thiamine has been researched along with Albuminuria in 13 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "High-dose supplements of thiamine prevent the development of microalbuminuria in experimental diabetes." | 9.14 | High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study. ( Akhtar, MW; Alam, SS; Larkin, JR; Rabbani, N; Riaz, S; Shafi, T; Thornalley, PJ, 2009) |
| "Thiamine deficiency has been linked to microvascular complications in patients with diabetes mellitus (DM)." | 5.38 | Blood thiamine and its phosphate esters as measured by high-performance liquid chromatography: levels and associations in diabetes mellitus patients with varying degrees of microalbuminuria. ( Abd-Alrahman, SH; Al-Attas, OS; Al-Daghri, NM; Alfadda, AA; Sabico, S, 2012) |
| "High-dose supplements of thiamine prevent the development of microalbuminuria in experimental diabetes." | 5.14 | High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study. ( Akhtar, MW; Alam, SS; Larkin, JR; Rabbani, N; Riaz, S; Shafi, T; Thornalley, PJ, 2009) |
| " Thiamine was found to be beneficial for reduction in albuminuria in a single study; however, there was lack of any improvement in kidney function or blood pressure following the use of vitamin B preparations used alone or in combination." | 4.91 | Vitamin B and its derivatives for diabetic kidney disease. ( Gor, D; Rangoonwala, AN; Raval, AD; Thakker, D; Walia, R, 2015) |
| "Thiamine (vitamin B1) is an essential cofactor in glucose metabolism, but it remains unclear whether thiamine status is lower in individuals with diabetes compared to individuals with normal glucose metabolism." | 3.01 | Association between diabetes and thiamine status - A systematic review and meta-analysis. ( Obeid, R; Reiners, K; Strom, A; Ziegler, D, 2023) |
| "Patients with type 2 diabetes and UAE equivalent to 15-300 mg/24 h, despite ACE inhibitors (ACE-Is) or angiotensin receptor blockers (ARBs), were randomly assigned to 12 weeks of benfotiamine (900 mg/day) (n = 39) or placebo (n = 43)." | 2.75 | A double-blind, randomized, placebo-controlled clinical trial on benfotiamine treatment in patients with diabetic nephropathy. ( Achenbach, U; Alkhalaf, A; Bakker, SJ; Bilo, HJ; Gans, RO; Kleefstra, N; Klooster, A; Mijnhout, GS; Navis, GJ; Slingerland, RJ; van Oeveren, W, 2010) |
| "Thiamine deficiency was highly prevalent in all groups, whereas low vitamin B₁₂ and elevated methylmalonic acid were rare." | 1.42 | Vitamin B status in patients with type 2 diabetes mellitus with and without incipient nephropathy. ( Bangert, V; Hostalek, U; Kaiser, RP; Nix, WA; Obeid, R; Schilling, M; Zirwes, R, 2015) |
| "Thiamine deficiency has been linked to microvascular complications in patients with diabetes mellitus (DM)." | 1.38 | Blood thiamine and its phosphate esters as measured by high-performance liquid chromatography: levels and associations in diabetes mellitus patients with varying degrees of microalbuminuria. ( Abd-Alrahman, SH; Al-Attas, OS; Al-Daghri, NM; Alfadda, AA; Sabico, S, 2012) |
| "One hundred and fifteen patients with type 2 diabetes with and without microalbuminuria or albuminuria and 39 healthy people were recruited." | 1.38 | Disturbance of B-vitamin status in people with type 2 diabetes in Indonesia--link to renal status, glycemic control and vascular inflammation. ( Adaikalakoteswari, A; Adam, JM; Kariadi, SH; Rabbani, N; Thornalley, PJ; Tjokroprawiro, A; Waspadji, S, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 8 (61.54) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Ziegler, D | 1 |
| Reiners, K | 1 |
| Strom, A | 1 |
| Obeid, R | 2 |
| Nix, WA | 1 |
| Zirwes, R | 1 |
| Bangert, V | 1 |
| Kaiser, RP | 1 |
| Schilling, M | 1 |
| Hostalek, U | 1 |
| Raval, AD | 1 |
| Thakker, D | 1 |
| Rangoonwala, AN | 1 |
| Gor, D | 1 |
| Walia, R | 1 |
| Rabbani, N | 4 |
| Alam, SS | 1 |
| Riaz, S | 2 |
| Larkin, JR | 1 |
| Akhtar, MW | 1 |
| Shafi, T | 1 |
| Thornalley, PJ | 6 |
| Alkhalaf, A | 2 |
| Kleefstra, N | 2 |
