Page last updated: 2024-10-22

theophylline and Sleep Apnea Syndromes

theophylline has been researched along with Sleep Apnea Syndromes in 64 studies

Sleep Apnea Syndromes: Disorders characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep. Sleep apnea syndromes are divided into central (see SLEEP APNEA, CENTRAL), obstructive (see SLEEP APNEA, OBSTRUCTIVE), and mixed central-obstructive types.

Research Excerpts

ExcerptRelevanceReference
"In patients with stable heart failure, oral theophylline therapy reduced the number of episodes of apnea and hypopnea and the duration of arterial oxyhemoglobin desaturation during sleep."9.08Effect of theophylline on sleep-disordered breathing in heart failure. ( Javaheri, S; Liming, JD; Lindower, P; Parker, TJ; Roselle, GA; Wexler, L, 1996)
"To determine the prevalence of sleep-disordered breathing in patients with stable, optimally treated chronic congestive heart failure and the effect of short-term oral theophylline therapy on periodic breathing in these patients."7.72The effect of theophylline on sleep-disordered breathing in patients with stable chronic congestive heart failure. ( Chen, X; Hu, K; Hu, S; Li, Q; Yang, J, 2003)
"In an effort to characterize significant neonatal apnea and evaluate the nursing diagnosis of apnea, apnea type and frequency were determined in 27 infants by continuous computer recording of heart rate, respiratory impedance, end-tidal CO2, and either or both transcutaneous oxygen and pulse oximetry."7.67Neonatal apnea: diagnosis by nurse versus computer. ( Finer, NN; Muttitt, SC; Rossmann, J; Tierney, AJ, 1988)
" If no cause is found, the diagnosis of idiopathic infantile apnea is made."7.67Infantile apnea. ( McCulloch, K; Vidyasagar, D, 1986)
" The periodic breathing and apnea seemed to be caused by a decreased oxygen tension which can induce an instability of the central respiratory control mechanisms."7.66Ventilatory studies in two older infants with prolonged apnea. ( Broberger, U; Lagercrantz, H; Milerad, J; von Euler, C, 1980)
"Twenty-two full-term infants, aged 0 to 6 weeks, with a history of unexplained apnea and respiratory abnormalities on pneumogram recordings, were treated with theophylline (average dose 7."7.66Treatment of apnea and excessive periodic breathing in the full-term infant. ( Kelly, DH; Shannon, DC, 1981)
"Theophylline has a short-term relevant beneficial effect only on patients with mild OSA."5.30[Drug therapy of sleep apnea syndromes: results of short-term treatment with theophylline]. ( Di Martino, E; Emmerling, O; Saadi, R; Werner, E, 1999)
"In patients with stable heart failure, oral theophylline therapy reduced the number of episodes of apnea and hypopnea and the duration of arterial oxyhemoglobin desaturation during sleep."5.08Effect of theophylline on sleep-disordered breathing in heart failure. ( Javaheri, S; Liming, JD; Lindower, P; Parker, TJ; Roselle, GA; Wexler, L, 1996)
" Although more controlled studies would be helpful, relatively clear-cut indications for the use of ventilatory stimulants exist for hypercapnic obesity-hypoventilation patients (medroxyprogesterone), myxedema (thyroid replacement), central apnea (acetazolamide), and periodic breathing in congestive heart failure (theophylline)."4.80Pharmacologic treatment of sleep-disordered breathing. ( Hudgel, DW; Thanakitcharu, S, 1998)
"To determine the prevalence of sleep-disordered breathing in patients with stable, optimally treated chronic congestive heart failure and the effect of short-term oral theophylline therapy on periodic breathing in these patients."3.72The effect of theophylline on sleep-disordered breathing in patients with stable chronic congestive heart failure. ( Chen, X; Hu, K; Hu, S; Li, Q; Yang, J, 2003)
"The treatment of neonatal apnea and bradycardia with methylated xanthines--theophylline and caffeine--is generally accepted."3.68[Effect of methylxanthines on periodic respiration and acid gastroesophageal reflux in newborn infants]. ( Heimann, G; Koch, G; Skopnik, H, 1990)
"In an effort to characterize significant neonatal apnea and evaluate the nursing diagnosis of apnea, apnea type and frequency were determined in 27 infants by continuous computer recording of heart rate, respiratory impedance, end-tidal CO2, and either or both transcutaneous oxygen and pulse oximetry."3.67Neonatal apnea: diagnosis by nurse versus computer. ( Finer, NN; Muttitt, SC; Rossmann, J; Tierney, AJ, 1988)
" If no cause is found, the diagnosis of idiopathic infantile apnea is made."3.67Infantile apnea. ( McCulloch, K; Vidyasagar, D, 1986)
" The periodic breathing and apnea seemed to be caused by a decreased oxygen tension which can induce an instability of the central respiratory control mechanisms."3.66Ventilatory studies in two older infants with prolonged apnea. ( Broberger, U; Lagercrantz, H; Milerad, J; von Euler, C, 1980)
