theophylline has been researched along with Pregnancy in 382 studies
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the effectiveness of 20:1 cafedrine/theodrenaline approved for use in Germany to ephedrine in the restoration of arterial blood pressure and on post-operative outcomes in patients with intra-operative arterial hypotension of any origin under standard clinical practice conditions." | 9.27 | A non-interventional comparative study of the 20:1 combination of cafedrine/theodrenaline versus ephedrine for the treatment of intra-operative arterial hypotension: the 'HYPOTENS' study design and rationale. ( Eberhart, L; Geldner, G; Huljic, S; Keller, T; Koch, T; Kranke, P; Marggraf, K, 2018) |
| "This study sought to assess the pharmacokinetic (PK) changes of caffeine and its CYP1A2 metabolites across the 3 trimesters of pregnancy." | 9.22 | Pregnancy-induced changes in the pharmacokinetics of caffeine and its metabolites. ( Campbell, SC; Clark, EA; Schoen, K; Sherwin, CM; Spigarelli, MG; Stockmann, C; Tak, C; Varner, MW; Yu, T, 2016) |
| "This study was undertaken to compare the efficacy of inhaled beclomethasone dipropionate to oral theophylline for the prevention of asthma exacerbation(s) requiring medical intervention." | 9.11 | Randomized trial of inhaled beclomethasone dipropionate versus theophylline for moderate asthma during pregnancy. ( Caritis, SN; Conway, DL; Dombrowski, MP; Hauth, JC; Landon, M; Leveno, KJ; Lindheimer, M; Mabie, W; McNellis, D; Meis, P; Miodovnik, M; Newman, RB; O'Sullivan, MJ; Schatz, M; Thom, EA; Varner, MW; Wapner, RJ; Wise, R, 2004) |
| "Mean plasma adenosine concentration in preeclampsia was significantly higher than that in normal pregnancy (0." | 9.10 | Relation between adenosine and T-helper 1/T-helper 2 imbalance in women with preeclampsia. ( Araki, T; Power, GG; Sawa, R; Suzuki, S; Yoneyama, K; Yoneyama, Y, 2002) |
| "In Germany, hypotension induced by spinal anaesthesia is commonly treated with a combination of cafedrine hydrochloride (C, 200 mg) and theodrenaline hydrochloride (T, 10 mg) in 2 ml." | 8.02 | Treatment of spinal anaesthesia-induced hypotension with cafedrine/theodrenaline versus ephedrine during caesarean section: Results from HYPOTENS, a national, multicentre, prospective, noninterventional study. ( Chappell, D; Eberhart, LHJ; Geldner, G; Gerbershagen, HJ; Huljic, S; Keller, T; Kienbaum, P; Koch, T; Kranke, P; Kunitz, O; Linstedt, U; Wallenborn, J; Weber, S, 2021) |
| "Although caffeine is commonly consumed during pregnancy, there are few reports on the association of in utero caffeine exposure with offspring cognition or behavior during childhood." | 7.81 | Maternal Caffeine Intake During Pregnancy and Child Cognition and Behavior at 4 and 7 Years of Age. ( Keim, SA; Klebanoff, MA, 2015) |
| "Outside pregnancy, acute caffeine consumption is associated with insulin resistance." | 7.77 | Caffeine and insulin resistance in pregnancy. ( Catov, J; Laughon, SK; Parana, S; Powers, RW; Roberts, JM, 2011) |
| " We have investigated how CHU affects cardiovascular responses evoked by acute systemic hypoxia in adult male offspring, recognising that adenosine contributes to hypoxia-induced muscle vasodilatation and bradycardia by acting on A(1) receptors in normal (N) rats." | 7.76 | Effects of maternal hypoxia on muscle vasodilatation evoked by acute systemic hypoxia in adult rat offspring: changed roles of adenosine and A1 receptors. ( Coney, AM; Marshall, JM, 2010) |
| "The aim of this work was to study whether caffeine or theophylline chronically consumed during pregnancy affect inhibitory adenylyl cyclase pathway mediated by adenosine, in rat brain of both mothers and full-term fetuses." | 7.73 | Chronic caffeine or theophylline intake during pregnancy inhibits A1 receptor function in the rat brain. ( Albasanz, JL; León, D; Martín, M; Ruíz, MA, 2005) |
| "Previous studies of maternal caffeine use and pregnancy outcome have relied on self-reported use." | 7.70 | Serum caffeine and paraxanthine as markers for reported caffeine intake in pregnancy. ( Clemens, JD; Dersimonian, R; Klebanoff, MA; Levine, RJ; Wilkins, DG, 1998) |
| "Oral theophylline treatment may be helpful in controlling severe asthma during pregnancy." | 7.69 | Slow-release theophylline in pregnant asthmatics. ( Riikonen, S; Stenius-Aarniala, B; Teramo, K, 1995) |
| "A single bolus dose of theophylline (Th; 5 mg/kg) was administered through the abdominal catheter in nonpregnant and pregnant rats to measure unbound fraction (fu) of Th in pregnancy." | 7.69 | Plasma protein binding of theophylline in late pregnancy in rat. ( Smeaton, TC; Sultana, S, 1997) |
| "A 32 year old pregnant woman who had taken large doses of theophylline for asthmatic attack was brought to our emergency medical center with convulsion and respiratory disturbance." | 7.68 | [Severe theophylline toxicity in a pregnant asthmatic patient]. ( Kasagawa, J; Nagahama, H; Nagano, K; Seki, I; Suzuki, Y; Yamanaka, I, 1993) |
| "The purpose of the investigation was to determine the effects of pregnancy on theophylline pharmacokinetics and to clarify the clinical effect of theophylline treatment in cases of threatened anoxemia of foetus." | 7.68 | [Pharmacokinetic examination of theophylline in pregnancy in cases of fetal anoxia]. ( Chmielewski, S; Jankowski, A; Skublicki, S; Szymański, M; Szymański, W, 1992) |
| "The effects of pregnancy on the disposition of theophylline were assessed in 10 patients throughout pregnancy and post-partum." | 7.67 | Longitudinal effects of pregnancy on the pharmacokinetics of theophylline. ( Cousins, L; Gardner, MJ; Jusko, WJ; Middleton, E; Schatz, M; Zeiger, R, 1987) |
| "The incidence of preeclampsia was reduced among asthmatic patients taking theophylline (one of 85) compared to other asthmatic patients (six of 68, p less than 0." | 7.67 | Incidence of preeclampsia among asthmatic patients lower with theophylline. ( Boike, GM; Bottoms, SF; Dombrowski, MP; Wald, J, 1986) |
| "Theophylline pharmacokinetics were studied serially in five women during and after pregnancy." | 7.67 | Theophylline pharmacokinetics in pregnancy. ( Atkinson, AJ; Chow, MJ; Frederiksen, MC; Ruo, TI, 1986) |
| "Theophylline clearance was prospectively studied in eight pregnant asthmatic patients who were receiving maintenance doses of theophylline." | 7.67 | Theophylline clearance during pregnancy. ( Carter, BL; Driscoll, CE; Smith, GD, 1986) |
| "After literature reports linking fibrocystic breast disease (FBD) to methylxanthine ingestion, a pilot study was undertaken to investigate the possible contribution of theophylline to this effect." | 7.67 | Theophylline and fibrocystic breast disease. ( Bullough, B; Hindi-Alexander, MC; London, WM; Middleton, E; Montes, N; Rosner, DH; Zielezny, MA, 1985) |
| "The newborn's potential for xanthine toxic reactions from placental transfer of theophylline or caffeine conversion from theophylline was studied in 12 newborns of asthmatic mothers." | 7.66 | Placental theophylline transfer in pregnant asthmatics. ( Labovitz, E; Spector, S, 1982) |
| "Terbutaline is used for the management of bronchospasm associated with asthma, bronchitis, emphysema, and chronic obstructive pulmonary disease." | 5.41 | Clinical pharmacokinetics of terbutaline in humans: a systematic review. ( Ashraf, W; Imran, I; Majeed, A; Rasool, MF; Rehman, AU; Saeed, H; Sultan, K; Zamir, A, 2023) |
| "Adenosine is an established platelet activation suppressor." | 5.31 | Plasma adenosine levels and P-selectin expression on platelets in preeclampsia. ( Araki, T; Kiyokawa, Y; Power, GG; Sawa, R; Suzuki, S; Yoneyama, Y, 2001) |
| "To compare the effectiveness of 20:1 cafedrine/theodrenaline approved for use in Germany to ephedrine in the restoration of arterial blood pressure and on post-operative outcomes in patients with intra-operative arterial hypotension of any origin under standard clinical practice conditions." | 5.27 | A non-interventional comparative study of the 20:1 combination of cafedrine/theodrenaline versus ephedrine for the treatment of intra-operative arterial hypotension: the 'HYPOTENS' study design and rationale. ( Eberhart, L; Geldner, G; Huljic, S; Keller, T; Koch, T; Kranke, P; Marggraf, K, 2018) |
| "This study sought to assess the pharmacokinetic (PK) changes of caffeine and its CYP1A2 metabolites across the 3 trimesters of pregnancy." | 5.22 | Pregnancy-induced changes in the pharmacokinetics of caffeine and its metabolites. ( Campbell, SC; Clark, EA; Schoen, K; Sherwin, CM; Spigarelli, MG; Stockmann, C; Tak, C; Varner, MW; Yu, T, 2016) |
| "We used a secondary observational analysis of pregnant women with mild and moderate-severe asthma enrolled in a prospective observational cohort study of asthma in pregnancy and a randomized clinical trial (RCT) comparing inhaled beclomethasone and oral theophylline." | 5.14 | The effect of active and passive household cigarette smoke exposure on pregnant women with asthma. ( Caritis, SN; Conway, DL; Dombrowski, MP; Landon, M; Lindheimer, M; Miodovnik, M; Momirova, V; Newman, RB; O'Sullivan, MJ; Rouse, DJ; Schatz, M; Sheffield, J; Varner, MW; Wapner, RJ; Wise, R, 2010) |
| "This study was undertaken to compare the efficacy of inhaled beclomethasone dipropionate to oral theophylline for the prevention of asthma exacerbation(s) requiring medical intervention." | 5.11 | Randomized trial of inhaled beclomethasone dipropionate versus theophylline for moderate asthma during pregnancy. ( Caritis, SN; Conway, DL; Dombrowski, MP; Hauth, JC; Landon, M; Leveno, KJ; Lindheimer, M; Mabie, W; McNellis, D; Meis, P; Miodovnik, M; Newman, RB; O'Sullivan, MJ; Schatz, M; Thom, EA; Varner, MW; Wapner, RJ; Wise, R, 2004) |
