Page last updated: 2024-10-20

thiamine and Acute Kidney Failure

thiamine has been researched along with Acute Kidney Failure in 16 studies

thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.

Research Excerpts

ExcerptRelevanceReference
"Our results suggest that the early use of intravenous vitamin C, together with corticosteroids and thiamine, are effective in preventing progressive organ dysfunction, including acute kidney injury, and in reducing the mortality of patients with severe sepsis and septic shock."7.85Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study. ( Catravas, J; Hooper, MH; Khangoora, V; Marik, PE; Rivera, R, 2017)
" Since thiamine pyrophosphate is a cofactor in the reaction, thiamine deficiency might be expected to result in tissue oxalosis."7.65Thiamine deficiency and oxalosis. ( Salyer, DC; Salyer, WR, 1974)
"Methods: Sepsis was induced using the cecal ligation and puncture (CLP) model of sepsis with fluid and antibiotic support."5.72HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS. ( Kim, J; Remick, D; Stolarski, A; Wee, K; Zhang, Q, 2022)
"Our results suggest that the early use of intravenous vitamin C, together with corticosteroids and thiamine, are effective in preventing progressive organ dysfunction, including acute kidney injury, and in reducing the mortality of patients with severe sepsis and septic shock."3.85Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study. ( Catravas, J; Hooper, MH; Khangoora, V; Marik, PE; Rivera, R, 2017)
"Ethylene glycol toxicity has produced central nervous system abnormalities including coma, cerebral edema, and cranial nerve dysfunction."3.70Ethylene glycol ingestion resulting in brainstem and midbrain dysfunction. ( Follmer, R; Ford, MD; Morgan, BW, 2000)
" Since thiamine pyrophosphate is a cofactor in the reaction, thiamine deficiency might be expected to result in tissue oxalosis."3.65Thiamine deficiency and oxalosis. ( Salyer, DC; Salyer, WR, 1974)
"Acute renal failure is a serious complication in critically ill patients and frequently requires renal replacement therapy, which alters trace element and vitamin metabolism."2.71Copper, selenium, zinc, and thiamine balances during continuous venovenous hemodiafiltration in critically ill patients. ( Baines, M; Berger, MM; Cayeux, MC; Chioléro, RL; Revelly, JP; Roberts, E; Shenkin, A, 2004)
"Methods: Sepsis was induced using the cecal ligation and puncture (CLP) model of sepsis with fluid and antibiotic support."1.72HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS. ( Kim, J; Remick, D; Stolarski, A; Wee, K; Zhang, Q, 2022)
"Tacrolimus is an immunosuppressant widely used in recipients of solid organ transplants to prevent rejection."1.35Acute tacrolimus toxicity in a non-transplant patient. ( Mowry, J; O'Connor, AD; Rusyniak, DE, 2008)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's3 (18.75)24.3611
2020's5 (31.25)2.80