"Twenty-two full-term infants, aged 0 to 6 weeks, with a history of unexplained apnea and respiratory abnormalities on pneumogram recordings, were treated with theophylline (average dose 7."3.66Treatment of apnea and excessive periodic breathing in the full-term infant. ( Kelly, DH; Shannon, DC, 1981)
"In mild obstructive sleep apnea/hypopnea syndrome (OSAHS), night-to-night variability of parameters of sleep-disordered breathing has been determined rarely, we therefore compared the results of serial measurements of sleep apnea/hypopnea parameters under the effects of placebo and theophylline."2.69The therapeutic effect of theophylline in mild obstructive sleep Apnea/Hypopnea syndrome: results of repeated measurements with portable recording devices at home. ( Behnke, G; Hein, H; Jörres, RA; Magnussen, H, 2000)
"In patients with sleep apnea-syndrome nasal CPAP-therapy is the method of choice."2.67[Comparative studies on the effect of nasal CPAP, theophylline and oxygen in patients with sleep apnea syndrome]. ( Kempf, P; Kirchheiner, T; Mössinger, B; Müller, B; Rühle, KH, 1991)
"Acetazolamide have been established as the best medication."2.41[Drug therapy for sleep apnea syndrome]. ( Shimizu, T; Takahashi, Y, 2000)
"Obstructive sleep apnea is a prevalent disorder associated with significant neurobehavioral and cardiovascular morbidities."2.41Pharmacotherapies for obstructive sleep apnea: how close are we? ( Veasey, SC, 2001)
"He was subsequently diagnosed with sleep apnea associated with frequent and significant sinus pauses."1.42Sleep apnea and severe bradyarrhythmia--an alternative treatment option: a case report. ( Ahmed, W; Al-Faifi, SM; Alsheikh-Ali, AA; Asrar, F; Daoulah, A; Lotfi, A; Ocheltree, S, 2015)
"Theophylline has a short-term relevant beneficial effect only on patients with mild OSA."1.30[Drug therapy of sleep apnea syndromes: results of short-term treatment with theophylline]. ( Di Martino, E; Emmerling, O; Saadi, R; Werner, E, 1999)
"The lack of p-SPT effect on sleep apneas argues against a physiologic role for endogenous adenosine in the peripheral nervous system as a modulator of sleep apnea expression under baseline conditions."1.30Role of peripheral adenosine A(1) receptors in the regulation of sleep apneas in rats. ( Carley, DW; Radulovacki, M, 1999)
"In 1,150 patients with sleep apnea syndrome, the apnea number, the morning theophyllin level, the symptom of morning exhaustion were recorded for the first night of theophyllin therapy and in the follow-up period of up to 5 years; in addition, side effects were noted at the end of the observation period."1.29[Theophylline acceptance in long-term therapy of patients with obstructive sleep related respiratory disorder]. ( Dorow, P; Heinemann, S; Meissner, P; Thalhofer, S, 1995)
" Using an individual theophylline dosage with morning theophylline concentrations between 5 and 8 micrograms/ml, only few side effects occurred."1.29[Long-term treatment of sleep apnea with evening administration of oral retard theophylline]. ( Dorow, P; Heinemann, S; Kühler, U; Meissner, P; Thalhofer, S, 1993)
"There is a need to modify dosage schedule for these babies."1.29Kinetics of theophylline in apnea of prematurity in small for gestational age babies. ( Bhakoo, ON; Chaudhuri, M; Garg, SK; Narang, A, 1996)
" Using an individual theophylline dosage with morning theophylline concentration between 5 and 8 micrograms/ml, only few side-effects occurred."1.28[Long-term follow-up of sleep apnea therapy with sustained-release theophylline administered every evening]. ( Dorow, P; Kaufmann, U; Thalhofer, S, 1991)
"The pharmacokinetic profile of caffeine was studied in 15 premature infants."1.28Pharmacokinetic aspects of caffeine in premature infants. ( Carnevale, A; Chiarotti, M; De Carolis, MP; De Giovanni, N; Muzii, U; Romagnoli, C; Tortorolo, G, 1991)
"45) between the oral dosage given and the plasma concentrations found."1.28[Relation between dose, plasma concentration and therapeutic effect of theophylline in children with sleep apnea]. ( Calderón-Mandujano, B; Juárez-Olguín, H; Palma-Aguirre, JA; Rodríguez-Palomares, C; Ugartechea, JC, 1989)
"The caffeine half-life was 52."1.28Caffeine pharmacokinetics in preterm infants older than 2 weeks. ( Berlin, CM; Duran, C; Maisels, MJ; Pearlman, SA; Wood, MA, 1989)
"There were no deaths from SIDS."1.27Theophylline improves pneumogram abnormalities in infants at risk for sudden infant death syndrome. ( Brouillette, RT; Hanson, D; Hunt, CE, 1983)
"Etiologies to be considered include infections, metabolic aberrations, seizure problems, cardiac arrhythmias or congenital heart disease, anatomic airway abnormalities, gastroesophageal reflux and impaired regulation of breathing."1.27Evaluation and management of infantile apnea. ( Ariagno, RL, 1984)
"Two infants were siblings of a sudden infant death syndrome victim and one was a sibling of a "near miss" infant."1.26Episodic complete airway obstruction in infants. ( Kelly, DH; Shannon, DC, 1981)