| "Mean plasma adenosine concentration in preeclampsia was significantly higher than that in normal pregnancy (0." | 5.10 | Relation between adenosine and T-helper 1/T-helper 2 imbalance in women with preeclampsia. ( Araki, T; Power, GG; Sawa, R; Suzuki, S; Yoneyama, K; Yoneyama, Y, 2002) |
| "inhaled magnesium sulphate in acute asthma was shown to improve lung function measures (one trial, 60 women); intravenous theophylline in acute asthma was not associated with benefits (one trial, 65 women)." | 4.90 | Interventions for managing asthma in pregnancy. ( Bain, E; Clifton, VL; Crowther, CA; Hodyl, NA; Middleton, P; Pierides, KL; Stark, MJ, 2014) |
| "We examined preconception and pregnancy caffeine exposure with DNAm alterations in neonate cord blood (n = 378)." | 4.12 | Maternal caffeine intake and DNA methylation in newborn cord blood. ( Guan, W; Mumford, SL; Polinski, KJ; Purdue-Smithe, A; Robinson, SL; Schisterman, EF; Schliep, KC; Silver, RM; Yeung, EH; Zhao, SK, 2022) |
| "In Germany, hypotension induced by spinal anaesthesia is commonly treated with a combination of cafedrine hydrochloride (C, 200 mg) and theodrenaline hydrochloride (T, 10 mg) in 2 ml." | 4.02 | Treatment of spinal anaesthesia-induced hypotension with cafedrine/theodrenaline versus ephedrine during caesarean section: Results from HYPOTENS, a national, multicentre, prospective, noninterventional study. ( Chappell, D; Eberhart, LHJ; Geldner, G; Gerbershagen, HJ; Huljic, S; Keller, T; Kienbaum, P; Koch, T; Kranke, P; Kunitz, O; Linstedt, U; Wallenborn, J; Weber, S, 2021) |
| "Higher caffeine consumption during pregnancy has been associated with lower birth weight." | 4.02 | Association Between Maternal Caffeine Consumption and Metabolism and Neonatal Anthropometry: A Secondary Analysis of the NICHD Fetal Growth Studies-Singletons. ( Amyx, M; Bever, AM; Buck Louis, GM; Gerlanc, N; Gleason, JL; Grantz, KL; Hinkle, SN; Kannan, K; Robinson, M; Smarr, MM; Sundaram, R; Tekola-Ayele, F; Vafai, Y, 2021) |
| "This study does not support an increased risk of childhood obesity with increasing maternal caffeine consumption during pregnancy." | 3.81 | Maternal serum paraxanthine during pregnancy and offspring body mass index at ages 4 and 7 years. ( Keim, SA; Klebanoff, MA, 2015) |
| "Although caffeine is commonly consumed during pregnancy, there are few reports on the association of in utero caffeine exposure with offspring cognition or behavior during childhood." | 3.81 | Maternal Caffeine Intake During Pregnancy and Child Cognition and Behavior at 4 and 7 Years of Age. ( Keim, SA; Klebanoff, MA, 2015) |
| " Human myometrial strips from cesarean sections at full-term pregnancy and at preterm labor were stimulated with oxytocin, and the inhibitory effects of theophylline, rolipram and terbutaline were studied." | 3.79 | Uterus-relaxing effect of β2-agonists in combination with phosphodiesterase inhibitors: studies on pregnant rat in vivo and on pregnant human myometrium in vitro. ( Ducza, E; Falkay, G; Gáspár, R; Hajagos-Tóth, J; Klukovits, A; Kormányos, Z; Seres, AB; Verli, J, 2013) |
| "Outside pregnancy, acute caffeine consumption is associated with insulin resistance." | 3.77 | Caffeine and insulin resistance in pregnancy. ( Catov, J; Laughon, SK; Parana, S; Powers, RW; Roberts, JM, 2011) |
| " We have investigated how CHU affects cardiovascular responses evoked by acute systemic hypoxia in adult male offspring, recognising that adenosine contributes to hypoxia-induced muscle vasodilatation and bradycardia by acting on A(1) receptors in normal (N) rats." | 3.76 | Effects of maternal hypoxia on muscle vasodilatation evoked by acute systemic hypoxia in adult rat offspring: changed roles of adenosine and A1 receptors. ( Coney, AM; Marshall, JM, 2010) |
| " Our aim was to study the effects of the non-selective phosphodiesterase (PDE) inhibitor theophylline and the selective PDE4 inhibitor rolipram on the uteri of intact late-pregnant female rats (on days 20 and 22 of pregnancy) and of pregnant rats treated with lipopolysaccharide (LPS) to evoke preterm labor (on day 20)." | 3.76 | Improving the relaxing effect of terbutaline with phosphodiesterase inhibitors: studies on pregnant rat uteri in vitro. ( Falkay, G; Gáspár, R; Klukovits, A; Verli, J, 2010) |
| "The aim of this work was to study whether caffeine or theophylline chronically consumed during pregnancy affect inhibitory adenylyl cyclase pathway mediated by adenosine, in rat brain of both mothers and full-term fetuses." | 3.73 | Chronic caffeine or theophylline intake during pregnancy inhibits A1 receptor function in the rat brain. ( Albasanz, JL; León, D; Martín, M; Ruíz, MA, 2005) |
| "Preterm delivery was not associated with asthma diagnosis, severity, or symptoms but was associated with use of controller medications, independent of symptoms, specifically oral steroids and theophylline." | 3.72 | Asthma symptoms, severity, and drug therapy: a prospective study of effects on 2205 pregnancies. ( Beckett, WS; Belanger, K; Bracken, MB; Leaderer, BP; Saftlas, A; Triche, EW, 2003) |
| "Pregnant rats were treated daily with 1 g/L of caffeine or theophylline in their drinking water during pregnancy and the effect of these methylxanthines on adenosine A1 receptor was assayed using binding and reverse transcription polymerase chain reaction (RT-PCR) assays in brains from both mothers and full-term fetuses." | 3.71 | Adenosine A1 receptor down-regulation in mothers and fetal brain after caffeine and theophylline treatments to pregnant rats. ( Albasanz, JL; Fernández, M; León, D; Martín, M; Ruíz, MA, 2002) |
| " 1990) established that caffeine, when administered during pregnancy, significantly inhibited the differentiation of the seminiferous cords and subsequent Leydig cell development in the interstitium." | 3.71 | Effects of caffeine and its reactive metabolites theophylline and theobromine on the differentiating testis. ( Locquet, O; Magre, S; Pollard, I; Solvar, A, 2001) |
| "Previous studies of maternal caffeine use and pregnancy outcome have relied on self-reported use." | 3.70 | Serum caffeine and paraxanthine as markers for reported caffeine intake in pregnancy. ( Clemens, JD; Dersimonian, R; Klebanoff, MA; Levine, RJ; Wilkins, DG, 1998) |
| "8-Phenyltheophylline abolished hypoxia-induced bradycardia and hypertension and produced a nearly 5-fold greater rise in fetal plasma concentrations of corticotropin and approximately a 3-fold greater increase in plasma cortisol levels." | 3.70 | Adenosine modulates corticotropin and cortisol release during hypoxia in fetal sheep. ( Chau, A; Koos, BJ; Rose, JC, 1999) |
| "Whether the consumption of caffeine during pregnancy increases the risk of spontaneous abortion is controversial." | 3.70 | Maternal serum paraxanthine, a caffeine metabolite, and the risk of spontaneous abortion. ( Clemens, JD; DerSimonian, R; Klebanoff, MA; Levine, RJ; Wilkins, DG, 1999) |
| "Oral theophylline treatment may be helpful in controlling severe asthma during pregnancy." | 3.69 | Slow-release theophylline in pregnant asthmatics. ( Riikonen, S; Stenius-Aarniala, B; Teramo, K, 1995) |
| "A 32 year old pregnant woman who had taken large doses of theophylline for asthmatic attack was brought to our emergency medical center with convulsion and respiratory disturbance." | 3.68 | [Severe theophylline toxicity in a pregnant asthmatic patient]. ( Kasagawa, J; Nagahama, H; Nagano, K; Seki, I; Suzuki, Y; Yamanaka, I, 1993) |
| " caused fetal apnea that was reduced from 143 +/- 45." | 3.68 | Influence of prolonged adenosine receptor blockade on fetal sleep and breathing patterns. ( Avital, A; Chernick, V; Jansen, AH; Sitar, DS, 1993) |
| "The purpose of the investigation was to determine the effects of pregnancy on theophylline pharmacokinetics and to clarify the clinical effect of theophylline treatment in cases of threatened anoxemia of foetus." | 3.68 | [Pharmacokinetic examination of theophylline in pregnancy in cases of fetal anoxia]. ( Chmielewski, S; Jankowski, A; Skublicki, S; Szymański, M; Szymański, W, 1992) |
| " The methylxanthines; caffeine, theophylline and theobromine, were administered via drinking water in the proportions occurring in tea, at a dose of 50, 1 and 2 mg/kg body-weight respectively to Wistar albino rats throughout pregnancy and for up to the 14th day of lactation." | 3.68 | The effect of methylxanthines on milk volume and composition, and growth of rat pups. ( Grimble, RF; Hart, AD, 1990) |
| "Sera from 10 subjects in the third trimester of pregnancy and from 10 nonpregnant women were studied to elucidate the mechanism underlying decreased theophylline protein binding during pregnancy." | 3.68 | Characterization of theophylline binding to serum proteins in pregnant and nonpregnant women. ( Atkinson, AJ; Connelly, TJ; Frederiksen, MC; Ruo, TI, 1990) |
| "04% caffeine in the drinking fluid ad libitum before and/or during pregnancy throughout the lactational period, were examined on days 1, 5 and 10." | 3.68 | Maternal caffeine ingestion increases the tyrosine level in neonatal rat cerebrum. ( Nakazawa, K; Tanaka, H, 1990) |