Authors

AuthorsStudies
Kim, J3
Stolarski, A3
Zhang, Q3
Wee, K3
Remick, D3
Al-Kharashi, L1
Attia, H1
Alsaffi, A1
Almasri, T1
Arafa, M1
Hasan, I1
Alajami, H1
Ali, R1
Badr, A1
Dhanani, LY1
Totton, RR1
Jara-Quijada, E1
Pérez-Won, M1
Tabilo-Munizaga, G1
Lemus-Mondaca, R1
González-Cavieres, L1
Palma-Acevedo, A1
Herrera-Lavados, C1
Milovanovic, S1
Grzegorczyk, A1
Świątek, Ł1
Grzęda, A1
Dębczak, A1
Tyskiewicz, K1
Konkol, M1
Li, Y2
Chang, P1
Sankaran, S1
Jang, H1
Nie, Y1
Zeng, A1
Hussain, S1
Wu, JY1
Chen, X2
Shi, L2
Senapati, A1
Chetri, BK1
Mitra, S1
Shelke, RG1
Rangan, L1
Chauhan, AS1
Tiwari, M1
Indoliya, Y1
Mishra, SK1
Lavania, UC1
Chauhan, PS1
Chakrabarty, D1
Tripathi, RD1
Akaputra, R1
Hatta, M1
Massi, MN1
Djaharuddin, I1
Bukhari, A1
Aminuddin, A1
Santoso, A1
Natzir, R1
Bahar, B1
Fachri, M1
Farsida, F1
Fathimah, A1
Ubaidah, FM1
Sridiana, E1
Dwiyanti, R1
Syukri, A1
Junita, AR1
Febrianti, A1
Primaguna, MR1
Azhar, A1
Rajaure, YS1
Thapa, B1
Budhathoki, L1
Rana, SR1
Khadka, M1
Batchu, UR1
Surapaneni, JR1
Cheemalamarri, C1
Mandava, K1
Puvvada, N1
Shetty, PR1
Mv, S1
Ranjbarian, P1
Goudarzi, F1
Akya, A1
Heidarinia, H1
Farasat, A1
Rostamian, M1
Suri, K1
Rajput, N1
Sharma, P1
Omble, AD1
Kulkarni, K1
Gahlay, GK1
Fernandez Garcia, E1
Paudel, U1
Noji, MC1
Bowman, CE1
Rustgi, AK1
Pitarresi, JR1
Wellen, KE1
Arany, Z1
Weissenrieder, JS1
Foskett, JK1
Lee, MS1
Han, HJ1
Choi, TI1
Lee, KH1
Baasankhuu, A1
Kim, HT1
Kim, CH1
Redd, PS1
Payero, L1
Gilbert, DM1
Page, CA1
King, R1
McAssey, EV1
Bodie, D1
Diaz, S1
Hancock, CN1
Lee, HS1
Jung, S1
Lee, SW1
Kim, YT1
Lee, J1
Ren, T1
Yu, Z1
Yu, H1
Deng, K1
Wang, Z1
Li, X1
Wang, H1
Wang, L2
Xu, Y1
Lascano, J1
Riley, L1
Khodayari, N1
Brantly, M1
Gupta, R1
Pradhan, J1
Haldar, A1
Murapaka, C1
Chandra Mondal, P1
Gao, R1
Dai, TY1
Meng, Z1
Sun, XF1
Liu, DX1
Shi, MM1
Li, HR1
Kang, X1
Bi, B1
Zhang, YT1
Xu, TW1
Yan, JM1
Jiang, Q1
Helmchen, G1
Guo, H1
Xiang, W1
Fang, Y1
Li, J4
Lin, Y1
An, X1
Jiang, D1
Cao, Q1
Xu, F1
Shiigi, H1
Wang, W1
Chen, Z1
Akosman, I1
Kumar, N1
Mortenson, R1
Lans, A1
De La Garza Ramos, R1
Eleswarapu, A1
Yassari, R1
Fourman, MS1
Jana, S1
Evans, EGB1
Jang, HS1
Zhang, S2
Zhang, H1
Rajca, A1
Gordon, SE1
Zagotta, WN1
Stoll, S1
Mehl, RA1
Miller, S1
Lee, DA1
Muhimpundu, S1
Maxwell, CA1
Liu, Z1
Shen, F1
Tong, Q1
Tang, M1
Peng, M1
Jiao, Z1
Jiang, Y1
Ao, L1
Fu, W1
Lv, X1
Jiang, G1
Hou, L1
Tu, WC1
McManamen, AM1
Su, X1
Jeacopello, I1
Takezawa, MG1
Hieber, DL1
Hassan, GW1
Lee, UN1
Anana, EV1
Locknane, MP1
Stephenson, MW1
Shinkawa, VAM1
Wald, ER1
DeMuri, GP1
Adams, KN1
Berthier, E1
Thongpang, S1
Theberge, AB1
Jiang, L1
Li, Z1
Dong, Q1
Rong, X1
Dong, G1
Huang, J1
Liang, Y1
Sun, S1
Zhang, R1
Miao, Z1
Senju, C1
Nakazawa, Y1
Oso, T1
Shimada, M1
Kato, K1
Matsuse, M1
Tsujimoto, M1
Masaki, T1
Miyazaki, Y1
Fukushima, S1
Tateishi, S1
Utani, A1
Murota, H1
Tanaka, K1