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-199021 (32.81)18.7374
1990's31 (48.44)18.2507
2000's11 (17.19)29.6817
2010's1 (1.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Daoulah, A1
Ocheltree, S1
Al-Faifi, SM1
Ahmed, W1
Alsheikh-Ali, AA1
Asrar, F1
Lotfi, A1
Kimura, H1
Fukuoka, A1
Hu, K1
Li, Q1
Yang, J1
Hu, S1
Chen, X1
Fischer, R1
Lang, SM1
Leitl, M1
Thiere, M1
Steiner, U1
Huber, RM1
Vesalainen, R1
Gilmartin, GS1
Daly, RW1
Thomas, RJ1
Hunt, CE1
Brouillette, RT1
Hanson, D1
Ariagno, RL1
Lagercrantz, H1
Broberger, U1
Milerad, J2
von Euler, C1
Korner, AF1
Ruppel, EM1
Rho, JM1
Kelly, DH2
Shannon, DC2
Meissner, P2
Dorow, P7
Thalhofer, S6
Heinemann, S2
Schäfer, HH2
Peter, JH6
Fietze, I1
Warmuth, R1
Quispe-Bravo, S1
Waschke, K1
Grieger, E2
Heitmann, J1
Koehler, U1
Ploch, T2
Weber, K1
Hein, H2
Kirsten, D1
Jugert, C1
Magnussen, H2
Kühler, U1
Cassel, W1
Faust, M1
Penzel, T1
Schulze, B1
Schneider, H1
Weichler, U1
von Wichert, P2
Voigt, K1
Jaspersen, D1
Javaheri, S2
Parker, TJ1
Wexler, L1
Liming, JD1
Lindower, P1
Roselle, GA1
Chaudhuri, M1
Garg, SK1
Narang, A1
Bhakoo, ON1
Thornton, WK1
Roberts, DH1
Goggins, M1
Hudgel, DW1
Thanakitcharu, S1
Saletu, B2
Oberndorfer, S2
Anderer, P2
Gruber, G2
Divos, H1
Lachner, A1
Mandl, M2
Parapatics, S1
Popp, W1
Saletu, M2
Saletu-Zyhlarz, G2
Sertl, K1
Strobl, R1
Tschida, U1
Winkler, A1
Di Martino, E1
Saadi, R1
Emmerling, O1
Werner, E1
Carley, DW1
Radulovacki, M1
Glérant, JC1
Launois, SH1
Jounieaux, V1
Takahashi, Y1
Shimizu, T1
Behnke, G1
Jörres, RA1
Scholle, S1
Erler, T1
Wischniewski, E1
Veasey, SC1
Finer, NN2
Barrington, KJ1
Hayes, BJ1
Hugh, A1
Wiemann, J1
Sanner, B1
Sturm, A1
Martin, RJ1
Mulloy, E1
McNicholas, WT1
Kaufmann, U3
Schörder, J1
Kempf, P1
Mössinger, B1
Müller, B1
Kirchheiner, T1
Rühle, KH2
De Carolis, MP1
Romagnoli, C1
Muzii, U1
Tortorolo, G1
Chiarotti, M1
De Giovanni, N1
Carnevale, A1
Becker, H1
Blanke, J1
Clarenbach, P1
Mayer, G1
Raschke, F1
Rüther, E1
Schläfke, M1
Schönbrunn, E1
Skopnik, H1
Koch, G1
Heimann, G1
Harrison, VC1
Peat, GM1
Rodríguez-Palomares, C1
Ugartechea, JC1
Palma-Aguirre, JA1
Juárez-Olguín, H1
Calderón-Mandujano, B1
Schnabel, D1
Sybrecht, GW1
Pearlman, SA1
Duran, C1
Wood, MA1
Maisels, MJ1
Berlin, CM1
Colp, C1
Schneider, R1
Altarac, D1
Kuriyama, T1
Tojima, H1
Lombard, RM1
Zwillich, CW1
Muttitt, SC1
Tierney, AJ1
Rossmann, J1
Amend, G1
Stephan, S1
Jung, W1
Ockenga, A1
Himmelmann, H1
Steinijans, VW1
Sweeney, LB1
McCulloch, K1
Vidyasagar, D1
Waldhorn, RE1
Thoman, EB1
Davis, DH1
Raye, JR1
Philipps, AF1
Rowe, JC1
Denenberg, VH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of High-altitude Sleep Disturbance: A Double-blind Comparison of Temazepam Versus Acetazolamide.[NCT01519544]34 participants (Actual)Interventional2012-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

