Page last updated: 2024-10-22

theophylline and Stroke

theophylline has been researched along with Stroke in 13 studies

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
"The relative cerebral blood flow (rCBF), relative cerebral blood volume (rCBV), and relative mean transit time (rMTT) in the infarct core, penumbra, and unaffected tissue were measured using multi-parametric MRI at baseline and 3‑h follow-up in patients treated with theophylline or placebo as an add-on to thrombolytic therapy."9.51Perfusion Changes in Acute Stroke Treated with Theophylline as an Add-on to Thrombolysis : A Randomized Clinical Trial Subgroup Analysis. ( Andersen, G; Fiehler, J; Forkert, ND; Hjort, N; Modrau, B; Nygård Johansen, M; Vorum, H; Winder, A, 2022)
"We assessed the effect of single-dose theophylline on intracortical and interhemispheric inhibition in patients with chronic stroke, in a double-blind, placebo-controlled, cross-over study."9.22The neurophysiological effects of single-dose theophylline in patients with chronic stroke: A double-blind, placebo-controlled, randomized cross-over study. ( Boehme, AK; Lazar, RM; Marshall, RS; Martinez-Hernandez, IE; Schambra, HM; Slane, KJ, 2016)
"The objective of this review was to assess the effect of theophylline and its analogues, aminophylline and caffeine, in people with confirmed or presumed acute ischaemic stroke."8.82Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke. ( Bath, PM, 2004)
"The objective of this review was to assess the effect of theophylline and its analogues (aminophylline and caffeine) in people with confirmed or presumed acute ischaemic stroke."8.80Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke. ( Bath, FJ; Bath, PM; Mohiuddin, AA, 2000)
"The TEA-Stroke trial (The Theophylline in Acute Ischemic Stroke) was an investigator-initiated 2-center, proof-of-concept, phase II clinical study with a randomized, double-blinded, placebo-controlled design."7.96Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial. ( Andersen, G; Bach, FW; Eskildsen, HW; Hansen, MB; Hjort, N; Johansen, MB; Mikkelsen, IK; Modrau, B; Mouridsen, K; Nielsen, A; Povlsen, JP; Yavarian, Y; Østergaard, L, 2020)
"The relative cerebral blood flow (rCBF), relative cerebral blood volume (rCBV), and relative mean transit time (rMTT) in the infarct core, penumbra, and unaffected tissue were measured using multi-parametric MRI at baseline and 3‑h follow-up in patients treated with theophylline or placebo as an add-on to thrombolytic therapy."5.51Perfusion Changes in Acute Stroke Treated with Theophylline as an Add-on to Thrombolysis : A Randomized Clinical Trial Subgroup Analysis. ( Andersen, G; Fiehler, J; Forkert, ND; Hjort, N; Modrau, B; Nygård Johansen, M; Vorum, H; Winder, A, 2022)
"We assessed the effect of single-dose theophylline on intracortical and interhemispheric inhibition in patients with chronic stroke, in a double-blind, placebo-controlled, cross-over study."5.22The neurophysiological effects of single-dose theophylline in patients with chronic stroke: A double-blind, placebo-controlled, randomized cross-over study. ( Boehme, AK; Lazar, RM; Marshall, RS; Martinez-Hernandez, IE; Schambra, HM; Slane, KJ, 2016)
"The objective of this review was to assess the effect of theophylline and its analogues, aminophylline and caffeine, in people with confirmed or presumed acute ischaemic stroke."4.82Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke. ( Bath, PM, 2004)
"The objective of this review was to assess the effect of theophylline and its analogues (aminophylline and caffeine) in people with confirmed or presumed acute ischaemic stroke."4.80Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke. ( Bath, FJ; Bath, PM; Mohiuddin, AA, 2000)
"The TEA-Stroke trial (The Theophylline in Acute Ischemic Stroke) was an investigator-initiated 2-center, proof-of-concept, phase II clinical study with a randomized, double-blinded, placebo-controlled design."3.96Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial. ( Andersen, G; Bach, FW; Eskildsen, HW; Hansen, MB; Hjort, N; Johansen, MB; Mikkelsen, IK; Modrau, B; Mouridsen, K; Nielsen, A; Povlsen, JP; Yavarian, Y; Østergaard, L, 2020)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19908 (61.54)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's1 (7.69)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Modrau, B2
Andersen, G2
Mikkelsen, IK1
Nielsen, A1
Hansen, MB1
Johansen, MB1
Eskildsen, HW1
Povlsen, JP1
Yavarian, Y1
Mouridsen, K1
Østergaard, L1
Bach, FW1
Hjort, N2
Winder, A1
Nygård Johansen, M1
Fiehler, J1
Vorum, H1
Forkert, ND1
Schambra, HM1
Martinez-Hernandez, IE1
Slane, KJ1
Boehme, AK1
Marshall, RS1
Lazar, RM1
SACINO, G1
ERLEY, E1
EICHHORN, O1
SLADKI, E1
PRUSINSKI, A1
DORNAUS, W1
PUFFER, E1
FREUNDT, KJ1
FRUHMANN, H1
MUELLER, WK1
Bath, PM2
Mohiuddin, AA1
Bath, FJ1