Mitsutake, N1
Moriwaki, S1
Nishigori, C1
Ogi, T1
Liu, C1
Zhang, X1
Wang, B1
Luo, Z1
Qian, D1
Liu, J1
Waterhouse, GIN1
Barbosa, M1
Marques-Sá, J1
Carvalho, C1
Fernandes, V1
Grilli, D1
Smetana, V1
Ahmed, SJ1
Shtender, V1
Pani, M1
Manfrinetti, P1
Mudring, AV1
Kuang, Y1
Yang, D1
Gai, S1
He, F1
An, B1
Yang, P1
Notini, L1
Schulz, K1
Kubeneck, LJ1
Grigg, ARC1
Rothwell, KA1
Fantappiè, G1
ThomasArrigo, LK1
Kretzschmar, R1
Siswanto, FM1
Okukawa, K1
Tamura, A1
Oguro, A1
Imaoka, S1
Kim, CG1
Jung, M1
Kim, HS1
Lee, CK1
Jeung, HC1
Koo, DH1
Bae, WK1
Zang, DY1
Kim, BJ1
Kim, H1
Yun, UJ1
Che, J1
Park, S1
Kim, TS1
Kwon, WS1
Park, J1
Cho, SW1
Nam, CM1
Chung, HC1
Rha, SY1
Colombo, N1
Van Gorp, T1
Matulonis, UA1
Oaknin, A1
Grisham, RN1
Fleming, GF1
Olawaiye, AB1
Nguyen, DD1
Greenstein, AE1
Custodio, JM1
Pashova, HI1
Tudor, IC1
Lorusso, D1
Zhou, F1
Jiang, Z1
Liang, H1
Ru, S1
Bettiol, AA1
Gao, W1
Lipsyc-Sharf, M1
Jain, E1
Collins, LC1
Rosenberg, SM1
Ruddy, KJ1
Tamimi, RM1
Schapira, L1
Come, SE1
Peppercorn, JM1
Borges, VF1
Warner, E1
Snow, C1
Krop, IE1
Kim, D1
Weiss, J1
Zanudo, JGT1
Partridge, AH1
Wagle, N1
Waks, AG1
Moskowitz, A2
Berg, KM1
Grossestreuer, AV1
Balaji, L1
Liu, X1
Cocchi, MN2
Chase, M1
Gong, MN1
Gong, J1
Parikh, SM1
Ngo, L1
Berlin, N1
Donnino, MW2
Zhou, Y1
Chen, Q1
Zhong, S1
Liu, H1
Koh, K1
Chen, H1
He, J1
Chen, J1
Liu, S1
Lin, L1
Zhang, Y1
Xiao, S1
Cao, S1
Yan, B2
Deng, J1
Gu, J1
Tao, Y1
Huang, C1
Lai, C1
Yong, Q1
Shen, Y1
Gong, Z1
Cao, J1
Mao, W1
Yao, Y1
Zhao, J1
Li, Q1
Liu, K1
Liu, B1
Feng, S1
Chandran, V1
Kunjan, C1
Veerapandian, V1
Kannan, R1
Zhang, T1
von Gunten, U1
Caruso, FR1
Goulart, CDL1
Jr, JCB1
de Oliveira, CR1
Mendes, RG1
Arena, R1
Borghi-Silva, A1
Carrasco-Nuñes, N1
Romano, M1
Cabeza, M1
Jiang, B1
Chen, D1
Zhao, C1
Ma, Y1
Yang, W1
Shen, X1
Satheeshkumar, K1
Saravanakumar, P1
Kalavathi, A1
Vennila, KN1
Elango, KP1
Mues Genannt Koers, L1
Prevost, D1
Paulssen, E1
Hoehr, C1
Ulhassan, Z1
Yang, S1
He, D1
Khan, AR1
Salam, A1
Azhar, W1
Muhammad, S1
Ali, S1
Hamid, Y1
Khan, I1
Sheteiwy, MS1
Zhou, W1
Wang, X1
Xie, Q1
Wang, Y1
Lü, H1
Fu, M1
Wang, D1
Jazayeri, A1
Nonga, D1
Rao, M1
Legouis, D1
Ricksten, SE1
Faivre, A1
Verissimo, T1
Gariani, K1
Verney, C1
Galichon, P1
Berchtold, L1
Feraille, E1
Fernandez, M1
Placier, S1
Koppitch, K1
Hertig, A1
Martin, PY1
Naesens, M1
Pugin, J1
McMahon, AP1
Cippà, PE1
de Seigneux, S1
Freire-Aragón, MD1
Fernández Delgado, E1
Carbajal-Guerrero, J1
Ribera-Rubiales, G1
Marik, PE1
Khangoora, V1
Rivera, R1
Hooper, MH1
Catravas, J1
Andersen, LW1
Karlsson, M1
Patel, PV1
O'Connor, AD1
Rusyniak, DE1
Mowry, J1
BERNING, H1
Berger, MM1
Shenkin, A1
Revelly, JP1
Roberts, E1
Cayeux, MC1
Baines, M1
Chioléro, RL1
Webb, DI1
Oda, R1
Okumura, M1
Yamano, S1
Yoshimura, H1
Severova, EIa1
Karmysheva, VIa1
Balkarova, OV1
Morgan, BW1
Ford, MD1
Follmer, R1
Salyer, WR1
Salyer, DC1