15 reviews available for theophylline and Sleep Apnea Syndromes

ArticleYear
Recognition and management of complex sleep-disordered breathing.
    Current opinion in pulmonary medicine, 2005, Volume: 11, Issue:6

    Topics: Acetazolamide; Airway Resistance; Carbon Dioxide; Humans; Hypocapnia; Oxygen Inhalation Therapy; Pol

2005
Theophylline therapy in sleep apnoea syndrome.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 1993, Volume: 48, Issue:6

    Topics: Humans; Sleep Apnea Syndromes; Theophylline

1993
[Reflux associated respiratory tract diseases].
    Deutsche medizinische Wochenschrift (1946), 1996, Apr-05, Volume: 121, Issue:14

    Topics: Bronchiectasis; Bronchitis; Bronchodilator Agents; Chronic Disease; Esophagogastric Junction; Gastro

1996
Nonsurgical management of the obstructive sleep apnea patient.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1996, Volume: 54, Issue:9

    Topics: Antidepressive Agents, Tricyclic; Bronchodilator Agents; Humans; Occlusal Splints; Positive-Pressure

1996
Pharmacologic treatment of sleep-disordered breathing.
    American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:3

    Topics: Acetazolamide; Antihypertensive Agents; Apnea; Bronchodilator Agents; Diuretics; Dyspnea; Evidence-B

1998
[Intensive care and respiratory sleep disorders].
    Revue des maladies respiratoires, 1999, Volume: 16, Issue:6

    Topics: Acute Disease; Aged; Almitrine; Anti-Inflammatory Agents; Bronchodilator Agents; Critical Care; Diur

