thiamine has been researched along with Acute Kidney Failure in 16 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
Excerpt | Relevance | Reference |
---|---|---|
"Our results suggest that the early use of intravenous vitamin C, together with corticosteroids and thiamine, are effective in preventing progressive organ dysfunction, including acute kidney injury, and in reducing the mortality of patients with severe sepsis and septic shock." | 7.85 | Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study. ( Catravas, J; Hooper, MH; Khangoora, V; Marik, PE; Rivera, R, 2017) |
" Since thiamine pyrophosphate is a cofactor in the reaction, thiamine deficiency might be expected to result in tissue oxalosis." | 7.65 | Thiamine deficiency and oxalosis. ( Salyer, DC; Salyer, WR, 1974) |
"Methods: Sepsis was induced using the cecal ligation and puncture (CLP) model of sepsis with fluid and antibiotic support." | 5.72 | HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS. ( Kim, J; Remick, D; Stolarski, A; Wee, K; Zhang, Q, 2022) |
"Our results suggest that the early use of intravenous vitamin C, together with corticosteroids and thiamine, are effective in preventing progressive organ dysfunction, including acute kidney injury, and in reducing the mortality of patients with severe sepsis and septic shock." | 3.85 | Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study. ( Catravas, J; Hooper, MH; Khangoora, V; Marik, PE; Rivera, R, 2017) |
"Ethylene glycol toxicity has produced central nervous system abnormalities including coma, cerebral edema, and cranial nerve dysfunction." | 3.70 | Ethylene glycol ingestion resulting in brainstem and midbrain dysfunction. ( Follmer, R; Ford, MD; Morgan, BW, 2000) |
" Since thiamine pyrophosphate is a cofactor in the reaction, thiamine deficiency might be expected to result in tissue oxalosis." | 3.65 | Thiamine deficiency and oxalosis. ( Salyer, DC; Salyer, WR, 1974) |
"Acute renal failure is a serious complication in critically ill patients and frequently requires renal replacement therapy, which alters trace element and vitamin metabolism." | 2.71 | Copper, selenium, zinc, and thiamine balances during continuous venovenous hemodiafiltration in critically ill patients. ( Baines, M; Berger, MM; Cayeux, MC; Chioléro, RL; Revelly, JP; Roberts, E; Shenkin, A, 2004) |
"Methods: Sepsis was induced using the cecal ligation and puncture (CLP) model of sepsis with fluid and antibiotic support." | 1.72 | HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS. ( Kim, J; Remick, D; Stolarski, A; Wee, K; Zhang, Q, 2022) |
"Tacrolimus is an immunosuppressant widely used in recipients of solid organ transplants to prevent rejection." | 1.35 | Acute tacrolimus toxicity in a non-transplant patient. ( Mowry, J; O'Connor, AD; Rusyniak, DE, 2008) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (31.25) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (18.75) | 29.6817 |
2010's | 3 (18.75) | 24.3611 |
2020's | 5 (31.25) | 2.80 |
Authors | Studies |
---|---|
Kim, J | 3 |
Stolarski, A | 3 |