| "Women in the Collaborative Perinatal Project who received theophylline during pregnancy were no more likely to be delivered of a stillborn infant than were women who did not receive theophylline." | 3.68 | Maternal theophylline consumption and the risk of stillbirth. ( Leviton, A; Neff, RK, 1990) |
| "Lesch-Nyhan syndrome involves disorders of both purine and dopamine metabolism." | 3.67 | Assessment of purine-dopamine interactions in 6-hydroxydopamine-lesioned rats: evidence for pre- and postsynaptic influences by adenosine. ( Breese, GR; Criswell, H; Mueller, RA, 1988) |
| "The purpose of this investigation was to determine whether the neurotoxicity of theophylline is altered in advanced pregnancy." | 3.67 | Theophylline neurotoxicity in pregnant rats. ( DeDonato, V; Ramzan, I, 1988) |
| "The effects of pregnancy on the disposition of theophylline were assessed in 10 patients throughout pregnancy and post-partum." | 3.67 | Longitudinal effects of pregnancy on the pharmacokinetics of theophylline. ( Cousins, L; Gardner, MJ; Jusko, WJ; Middleton, E; Schatz, M; Zeiger, R, 1987) |
| "02% caffeine in drinking water ad libitum before and/or during pregnancy were examined on gestational day 21." | 3.67 | Effects of maternal caffeine ingestion on the perinatal cerebrum. ( Arima, M; Nakazawa, K; Tanaka, H, 1987) |
| "The incidence of preeclampsia was reduced among asthmatic patients taking theophylline (one of 85) compared to other asthmatic patients (six of 68, p less than 0." | 3.67 | Incidence of preeclampsia among asthmatic patients lower with theophylline. ( Boike, GM; Bottoms, SF; Dombrowski, MP; Wald, J, 1986) |
| "Theophylline pharmacokinetics were studied serially in five women during and after pregnancy." | 3.67 | Theophylline pharmacokinetics in pregnancy. ( Atkinson, AJ; Chow, MJ; Frederiksen, MC; Ruo, TI, 1986) |
| "Theophylline clearance was prospectively studied in eight pregnant asthmatic patients who were receiving maintenance doses of theophylline." | 3.67 | Theophylline clearance during pregnancy. ( Carter, BL; Driscoll, CE; Smith, GD, 1986) |
| "Characterization of alterations in caffeine elimination during pregnancy is essential in assessing the potential exposure of the fetus to caffeine and its metabolites." | 3.67 | Elimination of chronically consumed caffeine in the pregnant monkey (Macaca fascicularis). ( Geoffroy, S; Gilbert, SG; Klassen, RD; Rice, DC; So, Y; Stavric, B, 1986) |
| "After literature reports linking fibrocystic breast disease (FBD) to methylxanthine ingestion, a pilot study was undertaken to investigate the possible contribution of theophylline to this effect." | 3.67 | Theophylline and fibrocystic breast disease. ( Bullough, B; Hindi-Alexander, MC; London, WM; Middleton, E; Montes, N; Rosner, DH; Zielezny, MA, 1985) |
| "Caffeine disposition was studied over 24 h in rats on the 12th day of pregnancy given 80 mg/kg of drug as a single oral dose or in four divided doses every three hours." | 3.67 | Caffeine disposition after oral administration to pregnant rats. ( Bonati, M; Bortolotti, A; Gaspari, F; Jiritano, L, 1985) |
| "The newborn's potential for xanthine toxic reactions from placental transfer of theophylline or caffeine conversion from theophylline was studied in 12 newborns of asthmatic mothers." | 3.66 | Placental theophylline transfer in pregnant asthmatics. ( Labovitz, E; Spector, S, 1982) |
| "The specific induction of alkaline phosphatase with Tamm-Horsfall glycoprotein, isoproterenol, and theophylline in skin-derived fibroblast cultures from patients with cystic fibrosis permits one to reliably discriminate between cystic fibrosis patients on the one hand, and heterozygotes and normals on the other." | 3.66 | Reliable detection of cystic fibrosis in skin-derived fibroblast cultures. ( Hösli, P; Vogt, E, 1978) |
| " In the meantime, health care providers and pregnant women must work with the information that is available to evaluate the risks and benefits of a particular medication and alternative choices for treatment of asthma or allergy during pregnancy, while considering the potential for adverse effects if the woman with severe or uncontrolled asthma is under-treated." | 2.43 | Safety of asthma and allergy medications in pregnancy. ( Chambers, C, 2006) |
| "Epidemiological studies showed that bronchial asthma is one of the most common diseases which can complicate pregnancy (1-7%)." | 2.42 | General strategy for the management of bronchial asthma in pregnancy. ( Canonica, GW; Cazzola, M; D'Amato, G; D'Amato, M; Liccardi, G; Passalacqua, G, 2003) |
| " These drugs must be administered parenterally and have a half-life of only a few minutes." | 2.40 | Clinical pharmacokinetics of vasodilators. Part II. ( Heintz, B; Kirsten, D; Kirsten, R; Nelson, K, 1998) |
| "Caffeine is a central nervous system stimulant that has come under increasing scrutiny due to its effects on the health and mental health of those who consume it." | 2.37 | Caffeine: implications of recent research for clinical practice. ( Wells, SJ, 1984) |
| "Normal human pregnancy is characterized by vascular refractoriness to AII." | 2.36 | Control of vascular responsiveness during human pregnancy. ( Everett, RB; Gant, NF; MacDonald, PC; Worley, RJ, 1980) |
| "045), with the cumulative intraoperative dosage also increased in the granisetron group (P=0." | 1.51 | Granisetron reduces the need for uterotonics but not sympathomimetics during cesarean delivery. ( Baldauf, HP; Fischer, D; Jennewein, L; Louwen, F; Raimann, FJ; Weber, CF; Zacharowski, K, 2019) |
| " Therefore, we developed a physiologically based pharmacokinetic (PBPK) model to estimate fetal drug exposure throughout pregnancy." | 1.46 | Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model II: Verification of the model for passive placental permeability drugs. ( Unadkat, JD; Zhang, Z, 2017) |
| " Maternal and foetal pharmacokinetic parameters were estimated." | 1.42 | Theophylline Pharmacokinetics in Foetal Sheep: Maternal Metabolic Capacity is the Principal Driver. ( Cherala, G; DuBois, B; Giraud, GD; Jonker, SS; Louey, S, 2015) |
| "A case of a male Kartagener syndrome with exclusively immotile spermatozoa that did not react to the dimethylxanthine theophylline." | 1.42 | Healthy twin live-birth after ionophore treatment in a case of theophylline-resistant Kartagener syndrome. ( Costamoling, W; Duba, HC; Ebner, T; Maurer, M; Mayer, RB; Oppelt, P; Shebl, O, 2015) |
| "The outcome of interest was severe preeclampsia, and exposures were serum paraxanthine (1,7-dimethylxanthine), measured through high-performance liquid chromatography, and CYP1A2 activity, assessed by paraxanthine/caffeine ratios." | 1.42 | Second-Trimester Maternal Serum Paraxanthine, CYP1A2 Activity, and the Risk of Severe Preeclampsia. ( Baker, AM; Eichelberger, KY; Haeri, S; Strauss, RA; Stuebe, AM; Woodham, PC, 2015) |
| "Pre-treatment with nifedipine (10(-8) M), tetraethylammonium (10(-3) M), and theophylline (10(-5) M) attenuated the contracting effect of d- and l-limonene, while in the presence of paxilline (10(-5) M) d- and l-limonene were ineffective." | 1.42 | Effects of d- and l-limonene on the pregnant rat myometrium in vitro. ( Gáspár, R; Hajagos-Tóth, J; Hódi, Á; Seres, AB, 2015) |
| "Theophylline turned out to be a safe, efficient agent for stimulating immotile spermatozoa in patients with retrograde ejaculation." | 1.40 | Healthy live birth using theophylline in a case of retrograde ejaculation and absolute asthenozoospermia. ( Costamoling, W; Ebner, T; Mayer, RB; Moser, M; Oppelt, P; Shebl, O, 2014) |
| "Conducting pharmacokinetic (PK) studies in pregnant women is challenging." | 1.39 | A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women. ( Isoherranen, N; Ke, AB; Nallani, SC; Rostami-Hodjegan, A; Unadkat, JD; Zhao, P, 2013) |
| "Theophylline turned out to be a reliable tool in stimulating testicular spermatozoa after thawing." | 1.37 | Pharmacological stimulation of sperm motility in frozen and thawed testicular sperm using the dimethylxanthine theophylline. ( Arzt, W; Costamoling, W; Ebner, T; Mayer, RB; Shebl, O; Tews, G; Ziehr, S, 2011) |
| "Maternal hypotension is the most frequent complication in spinal anesthesia for Cesarean delivery." | 1.36 | Impact of cafedrine/theodrenaline (Akrinor® ) on therapy of maternal hypotension during spinal anesthesia for Cesarean delivery: a retrospective study. ( Clemens, KE; Heller, AR; Klaschik, E; Quednau, I, 2010) |
| "The prevalence of bronchial asthma, similarly to the normal population, is also increasing among pregnant women." | 1.32 | [Treatment of bronchial asthma in pregnancy]. ( Bártfai, Z; Somoskövi, A; Tamási, L; Tolnay, E, 2003) |
| "The theophylline infusion was begun 30 min prior to and ended 30 min after the completion of the hypoxic insult." | 1.31 | The role of adenosine in regulation of cerebral blood flow during hypoxia in the near-term fetal sheep. ( Blood, AB; Hunter, CJ; Power, GG, 2002) |
| " Experimental studies in pregnant rabbits using Primatene in both low and high dosage resulted in limb reduction defects and other malformations in a significant number of the offspring compared with controls." | 1.31 | Association of sympathomimetic drugs with malformations. ( Drut, RM; Gilbert-Barness, E, 2000) |
| "Adenosine is an established platelet activation suppressor." | 1.31 | Plasma adenosine levels and P-selectin expression on platelets in preeclampsia. ( Araki, T; Kiyokawa, Y; Power, GG; Sawa, R; Suzuki, S; Yoneyama, Y, 2001) |
