thiamine has been researched along with Alcohol Abuse in 361 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Furthermore, we suggest thiamine, which is frequently depleted in AUD, to be a key modulator in this process: Thiamine deficiency impairs the integrity of the blood-brain barrier, thereby enabling iron to pass through and accumulate in the brain." | 9.05 | Does thiamine protect the brain from iron overload and alcohol-related dementia? ( Hametner, S; König, D; Listabarth, S; Vyssoki, B, 2020) |
| "Thiamine deficiency has been specifically linked to the development of Wernicke-Korsakoff syndrome (WK)--a degenerative brain disorder that is typically associated with alcoholic drinking." | 8.83 | A theoretical argument for inherited thiamine insensitivity as one possible biological cause of familial alcoholism. ( Manzardo, AM; Penick, EC, 2006) |
| "Acute thiamine deficiency can occur in patients with or without history of alcohol abuse and can lead to life-threatening complications." | 8.12 | Clinical diagnosis, outcomes and treatment of thiamine deficiency in a tertiary hospital. ( Balanant, NA; Carette, C; Czernichow, S; Flamarion, E; Jannot, AS; Lucas-Martini, L; Messager, D; Mifsud, F; Poghosyan, T; Rives-Lange, C; Védie, B, 2022) |
| "To describe thiamine supplementation incidence in patients with AUD and various critical illnesses (alcohol withdrawal, septic shock, traumatic brain injury [TBI], and diabetic ketoacidosis [DKA]) in the United States." | 8.12 | Thiamine Supplementation in Patients With Alcohol Use Disorder Presenting With Acute Critical Illness : A Nationwide Retrospective Observational Study. ( Balaji, L; Berg, KM; Donnino, MW; Grossestreuer, AV; Holmberg, MJ; Issa, MS; Kronen, R; Moskowitz, A; Patel, PV; Pawar, RD; Thompson, G, 2022) |
| "To assess relationships of thiamine usage to outcomes of patients hospitalized with alcohol use disorder and pneumonia." | 8.12 | Early treatment with thiamine and mortality among patients with alcohol use disorder who are hospitalized for pneumonia. ( Baron, SW; Deshpande, A; Imrey, PB; Rothberg, MB; Southern, WN; Yu, PC, 2022) |
| "The results indicated that thiamine therapy could be a protective factor for dementia development in patients with alcohol use disorder." | 7.91 | Thiamine for preventing dementia development among patients with alcohol use disorder: A nationwide population-based cohort study. ( Chang, YH; Chen, YY; Chou, WP; Ko, CH; Lin, HC, 2019) |
| "The effects of chronic EtOH consumption, associated or not with thiamine deficiency (TD), on cognitive impairment, oxidative damage, and β-amyloid (Aβ) peptide accumulation in the brain were investigated in male C57BL/6 mice." | 7.85 | Comparative effects of EtOH consumption and thiamine deficiency on cognitive impairment, oxidative damage, and β-amyloid peptide overproduction in the brain. ( Gao, YQ; Gong, YS; Guo, J; Hou, FL; Hu, K; Liang, CY; Song, FL; Yang, LQ, 2017) |
| ""Shoshin beriberi", which is a fulminant form of cardiovascular beriberi accompanied by hemodynamic deterioration with high cardiac output and decreased systemic blood pressure, caused by thiamine deficiency due to alcoholic abuse or malnutrition, is often difficult to address because of its rarity and non-specific symptoms." | 7.81 | Shoshin Beriberi With Low Cardiac Output and Hemodynamic Deterioration Treated Dramatically by Thiamine Administration. ( Imamura, T; Kinugawa, K, 2015) |
| " Given the low risk and cost of BAL testing and thiamine prophylaxis and the high cost of delirium, standard protocols for prophylaxis are essential." | 7.80 | Prevention of delirium in trauma patients: are we giving thiamine prophylaxis a fair chance? ( Ball, CG; Blackmore, C; Kirkpatrick, AW; Niven, D; Ouellet, JF, 2014) |
| " Chronic alcoholism is usually associated with thiamine deficiency (TD) which is known to induce selective neurodegeneration in the brain." | 7.75 | Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase. ( Fan, Z; Ke, ZJ; Luo, J; Wang, X, 2009) |
| "Wernicke's encephalopathy (WE) is characterized by lesions in thalamus, hypothalamus (including mammillary nuclei), and inferior colliculi, results in serious disabilities, has an etiology of thiamine deficiency, is treatable with thiamine, and occurs most commonly with alcoholism." | 7.74 | Development and resolution of brain lesions caused by pyrithiamine- and dietary-induced thiamine deficiency and alcohol exposure in the alcohol-preferring rat: a longitudinal magnetic resonance imaging and spectroscopy study. ( Adalsteinsson, E; Bell, RL; Pfefferbaum, A; Sullivan, EV, 2007) |
| "Lactic acidosis and thiamine deficiency were confirmed." | 7.70 | Lactic acidosis caused by thiamine deficiency in a pregnant alcoholic patient. ( Mukunda, BN, 1999) |
| "In two patients admitted to a geriatric ward cardiac failure was based on a thiamine deficiency (wet beri-beri)." | 7.69 | [Failure in self care and heart failure, thiamine deficiency in geriatric patients]. ( Bruijns, E; Jellesma-Eggenkamp, MJ; te Water, W, 1996) |
| " 22 patients showed a moderate or severe thiamine deficiency." | 7.68 | [Thiamine deficiency and brain atrophy in alcoholic patients]. ( Bartels, M; Batra, A; Heimann, H; Mann, K; Schied, HW; Schroth, G; Stetter, F, 1991) |
| " Empirical treatment with thiamine proved to be a cure for the disorder, for it was acute pernicious or fulminating beriberi." | 7.67 | The severe lacticacidosis of thiamine deficiency: acute pernicious or fulminating beriberi. ( Campbell, CH, 1984) |
| "Of 3 alcoholic patients with severe lactic acidosis, one had shoshin beriberi; the second--a beer drinker--presented with convulsions associated with hyponatraemia and complicated by rhabdomyolysis and was not thiamine-deficient; the third patient had convulsions associated with Korsakoff's syndrome and was thiamine-deficient." | 7.67 | [Lactic acidosis treated with thiamine. 3 cases]. ( Berthet, P; Delubac, G; Demingeon, G; Fay, D; Moraillon, X; Thomas, L, 1985) |
| "While thiamine deficiency is commonly recognised in alcoholism, it can present in many other settings where it is often not considered and goes unrecognised." | 7.01 | Thiamine deficiency: a commonly unrecognised but easily treatable condition. ( Jani, A; Johnson, RJ; San Millan, I; Schostak, T, 2023) |
| " Chronic use of ethanol often leads to the development of neurodegenerative syndromes, which cause morphological and functional impairments such as foetal alcohol syndrome in newborns exposed to ethanol during pregnancy, Wernicke-Korsakoff Syndrome and, more rarely, Marchiafava-Bignami disease (MBD)." | 6.55 | Thiamine deficiency, oxidative metabolic pathways and ethanol-induced neurotoxicity: how poor nutrition contributes to the alcoholic syndrome, as Marchiafava-Bignami disease. ( Bezerra, FR; de Oliveira, FR; Fernandes, LMP; Fontes-Júnior, EA; Lima, RR; Maia, CSF; Monteiro, MC; Silva, ML, 2017) |
| "The primary cause of Wernicke-Korsakoff syndrome (WKS) is thiamine deficiency, and more than 90% of cases are reported in alcohol-dependent patients." | 5.51 | What is the optimum thiamine dose to treat or prevent Wernicke's encephalopathy or Wernicke-Korsakoff syndrome? Results of a randomized controlled trial. ( Batey, R; Binks, P; Bowden, SC; Delima, JF; Dingwall, KM, 2022) |
| "Thiamine levels were selectively related to memory performance in the alcoholics." | 5.37 | Signs of preclinical Wernicke's encephalopathy and thiamine levels as predictors of neuropsychological deficits in alcoholism without Korsakoff's syndrome. ( Jackson, K; Pfefferbaum, A; Pitel, AL; Rosenbloom, MJ; Sassoon, SA; Sullivan, EV; Zahr, NM, 2011) |
| "Acetaldehyde is a toxic substance common to heavy drinking of alcohol and heavy smoking of cigarettes." | 5.25 | Protective action of ascorbic acid and sulfur compounds against acetaldehyde toxicity: implications in alcoholism and smoking. ( Gonzales, LJ; Parker, CM; Smith, GG; Sprince, H, 1975) |
| " Baclofen has been shown to promote abstinence, to reduce craving, and to reduce anxiety in alcohol-dependent individuals, and it promises to be a useful agent, although clinical data are limited at present." | 5.24 | Randomized open-label trial of baclofen for relapse prevention in alcohol dependence. ( Arora, S; Elwadhi, D; Gupta, M; Rastogi, R; Verma, P, 2017) |
| "Severe alcoholism can be associated with significant nutritional and vitamin deficiency, especially vitamin B1 (thiamine) which is associated with neurological deficits impacting mood and cognition." | 5.20 | Change in psychiatric symptomatology after benfotiamine treatment in males is related to lifetime alcoholism severity. ( Butler, MG; Manzardo, AM; Pendleton, T; Penick, EC; Poje, A, 2015) |
| "The effect of chronic alcoholism on biochemical evaluation of thiamine status was studied by the concomitant determination of erythrocyte transketolase (ETK) activity, its relative increase by in vitro addition of thiamine diphosphate (TDP effect) and the direct measurement of thiamine and its phosphate esters by high performance liquid chromatography." | 5.08 | Comparison of erythrocyte transketolase activity with thiamine and thiamine phosphate ester levels in chronic alcoholic patients. ( Beyne, P; Delacoux, E; Herve, C; Lettéron, P, 1995) |
| " Furthermore, we suggest thiamine, which is frequently depleted in AUD, to be a key modulator in this process: Thiamine deficiency impairs the integrity of the blood-brain barrier, thereby enabling iron to pass through and accumulate in the brain." | 5.05 | Does thiamine protect the brain from iron overload and alcohol-related dementia? ( Hametner, S; König, D; Listabarth, S; Vyssoki, B, 2020) |
| "Thiamine deficiency (vitamin B1) is common in patients with alcohol dependence." | 4.95 | [Thiamine (vitamin B1) treatment in patients with alcohol dependence]. ( Dervaux, A; Laqueille, X, 2017) |
| "- Patients with alcohol use disorder frequently have a thiamine deficiency." | 4.95 | [Thiamine in patients with alcohol use disorder and Wernicke's encephalopathy]. ( Bekema, JK; Brinkman, DJ; Dekker, MJ; Kuijenhoven, MA; van Agtmael, MA; Wijnia, JW, 2017) |
| "As thiamine deficiency is frequently associated with alcoholism, malnutrition and prolonged vomiting; we recommend prompt treatment of MBD with parenteral thiamine in such subjects." | 4.90 | Diagnosis and management of Marchiafava-Bignami disease: a review of CT/MRI confirmed cases. ( Fujioka, S; Hillbom, M; Juvela, S; Leone, MA; Saloheimo, P; Wszolek, ZK, 2014) |
| "Wernicke encephalopathy is an acute, reversible neuropsychiatric emergency due to thiamine deficiency." | 4.90 | Thiamine in the treatment of Wernicke encephalopathy in patients with alcohol use disorders. ( Dore, G; Latt, N, 2014) |
| "Wernicke-Korsakoff syndrome is a condition with high morbidity and mortality and occurs as a consequence of thiamine deficiency." | 4.89 | [Diagnostics and treatment of Wernicke-Korsakoff syndrome patients with an alcohol abuse]. ( Nilsson, M; Sonne, C, 2013) |
| "Wernicke's encephalopathy (WE) is caused by thiamine (vitamin B1) deficiency and most commonly found in individuals with chronic alcoholism and malnutrition." | 4.87 | [Wernicke's encephalopathy in chronic alcoholics]. ( Blöndal, H; Kjartansson, Ó; Ólafsson, E; Thórarinsson, BL, 2011) |
| "Thiamine deficiency has been specifically linked to the development of Wernicke-Korsakoff syndrome (WK)--a degenerative brain disorder that is typically associated with alcoholic drinking." | 4.83 | A theoretical argument for inherited thiamine insensitivity as one possible biological cause of familial alcoholism. ( Manzardo, AM; Penick, EC, 2006) |
| "Wernicke's encephalopathy (WE) is an acute neuropsychiatric condition due to thiamine deficiency (vitamin B1) most commonly associated with chronic alcohol abuse." | 4.82 | [Prevalence, prophylaxis and treatment of Wernicke encephalopathy. Thiamine, how much and how do we give it?]. ( Daeppen, JB; Meier, S, 2005) |
| " The three principal factors are: alcohol specific neurotoxicity, associated vitamin B1 (thiamine) deficiency (the Wernicke-Korsakoff syndrome) and liver failure secondary to alcoholic cirrhosis." | 4.79 | An introduction to alcohol-induced brain damage and its causes. ( Harper, C; Kril, J, 1994) |
| "There is increasing evidence for the role of thiamine deficiency in ethanol neurotoxicity and in development of alcoholic organic brain disorders other than Wernicke-Korsakoff syndrome [WKS] and cerebellar degeneration." | 4.79 | Thiamine utilization in the pathogenesis of alcohol-induced brain damage. ( Martin, PR; McCool, BA; Pekovich, SR; Singleton, CK; Whetsell, WO, 1994) |
| " The classic triad of confusion, ophthalmoplegia (or nystagmus) and ataxia may be absent, and the history of alcohol abuse or other causes of thiamine deficiency may be unknown." | 4.78 | Wernicke's encephalopathy. ( Lindberg, MC; Oyler, RA, 1990) |
| "We found no cases of Wernicke Encephalopathy (WE) and only one case of thiamine deficiency." | 4.31 | Further evidence of relationship between thiamine blood level and cognition in chronic alcohol-dependent adults: Prospective Pilot Study of an inpatient detoxification with oral supplementation protocol. ( Bonnet, U; Claus, BB; McAnally, H; Pohlmann, L, 2023) |
| "While clinical consequences of thiamine deficiency in alcohol use disorder (AUD) are severe, evidence-based recommendations on dosage, type of administration and duration of thiamine substitution (TS), and its' target levels remain sparse." | 4.31 | Can thiamine substitution restore cognitive function in alcohol use disorder? ( Gleiss, A; Groemer, M; Harrer, C; König, D; Listabarth, S; Marculescu, R; Trojer, A; Vyssoki, B; Weber, S, 2023) |
| "Acute thiamine deficiency can occur in patients with or without history of alcohol abuse and can lead to life-threatening complications." | 4.12 | Clinical diagnosis, outcomes and treatment of thiamine deficiency in a tertiary hospital. ( Balanant, NA; Carette, C; Czernichow, S; Flamarion, E; Jannot, AS; Lucas-Martini, L; Messager, D; Mifsud, F; Poghosyan, T; Rives-Lange, C; Védie, B, 2022) |
| "To describe thiamine supplementation incidence in patients with AUD and various critical illnesses (alcohol withdrawal, septic shock, traumatic brain injury [TBI], and diabetic ketoacidosis [DKA]) in the United States." | 4.12 | Thiamine Supplementation in Patients With Alcohol Use Disorder Presenting With Acute Critical Illness : A Nationwide Retrospective Observational Study. ( Balaji, L; Berg, KM; Donnino, MW; Grossestreuer, AV; Holmberg, MJ; Issa, MS; Kronen, R; Moskowitz, A; Patel, PV; Pawar, RD; Thompson, G, 2022) |