1999
[Drug therapy for sleep apnea syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 2000, Volume: 58, Issue:8

    Topics: Acetazolamide; Aminophylline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbonic Anhydrase

2000
[Theophylline in the treatment of sleep-related breathing disorders].
    Zeitschrift fur arztliche Fortbildung und Qualitatssicherung, 2001, Volume: 95, Issue:1

    Topics: Adult; Bronchodilator Agents; Cheyne-Stokes Respiration; Heart Failure; Humans; Infant; Sleep Apnea

2001
Pharmacotherapies for obstructive sleep apnea: how close are we?
    Current opinion in pulmonary medicine, 2001, Volume: 7, Issue:6

    Topics: Animals; Bronchodilator Agents; Disease Models, Animal; Humans; Receptors, Serotonin; Serotonin Anta

2001
[Sleep apnea. Pathophysiology, diagnosis, therapy].
    Zeitschrift fur arztliche Fortbildung, 1992, Dec-22, Volume: 86, Issue:23-24

    Topics: Carbon Dioxide; Follow-Up Studies; Humans; Oxygen; Polysomnography; Signal Processing, Computer-Assi

1992
[Sleep apnea syndrome].
    Deutsche medizinische Wochenschrift (1946), 1992, Dec-11, Volume: 117, Issue:50

    Topics: Diagnosis, Differential; Electrocardiography; Female; Heart Diseases; Humans; Male; Middle Aged; Obe

1992
Nocturnal asthma.
    Clinics in chest medicine, 1992, Volume: 13, Issue:3

    Topics: Adrenal Cortex Hormones; Asthma; Bronchial Hyperreactivity; Circadian Rhythm; Gastroesophageal Reflu

1992
[Drug therapy of sleep-related respiration disorders].
    Pneumologie (Stuttgart, Germany), 1991, Volume: 45 Suppl 1

    Topics: Carbonic Anhydrase Inhibitors; Humans; Medroxyprogesterone; Protriptyline; Sleep Apnea Syndromes; Th

1991
[Recommendations for diagnosis, therapy and long-term management of patients with sleep apnea].
    Medizinische Klinik (Munich, Germany : 1983), 1991, Jan-15, Volume: 86, Issue:1

    Topics: Combined Modality Therapy; Diagnosis, Differential; Humans; Respiration, Artificial; Sleep Apnea Syn

1991
Medical therapy of obstructive sleep apnea.
    The Medical clinics of North America, 1985, Volume: 69, Issue:6

    Topics: Almitrine; Central Nervous System Stimulants; Diet, Reducing; Humans; Intubation; Male; Naloxone; Na

1985

Trials

12 trials available for theophylline and Sleep Apnea Syndromes

ArticleYear
Theophylline and acetazolamide reduce sleep-disordered breathing at high altitude.
    The European respiratory journal, 2004, Volume: 23, Issue:1

    Topics: Acetazolamide; Administration, Oral; Altitude; Altitude Sickness; Apnea; Autacoids; Blood Gas Analys

2004
Effect of theophylline on sleep-disordered breathing in heart failure.
    The New England journal of medicine, 1996, Aug-22, Volume: 335, Issue:8

    Topics: Cardiac Output; Cross-Over Studies; Double-Blind Method; Heart Failure; Humans; Male; Oxygen; Respir

1996
Efficiency of continuous positive airway pressure versus theophylline therapy in sleep apnea: comparative sleep laboratory studies on objective and subjective sleep and awakening quality.
    Neuropsychobiology, 1999, Volume: 39, Issue:3

    Topics: Bronchodilator Agents; Cross-Over Studies; Humans; Male; Middle Aged; Polysomnography; Positive-Pres

1999
Theophylline in snoring and sleep-related breathing disorders: sleep laboratory investigations on subjective and objective sleep and awakening quality.
    Methods and findings in experimental and clinical pharmacology, 2000, Volume: 22, Issue:4

    Topics: Adult; Aged; Cross-Over Studies; Female; Humans; Male; Middle Aged; Single-Blind Method; Sleep; Slee