| "There is a need to modify dosage schedule for these babies." | 1.29 | Kinetics of theophylline in apnea of prematurity in small for gestational age babies. ( Bhakoo, ON; Chaudhuri, M; Garg, SK; Narang, A, 1996) |
| "Theophylline has been used widely in the management of asthma in pregnancy, and the assessment of fetal breathing movements is used routinely for evaluation of fetal status." | 1.29 | Maternal theophylline administration and breathing movements in late-gestation human fetuses. ( Araki, T; Ishikawa, M; Power, GG; Yoneyama, Y, 1996) |
| "Treatment with theophylline did not alter the elevation of plasma [ADO] after dipyridamole infusion, but abolished responses of fetal heart rate to dipyridamole infusion." | 1.28 | Plasma adenosine and cardiovascular responses to dipyridamole in fetal sheep. ( Power, GG; Yoneyama, Y, 1992) |
| " Dose-response curves to the agonists were similar for both age groups." | 1.28 | Cerebrovascular reactivity to adenosine analogues in 0.6-0.7 gestation and near-term fetal sheep. ( Kurth, CD; Wagerle, LC, 1992) |
| "Caffeine has been associated with a number of reproductive and developmental effects in animals and humans." | 1.28 | Somatic development of the infant monkey following in utero exposure to caffeine. ( Gilbert, SG; Rice, DC, 1991) |
| "30%) that did not produce overt maternal toxicity, but the adverse developmental effects in mice were observed at doses that caused reduced maternal water consumption and body weight gain." | 1.28 | The developmental toxicity of orally administered theophylline in rats and mice. ( George, JD; Kimmel, CA; Lindström, P; Marr, MC; Morrissey, RE; Price, CJ; Schwetz, BA, 1990) |
| "Theophylline has been shown to be a potent cardiovascular teratogen in animals, but there has been no evidence linking theophylline with congenital anomalies in infants." | 1.28 | Cardiovascular anomalies associated with prenatal exposure to theophylline. ( Myers, TL; Park, JM; Schmer, V, 1990) |
| "The Rai and Van Ryzin dose-response model proposed for teratology experiments has been characterized for its appropriateness and applicability in modeling the dichotomous response data from developmental toxicity studies." | 1.28 | Characterization of a developmental toxicity dose-response model. ( Faustman, EM; Kimmel, CA; Smith, WP; Wellington, DG, 1989) |
| "Since terbutaline treatment in premature labor has been shown to increase phosphodiesterase activity in the myometrium, the phosphodiesterase-inhibiting effect of theophylline and papaverine on myometrial preparations from pregnant women has been studied." | 1.27 | In vitro study of phosphodiesterase-inhibiting drugs: a complement to beta-sympathomimetic drug therapy in premature labor? ( Andersson, RG; Berg, G; Rydén, G, 1983) |
| " Glucagon did not antagonize the maximal stimulatory effect of insulin, nor did it alter the insulin dose-response curve." | 1.27 | Regulation of peripheral lipogenesis by glucagon. Inability of the hormone to inhibit lipogenesis in rat mammary acini in vitro in the presence or absence of agents which alter its effects on adipocytes. ( Clegg, RA; Robson, NA; Zammit, VA, 1984) |
| "Successful pregnancy is described in a patient with beta-thalassaemia major, transfusion-dependent from four months of age and treated with desferrioxamine from 13 years of age." | 1.27 | Successful pregnancy in beta-thalassaemia major. ( Martin, K, 1983) |
| "24 ml/kg/min) of theophylline is increased in pregnant women, but the half-life (mean 7." | 1.27 | Pharmacokinetics of intravenous theophylline in pregnant patients at term. ( Gonzales Govea, F; Hobbins, JC; Kadar, N; Romero, R, 1983) |
| " For predicting the drug uptake by the suckling infant a pharmacokinetic model was designed allowing estimations of drug uptake by the infant on the basis of the kinetics of the translactal passage and the kinetics of the drug in the infant." | 1.27 | [Pharmacokinetics of drugs from the breast-feeding mother passing into the body of the infant, using theophylline as an example]. ( Brandenburg, G; Reinhardt, D; Richter, O, 1983) |
| " The kinetic parameters of P rats were strikingly similar to NP rats at all TBR dosage levels employed." | 1.27 | Theobromine metabolism and pharmacokinetics in pregnant and nonpregnant Sprague-Dawley rats. ( Shively, CA; Tarka, SM, 1983) |
| "Theophylline was administered by gavage in 13-week studies to B6C3F1 mice (0, 75, 150, 300 mg/kg/day) and F344 rats (0, 37." | 1.27 | Reproductive effects of theophylline in mice and rats. ( Collins, JJ; Gulati, DK; Lamb, JC; Manus, AG; Morrissey, RE, 1988) |
| "The slow disappearance of the arrhythmia is a result of the prolonged half-life of theophylline in the fetus." | 1.27 | [Fetal bigeminus following combined bronchodilator treatment of the mother]. ( Neeb, U, 1986) |
| " The approximate volume of distribution (aVd) and extrapolated peak concentration (Cp0) in the 3 groups were not different." | 1.27 | Theophylline pharmacokinetics in pregnant and lactating rats. ( Ben-Zvi, Z; Brandstetter, Y; Kaplanski, J; van Creveld, C, 1986) |
| "Theophylline was less potent in relaxing the potassium induced contraction." | 1.27 | Effects of theophylline on small human placental arteries in vitro. ( Nielsen-Kudsk, JE, 1985) |
| "Gestational age, gender, duration of treatment, body weight, and Apgar scores were not found to correlate significantly with theophylline clearance." | 1.27 | Factors influencing theophylline disposition in 179 newborns. ( Erkan, NV; Gal, P; Gilman, JT; Hersh, CB; Levine, RS, 1986) |
| "Enprofylline was about three times more potent than theophylline." | 1.27 | Enprofylline and theophylline on small human placental arteries: studies of in vitro effects and mode of action. ( Nielsen-Kudsk, JE, 1985) |
| " Additional clinical features are discussed, including avoidance of dosing errors through careful instruction of all caretakers prior to discharge." | 1.27 | Theophylline toxicity in a preterm infant: selected clinical aspects. ( Komatsu, G; Modanlou, HD; Strauss, AA, 1985) |
| " IBMX by itself, stimulated ornithine decarboxylase (ODC) activity in a dose-response fashion; but the IBMX at concentrations up to 1 mM had no effect on the magnitude of the prolactin-stimulated ODC activity." | 1.26 | Effect of 3-isobutyl-1-methylxanthine on prolactin actions on RNA synthesis, casein synthesis, lipid synthesis and ornithine decarboxylase activity in mouse mammary gland explants. ( Rillema, JA; Wing, LY, 1982) |
| "All had central sleep apnea, three had hypoventilation, and none had obstructive apnea observed on polygraphic recordings." | 1.26 | Episodic complete airway obstruction in infants. ( Kelly, DH; Shannon, DC, 1981) |
| "theophylline and quinine, were found to reduce by 40-50% the rate of [3H] leucine incorporation into casein in mammary gland explants from midpregnant mice." | 1.26 | Possible interaction of cyclic nucleotides with the prolactin stimulation of casein synthesis in mouse mammary gland explants. ( Rillema, JA, 1976) |
| "When indomethacin was added to the myometrial extracts, the activity of the high Km phosphodiesterase was competitively inhibited, with an average Ki of 200 muM; the low Km enzyme was noncompetitively inhibited with an average Ki of 110 muM." | 1.26 | Effect of Indomethacin on cyclic AMP phosphodiesterase activity in myometrium from pregnant rhesus monkeys. ( Beatty, CH; Bocek, RM; Novy, MJ; Young, MK, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 243 (63.61) | 18.7374 |
| 1990's | 58 (15.18) | 18.2507 |
| 2000's | 41 (10.73) | 29.6817 |
| 2010's | 36 (9.42) | 24.3611 |
| 2020's | 4 (1.05) | 2.80 |
| Authors | Studies |
|---|---|
| Polinski, KJ | 1 |
| Purdue-Smithe, A | 1 |
| Robinson, SL | 1 |
| Zhao, SK | 1 |
| Schliep, KC | 1 |
| Silver, RM | 1 |
| Guan, W | 1 |
| Schisterman, EF | 1 |
| Mumford, SL | 1 |
| Yeung, EH | 1 |
| Sultan, K | 1 |
| Zamir, A | 1 |
| Ashraf, W | 1 |
| Imran, I | 1 |
| Saeed, H | 1 |
| Rehman, AU | 1 |
| Majeed, A | 1 |
| Rasool, MF | 1 |
| Sandi-Monroy, NL | 1 |
| Musanovic, S | 1 |
| Zhu, D | 1 |
| Szabó, Z | 1 |
| Vogl, A | 1 |
| Reeka, N | 1 |
| Eibner, K | 1 |
| Bundschu, K | 1 |
| Gagsteiger, F | 1 |
| Kranke, P | 4 |
| Geldner, G | 2 |
| Kienbaum, P | 1 |
| Gerbershagen, HJ | 1 |
| Chappell, D | 2 |
| Wallenborn, J | 1 |
| Huljic, S | 2 |
| Koch, T | 2 |
| Keller, T | 2 |
| Weber, S | 1 |
| Kunitz, O | 1 |
| Linstedt, U | 1 |
| Eberhart, LHJ | 1 |
| Gleason, JL | 1 |
| Tekola-Ayele, F | 1 |
| Sundaram, R | 1 |
| Hinkle, SN | 1 |
| Vafai, Y | 1 |
| Buck Louis, GM | 1 |
| Gerlanc, N | 1 |
| Amyx, M | 1 |
| Bever, AM | 1 |
| Smarr, MM | 1 |
| Robinson, M | 1 |
| Kannan, K | 1 |
| Grantz, KL | 1 |
| Eberhart, L | 2 |
| Marggraf, K | 1 |
| Correia-Branco, A | 1 |
| Keating, E | 2 |
| Martel, F | 2 |
| Helf, A | 1 |
| Gayer, J | 1 |
| Raimann, FJ | 1 |
| Baldauf, HP | 1 |
| Louwen, F | 1 |
| Jennewein, L | 1 |
| Fischer, D | 1 |
| Zacharowski, K | 1 |
| Weber, CF | 1 |
| Zafar, A | 1 |
| Lee, J | 1 |
| Yesmin, S | 1 |
| Paget, MB | 1 |
| Bailey, CJ | 1 |
| Murray, HE | 1 |
| Downing, R | 1 |
| Mogollon, JA | 1 |
| Bujold, E | 1 |
| Lemieux, S | 1 |
| Bourdages, M | 1 |
| Blanchet, C | 1 |
| Bazinet, L | 1 |
| Couillard, C | 1 |
| Noël, M | 1 |
| Dodin, S | 1 |
| Ebner, T | 3 |
| Shebl, O | 3 |
| Mayer, RB | 3 |
| Moser, M | 1 |
| Costamoling, W | 3 |
| Oppelt, P | 2 |
| Tsuchida, T | 1 |
| Matsuse, H | 1 |
| Schmauss, C | 1 |
| Lee-McDermott, Z | 1 |
| Medina, LR | 1 |
| He, H | 1 |
| Chen, F | 1 |
| Ni, W | 1 |
| Li, J | 1 |