Zhang, Q | 3 |
Wee, K | 3 |
Remick, D | 3 |
Al-Kharashi, L | 1 |
Attia, H | 1 |
Alsaffi, A | 1 |
Almasri, T | 1 |
Arafa, M | 1 |
Hasan, I | 1 |
Alajami, H | 1 |
Ali, R | 1 |
Badr, A | 1 |
Dhanani, LY | 1 |
Totton, RR | 1 |
Jara-Quijada, E | 1 |
Pérez-Won, M | 1 |
Tabilo-Munizaga, G | 1 |
Lemus-Mondaca, R | 1 |
González-Cavieres, L | 1 |
Palma-Acevedo, A | 1 |
Herrera-Lavados, C | 1 |
Milovanovic, S | 1 |
Grzegorczyk, A | 1 |
Świątek, Ł | 1 |
Grzęda, A | 1 |
Dębczak, A | 1 |
Tyskiewicz, K | 1 |
Konkol, M | 1 |
Li, Y | 2 |
Chang, P | 1 |
Sankaran, S | 1 |
Jang, H | 1 |
Nie, Y | 1 |
Zeng, A | 1 |
Hussain, S | 1 |
Wu, JY | 1 |
Chen, X | 2 |
Shi, L | 2 |
Senapati, A | 1 |
Chetri, BK | 1 |
Mitra, S | 1 |
Shelke, RG | 1 |
Rangan, L | 1 |
Chauhan, AS | 1 |
Tiwari, M | 1 |
Indoliya, Y | 1 |
Mishra, SK | 1 |
Lavania, UC | 1 |
Chauhan, PS | 1 |
Chakrabarty, D | 1 |
Tripathi, RD | 1 |
Akaputra, R | 1 |
Hatta, M | 1 |
Massi, MN | 1 |
Djaharuddin, I | 1 |
Bukhari, A | 1 |
Aminuddin, A | 1 |
Santoso, A | 1 |
Natzir, R | 1 |
Bahar, B | 1 |
Fachri, M | 1 |
Farsida, F | 1 |
Fathimah, A | 1 |
Ubaidah, FM | 1 |
Sridiana, E | 1 |
Dwiyanti, R | 1 |
Syukri, A | 1 |
Junita, AR | 1 |
Febrianti, A | 1 |
Primaguna, MR | 1 |
Azhar, A | 1 |
Rajaure, YS | 1 |
Thapa, B | 1 |
Budhathoki, L | 1 |
Rana, SR | 1 |
Khadka, M | 1 |
Batchu, UR | 1 |
Surapaneni, JR | 1 |
Cheemalamarri, C | 1 |
Mandava, K | 1 |
Puvvada, N | 1 |
Shetty, PR | 1 |
Mv, S | 1 |
Ranjbarian, P | 1 |
Goudarzi, F | 1 |
Akya, A | 1 |
Heidarinia, H | 1 |
Farasat, A | 1 |
Rostamian, M | 1 |
Suri, K | 1 |
Rajput, N | 1 |
Sharma, P | 1 |
Omble, AD | 1 |
Kulkarni, K | 1 |
Gahlay, GK | 1 |
Fernandez Garcia, E | 1 |
Paudel, U | 1 |
Noji, MC | 1 |
Bowman, CE | 1 |
Rustgi, AK | 1 |
Pitarresi, JR | 1 |
Wellen, KE | 1 |
Arany, Z | 1 |
Weissenrieder, JS | 1 |
Foskett, JK | 1 |
Lee, MS | 1 |
Han, HJ | 1 |
Choi, TI | 1 |
Lee, KH | 1 |
Baasankhuu, A | 1 |
Kim, HT | 1 |
Kim, CH | 1 |
Redd, PS | 1 |
Payero, L | 1 |
Gilbert, DM | 1 |
Page, CA | 1 |
King, R | 1 |
McAssey, EV | 1 |
Bodie, D | 1 |
Diaz, S | 1 |
Hancock, CN | 1 |
Lee, HS | 1 |
Jung, S | 1 |
Lee, SW | 1 |
Kim, YT | 1 |
Lee, J | 1 |
Ren, T | 1 |
Yu, Z | 1 |
Yu, H | 1 |
Deng, K | 1 |
Wang, Z | 1 |
Li, X | 1 |
Wang, H | 1 |
Wang, L | 2 |
Xu, Y | 1 |
Lascano, J | 1 |
Riley, L | 1 |
Khodayari, N | 1 |
Brantly, M | 1 |
Gupta, R | 1 |
Pradhan, J | 1 |
Haldar, A | 1 |
Murapaka, C | 1 |
Chandra Mondal, P | 1 |
Gao, R | 1 |
Dai, TY | 1 |
Meng, Z | 1 |
Sun, XF | 1 |
Liu, DX | 1 |
Shi, MM | 1 |
Li, HR | 1 |
Kang, X | 1 |
Bi, B | 1 |
Zhang, YT | 1 |
Xu, TW | 1 |
Yan, JM | 1 |
Jiang, Q | 1 |
Helmchen, G | 1 |
Guo, H | 1 |
Xiang, W | 1 |
Fang, Y | 1 |
Li, J | 4 |
Lin, Y | 1 |
An, X | 1 |
Jiang, D | 1 |
Cao, Q | 1 |
Xu, F | 1 |
Shiigi, H | 1 |
Wang, W | 1 |
Chen, Z | 1 |
Akosman, I | 1 |
Kumar, N | 1 |
Mortenson, R | 1 |
Lans, A | 1 |
De La Garza Ramos, R | 1 |
Eleswarapu, A | 1 |
Yassari, R | 1 |
Fourman, MS | 1 |
Jana, S | 1 |
Evans, EGB | 1 |
Jang, HS | 1 |
Zhang, S | 2 |
Zhang, H | 1 |
Rajca, A | 1 |
Gordon, SE | 1 |
Zagotta, WN | 1 |
Stoll, S | 1 |