2000
The therapeutic effect of theophylline in mild obstructive sleep Apnea/Hypopnea syndrome: results of repeated measurements with portable recording devices at home.
    European journal of medical research, 2000, Sep-18, Volume: 5, Issue:9

    Topics: Adult; Bronchodilator Agents; Double-Blind Method; Equipment and Supplies; Female; Humans; Male; Mid

2000
Obstructive, mixed, and central apnea in the neonate: physiologic correlates.
    The Journal of pediatrics, 1992, Volume: 121, Issue:6

    Topics: Analysis of Variance; Doxapram; Drug Therapy, Combination; Heart Rate; Humans; Infant, Newborn; Infa

1992
Theophylline in obstructive sleep apnea. A double-blind evaluation.
    Chest, 1992, Volume: 101, Issue:3

    Topics: Adult; Double-Blind Method; Humans; Male; Middle Aged; Oxygen; Respiration; Sleep Apnea Syndromes; S

1992
[Comparative studies on the effect of nasal CPAP, theophylline and oxygen in patients with sleep apnea syndrome].
    Pneumologie (Stuttgart, Germany), 1991, Volume: 45 Suppl 1

    Topics: Humans; Middle Aged; Oxygen; Oxygen Inhalation Therapy; Positive-Pressure Respiration; Sleep Apnea S

1991
[Treatment of nocturnal bronchial asthma].
    Pneumologie (Stuttgart, Germany), 1989, Volume: 43 Suppl 1

    Topics: Adolescent; Adult; Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Metho

1989
[Therapy of sleep apnea with an evening dose of retard theophylline (Euphylong)].
    Praxis und Klinik der Pneumologie, 1987, Volume: 41, Issue:10

    Topics: Clinical Trials as Topic; Delayed-Action Preparations; Drug Administration Schedule; Humans; Male; M

1987
[Therapy of nocturnal bronchial asthma: comparison of various doses of retard theophylline].
    Praxis und Klinik der Pneumologie, 1987, Volume: 41, Issue:10

    Topics: Adult; Aged; Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationsh

1987
Theophylline affects sleep-wake state development in premature infants.
    Neuropediatrics, 1985, Volume: 16, Issue:1

    Topics: Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Sleep Apnea Syndromes; Theophyll

1985

Other Studies

37 other studies available for theophylline and Sleep Apnea Syndromes

ArticleYear
Sleep apnea and severe bradyarrhythmia--an alternative treatment option: a case report.
    Journal of medical case reports, 2015, May-15, Volume: 9

    Topics: Bradycardia; Humans; Male; Middle Aged; Obesity; Polysomnography; Sleep Apnea Syndromes; Theophyllin

2015
[Progress in the field of pulmonary medicine in the last 100 years: Sleep apnea syndrome].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2002, Jun-10, Volume: 91, Issue:6

    Topics: Acetazolamide; Antidepressive Agents, Tricyclic; Carbonic Anhydrase Inhibitors; Diaphragm; Electric

2002
The effect of theophylline on sleep-disordered breathing in patients with stable chronic congestive heart failure.
    Chinese medical journal, 2003, Volume: 116, Issue:11

    Topics: Aged; Chronic Disease; Female; Heart Failure; Humans; Male; Middle Aged; Sleep Apnea Syndromes; Theo

2003
[Uncontrolled hyperventilation].
    Duodecim; laaketieteellinen aikakauskirja, 2004, Volume: 120, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Depressive Disorder; Drug Therapy, Combination; Finland; Follow-U

2004
Theophylline improves pneumogram abnormalities in infants at risk for sudden infant death syndrome.
    The Journal of pediatrics, 1983, Volume: 103, Issue:6

    Topics: Cheyne-Stokes Respiration; Electrocardiography; Humans; Infant; Monitoring, Physiologic; Respiration

1983
Evaluation and management of infantile apnea.
    Pediatric annals, 1984, Volume: 13, Issue:3

    Topics: Humans; Infant; Monitoring, Physiologic; Sleep Apnea Syndromes; Sudden Infant Death; Theophylline