| Zhang, Y | 1 |
| Wierzejska, R | 1 |
| Jarosz, M | 1 |
| Siuba, M | 1 |
| Sawicki, W | 1 |
| Bain, E | 1 |
| Pierides, KL | 1 |
| Clifton, VL | 1 |
| Hodyl, NA | 1 |
| Stark, MJ | 1 |
| Crowther, CA | 1 |
| Middleton, P | 1 |
| Klebanoff, MA | 5 |
| Keim, SA | 2 |
| DuBois, B | 1 |
| Louey, S | 1 |
| Giraud, GD | 1 |
| Cherala, G | 1 |
| Jonker, SS | 1 |
| Maurer, M | 1 |
| Duba, HC | 1 |
| Eichelberger, KY | 1 |
| Baker, AM | 1 |
| Woodham, PC | 1 |
| Haeri, S | 1 |
| Strauss, RA | 1 |
| Stuebe, AM | 1 |
| Yu, T | 1 |
| Campbell, SC | 1 |
| Stockmann, C | 1 |
| Tak, C | 1 |
| Schoen, K | 1 |
| Clark, EA | 1 |
| Varner, MW | 3 |
| Spigarelli, MG | 1 |
| Sherwin, CM | 1 |
| Hajagos-Tóth, J | 2 |
| Hódi, Á | 1 |
| Seres, AB | 2 |
| Gáspár, R | 3 |
| Askenazi, D | 1 |
| Zhang, Z | 1 |
| Unadkat, JD | 2 |
| Hernández-Díaz, S | 1 |
| Mitchell, AA | 1 |
| Kelley, KE | 1 |
| Calafat, AM | 1 |
| Hauser, R | 1 |
| Schatz, M | 5 |
| Dombrowski, MP | 4 |
| Stiefelhagen, P | 1 |
| Newman, RB | 2 |
| Momirova, V | 1 |
| Wise, R | 2 |
| Landon, M | 2 |
| Rouse, DJ | 1 |
| Lindheimer, M | 2 |
| Caritis, SN | 2 |
| Sheffield, J | 1 |
| Miodovnik, M | 2 |
| Wapner, RJ | 2 |
| O'Sullivan, MJ | 2 |
| Conway, DL | 2 |
| Gustafsson, J | 1 |
| Worth, H | 1 |
| Gillissen, A | 1 |
| Hardy-Fairbanks, AJ | 1 |
| Baker, ER | 1 |
| Coney, AM | 1 |
| Marshall, JM | 1 |
| George, EM | 1 |
| Cockrell, K | 1 |
| Adair, TH | 1 |
| Granger, JP | 1 |
| Klukovits, A | 2 |
| Verli, J | 2 |
| Falkay, G | 2 |
| Clemens, KE | 1 |
| Quednau, I | 1 |
| Heller, AR | 1 |
| Klaschik, E | 1 |
| Laughon, SK | 1 |
| Powers, RW | 1 |
| Roberts, JM | 1 |
| Parana, S | 1 |
| Catov, J | 1 |
| Kleine-Brüggeney, M | 1 |
| Stamer, UM | 1 |
| Tews, G | 1 |
| Ziehr, S | 1 |
| Arzt, W | 1 |
| Fiala, A | 1 |
| Furgler, G | 1 |
| Baumgartner, E | 1 |
| Paal, P | 1 |
| Kneser, J | 1 |
| Wehmeier, P | 1 |
| Lichtinghagen, R | 1 |
| Hoeper, MM | 1 |
| Kielstein, JT | 1 |
| Kormányos, Z | 1 |
| Ducza, E | 1 |
| Ke, AB | 1 |
| Nallani, SC | 1 |
| Zhao, P | 1 |
| Rostami-Hodjegan, A | 1 |
| Isoherranen, N | 1 |
| León, D | 3 |
| Albasanz, JL | 3 |
| Ruíz, MA | 3 |
| Fernández, M | 1 |
| Martín, M | 3 |
| Blood, AB | 1 |
| Hunter, CJ | 1 |
| Power, GG | 7 |
| Young, G | 1 |
| Somoskövi, A | 1 |
| Tamási, L | 1 |
| Bártfai, Z | 1 |
| Tolnay, E | 1 |
| Liccardi, G | 1 |
| Cazzola, M | 1 |
| Canonica, GW | 1 |
| D'Amato, M | 1 |
| D'Amato, G | 1 |
| Passalacqua, G | 1 |
| WERNZE, H | 1 |
| JAMES, WF | 1 |
| JOHNSON, AP | 1 |
| PATTERSON, RE | 1 |
| BAER, H | 1 |
| MARZETTI, L | 3 |
| BENAGIANO, G | 2 |
| KNOCHE, C | 1 |
| KOENIG, J | 1 |
| Bracken, MB | 3 |
| Triche, EW | 2 |
| Belanger, K | 2 |
| Saftlas, A | 1 |
| Beckett, WS | 1 |
| Leaderer, BP | 1 |
| Grosso, L | 1 |
| Triche, E | 1 |
| Thom, EA | 1 |
| Mabie, W | 1 |
| McNellis, D | 1 |
| Hauth, JC | 1 |
| Leveno, KJ | 1 |
| Meis, P | 1 |
| Beckmann, I | 1 |
| Efraim, SB | 1 |
| Vervoort, M | 1 |
| Visser, W | 1 |
| Wallenburg, HC | 1 |
| Gluck, JC | 1 |
| Gluck, PA | 1 |
| Broscheit, J | 1 |
| Eichelbroenner, O | 1 |
| Greim, C | 1 |
| Bussen, S | 1 |
| Osur, SL | 1 |
| Iglesias, I | 1 |
| Suzuki, C | 1 |
| Yoshioka, K | 1 |
| Itoh, S | 1 |
| Kawarasaki, T | 1 |
| Kikuchi, K | 1 |
| Chambers, C | 1 |
| Grosso, LM | 1 |
| Benowitz, NL | 1 |
| Holford, TR | 1 |
| Aniset, L | 1 |
| Konrad, C | 1 |
| Schley, M | 1 |
| Lemos, C | 1 |
| Azevedo, I | 1 |
| Wessler, I | 1 |
| Herschel, S | 1 |
| Bittinger, F | 1 |
| Kirkpatrick, CJ | 1 |
| Infante-Rivard, C | 1 |
| ten Tusscher, GW | 1 |
| Guchelaar, HJ | 1 |
| Koch, J | 1 |
| Ilsen, A | 1 |
| Vulsma, T | 1 |
| Westra, M | 1 |
| van der Slikke, JW | 1 |
| Olie, K | 1 |
| Koppe, JG | 1 |
| Boylan, SM | 1 |
| Cade, JE | 1 |
| Kirk, SF | 1 |
| Greenwood, DC | 1 |
| White, KL | 1 |
| Shires, S | 1 |
| Simpson, NA | 1 |
| Wild, CP | 1 |
| Hay, AW | 1 |
| Lamers, WH | 1 |
| Zonneveld, D | 1 |
| Charles, R | 1 |
| Hernandez, E | 1 |
| Angell, CS | 1 |
| Johnson, JW | 1 |
| Weir, GC | 1 |
| Clore, ET | 1 |
| Zmachinski, CJ | 1 |
| Bonner-Weir, S | 1 |
| Volpe, JJ | 1 |
| Mathieu, M | 1 |
| Cerrina, J | 1 |
| Simonneau, G | 1 |
| Duroux, P | 1 |
| Herman, D | 1 |
| Vidart, JN | 1 |
| Stablein, JJ | 1 |
| Lockey, RF | 1 |
| Bukowskyj, M | 1 |
| Nakatsu, K | 1 |
| Munt, PW | 1 |
| Beyer, C | 1 |
| Canchola, E | 1 |
| Rillema, JA | 5 |
| Wing, LY | 1 |
| Greene, RM | 1 |
| MacAndrew, VI | 1 |
| Lloyd, MR | 1 |
| Hong, SL | 1 |
| Ziegler, B | 1 |
| Kohnert, KD | 1 |
| Noack, S | 1 |
| Hahn, HJ | 1 |
| Spector, SL | 1 |
| Pienkowski, MM | 1 |
| Ellinwood, WE | 1 |
| Brenner, RM | 1 |
| Hess, DL | 1 |
| Resko, JA | 1 |
| Currie, WB | 1 |
| Gant, NF | 3 |
| Worley, RJ | 3 |
| Everett, RB | 3 |
| MacDonald, PC | 3 |
| Wilde, CJ | 1 |
| Kuhn, NJ | 1 |
| Bellino, FL | 2 |
| Hussa, RO | 7 |
| Stirt, JA | 1 |
| Sullivan, SF | 1 |
| Avivi, A | 1 |
| Shemesh, M | 1 |
| Lindner, HR | 2 |
| Tomita, K | 1 |
| McCoshen, JA | 1 |
| Fernandez, CS | 1 |
| Tyson, JE | 1 |
| Hanover, JA | 1 |
| Elting, J | 1 |
| Mintz, GR | 1 |
| Lennarz, WJ | 1 |
| Ferre, F | 5 |
| Breuiller, M | 4 |
| Cedard, L | 5 |
| Hirata, Y | 1 |
| Sueoka, S | 1 |
| Uchihashi, M | 1 |
| Yoshimoto, Y | 1 |
| Fujita, T | 1 |
| Matsukura, S | 1 |
| Motoyama, T | 1 |
| Rabe, T | 1 |
| Scheurer, A | 1 |
| Müller, A | 1 |
| Runnebaum, B | 1 |
| Berg, G | 2 |
| Andersson, RG | 2 |
| Rydén, G | 2 |
| Daval, JL | 2 |
| Barberis, C | 1 |
| Vert, P | 2 |
| Miller, M | 1 |
| Opheim, KE | 1 |
| Raisys, VA | 1 |
| Motulsky, AG | 1 |
| Rajchgot, P | 1 |
| MacLeod, S | 1 |
| Robson, NA | 2 |
| Clegg, RA | 2 |
| Zammit, VA | 2 |
| Wells, SJ | 1 |
| Branscomb, BV | 1 |
| Nakatsuka, T | 1 |
| Hanada, S | 1 |
| Fujii, T | 3 |
| Martin, K | 1 |
| Hendeles, L | 1 |
| Weinberger, M | 1 |
| Baird-Lambert, J | 2 |
| Doyle, PE | 2 |
| Thomas, D | 2 |
| Jager-Roman, E | 2 |
| Cvejic, M | 2 |
| Buchanan, N | 2 |
| Gabrielsson, JL | 1 |
| Paalzow, LK | 1 |
| Nordström, L | 1 |
| Tanaka, H | 6 |
| Nakazawa, K | 6 |
| Arima, M | 3 |
| Iwasaki, S | 1 |
| Sato, Y | 1 |
| Sunaga, S | 1 |
| Brazier, JL | 2 |
| Ribon, B | 1 |
| Desage, M | 1 |
| Comet, F | 1 |
| Lièvre, M | 1 |
| Berland, M | 1 |
| Salle, B | 2 |
| Tebbutt, IH | 1 |
| Teare, AJ | 1 |
| Meek, JH | 1 |
| Mallett, KA | 1 |
| Hawkins, DF | 1 |
| Dorrbecker, BR | 3 |
| Mercik, SH | 1 |
| Kramer, PA | 3 |
| Pajor, A | 1 |
| Zsolnai, B | 1 |
| Reiche, R | 1 |
| Frey, HH | 1 |
| Romero, R | 1 |
| Kadar, N | 1 |
| Gonzales Govea, F | 1 |
| Hobbins, JC | 1 |
| van Leeuwen, A | 1 |
| Festenstein, H | 1 |
| van Rood, JJ | 1 |
| Reinhardt, D | 1 |
| Richter, O | 1 |
| Brandenburg, G | 1 |
| Shively, CA | 1 |
| Tarka, SM | 1 |
| Agren, A | 1 |
| Andersson, A | 3 |
| Björkén, C | 1 |
| Groth, CG | 2 |
| Gunnarsson, R | 1 |
| Hellerström, C | 2 |
| Lindmark, G | 1 |
| Lundqvist, G | 1 |
| Petersson, B | 2 |
| Swenne, I | 1 |
| Kervran, A | 2 |
| Randon, J | 1 |
| Sérey, CT | 1 |
| Saling, E | 1 |
| Zenk, KE | 1 |
| Ansari, A | 1 |
| Salem, FA | 1 |
| Horowitz, DA | 1 |
| Jablonski, WJ | 1 |
| Mehta, KA | 1 |
| Labovitz, E | 1 |
| Spector, S | 1 |
| Arnaud, MJ | 1 |
| Bracco, I | 1 |
| Welsch, C | 1 |
| Brashear, RE | 1 |
| Veng-Pedersen, P | 1 |
| Rhodes, ML | 1 |
| Smith, CN | 1 |
| Kelly, DH | 1 |
| Shannon, DC | 1 |
| Berlin, CM | 1 |
| Jarboe, CH | 1 |
| Cook, LN | 1 |
| Malesic, I | 1 |
| Fleischaker, J | 1 |
| Pollowitz, JA | 1 |
| Schwarz, R | 1 |
| Retzke, U | 1 |
| Lauckner, W | 1 |
| Sleiman, C | 1 |
| Mal, H | 1 |
| Roué, C | 1 |
| Fournier, M | 1 |
| Pariente, R | 1 |
| Lee, PD | 1 |
| Conover, CA | 1 |
| Powell, DR | 1 |
| Stenius-Aarniala, B | 1 |
| Riikonen, S | 1 |
| Teramo, K | 1 |
| Ward, ME | 1 |
| Musa, MN | 1 |
| Bailey, L | 1 |
| Grammatopoulos, D | 1 |
| Milton, NG | 1 |
| Hillhouse, EW | 1 |
| Wilkinson, JM | 1 |
| Pollard, I | 2 |
| Nagahama, H | 1 |
| Nagano, K | 1 |
| Yamanaka, I | 1 |
| Kasagawa, J | 1 |
| Seki, I | 1 |
| Suzuki, Y | 1 |
| Liu, X | 1 |
| Brendel, MD | 1 |
| Klitscher, D | 1 |
| Brandhorst, H | 1 |
| Hering, BJ | 1 |
| Federlin, KF | 1 |
| Bretzel, RG | 1 |
| Avital, A | 1 |
| Jansen, AH | 1 |
| Sitar, DS | 1 |
| Chernick, V | 1 |
| Konduri, GG | 2 |
| Gervasio, CT | 2 |
| Theodorou, AA | 1 |
| Gazca Aguilar, A | 1 |
| del Río Navarro, B | 1 |
| Sienra Monge, JJ | 1 |
| Linares Zapien, FJ | 1 |
| Koos, BJ | 3 |
| Chau, A | 2 |
| Ogunyemi, D | 1 |
| Chaudhuri, M | 1 |
| Garg, SK | 1 |
| Narang, A | 1 |
| Bhakoo, ON | 1 |
| Alexandrov, VA | 1 |
| Bespalov, VG | 1 |
| Petrov, AS | 1 |
| Troyan, DN | 1 |
| Ishikawa, M | 1 |
| Yoneyama, Y | 4 |
| Araki, T | 3 |
| Ball, KT | 1 |
| Gunn, TR | 1 |
| Gluckman, PD | 1 |
| Mital, S | 1 |
| Rotta, AT | 1 |
| Forman, K | 1 |
| Reiling, BA | 1 |
| Drackley, JK | 1 |
| Grum, LR | 1 |
| Berger, LL | 1 |
| Smeaton, TC | 1 |
| Sultana, S | 1 |
| Levine, RJ | 3 |
| Dersimonian, R | 2 |
| Clemens, JD | 3 |
| Wilkins, DG | 3 |
| Kirsten, R | 1 |
| Nelson, K | 1 |
| Kirsten, D | 1 |
| Heintz, B | 1 |
| Rose, JC | 1 |
| Suzuki, S | 3 |
| Watson, CS | 1 |
| White, SE | 1 |
| Homan, JH | 1 |
| Fraher, L | 1 |
| Brien, JF | 1 |
| Bocking, AD | 1 |
| Eskenazi, B | 1 |
| Schult, K | 1 |
| Katerkamp, A | 1 |
| Trau, D | 1 |
| Grawe, F | 1 |
| Cammann, K | 1 |
| Meusel, M | 1 |
| Ibba, RM | 1 |
| Zoppi, MA | 1 |
| Floris, M | 1 |
| Putzolu, M | 1 |
| Monni, G | 1 |
| Todde, PF | 1 |
| Sardu, G | 1 |
| Jester, DM | 1 |
| Grant, MM | 1 |
| Gilbert-Barness, E | 1 |
| Drut, RM | 1 |
| Shibata, M | 1 |
| Wachi, M | 1 |
| Kawaguchi, M | 1 |
| Kojima, J | 1 |
| Onodera, K | 1 |