| "To assess relationships of thiamine usage to outcomes of patients hospitalized with alcohol use disorder and pneumonia." | 4.12 | Early treatment with thiamine and mortality among patients with alcohol use disorder who are hospitalized for pneumonia. ( Baron, SW; Deshpande, A; Imrey, PB; Rothberg, MB; Southern, WN; Yu, PC, 2022) |
| "The results indicated that thiamine therapy could be a protective factor for dementia development in patients with alcohol use disorder." | 3.91 | Thiamine for preventing dementia development among patients with alcohol use disorder: A nationwide population-based cohort study. ( Chang, YH; Chen, YY; Chou, WP; Ko, CH; Lin, HC, 2019) |
| " Without apparent etiology of shock, this patient remained hypotensive for 9 days, requiring a vasopressor, despite daily administration of thiamine 600 mg." | 3.88 | Prolonged hypotension associated with Wernicke's encephalopathy. ( Kuriyama, A; Maeda, H; Tanaka, T, 2018) |
| "The effects of chronic EtOH consumption, associated or not with thiamine deficiency (TD), on cognitive impairment, oxidative damage, and β-amyloid (Aβ) peptide accumulation in the brain were investigated in male C57BL/6 mice." | 3.85 | Comparative effects of EtOH consumption and thiamine deficiency on cognitive impairment, oxidative damage, and β-amyloid peptide overproduction in the brain. ( Gao, YQ; Gong, YS; Guo, J; Hou, FL; Hu, K; Liang, CY; Song, FL; Yang, LQ, 2017) |
| ""Shoshin beriberi", which is a fulminant form of cardiovascular beriberi accompanied by hemodynamic deterioration with high cardiac output and decreased systemic blood pressure, caused by thiamine deficiency due to alcoholic abuse or malnutrition, is often difficult to address because of its rarity and non-specific symptoms." | 3.81 | Shoshin Beriberi With Low Cardiac Output and Hemodynamic Deterioration Treated Dramatically by Thiamine Administration. ( Imamura, T; Kinugawa, K, 2015) |
| " We report a patient with Wernicke encephalopathy, a B1 deficiency and pellagra, a niacin deficiency." | 3.81 | Wernicke encephalopathy and pellagra in an alcoholic and malnourished patient. ( Kinoshita, K; Taguchi, S; Terada, N; Tokuda, Y, 2015) |
| "Wernicke's encephalopathy is an acute, potentially life-threatening, neurological syndrome resulting from thiamine deficiency." | 3.80 | [Wernicke's encephalopathy induced by the use of diet pills and unbalanced diet]. ( Aradi, G; Arányi, Z; Bereczki, D; Tóth, A; Várallyay, G; Vastagh, I, 2014) |
| " Given the low risk and cost of BAL testing and thiamine prophylaxis and the high cost of delirium, standard protocols for prophylaxis are essential." | 3.80 | Prevention of delirium in trauma patients: are we giving thiamine prophylaxis a fair chance? ( Ball, CG; Blackmore, C; Kirkpatrick, AW; Niven, D; Ouellet, JF, 2014) |
| " In the UK, it is common practice to treat patients with chronic alcoholism who are admitted to hospital with intravenous vitamins B1, B2, B3, B6 and C for 2-3 days, followed by oral thiamine and vitamin B-compound tablets." | 3.80 | Scurvy in an alcoholic patient treated with intravenous vitamins. ( Ong, J; Randhawa, R, 2014) |
| " Having an acquired immune deficiency syndrome (AIDS)-defining event or hepatitis C was associated with higher Cho; lower Cho levels, however, were associated with low thiamine levels and with highly active antiretroviral HIV treatment (HAART)." | 3.80 | Imaging neuroinflammation? A perspective from MR spectroscopy. ( Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Zahr, NM, 2014) |
| "Korsakoff syndrome is a chronic form of amnesia resulting from thiamine deficiency." | 3.80 | Need for early diagnosis of mental and mobility changes in Wernicke encephalopathy. ( Beuman, C; Bresser, EL; Gerridzen, IJ; Mulder, CL; Oudman, E; van de Wiel, A; Wijnia, JW, 2014) |
| " Chronic alcoholism is usually associated with thiamine deficiency (TD) which is known to induce selective neurodegeneration in the brain." | 3.75 | Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase. ( Fan, Z; Ke, ZJ; Luo, J; Wang, X, 2009) |
| "Wernicke's encephalopathy (WE) is characterized by lesions in thalamus, hypothalamus (including mammillary nuclei), and inferior colliculi, results in serious disabilities, has an etiology of thiamine deficiency, is treatable with thiamine, and occurs most commonly with alcoholism." | 3.74 | Development and resolution of brain lesions caused by pyrithiamine- and dietary-induced thiamine deficiency and alcohol exposure in the alcohol-preferring rat: a longitudinal magnetic resonance imaging and spectroscopy study. ( Adalsteinsson, E; Bell, RL; Pfefferbaum, A; Sullivan, EV, 2007) |
| "Beriberi, thiamine deficiency, is classified as "dry" (neurologic) or "wet" (cardiovascular) and may be mixed." | 3.72 | Occidental beriberi and sudden death. ( Betrosian, AP; Papadimitriou, K; Sevastos, N; Thireos, E; Toutouzas, K; Zabaras, P, 2004) |
| " In the years 1994-1997, 9 patients with no history of alcohol abuse presented with acute signs of ophthalmoplegia or nystagmus and ataxia which resolved within 48 h after intravenous thiamine." | 3.71 | Thiamine-responsive acute neurological disorders in nonalcoholic patients. ( Frisher, S; Herishanu, Y; Ifergane, G; Merkin-Zaborsky, H; Valdman, S; Wirguin, I, 2001) |
| "Wernicke's encephalopathy, a serious neurological disorder caused by thiamine deficiency, is most commonly found in chronic alcoholics." | 3.71 | Wernicke's encephalopathy in a non-alcoholic man: case report and brief review. ( Ameh, J; Hussain, SA; Munir, A; Rosner, F; Sondhi, D, 2001) |
| "Lactic acidosis and thiamine deficiency were confirmed." | 3.70 | Lactic acidosis caused by thiamine deficiency in a pregnant alcoholic patient. ( Mukunda, BN, 1999) |
| "In two patients admitted to a geriatric ward cardiac failure was based on a thiamine deficiency (wet beri-beri)." | 3.69 | [Failure in self care and heart failure, thiamine deficiency in geriatric patients]. ( Bruijns, E; Jellesma-Eggenkamp, MJ; te Water, W, 1996) |
| " 22 patients showed a moderate or severe thiamine deficiency." | 3.68 | [Thiamine deficiency and brain atrophy in alcoholic patients]. ( Bartels, M; Batra, A; Heimann, H; Mann, K; Schied, HW; Schroth, G; Stetter, F, 1991) |
| "The aim of our study was to answer the following questions: (1) is thiamine deficient in chronic excessive drinkers; and (2) is peripheral neuropathy associated with thiamine deficiency or with alcohol intake itself? We performed direct assays of blood concentrations of free thiamine and thiamine phosphate in excessive drinkers with or without peripheral neuropathy and in control subjects." | 3.68 | Blood thiamine and thiamine phosphate concentrations in excessive drinkers with or without peripheral neuropathy. ( Gervaise, G; Houin, G; Poupon, RE; Riant, P; Tillement, JP, 1990) |
| " Empirical treatment with thiamine proved to be a cure for the disorder, for it was acute pernicious or fulminating beriberi." | 3.67 | The severe lacticacidosis of thiamine deficiency: acute pernicious or fulminating beriberi. ( Campbell, CH, 1984) |
| "Of 3 alcoholic patients with severe lactic acidosis, one had shoshin beriberi; the second--a beer drinker--presented with convulsions associated with hyponatraemia and complicated by rhabdomyolysis and was not thiamine-deficient; the third patient had convulsions associated with Korsakoff's syndrome and was thiamine-deficient." | 3.67 | [Lactic acidosis treated with thiamine. 3 cases]. ( Berthet, P; Delubac, G; Demingeon, G; Fay, D; Moraillon, X; Thomas, L, 1985) |
| "Vitamin B1, Folic acid Vitamin B12, whole blood Lead level, and plasma Zinc level were determined in 82 patients admitted to an alcoholism rehabilitation program." | 3.67 | [Subclinical alcoholic optic neuritis without vitamin deficiency]. ( Buisine, A; Dally, S; Delvert, S; Deplus, S; Girre, C; Hispard, E, 1985) |
| " It was not associated with gross liver disease, phenothiazine administration, or familial chorea, and no consistent abnormalities in whole blood thiamine or nicotinic acid, in serum magnesium, or in serum vitamin B(12) levels were present." | 3.65 | Choreoathetotic movement disorder in alcoholism. ( Bolt, JM; Kershaw, PW; Mullin, PJ, 1970) |
| "While thiamine deficiency is commonly recognised in alcoholism, it can present in many other settings where it is often not considered and goes unrecognised." | 3.01 | Thiamine deficiency: a commonly unrecognised but easily treatable condition. ( Jani, A; Johnson, RJ; San Millan, I; Schostak, T, 2023) |
| "We found 12 cases of WE and dysphagia, aged between 12 and 81 years; swallowing problems presented at the onset in nine patients (including the current case report)." | 2.82 | Wernicke Encephalopathy Presenting with Dysphagia: A Case Report and Systematic Literature Review. ( Cornea, A; Lata, I; Rosca, EC; Simu, M, 2022) |
| "Alcohol dependence is associated with severe nutritional and vitamin deficiency." | 2.78 | Double-blind, randomized placebo-controlled clinical trial of benfotiamine for severe alcohol dependence. ( Butler, MG; Campbell, J; He, J; Manzardo, AM; Penick, EC; Poje, A, 2013) |
| "Wernicke-Korsakoff syndrome (WKS) is a neurological disorder typically found in alcohol use disorder." | 2.72 | Wernicke-Korsakoff syndrome despite no alcohol abuse: A summary of systematic reports. ( Oey, MJ; Oudman, E; Postma, A; van Dam, M; Wijnia, JW, 2021) |
| "Wernicke-Korsakoff syndrome (WKS) is most often seen in people who are alcohol dependent." | 2.70 | Thiamin treatment and working memory function of alcohol-dependent people: preliminary findings. ( Ambrose, ML; Bowden, SC; Whelan, G, 2001) |
| " Chronic use of ethanol often leads to the development of neurodegenerative syndromes, which cause morphological and functional impairments such as foetal alcohol syndrome in newborns exposed to ethanol during pregnancy, Wernicke-Korsakoff Syndrome and, more rarely, Marchiafava-Bignami disease (MBD)." | 2.55 | Thiamine deficiency, oxidative metabolic pathways and ethanol-induced neurotoxicity: how poor nutrition contributes to the alcoholic syndrome, as Marchiafava-Bignami disease. ( Bezerra, FR; de Oliveira, FR; Fernandes, LMP; Fontes-Júnior, EA; Lima, RR; Maia, CSF; Monteiro, MC; Silva, ML, 2017) |
| "The dramatic paradox of Wernicke's encephalopathy is that in most cases it is difficult to detect, but early diagnosed cases are quite easy to cure." | 2.49 | [Wernicke encephalopathy and Korsakoff's psychosis: clinical-pathophysiological correlation, diagnostics and treatment]. ( Damulin, IV; Sivolap, IuP, 2013) |
| "Alcoholic ketoacidosis (AKA) is a common reason for investigation and admission of alcohol dependent patients in UK emergency departments." | 2.43 | Alcoholic ketoacidosis. ( Cruickshank, AM; McGuire, LC; Munro, PT, 2006) |
| "Alcohol abuse is one of the most serious problems in public health and the Wernicke-Korsakoff syndrome is one of the gravest consequences of alcoholism." | 2.40 | Wernicke-Korsakoff syndrome. ( Fernandes, JG; Rodnight, R; Zubaran, C, 1997) |
| "Diet has been associated with cancer, heart disease, diabetes, stroke and hypertension, arteriosclerosis, and cirrhosis of the liver." | 2.37 | Implications of nutritional status on human biochemistry, physiology, and health. ( Sauberlich, HE, 1984) |
| "Of 40 patients with ANAN, 21 had alcohol use disorder, 10 were anorexic, and 9 had recently undergone bariatric surgery." | 1.91 | Clinical Spectrum and Prognosis in Patients With Acute Nutritional Axonal Neuropathy. ( Hamel, JI; Logigian, EL, 2023) |
| "Despite guidelines and recommendations, Wernicke's encephalopathy (WE) treatment lacks evidence, leading to clinical practice variability." | 1.91 | Treatment variability and its relationships to outcomes among patients with Wernicke's encephalopathy: A multicenter retrospective study. ( Alvela-Suárez, L; Antolí-Royo, AC; Antúnez-Jorge, E; Castro, J; Chamorro, AJ; Felipe-Pérez, NC; Fernández-Rial, Á; Fernández-Rodríguez, CM; Fernández-Solá, J; Fidalgo-Navarro, A; Gomila-Grange, A; López-Castro, J; Machado-Prieto, B; Marcos, M; Martín-González, MC; Mateos-Díaz, AM; Medina-García, JA; Monte-Secades, R; Muga, R; Novo-Veleiro, I; Polvorosa-Gómez, MA; Prada-González, C; Puerta-Louro, R; Rosón-Hernández, B; Sabio-Repiso, P; Sanvisens-Bergé, A; Seco-Hernández, E; Suárez-Cuervo, C; Valle-Sánchez, MD; Vázquez-Vigo, R, 2023) |
| "Wernicke-Korsakoff syndrome (WKS) is commonly associated with chronic alcohol misuse, a condition known to have multiple detrimental effects on thiamine metabolism." | 1.72 | SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke-Korsakoff's Syndrome. ( Bass, NJ; Guerrini, I; Heydtmann, M; Lightley, I; McHugh, PC; McQuillin, A; Morgan, MY; O'Brien, NL; Quadri, G; Sharp, SI; Smith, I; Thomson, AD, 2022) |
| "Nutritional and toxic optic neuropathy is a rare and challenging diagnosis because of a lack of biomarkers." | 1.56 | Case Report: Nutritional and Toxic Optic Neuropathy: A Diagnostic Dilemma. ( Cervera-Taulet, E; García-Villanueva, C; Mata-Moret, L; Monferrer-Adsuara, C; Ortiz-Salvador, M; Remolí-Sargues, L, 2020) |
| "The role of alcohol abuse is common in the onset of cancer of the upper aerodigestive tract, especially that affecting the tongue, floor of the mouth, palatine tonsil and piriform sinus." | 1.56 | Prevention of withdrawal symptoms in alcoholic patients with head and neck cancer. ( Crescenzi, D; Croce, A; Laus, M; Radici, M; Trignani, M, 2020) |
| "Low thiamine levels were infrequent affecting 3/29 (10%)." | 1.40 | Refeeding syndrome is uncommon in alcoholics admitted to a hospital detoxification unit. ( Gilmour, M; Manning, S; Robinson, GM; Weatherall, M, 2014) |
| "Long term alcohol abuse is associated with deficiencies in essential nutrients and minerals that can cause a variety of medical consequences including accumulation of toxic metals." | 1.39 | Blood thiamine, zinc, selenium, lead and oxidative stress in a population of male and female alcoholics: clinical evidence and gender differences. ( Attilia, ML; Barlocci, E; Ceccanti, M; Ciprotti, M; Draisci, R; Fidente, RM; Fiore, M; Mancinelli, R; Senofonte, O; Vitali, M, 2013) |
| "Thiamine is an essential co-factor for a number of enzymes involved in carbohydrate metabolism and requires optimal levels of magnesium for biological function." | 1.39 | The effect of magnesium administration on erythrocyte transketolase activity in alcoholic patients treated with thiamine. ( Godber, IM; Maguire, D; Peake, RW, 2013) |
