theophylline has been researched along with Uremia in 16 studies
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response curves with the characterized compounds revealed that the most important role in binding inhibition could be attributed to hippuric acid and CMPF." | 1.30 | Study by means of high-performance liquid chromatography of solutes that decrease theophylline/protein binding in the serum of uremic patients. ( De Smet, R; Lameire, N; Van Kaer, J; Vanholder, R; Vogeleere, P, 1999) |
| "Dyphylline (1000 mg) was administered to each patient orally 2 hr before hemodialysis." | 1.26 | Pharmacokinetics of dyphylline elimination by uremic patients. ( Lee, CC; Majeske, BL; Marbury, TC; Wang, LH, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (68.75) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reiter, K | 1 |
| Bordoni, V | 1 |
| Dall'Olio, G | 1 |
| Ricatti, MG | 1 |
| Soli, M | 1 |
| Ruperti, S | 1 |
| Soffiati, G | 1 |
| Galloni, E | 1 |
| D'Intini, V | 1 |
| Bellomo, R | 1 |
| Ronco, C | 1 |
| Opheim, KE | 1 |
| Ainardi, V | 1 |
| Raisys, VA | 1 |
| Toseland, PA | 1 |
| Wicks, JF | 1 |
| Newall, RG | 1 |
| Patel, JA | 1 |
| Clayton, LT | 1 |
| LeBel, CP | 1 |
| McClatchey, KD | 1 |
| Nelson, KM | 1 |
| Mathews, SE | 1 |
| Bowers, LD | 1 |
| Lee, CC | 1 |
| Wang, LH | 1 |
| Majeske, BL | 1 |
| Marbury, TC | 2 |
| De Smet, R | 3 |
| Vogeleere, P | 2 |
| Van Kaer, J | 2 |
| Lameire, N | 2 |
| Vanholder, R | 3 |
| Lee, CS | 1 |
| Perrin, JH | 1 |
| Fuller, TJ | 1 |
| Sterzel, RB | 1 |
| Vanholder, RC | 1 |
| De Smet, RV | 1 |
| Ringoir, SM | 1 |
| Hoffman, A | 1 |
| Levy, G | 1 |
| Benigni, A | 1 |
| Livio, M | 1 |
| Dodesini, P | 1 |
| Schieppati, A | 1 |
| Panigada, M | 1 |
| Mecca, G | 1 |
| de Gaetano, G | 1 |
| Remuzzi, G | 1 |
| Van Landschoot, N | 1 |
| Schoots, A | 1 |
| Ringoir, S | 1 |
| Compton, R | 1 |
| Lichti, D | 1 |
| Ladenson, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cytokine Adsorption in Severe, Refractory Septic Shock[NCT04910893] | 48 participants (Actual) | Interventional | 2014-11-27 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 other studies available for theophylline and Uremia
| Article | Year |
|---|---|
In vitro removal of therapeutic drugs with a novel adsorbent system.
Topics: Adsorption; Anti-Bacterial Agents; Biocompatible Materials; Carbamazepine; Digoxin; Glycopeptides; H | 2002 |
Increase in apparent theophylline concentration in the serum of two patients as measured by some immunoassay methods (caused by 1,3-dimethyluric acid?)
Topics: Chromatography, High Pressure Liquid; False Positive Reactions; Humans; Immunoenzyme Techniques; Rea | 1983 |
Application of substrate-labelled fluorescent immunoassay to the measurement of anticonvulsant and antiasthmatic drug levels in plasma and serum.
Topics: Anticonvulsants; Asthma; Fluorescent Antibody Technique; Humans; Plasma; Theophylline; Uremia | 1983 |
Abnormal theophylline levels in plasma by fluorescence polarization immunoassay in patients with renal disease.
Topics: Blood Urea Nitrogen; Chromatography, High Pressure Liquid; Creatine; Fluorescence Polarization; Huma | 1984 |
Theophylline concentrations may be falsely high in serum of uremic patients.
Topics: Chromatography, High Pressure Liquid; False Positive Reactions; Female; Humans; Immunoassay; Theophy | 1983 |
Pharmacokinetics of dyphylline elimination by uremic patients.
Topics: Adult; Aged; Dyphylline; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; R | 1981 |
Study by means of high-performance liquid chromatography of solutes that decrease theophylline/protein binding in the serum of uremic patients.
Topics: Blood Proteins; Case-Control Studies; Chromatography, High Pressure Liquid; Dose-Response Relationsh | 1999 |
Identification by HPLC of uraemic retention solutes decreasing theophylline protein binding.
Topics: Chromatography, High Pressure Liquid; Humans; Protein Binding; Theophylline; Uremia | 1999 |
Hemodialysis of theophylline in uremic patients.
Topics: Adult; Aged; Female; Humans; Kinetics; Male; Middle Aged; Renal Dialysis; Theophylline; Time Factors | 1979 |
[Treatment of reversible, uremia-inducing factors in chronic interstitial nephritis].
Topics: Blood Volume; Central Venous Pressure; Chronic Disease; Furosemide; Humans; Kidney; Nephritis, Inter | 1975 |
Assessment of urea and other uremic markers for quantification of dialysis efficacy.
Topics: Chromatography, High Pressure Liquid; Hemofiltration; Hippurates; Humans; Protein Binding; Regressio | 1992 |
Kinetics of drug action in disease states. XL. Effect of the dialyzable component(s) of uremic blood on theophylline neurotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Central Nervous System; Creatinine; Kidney; Male; Rats; Rats, Inbred L | 1991 |
Inhibition of human platelet aggregation by parathyroid hormone. Is cyclic AMP implicated?
Topics: Adenylyl Cyclases; Blood Platelets; Calcimycin; Calcium; Cyclic AMP; Humans; In Vitro Techniques; Pa | 1985 |
Drug protein binding in chronic renal failure: evaluation of nine drugs.
Topics: Blood Proteins; Chromatography, High Pressure Liquid; Humans; Kidney Failure, Chronic; Pharmaceutica | 1988 |
Influence of uremia on four assays for theophylline: improved results with a monoclonal antibody in the TDx procedure.
Topics: Antibodies, Monoclonal; Autoanalysis; Fluorescence Polarization; Humans; Immunoassay; Immunoenzyme T | 1985 |
Positive interference with immunoassay of theophylline in serum of uremics.
Topics: False Positive Reactions; Humans; Methods; Theophylline; Uremia | 1985 |