Clinical Trials (15)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Combined Vitamin C, Stress-dose Steroids, and Thiamine on Cerebral Autoregulation and Functional Outcomes of Patients With Septic Shock[NCT03649633]Phase 1/Phase 2100 participants (Anticipated)Interventional2018-09-06Recruiting
Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock[NCT03828929]Phase 33 participants (Actual)Interventional2019-10-15Terminated (stopped due to Recent similar studies have been completed and published showing no benefit to the intervention.)
Impact of Thiamine Supplementation on Mortality in Septic Shock. A Controlled Before-and-after Study.[NCT05840718]80 participants (Anticipated)Observational2023-09-30Not yet recruiting
Effect of Intravenous Vitamin C on Sequential Organ Failure Assessment (SOFA) Score Among Septic Patients: Randomized Controlled Trial[NCT04137276]33 participants (Actual)Interventional2019-04-01Completed
Early High-dose Vitamin C in Post-cardiac Arrest Syndrome[NCT03509662]Phase 2270 participants (Anticipated)Interventional2019-10-07Recruiting
Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock[NCT03380507]Phase 2/Phase 3106 participants (Actual)Interventional2018-03-17Terminated (stopped due to The research is no longer funded and terminated due to futility)
Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis.[NCT03422159]Phase 2140 participants (Actual)Interventional2018-02-05Completed
Ascorbic Ccid, Hydrocortisone, and Thiamine in Sepsis and Septic Shock - A Randomized, Double-Blind, Placebo-Controlled Trial[NCT03389555]Phase 2/Phase 3205 participants (Actual)Interventional2018-02-09Completed
Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock: a Randomized Clinical Study (VITAMIN TRIAL)[NCT05192213]Phase 31,090 participants (Anticipated)Interventional2021-08-01Recruiting
Combination Therapy of Vitamin C and Thiamine for Septic Shock: Multi-center, Double-blinded, Randomized, Controlled Study[NCT03756220]Phase 2116 participants (Actual)Interventional2018-12-01Completed
A Randomized, Double Blind, Placebo-Controlled Trial to Investigate the Effect of Vitamin C, Hydrocortisone and Thiamine on the Outcome of Patients With Septic Shock[NCT03592693]Phase 2400 participants (Anticipated)Interventional2018-09-06Recruiting
Effects of Vitamin C Administration on Extravascular Lung Water in Patients With Severe Features of Preeclampsia: a Randomized, Placebo-controlled Trial[NCT03451266]Phase 134 participants (Actual)Interventional2018-04-07Completed
A Randomized, Double Blind, Placebo-Controlled Study to Investigate the Effects of Vitamin C, Hydrocortisone and Thiamine on the Outcome of Patients With Severe Sepsis and Septic Shock[NCT03335124]Phase 45 participants (Actual)Interventional2017-09-26Terminated (stopped due to Due to insufficient recruitment)
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock: A Prospective Study[NCT03258684]80 participants (Actual)Interventional2017-09-25Completed
Thiamine as a Renal Protective Agent in Septic Shock: A Randomized, Controlled Study[NCT03550794]Phase 295 participants (Actual)Interventional2018-09-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Sequential Organ Failure Assessment (SOFA) Score