| "Thiamine levels were selectively related to memory performance in the alcoholics." | 1.37 | Signs of preclinical Wernicke's encephalopathy and thiamine levels as predictors of neuropsychological deficits in alcoholism without Korsakoff's syndrome. ( Jackson, K; Pfefferbaum, A; Pitel, AL; Rosenbloom, MJ; Sassoon, SA; Sullivan, EV; Zahr, NM, 2011) |
| "Wernicke encephalopathy is a neurological disorder, often caused by a lack of thiamine." | 1.36 | [Confusion, gait ataxia and ophthalmoplegia in a patient with chronic alcohol consumption]. ( Erb, S; Niemann, T; Ott, HW, 2010) |
| "Seven chronic alcoholics recovering from Wernicke's encephalopathy, 14 alcoholic comparisons without Wernicke's encephalopathy, and 14 healthy comparisons underwent functional connectivity MRI scans, as well as verbal and non-verbal memory tests after at least a 1 month abstinence from alcohol." | 1.35 | Mammillothalamic functional connectivity and memory function in Wernicke's encephalopathy. ( Jung, YC; Kim, E; Kim, JJ; Kim, SI; Ku, J; Lee, KS; Lee, SY; Lee, W; Namkoong, K; Park, JY, 2009) |
| "The authors report 13 cases of Gayet-Wernicke's encephalopathy observed in 13 patients of a refugee population." | 1.35 | [Gayet-Wernicke's encephalopathy. A study of 13 cases observed in a refugee population hospitalized at the Conakry Teaching Hospital]. ( Bangoura, SA; Barry, M; Camara, MI; Camara, N; Camara, OB; Cissé, A; Cissé, AF; Da Silva, L; Diallo, LL; Djigué, BS; Koné, S; Koumbassa, ML; Kourouma, S; Morel, Y; Soumah, D; Tafsir, D, 2008) |
| "The presence of Wernicke encephalopathy in alcoholics with diabetic ketoacidosis, suggests that metabolic decompensation is essential in the onset of the disease." | 1.35 | Wernicke encephalopathy in alcoholics with diabetic ketoacidosis. ( Chamorro, AJ; Garcia-Diez, LC; Luna, G; Marcos-Martin, M; Martin-Polo, J, 2009) |
| "The treatment of beriberi is simple and effective and consists of thiamine supplementation in conjunction with diuretic treatment." | 1.33 | [A man with the combination of dry and wet beriberi]. ( Aramideh, M; Cornel, JH; Cox, FM, 2006) |
| "The metabolic effects of chronic alcohol abuse can induce a broad spectrum of disorders." | 1.32 | Ketosis and cardiac failure: common signs of a single condition. ( De Wijngaard, S; Diltoer, MW; Hubloue, I; Huyghens, LP; Lauwers, R; Troubleyn, J; Vercammen, MJ, 2004) |
| "We report 3 patients with alcoholic ketoacidosis (AKA)." | 1.32 | Alcoholic ketoacidosis associated with multiple complications: report of 3 cases. ( Ishikawa, S; Matsuyama, K; Miyazaki, Y; Tanaka, M, 2004) |
| "MRI of the brain demonstrated demyelination, edema and necrosis of the corpus callosum with extensive symmetrical subcortical white matter lesions." | 1.31 | Marchiafava-Bignami disease: a case report. ( Pasutharnchat, N; Phanthumchinda, K, 2002) |
| "PATHOLOGY CORRELATIONS: The Korsakoff syndrome results from cerebral lesions due to thiamine depletion, usually of alcoholic etiology." | 1.31 | [Korsakoff amnesia syndrome]. ( Verstichel, P, 2000) |
| "Treatment by thiamine and alkalinisation permits a spectacular and fast recovery." | 1.31 | [Shoshin beriberi: myth or reality?]. ( Lancellotti, P; Masset, C; Nkoghe, D, 2001) |
| "Twelve patients were identified." | 1.31 | Wernicke encephalopathy in nonalcoholic patients. ( Brick, J; Nestor, S; Ogershok, PR; Rahman, A, 2002) |
| "Body weight was under 90% of the ideal in 8/33 (24%) patients." | 1.30 | Nutritional deficiencies in chronic alcoholics: relation to dietary intake and alcohol consumption. ( Camilo, ME; Cardoso, JN; Cravo, M; Glória, L; Leitão, CN; Mira, FC; Oliveira, AG; Resende, M, 1997) |
| "There was a family history of alcohol dependence in (44%)." | 1.30 | A 3 year case study of alcohol related psychotic disorders at Hospital Seremban. ( Chin, CN; George, S, 1998) |
| "A classic presentation of Wernicke's encephalopathy is reported." | 1.29 | Reversible neurological deficits in a chronic alcohol abuser: a case report of Wernicke's encephalopathy. ( Brady, W; DeBehnke, D; Guido, ME, 1994) |
| "Three were alcohol abusers, and one had prolonged vomiting and anorexia." | 1.29 | Thiamin and thiamin phosphate ester deficiency assessed by high performance liquid chromatography in four clinical cases of Wernicke encephalopathy. ( Bell, H; Bøhmer, T; Tallaksen, CM, 1993) |
| "Analysis of 22 ward admissions for Wernicke's encephalopathy during the same 8-month period revealed that the diagnosis is easily made when neurological deficits (ophthalmoplegia, ataxia) accompany mental changes and when Wernicke's encephalopathy is the predominant illness." | 1.28 | Wernicke's encephalopathy and alcohol-related disease. ( Bramdev, A; Cooper, K; Naidoo, DP, 1991) |
| "Recognition of the cerebral beriberi with ophthalmoplegia as a leading symptom (Wernicke's encephalopathy) is easy." | 1.28 | [Cerebral beriberi with ophthalmoplegia as the leading symptom in an alcoholic patient]. ( Arányi, J, 1991) |
| "Thiamine status was evaluated using the erythrocyte transketolase activation assay in 20 alcoholic patients admitted on a voluntary basis to a Detoxification Unit." | 1.28 | Abnormalities of peripheral nerve conduction in relation to thiamine status in alcoholic patients. ( Bruneau, J; Butterworth, RF; D'Amour, ML, 1991) |
| "Thiamine was transferred from plasma to cerebral tissue by a saturable process with a non-saturable component prevailing at thiamine concentrations above 10-15 microM." | 1.27 | Effect of acute and chronic ethanol administration on the transport of thiamine from plasma to different brain regions of the rat. ( Laforenza, U; Patrini, C; Reggiani, C; Rindi, G, 1988) |
| "The clinical features included confusion and/or clouding of consciousness, marked oppositional hypertonus ('gegenhalten') and myoclonus." | 1.27 | The clinical spectrum of alcoholic pellagra encephalopathy. A retrospective analysis of 22 cases studied pathologically. ( Buge, A; Castaigne, P; Goulon, M; Hausser-Hauw, C; Hauw, JJ; Laplane, D; Lhermitte, F; Serdaru, M, 1988) |
| "Thirty-two cases of Wernicke's encephalopathy were admitted to hospital for treatment in a period of 33 months; this represented a relatively low incidence in total hospital admissions." | 1.27 | Wernicke's encephalopathy in a metropolitan hospital. A prospective study of incidence, characteristics and outcome. ( Breen, K; Currie, J; Wood, B, 1986) |
| "When thiamine was administered in a dose of 50 mg for 10 days, the TDP effect normalized." | 1.26 | Effect of peroral thiamine treatment on thiamine contents and transketolase activity of red blood cells in alcoholic patients. ( Borg, S; Vikander, B; Waldenlind, L, 1981) |
| "The magnesium deficiency is discussed for longstanding malnutrition in both groups, the vitamin B-1 deficiency for an unusual high intake of alcohol before delirium tremens started." | 1.26 | The significance of the serum levels of vitamin B-1 and magnesium in delirium tremens and alcoholism. ( Hoes, MJ, 1979) |
| "Treatment with thiamine hydrochloride resulted in substantial improvement in these thermoregulatory deficits." | 1.26 | Thermolability in Wernicke's encephalopathy. ( Garza, HR; Lipton, JM; Payne, H; Rosenberg, RN, 1978) |
| " Orally administered allithiamine vitamers are therefore recommended for prophylaxis and treatment of thiamine deficits because while having essentially the same biological properties as parenterally administered water-soluble thiamines they have not produced any untoward effects after long-term administration and are far more efficiently utilized." | 1.26 | Absorption, utilization and clinical effectiveness of allithiamines compared to water-soluble thiamines. ( Baker, H; Frank, O, 1976) |
| "Acetaldehyde is a toxic substance common to heavy drinking of alcohol and heavy smoking of cigarettes." | 1.25 | Protective action of ascorbic acid and sulfur compounds against acetaldehyde toxicity: implications in alcoholism and smoking. ( Gonzales, LJ; Parker, CM; Smith, GG; Sprince, H, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 183 (50.69) | 18.7374 |
| 1990's | 39 (10.80) | 18.2507 |
| 2000's | 50 (13.85) | 29.6817 |
| 2010's | 58 (16.07) | 24.3611 |
| 2020's | 31 (8.59) | 2.80 |
| Authors | Studies |
|---|---|
| Agabio, R | 2 |
| Leggio, L | 1 |
| DeFries, T | 1 |
| Leyde, S | 1 |
| Haber, LA | 1 |
| Martin, M | 1 |
| Mifsud, F | 1 |
| Messager, D | 1 |
| Jannot, AS | 1 |
| Védie, B | 1 |
| Balanant, NA | 1 |
| Poghosyan, T | 1 |
| Flamarion, E | 1 |
| Carette, C | 1 |
| Lucas-Martini, L | 1 |
| Czernichow, S | 1 |
| Rives-Lange, C | 1 |
| Pawar, RD | 1 |
| Balaji, L | 1 |
| Grossestreuer, AV | 2 |
| Thompson, G | 1 |
| Holmberg, MJ | 2 |
| Issa, MS | 1 |
| Patel, PV | 2 |
| Kronen, R | 1 |
| Berg, KM | 1 |
| Moskowitz, A | 2 |
| Donnino, MW | 2 |
| Dingwall, KM | 2 |
| Delima, JF | 2 |
| Binks, P | 1 |
| Batey, R | 1 |
| Bowden, SC | 3 |
| Baron, SW | 1 |
| Yu, PC | 1 |
| Imrey, PB | 1 |
| Southern, WN | 1 |
| Deshpande, A | 1 |
| Rothberg, MB | 1 |
| Ambroggio, L | 1 |
| Manning, WA | 1 |
| O'Brien, NL | 1 |
| Quadri, G | 1 |
| Lightley, I | 1 |
| Sharp, SI | 1 |
| Guerrini, I | 1 |
| Smith, I | 1 |
| Heydtmann, M | 1 |
| Morgan, MY | 1 |
| Thomson, AD | 12 |
| Bass, NJ | 1 |
| McHugh, PC | 1 |
| McQuillin, A | 1 |
| Kuzume, D | 1 |
| Morimoto, Y | 1 |
| Yamasaki, M | 1 |
| Hosomi, N | 1 |
| Cornea, A | 1 |
| Lata, I | 1 |
| Simu, M | 1 |
| Rosca, EC | 1 |
| Ganatra, RB | 1 |
| Breu, AC | 1 |
| Ronan, MV | 1 |
| Bonnet, U | 1 |
| Pohlmann, L | 1 |
| McAnally, H | 1 |
| Claus, BB | 1 |
| Listabarth, S | 2 |
| Vyssoki, B | 2 |
| Marculescu, R | 1 |
| Gleiss, A | 1 |
| Groemer, M | 1 |
| Trojer, A | 1 |
| Harrer, C | 1 |
| Weber, S | 1 |
| König, D | 2 |
| Hamel, JI | 1 |
| Logigian, EL | 1 |
| Schostak, T | 1 |
| San Millan, I | 1 |
| Jani, A | 1 |
| Johnson, RJ | 1 |
| Novo-Veleiro, I | 1 |
| Mateos-Díaz, AM | 1 |
| Rosón-Hernández, B | 1 |
| Medina-García, JA | 1 |
| Muga, R | 1 |
| Fernández-Solá, J | 1 |
| Martín-González, MC | 1 |
| Seco-Hernández, E | 1 |
| Suárez-Cuervo, C | 1 |
| Monte-Secades, R | 1 |
| Machado-Prieto, B | 1 |
| Puerta-Louro, R | 1 |
| Prada-González, C | 1 |
| Fernández-Rial, Á | 1 |
| Sabio-Repiso, P | 1 |
| Vázquez-Vigo, R | 1 |
| Antolí-Royo, AC | 1 |
| Gomila-Grange, A | 1 |
| Felipe-Pérez, NC | 1 |
| Sanvisens-Bergé, A | 1 |
| Antúnez-Jorge, E | 1 |
| Fernández-Rodríguez, CM | 1 |
| Alvela-Suárez, L | 1 |
| Fidalgo-Navarro, A | 1 |
| Castro, J | 1 |
| Polvorosa-Gómez, MA | 1 |
| Valle-Sánchez, MD | 1 |
| López-Castro, J | 1 |
| Chamorro, AJ | 2 |
| Marcos, M | 1 |
| Coulbault, L | 1 |
| Ritz, L | 1 |
| Vabret, F | 1 |
| Lannuzel, C | 1 |
| Boudehent, C | 1 |
| Nowoczyn, M | 1 |
| Beaunieux, H | 1 |
| Pitel, AL | 2 |
| Shao, J | 1 |
| Bai, R | 1 |
| Duan, G | 1 |
| Guan, Y | 1 |
| Cui, L | 1 |
| Deng, H | 1 |
| Winters, J | 1 |
| Niespodzany, E | 1 |
| Kini, TA | 1 |
| Othman, BA | 1 |
| Lee, AG | 1 |
| Maguire, D | 2 |
| Talwar, D | 1 |
| Burns, A | 1 |
| Catchpole, A | 1 |
| Stefanowicz, F | 1 |
| Robson, G | 1 |
| Ross, DP | 1 |
| Young, D | 1 |
| Ireland, A | 1 |
| Forrest, E | 1 |
| Galloway, P | 1 |
| Adamson, M | 1 |
| Colgan, E | 1 |
| Bell, H | 3 |
| Orr, L | 1 |
| Kerr, JL | 1 |
| Roussis, X | 1 |
| McMillan, DC | 1 |
| Lewis, MJ | 1 |
| Fujikawa, T | 1 |
| Sogabe, Y | 1 |
| Shakory, S | 1 |
| Kahan, M | 1 |
| Monferrer-Adsuara, C | 1 |
| García-Villanueva, C | 1 |
| Mata-Moret, L | 1 |
| Ortiz-Salvador, M | 1 |
| Remolí-Sargues, L | 1 |
| Cervera-Taulet, E | 1 |
| Rao, R | 2 |
| Laus, M | 1 |
| Trignani, M | 1 |
| Crescenzi, D | 1 |
| Radici, M | 1 |
| Croce, A | 1 |
| Eren, OE | 1 |
| Schöberl, F | 1 |
| Campana, M | 1 |
| Habs, M | 1 |
| Conrad, J | 1 |
| Hametner, S | 1 |
| Kinsley, S | 1 |
| Giovane, RA | 1 |
| Daly, S | 1 |
| Shulman, D | 1 |
| Ikeda, K | 1 |
| Yano, H | 1 |
| Higa, T | 1 |
| Kinjo, M | 1 |
| Oudman, E | 4 |
| Wijnia, JW | 4 |
| Oey, MJ | 1 |
| van Dam, M | 1 |
| Postma, A | 1 |
| Gong, YS | 1 |
| Hu, K | 1 |
| Yang, LQ | 1 |
| Guo, J | 1 |
| Gao, YQ | 1 |
| Song, FL | 1 |
| Hou, FL | 1 |
| Liang, CY | 1 |
| Uber, A | 1 |
| Stankovic, N | 1 |
| Andersen, LW | 1 |
| Maeda, H | 1 |
| Kuriyama, A | 1 |
| Tanaka, T | 1 |
| Gautron, MA | 1 |
| Questel, F | 1 |
| Lejoyeux, M | 1 |
| Bellivier, F | 1 |
| Vorspan, F | 1 |
| Tsai, CY | 1 |
| Huang, PK | 1 |
| Huang, P | 1 |
| Lei, Y | 1 |
| Zheng, MH | 1 |
| Huang, W | 1 |
| Zhang, J | 1 |
| Lu, Y | 1 |
| Chou, WP | 1 |
| Chang, YH | 2 |
| Lin, HC | 1 |
| Chen, YY | 1 |
| Ko, CH | 1 |
| Ajob, L | 2 |
| Brännström, I | 2 |
| Ott, M | 2 |
| Werneke, U | 2 |
| Linder, LM | 1 |
| Robert, S | 1 |
| Mullinax, K | 1 |
| Hayes, G | 1 |
| Kamp, D | 1 |
| Utlu, A | 1 |
| Burchert, K | 1 |
| Franke, PE | 1 |
| Yoon, C | 1 |
| Gedzior, J | 1 |
| DePry, D | 1 |
| Jiawan, A | 1 |
| Tandjung, K | 1 |
| Mancinelli, R | 2 |
| Barlocci, E | 1 |
| Ciprotti, M | 1 |
| Senofonte, O | 1 |
| Fidente, RM | 1 |
| Draisci, R | 1 |
| Attilia, ML | 2 |
| Vitali, M | 1 |
| Fiore, M | 1 |
| Ceccanti, M | 2 |
| Längle, G | 1 |
| Pollmächer, T | 1 |
| Nilsson, M | 1 |
| Sonne, C | 1 |
| Sivolap, IuP | 1 |
| Damulin, IV | 1 |
| Peake, RW | 1 |
| Godber, IM | 1 |
| Hillbom, M | 1 |
| Saloheimo, P | 1 |
| Fujioka, S | 1 |
| Wszolek, ZK | 1 |
| Juvela, S | 1 |
| Leone, MA | 1 |
| Manzardo, AM | 3 |
| He, J | 1 |
| Poje, A | 2 |
| Penick, EC | 3 |
| Campbell, J | 1 |
| Butler, MG | 2 |
| Bravatà, V | 1 |
| Minafra, L | 1 |
| Callari, G | 1 |
| Gelfi, C | 1 |
| Edoardo Grimaldi, LM | 1 |
| Tóth, A | 1 |
| Aradi, G | 1 |
| Várallyay, G | 1 |
| Arányi, Z | 1 |
| Bereczki, D | 1 |
| Vastagh, I | 1 |
| Duray, MC | 1 |
| De Maeseneire, C | 1 |
| Rutgers, MP | 1 |
| Gille, M | 1 |
| Blackmore, C | 1 |
| Ouellet, JF | 1 |
| Niven, D | 1 |
| Kirkpatrick, AW | 1 |
| Ball, CG | 1 |
| Ong, J | 1 |
| Randhawa, R | 1 |
| Manning, S | 1 |
| Gilmour, M | 1 |
| Weatherall, M | 1 |
| Robinson, GM | 1 |
| Cresce, ND | 1 |
| McManus, KA | 1 |
| Sifri, CD | 1 |
| Wilson, BB | 1 |
| Latt, N | 1 |
| Dore, G | 1 |
| Zahr, NM | 3 |
| Mayer, D | 1 |
| Rohlfing, T | 1 |
| Sullivan, EV | 4 |
| Pfefferbaum, A | 4 |
| Bresser, EL | 1 |
| Gerridzen, IJ | 1 |
| van de Wiel, A | 1 |
| Beuman, C | 1 |
| Mulder, CL | 1 |
| Gent, D | 1 |
| Batey, RG | 1 |
| Pendleton, T | 1 |
| Restivo, A | 1 |
| Carta, MG | 1 |
| Farci, AMG | 1 |
| Saiu, L | 1 |
| Gessa, GL | 1 |
| Imamura, T | 1 |
| Kinugawa, K | 1 |
| Terada, N | 1 |
| Kinoshita, K | 1 |
| Taguchi, S | 1 |
| Tokuda, Y | 1 |
| Wilson, EC | 1 |
| Stanley, G | 1 |
| Mirza, Z | 1 |
| McNamara, PH | 1 |
| Williams, J | 1 |
| McCabe, DJ | 1 |
| Walsh, RA | 1 |
| Kuypers, MI | 1 |
| Lieshoud, JR | 1 |
| van der Linden, PD | 1 |
| Touw, DJ | 1 |
| Deenik, W | 1 |
| Boeke, GM | 1 |
| Pinter, G | 1 |
| Borbely, K | 1 |
| Peter, L | 1 |
| Mehrzad, R | 1 |