Mehl, RA | 1 |
Miller, S | 1 |
Lee, DA | 1 |
Muhimpundu, S | 1 |
Maxwell, CA | 1 |
Liu, Z | 1 |
Shen, F | 1 |
Tong, Q | 1 |
Tang, M | 1 |
Peng, M | 1 |
Jiao, Z | 1 |
Jiang, Y | 1 |
Ao, L | 1 |
Fu, W | 1 |
Lv, X | 1 |
Jiang, G | 1 |
Hou, L | 1 |
Tu, WC | 1 |
McManamen, AM | 1 |
Su, X | 1 |
Jeacopello, I | 1 |
Takezawa, MG | 1 |
Hieber, DL | 1 |
Hassan, GW | 1 |
Lee, UN | 1 |
Anana, EV | 1 |
Locknane, MP | 1 |
Stephenson, MW | 1 |
Shinkawa, VAM | 1 |
Wald, ER | 1 |
DeMuri, GP | 1 |
Adams, KN | 1 |
Berthier, E | 1 |
Thongpang, S | 1 |
Theberge, AB | 1 |
Jiang, L | 1 |
Li, Z | 1 |
Dong, Q | 1 |
Rong, X | 1 |
Dong, G | 1 |
Huang, J | 1 |
Liang, Y | 1 |
Sun, S | 1 |
Zhang, R | 1 |
Miao, Z | 1 |
Senju, C | 1 |
Nakazawa, Y | 1 |
Oso, T | 1 |
Shimada, M | 1 |
Kato, K | 1 |
Matsuse, M | 1 |
Tsujimoto, M | 1 |
Masaki, T | 1 |
Miyazaki, Y | 1 |
Fukushima, S | 1 |
Tateishi, S | 1 |
Utani, A | 1 |
Murota, H | 1 |
Tanaka, K | 1 |
Mitsutake, N | 1 |
Moriwaki, S | 1 |
Nishigori, C | 1 |
Ogi, T | 1 |
Liu, C | 1 |
Zhang, X | 1 |
Wang, B | 1 |
Luo, Z | 1 |
Qian, D | 1 |
Liu, J | 1 |
Waterhouse, GIN | 1 |
Barbosa, M | 1 |
Marques-Sá, J | 1 |
Carvalho, C | 1 |
Fernandes, V | 1 |
Grilli, D | 1 |
Smetana, V | 1 |
Ahmed, SJ | 1 |
Shtender, V | 1 |
Pani, M | 1 |
Manfrinetti, P | 1 |
Mudring, AV | 1 |
Kuang, Y | 1 |
Yang, D | 1 |
Gai, S | 1 |
He, F | 1 |
An, B | 1 |
Yang, P | 1 |
Notini, L | 1 |
Schulz, K | 1 |
Kubeneck, LJ | 1 |
Grigg, ARC | 1 |
Rothwell, KA | 1 |
Fantappiè, G | 1 |
ThomasArrigo, LK | 1 |
Kretzschmar, R | 1 |
Siswanto, FM | 1 |
Okukawa, K | 1 |
Tamura, A | 1 |
Oguro, A | 1 |
Imaoka, S | 1 |
Kim, CG | 1 |
Jung, M | 1 |
Kim, HS | 1 |
Lee, CK | 1 |
Jeung, HC | 1 |
Koo, DH | 1 |
Bae, WK | 1 |
Zang, DY | 1 |
Kim, BJ | 1 |
Kim, H | 1 |
Yun, UJ | 1 |
Che, J | 1 |
Park, S | 1 |
Kim, TS | 1 |
Kwon, WS | 1 |
Park, J | 1 |
Cho, SW | 1 |
Nam, CM | 1 |
Chung, HC | 1 |
Rha, SY | 1 |
Colombo, N | 1 |
Van Gorp, T | 1 |
Matulonis, UA | 1 |
Oaknin, A | 1 |
Grisham, RN | 1 |
Fleming, GF | 1 |
Olawaiye, AB | 1 |
Nguyen, DD | 1 |
Greenstein, AE | 1 |
Custodio, JM | 1 |
Pashova, HI | 1 |
Tudor, IC | 1 |
Lorusso, D | 1 |
Zhou, F | 1 |
Jiang, Z | 1 |
Liang, H | 1 |
Ru, S | 1 |
Bettiol, AA | 1 |
Gao, W | 1 |
Lipsyc-Sharf, M | 1 |
Jain, E | 1 |
Collins, LC | 1 |
Rosenberg, SM | 1 |
Ruddy, KJ | 1 |
Tamimi, RM | 1 |
Schapira, L | 1 |
Come, SE | 1 |
Peppercorn, JM | 1 |
Borges, VF | 1 |
Warner, E | 1 |
Snow, C | 1 |
Krop, IE | 1 |
Kim, D | 1 |
Weiss, J | 1 |
Zanudo, JGT | 1 |
Partridge, AH | 1 |
Wagle, N | 1 |
Waks, AG | 1 |
Moskowitz, A | 2 |
Berg, KM | 1 |
Grossestreuer, AV | 1 |
Balaji, L | 1 |
Liu, X | 1 |
Cocchi, MN | 2 |
Chase, M | 1 |
Gong, MN | 1 |
Gong, J | 1 |
Parikh, SM | 1 |
Ngo, L | 1 |
Berlin, N | 1 |
Donnino, MW | 2 |
Zhou, Y | 1 |
Chen, Q | 1 |
Zhong, S | 1 |
Liu, H | 1 |
Koh, K | 1 |
Chen, H | 1 |
He, J | 1 |
Chen, J | 1 |
Liu, S | 1 |
Lin, L | 1 |
Zhang, Y | 1 |
Xiao, S | 1 |
Cao, S | 1 |
Yan, B | 2 |
Deng, J | 1 |
Gu, J | 1 |
Tao, Y | 1 |
Huang, C | 1 |
Lai, C | 1 |
Yong, Q | 1 |
Shen, Y | 1 |
Gong, Z | 1 |
Cao, J | 1 |
Mao, W | 1 |