Defined as the day 4 post-randomization SOFA score minus the initial SOFA score. The Sequential Organ Failure Assessment (SOFA) Score is a mortality prediction score that is based on the degree of dysfunction of six organ systems. The score is calculated on admission and every 24 hours until discharge using the worst parameters measured during the prior 24 hours SOFA score ranges from 0 (no organ dysfunction) to 24 (highest possible score / organ dysfunction). (NCT03422159)
Timeframe: 4 days post-randomization

Interventionscore on a scale (Mean)
Treatment Arm2.9
Placebo Arm1.93

Hospital Length of Stay

Time from admitting to discharge of hospital stay. (NCT03422159)
Timeframe: From admission to the hospital until final discharge, up to 28 days.

InterventionDays (Mean)
Treatment Arm11.5
Placebo Arm11

Hospital Mortality

In-hospital mortality rate. (NCT03422159)
Timeframe: Survival until hospital discharge, up to 28 days.

InterventionParticipants (Count of Participants)
Treatment Arm11
Placebo Arm13

ICU Length of Stay

Time from admitting to ICU to discharge. (NCT03422159)
Timeframe: From admission to the ICU until final discharge from the ICU, up to an average of 7 days.

Interventiondays (Mean)
Treatment Arm4.76
Placebo Arm4.66

ICU Mortality

ICU mortality rate (NCT03422159)
Timeframe: From admission to hospital until final discharge from the ICU, up to 28 days.

InterventionParticipants (Count of Participants)
Treatment Arm6
Placebo Arm10

Procalcitonin (PCT) Clearance

PCT at 96 hours minus initial PCT, divided by the initial PCT multiplied by 100. (NCT03422159)
Timeframe: 4 days post-randomization

InterventionPercent (Mean)
Treatment Arm63
Placebo Arm58

Time to Vasopressor Independence (Hours)

Defined as the time from starting the active treatment/placebo to discontinuation of all pressors. (NCT03422159)
Timeframe: From start of vasopressor medication to final discontinuation of vasopressor medication, up to 7 days.

Interventionhours (Mean)
HAT Treatment27
Comparator53

Ventilator Free Days

Number of days alive and off of the ventilator at day 28. (NCT03422159)
Timeframe: 28 Days post-randomization

InterventionDays (Mean)
Treatment Arm22
Placebo Arm22.4

30-day Mortality

Mortality rate (NCT03389555)
Timeframe: Enrollment until 30-days after enrollment

InterventionParticipants (Count of Participants)
Vitamin C, Vitamin B1, Corticosteroids35
Placebo29

Hospital Disposition: Survivors Discharged Home

Home hospital disposition in patients who survive to discharge (NCT03389555)
Timeframe: Enrollment until hospital discharge, death, or 30-days, whichever comes first.

InterventionParticipants (Count of Participants)
Vitamin C, Vitamin B1, Corticosteroids34
Placebo35

Hospital Mortality

Hospital mortality rate (NCT03389555)
Timeframe: Enrollment until hospital discharge, death, or 30-days. Whichever comes first.