| Ho, MG | 1 |
| Benatti, M | 1 |
| Pazin-Filho, A | 1 |
| Miranda, CH | 1 |
| Gupta, M | 1 |
| Verma, P | 1 |
| Rastogi, R | 1 |
| Arora, S | 1 |
| Elwadhi, D | 1 |
| Dervaux, A | 2 |
| Laqueille, X | 1 |
| Brinkman, DJ | 1 |
| Bekema, JK | 1 |
| Kuijenhoven, MA | 1 |
| Dekker, MJ | 1 |
| van Agtmael, MA | 1 |
| Fernandes, LMP | 1 |
| Bezerra, FR | 1 |
| Monteiro, MC | 1 |
| Silva, ML | 1 |
| de Oliveira, FR | 1 |
| Lima, RR | 1 |
| Fontes-Júnior, EA | 1 |
| Maia, CSF | 1 |
| Frankenburg, FR | 1 |
| Kim, E | 1 |
| Ku, J | 1 |
| Namkoong, K | 1 |
| Lee, W | 1 |
| Lee, KS | 1 |
| Park, JY | 1 |
| Lee, SY | 1 |
| Kim, JJ | 1 |
| Kim, SI | 1 |
| Jung, YC | 1 |
| Raina, S | 1 |
| Mahesh, DM | 1 |
| Mahajan, J | 1 |
| Kaushal, SS | 1 |
| Gupta, D | 1 |
| Dhiman, DS | 1 |
| Cissé, AF | 1 |
| Camara, N | 1 |
| Diallo, LL | 1 |
| Morel, Y | 1 |
| Koné, S | 1 |
| Camara, MI | 1 |
| Koumbassa, ML | 1 |
| Tafsir, D | 1 |
| Soumah, D | 1 |
| Djigué, BS | 1 |
| Camara, OB | 1 |
| Barry, M | 1 |
| Bangoura, SA | 1 |
| Kourouma, S | 1 |
| Da Silva, L | 1 |
| Cissé, A | 1 |
| Ke, ZJ | 1 |
| Wang, X | 1 |
| Fan, Z | 1 |
| Luo, J | 1 |
| Kobayashi, Z | 1 |
| Tsuchiya, K | 1 |
| Takahashi, M | 1 |
| Yokota, O | 1 |
| Taki, K | 1 |
| Ishizu, H | 1 |
| Arai, T | 1 |
| Akiyama, H | 1 |
| Mizusawa, H | 1 |
| Marcos-Martin, M | 1 |
| Martin-Polo, J | 1 |
| Garcia-Diez, LC | 1 |
| Luna, G | 1 |
| Ward, D | 1 |
| Murch, N | 1 |
| Agarwal, G | 1 |
| Bell, D | 1 |
| Niemann, T | 1 |
| Erb, S | 1 |
| Ott, HW | 1 |
| Luong, R | 1 |
| Jackson, K | 1 |
| Sassoon, SA | 1 |
| Rosenbloom, MJ | 1 |
| Thórarinsson, BL | 1 |
| Ólafsson, E | 1 |
| Kjartansson, Ó | 1 |
| Blöndal, H | 1 |
| Talbot, PA | 1 |
| Demirkol, A | 1 |
| Conigrave, K | 1 |
| Haber, P | 1 |
| O'Flynn, N | 1 |
| Sriram, K | 1 |
| Manzanares, W | 1 |
| Joseph, K | 1 |
| Geisler, F | 1 |
| Smyth, M | 1 |
| Oechtering, J | 1 |
| Tuetuencue, S | 1 |
| Klostermann, F | 1 |
| Nolte, CH | 1 |
| Pasutharnchat, N | 1 |
| Phanthumchinda, K | 1 |
| Ito, M | 1 |
| Tanabe, Y | 1 |
| Suzuki, K | 1 |
| Kumakura, M | 1 |
| Aizawa, Y | 1 |
| Heap, LC | 1 |
| Pratt, OE | 3 |
| Ward, RJ | 1 |
| Waller, S | 1 |
| Shaw, GK | 6 |
| Peters, TJ | 1 |
| Rugilo, CA | 1 |
| Roca, MC | 1 |
| Zurrú, MC | 1 |
| Gatto, EM | 1 |
| Hensel, M | 1 |
| Kox, WJ | 1 |
| Guiducci, MS | 1 |
| Sasso, GF | 1 |
| Sebastiani, G | 1 |
| Allen, JP | 1 |
| CHATAGNON, PA | 1 |
| GARNIER, M | 1 |
| CHANOIT, P | 1 |
| WESTERFELD, WW | 1 |
| LAWROW, J | 1 |
| JOHNSTON, M | 1 |
| BERTHIER, C | 1 |
| BARNAUD, J | 1 |
| LANGERON, L | 1 |
| PERON, N | 1 |
| Zieve, L | 2 |
| Hill, E | 1 |
| SALZBERGER, GJ | 1 |
| Baker, H | 10 |
| Frank, O | 9 |
| Ziffer, H | 1 |
| Goldfarb, S | 1 |
| Leevy, CM | 10 |
| Sobotka, H | 1 |
| VILLARD, HP | 1 |
| BEAUREGARD, JM | 1 |
| KANTHER, R | 1 |
| FENNELLY, J | 2 |
| SUKHORUKOVA, LI | 1 |
| MARGAT, MM | 1 |
| LUSSANA, S | 1 |
| BAILEY, G | 1 |
| ROSENBAUM, JM | 1 |
| ANDERSON, B | 1 |
| BUCKLE, RM | 2 |
| Tenhove, W | 1 |
| Cherrick, GR | 1 |
| Sakata, S | 1 |
| Nakamura, J | 1 |
| Koguchi, K | 1 |
| Nakatsuji, Y | 1 |
| Abe, K | 1 |
| Sakoda, S | 1 |
| GREGORY, I | 1 |
| Celik, Y | 1 |
| Kaya, M | 1 |
| Betrosian, AP | 1 |
| Thireos, E | 1 |
| Toutouzas, K | 1 |
| Zabaras, P | 1 |
| Papadimitriou, K | 1 |
| Sevastos, N | 1 |
| Diltoer, MW | 1 |
| Troubleyn, J | 1 |
| Lauwers, R | 1 |
| De Wijngaard, S | 1 |
| Vercammen, MJ | 1 |
| Hubloue, I | 1 |
| Huyghens, LP | 1 |
| Jackson, R | 1 |
| Teece, S | 1 |
| Stacey, PS | 1 |
| Sullivan, KA | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effectiveness of Benfotiamine in Reducing Abusive Drinking Among Family History Positive and Negative Alcoholics[NCT00680121] | Phase 4 | 120 participants (Actual) | Interventional | 2008-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The alcoholism severity scale measures the severity of a person's dependence to alcohol. The scale ranges from a score of 0 (least severe) to 33 (most severe). The higher the score the worse the dependence. (NCT00680121)
Timeframe: 6 Months
| Intervention | scores on a scale (Mean) |
|---|---|
| Control Group | 14.0 |
| Benfotiamine | 10.7 |
Scale measures impulsiveness. It includes 30 items that are scored to yield six first-order factors (attention, motor, self-control, cognitive complexity, perseverance, and cognitive instability impulsiveness) and three second-order factors (attentional, motor, and non-planning impulsiveness). Items are scored on a 4 point scale with 1 point equaling rarely/never up to 4 points equaling almost always/always. Total impulsivity score ranges from 30 (least impulsive) to 120 (most impulsive). The higher the score the higher the level of impulsiveness. (NCT00680121)
Timeframe: 6 Months
| Intervention | scores on a scale (Mean) |
|---|---|
| Control Group | 65.0 |
| Benfotiamine | 65.4 |
measured as standard drinks of alcohol per day (SD/day) (NCT00680121)
Timeframe: Change from Baseline to 6 Months
| Intervention | alcoholic drinks per day (Mean) |
|---|---|
| Control Group | -3.4 |
| Benfotiamine | -3.0 |
The SCL-90 is a brief multidimensional self-report inventory that screens for nine symptoms of psychopathology and provides three global distress indicators. It provides an overview of symptom severity and intensity. The outcome measures psychiatric symptoms using a 30-item scale reported as t-scores relative to a normative population. (NCT00680121)
Timeframe: 6 Months
| Intervention | t-score (Mean) |
|---|---|
| Control Group | 1.02 |
| Benfotiamine | 1.04 |
51 reviews available for thiamine and Alcohol Abuse
| Article | Year |
|---|---|
Wernicke Encephalopathy Presenting with Dysphagia: A Case Report and Systematic Literature Review.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alcoholism; Child; Deglutition Disorders; Humans; Middle | 2022 |
Thiamine deficiency: a commonly unrecognised but easily treatable condition.
Topics: Acidosis, Lactic; Alcoholism; Food; Humans; Thiamine; Thiamine Deficiency | 2023 |
Alcoholism and nutrition: a review of vitamin supplementation and treatment.
Topics: Alcoholism; Animals; Avitaminosis; Dietary Supplements; Disease Models, Animal; Humans; Niacin; Nutr | 2020 |
Does thiamine protect the brain from iron overload and alcohol-related dementia?
Topics: Alcoholism; Animals; Brain; Dementia; Humans; Iron Overload; Thiamine; Thiamine Deficiency | 2020 |
Wernicke-Korsakoff syndrome despite no alcohol abuse: A summary of systematic reports.
Topics: Adult; Alcoholism; Ataxia; Child; Female; Humans; Korsakoff Syndrome; Pregnancy; Thiamine; Thiamine | 2021 |
Wet beriberi with multiple organ failure remarkably reversed by thiamine administration: A case report and literature review.
Topics: Adult; Alcoholism; Beriberi; Cardiac Output; Humans; Male; Multiple Organ Failure; Prisoners; Thiami | 2018 |
[Diagnostics and treatment of Wernicke-Korsakoff syndrome patients with an alcohol abuse].
Topics: Alcoholism; Humans; Korsakoff Syndrome; Thiamine; Thiamine Deficiency; Vitamin B Complex; Wernicke E | 2013 |
[Wernicke encephalopathy and Korsakoff's psychosis: clinical-pathophysiological correlation, diagnostics and treatment].
Topics: Alcoholism; Cognition; Dopamine Agents; Drug Therapy, Combination; Early Diagnosis; Humans; Infusion | 2013 |
Diagnosis and management of Marchiafava-Bignami disease: a review of CT/MRI confirmed cases.
Topics: Alcoholism; Corpus Callosum; Diagnosis, Differential; Humans; Magnetic Resonance Imaging; Marchiafav | 2014 |
Thiamine in the treatment of Wernicke encephalopathy in patients with alcohol use disorders.
Topics: Alcoholism; Disease Progression; Dose-Response Relationship, Drug; Early Diagnosis; Humans; Korsakof | 2014 |
[Thiamine (vitamin B1) treatment in patients with alcohol dependence].
Topics: Alcoholic Neuropathy; Alcoholism; Cardiomyopathy, Alcoholic; Diagnosis, Differential; Drug Administr | 2017 |
[Thiamine in patients with alcohol use disorder and Wernicke's encephalopathy].
Topics: Alcoholism; Humans; Thiamine; Thiamine Deficiency; Wernicke Encephalopathy | 2017 |
Thiamine deficiency, oxidative metabolic pathways and ethanol-induced neurotoxicity: how poor nutrition contributes to the alcoholic syndrome, as Marchiafava-Bignami disease.
Topics: Alcohol Drinking; Alcoholism; Ethanol; Marchiafava-Bignami Disease; Neurotoxicity Syndromes; Oxidati | 2017 |
[Wernicke's encephalopathy in chronic alcoholics].
Topics: Alcoholism; Humans; Magnesium Compounds; Magnesium Deficiency; Magnetic Resonance Imaging; Predictiv | 2011 |
Thiamine in nutrition therapy.
Topics: Alcoholism; Humans; Nutrition Therapy; Nutritional Status; Thiamine; Thiamine Deficiency; Vitamin B | 2012 |
Thiamine. Monograph.
Topics: Affect; Alcoholism; Female; Heart Failure; HIV Infections; Humans; Pregnancy; Pregnancy Complication | 2003 |
[Delirium tremens].
Topics: Alcohol Withdrawal Delirium; Alcoholism; Antidepressive Agents; Antipsychotic Agents; Benzodiazepine | 2003 |
Best evidence topic report. Oral or intravenous thiamine in the emergency department.
Topics: Administration, Oral; Alcoholism; Emergency Service, Hospital; Evidence-Based Medicine; Humans; Infu | 2004 |
Alcohol and the nervous system.
Topics: Alcohol Drinking; Alcohol Withdrawal Seizures; Alcoholic Intoxication; Alcoholism; Central Nervous S | 2004 |
[Prevalence, prophylaxis and treatment of Wernicke encephalopathy. Thiamine, how much and how do we give it?].
Topics: Alcoholism; Humans; Infusions, Parenteral; Prevalence; Thiamine; Wernicke Encephalopathy | 2005 |
Alcoholic ketoacidosis.
Topics: Acidosis; Acute Disease; Alcoholism; Emergency Service, Hospital; Fluid Therapy; Humans; Ketosis; NA | 2006 |
A theoretical argument for inherited thiamine insensitivity as one possible biological cause of familial alcoholism.
Topics: Alcoholism; Animals; Cerebellum; Dopamine; Humans; Nutritional Physiological Phenomena; Thiamine; Th | 2006 |
[Alcohol-related disorders].
Topics: Alcohol Amnestic Disorder; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholism; Anti-Anxie | 2006 |
Thiamin--the interaction of aging, alcoholism, and malabsorption in various populations.
Topics: Aged; Aging; Alcoholism; Animals; Developing Countries; Diet; Energy Intake; Europe; Humans; Intesti | 1984 |
Mechanisms of thiamin deficiency in chronic alcoholism.
Topics: Alcoholism; Ethanol; Humans; Intestinal Absorption; Intestine, Small; Liver; Membrane Fluidity; Mode | 1980 |
Clinical chemistry of thiamin.
Topics: Adult; Aged; Aging; Alcoholism; Anemia, Megaloblastic; Animals; Beriberi; Biological Assay; Biologic | 1983 |
Implications of nutritional status on human biochemistry, physiology, and health.
Topics: Alcoholism; Anemia, Hypochromic; Animals; Ascorbic Acid; Avitaminosis; Climate; Dietary Fats; Female | 1984 |
Thiamin in the elderly--relation to alcoholism and to neurological degenerative disease.
Topics: Adolescent; Adult; Aged; Aging; Alcoholism; Animals; Biological Availability; Child; Child, Preschoo | 1982 |
Vitamins and alcoholism. IV. Thiamin.
Topics: Alcoholism; Animals; Ethanol; Female; Humans; Intestinal Absorption; Liver; Male; Pyruvates; Rats; T | 1980 |
Thiamin deficiency and alcoholism.
Topics: Alcoholism; Dementia; Diet; Digestive System; Heart Diseases; Humans; Intestinal Absorption; Phospho | 1982 |
An introduction to alcohol-induced brain damage and its causes.
Topics: Alcoholism; Animals; Brain; Brain Injuries; Ethanol; Humans; Liver Cirrhosis, Alcoholic; Organ Size; | 1994 |
Thiamine utilization in the pathogenesis of alcohol-induced brain damage.
Topics: Alcohol Amnestic Disorder; Alcoholism; Animals; Brain Injuries; Humans; Thiamine; Thiamine Deficienc | 1994 |
Wernicke-Korsakoff syndrome.
Topics: Alcohol Amnestic Disorder; Alcoholism; History, 19th Century; Humans; Metabolic Diseases; Prognosis; | 1997 |
[Nutritional disorders and myocardial disease].
Topics: Alcoholism; Avitaminosis; Beriberi; Cardiomyopathies; Diagnosis, Differential; Humans; Nutrition Dis | 1996 |
[Inpatient treatment of alcohol dependence].
Topics: Alcohol Deterrents; Alcoholism; Anti-Anxiety Agents; Benzodiazepines; Disulfiram; Ethanol; Hospitali | 1997 |
Do diuretics cause thiamine deficiency?
Topics: Alcoholism; Diuretics; Heart Failure; Humans; Kidney; Thiamine; Thiamine Deficiency | 1999 |
Intracranial voyeurism: revealing the mammillary bodies in alcoholism.
Topics: Alcoholism; Humans; Korsakoff Syndrome; Mammillary Bodies; Thiamine; Wernicke Encephalopathy | 1999 |
[Alcohol intake and nutrition].
Topics: Alcohol Drinking; Alcoholic Beverages; Alcoholism; Animals; Copper; Feeding Behavior; Female; Humans | 2000 |
Neurotoxicity and neurocognitive impairments with alcohol and drug-use disorders: potential roles in addiction and recovery.
Topics: Alcoholism; Animals; Brain; Cognition Disorders; Humans; Nervous System Diseases; Substance-Related | 2001 |
Molecular mechanisms of thiamine utilization.
Topics: Alcoholism; Animals; Apoptosis; Gene Expression Regulation; Humans; Korsakoff Syndrome; Neurons; Oxi | 2001 |
[Clinical aspects of the wernicke-korsakoff-syndrome (author's transl)].
Topics: Adult; Aged; Alcohol Amnestic Disorder; Alcoholism; Brain Stem; Diagnosis, Differential; Humans; Mal | 1976 |
Wernicke's encephalopathy.
Topics: Acute Disease; Aged; Alcohol Amnestic Disorder; Alcoholism; Diagnosis, Differential; Female; Humans; | 1990 |
Alcohol and thiamine of the brain.
Topics: Alcoholism; Animals; Brain; Humans; Phosphoric Monoester Hydrolases; Thiamin Pyrophosphokinase; Thia | 1989 |
Current concepts. Wernicke's encephalopathy.
Topics: Alcoholism; Ataxia; Brain; Coma; Confusion; Humans; Hypotension; Hypothermia; Nutrition Disorders; O | 1985 |
Thiamin status in Australia.
Topics: Alcohol Amnestic Disorder; Alcoholic Beverages; Alcoholism; Australia; Beriberi; Bread; Diet; Feedin | 1985 |
Nutritional aspects of alcohol consumption.
Topics: Alcoholism; Animals; Cholecalciferol; Choline Deficiency; Ethanol; Fatty Liver; Glutamates; Humans; | 1972 |
Chronic central nervous system toxicity of alcohol.
Topics: Alcohol Amnestic Disorder; Alcoholism; Animals; Behavior, Animal; Brain; Brain Diseases; Central Ner | 1973 |
[Alcoholic cardiomyopathy].
Topics: Alcoholism; Diagnosis, Differential; Electrocardiography; Heart; Heart Diseases; Humans; Magnesium D | 1969 |
[Is the diagnosis of alcoholic cardiomyopathy justified].
Topics: Alcoholism; Cardiac Output; Cardiomyopathies; Chronic Disease; Diet; Humans; Intestinal Absorption; | 1970 |
[Modern thiamine therapy].
Topics: Alcoholism; Analgesics; Animals; Anura; Child; Constipation; Cyanates; Dogs; Female; Furans; Gastroi | 1967 |
Influence of malnutrition and alcohol on thiamine absorption.