1984
Ventilatory studies in two older infants with prolonged apnea.
    Acta paediatrica Scandinavica, 1980, Volume: 69, Issue:4

    Topics: Apnea; Carbon Dioxide; Female; Heart Rate; Humans; Infant; Infant, Newborn; Infant, Newborn, Disease

1980
Effects of water beds on the sleep and motility of theophylline-treated preterm infants.
    Pediatrics, 1982, Volume: 70, Issue:6

    Topics: Beds; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Movement; Sleep; Sleep Apn

1982
Episodic complete airway obstruction in infants.
    Pediatrics, 1981, Volume: 67, Issue:6

    Topics: Airway Obstruction; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Infant, Newb

1981
Treatment of apnea and excessive periodic breathing in the full-term infant.
    Pediatrics, 1981, Volume: 68, Issue:2

    Topics: Apnea; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Sleep Apnea Syndrom

1981
[Theophylline acceptance in long-term therapy of patients with obstructive sleep related respiratory disorder].
    Pneumologie (Stuttgart, Germany), 1995, Volume: 49 Suppl 1

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Humans; Long-Term Care; Longitudinal Studies;

1995
[Therapeutic consequences of obstructive sleep apnea syndrome--results of drug, mechanical and surgical treatment].
    Pneumologie (Stuttgart, Germany), 1993, Volume: 47 Suppl 4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Behavior Therapy; Female; Follow-Up Studies; Humans; Mal

1993
[Long-term theophylline therapy in sleep apnea--follow-up over a period of 12 months].
    Pneumologie (Stuttgart, Germany), 1993, Volume: 47 Suppl 4

    Topics: Adult; Aged; Airway Resistance; Ambulatory Care; Drug Administration Schedule; Follow-Up Studies; Hu

1993
[Theophylline in therapy of obstructive sleep apnea?].
    Pneumologie (Stuttgart, Germany), 1993, Volume: 47 Suppl 4

    Topics: Adult; Aged; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; Long-Term Ca

1993
[Long-term treatment of sleep apnea with evening administration of oral retard theophylline].
    Pneumologie (Stuttgart, Germany), 1993, Volume: 47 Suppl 4

    Topics: Administration, Oral; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Stud

1993
[Sleep-related respiratory disorders: early detection and follow-up by close patient contact].
    Pneumologie (Stuttgart, Germany), 1993, Volume: 47 Suppl 1

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Combined Modality Therapy; Female; Follow-Up Studies; Hosp

1993
[Therapy control of theophylline evening dosage in patients with sleep-related respiratory disorders--follow-up study].
    Pneumologie (Stuttgart, Germany), 1993, Volume: 47 Suppl 1

    Topics: Adult; Aged; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Administration Schedule; Femal

1993
Kinetics of theophylline in apnea of prematurity in small for gestational age babies.
    Indian pediatrics, 1996, Volume: 33, Issue:3

    Topics: Aminophylline; Bronchodilator Agents; Case-Control Studies; Dose-Response Relationship, Drug; Drug A

1996
Theophylline and sleep-disordered breathing in heart failure.
    The New England journal of medicine, 1997, Jan-30, Volume: 336, Issue:5

    Topics: Arrhythmias, Cardiac; Heart Failure; Humans; Sleep Apnea Syndromes; Theophylline

1997
Central sleep apnea-hypopnea syndrome in heart failure: prevalence, impact, and treatment.
    Sleep, 1996, Volume: 19, Issue:10 Suppl

    Topics: Benzodiazepines; Cheyne-Stokes Respiration; Combined Modality Therapy; Functional Laterality; Heart

1996
[Drug therapy of sleep apnea syndromes: results of short-term treatment with theophylline].
    Laryngo- rhino- otologie, 1999, Volume: 78, Issue:3

    Topics: Administration, Oral; Adult; Age Factors; Aged; Body Mass Index; Delayed-Action Preparations; Female

1999
Role of peripheral adenosine A(1) receptors in the regulation of sleep apneas in rats.
    Experimental neurology, 1999, Volume: 159, Issue:2

    Topics: Adenosine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Male; Purinergic P1 Receptor A