Yao, Y | 1 |
Zhao, J | 1 |
Li, Q | 1 |
Liu, K | 1 |
Liu, B | 1 |
Feng, S | 1 |
Chandran, V | 1 |
Kunjan, C | 1 |
Veerapandian, V | 1 |
Kannan, R | 1 |
Zhang, T | 1 |
von Gunten, U | 1 |
Caruso, FR | 1 |
Goulart, CDL | 1 |
Jr, JCB | 1 |
de Oliveira, CR | 1 |
Mendes, RG | 1 |
Arena, R | 1 |
Borghi-Silva, A | 1 |
Carrasco-Nuñes, N | 1 |
Romano, M | 1 |
Cabeza, M | 1 |
Jiang, B | 1 |
Chen, D | 1 |
Zhao, C | 1 |
Ma, Y | 1 |
Yang, W | 1 |
Shen, X | 1 |
Satheeshkumar, K | 1 |
Saravanakumar, P | 1 |
Kalavathi, A | 1 |
Vennila, KN | 1 |
Elango, KP | 1 |
Mues Genannt Koers, L | 1 |
Prevost, D | 1 |
Paulssen, E | 1 |
Hoehr, C | 1 |
Ulhassan, Z | 1 |
Yang, S | 1 |
He, D | 1 |
Khan, AR | 1 |
Salam, A | 1 |
Azhar, W | 1 |
Muhammad, S | 1 |
Ali, S | 1 |
Hamid, Y | 1 |
Khan, I | 1 |
Sheteiwy, MS | 1 |
Zhou, W | 1 |
Wang, X | 1 |
Xie, Q | 1 |
Wang, Y | 1 |
Lü, H | 1 |
Fu, M | 1 |
Wang, D | 1 |
Jazayeri, A | 1 |
Nonga, D | 1 |
Rao, M | 1 |
Legouis, D | 1 |
Ricksten, SE | 1 |
Faivre, A | 1 |
Verissimo, T | 1 |
Gariani, K | 1 |
Verney, C | 1 |
Galichon, P | 1 |
Berchtold, L | 1 |
Feraille, E | 1 |
Fernandez, M | 1 |
Placier, S | 1 |
Koppitch, K | 1 |
Hertig, A | 1 |
Martin, PY | 1 |
Naesens, M | 1 |
Pugin, J | 1 |
McMahon, AP | 1 |
Cippà, PE | 1 |
de Seigneux, S | 1 |
Freire-Aragón, MD | 1 |
Fernández Delgado, E | 1 |
Carbajal-Guerrero, J | 1 |
Ribera-Rubiales, G | 1 |
Marik, PE | 1 |
Khangoora, V | 1 |
Rivera, R | 1 |
Hooper, MH | 1 |
Catravas, J | 1 |
Andersen, LW | 1 |
Karlsson, M | 1 |
Patel, PV | 1 |
O'Connor, AD | 1 |
Rusyniak, DE | 1 |
Mowry, J | 1 |
BERNING, H | 1 |
Berger, MM | 1 |
Shenkin, A | 1 |
Revelly, JP | 1 |
Roberts, E | 1 |
Cayeux, MC | 1 |
Baines, M | 1 |
Chioléro, RL | 1 |
Webb, DI | 1 |
Oda, R | 1 |
Okumura, M | 1 |
Yamano, S | 1 |
Yoshimura, H | 1 |
Severova, EIa | 1 |
Karmysheva, VIa | 1 |
Balkarova, OV | 1 |
Morgan, BW | 1 |
Ford, MD | 1 |
Follmer, R | 1 |
Salyer, WR | 1 |
Salyer, DC | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effect of Combined Vitamin C, Stress-dose Steroids, and Thiamine on Cerebral Autoregulation and Functional Outcomes of Patients With Septic Shock[NCT03649633] | Phase 1/Phase 2 | 100 participants (Anticipated) | Interventional | 2018-09-06 | Recruiting | ||
Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock[NCT03828929] | Phase 3 | 3 participants (Actual) | Interventional | 2019-10-15 | Terminated (stopped due to Recent similar studies have been completed and published showing no benefit to the intervention.) | ||
Impact of Thiamine Supplementation on Mortality in Septic Shock. A Controlled Before-and-after Study.[NCT05840718] | 80 participants (Anticipated) | Observational | 2023-09-30 | Not yet recruiting | |||
Effect of Intravenous Vitamin C on Sequential Organ Failure Assessment (SOFA) Score Among Septic Patients: Randomized Controlled Trial[NCT04137276] | 33 participants (Actual) | Interventional | 2019-04-01 | Completed | |||
Early High-dose Vitamin C in Post-cardiac Arrest Syndrome[NCT03509662] | Phase 2 | 270 participants (Anticipated) | Interventional | 2019-10-07 | Recruiting | ||
Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock[NCT03380507] | Phase 2/Phase 3 | 106 participants (Actual) | Interventional | 2018-03-17 | Terminated (stopped due to The research is no longer funded and terminated due to futility) | ||
Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis.[NCT03422159] | Phase 2 | 140 participants (Actual) | Interventional | 2018-02-05 | Completed | ||
Ascorbic Ccid, Hydrocortisone, and Thiamine in Sepsis and Septic Shock - A Randomized, Double-Blind, Placebo-Controlled Trial[NCT03389555] | Phase 2/Phase 3 | 205 participants (Actual) | Interventional | 2018-02-09 | Completed | ||
Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock: a Randomized Clinical Study (VITAMIN TRIAL)[NCT05192213] | Phase 3 | 1,090 participants (Anticipated) | Interventional | 2021-08-01 | Recruiting | ||
Combination Therapy of Vitamin C and Thiamine for Septic Shock: Multi-center, Double-blinded, Randomized, Controlled Study[NCT03756220] | Phase 2 | 116 participants (Actual) | Interventional | 2018-12-01 | Completed | ||
A Randomized, Double Blind, Placebo-Controlled Trial to Investigate the Effect of Vitamin C, Hydrocortisone and Thiamine on the Outcome of Patients With Septic Shock[NCT03592693] | Phase 2 | 400 participants (Anticipated) | Interventional | 2018-09-06 | Recruiting | ||
Effects of Vitamin C Administration on Extravascular Lung Water in Patients With Severe Features of Preeclampsia: a Randomized, Placebo-controlled Trial[NCT03451266] | Phase 1 | 34 participants (Actual) | Interventional | 2018-04-07 | Completed | ||
A Randomized, Double Blind, Placebo-Controlled Study to Investigate the Effects of Vitamin C, Hydrocortisone and Thiamine on the Outcome of Patients With Severe Sepsis and Septic Shock[NCT03335124] | Phase 4 | 5 participants (Actual) | Interventional | 2017-09-26 | Terminated (stopped due to Due to insufficient recruitment) | ||
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock: A Prospective Study[NCT03258684] | 80 participants (Actual) | Interventional | 2017-09-25 | Completed | |||
Thiamine as a Renal Protective Agent in Septic Shock: A Randomized, Controlled Study[NCT03550794] | Phase 2 | 95 participants (Actual) | Interventional | 2018-09-04 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Defined as the day 4 post-randomization SOFA score minus the initial SOFA score. The Sequential Organ Failure Assessment (SOFA) Score is a mortality prediction score that is based on the degree of dysfunction of six organ systems. The score is calculated on admission and every 24 hours until discharge using the worst parameters measured during the prior 24 hours SOFA score ranges from 0 (no organ dysfunction) to 24 (highest possible score / organ dysfunction). (NCT03422159)
Timeframe: 4 days post-randomization
Intervention | score on a scale (Mean) |
---|---|
Treatment Arm | 2.9 |
Placebo Arm | 1.93 |
Time from admitting to discharge of hospital stay. (NCT03422159)
Timeframe: From admission to the hospital until final discharge, up to 28 days.