Topics: Aged; Alcoholism; Celiac Disease; Dose-Response Relationship, Drug; Ethanol; Humans; Intestinal Abso | 1971 |
12 trials available for thiamine and Alcohol Abuse
| Article | Year |
|---|---|
What is the optimum thiamine dose to treat or prevent Wernicke's encephalopathy or Wernicke-Korsakoff syndrome? Results of a randomized controlled trial.
Topics: Alcoholism; Ethanol; Humans; Korsakoff Syndrome; Thiamine; Thiamine Deficiency; Wernicke Encephalopa | 2022 |
Double-blind, randomized placebo-controlled clinical trial of benfotiamine for severe alcohol dependence.
Topics: Adult; Alcoholism; Algorithms; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind M | 2013 |
Change in psychiatric symptomatology after benfotiamine treatment in males is related to lifetime alcoholism severity.
Topics: Adult; Alcoholism; Depression; Double-Blind Method; Humans; Male; Middle Aged; Psychiatric Status Ra | 2015 |
Randomized open-label trial of baclofen for relapse prevention in alcohol dependence.
Topics: Adult; Alcohol Abstinence; Alcohol Drinking; Alcoholism; Anxiety; Baclofen; Craving; GABA-B Receptor | 2017 |
Comparison of erythrocyte transketolase activity with thiamine and thiamine phosphate ester levels in chronic alcoholic patients.
Topics: Adult; Aged; Aged, 80 and over; Alcoholism; Erythrocytes; Female; Humans; Male; Middle Aged; Thiamin | 1995 |
Alcohol, thiamin deficiency, and neuropsychological disorders.
Topics: Adult; Alcohol Amnestic Disorder; Alcoholism; Brain Injuries; Cognition Disorders; Double-Blind Meth | 1994 |
[Medicamentous therapy of alcoholic polyneuropathy. Randomized double-blind study comparing 2 vitamin B preparations and a nucleotide preparation].
Topics: Adult; Alcoholism; Cytidine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combin | 1996 |
Thiamin treatment and working memory function of alcohol-dependent people: preliminary findings.
Topics: Adult; Alcoholism; Analysis of Variance; Ataxia; Double-Blind Method; Humans; Korsakoff Syndrome; Me | 2001 |
Tissue thiamin levels of hospitalised alcoholics before and after oral or parenteral vitamins.
Topics: Administration, Oral; Adult; Alcoholism; Chromatography, High Pressure Liquid; Erythrocytes; Female; | 1988 |
Patterns of 35S-thiamine hydrochloride absorption in the malnourished alcoholic patient.
Topics: Alcoholism; Biopsy; Catheterization; Clinical Trials as Topic; Ethanol; Humans; Intestinal Absorptio | 1970 |
Evaluating changes in symptoms during acute alcohol withdrawal.
Topics: Affect; Alcoholism; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Female; Humans; Hydr | 1971 |
[Features of active anti-alcohol therapy of patients who have suffered alcoholic psychoses].
Topics: Acute Disease; Adult; Alcoholism; Apomorphine; Calcium; Cardiovascular Diseases; Chlorpromazine; Dis | 1969 |
298 other studies available for thiamine and Alcohol Abuse
| Article | Year |
|---|---|
Thiamine administration to
Topics: Alcohol Drinking; Alcoholism; Humans; Thiamine | 2021 |
Things We Do for No Reason™: Prescribing Thiamine, Folate and Multivitamins on Discharge for Patients With Alcohol Use Disorder.
Topics: Alcoholism; Folic Acid; Humans; Patient Discharge; Thiamine; Thiamine Deficiency | 2021 |
Clinical diagnosis, outcomes and treatment of thiamine deficiency in a tertiary hospital.
Topics: Acute Disease; Alcoholism; Brain; Dietary Supplements; Female; Humans; Magnetic Resonance Imaging; M | 2022 |
Thiamine Supplementation in Patients With Alcohol Use Disorder Presenting With Acute Critical Illness : A Nationwide Retrospective Observational Study.
Topics: Adult; Alcoholism; Critical Illness; Dietary Supplements; Humans; Male; Middle Aged; Retrospective S | 2022 |
Early treatment with thiamine and mortality among patients with alcohol use disorder who are hospitalized for pneumonia.
Topics: Adult; Alcoholism; Benzodiazepines; Hospital Mortality; Hospitalization; Humans; Length of Stay; Pne | 2022 |
Propensity scores to estimate treatment effects of thiamine in alcohol use disorder.
Topics: Alcoholism; Humans; Propensity Score; Thiamine; Thiamine Deficiency | 2022 |
SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke-Korsakoff's Syndrome.
Topics: Alcoholism; Ethanol; Folic Acid; Genetic Variation; HEK293 Cells; Humans; Korsakoff Syndrome; Reduce | 2022 |
[Wernicke encephalopathy with lesions in the bilateral abducens nuclei: a case report].
Topics: Abducens Nerve Diseases; Adult; Alcoholism; Dizziness; Humans; Magnetic Resonance Imaging; Male; Thi | 2022 |
Which patients hospitalized with alcohol withdrawal syndrome should receive high-dose parenteral thiamine?
Topics: Alcoholism; Humans; Substance Withdrawal Syndrome; Thiamine; Thiamine Deficiency | 2023 |
Further evidence of relationship between thiamine blood level and cognition in chronic alcohol-dependent adults: Prospective Pilot Study of an inpatient detoxification with oral supplementation protocol.
Topics: Adult; Alcoholism; Cognition; Dietary Supplements; Female; Humans; Inpatients; Male; Middle Aged; Pi | 2023 |
Can thiamine substitution restore cognitive function in alcohol use disorder?
Topics: Alcoholism; Cognition; Humans; Korsakoff Syndrome; Thiamine; Thiamine Deficiency; Thiamine Pyrophosp | 2023 |
Clinical Spectrum and Prognosis in Patients With Acute Nutritional Axonal Neuropathy.
Topics: Alcoholism; Folic Acid; Humans; Micronutrients; Neuralgia; Prognosis; Thiamine; Vitamins | 2023 |
Treatment variability and its relationships to outcomes among patients with Wernicke's encephalopathy: A multicenter retrospective study.
Topics: Alcoholism; Folic Acid Deficiency; Humans; Retrospective Studies; Thiamine; Thiamine Deficiency; Wer | 2023 |
Thiamine and phosphate esters concentrations in whole blood and serum of patients with alcohol use disorder: a relation with cognitive deficits.
Topics: Adult; Alcoholism; Cognitive Dysfunction; Esters; Female; Humans; Male; Middle Aged; Neuropsychologi | 2021 |
Intermittent alien hand syndrome caused by Marchiafava-Bignami disease: A case report.
Topics: Alcoholism; Alien Limb Phenomenon; Corpus Callosum; Humans; Magnetic Resonance Imaging; Male; Marchi | 2019 |
Rapid same-day resolution of internuclear ophthalmoplegia in Wernicke encephalopathy following parenteral high dose thiamine.
Topics: Adult; Alcoholism; Humans; Infusions, Parenteral; Magnetic Resonance Imaging; Male; Ocular Motility | 2020 |
A prospective evaluation of thiamine and magnesium status in relation to clinicopathological characteristics and 1-year mortality in patients with alcohol withdrawal syndrome.
Topics: Adult; Alcoholism; Female; Humans; Magnesium; Male; Middle Aged; Prospective Studies; Substance With | 2019 |
Wernicke encephalopathy.
Topics: Adult; Alcoholism; Female; Humans; Magnetic Resonance Imaging; Thiamine; Thiamine Deficiency; Treatm | 2020 |
Thiamine in the management of alcohol use disorders.
Topics: Alcoholism; Humans; Thiamine; Vitamin B Complex | 2020 |
Response.
Topics: Alcoholism; Humans; Thiamine | 2020 |
Case Report: Nutritional and Toxic Optic Neuropathy: A Diagnostic Dilemma.
Topics: Alcoholism; Folic Acid; Humans; Male; Middle Aged; Nutrition Disorders; Papilledema; Smoking; Thiami | 2020 |
Thiamine as a Modifying Factor for Alcohol-Related Intracranial Haemorrhage.
Topics: Alcoholism; Humans; Intracranial Hemorrhages; Thiamine; Thiamine Deficiency; Vitamin B Complex | 2020 |
Prevention of withdrawal symptoms in alcoholic patients with head and neck cancer.
Topics: Alcoholism; Antipsychotic Agents; Cancer Care Facilities; Cultural Characteristics; Head and Neck Ne | 2020 |
A unique MRI-pattern in alcohol-associated Wernicke encephalopathy.
Topics: Adult; Alcoholism; Female; Humans; Magnetic Resonance Imaging; Thiamine; Wernicke Encephalopathy | 2020 |
Rare case of Marchiafava-Bignami disease due to thiamine deficiency and malnutrition.
Topics: Aged; Alcoholism; Corpus Callosum; Diagnosis, Differential; Female; Humans; Magnetic Resonance Imagi | 2020 |
Nystagmus in non-alcoholic Wernicke encephalopathy.
Topics: Alcoholism; Humans; Korsakoff Syndrome; Nystagmus, Pathologic; Thiamine; Wernicke Encephalopathy | 2021 |
Bariatric Wernicke's encephalopathy.
Topics: Alcoholism; Bariatrics; Humans; Thiamine; Wernicke Encephalopathy | 2021 |
Comparative effects of EtOH consumption and thiamine deficiency on cognitive impairment, oxidative damage, and β-amyloid peptide overproduction in the brain.
Topics: Alcohol Drinking; Alcoholism; Amyloid beta-Peptides; Animals; Brain; Cognition Disorders; Diet Thera | 2017 |
Thiamine in septic shock patients with alcohol use disorders: An observational pilot study.
Topics: Aged; Alcoholism; Female; Humans; Male; Middle Aged; Pilot Projects; Practice Patterns, Physicians'; | 2018 |
Prolonged hypotension associated with Wernicke's encephalopathy.
Topics: Aged; Alcoholism; Autonomic Nervous System Diseases; Bradycardia; Dobutamine; Humans; Hypotension; J | 2018 |
Nutritional Status During Inpatient Alcohol Detoxification.
Topics: Adult; Aged; Alcoholism; Avitaminosis; Body Mass Index; Cognition Disorders; Female; Humans; Inpatie | 2018 |
Simultaneous acute Marchiafava-Bignami disease and central pontine myelinolysis: A case report of a challenging diagnosis.
Topics: Adult; Alcoholism; Humans; Magnetic Resonance Imaging; Male; Marchiafava-Bignami Disease; Myelinolys | 2018 |
Thiamine for preventing dementia development among patients with alcohol use disorder: A nationwide population-based cohort study.
Topics: Adult; Aged; Alcoholism; Comorbidity; Dementia; Female; Humans; Male; Middle Aged; Protective Agents | 2019 |
[Wernicke encephalopathy].
Topics: Abducens Nerve Diseases; Alcoholism; Brain; Diagnosis, Differential; Humans; Magnesium Deficiency; P | 2017 |
Thiamine Prescribing and Wernicke's Encephalopathy Risk Factors in Patients With Alcohol Use Disorders at a Psychiatric Hospital.
Topics: Administration, Oral; Adult; Alcoholism; Female; Hospitals, Psychiatric; Humans; Infusions, Parenter | 2018 |
Topics: Abducens Nerve Diseases; Alcoholism; Brain; Diagnosis, Differential; Humans; Magnesium Deficiency; P | 2018 |
[A Reversible Case of Korsakoff Syndrome in an Alcohol Dependent Patient].
Topics: Alcoholism; Ethanol; Folic Acid; Germany; Humans; Korsakoff Syndrome; Male; Middle Aged; Thiamine; V | 2019 |
Wernicke-Korsakoff syndrome: Focus on low-threshold diagnosis and prompt treatment in the primary care setting.
Topics: Alcoholism; Diagnosis, Differential; Dietary Supplements; Folic Acid; Humans; Korsakoff Syndrome; Ma | 2019 |
New-Onset Heart Failure.
Topics: Acidosis; Adult; Alcoholism; Beriberi; Dyspnea; Echocardiography; Edema; Electrocardiography; Heart | 2019 |
Blood thiamine, zinc, selenium, lead and oxidative stress in a population of male and female alcoholics: clinical evidence and gender differences.
Topics: Adult; Aging; Alcoholics; Alcoholism; Female; Humans; Lead; Male; Middle Aged; Oxidative Stress; Sel | 2013 |
[Reports from the Federal Conference of German Psychiatry and Psychotherapy Clinics].
Topics: Alcoholism; Ambulatory Care; Caregivers; Combined Modality Therapy; Ethanol; Germany; Hospitals, Psy | 2013 |
The effect of magnesium administration on erythrocyte transketolase activity in alcoholic patients treated with thiamine.
Topics: Adolescent; Adult; Alcoholism; Drug Therapy, Combination; Erythrocytes; Female; Humans; Infusions, I | 2013 |
Analysis of thiamine transporter genes in sporadic beriberi.
Topics: Adult; Alcoholism; Beriberi; Humans; Male; Membrane Transport Proteins; Mitochondrial Membrane Trans | 2014 |
[Wernicke's encephalopathy induced by the use of diet pills and unbalanced diet].
Topics: Alcoholism; Ataxia; Diet, Reducing; Feeding Behavior; Female; Humans; Oculomotor Nerve Diseases; Thi | 2014 |
Acute reversible Marchiafava-Bignami disease with hypernatremia: a "callosal myelinolysis"?
Topics: Acute Disease; Alcoholism; Combined Modality Therapy; Corpus Callosum; Emergencies; Female; Fluid Th | 2014 |
Prevention of delirium in trauma patients: are we giving thiamine prophylaxis a fair chance?
Topics: Adult; Aged; Alcoholism; Delirium; Diagnostic Tests, Routine; Ethanol; Female; Humans; Injury Severi | 2014 |
Scurvy in an alcoholic patient treated with intravenous vitamins.
Topics: Alcoholism; Ascorbic Acid; Humans; Male; Middle Aged; Niacinamide; Pneumonia, Bacterial; Riboflavin; | 2014 |
Refeeding syndrome is uncommon in alcoholics admitted to a hospital detoxification unit.
Topics: Adult; Aged; Alcoholism; Blood Chemical Analysis; Diagnostic Tests, Routine; Diet; Electrolytes; Fem | 2014 |
Encephalopathy despite thiamine repletion during alcohol withdrawal.
Topics: Alcoholism; Humans; Male; Middle Aged; Niacin; Pellagra; Substance Withdrawal Syndrome; Thiamine; Th | 2014 |
Korsakoff's syndrome is preventable.
Topics: Alcoholism; Humans; Korsakoff Syndrome; Risk Factors; Thiamine | 2014 |
Imaging neuroinflammation? A perspective from MR spectroscopy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Aged, 80 and over; Alcoholism; Antiretroviral Thera | 2014 |
Need for early diagnosis of mental and mobility changes in Wernicke encephalopathy.
Topics: Aged; Alcoholism; Amnesia; Confusion; Early Diagnosis; Gait Ataxia; Humans; Korsakoff Syndrome; Male | 2014 |
Hypomagnesaemia and its potential impact on thiamine utilisation in patients with alcohol misuse at the Alice Springs Hospital.
Topics: Adult; Alcoholism; Cognition Disorders; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; | 2015 |
Risk of thiamine deficiency and Wernicke's encephalopathy after gastrointestinal surgery for cancer.
Topics: Adult; Aged; Alcoholism; Dietary Supplements; Digestive System Surgical Procedures; Female; Gastroin | 2016 |
Shoshin Beriberi With Low Cardiac Output and Hemodynamic Deterioration Treated Dramatically by Thiamine Administration.
Topics: Adult; Alcoholism; Beriberi; Cardiac Output, Low; Diagnosis, Differential; Disease Management; Extra | 2015 |
Wernicke encephalopathy and pellagra in an alcoholic and malnourished patient.
Topics: Alcoholism; Confusion; Dementia; Dermatitis; Diarrhea; Humans; Magnetic Resonance Imaging; Male; Mid | 2015 |
The Long-Term Cost to the UK NHS and Social Services of Different Durations of IV Thiamine (Vitamin B1) for Chronic Alcohol Misusers with Symptoms of Wernicke's Encephalopathy Presenting at the Emergency Department.
Topics: Adult; Alcoholism; Emergency Service, Hospital; Humans; Male; Prospective Studies; Social Work; Stat | 2016 |
Striking Central Pontine Myelinolysis in a Patient With Alcohol Dependence Syndrome Without Hyponatremia.
Topics: Aged; Alcoholism; Brain; Humans; Hyponatremia; Magnetic Resonance Imaging; Male; Myelinolysis, Centr | 2016 |
A case of methemoglobinemia after ingestion of a chlorhexidine in alcohol solution in an alcohol-dependent patient.
Topics: Administration, Oral; Alcoholism; Chlorhexidine; Cyanosis; Diazepam; Dose-Response Relationship, Dru | 2016 |
[Marchiafava-Bignami disease (Case-report)].
Topics: Alcoholism; Corpus Callosum; Humans; Magnetic Resonance Imaging; Marchiafava-Bignami Disease; Thiami | 2016 |
Mutism Caused by Severe Demyelination in a Patient With Marchiafava-Bignami Disease.
Topics: Alcoholism; Female; Gastric Bypass; Glucose; Humans; Magnetic Resonance Imaging; Marchiafava-Bignami | 2016 |
Reversal of refractory severe lactic acidosis by thiamine replacement.
Topics: Acidosis, Lactic; Acute Disease; Administration, Intravenous; Adult; Aged; Alcoholism; Anti-Bacteria | 2017 |
Alcohol use, thiamine deficiency, and cognitive impairment.