1999
Sleep medicine in infants--practicability and limitations.
    Early human development, 2001, Volume: 63, Issue:1

    Topics: Bronchodilator Agents; Female; Gestational Age; Humans; Infant; Infant, Newborn; Longitudinal Studie

2001
[Therapy of sleep apnea with theophylline (Uniphylline) administration every evening].
    Pneumologie (Stuttgart, Germany), 1991, Volume: 45 Suppl 1

    Topics: Adult; Death, Sudden; Humans; Male; Middle Aged; Radioimmunoassay; Sleep Apnea Syndromes; Theophylli

1991
[Long-term follow-up of sleep apnea therapy with sustained-release theophylline administered every evening].
    Pneumologie (Stuttgart, Germany), 1991, Volume: 45 Suppl 1

    Topics: Adult; Delayed-Action Preparations; Drug Administration Schedule; Electrophysiology; Female; Humans;

1991
Pharmacokinetic aspects of caffeine in premature infants.
    Developmental pharmacology and therapeutics, 1991, Volume: 16, Issue:3

    Topics: Biotransformation; Caffeine; Humans; Infant, Newborn; Infant, Premature; Injections, Intravenous; Sl

1991
[Effect of methylxanthines on periodic respiration and acid gastroesophageal reflux in newborn infants].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1990, Volume: 138, Issue:3

    Topics: Bradycardia; Caffeine; Citrates; Drug Combinations; Drug Therapy, Combination; Gastric Acidity Deter

1990
Alpha-fetoprotein: a marker for recurrent apnoea of prematurity?
    Early human development, 1989, Volume: 20, Issue:3-4

    Topics: alpha-Fetoproteins; Biomarkers; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant, Premature

1989
[Relation between dose, plasma concentration and therapeutic effect of theophylline in children with sleep apnea].
    Boletin medico del Hospital Infantil de Mexico, 1989, Volume: 46, Issue:12

    Topics: Dose-Response Relationship, Drug; Female; Humans; Infant; Infant, Newborn; Male; Sleep Apnea Syndrom

1989
Caffeine pharmacokinetics in preterm infants older than 2 weeks.
    Developmental pharmacology and therapeutics, 1989, Volume: 12, Issue:2

    Topics: Caffeine; Chromatography, High Pressure Liquid; Half-Life; Humans; Infant; Infant, Newborn; Infant,

1989
Ondine's curse revisited.
    New York state journal of medicine, 1989, Volume: 89, Issue:4

    Topics: Aged; Humans; Male; Maximal Midexpiratory Flow Rate; Respiration; Respiratory Function Tests; Sleep

1989
[Drug therapy of respiratory disturbances during sleep].
    Kokyu to junkan. Respiration & circulation, 1989, Volume: 37, Issue:1

    Topics: Acetazolamide; Humans; Progesterone; Protriptyline; Sleep Apnea Syndromes; Theophylline

1989
Neonatal apnea: diagnosis by nurse versus computer.
    Pediatrics, 1988, Volume: 82, Issue:5

    Topics: Apnea; Computers; Heart Rate; Humans; Infant, Newborn; Monitoring, Physiologic; Nursing Assessment;

1988
Impact on families caring for an infant with apnea.
    Issues in comprehensive pediatric nursing, 1988, Volume: 11, Issue:1

    Topics: Adult; Chronic Disease; Family; Female; Humans; Infant; Monitoring, Physiologic; Mother-Child Relati

1988
Effects of theophylline on ventilatory response to hypoxic challenge.
    Archives of disease in childhood, 1987, Volume: 62, Issue:12

    Topics: Arousal; Female; Humans; Infant, Newborn; Male; Oxygen; Respiration; Sleep Apnea Syndromes; Theophyl

1987
Infantile apnea.
    American family physician, 1986, Volume: 34, Issue:3

    Topics: Apnea; Breast Feeding; Diagnosis, Differential; Gastroesophageal Reflux; Humans; Infant; Infant, New

1986
Sleep apnea syndrome.
    American family physician, 1985, Volume: 32, Issue:3

    Topics: Acetazolamide; Adult; Diagnosis, Differential; Electrocardiography; Electroencephalography; Electroo

1985