Page last updated: 2024-10-22

theophylline and Uremia

theophylline has been researched along with Uremia in 16 studies

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
" Dose-response curves with the characterized compounds revealed that the most important role in binding inhibition could be attributed to hippuric acid and CMPF."1.30Study by means of high-performance liquid chromatography of solutes that decrease theophylline/protein binding in the serum of uremic patients. ( De Smet, R; Lameire, N; Van Kaer, J; Vanholder, R; Vogeleere, P, 1999)
"Dyphylline (1000 mg) was administered to each patient orally 2 hr before hemodialysis."1.26Pharmacokinetics of dyphylline elimination by uremic patients. ( Lee, CC; Majeske, BL; Marbury, TC; Wang, LH, 1981)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199011 (68.75)18.7374
1990's4 (25.00)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reiter, K1
Bordoni, V1
Dall'Olio, G1
Ricatti, MG1
Soli, M1
Ruperti, S1
Soffiati, G1
Galloni, E1
D'Intini, V1
Bellomo, R1
Ronco, C1
Opheim, KE1
Ainardi, V1
Raisys, VA1
Toseland, PA1
Wicks, JF1
Newall, RG1
Patel, JA1
Clayton, LT1
LeBel, CP1
McClatchey, KD1
Nelson, KM1
Mathews, SE1
Bowers, LD1
Lee, CC1
Wang, LH1
Majeske, BL1
Marbury, TC2
De Smet, R3
Vogeleere, P2
Van Kaer, J2
Lameire, N2
Vanholder, R3
Lee, CS1
Perrin, JH1
Fuller, TJ1
Sterzel, RB1
Vanholder, RC1
De Smet, RV1
Ringoir, SM1
Hoffman, A1
Levy, G1
Benigni, A1
Livio, M1
Dodesini, P1
Schieppati, A1
Panigada, M1
Mecca, G1
de Gaetano, G1
Remuzzi, G1
Van Landschoot, N1
Schoots, A1
Ringoir, S1
Compton, R1
Lichti, D1
Ladenson, JH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Cytokine Adsorption in Severe, Refractory Septic Shock[NCT04910893]48 participants (Actual)Interventional2014-11-27Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

16 other studies available for theophylline and Uremia

ArticleYear
In vitro removal of therapeutic drugs with a novel adsorbent system.
    Blood purification, 2002, Volume: 20, Issue:4

    Topics: Adsorption; Anti-Bacterial Agents; Biocompatible Materials; Carbamazepine; Digoxin; Glycopeptides; H

2002
Increase in apparent theophylline concentration in the serum of two patients as measured by some immunoassay methods (caused by 1,3-dimethyluric acid?)
    Clinical chemistry, 1983, Volume: 29, Issue:9

    Topics: Chromatography, High Pressure Liquid; False Positive Reactions; Humans; Immunoenzyme Techniques; Rea

1983
Application of substrate-labelled fluorescent immunoassay to the measurement of anticonvulsant and antiasthmatic drug levels in plasma and serum.
    Therapeutic drug monitoring, 1983, Volume: 5, Issue:4

    Topics: Anticonvulsants; Asthma; Fluorescent Antibody Technique; Humans; Plasma; Theophylline; Uremia

1983
Abnormal theophylline levels in plasma by fluorescence polarization immunoassay in patients with renal disease.
    Therapeutic drug monitoring, 1984, Volume: 6, Issue:4

    Topics: Blood Urea Nitrogen; Chromatography, High Pressure Liquid; Creatine; Fluorescence Polarization; Huma

1984
Theophylline concentrations may be falsely high in serum of uremic patients.
    Clinical chemistry, 1983, Volume: 29, Issue:12

    Topics: Chromatography, High Pressure Liquid; False Positive Reactions; Female; Humans; Immunoassay; Theophy

1983
Pharmacokinetics of dyphylline elimination by uremic patients.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:2

    Topics: Adult; Aged; Dyphylline; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; R

1981
Study by means of high-performance liquid chromatography of solutes that decrease theophylline/protein binding in the serum of uremic patients.
    Journal of chromatography. A, 1999, Jun-25, Volume: 847, Issue:1-2

    Topics: Blood Proteins; Case-Control Studies; Chromatography, High Pressure Liquid; Dose-Response Relationsh

1999
Identification by HPLC of uraemic retention solutes decreasing theophylline protein binding.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14 Suppl 4

    Topics: Chromatography, High Pressure Liquid; Humans; Protein Binding; Theophylline; Uremia

1999
Hemodialysis of theophylline in uremic patients.
    Journal of clinical pharmacology, 1979, Volume: 19, Issue:4

    Topics: Adult; Aged; Female; Humans; Kinetics; Male; Middle Aged; Renal Dialysis; Theophylline; Time Factors

1979
[Treatment of reversible, uremia-inducing factors in chronic interstitial nephritis].
    Deutsche medizinische Wochenschrift (1946), 1975, Feb-07, Volume: 100, Issue:6

    Topics: Blood Volume; Central Venous Pressure; Chronic Disease; Furosemide; Humans; Kidney; Nephritis, Inter

1975
Assessment of urea and other uremic markers for quantification of dialysis efficacy.
    Clinical chemistry, 1992, Volume: 38, Issue:8 Pt 1

    Topics: Chromatography, High Pressure Liquid; Hemofiltration; Hippurates; Humans; Protein Binding; Regressio

1992
Kinetics of drug action in disease states. XL. Effect of the dialyzable component(s) of uremic blood on theophylline neurotoxicity in rats.
    Pharmaceutical research, 1991, Volume: 8, Issue:3

    Topics: Acute Kidney Injury; Animals; Central Nervous System; Creatinine; Kidney; Male; Rats; Rats, Inbred L

1991
Inhibition of human platelet aggregation by parathyroid hormone. Is cyclic AMP implicated?
    American journal of nephrology, 1985, Volume: 5, Issue:4

    Topics: Adenylyl Cyclases; Blood Platelets; Calcimycin; Calcium; Cyclic AMP; Humans; In Vitro Techniques; Pa

1985
Drug protein binding in chronic renal failure: evaluation of nine drugs.
    Kidney international, 1988, Volume: 33, Issue:5

    Topics: Blood Proteins; Chromatography, High Pressure Liquid; Humans; Kidney Failure, Chronic; Pharmaceutica

1988
Influence of uremia on four assays for theophylline: improved results with a monoclonal antibody in the TDx procedure.
    Clinical chemistry, 1985, Volume: 31, Issue:1

    Topics: Antibodies, Monoclonal; Autoanalysis; Fluorescence Polarization; Humans; Immunoassay; Immunoenzyme T

1985
Positive interference with immunoassay of theophylline in serum of uremics.
    Clinical chemistry, 1985, Volume: 31, Issue:9

    Topics: False Positive Reactions; Humans; Methods; Theophylline; Uremia

1985