| Tan, KS | 1 |
| Thomson, NC | 1 |
| Giussani, DA | 1 |
| Gardner, DS | 1 |
| Cox, DT | 1 |
| Fletcher, AJ | 1 |
| Sawa, R | 2 |
| Kiyokawa, Y | 1 |
| Locquet, O | 1 |
| Solvar, A | 1 |
| Magre, S | 1 |
| Yoneyama, K | 1 |
| Klöck, FK | 1 |
| Chantraine, H | 1 |
| Scoggin, CH | 1 |
| Webb, FT | 1 |
| Story, MT | 3 |
| Pattillo, RA | 5 |
| Jack, PM | 3 |
| Milner, RD | 3 |
| Loizzi, RF | 2 |
| de Pont, JJ | 1 |
| Bonting, SL | 1 |
| Smith, RD | 1 |
| Schwartz, AL | 4 |
| Rall, TW | 2 |
| Raiha, NC | 2 |
| Buckle, JW | 1 |
| Nathanielsz, PW | 3 |
| Hussa, O | 1 |
| Bocek, RM | 2 |
| Beatty, CH | 2 |
| Burstein, S | 1 |
| Gagnon, G | 1 |
| Hunter, SA | 1 |
| Maudsley, DV | 1 |
| Fisher, DL | 1 |
| Gunaga, KP | 1 |
| Kuć, A | 1 |
| Skrzydlewski, Z | 1 |
| Anderson, LD | 1 |
| Maeyama, M | 1 |
| Saita, B | 1 |
| Ichihara, K | 1 |
| Munemura, M | 1 |
| Mori, N | 1 |
| Speake, BK | 1 |
| Dils, R | 1 |
| Mayer, RJ | 1 |
| Peck, WA | 1 |
| Dowling, I | 1 |
| Young, MK | 1 |
| Novy, MJ | 1 |
| Mitznegg, P | 1 |
| Schubert, E | 1 |
| Carl, H | 1 |
| Schut, HA | 1 |
| Townsley, JD | 1 |
| Ruoff, HJ | 1 |
| Mathison, R | 1 |
| Lederis, K | 1 |
| Kang, ES | 1 |
| Kemp, RG | 1 |
| de Pariente, D | 1 |
| Yamaguchi, R | 1 |
| Matsuda, T | 1 |
| Nakano, Y | 1 |
| Kyuma, M | 1 |
| Nishikawa, Y | 1 |
| Takenaka, A | 1 |
| Oshima, K | 1 |
| Shaw, R | 1 |
| Cameron, JA | 1 |
| Ruckert, AC | 1 |
| Scheuermann, KW | 1 |
| Soyka, LF | 1 |
| Huot, RI | 1 |
| Foidart, JM | 1 |
| Stromberg, K | 1 |
| Melvin, GR | 1 |
| Aceto, T | 1 |
| Barlow, J | 1 |
| Munson, D | 1 |
| Wierda, D | 1 |
| Peabody, JL | 1 |
| Currin, MR | 1 |
| Korzhova, VV | 1 |
| Kiriushchenkov, AP | 1 |
| Dasta, J | 1 |
| Arwood, LL | 1 |
| Dasta, JF | 1 |
| Friedman, C | 1 |
| Hösli, P | 1 |
| Vogt, E | 1 |
| Metz, G | 1 |
| Specker, M | 1 |
| Sterner, W | 1 |
| Heisler, E | 1 |
| Grahwit, G | 1 |
| Lippert, TH | 3 |
| Cloeren, SE | 3 |
| Fridrich, R | 3 |
| Tobler, HJ | 1 |
| Bänninger, U | 1 |
| Grosspietzsch, R | 1 |
| Husstedt, W | 1 |
| von Klitzing, L | 1 |
| Endell, W | 1 |
| Klinik, F | 1 |
| Oberheuser, F | 1 |
| Amato, PA | 1 |
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| Sodoyez, JC | 1 |
| Turkelson, CM | 1 |
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| Rosenthal, C | 1 |
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| Bidet, R | 1 |
| Steinling, M | 1 |
| Cretti, A | 1 |
| Jaworski, S | 1 |
| Steinetz, BG | 1 |
| Butler, MC | 1 |
| Sawyer, WK | 1 |
| O'Byrne, EM | 1 |
| Giannina, T | 1 |
| Yurchak, AM | 1 |
| Jusko, WJ | 2 |
| Szymański, W | 1 |
| Jankowski, A | 1 |
| Chmielewski, S | 1 |
| Szymański, M | 1 |
| Skublicki, S | 1 |
| McNamara, JP | 1 |
| Becker-Khaleel, B | 1 |
| Parmley, KL | 1 |
| Suzue, T | 1 |
| Schollenberger, A | 1 |
| Degórski, A | 1 |
| Bielecki, W | 1 |
| Stempniak, M | 1 |
| Omarini, D | 3 |
| Barzago, MM | 3 |
| Aramayona, J | 2 |
| Bortolotti, A | 3 |
| Lucchini, G | 1 |
| Bonati, M | 4 |
| Vadász, I | 1 |
| Shurtz-Swirski, R | 1 |
| Cohen, Y | 1 |
| Barnea, ER | 1 |
| Kurth, CD | 1 |
| Wagerle, LC | 1 |
| Aramayona, JJ | 1 |
| Kovác, R | 1 |
| Gáboriková, V | 1 |
| Malickayová, N | 1 |
| Stencl, J | 1 |
| Takeuchi, Y | 1 |
| Sakakibara, R | 1 |
| Ishiguro, M | 1 |
| Tamura, RN | 1 |
| Cox, GS | 1 |
| Upton, RA | 1 |
| Gilbert, SG | 3 |
| Rice, DC | 3 |
| Bissonnette, JM | 2 |
| Hohimer, AR | 2 |
| Knopp, SJ | 2 |
| Mehta, PN | 1 |
| Panitch, HB | 1 |
| Wolfson, MR | 1 |
| Shaffer, TH | 1 |
| Matsuda, K | 1 |
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| Lindström, P | 1 |
| Morrissey, RE | 2 |
| George, JD | 1 |
| Price, CJ | 1 |
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| Park, JM | 1 |
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| Greenberger, PA | 2 |
| Frederiksen, MC | 3 |
| Connelly, TJ | 1 |
| Ruo, TI | 2 |
| Atkinson, AJ | 2 |
| Neff, RK | 1 |
| Leviton, A | 1 |
| Chao, CR | 1 |
| Notoroberto, NF | 1 |
| Tehrani, MH | 1 |
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| Thomas, PJ | 1 |
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| Harman, I | 1 |
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| Handwerger, S | 2 |
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| Faustman, EM | 1 |
| Wellington, DG | 1 |
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| Uszyński, W | 1 |
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| Raye, JR | 2 |
| Collins, JJ | 1 |
| Lamb, JC | 1 |
| Manus, AG | 1 |
| Gulati, DK | 1 |
| Reuhl, KR | 1 |
| Stavric, B | 2 |
| Fielder, PJ | 1 |
| Talamantes, F | 1 |
| Gardner, MJ | 1 |
| Cousins, L | 1 |
| Zeiger, R | 1 |
| Middleton, E | 2 |
| Iliou, JP | 1 |
| Demarne, Y | 1 |
| de Fenoyl, O | 1 |
| Ascher, E | 1 |
| Texier, F | 1 |
| Rochemaure, J | 1 |
| Guérin, JM | 1 |
| Meyer, P | 1 |
| Habib, Y | 1 |
| Bottoms, SF | 1 |
| Boike, GM | 1 |
| Wald, J | 1 |
| Chow, MJ | 1 |
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| Driscoll, CE | 1 |
| Smith, GD | 1 |
| Zabegal'skaia, ZK | 1 |
| Nuzov, BG | 1 |
| Neeb, U | 1 |
| Brandstetter, Y | 1 |
| Kaplanski, J | 1 |
| van Creveld, C | 1 |
| Ben-Zvi, Z | 1 |
| Scott, NR | 1 |
| Chakraborty, J | 1 |
| Marks, V | 1 |
| So, Y | 1 |
| Klassen, RD | 1 |
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| Randall, JL | 1 |
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| Gilbert, EF | 1 |
| Bruyers, H | 1 |
| Optiz, JM | 1 |
| Bucher, HU | 1 |
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| Nielsen-Kudsk, JE | 2 |
| Gilman, JT | 1 |
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| Levine, RS | 1 |
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| Baggett, B | 1 |
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| Marsh, JM | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cafedrin/Theodrenalin (Akrinor®) Versus Ephedrine for Treatment of Hypotension in the Peri-operative Phase in Inpatient Setting: a Multicenter, Prospective, Non-interventional Study[NCT02893241] | 2,013 participants (Actual) | Observational | 2016-04-30 | Completed | |||
| Effect of Granisetron on Usage of Sympathomimetics During Caesarean Section - a Retrospective Analysis[NCT03318536] | 240 participants (Actual) | Observational | 2017-10-05 | Completed | |||
| Assessment of Blood Pressure and Endothelial Function Pregnancy After Acute and Daily Consumption Flavanol-rich Chocolate Among Healthy Pregnant Women: a Pilot Randomized Controlled Trial[NCT01659060] | Phase 2 | 44 participants (Actual) | Interventional | 2008-07-31 | Completed | ||
| General Anesthesia in Obstetric Patients for Cesarean Section, Maternal and Perinatal Outcomes[NCT06160583] | 5,000 participants (Actual) | Observational [Patient Registry] | 2023-11-12 | Active, not recruiting | |||
| [NCT00000578] | Phase 3 | 0 participants | Interventional | 1994-04-30 | Completed | ||
| Effects of Breathing Exercises on Asthmatic Pregnant Females[NCT04674943] | 24 participants (Actual) | Interventional | 2020-09-25 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
42 reviews available for theophylline and Pregnancy
| Article | Year |
|---|---|
Clinical pharmacokinetics of terbutaline in humans: a systematic review.
Topics: Administration, Intravenous; Asthma; Female; Humans; Kinetics; Pregnancy; Terbutaline; Theophylline | 2023 |
[Pregnancy and bronchial asthma].
Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Albuterol; Asthma; Bronchodilator A | 2014 |
Interventions for managing asthma in pregnancy.
Topics: Adrenal Cortex Hormones; Algorithms; Anti-Asthmatic Agents; Asthma; Beclomethasone; Female; Humans; | 2014 |
Clinical practice. Asthma in pregnancy.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Asthmatic Agents | 2009 |
Neonatal energy substrate production.
Topics: Energy Metabolism; Female; Fetal Growth Retardation; Gluconeogenesis; Glucose; Humans; Infant, Newbo | 2009 |
[Bronchial asthma in pregnant women].
Topics: Administration, Oral; Adrenal Cortex Hormones; Adrenergic Agonists; Asthma; Bronchodilator Agents; F | 2010 |
Asthma in pregnancy: pathophysiology, diagnosis and management.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Anti-Asthm | 2010 |
[Prophylaxis and therapy of postdural puncture headache--a critical evaluation of treatment options].
Topics: Adrenocorticotropic Hormone; Adult; Analgesics; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthe | 2011 |
Leg cramps.
Topics: Bandages; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Leg; Muscle Cramp; P | 2002 |
General strategy for the management of bronchial asthma in pregnancy.
Topics: Adrenergic beta-Agonists; Adult; Androstadienes; Anesthesia, Local; Anesthesia, Obstetrical; Asthma; | 2003 |
NAEPP expert panel report. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update.
Topics: Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Adult; Animals; Anti-Ast | 2005 |
Asthma controller therapy during pregnancy.
Topics: Abnormalities, Drug-Induced; Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-Ag | 2005 |
The management of asthma and rhinitis during pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Anti-Asthmati | 2005 |
Safety of asthma and allergy medications in pregnancy.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Allergic Agents; Anti-Asthmatic Agents; Asth | 2006 |
[Ephedrine as alternative to Akrinor in regional obstetric anesthesia].
Topics: Acidosis; Adult; Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, Obstetrical; Cardiovascul | 2006 |
Theophylline reassessed.
