |
| Mazzarello, P | 1 |
| Pinelli, P | 1 |
1 review available for thiamine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Controversies about amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Chelation Therapy; Humans; Peripheral Nerves; Thiamine; Venoms; Vitam | 1996 |
6 other studies available for thiamine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
In FUS[1-359]-tg mice O,S-dibenzoyl thiamine reduces muscle atrophy, decreases glycogen synthase kinase 3 beta, and normalizes the metabolome.
Topics: Amyotrophic Lateral Sclerosis; Animals; Glycogen Synthase Kinase 3 beta; Metabolome; Mice; Mice, Tra | 2022 |
In FUS[1-359]-tg mice O,S-dibenzoyl thiamine reduces muscle atrophy, decreases glycogen synthase kinase 3 beta, and normalizes the metabolome.
Topics: Amyotrophic Lateral Sclerosis; Animals; Glycogen Synthase Kinase 3 beta; Metabolome; Mice; Mice, Tra | 2022 |
In FUS[1-359]-tg mice O,S-dibenzoyl thiamine reduces muscle atrophy, decreases glycogen synthase kinase 3 beta, and normalizes the metabolome.
Topics: Amyotrophic Lateral Sclerosis; Animals; Glycogen Synthase Kinase 3 beta; Metabolome; Mice; Mice, Tra | 2022 |
In FUS[1-359]-tg mice O,S-dibenzoyl thiamine reduces muscle atrophy, decreases glycogen synthase kinase 3 beta, and normalizes the metabolome.
Topics: Amyotrophic Lateral Sclerosis; Animals; Glycogen Synthase Kinase 3 beta; Metabolome; Mice; Mice, Tra | 2022 |
In FUS[1-359]-tg mice O,S-dibenzoyl thiamine reduces muscle atrophy, decreases glycogen synthase kinase 3 beta, and normalizes the metabolome.
Topics: Amyotrophic Lateral Sclerosis; Animals; Glycogen Synthase Kinase 3 beta; Metabolome; Mice; Mice, Tra | 2022 |
In FUS[1-359]-tg mice O,S-dibenzoyl thiamine reduces muscle atrophy, decreases glycogen synthase kinase 3 beta, and normalizes the metabolome.
Topics: Amyotrophic Lateral Sclerosis; Animals; Glycogen Synthase Kinase 3 beta; Metabolome; Mice; Mice, Tra | 2022 |
In FUS[1-359]-tg mice O,S-dibenzoyl thiamine reduces muscle atrophy, decreases glycogen synthase kinase 3 beta, and normalizes the metabolome.
Topics: Amyotrophic Lateral Sclerosis; Animals; Glycogen Synthase Kinase 3 beta; Metabolome; Mice; Mice, Tra | 2022 |
In FUS[1-359]-tg mice O,S-dibenzoyl thiamine reduces muscle atrophy, decreases glycogen synthase kinase 3 beta, and normalizes the metabolome.
Topics: Amyotrophic Lateral Sclerosis; Animals; Glycogen Synthase Kinase 3 beta; Metabolome; Mice; Mice, Tra | 2022 |
In FUS[1-359]-tg mice O,S-dibenzoyl thiamine reduces muscle atrophy, decreases glycogen synthase kinase 3 beta, and normalizes the metabolome.
Topics: Amyotrophic Lateral Sclerosis; Animals; Glycogen Synthase Kinase 3 beta; Metabolome; Mice; Mice, Tra | 2022 |
[A CLINICAL TRIAL OF TEA-5D ON THE NEUROLOGICAL AND PSYCHIATRIC DISORDERS].
Topics: Amyotrophic Lateral Sclerosis; Catatonia; Erectile Dysfunction; Fatigue; Hemiplegia; Humans; Male; M | 1964 |
Pyruvate protects motor neurons expressing mutant superoxide dismutase 1 against copper toxicity.
Topics: Amyotrophic Lateral Sclerosis; Cell Death; Cell Line, Tumor; Copper; Energy Metabolism; Free Radical | 2005 |
Thiamin monophosphate in the CSF of patients with amyotrophic lateral sclerosis.
Topics: Adult; Aged; Alcoholism; Amyotrophic Lateral Sclerosis; Blood Proteins; Female; Humans; Male; Middle | 1982 |
Thiamine metabolism in patients with nervous diseases.
Topics: Adult; Amyotrophic Lateral Sclerosis; Central Nervous System Diseases; Cerebrovascular Disorders; Hu | 1976 |
Inversion of T/TMP ratio in ALS: a specific finding?
Topics: Adult; Amyotrophic Lateral Sclerosis; Humans; Myotonic Dystrophy; Peripheral Nervous System Diseases | 1986 |