thiamine has been researched along with Alcohol Withdrawal Associated Autonomic Hyperactivity in 16 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The patients with visual hallucinations, however, showed lower thiamine absorption than patients without such symptoms, whereas no dependence of autonomic symptoms on vitamin B1 absorption was seen." | 3.69 | Thiamine absorption in alcoholic delirium patients. ( Holzbach, E, 1996) |
| " Dosage should be individualized, based on withdrawal severity measured by withdrawal scales, comorbid illness, and history of withdrawal seizures." | 2.40 | Pharmacological management of alcohol withdrawal. A meta-analysis and evidence-based practice guideline. American Society of Addiction Medicine Working Group on Pharmacological Management of Alcohol Withdrawal. ( Mayo-Smith, MF, 1997) |
| "Three were alcohol abusers, and one had prolonged vomiting and anorexia." | 1.29 | Thiamin and thiamin phosphate ester deficiency assessed by high performance liquid chromatography in four clinical cases of Wernicke encephalopathy. ( Bell, H; Bøhmer, T; Tallaksen, CM, 1993) |
| "The magnesium deficiency is discussed for longstanding malnutrition in both groups, the vitamin B-1 deficiency for an unusual high intake of alcohol before delirium tremens started." | 1.26 | The significance of the serum levels of vitamin B-1 and magnesium in delirium tremens and alcoholism. ( Hoes, MJ, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (37.50) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schuckit, MA | 1 |
| Talbot, PA | 1 |
| Demirkol, A | 1 |
| Conigrave, K | 1 |
| Haber, P | 1 |
| Hensel, M | 1 |
| Kox, WJ | 1 |
| BOECKER, F | 1 |
| SATTES, H | 1 |
| Okudaira, K | 1 |
| Sakata, S | 1 |
| Nakamura, J | 1 |
| Lewis, DC | 1 |
| Femino, J | 1 |
| Holloway, HC | 1 |
| Hales, RE | 1 |
| Watanabe, HK | 1 |
| Everett, G | 1 |
| Tallaksen, CM | 1 |
| Bell, H | 1 |
| Bøhmer, T | 1 |
| Holzbach, E | 1 |
| Mayo-Smith, MF | 1 |
| Hoes, MJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acamprosate for Central Nervous System Hyperexcitability and Neuroadaptation in Alcohol Withdrawal[NCT00106106] | Phase 2 | 56 participants (Actual) | Interventional | 2005-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The ratio of glutamate to creatine was determined using magnetic resonance spectroscopy (MRS), a technique that complements magnetic resonance imaging (MRI). MRS is used to determine the concentration of brain metabolites, such as glutamate, in brain tissue. MRS utilizes a magnetic field to look at magnetic nuclei, which absorb and re-emit electromagnetic energy in the presence of the magnetic field. By looking at the peaks in the resultant spectra the structure and concentration of metabolites can be determined. (NCT00106106)
Timeframe: Day 25
| Intervention | Ratio of glutamate to creatine (Mean) |
|---|---|
| Placebo | 1.350375 |
| Acamprosate | 1.166667 |
The ratio of glutamate to creatine was determined using magnetic resonance spectroscopy (MRS), a technique that complements magnetic resonance imaging (MRI). MRS is used to determine the concentration of brain metabolites, such as glutamate, in brain tissue. MRS utilizes a magnetic field to look at magnetic nuclei, which absorb and re-emit electromagnetic energy in the presence of the magnetic field. By looking at the peaks in the resultant spectra the structure and concentration of metabolites can be determined. (NCT00106106)
Timeframe: Day 4
| Intervention | Ratio of glutamate to creatine (Mean) |
|---|---|
| Placebo | 1.256772 |
| Acamprosate | 1.294178 |
4 reviews available for thiamine and Alcohol Withdrawal Associated Autonomic Hyperactivity
| Article | Year |
|---|---|
Recognition and management of withdrawal delirium (delirium tremens).
Topics: Alcohol Withdrawal Delirium; Benzodiazepines; Central Nervous System Depressants; Diazepam; Disease | 2014 |
[Late withdrawal syndrome].
Topics: Alcohol Withdrawal Delirium; Benzodiazepines; Diagnosis, Differential; Electrolytes; Ethanol; Fluid | 2003 |
[Delirium tremens].
Topics: Alcohol Withdrawal Delirium; Alcoholism; Antidepressive Agents; Antipsychotic Agents; Benzodiazepine | 2003 |
Pharmacological management of alcohol withdrawal. A meta-analysis and evidence-based practice guideline. American Society of Addiction Medicine Working Group on Pharmacological Management of Alcohol Withdrawal.
Topics: Adrenergic beta-Antagonists; Alcohol Withdrawal Delirium; Antipsychotic Agents; Benzodiazepines; Car | 1997 |
12 other studies available for thiamine and Alcohol Withdrawal Associated Autonomic Hyperactivity
| Article | Year |
|---|---|
Timing of efficacy of thiamine in Wernicke's disease in alcoholics at risk.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholics; Alcoholism; Health Surveys; Humans; Middle Aged; Pri | 2011 |
Problem drinking--management in general practice.
Topics: Alcohol Withdrawal Delirium; Alcohol-Related Disorders; Alcoholism; Counseling; General Practice; Hu | 2011 |
[Can alcoholic withdrawal delirium be prevented?].
Topics: Alcohol Withdrawal Delirium; Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; | 2003 |
[DELIRIUM TREMENS: TODAY CONTROLLABLE].
Topics: Alcohol Withdrawal Delirium; Cephapirin; Drug Therapy; Humans; Mental Disorders; Psychoses, Alcoholi | 1965 |
[THE TREATMENT OF DELIRIUM TREMENS WITH DISTRANEURIN].
Topics: Alcohol Withdrawal Delirium; Chlormethiazole; Drug Therapy; Humans; Mental Disorders; Psychoses, Alc | 1964 |
Alcohol withdrawal syndrome: how to predict, prevent, diagnose and treat it.
Topics: Adrenergic beta-Antagonists; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Ambulatory Ca | 2007 |
Management of alcohol withdrawal.
Topics: Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Benzodiazepines; Humans; Psychoses, Alcoholic; Sei | 1982 |
Recognition and treatment of acute alcohol withdrawal syndromes.
Topics: Acute Disease; Alcohol Withdrawal Delirium; Alcoholism; Benzodiazepines; Chloral Hydrate; Ethanol; F | 1984 |
Alcohol withdrawal syndrome: prevention and treatment.
Topics: Administration, Oral; Alcohol Drinking; Alcohol Withdrawal Delirium; Benzodiazepines; Ethanol; Human | 1981 |
Thiamin and thiamin phosphate ester deficiency assessed by high performance liquid chromatography in four clinical cases of Wernicke encephalopathy.
Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Blood-Brain Barrier; Brain; Female; Humans; Ma | 1993 |
Thiamine absorption in alcoholic delirium patients.
Topics: Adult; Alcohol Withdrawal Delirium; Hallucinations; Humans; Intestinal Absorption; Male; Middle Aged | 1996 |
The significance of the serum levels of vitamin B-1 and magnesium in delirium tremens and alcoholism.
Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Humans; Magnesium; Magnesium Deficiency; Middl | 1979 |