InterventionParticipants (Count of Participants)
Vitamin C, Vitamin B1, Corticosteroids28
Placebo23

ICU Free Days

Number of days that the patient was not in the ICU. Timeframe listed below. (NCT03389555)
Timeframe: From enrollment until 28 days after enrollment

InterventionDays (Median)
Vitamin C, Vitamin B1, Corticosteroids22
Placebo21

Intensive Care Unit (ICU) Mortality

ICU mortality rate (NCT03389555)
Timeframe: Enrollment until ICU discharge, death, or 30-days. Whichever comes first.

InterventionParticipants (Count of Participants)
Vitamin C, Vitamin B1, Corticosteroids23
Placebo20

Number of Participants With Delirium

"Describes if patient has delirium as defined by the Confusion Assessment Method (CAM)-ICU. The CAM-ICU method requires that the patient have 3 features to qualify for delirium:~Acute Onset of Changes or Fluctuations in the Course of Mental Status (AND )~Inattention (AND)~Disorganized thinking (OR) Altered Level of Consciousness" (NCT03389555)
Timeframe: On day 3 (at approximately 72 hours) after the first study drug dose

InterventionParticipants (Count of Participants)
Vitamin C, Vitamin B1, Corticosteroids31
Placebo35

Renal Failure

"Development of renal failure as defined by a Kidney Disease Improving Global Outcomes [KDIGO] stage 3 or higher. There are 3 stages in the KDIGO scale with stage 3 being the worst (corresponds to renal failure).~Stage 1- serum creatinine 1.5 to 1.9 times baseline OR an increase in serum creatinine ≥ 0.3 mg/dL OR urine output < 0.5ml/kg/hour for 6-12 hours. Stage 2- serum creatinine 2.0-2.9 times baseline OR urine output <0.5mg/kg/hour for ≥ 12 hours Stage 3- serum creatinine 3.0 times baseline (or serum creatinine of more than or equal to 4.0 mg/dl with an acute increase of at least 0.5 mg/dl) (OR) Urine output less than 0.3 ml/kg/hour for 24 hours or anuria for 12 hours or new renal replacement therapy" (NCT03389555)
Timeframe: Enrollment until 7-days or discharge from the ICU

InterventionParticipants (Count of Participants)
Vitamin C, Vitamin B1, Corticosteroids32
Placebo27

Shock Free Days

Days not receiving vasopressor (NCT03389555)
Timeframe: Vasopressor free days over the first 7-days after enrollment

InterventionDays (Median)
Vitamin C, Vitamin B1, Corticosteroids5
Placebo4

Ventilator Free Days

Days not receiving invasive mechanical ventilation (NCT03389555)
Timeframe: Ventilator free days over the first 7-days after enrollment

InterventionDays (Median)
Vitamin C, Vitamin B1, Corticosteroids6
Placebo6

Sequential Organ Failure Assessment (SOFA) Score at Baseline and 72 Hours

Sequential Organ Failure Assessment (SOFA) Score at Baseline and 72 Hours. The SOFA score ranges from a minimum of 0 to a maximum of 24, with higher scores meaning worse outcomes. (NCT03389555)
Timeframe: Enrollment to 72-hours

,
InterventionUnits on a scale (Mean)
Enrollment SOFA score72 hour SOFA score
Placebo9.25.1
Vitamin C, Vitamin B1, Corticosteroids9.14.4

Change in Lactate Level

Change in lactate level between enrollment and 72 hours after enrollment (NCT03550794)
Timeframe: From time of enrollment until 72 hours after enrollment

Interventionmmol/L (Median)
Thiamine1.65
Placebo1.95

Change in the Sequential Organ Failure Assessment Score

Change in Sequential Organ Failure Assessment Score (SOFA) score between enrollment and 72 hours after enrollment. SOFA scores are reported on a scale between 0-24, with 0 representing best outcome and 24 representing worst outcome. (NCT03550794)
Timeframe: Time of enrollment until 72 hours after enrollment