Intervention | Days (Mean) |
---|---|
Treatment Arm | 11.5 |
Placebo Arm | 11 |
In-hospital mortality rate. (NCT03422159)
Timeframe: Survival until hospital discharge, up to 28 days.
Intervention | Participants (Count of Participants) |
---|---|
Treatment Arm | 11 |
Placebo Arm | 13 |
Time from admitting to ICU to discharge. (NCT03422159)
Timeframe: From admission to the ICU until final discharge from the ICU, up to an average of 7 days.
Intervention | days (Mean) |
---|---|
Treatment Arm | 4.76 |
Placebo Arm | 4.66 |
ICU mortality rate (NCT03422159)
Timeframe: From admission to hospital until final discharge from the ICU, up to 28 days.
Intervention | Participants (Count of Participants) |
---|---|
Treatment Arm | 6 |
Placebo Arm | 10 |
PCT at 96 hours minus initial PCT, divided by the initial PCT multiplied by 100. (NCT03422159)
Timeframe: 4 days post-randomization
Intervention | Percent (Mean) |
---|---|
Treatment Arm | 63 |
Placebo Arm | 58 |
Defined as the time from starting the active treatment/placebo to discontinuation of all pressors. (NCT03422159)
Timeframe: From start of vasopressor medication to final discontinuation of vasopressor medication, up to 7 days.
Intervention | hours (Mean) |
---|---|
HAT Treatment | 27 |
Comparator | 53 |
Number of days alive and off of the ventilator at day 28. (NCT03422159)
Timeframe: 28 Days post-randomization
Intervention | Days (Mean) |
---|---|
Treatment Arm | 22 |
Placebo Arm | 22.4 |
Mortality rate (NCT03389555)
Timeframe: Enrollment until 30-days after enrollment
Intervention | Participants (Count of Participants) |
---|---|
Vitamin C, Vitamin B1, Corticosteroids | 35 |
Placebo | 29 |
Home hospital disposition in patients who survive to discharge (NCT03389555)
Timeframe: Enrollment until hospital discharge, death, or 30-days, whichever comes first.
Intervention | Participants (Count of Participants) |
---|---|
Vitamin C, Vitamin B1, Corticosteroids | 34 |
Placebo | 35 |
Hospital mortality rate (NCT03389555)
Timeframe: Enrollment until hospital discharge, death, or 30-days. Whichever comes first.
Intervention | Participants (Count of Participants) |
---|---|
Vitamin C, Vitamin B1, Corticosteroids | 28 |
Placebo | 23 |
Number of days that the patient was not in the ICU. Timeframe listed below. (NCT03389555)
Timeframe: From enrollment until 28 days after enrollment
Intervention | Days (Median) |
---|---|
Vitamin C, Vitamin B1, Corticosteroids | 22 |
Placebo | 21 |
ICU mortality rate (NCT03389555)
Timeframe: Enrollment until ICU discharge, death, or 30-days. Whichever comes first.