Topics: Aged; Alcohol Drinking; Alcoholism; Australia; Bread; Food, Fortified; Humans; Korsakoff Syndrome; T | 2008 |
Mammillothalamic functional connectivity and memory function in Wernicke's encephalopathy.
Topics: Adult; Alcoholism; Anterior Thalamic Nuclei; Brain; Case-Control Studies; Humans; Magnetic Resonance | 2009 |
Marchiafava-Bignami disease.
Topics: Adult; Aged; Alcoholism; Corpus Callosum; Humans; Magnetic Resonance Imaging; Male; Marchiafava-Bign | 2008 |
[Gayet-Wernicke's encephalopathy. A study of 13 cases observed in a refugee population hospitalized at the Conakry Teaching Hospital].
Topics: Alcoholism; Confusion; Guinea; HIV Infections; Humans; Refugees; Survival Rate; Survivors; Thiamine; | 2008 |
Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase.
Topics: Alcoholism; Amprolium; Animals; Cell Death; Cells, Cultured; Central Nervous System Depressants; Coc | 2009 |
Morel's laminar sclerosis showing apraxia of speech: distribution of cortical lesions in an autopsy case.
Topics: Alcoholism; Apraxias; Autopsy; Brain; Brain Diseases; Chronic Disease; Fatal Outcome; Humans; Male; | 2010 |
Wernicke encephalopathy in alcoholics with diabetic ketoacidosis.
Topics: Aged; Alcoholism; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Humans; Insulin; Magnetic Resona | 2009 |
A multi-centre survey of inpatient pharmacological management strategies for alcohol withdrawal.
Topics: Alcoholism; Guideline Adherence; Health Care Surveys; Hospitalization; Humans; Hypnotics and Sedativ | 2009 |
[Confusion, gait ataxia and ophthalmoplegia in a patient with chronic alcohol consumption].
Topics: Aged; Alcoholism; Humans; Magnetic Resonance Imaging; Male; Malnutrition; Thiamine; Wernicke Encepha | 2010 |
Measurement of serum, liver, and brain cytokine induction, thiamine levels, and hepatopathology in rats exposed to a 4-day alcohol binge protocol.
Topics: Alcoholism; Alkaline Phosphatase; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Chemical | 2010 |
Signs of preclinical Wernicke's encephalopathy and thiamine levels as predictors of neuropsychological deficits in alcoholism without Korsakoff's syndrome.
Topics: Adult; Alcohol Amnestic Disorder; Alcoholism; Analysis of Variance; Cognition Disorders; Female; Fol | 2011 |
Timing of efficacy of thiamine in Wernicke's disease in alcoholics at risk.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholics; Alcoholism; Health Surveys; Humans; Middle Aged; Pri | 2011 |
Problem drinking--management in general practice.
Topics: Alcohol Withdrawal Delirium; Alcohol-Related Disorders; Alcoholism; Counseling; General Practice; Hu | 2011 |
Harmful drinking and alcohol dependence: advice from recent NICE guidelines.
Topics: Alcohol Deterrents; Alcohol-Related Disorders; Alcoholism; Humans; Mental Disorders; Naloxone; Patie | 2011 |
Auto-antibody-negative limbic-like encephalitis as the first manifestation of Neurosyphilis.
Topics: Aged; Alcoholism; Anticonvulsants; Autoantibodies; Cognition Disorders; Epilepsy, Generalized; Human | 2013 |
Marchiafava-Bignami disease: a case report.
Topics: Adult; Alcoholism; Brain Edema; Corpus Callosum; Demyelinating Diseases; Humans; Magnetic Resonance | 2002 |
Shoshin beriberi with vasospastic angina pectoris possible mechanism of mid-ventricular obstruction: possible mechanism of mid-ventricular obstruction.
Topics: Aged; Alcoholism; Angina Pectoris; Beriberi; Catecholamines; Coronary Vasospasm; Echocardiography; H | 2002 |
Individual susceptibility to Wernicke-Korsakoff syndrome and alcoholism-induced cognitive deficit: impaired thiamine utilization found in alcoholics and alcohol abusers.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Brain Damage, Chronic; Cognition Disorders; Genetic Predi | 2002 |
Diffusion abnormalities and Wernicke encephalopathy.
Topics: Adult; Aged; Alcoholism; Brain Edema; Diffusion Magnetic Resonance Imaging; Female; Gastrectomy; Hum | 2003 |
[Can alcoholic withdrawal delirium be prevented?].
Topics: Alcohol Withdrawal Delirium; Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; | 2003 |
Simultaneous liquid chromatographic assessment of thiamine, thiamine monophosphate and thiamine diphosphate in human erythrocytes: a study on alcoholics.
Topics: Adolescent; Alcoholism; Case-Control Studies; Erythrocytes; Female; Humans; Male; Middle Aged; Repro | 2003 |
[Aneurin shock, incompatibility reaction of anaphylactic type in a senile chronic alcoholic woman].
Topics: Alcoholism; Female; Humans; Hypersensitivity; Immune System Diseases; Shock; Thiamine | 1952 |
The effect of caloric restriction and thiamin deficiency on the voluntary consumption of alcohol by rats.
Topics: Alcoholism; Animals; Caloric Restriction; Diet; Ethanol; Rats; Thiamine; Thiamine Deficiency; Vitami | 1953 |
DIETARY intake and alcoholism.
Topics: Alcoholism; Diet; Ethanol; Humans; Thiamine; Vitamin B Deficiency | 1954 |
The treatment of alcoholics in an outpatient clinic with adrenal cortex hormones and vitamin B1.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Alcoholics; Alcoholism; Ambulatory Care Facilities; Humans; | 1954 |
[Importance of large doses of vitamin B1 in the treatment of alcoholic encephalopathies; 3 case reports].
Topics: Alcohol-Related Disorders; Alcoholism; Humans; Psychotic Disorders; Syndrome; Thiamine; Vitamin B De | 1957 |
[Alcoholic myocardia and alcoholic beri-beri. The 2 stages of alcoholic cardiac insufficiency. The notion of peripheral asystole].
Topics: Alcoholism; Beriberi; Heart Arrest; Heart Failure; Humans; Myocardium; Thiamine | 1963 |
[The treatment of brain diseases and neurologic complications of chronic alcoholism by the combination of strychnal and massive doses of vitamin B1].
Topics: Alcoholism; Brain Diseases; Humans; Nervous System Diseases; Neurologic Manifestations; Strychnine; | 1963 |
VITAMIN UNRESPONSIVENESS. PROGRESSION OF CLASSIC SIGNS OF NEUROPATHY AND PELLAGRA DURING THERAPY.
Topics: Alcoholism; Avitaminosis; Diarrhea; Humans; Hyperesthesia; Liver Cirrhosis; Movement Disorders; Neur | 1963 |
MANAGEMENT OF ALCOHOLISM WITH PROMAZINE.
Topics: Alcoholism; Disease Management; Promazine; Thiamine; Toxicology | 1964 |
EFFECT OF HEPATIC DISEASE ON LIVER B-COMPLEX VITAMIN TITERS.
Topics: Alcoholism; Biological Assay; Biopsy; Biotin; Fatty Liver; Folic Acid; Humans; Liver; Liver Cirrhosi | 1964 |
[DEFICIENCY ALCOHOLIC ENCEPHALOPATHY AND MAGNESIUM: GAYET-WERNICKE SYNDROME].
Topics: Alcohol Amnestic Disorder; Alcoholism; Diagnosis; Humans; Magnesium; Magnesium Deficiency; Thiamine; | 1964 |
[ON THE HEART OF THE ALCOHOLIC, THE SO-CALLED OCCIDENTAL BERIBERI HEART].
Topics: Alcoholism; Beriberi; Digitalis Glycosides; Heart; Heart Diseases; Heart Failure; Strophanthins; Thi | 1964 |
PERIPHERAL NEUROPATHY OF THE ALCOHOLIC: I, AETIOLOGICAL ROLE OF ANEURIN AND OTHER B-COMPLEX VITAMINS.
Topics: Alcoholism; Biotin; Blood Chemical Analysis; Corrinoids; Folic Acid; Hematinics; Humans; Niacin; Nic | 1964 |
[MARCHIAFAVA-BIGNAMI SYNDROME IN EXPERIMENTAL CHRONIC ALCOHOLISM].
Topics: Alcoholic Intoxication; Alcoholism; Brain Diseases; Corpus Callosum; Dogs; Marchiafava-Bignami Disea | 1964 |
[A MULTIPLE TISSUE EXTRACT (PAT) AS BASIC MEDICATION FOR ALCOHOLIC DETOXICATION CURES].
Topics: Alcoholism; Ascorbic Acid; Brain; Corrinoids; Drug Therapy; Humans; Liver Extracts; Mental Disorders | 1964 |
[CLINICAL OBSERVATIONS ON THE SUBJECT OF VITAMIN THERAPY].
Topics: Alcoholism; Drug Therapy; Humans; Kidney Diseases; Liver Cirrhosis; Neoplasms; Pyridoxine; Thiamine; | 1964 |
TOXIC EPIDERMAL NECROLYSIS.
Topics: Alcoholism; Anti-Bacterial Agents; Chloramphenicol; Chlorpromazine; Drug Eruptions; Drug Therapy; Hu | 1965 |
BLOOD PYRUVIC AND ALPHA-KETOGLUTARIC ACIDS IN THIAMINE DEFICIENCY.
Topics: Alcoholism; Blood; Chromatography; Drug Therapy; Glucose Tolerance Test; Humans; Ketoglutaric Acids; | 1965 |
B-COMPLEX VITAMINS IN LIVER DISEASE OF THE ALCOHOLIC.
Topics: Alcoholism; Autoradiography; Biopsy; Biotin; Blood Chemical Analysis; DNA; Drug Therapy; Fatty Liver | 1965 |
Wernicke's encephalopathy after glucose infusion.
Topics: Alcoholism; Brain; Coma; Confusion; Diagnostic Errors; Fatal Outcome; gamma-Glutamyltransferase; Glu | 2004 |
Thiamin therapy in neuropsychiatry.
Topics: Alcoholism; Electroconvulsive Therapy; Humans; Neuritis; Neuropsychiatry; Psychotherapy; Psychotic D | 1952 |
Brain SPECT findings in Wernicke's encephalopathy.
Topics: Adult; Alcoholism; Brain; Humans; Magnetic Resonance Imaging; Male; Thiamine; Tomography, Emission-C | 2004 |
Occidental beriberi and sudden death.
Topics: Adult; Alcoholism; Beriberi; Death, Sudden; Fatal Outcome; Humans; Male; Myocardium; Thiamine; Thiam | 2004 |
Ketosis and cardiac failure: common signs of a single condition.
Topics: Alcoholism; Beriberi; Cachexia; Diagnosis, Differential; Emergency Medical Services; Female; Heart F | 2004 |
Preliminary investigation of thiamine and alcohol intake in clinical and healthy samples.
Topics: Adult; Alcoholism; Female; Health Status; Hospitalization; Humans; Male; Thiamine | 2004 |
Wernicke encephalopathy.
Topics: Aged; Alcoholism; Female; Gait Disorders, Neurologic; Humans; Magnetic Resonance Imaging; Nystagmus, | 2004 |
[Rapid improvement of callosal edema by thiamine administration in Marchiafava-Bignami disease: a case report].
Topics: Alcoholism; Brain Edema; Corpus Callosum; Demyelinating Diseases; Humans; Magnetic Resonance Imaging | 2004 |
Images in clinical medicine. Marchiafava-Bignami disease.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Brain; Corpus Callosum; Demyelinating Disease | 2004 |
Alcoholic ketoacidosis associated with multiple complications: report of 3 cases.
Topics: Acidosis; Alcoholism; Dehydration; Diabetic Ketoacidosis; Female; Glucose; Humans; Insulin; Ketone B | 2004 |
A patient with severe lactic acidosis and rapidly evolving multiple organ failure: a case of shoshin beri-beri.
Topics: Acidosis, Lactic; Alcoholism; Beriberi; Humans; Male; Middle Aged; Multiple Organ Failure; Thiamine | 2005 |
Diffusion-weighted magnetic resonance imaging in Marchiafava-Bignami disease: follow-up studies.
Topics: Adult; Alcoholism; Anti-Bacterial Agents; Demyelinating Diseases; Diffusion Magnetic Resonance Imagi | 2005 |
[Alcohol dependence and depressive disorders in the course of opiate dependence].
Topics: Adult; Alcoholism; Antipsychotic Agents; Benzodiazepines; Combined Modality Therapy; Depressive Diso | 2005 |
Development and resolution of brain lesions caused by pyrithiamine- and dietary-induced thiamine deficiency and alcohol exposure in the alcohol-preferring rat: a longitudinal magnetic resonance imaging and spectroscopy study.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Antimetabolites; Biomarkers; Brain; | 2007 |
[A man with the combination of dry and wet beriberi].
Topics: Adult; Alcoholic Neuropathy; Alcoholism; Beriberi; Cardiomyopathy, Alcoholic; Diagnosis, Differentia | 2006 |
[Marchiafava-Bignami disease].
Topics: Adult; Alcohol-Induced Disorders, Nervous System; Alcoholism; Brain Diseases; Corpus Callosum; Demye | 2006 |
The effect of acamprosate on alcohol and food craving in patients with alcohol dependence.
Topics: Acamprosate; Adult; Alcohol Deterrents; Alcoholism; Body Mass Index; Cognitive Behavioral Therapy; C | 2008 |
Properties of thiamine transport in isolated perfused hearts of chronically alcoholic guinea pigs.
Topics: Alcoholism; Animals; Biological Transport, Active; Carbon Radioisotopes; Carbonyl Cyanide m-Chloroph | 2008 |
Myocardopathy, alcohol, and pericardial effusion.
Topics: Alcoholism; Beer; Cardiac Catheterization; Heart Failure; Humans; Male; Middle Aged; Pericardial Eff | 1967 |
Wernicke's encephalopathy: studies on blood pyruvic acid and alpha-ketoglutaric acids.
Topics: Adult; Alcoholism; Brain Diseases; Chromatography; Glucose; Humans; Ketoglutaric Acids; Male; Middle | 1967 |
Red blood cell-transketolase activity in malnourished alcoholics with cirrhosis.
Topics: Adult; Alcoholism; Deficiency Diseases; Erythrocytes; Female; Humans; Liver Cirrhosis; Male; Middle | 1967 |
Effect of long-continued alcohol consumption on the thiamine content of rat tissues.
Topics: Alcoholism; Animals; Brain; Female; Heart; Humans; Liver; Male; Muscles; Myocardium; Rats; Thiamine | 1967 |
Possible relationships between thiamine, carnitine, polyunsaturated fatty acids and the neurotoxicity of alcohol.
Topics: Alcoholism; Animals; Carnitine; Ethanol; Fatty Acids, Unsaturated; gamma-Linolenic Acid; Humans; Lin | 1984 |
Cardiovascular beriberi.
Topics: Alcoholism; Beriberi; Cardiomyopathies; Ethanol; Heart Failure; Hemodynamics; Humans; Thiamine; Thia | 1982 |
The severe lacticacidosis of thiamine deficiency: acute pernicious or fulminating beriberi.
Topics: Acidosis; Acute Disease; Adult; Alcoholism; Beriberi; Female; Humans; Lactates; Male; Middle Aged; T | 1984 |
Peripheral nerve conduction, visual evoked potentials and vitamin B1 serum level in chronic alcoholics.
Topics: Alcoholism; Evoked Potentials, Visual; Female; Humans; Male; Middle Aged; Neural Conduction; Periphe | 1983 |
Vitamin supplement to alcoholic beverages.
Topics: Alcoholic Beverages; Alcoholism; Humans; Peripheral Nervous System Diseases; Thiamine | 1984 |
Recognition and treatment of acute alcohol withdrawal syndromes.
Topics: Acute Disease; Alcohol Withdrawal Delirium; Alcoholism; Benzodiazepines; Chloral Hydrate; Ethanol; F | 1984 |
Alcohol and thiamine metabolism.
Topics: Alcoholism; Ethanol; Humans; Intestinal Absorption; Thiamine; Thiamine Deficiency | 1983 |
Wernicke's encephalopathy induced by tolazamide.
Topics: Adult; Alcoholism; Diabetic Ketoacidosis; Humans; Male; Thiamine; Tolazamide; Wernicke Encephalopath | 1983 |
Thiamin Metabolism in the rat during long-term alcohol administration. 1. Communication: ethanol induced changes at optimal thiamin supply.
Topics: Alcoholism; Animals; Humans; Intestinal Absorption; Isoenzymes; Liver; Male; Myocardium; Rats; Rats, | 1982 |
Shoshin or acute pernicious beri beri.
Topics: Adult; Alcoholism; Beriberi; Cardiac Output; Cardiac Output, Low; Cardiomyopathies; Humans; Male; Th | 1981 |
Accidental hypothermia: a report of 22 cases and review of the literature.
Topics: Adult; Aged; Alcoholism; Arrhythmias, Cardiac; Body Temperature; Critical Care; Female; Glucose; Hot | 1982 |
Thiamin monophosphate in the CSF of patients with amyotrophic lateral sclerosis.
Topics: Adult; Aged; Alcoholism; Amyotrophic Lateral Sclerosis; Blood Proteins; Female; Humans; Male; Middle | 1982 |
Excessive beer consumption and beri-beri.
Topics: Adult; Alcoholism; Beriberi; Feeding Behavior; Heart Failure; Humans; Male; Scotland; Tachycardia; T | 1982 |
Blood vitamin status (B1, B2, B6, folic acid and B12) in patients with alcoholic liver disease.
Topics: Adult; Alcoholism; Folic Acid; Hepatitis; Humans; Liver Cirrhosis, Alcoholic; Liver Diseases; Middle | 1982 |
Vitamin profile in rats fed stock or liquid ethanolic diets.