Interventionunits on a scale (Mean)
Thiamine8.09
Placebo9.61

ICU Free Days

Days alive and free of the ICU through day 28 (NCT03550794)
Timeframe: From date of enrollment until 28 days after enrollment

Interventiondays (Median)
Thiamine22.5
Placebo0.0

In-hospital Mortality

Length of hospital stay truncated at 60 days (NCT03550794)
Timeframe: From date of enrollment until discharge from the hospital or date of death, whichever comes first, up to 60 days after enrollment

InterventionParticipants (Count of Participants)
Thiamine15
Placebo25

Kidney Injury Biomarker

Change in creatinine over time (NCT03550794)
Timeframe: Enrollment to 72-hours

Interventionmg/dL (Mean)
Thiamine2.24
Placebo2.79

Number of Participants Experiences Acute Renal Failure

Acute renal failure as defined by the KDIGO (Kidney Disease Improving Global Outcomes) AKI (Acute Kidney Injury) criteria. In brief, a patient can meet these criteria if their serum creatinine increases (for example, serum creatinine increases to 1.5x or higher of baseline serum creatinine, or if it crosses 4mg/dL), or if renal replacement therapy is initiated, or if urine output decreases (for example, <0.5ml/kg/hour for 6-12 hours) or if patient becomes anuric (no urine production). (NCT03550794)
Timeframe: From date of enrollment until day of discharge from the index ICU admission or date of death, whichever comes first up until 60 days post-enrollment

InterventionParticipants (Count of Participants)
Thiamine23
Placebo34

Number of Participants Receiving Renal Replacement Therapy

Number of participants who received renal replacement therapy in thiamine and placebo groups. (NCT03550794)
Timeframe: From date of enrollment until discharge from the intensive care unit (ICU) or date of death, whichever comes first, up to 60 days after enrollment

InterventionParticipants (Count of Participants)
Thiamine6
Placebo10

Number of Participants With Delirium on Day 3

Number of Participants with Delirium on Day 3 after enrollment (NCT03550794)
Timeframe: Day 3 after enrollment

InterventionParticipants (Count of Participants)
Thiamine25
Placebo30

Novel Biomarkers of Renal Injury

KIM-1, NGAL, Cystatin-C at 24-hours after enrollment (NCT03550794)
Timeframe: 24 hours after enrollment

,
Interventionpg/mL (Median)
KIM-1NGALCystatin
Placebo793.91558285.02183175.4
Thiamine763.11067898.21689158.2

Trials

3 trials available for thiamine and Acute Kidney Failure

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Sexuality research & social policy : journal of NSRC : SR & SP, 2023, Apr-05

    Topics: Acute Kidney Injury; Adult; Aged; Albumins; Alloys; Amides; Amino Acids; Animals; Antineoplastic Com

2023
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Thiamine as a Renal Protective Agent in Septic Shock. A Secondary Analysis of a Randomized, Double-Blind, Placebo-controlled Trial.
    Annals of the American Thoracic Society, 2017, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Creatinine; Double-Blind Method; Female; Humans; Kidney; Male; Mid

2017
Copper, selenium, zinc, and thiamine balances during continuous venovenous hemodiafiltration in critically ill patients.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:2

    Topics: Acute Kidney Injury; Aged; Copper; Critical Care; Cross-Over Studies; Female; Hemodiafiltration; Hum

2004

Other Studies

13 other studies available for thiamine and Acute Kidney Failure

ArticleYear
HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS.
    Shock (Augusta, Ga.), 2022, 11-01, Volume: 58, Issue:5

    Topics: Acute Kidney Injury; Animals; Ascorbic Acid; Hydrocortisone; Kidney; Mice; Oxidative Stress; Sepsis;

2022
HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS.
    Shock (Augusta, Ga.), 2022, 11-01, Volume: 58, Issue:5

    Topics: Acute Kidney Injury; Animals; Ascorbic Acid; Hydrocortisone; Kidney; Mice; Oxidative Stress; Sepsis;