Intervention | Participants (Count of Participants) |
---|---|
Vitamin C, Vitamin B1, Corticosteroids | 23 |
Placebo | 20 |
"Describes if patient has delirium as defined by the Confusion Assessment Method (CAM)-ICU. The CAM-ICU method requires that the patient have 3 features to qualify for delirium:~Acute Onset of Changes or Fluctuations in the Course of Mental Status (AND )~Inattention (AND)~Disorganized thinking (OR) Altered Level of Consciousness" (NCT03389555)
Timeframe: On day 3 (at approximately 72 hours) after the first study drug dose
Intervention | Participants (Count of Participants) |
---|---|
Vitamin C, Vitamin B1, Corticosteroids | 31 |
Placebo | 35 |
"Development of renal failure as defined by a Kidney Disease Improving Global Outcomes [KDIGO] stage 3 or higher. There are 3 stages in the KDIGO scale with stage 3 being the worst (corresponds to renal failure).~Stage 1- serum creatinine 1.5 to 1.9 times baseline OR an increase in serum creatinine ≥ 0.3 mg/dL OR urine output < 0.5ml/kg/hour for 6-12 hours. Stage 2- serum creatinine 2.0-2.9 times baseline OR urine output <0.5mg/kg/hour for ≥ 12 hours Stage 3- serum creatinine 3.0 times baseline (or serum creatinine of more than or equal to 4.0 mg/dl with an acute increase of at least 0.5 mg/dl) (OR) Urine output less than 0.3 ml/kg/hour for 24 hours or anuria for 12 hours or new renal replacement therapy" (NCT03389555)
Timeframe: Enrollment until 7-days or discharge from the ICU
Intervention | Participants (Count of Participants) |
---|---|
Vitamin C, Vitamin B1, Corticosteroids | 32 |
Placebo | 27 |
Days not receiving vasopressor (NCT03389555)
Timeframe: Vasopressor free days over the first 7-days after enrollment
Intervention | Days (Median) |
---|---|
Vitamin C, Vitamin B1, Corticosteroids | 5 |
Placebo | 4 |
Days not receiving invasive mechanical ventilation (NCT03389555)
Timeframe: Ventilator free days over the first 7-days after enrollment
Intervention | Days (Median) |
---|---|
Vitamin C, Vitamin B1, Corticosteroids | 6 |
Placebo | 6 |
Sequential Organ Failure Assessment (SOFA) Score at Baseline and 72 Hours. The SOFA score ranges from a minimum of 0 to a maximum of 24, with higher scores meaning worse outcomes. (NCT03389555)
Timeframe: Enrollment to 72-hours
Intervention | Units on a scale (Mean) | |
---|---|---|
Enrollment SOFA score | 72 hour SOFA score | |
Placebo | 9.2 | 5.1 |
Vitamin C, Vitamin B1, Corticosteroids | 9.1 | 4.4 |
Change in lactate level between enrollment and 72 hours after enrollment (NCT03550794)
Timeframe: From time of enrollment until 72 hours after enrollment
Intervention | mmol/L (Median) |
---|---|
Thiamine | 1.65 |
Placebo | 1.95 |
Change in Sequential Organ Failure Assessment Score (SOFA) score between enrollment and 72 hours after enrollment. SOFA scores are reported on a scale between 0-24, with 0 representing best outcome and 24 representing worst outcome. (NCT03550794)
Timeframe: Time of enrollment until 72 hours after enrollment
Intervention | units on a scale (Mean) |
---|---|
Thiamine | 8.09 |
Placebo | 9.61 |
Days alive and free of the ICU through day 28 (NCT03550794)
Timeframe: From date of enrollment until 28 days after enrollment
Intervention | days (Median) |
---|---|
Thiamine | 22.5 |
Placebo | 0.0 |
Length of hospital stay truncated at 60 days (NCT03550794)
Timeframe: From date of enrollment until discharge from the hospital or date of death, whichever comes first, up to 60 days after enrollment
Intervention | Participants (Count of Participants) |
---|---|
Thiamine | 15 |
Placebo | 25 |
Change in creatinine over time (NCT03550794)
Timeframe: Enrollment to 72-hours
Intervention | mg/dL (Mean) |
---|---|
Thiamine | 2.24 |
Placebo | 2.79 |
Acute renal failure as defined by the KDIGO (Kidney Disease Improving Global Outcomes) AKI (Acute Kidney Injury) criteria. In brief, a patient can meet these criteria if their serum creatinine increases (for example, serum creatinine increases to 1.5x or higher of baseline serum creatinine, or if it crosses 4mg/dL), or if renal replacement therapy is initiated, or if urine output decreases (for example, <0.5ml/kg/hour for 6-12 hours) or if patient becomes anuric (no urine production). (NCT03550794)
Timeframe: From date of enrollment until day of discharge from the index ICU admission or date of death, whichever comes first up until 60 days post-enrollment
Intervention | Participants (Count of Participants) |
---|---|
Thiamine | 23 |
Placebo | 34 |
Number of participants who received renal replacement therapy in thiamine and placebo groups. (NCT03550794)
Timeframe: From date of enrollment until discharge from the intensive care unit (ICU) or date of death, whichever comes first, up to 60 days after enrollment
Intervention | Participants (Count of Participants) |
---|---|
Thiamine | 6 |
Placebo | 10 |
Number of Participants with Delirium on Day 3 after enrollment (NCT03550794)
Timeframe: Day 3 after enrollment
Intervention | Participants (Count of Participants) |
---|---|
Thiamine | 25 |
Placebo | 30 |
KIM-1, NGAL, Cystatin-C at 24-hours after enrollment (NCT03550794)
Timeframe: 24 hours after enrollment
Intervention | pg/mL (Median) | ||
---|---|---|---|
KIM-1 | NGAL | Cystatin | |
Placebo | 793.9 | 1558285.0 | 2183175.4 |
Thiamine | 763.1 | 1067898.2 | 1689158.2 |
3 trials available for thiamine and Acute Kidney Failure
Article | Year |
---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Acute Kidney Injury; Adult; Aged; Albumins; Alloys; Amides; Amino Acids; Animals; Antineoplastic Com | 2023 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid | 2017 |
Copper, selenium, zinc, and thiamine balances during continuous venovenous hemodiafiltration in critically ill patients.
