thiamine has been researched along with Akinetic-Rigid Variant of Huntington Disease in 4 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thiamine/biotin treatment of R6/1 HD mice to compensate for TPK1 dysregulation restores OL maturation and rescues neuronal pathology." | 5.72 | Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. ( Adam, M; Al-Dalahmah, O; Casaccia, P; Dansu, DK; Davidson, S; Flowers, XE; Fraenkel, E; Gold, MP; Goldman, JE; Hickman, RA; Khan, F; Lau, A; Lim, RG; McClure, N; Menon, V; Michael, N; Miramontes, R; Miyoshi, E; Ofori, K; Park, HJ; Paryani, F; Reidling, JC; Reyes-Ortiz, AM; Swarup, V; Tang, A; Tang, G; Thompson, LM; Vonsattel, JP; Wu, J, 2022) |
| " It was not associated with gross liver disease, phenothiazine administration, or familial chorea, and no consistent abnormalities in whole blood thiamine or nicotinic acid, in serum magnesium, or in serum vitamin B(12) levels were present." | 3.65 | Choreoathetotic movement disorder in alcoholism. ( Bolt, JM; Kershaw, PW; Mullin, PJ, 1970) |
| "Thiamine/biotin treatment of R6/1 HD mice to compensate for TPK1 dysregulation restores OL maturation and rescues neuronal pathology." | 1.72 | Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. ( Adam, M; Al-Dalahmah, O; Casaccia, P; Dansu, DK; Davidson, S; Flowers, XE; Fraenkel, E; Gold, MP; Goldman, JE; Hickman, RA; Khan, F; Lau, A; Lim, RG; McClure, N; Menon, V; Michael, N; Miramontes, R; Miyoshi, E; Ofori, K; Park, HJ; Paryani, F; Reidling, JC; Reyes-Ortiz, AM; Swarup, V; Tang, A; Tang, G; Thompson, LM; Vonsattel, JP; Wu, J, 2022) |
| "1 patient with Wernicke syndrome showed a remarkable improvement of saccadic velocity following thiamine administration." | 1.26 | [Slowed saccades in various neurological disorders]. ( Hamann, KU, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lim, RG | 1 |
| Al-Dalahmah, O | 1 |
| Wu, J | 1 |
| Gold, MP | 1 |
| Reidling, JC | 1 |
| Tang, G | 1 |
| Adam, M | 1 |
| Dansu, DK | 1 |
| Park, HJ | 1 |
| Casaccia, P | 1 |
| Miramontes, R | 1 |
| Reyes-Ortiz, AM | 1 |
| Lau, A | 1 |
| Hickman, RA | 1 |
| Khan, F | 1 |
| Paryani, F | 1 |
| Tang, A | 1 |
| Ofori, K | 1 |
| Miyoshi, E | 1 |
| Michael, N | 1 |
| McClure, N | 1 |
| Flowers, XE | 1 |
| Vonsattel, JP | 1 |
| Davidson, S | 1 |
| Menon, V | 1 |
| Swarup, V | 1 |
| Fraenkel, E | 1 |
| Goldman, JE | 1 |
| Thompson, LM | 1 |
| Gruber-Bzura, BM | 1 |
| Krzysztoń-Russjan, J | 1 |
| Bubko, I | 1 |
| Syska, J | 1 |
| Jaworska, M | 1 |
| Zmysłowski, A | 1 |
| Rosłon, M | 1 |
| Drozd, J | 1 |
| Drozd, E | 1 |
| Majorczyk, E | 1 |
| Anuszewska, EL | 1 |
| Hamann, KU | 1 |
| Mullin, PJ | 1 |
| Kershaw, PW | 1 |
| Bolt, JM | 1 |
4 other studies available for thiamine and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Topics: Animals; Biotin; Dietary Supplements; Disease Models, Animal; Humans; Huntington Disease; Mice; Mice | 2022 |
Role of thiamine in Huntington's disease pathogenesis: In vitro studies.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adenosine Triphosphate; B-Lymphocytes; Case-Contr | 2017 |
[Slowed saccades in various neurological disorders].
Topics: Aged; Brain Diseases; Child; Electrooculography; Eye Movements; Humans; Huntington Disease; Male; Mi | 1979 |
Choreoathetotic movement disorder in alcoholism.
Topics: Adult; Aged; Alcoholism; Athetosis; Chorea; Female; Humans; Huntington Disease; Liver Diseases; Magn | 1970 |