2022
HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS.
    Shock (Augusta, Ga.), 2022, 11-01, Volume: 58, Issue:5

    Topics: Acute Kidney Injury; Animals; Ascorbic Acid; Hydrocortisone; Kidney; Mice; Oxidative Stress; Sepsis;

2022
HYDROCORTISONE, ASCORBIC ACID, AND THIAMINE THERAPY DECREASE RENAL OXIDATIVE STRESS AND ACUTE KIDNEY INJURY IN MURINE SEPSIS.
    Shock (Augusta, Ga.), 2022, 11-01, Volume: 58, Issue:5

    Topics: Acute Kidney Injury; Animals; Ascorbic Acid; Hydrocortisone; Kidney; Mice; Oxidative Stress; Sepsis;

2022
Pentoxifylline and thiamine ameliorate rhabdomyolysis-induced acute kidney injury in rats via suppressing TLR4/NF-κB and NLRP-3/caspase-1/gasdermin mediated-pyroptosis.
    Toxicology and applied pharmacology, 2023, 02-15, Volume: 461

    Topics: Acute Kidney Injury; Animals; Antioxidants; Caspase 1; Creatinine; Gasdermins; Glycerol; Male; NF-ka

2023
The Key to a Boy's Heart Is Through His Intestine.
    Gastroenterology, 2020, Volume: 158, Issue:5

    Topics: Acute Kidney Injury; Anti-Bacterial Agents; Beriberi; Biopsy; Cardiotonic Agents; Child; Colon, Tran

2020
Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality.
    Nature metabolism, 2020, Volume: 2, Issue:8

    Topics: Acute Kidney Injury; Adult; Aged; Animals; Critical Illness; Female; Gluconeogenesis; Glucose; Human

2020
Progressive encephalopathy associated with nutritional deficiencies: Identifying patients at high risk for developing thiamine deficiency.
    Medicina intensiva, 2017, Volume: 41, Issue:7

    Topics: Acidosis; Acute Kidney Injury; Delayed Diagnosis; Disease Progression; Duodenitis; Female; Gait Diso

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents; Antioxidant

2017
Acute tacrolimus toxicity in a non-transplant patient.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:9

    Topics: Acidosis; Acute Kidney Injury; Adult; Female; Half-Life; Humans; Immunosuppressive Agents; Medicatio

2008
[ACUTE RENAL FAILURE FOLLOWING VENOSTASIN TREATMENT].
    Deutsche medizinische Wochenschrift (1946), 1964, Aug-14, Volume: 89

    Topics: Acute Kidney Injury; Aesculus; Drug Combinations; Drug Hypersensitivity; Escin; Injections, Intraven

1964
Beriberi heart disease with acute renal failure.
    Archives of internal medicine, 1967, Volume: 120, Issue:4

    Topics: Acute Kidney Injury; Adult; Anuria; Beriberi; Erythrocytes; Heart Diseases; Humans; Male; Thiamine;

1967
Measurement of urinary thiamine propyl disulfide metabolites as an index of liver function.
    International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:11

    Topics: Acute Kidney Injury; Administration, Oral; Adolescent; Adult; Crohn Disease; Female; Humans; Intesti

1984
[Drug-induced renal lesions].
    Sovetskaia meditsina, 1983, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Adult; Anaphylaxis; Drug Therapy, Combination; Female; Humans; Male

1983
Ethylene glycol ingestion resulting in brainstem and midbrain dysfunction.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:4

    Topics: Acute Kidney Injury; Adult; Arrhythmias, Cardiac; Brain Diseases; Brain Edema; Brain Stem; Calcium G

2000
Thiamine deficiency and oxalosis.
    Journal of clinical pathology, 1974, Volume: 27, Issue:7

    Topics: Acute Kidney Injury; Adipates; Adult; Carboxy-Lyases; Diphosphates; Glyoxylates; Humans; Ketoglutari

1974