Topics: Alcoholism; Animals; Biotin; Ethanol; Folic Acid; Humans; Liver; Male; Nicotinic Acids; Pantothenic | 1980 |
The adequacy of thiamine in liquid diets used in animal models of alcoholism.
Topics: Alcoholism; Animals; Brain; Disease Models, Animal; Ethanol; Food, Formulated; Humans; Male; Nutriti | 1980 |
[A little-known alcoholic emergency: shoshin beriberi].
Topics: Alcoholism; Beriberi; Diagnosis, Differential; Humans; Shock, Cardiogenic; Thiamine | 1981 |
Swellengrebel lecture. Beriberi.
Topics: Adult; Alcoholism; Beriberi; Electrocardiography; Heart Failure; Humans; Male; Radiography, Thoracic | 1980 |
Effect of peroral thiamine treatment on thiamine contents and transketolase activity of red blood cells in alcoholic patients.
Topics: Adult; Alcoholism; Erythrocytes; Female; Humans; Male; Middle Aged; Thiamine; Thiamine Deficiency; T | 1981 |
Plasma thiamin pyrophosphate and erythrocyte transketolase in chronic alcoholism.
Topics: Alcoholism; Erythrocytes; Female; Humans; Male; Reference Values; Thiamine; Thiamine Pyrophosphate; | 1981 |
Vitamin utilization status in chronic alcoholics.
Topics: Adult; Aged; Alcoholism; Erythrocytes; Female; Glutathione Reductase; Humans; Male; Middle Aged; Pyr | 1981 |
[The alcoholic Wernicke's encephalopathy--observation of clinical course and responsiveness to thiamine in five cases (author's transl)].
Topics: Adult; Aged; Alcoholism; Humans; Male; Middle Aged; Oculomotor Nerve; Thiamine; Wernicke Encephalopa | 1981 |
[Levels of vitamin B1 and B12 and of folic acid in alcoholic polyneuropathy (author's transl)].
Topics: Adult; Alcoholism; Folic Acid; Humans; Hypesthesia; Muscle Cramp; Neural Conduction; Polyneuropathie | 1981 |
Relation between chronic alcoholism, drug addiction and nutrition with special reference to the thiamine status.
Topics: Alcoholism; Dose-Response Relationship, Drug; Humans; Nutritional Physiological Phenomena; Substance | 1981 |
[Trace elements and vitamins A, B1 and B2 in the serum of alcoholics].
Topics: Alcoholism; Humans; Male; Riboflavin; Thiamine; Trace Elements; Vitamin A; Vitamins | 1981 |
Monophosphate, the only phosphoric ester of thiamin in the cerebro-spinal fluid.
Topics: Alcoholism; Animals; Cats; Dogs; Drug Stability; Electrophoresis; Fluorometry; Humans; Rabbits; Swin | 1981 |
Blood thiamine and blood folate levels. A comparative study in control, alcoholic and folate-deficient subjects.
Topics: Adolescent; Adult; Aged; Alcoholism; Biological Assay; Erythrocytes; Female; Folic Acid; Folic Acid | 1981 |
Effect of ethanol ingestion on thiamine metabolism: clinical and experimental studies.
Topics: Adult; Aged; Alcoholism; Animals; Body Weight; Brain; Brain Chemistry; Cerebellum; Corpus Striatum; | 1981 |
Blood vitamin status in chronic alcoholics after a single dose of polyvitamin. A preliminary report.
Topics: Adult; Alcoholism; Avitaminosis; Enzyme Activation; Female; Humans; Male; Middle Aged; Pyridoxine; R | 1981 |
[Thiamine and thiamine deficiency in alcoholism].
Topics: Alcoholism; Brain Chemistry; Humans; Thiamine; Thiamine Deficiency | 1980 |
Clinical thiamine deficiency in Australia: the size of the problem and approaches to prevention.
Topics: Alcoholic Beverages; Alcoholism; Australia; Flour; Food, Fortified; Health Education; Humans; Thiami | 1980 |
Chlormethiazole and utilization of vitamin B1 in chronic alcoholics.
Topics: Adult; Aged; Alcoholism; Chlormethiazole; Enzyme Activation; Erythrocytes; Female; Humans; Male; Mid | 1980 |
Transketolase-TPP-effect in chronic alcoholics with various degrees of liver cirrhosis.
Topics: Alcoholism; Female; Humans; Liver Cirrhosis, Alcoholic; Male; Thiamine; Thiamine Pyrophosphate; Tran | 1980 |
Treatment of alcoholism: the role of the primary care physician.
Topics: Alcoholism; Anticonvulsants; Follow-Up Studies; Humans; Male; Middle Aged; Physicians, Family; Thiam | 1981 |
Reduced activities of thiamine-dependent enzymes in brains of alcoholics in the absence of Wernicke's encephalopathy.
Topics: Aged; Alcoholism; Brain; Female; Humans; Ketoglutarate Dehydrogenase Complex; Male; Middle Aged; Pyr | 1995 |
Acute pernicious or fulminating beriberi heart disease. A report of 6 patients.
Topics: Acute Disease; Adult; Alcoholism; Beriberi; Diagnosis, Differential; Female; Heart Diseases; Humans; | 1995 |
Thiamine in Wernicke's syndrome--how much and how long?
Topics: Adult; Alcoholism; Dose-Response Relationship, Drug; Female; Humans; Thiamine; Thiamine Deficiency; | 1995 |
Reversible neurological deficits in a chronic alcohol abuser: a case report of Wernicke's encephalopathy.
Topics: Adult; Alcoholism; Ataxia; Confusion; Diagnosis, Differential; Emergency Service, Hospital; Female; | 1994 |
Thiamin and thiamin phosphate ester deficiency assessed by high performance liquid chromatography in four clinical cases of Wernicke encephalopathy.
Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Blood-Brain Barrier; Brain; Female; Humans; Ma | 1993 |
Wernicke-Korsakoff syndrome in Sydney hospitals: before and after thiamine enrichment of flour.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Amnestic Disorder; Alcoholism; Bread; Female; Food, Fortifie | 1995 |
[Failure in self care and heart failure, thiamine deficiency in geriatric patients].
Topics: Aged; Alcoholism; Female; Heart Failure; Humans; Male; Nutrition Disorders; Self Care; Thiamine; Thi | 1996 |
Can megadoses of thiamine prevent ethanol-induced damages of rat hippocampal CA1 pyramidal neurones?
Topics: Alcoholism; Animals; Central Nervous System Depressants; Eating; Ethanol; Hippocampus; Male; Pyramid | 1996 |
Nutritional deficiencies in chronic alcoholics: relation to dietary intake and alcohol consumption.
Topics: Adult; Alcohol Drinking; Alcoholism; Avitaminosis; Body Height; Body Mass Index; Body Weight; Diet; | 1997 |
Neurogenic impotence and lower urinary tract symptoms due to vitamin B1 deficiency in chronic alcoholism.
Topics: Aged; Alcoholism; Erectile Dysfunction; Humans; Male; Thiamine; Thiamine Deficiency; Urination Disor | 1997 |
[Case of Wernicke's encephalopathy complicated with Marchiafava-Bignami syndrome].
Topics: Alcoholism; Anti-Inflammatory Agents; Corpus Callosum; Demyelinating Diseases; Humans; Male; Methylp | 1997 |
Prevalence of Wernicke-Korsakoff syndrome in Australia: has thiamine fortification made a difference?
Topics: Adolescent; Adult; Aged; Alcoholism; Australia; Autopsy; Beer; Brain; Bread; Female; Food, Fortified | 1998 |
Lactic acidosis caused by thiamine deficiency in a pregnant alcoholic patient.
Topics: Acidosis, Lactic; Adult; Alcoholism; Diagnosis, Differential; Female; Humans; Pregnancy; Pregnancy C | 1999 |
A 3 year case study of alcohol related psychotic disorders at Hospital Seremban.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Diazepam; Drug Therapy, Combination; F | 1998 |
[Korsakoff amnesia syndrome].
Topics: Aged; Alcoholism; Female; Humans; Incidence; Korsakoff Syndrome; Male; Memory; Mental Processes; Mid | 2000 |
Thiamine-responsive acute neurological disorders in nonalcoholic patients.
Topics: Acute Disease; Adolescent; Adult; Alcoholism; Female; Humans; Male; Middle Aged; Thiamine; Wernicke | 2001 |
[Unusual MR findings of Wernicke encephalopathy with cortical involvement].
Topics: Alcoholism; Cerebral Cortex; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Motor Cortex; Qu | 2001 |
Putting thiamine in beer: comments on Truswell's editorial.
Topics: Aged; Aged, 80 and over; Alcoholism; Beer; Food, Fortified; Humans; Intestinal Absorption; Thiamine; | 2000 |
[Shoshin beriberi: myth or reality?].
Topics: Acidosis; Adult; Alcoholism; Beriberi; Diagnosis, Differential; Heart Arrest; Humans; Thiamine | 2001 |
[Chronic alcohol abuse. Benfotiamine in alcohol damage is a must].
Topics: Alcoholic Neuropathy; Alcoholism; Humans; Thiamine; Treatment Outcome; Workplace | 2001 |
Wernicke's encephalopathy in a non-alcoholic man: case report and brief review.
Topics: Adult; Alcoholism; Humans; Male; Thiamine; Thiamine Deficiency; Wernicke Encephalopathy | 2001 |
Wernicke encephalopathy in nonalcoholic patients.
Topics: Adult; Aged; Alcoholism; Brain; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Retro | 2002 |
Lacticacidosis in alcoholic beri-beri.
Topics: Acidosis; Alcoholism; Beriberi; Humans; Hydroxybutyrates; Lactates; Thiamine | 1978 |
Prevention of the Wernicke-Korsakoff syndrome: a cost-benefit analysis.
Topics: Alcohol Amnestic Disorder; Alcoholic Beverages; Alcoholism; Cost-Benefit Analysis; Food, Fortified; | 1978 |
Prevention that pays for itself.
Topics: Alcohol Amnestic Disorder; Alcoholic Beverages; Alcoholism; Cost-Benefit Analysis; Food, Fortified; | 1978 |
Primary alcoholic heart disease.
Topics: Alcoholism; Cardiomegaly; Cell Membrane Permeability; Diagnosis, Differential; Diet Therapy; Digital | 1975 |
Thiamine status in alcoholism.
Topics: Alcoholism; Erythrocytes; Female; Humans; Male; Middle Aged; Thiamine; Thiamine Deficiency; Thiamine | 1977 |
The value of thiamine replacement in chronic alcoholism: a reminder.
Topics: Alcoholism; Humans; Nervous System Diseases; Thiamine; Thiamine Deficiency | 1979 |
[Therapy of alcoholism. The use of thiamine, ATP and magnesium and the control of clomethiazole sympathetic blockade (author's transl)].
Topics: Adenosine Triphosphate; Adult; Alcoholism; Chlormethiazole; Coma; Dextrans; Female; Humans; Magnesiu | 1978 |
Wet beri-beri in an alcoholic after gastrectomy.
Topics: Alcoholism; Beriberi; Gastrectomy; Heart Failure; Humans; Male; Middle Aged; Thiamine | 1979 |
The significance of the serum levels of vitamin B-1 and magnesium in delirium tremens and alcoholism.
Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Humans; Magnesium; Magnesium Deficiency; Middl | 1979 |
Treatment of alcoholic lactic acidosis.
Topics: Acidosis; Alcoholism; Humans; Lactates; Native Hawaiian or Other Pacific Islander; Thiamine; Thiamin | 1979 |
[Hypoglycemia and acidosis after alcohol drinking].
Topics: Acidosis; Alcoholism; Body Weight; Glucose; Humans; Hypoglycemia; Thiamine; Thiamine Deficiency | 1977 |
The effects of chronic ethanol consumption on goniomitosis in the rat.
Topics: Alcoholism; Animals; Chromosome Aberrations; Diet; Humans; Male; Mitosis; Rats; Spermatogonia; Sperm | 1977 |
Effect of chronic ethanol administration on thiamin metabolism in the rat.
Topics: Alcoholism; Animals; Energy Intake; Feces; Humans; Male; Rats; Thiamine; Time Factors; Tissue Distri | 1977 |
[Treatment of drug-dependent alcoholics in a non-psychiatric medical milieu. Withdrawal treatment technic].
Topics: Alcoholism; Diazepam; Humans; Hypnotics and Sedatives; Nutritional Physiological Phenomena; Thiamine | 1978 |
Thermolability in Wernicke's encephalopathy.
Topics: Alcoholism; Body Temperature Regulation; Humans; Male; Middle Aged; Thiamine; Wernicke Encephalopath | 1978 |
Alcohol intoxication and the alcohol withdrawal syndrome.
Topics: Alcoholic Intoxication; Alcoholism; Benzodiazepines; Chlordiazepoxide; Hallucinations; Humans; Pheny | 1978 |
Pellagra: an analysis of 18 patients and a review of the literature.
Topics: Adult; Aged; Alcoholism; Brain Diseases; Dermatitis; Diarrhea; Female; Humans; Male; Middle Aged; Ne | 1977 |
[Use of thiamine before and after surgical intervention in chronic alcoholism].
Topics: Alcoholism; Humans; Thiamine; Time Factors | 1977 |
[Clinical diagnosis and course of wernicke's encephalopathy (author's transl)].
Topics: Acute Disease; Adult; Aged; Alcoholism; Blepharoptosis; Female; Humans; Male; Middle Aged; Ophthalmo | 1977 |
Vitamin B1, B2 and B6 status in chronic alcoholics.
Topics: Adult; Alcoholism; Female; Humans; Male; Middle Aged; Pyridoxine; Riboflavin; Risk; Thiamine; Vitami | 1977 |
Early signs of thiamine deficiency.
Topics: Adult; Alcoholism; Chronic Disease; Clinical Enzyme Tests; Erythrocytes; Humans; Male; Military Medi | 1976 |
Early signs of thiamine deficiency.
Topics: Adult; Alcoholism; Clinical Enzyme Tests; Humans; Thiamine; Thiamine Deficiency; Thiamine Pyrophosph | 1976 |
Absorption, utilization and clinical effectiveness of allithiamines compared to water-soluble thiamines.
Topics: Adult; Alcoholism; Avitaminosis; Clinical Enzyme Tests; Humans; Liver Diseases; Male; Middle Aged; T | 1976 |
[Alcoholism and nutritional state (proceedings)].
Topics: Alcoholism; Avitaminosis; Clinical Enzyme Tests; Humans; Iron; Magnesium; Magnesium Deficiency; Nutr | 1976 |
[Vitamin B 1 deficiency in chronic alcoholics and its clinical correlation].
Topics: Adult; Aged; Alcoholism; Anemia; Avitaminosis; Erythrocytes; Female; Humans; Male; Middle Aged; Thia | 1976 |
Pyridoxine deficiency in severe liver disease [proceedings].
Topics: Alcoholism; Ascorbic Acid; Ascorbic Acid Deficiency; Avitaminosis; Humans; Liver Cirrhosis; Pyridoxa | 1976 |
Intestinal function in chronic alcoholism.
Topics: Alcohol Oxidoreductases; Alcoholism; Chronic Disease; Diet Therapy; Digestive System; Dose-Response | 1975 |
Protective action of ascorbic acid and sulfur compounds against acetaldehyde toxicity: implications in alcoholism and smoking.
Topics: Acetaldehyde; Acetylcysteine; Alcoholism; Anesthetics; Animals; Ascorbic Acid; Cysteine; Humans; Let | 1975 |
Reversible corticospinal abnormality in the alcoholic.
Topics: Adult; Alcoholism; Demyelinating Diseases; Female; Humans; Male; Middle Aged; Paralysis; Pons; Refle | 1975 |
Blood and serum thiamin and thiamin phosphate esters concentrations in patients with alcohol dependence syndrome before and after thiamin treatment.
Topics: Adult; Alcoholism; Chromatography, High Pressure Liquid; Female; Humans; Liver Diseases, Alcoholic; | 1992 |
Effect of ethanol on the in vivo kinetics of thiamine phosphorylation and dephosphorylation in different organs of rat--II. Acute effects.
Topics: Alcohol Drinking; Alcoholism; Animals; Brain; Male; Peripheral Nerves; Phosphoric Monoester Hydrolas | 1992 |
Increased central immunoreactive beta-endorphin content in patients with Wernicke-Korsakoff syndrome and in alcoholics.
Topics: Adrenocorticotropic Hormone; Aged; Alcohol Amnestic Disorder; Alcoholism; alpha-MSH; Autopsy; beta-E | 1991 |
[Thiamine deficiency and brain atrophy in alcoholic patients].
Topics: Adult; Alcoholism; Atrophy; Brain; Female; Follow-Up Studies; gamma-Glutamyltransferase; Humans; Mal | 1991 |
The effect of ethanol and other alcohols on morphometric parameters of rat small intestinal microvillous vesicles.
Topics: Alcoholism; Alcohols; Animals; Epithelium; Ethanol; Female; Image Processing, Computer-Assisted; Int | 1991 |
Wernicke's encephalopathy and alcohol-related disease.
Topics: Adult; Alcoholism; Brain; Female; Humans; Incidence; Male; Middle Aged; Thiamine; Wernicke Encephalo | 1991 |
In thiamine deficiency, activation of erythrocyte transketolase by thiamine in vivo exceeds activation by cofactor in vitro.
Topics: Alcoholism; Apoenzymes; Erythrocytes; Humans; In Vitro Techniques; Regression Analysis; Retrospectiv | 1991 |
Thiamine in our bread and wine.
Topics: Alcohol Amnestic Disorder; Alcoholism; Humans; Thiamine; Wernicke Encephalopathy | 1991 |
Effect of ethanol administration on the in vivo kinetics of thiamine phosphorylation and dephosphorylation in different organs. I. Chronic effects.