Topics: Acidosis; Aging; Allopurinol; Animals; Anti-Bacterial Agents; Breast Feeding; Bronchodilator Agents; | 1984 |
Reciprocal relationship between pregnancy and pulmonary disease. State of the art.
Topics: Adrenergic beta-Agonists; Alcohol Drinking; Anti-Anxiety Agents; Anti-Bacterial Agents; Anti-Infecti | 1984 |
Control of vascular responsiveness during human pregnancy.
Topics: 20-alpha-Dihydroprogesterone; Angiotensin II; Aspirin; Blood Vessels; Cyclic AMP; Female; Humans; Hy | 1980 |
Aminophylline.
Topics: Adult; Aminophylline; Anesthesia; Animals; Anticonvulsants; Arrhythmias, Cardiac; Asthma; Biotransfo | 1981 |
Perinatal pharmacology.
Topics: Biotransformation; Female; Fetus; Glucocorticoids; Humans; Infant, Newborn; Infant, Newborn, Disease | 1983 |
Caffeine: implications of recent research for clinical practice.
Topics: Abnormalities, Drug-Induced; Affective Symptoms; Animals; Blood Pressure; Brain; Caffeine; Child; De | 1984 |
The difficult asthmatic.
Topics: Asthma; Diabetes Complications; Diagnosis, Differential; Dyspnea, Paroxysmal; Female; Gastroesophage | 1984 |
An overview of perinatal clinical pharmacology.
Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digo | 1981 |
[Asthma and its treatment during pregnancy].
Topics: Adrenal Cortex Hormones; Asthma; Female; Fetal Hypoxia; Humans; Infant, Newborn; Pregnancy; Pregnanc | 1995 |
Regulation and function of insulin-like growth factor-binding protein-1.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cattle; Cyclic AMP; Female; Gene Expression; Genes; | 1993 |
Clinical pharmacokinetics of lithium.
Topics: Aged; Benzothiadiazines; Contraindications; Diuretics; Drug Interactions; Drug Monitoring; Female; H | 1994 |
Clinical pharmacokinetics of vasodilators. Part II.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Alprostadil; Amrinone; Carbazoles; Carvedilo | 1998 |
Asthma in pregnancy.
Topics: Adrenergic beta-Agonists; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchodilator Ag | 2000 |
The efficacy and safety of asthma medications during pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Asthmatic Agent | 2001 |
[Possibilities and limits of the intrauterine reanimation (author's transl)].
Topics: Acid-Base Equilibrium; Adrenergic beta-Agonists; Adult; Animals; Dextrans; Electrocardiography; Fema | 1975 |
Effects of methylxanthines on the fetus.
Topics: Animals; Caffeine; Cyclic AMP; Female; Fetus; Humans; Intestinal Absorption; Kinetics; Labor, Obstet | 1979 |
Transcutaneous oxygen measurement to evaluate drug effects.
Topics: Anesthesia, Obstetrical; Apnea; Electrodes; Female; Fetal Monitoring; Humans; Infant, Newborn; Infan | 1979 |
Pharmacology of the neonate.
Topics: Acetaminophen; Adsorption; Aminoglycosides; Barbiturates; Benzodiazepines; Benzothiadiazines; Biolog | 1979 |
The theophylline dilemma.
Topics: Administration, Oral; Adult; Aged; Asthma; Bronchitis; Delayed-Action Preparations; Female; Humans; | 1992 |
Pharmacokinetic interactions between theophylline and other medication (Part II).
Topics: Aged; Calcium Channel Blockers; Child; Drug Interactions; Female; Humans; Interferons; Male; Pregnan | 1991 |
[Problems of respiratory drug therapy in pregnancy].
Topics: Adrenal Cortex Hormones; Aminophylline; Anti-Bacterial Agents; Antitubercular Agents; Asthma; Cromol | 1989 |
Oral contraceptive drug interactions.
Topics: Acetaminophen; Anti-Anxiety Agents; Anti-Bacterial Agents; Benzodiazepines; Contraceptives, Oral; Dr | 1985 |
Pharmacologic effects on labor: effects of drugs on dystocia, labor, and uterine activity.
Topics: Adrenergic beta-Agonists; Aminophylline; Anesthetics; Animals; Anti-Inflammatory Agents, Non-Steroid | 1987 |
[Pregnancy and asthma].
Topics: Adrenergic beta-Antagonists; Asthma; Bronchodilator Agents; Female; Fetus; Hematopoiesis; Hormones; | 1988 |
Insulin and glucagon during the perinatal period: secretion and metabolic effects on the liver.
Topics: Animals; Animals, Newborn; Blood Glucose; Diabetes Mellitus, Experimental; Fasting; Female; Fetal Bl | 1985 |
Current concepts. Management of asthma during pregnancy.
Topics: Adrenal Cortex Hormones; Asthma; Birth Weight; Epinephrine; Female; Fetal Death; Fetus; Hormones; Hu | 1985 |
Gonadotropin action on cultured Graafian follicles: induction of maturation division of the mammalian oocyte and differentiation of the luteal cell.
Topics: Adenylyl Cyclases; Animals; Cell Differentiation; Cells, Cultured; Chorionic Gonadotropin; Chromosom | 1974 |
8 trials available for theophylline and Pregnancy
| Article | Year |
|---|---|
A non-interventional comparative study of the 20:1 combination of cafedrine/theodrenaline versus ephedrine for the treatment of intra-operative arterial hypotension: the 'HYPOTENS' study design and rationale.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Cohort Studies | 2018 |
Blood pressure and endothelial function in healthy, pregnant women after acute and daily consumption of flavanol-rich chocolate: a pilot, randomized controlled trial.
Topics: Adolescent; Adult; Biomarkers; Blood Pressure; Cacao; Caffeine; Candy; Catechin; Double-Blind Method | 2013 |
Pregnancy-induced changes in the pharmacokinetics of caffeine and its metabolites.
Topics: Adult; Caffeine; Cytochrome P-450 CYP1A2; Female; Humans; Pregnancy; Pregnancy Trimesters; Theobromi | 2016 |
The effect of active and passive household cigarette smoke exposure on pregnant women with asthma.
Topics: Administration, Inhalation; Administration, Oral; Adult; Asthma; Beclomethasone; Disease Progression | 2010 |
Randomized trial of inhaled beclomethasone dipropionate versus theophylline for moderate asthma during pregnancy.
Topics: Administration, Inhalation; Adult; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronchodilator Age | 2004 |
[Human placental lactogen (HPL) levels in the maternal serum following long-term intake of xantinol nicotinate (Complamin Retard) (author's transl)].
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Placental Insufficiency; Placental La | 1980 |
Relation between adenosine and T-helper 1/T-helper 2 imbalance in women with preeclampsia.
Topics: Adenosine; Adult; CD4-Positive T-Lymphocytes; Female; Humans; In Vitro Techniques; Interferon-gamma; | 2002 |
[Effect of Complamin on the fetoplacental functional status during labor in normal pregnancies and in gestosis].
Topics: Apgar Score; Clinical Trials as Topic; Female; Fetus; Humans; Labor, Obstetric; Nicotinic Acids; Pla | 1974 |
332 other studies available for theophylline and Pregnancy
| Article | Year |
|---|---|
Maternal caffeine intake and DNA methylation in newborn cord blood.
Topics: Adult; Caffeine; DNA Methylation; Epigenesis, Genetic; Female; Fetal Blood; Gestational Age; Humans; | 2022 |
Use of dimethylxanthine theophylline (SpermMobil
Topics: Adult; Female; Fertilization in Vitro; Humans; Male; Pregnancy; Pregnancy Outcome; Retrospective Stu | 2019 |
Treatment of spinal anaesthesia-induced hypotension with cafedrine/theodrenaline versus ephedrine during caesarean section: Results from HYPOTENS, a national, multicentre, prospective, noninterventional study.
Topics: Adolescent; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Ephedrine; Female; | 2021 |
Association Between Maternal Caffeine Consumption and Metabolism and Neonatal Anthropometry: A Secondary Analysis of the NICHD Fetal Growth Studies-Singletons.
Topics: Adult; Anthropometry; Biomarkers; Birth Weight; Caffeine; Female; Fetal Development; Follow-Up Studi | 2021 |
Placentation-related processes in a human first-trimester extravillous trophoblast cell line (HTR-8/SVneo cells) are affected by several xenobiotics.
Topics: Apoptosis; Cell Culture Techniques; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Fem | 2019 |
[Antihypotensive drugs in cesarean sections : Treatment of arterial hypotension with ephedrine, phenylephrine and Akrinor® (cafedrine/theodrenaline) during cesarean sections with spinal anesthesia].
Topics: Adolescent; Adult; Anesthesia, Obstetrical; Cesarean Section; Drug Combinations; Ephedrine; Female; | 2019 |
Granisetron reduces the need for uterotonics but not sympathomimetics during cesarean delivery.
Topics: Adult; Anesthesia, Spinal; Antiemetics; Case-Control Studies; Cesarean Section; Drug Combinations; F | 2019 |
Rotational culture and integration with amniotic stem cells reduce porcine islet immunoreactivity in vitro and slow xeno-rejection in a murine model of islet transplantation.
Topics: Adult; Amnion; Animals; Arginine; CD4-Positive T-Lymphocytes; Cell Culture Techniques; Coculture Tec | 2019 |
Healthy live birth using theophylline in a case of retrograde ejaculation and absolute asthenozoospermia.
Topics: Adult; Asthenozoospermia; Ejaculation; Female; Humans; Infant, Newborn; Live Birth; Male; Pregnancy; | 2014 |
Trans-generational effects of early life stress: the role of maternal behavior.
Topics: Animals; Animals, Newborn; Behavior, Animal; Chromatin Immunoprecipitation; Cognition; Emotions; Fem | 2014 |
Theophylline improves lipopolysaccharide-induced alveolarization arrest through inflammatory regulation.
Topics: Animals; Animals, Newborn; Bronchodilator Agents; Bronchopulmonary Dysplasia; Chemokine CCL3; Chemok | 2014 |
Comparison of maternal and fetal blood levels of caffeine and its metabolite. A pilot study.
Topics: Adult; Caffeine; Female; Fetal Blood; Humans; Infant, Newborn; Logistic Models; Male; Pilot Projects | 2014 |
Maternal serum paraxanthine during pregnancy and offspring body mass index at ages 4 and 7 years.
Topics: Adult; Biomarkers; Body Mass Index; Caffeine; Case-Control Studies; Child; Child, Preschool; Female; | 2015 |
Theophylline Pharmacokinetics in Foetal Sheep: Maternal Metabolic Capacity is the Principal Driver.
Topics: Animals; Area Under Curve; Female; Fetal Blood; Fetus; Half-Life; Injections, Intravenous; Maternal- | 2015 |
Healthy twin live-birth after ionophore treatment in a case of theophylline-resistant Kartagener syndrome.
Topics: Adult; Calcium Ionophores; Female; Humans; Infertility, Male; Kartagener Syndrome; Live Birth; Male; | 2015 |
Second-Trimester Maternal Serum Paraxanthine, CYP1A2 Activity, and the Risk of Severe Preeclampsia.
Topics: Adult; Caffeine; Case-Control Studies; Cytochrome P-450 CYP1A2; Female; Humans; Pre-Eclampsia; Pregn | 2015 |
Effects of d- and l-limonene on the pregnant rat myometrium in vitro.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cyclic AMP; Cyclohexenes; Female; Indoles; Limo | 2015 |
Maternal Caffeine Intake During Pregnancy and Child Cognition and Behavior at 4 and 7 Years of Age.
Topics: Adult; Caffeine; Child; Child Behavior; Child, Preschool; Coffee; Cognition; Female; Follow-Up Studi | 2015 |
Should neonates with perinatal asphyxia receive a single dose of IV theophylline to prevent acute kidney injury?