Topics: Acute Kidney Injury; Aged; Copper; Critical Care; Cross-Over Studies; Female; Hemodiafiltration; Hum | 2004 |
13 other studies available for thiamine and Acute Kidney Failure
Article | Year |
---|---|
HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS.
Topics: Acute Kidney Injury; Animals; Ascorbic Acid; Hydrocortisone; Kidney; Mice; Oxidative Stress; Sepsis; | 2022 |
HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS.
Topics: Acute Kidney Injury; Animals; Ascorbic Acid; Hydrocortisone; Kidney; Mice; Oxidative Stress; Sepsis; | 2022 |
HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS.
Topics: Acute Kidney Injury; Animals; Ascorbic Acid; Hydrocortisone; Kidney; Mice; Oxidative Stress; Sepsis; | 2022 |
HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS.
Topics: Acute Kidney Injury; Animals; Ascorbic Acid; Hydrocortisone; Kidney; Mice; Oxidative Stress; Sepsis; | 2022 |
Pentoxifylline and thiamine ameliorate rhabdomyolysis-induced acute kidney injury in rats via suppressing TLR4/NF-κB and NLRP-3/caspase-1/gasdermin mediated-pyroptosis.
Topics: Acute Kidney Injury; Animals; Antioxidants; Caspase 1; Creatinine; Gasdermins; Glycerol; Male; NF-ka | 2023 |
The Key to a Boy's Heart Is Through His Intestine.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Beriberi; Biopsy; Cardiotonic Agents; Child; Colon, Tran | 2020 |
Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality.
Topics: Acute Kidney Injury; Adult; Aged; Animals; Critical Illness; Female; Gluconeogenesis; Glucose; Human | 2020 |
Progressive encephalopathy associated with nutritional deficiencies: Identifying patients at high risk for developing thiamine deficiency.
Topics: Acidosis; Acute Kidney Injury; Delayed Diagnosis; Disease Progression; Duodenitis; Female; Gait Diso | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant | 2017 |
Acute tacrolimus toxicity in a non-transplant patient.
Topics: Acidosis; Acute Kidney Injury; Adult; Female; Half-Life; Humans; Immunosuppressive Agents; Medicatio | 2008 |
[ACUTE RENAL FAILURE FOLLOWING VENOSTASIN TREATMENT].
Topics: Acute Kidney Injury; Aesculus; Drug Combinations; Drug Hypersensitivity; Escin; Injections, Intraven | 1964 |
Beriberi heart disease with acute renal failure.
Topics: Acute Kidney Injury; Adult; Anuria; Beriberi; Erythrocytes; Heart Diseases; Humans; Male; Thiamine; | 1967 |
Measurement of urinary thiamine propyl disulfide metabolites as an index of liver function.
Topics: Acute Kidney Injury; Administration, Oral; Adolescent; Adult; Crohn Disease; Female; Humans; Intesti | 1984 |
[Drug-induced renal lesions].
Topics: Acute Kidney Injury; Adolescent; Adult; Anaphylaxis; Drug Therapy, Combination; Female; Humans; Male | 1983 |
Ethylene glycol ingestion resulting in brainstem and midbrain dysfunction.
Topics: Acute Kidney Injury; Adult; Arrhythmias, Cardiac; Brain Diseases; Brain Edema; Brain Stem; Calcium G | 2000 |
Thiamine deficiency and oxalosis.
Topics: Acute Kidney Injury; Adipates; Adult; Carboxy-Lyases; Diphosphates; Glyoxylates; Humans; Ketoglutari | 1974 |