Reviews

2 reviews available for theophylline and Stroke

ArticleYear
Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke.
    The Cochrane database of systematic reviews, 2004, Issue:3

    Topics: Aminophylline; Brain Ischemia; Caffeine; Humans; Randomized Controlled Trials as Topic; Stroke; Theo

2004
Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke.
    The Cochrane database of systematic reviews, 2000, Issue:2

    Topics: Aminophylline; Brain Ischemia; Caffeine; Humans; Stroke; Theophylline; Vasodilator Agents

2000

Trials

2 trials available for theophylline and Stroke

ArticleYear
Perfusion Changes in Acute Stroke Treated with Theophylline as an Add-on to Thrombolysis : A Randomized Clinical Trial Subgroup Analysis.
    Clinical neuroradiology, 2022, Volume: 32, Issue:2

    Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Humans; Infarction; Magnetic Resonance Imaging

2022
The neurophysiological effects of single-dose theophylline in patients with chronic stroke: A double-blind, placebo-controlled, randomized cross-over study.
    Restorative neurology and neuroscience, 2016, 09-21, Volume: 34, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Chronic Disease; Cross-Over Studies; Double-Blind Me

2016

Other Studies

9 other studies available for theophylline and Stroke

ArticleYear
Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial.
    Stroke, 2020, Volume: 51, Issue:7

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Female; Fibrinolytic Agents; Humans; Ischemia; Male; Middle

2020
[Effect of combined theophylline-ethylenediamine, rutin and ascorbic acid in therapy of cerebral apoplexy; early clinico-therapeutic results].
    Minerva medica, 1955, Jun-09, Volume: 46, Issue:46

    Topics: Aminophylline; Ascorbic Acid; Cerebral Hemorrhage; Ethylenediamines; Flavonoids; Humans; Rutin; Stro

1955
[Experience in the treatment of cerebral apoplexy].
    Medizinische Klinik, 1956, Feb-24, Volume: 51, Issue:8

    Topics: Cerebral Hemorrhage; Humans; Stroke; Theophylline

1956
[Treatment of stroke with peripherin-Homburg].
    Munchener medizinische Wochenschrift (1950), 1957, Nov-29, Volume: 99, Issue:48

    Topics: Cerebral Hemorrhage; Humans; Intermediate Filaments; Peripherins; Stroke; Theophylline

1957
[Treatment of apoplexy with a theophylline derivative & ephedrine in the light of recent pathogenetic theories].
    Polski tygodnik lekarski, 1959, May-04, Volume: 14, Issue:18

    Topics: Cerebral Hemorrhage; Ephedrine; Humans; Light; Stroke; Theophylline

1959
[On the therapy of apoplexy].
    Wiener medizinische Wochenschrift (1946), 1960, Oct-15, Volume: 110

    Topics: Aesculus; Cerebral Hemorrhage; Stroke; Theophylline

1960
[Clinical studies on the therapy of apoplexy].
    Die Medizinische Welt, 1960, May-14, Volume: 20

    Topics: Aesculus; Biomedical Research; Fagaceae; Stroke; Theophylline

1960
[ON THE TREATMENT OF APOPLEXY WITH COMPLAMIN (7-(2-HYDROXY-3-(N-2-HYDROXYETHYL-N-METHYLAMINO)PROPYL)THEOPHYLLINE NICOTINATE].
    Die Medizinische Welt, 1963, Oct-12, Volume: 41

    Topics: Cerebrovascular Disorders; Geriatrics; Humans; Niacin; Nicotinic Acids; Stroke; Theophylline; Xanthi

1963
[On the treatment of "apoplectic attacks" with apoplectal].
    Munchener medizinische Wochenschrift (1950), 1960, Jun-10, Volume: 102

    Topics: Aesculus; Fagaceae; Seizures; Stroke; Theophylline

1960