Topics: Alcoholism; Animals; Intestinal Mucosa; Kidney; Liver; Male; Myocardium; Rats; Rats, Inbred Strains; | 1991 |
[Cerebral beriberi with ophthalmoplegia as the leading symptom in an alcoholic patient].
Topics: Alcoholism; Beriberi; Female; Humans; Middle Aged; Ophthalmoplegia; Thiamine; Thiamine Deficiency; W | 1991 |
Effects of acute and chronic ethanol administration on thiamine metabolizing enzymes in some brain areas and in other organs of the rat.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Arousal; Brain; Energy Intake; Male; Phosphoric Monoest | 1990 |
Blood thiamine and thiamine phosphate concentrations in excessive drinkers with or without peripheral neuropathy.
Topics: Adult; Alcoholism; Female; Humans; Liver Function Tests; Male; Neurologic Examination; Peripheral Ne | 1990 |
Abnormalities of peripheral nerve conduction in relation to thiamine status in alcoholic patients.
Topics: Adult; Aged; Alcoholism; Electromyography; Evoked Potentials; Humans; Middle Aged; Neural Conduction | 1991 |
Thiamine in our bread and wine?
Topics: Alcohol Amnestic Disorder; Alcoholic Beverages; Alcoholism; Cost Control; Food, Fortified; Humans; T | 1990 |
[Strict abstinence].
Topics: Alcoholism; Humans; Temperance; Thiamine; Thiamine Deficiency | 1989 |
[Cognitive deficits, vitamin status and controlled thiamine substitution in alcohol dependent patients in withdrawal treatment].
Topics: Adult; Alcoholism; Cognition Disorders; Ethanol; Follow-Up Studies; Humans; Male; Middle Aged; Neuro | 1989 |
Effect of chronic ethanol administration on thiamine transport in microvillous vesicles of rat small intestine.
Topics: Alcoholism; Animals; Ethanol; Female; Intestinal Absorption; Intestine, Small; Male; Microvilli; Rat | 1989 |
[Lactic acidosis treated with thiamine. 3 cases].
Topics: Acidosis; Adult; Alcoholism; Beriberi; Erythrocytes; Humans; Lactates; Male; Middle Aged; Thiamine; | 1985 |
[Shoshin beriberi with hyponatremia in a beer drinker].
Topics: Adult; Alcoholism; Beer; Beriberi; Cardiovascular Diseases; Humans; Hyponatremia; Male; Thiamine | 1986 |
The haematic thiamine level in the course of alcoholic neuropathy.
Topics: Alcoholism; Erythrocytes; Humans; Peripheral Nervous System Diseases; Thiamine; Transketolase; Werni | 1987 |
Thiamin: to add or not to add?
Topics: Alcoholic Beverages; Alcoholism; Australia; Food, Fortified; Humans; Thiamine; Wernicke Encephalopat | 1988 |
[The clinical picture and treatment of stroke in alcoholics].
Topics: Adult; Alcoholism; Cerebrovascular Disorders; Drug Evaluation; Drug Therapy, Combination; Humans; Ma | 1988 |
Effect of acute and chronic ethanol administration on the transport of thiamine from plasma to different brain regions of the rat.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Blood-Brain Barrier; Brain; Cerebellum; Cerebral Cortex | 1988 |
Thiamin and alcoholic beverages: to add or not to add?
Topics: Adult; Alcoholic Beverages; Alcoholism; Female; Food Additives; Humans; Male; Middle Aged; Thiamine; | 1988 |
Fortification of beer and bread.
Topics: Alcoholism; Diet; Humans; Thiamine | 1988 |
Alcohol amblyopia.
Topics: Alcoholism; Amblyopia; Color Perception; Diet; Ethanol; Humans; Male; Middle Aged; Scotoma; Smoking; | 1988 |
Shoshin beriberi: a fulminant beriberi heart disease.
Topics: Acute Disease; Adult; Alcoholism; Beriberi; Heart Failure; Humans; Male; Thiamine; Vascular Resistan | 1988 |
The clinical spectrum of alcoholic pellagra encephalopathy. A retrospective analysis of 22 cases studied pathologically.
Topics: Adult; Aged; Alcoholism; Cognition Disorders; Confusion; Consciousness Disorders; Female; Humans; Ma | 1988 |
Changes in the activation of red blood cell transketolase of alcoholic patients during treatment.
Topics: Adult; Alcoholism; Enzyme Activation; Erythrocytes; Female; Humans; Male; Middle Aged; Thiamine; Tra | 1987 |
Thiamin status and biochemical indices of malnutrition and alcoholism in settled communities of !Kung San.
Topics: Adult; Alcoholism; Blood Chemical Analysis; Diet; Erythrocytes; Ethnicity; Female; Humans; Life Styl | 1987 |
Should thiamine be added to beer?
Topics: Alcohol Amnestic Disorder; Alcoholism; Beer; Humans; Thiamine; Wernicke Encephalopathy | 1986 |
Journal interview 11. Conversation with Jorge Mardones.
Topics: Alcohol Drinking; Alcoholism; Animals; Chile; Humans; Rats; Rats, Inbred Strains; Thiamine; Thiamine | 1986 |
Nutrition and alcoholic encephalopathies.
Topics: Alcoholism; Amino Acids; Animals; Brain; Humans; Liver; Models, Biological; Thiamine; Thiamine Defic | 1987 |
Thiamin in beer.
Topics: Alcoholism; Beer; Humans; Thiamine; Thiamine Deficiency | 1987 |
Beriberi heart disease in Durban. A retrospective study.
Topics: Acidosis; Adult; Alcoholism; Beriberi; Cardiomyopathies; Humans; Male; Middle Aged; Retrospective St | 1987 |
Acute Wernicke's encephalopathy in a recently recovered alcoholic.
Topics: Acute Disease; Adult; Alcoholism; Humans; Male; Thiamine; Wernicke Encephalopathy | 1986 |
The varied faces of Wernicke's encephalopathy.
Topics: Alcoholism; Humans; Nystagmus, Pathologic; Thiamine; Wernicke Encephalopathy | 1985 |
Wernicke's encephalopathy in a metropolitan hospital. A prospective study of incidence, characteristics and outcome.
Topics: Alcoholism; Australia; Erythrocytes; Female; Follow-Up Studies; Hospitals, Urban; Humans; Male; Midd | 1986 |
Jejunal uptake of thiamin hydrochloride in man: influence of alcoholism and alcohol.
Topics: Adult; Alcoholism; Ethanol; Humans; Intestinal Absorption; Jejunum; Male; Middle Aged; Nutritional P | 1985 |
[Subclinical alcoholic optic neuritis without vitamin deficiency].
Topics: Adult; Alcoholism; Ethanol; Female; Folic Acid; Humans; Lead; Male; Middle Aged; Optic Neuritis; Thi | 1985 |
Cerebral atrophy and hypoperfusion improve during treatment of Wernicke-Korsakoff syndrome.
Topics: Adult; Aged; Alcohol Amnestic Disorder; Alcoholism; Atrophy; Brain; Cerebrovascular Circulation; Hum | 1985 |
[Thiamine deficiency in chronic alcoholism. The effect of thiamine treatment on the erythrocyte transketolase activity and the thiamine pyrophosphate effect].
Topics: Adult; Aged; Alcoholism; Erythrocytes; Female; Humans; Male; Middle Aged; Thiamine; Thiamine Deficie | 1985 |
Massive thiamine dosage in an alcoholic with cerebellar cortical degeneration.
Topics: Administration, Oral; Alcoholism; Cerebellar Ataxia; Cerebellar Cortex; Cerebellar Diseases; Humans; | 1971 |
Letter: Hypothermia and Wernicke's encephalopathy.
Topics: Alcoholism; Humans; Hypothermia; Thiamine; Vitamin B Deficiency; Wernicke Encephalopathy | 1974 |
Influence of short-term alcohol consumption on the excretion of some components of the vitamin-B group in the urine of rats.
Topics: Alcoholism; Animals; Biological Assay; Biotin; Choline; Ethanol; Feces; Female; Fluorometry; Folic A | 1967 |
Motor conduction velocity in alcoholic patients.
Topics: Alcoholism; Demyelinating Diseases; Humans; Motor Neurons; Neural Conduction; Thiamine; Ulnar Nerve | 1968 |
Nutritional status of alcoholics.
Topics: Adult; Alcoholism; Bilirubin; Blood Proteins; Dietary Proteins; Female; Humans; Liver Function Tests | 1968 |
Choreoathetotic movement disorder in alcoholism.
Topics: Adult; Aged; Alcoholism; Athetosis; Chorea; Female; Humans; Huntington Disease; Liver Diseases; Magn | 1970 |
[Alcoholic cardiomyopathy].
Topics: Adult; Alcoholism; Anticoagulants; Autopsy; Beer; Cardiac Glycosides; Cardiomegaly; Cardiomyopathies | 1972 |
Beriberi heart disease.
Topics: Adult; Alcoholism; Beriberi; Cardiomegaly; Female; Humans; Thiamine | 1972 |
[Functional exploration of alcohol-tobacco induced optic neuritis].
Topics: Adult; Aged; Alcoholism; Color Perception Tests; Electroretinography; Humans; Middle Aged; Optic Neu | 1972 |
Blood thiamine and nicotinic acid levels in alcoholism and confusional states.
Topics: Adult; Aged; Alcoholism; Dementia; Humans; Intracranial Arteriosclerosis; Middle Aged; Neurologic Ma | 1967 |
[Dynamic exploration of alcohol ingestion in alcoholics with mental diseases].
Topics: Administration, Oral; Adult; Alcoholism; Capillaries; Ethanol; Humans; Liver Extracts; Male; Mental | 1972 |
Massive thiamine dosage in the treatment of acute alcoholic psychoses.
Topics: Alcoholism; Cardiomyopathies; Chlorpromazine; Death, Sudden; Female; Hospitalization; Humans; Inject | 1972 |
[Significance of ocular symptoms in the diagnosis of Wernicke's encephalopathy].
Topics: Abducens Nerve; Aged; Alcohol Amnestic Disorder; Alcoholism; Ataxia; Diagnosis, Differential; Eye Ma | 1972 |
Treatment for neurological complications of alcoholism.
Topics: Alcoholism; Diet Therapy; Humans; Neurologic Manifestations; Potassium; Thiamine | 1973 |
[Gayet-Wernicke alcoholic encephalopathy: the most important patterns of development, features of the clinical picture and therapy].
Topics: Acute Disease; Alcohol Amnestic Disorder; Alcoholism; Chronic Disease; Epilepsy; Humans; Movement Di | 1973 |
Prevention of alcohol withdrawal seizures: the roles of diphenylhydantoin and chlordiazepoxide.
Topics: Alcoholism; Anticonvulsants; Chlordiazepoxide; Electroencephalography; Ethanol; Humans; Neurons; Phe | 1973 |
Medical grand rounds from the University of Alabama Medical Center. Alcoholism.
Topics: Alcohol Amnestic Disorder; Alcohol Oxidoreductases; Alcoholism; Barbiturates; Drug Interactions; Eth | 1973 |
[Alcoholic myocardiography].
Topics: Adult; Alcoholism; Cardiomyopathies; Chronic Disease; Humans; Male; Middle Aged; Thiamine | 1974 |
Objective measurement of thiamine status by biochemical assay in adult Australians.
Topics: Adult; Alcoholism; Australia; Blood Donors; Erythrocytes; Female; Humans; Male; Middle Aged; Personn | 1974 |
[Treatment of alcohol intoxication].
Topics: Accidents, Home; Adult; Alcohol Amnestic Disorder; Alcoholic Intoxication; Alcoholism; Child; Chlord | 1974 |
Alcoholic myelopathy. With spastic urinary bladder.
Topics: Adult; Alcoholism; Diet Therapy; Electromyography; Humans; Male; Muscular Diseases; Thiamine; Urinar | 1972 |
Cardiac beriberi in Dublin.
Topics: Adult; Alcoholism; Beriberi; Cardiac Output; Electrocardiography; Heart Diseases; Humans; Male; Myoc | 1972 |
Acute pernicious beriberi heart disease.
Topics: Acidosis; Acute Disease; Adult; Alcoholism; Beriberi; Bicarbonates; Cardiac Output; Cardiomyopathies | 1972 |
Observations on the mechanism of thiamine hydrochloride absorption in man.
Topics: Adult; Aged; Alcoholism; Female; Humans; Ileum; Intestinal Absorption; Jejunum; Kinetics; Male; Midd | 1972 |
[2 cases of Gayet-Wernicke encephalopathy with unilateral isolated mydriasis].
Topics: Alcoholism; Eye Manifestations; Humans; Male; Middle Aged; Pupil; Thiamine; Thiamine Deficiency; Vis | 1971 |
Deficiency diseases of the nervous system secondary to alcoholism.
Topics: Alcohol Amnestic Disorder; Alcoholism; Amblyopia; Beriberi; Cerebellar Diseases; Deficiency Diseases | 1971 |
Vitamin deficits in severe alcoholic fatty liver of man calculated from multiple reference units.
Topics: Alcoholism; Autopsy; Biotin; DNA; Fatty Liver; Folic Acid; Humans; Nicotinic Acids; Pantothenic Acid | 1971 |
[Clinical picture and hemodynamics of the beri-beri myocardiopathy].
Topics: Adult; Alcoholism; Beriberi; Cardiomyopathies; Electrocardiography; Hemodynamics; Humans; Male; Thia | 1971 |
Beri-beri cardiomyopathy. Report of a case.
Topics: Alcoholism; Ascorbic Acid; Beer; Beriberi; Electrocardiography; Gastritis; Heart Diseases; Humans; M | 1965 |
[The Wernicke-Korsakoff syndrome and ataxia in alcoholics].
Topics: Alcohol Amnestic Disorder; Alcoholism; Cerebellar Ataxia; Humans; Thiamine; Wernicke Encephalopathy | 1969 |
[Value of combined arginine and vitamins B 1, B 6, B 12 b (26 cases)].
Topics: Alcoholism; Arginine; Drug Synergism; Humans; Male; Middle Aged; Pyridoxine; Thiamine; Vitamin B 12 | 1969 |
[Transketolase activity of erythrocytes of chronic alcoholic patients with assumed thiamine deficiency].
Topics: Adult; Aged; Alcoholism; Erythrocytes; Humans; Male; Middle Aged; Neurologic Manifestations; Thiamin | 1969 |
Persistence of low cardiac output after relief of high output by thiamine in a case of alcoholic beriberi and cardiac myopathy.
Topics: Adult; Alcoholism; Beriberi; Cardiac Output; Exercise Therapy; Heart Failure; Humans; Male; Myocardi | 1970 |
[2 cases of cardiac beriberi: notes on the physiopathology of cardiac manifestations in alcoholics].
Topics: Adult; Alcoholism; Beer; Beriberi; Cardiac Catheterization; Cardiac Output; Cardiomyopathies; Cobalt | 1970 |
[A case contribution on beriberi heart disease].
Topics: Adult; Alcoholism; Beriberi; Diagnosis, Differential; Gastrectomy; Heart Failure; Humans; Male; Thia | 1970 |
Recovery from proved Shoshin beriberi.
Topics: Acidosis; Adult; Alcoholism; Beriberi; Blood Gas Analysis; Blood Pressure; Cardiac Output; Cardiomyo | 1971 |
Thiamine propyl disulfide: absorption and utilization.
Topics: Administration, Oral; Adult; Alcoholism; Erythrocytes; Femoral Artery; Formates; Hepatic Veins; Huma | 1971 |
[Clinico-electroencephalographic correlations in Wernicke's encephalopathy with Korsakoff's syndrome].
Topics: Alcohol Amnestic Disorder; Alcoholism; Brain Diseases; Cerebral Hemorrhage; Electroencephalography; | 1967 |
Effect of magnesium deficiency on growth response to thiamine of thiamine-deficient rats.
Topics: Alcoholism; Animals; Diet; Female; Growth; Humans; Magnesium; Magnesium Deficiency; Rats; Thiamine; | 1968 |
Impairment of thiamine absorption in alcoholism.
Topics: Adult; Alcoholism; Feces; Female; Humans; Intestinal Absorption; Male; Middle Aged; Thiamine; Thiami | 1968 |
Vitamins of the B complex.
Topics: Aged; Alcoholism; Anemia, Hypochromic; Avitaminosis; Beriberi; Heart Failure; Humans; Isoniazid; Ner | 1968 |
Extraocular palsy and thiamine therapy in Wernicke's encephalopathy.
Topics: Adult; Alcoholism; Brain Diseases; Erythrocytes; Eye Manifestations; Humans; Ketones; Liver Cirrhosi | 1969 |
[Wernicke's encephalopathy].
Topics: Alcohol Amnestic Disorder; Alcoholism; Brain Stem; Female; Humans; Middle Aged; Thiamine; Thiamine D | 1969 |
Beriberi heart disease in London.
Topics: Adult; Alcoholism; Beriberi; Cardiac Output; Heart Diseases; Hemodynamics; Humans; Injections, Intra | 1969 |
Wernicke's encephalopathy. 3 Cases occurring in connection with severe malnutrition.
Topics: Adult; Alcoholism; Brain Stem; Electroencephalography; Female; Humans; Male; Middle Aged; Starvation | 1966 |
Thiamine, magnesium and plasma lactate abnormalities in alcoholic patients.
Topics: Alcoholism; Erythrocytes; Humans; In Vitro Techniques; Lactates; Magnesium; Magnesium Deficiency; Th | 1966 |
[The clinical aspects and the treatment of acute inflammatory or serous polyneuritis (syndrome of Landry, Guillain, Barré)].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Albumins; Alcoholism; Autonomic Nervo | 1966 |