| Groenier, KH | 1 |
| Bakker, SJ | 2 |
| Navis, GJ | 2 |
| Bilo, HJ | 2 |
| Klooster, A | 1 |
| van Oeveren, W | 1 |
| Achenbach, U | 1 |
| Slingerland, RJ | 1 |
| Mijnhout, GS | 1 |
| Gans, RO | 1 |
| Skinner, V | 1 |
| Srai, SK | 1 |
| Kihm, LP | 1 |
| Müller-Krebs, S | 1 |
| Klein, J | 1 |
| Ehrlich, G | 1 |
| Mertes, L | 1 |
| Gross, ML | 1 |
| Adaikalakoteswari, A | 2 |
| Hammes, HP | 1 |
| Nawroth, PP | 1 |
| Zeier, M | 1 |
| Schwenger, V | 1 |
| Al-Attas, OS | 1 |
| Al-Daghri, NM | 1 |
| Alfadda, AA | 1 |
| Abd-Alrahman, SH | 1 |
| Sabico, S | 1 |
| Waspadji, S | 1 |
| Tjokroprawiro, A | 1 |
| Kariadi, SH | 1 |
| Adam, JM | 1 |
| Babaei-Jadidi, R | 2 |
| Karachalias, N | 1 |
| Ahmed, N | 1 |
| Battah, S | 1 |
| Al Ali, H | 1 |
| Antonysunil, A | 1 |
| Larkin, J | 1 |
| Ahmed, A | 1 |
| Rayman, G | 1 |
| Bodmer, CW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Vitamin B Status in Type 2 Diabetes (VITA) Study[NCT03447275] | 174 participants (Actual) | Observational | 2011-01-31 | Completed | |||
| A Double-Blind Clinical Trial of Benfotiamine Treatment in Diabetic Nephropathy[NCT00565318] | Phase 4 | 86 participants (Anticipated) | Interventional | 2007-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for thiamine and Albuminuria
| Article | Year |
|---|---|
Association between diabetes and thiamine status - A systematic review and meta-analysis.
Topics: Albuminuria; Diabetes Mellitus; Glucose; Humans; Thiamine; Thiamine Pyrophosphate | 2023 |
Vitamin B and its derivatives for diabetic kidney disease.
Topics: Albuminuria; Diabetic Nephropathies; Folic Acid; Humans; Pyridoxamine; Randomized Controlled Trials | 2015 |
Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy.
Topics: Albuminuria; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropat | 2011 |
3 trials available for thiamine and Albuminuria
| Article | Year |
|---|---|
High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study.
Topics: Albuminuria; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Glomerular Filtration R | 2009 |
A double-blind, randomized, placebo-controlled clinical trial on benfotiamine treatment in patients with diabetic nephropathy.
Topics: Adjuvants, Immunologic; Adult; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotens | 2010 |
Effect of high dose thiamine on the levels of urinary protein biomarkers in diabetes mellitus type 2.
Topics: Adult; Aged; Albuminuria; Biomarkers; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type | 2011 |
7 other studies available for thiamine and Albuminuria
| Article | Year |
|---|---|
Vitamin B status in patients with type 2 diabetes mellitus with and without incipient nephropathy.
Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Biomarkers; Case-Control Studies; Diabetes Mellitus, Ty | 2015 |
Thiamine in diabetic nephropathy: a novel treatment modality?
Topics: Albuminuria; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; | 2009 |
Benfotiamine protects against peritoneal and kidney damage in peritoneal dialysis.
Topics: Albuminuria; Animals; Fibrosis; Glycation End Products, Advanced; Kidney; Male; Peritoneal Dialysis; | 2011 |
Blood thiamine and its phosphate esters as measured by high-performance liquid chromatography: levels and associations in diabetes mellitus patients with varying degrees of microalbuminuria.
Topics: Adolescent; Adult; Aged; Albuminuria; Blood Glucose; Child; Child, Preschool; Cholesterol; Chromatog | 2012 |
Disturbance of B-vitamin status in people with type 2 diabetes in Indonesia--link to renal status, glycemic control and vascular inflammation.
Topics: Albuminuria; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Indonesia; In | 2012 |
Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine.
Topics: Albuminuria; Animals; Chelating Agents; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dos | 2003 |
High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease.
Topics: Albuminuria; Biomarkers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies | 2007 |