thiabendazole has been researched along with Abnormalities, Drug-Induced in 8 studies
Tresaderm: dermatologic soln containing dexamethasone, thiabendazole & neomycin sulfate
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition growth and development might also be affected by long-term intake of lead, fluorides or PCBs." | 2.38 | Prenatal risks deriving from environmental chemicals. ( Macrì, C; Mantovani, A; Ricciardi, C; Stazi, AV, 1993) |
| "Thiabendazole (TBZ) is a potent anthelmintic and fungicide used in the treatment of parasitic infections in humans and domestic animals and post-harvest protection of agricultural commodities." | 1.31 | Developmental toxicity of orally administered thiabendazole in ICR mice. ( Ban, Y; Komatsu, T; Lankas, GR; Matsumoto, H; Nakatsuka, T, 2001) |
| " One hr later they were dosed orally with 0, 250, 500 or 1000 mg TBZ/kg." | 1.28 | Glutathione and cysteine enhance and diethylmaleate reduces thiabendazole teratogenicity in mice. ( Fujitani, T; Ogata, A; Sasaki, M; Suzuki, K; Yoneyama, M, 1989) |
| "To study the effects of SKF-525A, an inhibitor of cytochrome P-450, and of sodium phenobarbital (PB), a drug-metabolizing enzyme inducer, on the teratogenicity of thiabendazole (TBZ), pregnant mice were given ip either a single dose of 40 mg SKF-525A/kg 1 hr before oral dosing with 250 or 500 mg TBZ/kg or a dose of 75 mg PB/kg/day on three consecutive days before oral administration of a dose of 500 or 1000 mg TBZ/kg." | 1.27 | Effects of pretreatment with SKF-525A or sodium phenobarbital on thiabendazole-induced teratogenicity in ICR mice. ( Imamichi, T; Ogata, A; Sasaki, M; Suzuki, K; Yoneyama, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mantovani, A | 1 |
| Ricciardi, C | 1 |
| Macrì, C | 1 |
| Stazi, AV | 1 |
| Lankas, GR | 2 |
| Wise, DL | 1 |
| Nakatsuka, T | 1 |
| Ban, Y | 1 |
| Komatsu, T | 1 |
| Matsumoto, H | 1 |
| Ogata, A | 3 |
| Fujitani, T | 1 |
| Yoneyama, M | 3 |
| Sasaki, M | 2 |
| Suzuki, K | 2 |
| Imamichi, T | 1 |
| Tsuchiya, T | 1 |
| Tanaka, A | 1 |
| Hiraga, K | 1 |
| Szabo, KT | 1 |
| Miller, CR | 1 |
| Scott, GC | 1 |
1 review available for thiabendazole and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Prenatal risks deriving from environmental chemicals.
Topics: Abnormalities, Drug-Induced; Animals; Disease Outbreaks; Embryonic and Fetal Development; Environmen | 1993 |
7 other studies available for thiabendazole and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Developmental toxicity of orally administered thiabendazole in Sprague-Dawley rats and New Zealand white rabbits.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Body Weight; Female; Fetal Death; Fetal | 1993 |
Developmental toxicity of orally administered thiabendazole in ICR mice.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Antinematodal Agents; Body Weight; Dose- | 2001 |
Glutathione and cysteine enhance and diethylmaleate reduces thiabendazole teratogenicity in mice.
Topics: Abnormalities, Drug-Induced; Animals; Chromatography, High Pressure Liquid; Cysteine; Drug Interacti | 1989 |
Effects of pretreatment with SKF-525A or sodium phenobarbital on thiabendazole-induced teratogenicity in ICR mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Bone and Bones; Female; Fetal Resorption; Male; M | 1987 |
Effects of thiabendazole on the mouse limb-bud organ and cell in culture.
Topics: Abnormalities, Drug-Induced; Animals; DNA; Embryo, Mammalian; Female; Limb Deformities, Congenital; | 1986 |
Irreversible in vivo binding of thiabendazole to macromolecules in pregnant mice and its relation to teratogenicity.
Topics: Abnormalities, Drug-Induced; Animals; Carbon Radioisotopes; Dose-Response Relationship, Drug; Embryo | 1985 |
The effects of methyl-5(6)-butyl-2-benzimidazole carbamate (parbendazole) on reproduction in sheep and other animals. II. Teratological study in ewes in the United States.
Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Administration, Oral; Animals; Anthelmi | 1974 |