Topics: Acute Kidney Injury; Asphyxia; Asphyxia Neonatorum; Female; Humans; Infant, Newborn; Pregnancy; Theo | 2016 |
Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model II: Verification of the model for passive placental permeability drugs.
Topics: Female; Fetus; Humans; Kinetics; Maternal-Fetal Exchange; Midazolam; Models, Biological; Permeabilit | 2017 |
Medications as a potential source of exposure to phthalates in the U.S. population.
Topics: Adolescent; Adult; Data Collection; Didanosine; Environmental Exposure; Female; Humans; Male; Mesala | 2009 |
[Pulmonary diseases in pregnancy. What drugs are permitted?].
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antitubercular Agents; | 2009 |
Effects of maternal hypoxia on muscle vasodilatation evoked by acute systemic hypoxia in adult rat offspring: changed roles of adenosine and A1 receptors.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Bradycardia; Endothelium, Vascular; Female; H | 2010 |
Regulation of sFlt-1 and VEGF secretion by adenosine under hypoxic conditions in rat placental villous explants.
Topics: Adenosine; Animals; Chorionic Villi; Enzyme-Linked Immunosorbent Assay; Female; Hypoxia; Placenta; P | 2010 |
Improving the relaxing effect of terbutaline with phosphodiesterase inhibitors: studies on pregnant rat uteri in vitro.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Cyclic AMP; Drug Synergism; Female; Lipopolysaccharide | 2010 |
Impact of cafedrine/theodrenaline (Akrinor® ) on therapy of maternal hypotension during spinal anesthesia for Cesarean delivery: a retrospective study.
Topics: Adult; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Drug Combinations; Elective Surgical Pr | 2010 |
Caffeine and insulin resistance in pregnancy.
Topics: Birth Weight; Caffeine; Female; Homeostasis; Humans; Infant, Newborn; Insulin Resistance; Male; Preg | 2011 |
Pharmacological stimulation of sperm motility in frozen and thawed testicular sperm using the dimethylxanthine theophylline.
Topics: Algorithms; Cells, Cultured; Embryo Transfer; Female; Fertilization in Vitro; Freezing; Humans; Infe | 2011 |
Delayed subdural haematoma complicated by abducens nerve palsy and cortical vein thrombosis after obstetric epidural anaesthesia.
Topics: Abducens Nerve; Abducens Nerve Diseases; Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthesia, | 2012 |
Successful treatment of life threatening theophylline intoxication in a pregnant patient by hemodialysis.
Topics: Abortion, Induced; Adult; Drug Overdose; Female; Humans; Pregnancy; Pregnancy Complications; Renal D | 2013 |
Uterus-relaxing effect of β2-agonists in combination with phosphodiesterase inhibitors: studies on pregnant rat in vivo and on pregnant human myometrium in vitro.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type | 2013 |
A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women.
Topics: Clonidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Dextromethorpha | 2013 |
Adenosine A1 receptor down-regulation in mothers and fetal brain after caffeine and theophylline treatments to pregnant rats.
Topics: Animals; Binding, Competitive; Brain; Caffeine; Down-Regulation; Female; Gestational Age; Pregnancy; | 2002 |
The role of adenosine in regulation of cerebral blood flow during hypoxia in the near-term fetal sheep.
Topics: Adenosine; Animals; Blood Glucose; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Fema | 2002 |
[Treatment of bronchial asthma in pregnancy].
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Anti-Inflammatory Agents; Asthma; Female; Huma | 2003 |
[Reactivity of the placental barrier].
Topics: Bile Acids and Salts; Female; Glycerol; Histamine; Histamine Agents; Humans; Placenta; Pregnancy; Sa | 1955 |
Toxemia of pregnancy: a new treatment for controlling edema.
Topics: Edema; Female; Histamine H1 Antagonists; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Complications; | 1957 |
Evaluation of a diuretic substance in the management of mild pre-eclampsia; a report of 47 clinical trials.
Topics: Disease Management; Diuretics; Eclampsia; Female; Humans; Pre-Eclampsia; Pregnancy; Theophylline | 1958 |
[CLINICAL EVALUATION OF THE USE OF A DRUG WITH FIBRINOLYTIC ACTION IN THE THERAPY OF GESTOSIS IN THE THIRD TRIMESTER].
Topics: Antihypertensive Agents; Diuretics; Drug Therapy; Female; Humans; Niacin; Nicotinic Acids; Papaverin | 1964 |
[ON THE PRENATAL TOXICITY OF DIPHENYLPYRALINE 8-CHLOROTHEOPHYLLINATE WITH REFERENCE TO EXPERIENCES WITH THALIDOMIDE AND CAFFEINE].
Topics: Abnormalities, Drug-Induced; Anti-Allergic Agents; Caffeine; Fetal Death; Histamine H1 Antagonists; | 1964 |
[POSSIBILITIES AND ADVANTAGES OF FIBRINOLYTIC DRUGS IN THERAPY OF KIDNEY DISEASE IN PREGNANCY].
Topics: Blood Coagulation Disorders; Drug Therapy; Female; Fibrinolysis; Fibrinolytic Agents; Humans; Kidney | 1964 |
[INTRAVASCULAR COAGULATION AND FIBRINOLYSIS. EXPERIMENTAL CONTRIBUTION TO THE STUDY OF TREATMENT OF KIDNEY DISEASE IN PREGNANCY].
Topics: Animals; Blood Coagulation; Blood Coagulation Disorders; Female; Fibrinolysis; Humans; Kidney; Kidne | 1964 |
Asthma symptoms, severity, and drug therapy: a prospective study of effects on 2205 pregnancies.
Topics: Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Birth Weight; Case-Control Studies; | 2003 |
Regarding "An unexpected distribution of sodium concentration in serum specimens stored for more than 30 years".
Topics: Abortion, Spontaneous; Adult; Bias; Caffeine; Female; Humans; Pregnancy; Risk Factors; Sodium; Speci | 2004 |
Tumor necrosis factor-alpha in whole blood cultures of preeclamptic patients and healthy pregnant and nonpregnant women.
Topics: Adult; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Humans; Leukocyte Count; Le | 2004 |
Chronic caffeine or theophylline intake during pregnancy inhibits A1 receptor function in the rat brain.
Topics: Adenosine A1 Receptor Antagonists; Adenylyl Cyclases; Animals; Brain; Caffeine; Female; Pregnancy; P | 2005 |
Anesthetic management of a patient with histiocytosis X and pulmonary complications during Caesarean section.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anti-Asthmatic Agents; Betamethasone; Blood Ga | 2004 |
Effect of chronic gestational treatment with caffeine or theophylline on Group I metabotropic glutamate receptors in maternal and fetal brain.
Topics: Animals; Blotting, Western; Brain; Caffeine; Cell Membrane; Dose-Response Relationship, Drug; Drug I | 2005 |
In vitro fertilization and subsequent development of porcine oocytes using cryopreserved and liquid-stored spermatozoa from various boars.
Topics: Adenosine; Animals; Blastocyst; Culture Media; Cysteine; Female; Fertilization in Vitro; Male; Oocyt | 2005 |
Caffeine metabolites in umbilical cord blood, cytochrome P-450 1A2 activity, and intrauterine growth restriction.
Topics: Adult; Biomarkers; Caffeine; Chi-Square Distribution; Connecticut; Cytochrome P-450 Enzyme System; F | 2006 |
Characteristics of thiamine uptake by the BeWo human trophoblast cell line.
Topics: Biological Transport; Caffeine; Cell Line, Tumor; Cell Membrane Structures; Ethanol; Female; Flavono | 2006 |
Release of non-neuronal acetylcholine from the isolated human placenta is affected by antidepressants.
Topics: Acetylcholine; Amitriptyline; Antidepressive Agents; Dose-Response Relationship, Drug; Doxepin; Fema | 2007 |
Caffeine intake and small-for-gestational-age birth: modifying effects of xenobiotic-metabolising genes and smoking.
Topics: Caffeine; Case-Control Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Female; Humans; In | 2007 |
Perinatal dioxin exposure, cytochrome P-450 activity, liver functions and thyroid hormones at follow-up after 7-12 years.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Caffeine; Child; Cytochrome P-450 CYP1A2; Dioxins | 2008 |
Long-term asthma therapy: adapt steroid therapy to severity.
Topics: Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Asthma; Beclomethasone; | 2007 |
Assessing caffeine exposure in pregnant women.
Topics: Adult; Biomarkers; Caffeine; Diet Records; Feeding Behavior; Female; Humans; Pregnancy; Pregnancy Ou | 2008 |
Inducibility of carbamoylphosphate synthetase (ammonia) in cultures of embryonic hepatocytes: ontogenesis of the responsiveness to hormones.
Topics: Animals; Bucladesine; Carbamoyl-Phosphate Synthase (Ammonia); Cells, Cultured; Dexamethasone; Enzyme | 1984 |
Asthma in pregnancy: current concepts.
Topics: Acute Disease; Adolescent; Adrenergic beta-Agonists; Adult; Asthma; Beclomethasone; Cromolyn Sodium; | 1980 |
Islet secretion in a new experimental model for non-insulin-dependent diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Glucagon; Glucos | 1981 |
Effects of methylxanthines on lipid synthesis in developing neural systems.
Topics: Acetyl-CoA Carboxylase; Aging; Aminophylline; Brain; Caffeine; Cell Division; Cell Line; Cholesterol | 1981 |
[Treatment of the asthmatic crisis].
Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Asthma; Female; Humans; Male; Pregnancy; Theop | 1982 |
[Risk evaluation and management of the pregnant asthmatic].
Topics: Adrenergic beta-Agonists; Asthma; Cromolyn Sodium; Female; Humans; Hydrocortisone; Ketotifen; Pregna | 1982 |
Managing asthma during pregnancy.
Topics: Adrenergic beta-Agonists; Anti-Bacterial Agents; Asthma; Female; Glucocorticoids; Hemodynamics; Huma | 1984 |
Facilitation of progesterone induced lordosis behavior by phosphodiesterase inhibitors in estrogen primed rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Drug Synergism; Estradiol; Estrogens; Estrus; Female; Phosphod | 1981 |
Effect of 3-isobutyl-1-methylxanthine on prolactin actions on RNA synthesis, casein synthesis, lipid synthesis and ornithine decarboxylase activity in mouse mammary gland explants.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carboxy-Lyases; Caseins; Dose-Response Relationship, Drug; Fem | 1982 |
Stimulation of palatal glycosaminoglycan synthesis by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cells, Cu | 1982 |
Inhibition of prostacyclin synthesis in endothelial cells by methylisobutylxanthine is not mediated through elevated cAMP level.
Topics: 1-Methyl-3-isobutylxanthine; 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arachidonic Acid; Arachid | 1983 |
Effects of 3-isobutyl-1-methylxanthine on secretory response, cAMP accumulation and DNA synthesis of islets from postnatal and adult Wistar rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; DNA; Female; Glucose; Insulin; Insulin Secretion; | 1982 |
Modulation of cell proliferation in cultured postimplantation embryos by cyclic AMP.
Topics: Animals; Blastocyst; Cell Division; Cyclic AMP; Embryo Implantation; Female; Mice; Pregnancy; Theoph | 1980 |
Testosterone synthesis in rhesus fetal testes: comparison between middle and late gestation.
Topics: Animals; Chorionic Gonadotropin; Cyclic AMP; Female; Fetal Blood; Gestational Age; Haplorhini; In Vi | 1980 |
Enhanced excitability of the uterus of the pregnant rabbit by imidazole stimulation of cyclic AMP phosphodiesterase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Female; Imidazoles; In Vitro Techniques; Isoproterenol | 1980 |
Lactose synthesis and the utilisation of glucose by rat mammary acini.
Topics: Animals; Bucladesine; Cyclic AMP; Female; Glucose; Intracellular Fluid; Lactation; Lactose; Mammary | 1981 |
Macromolecular synthesis is required for stimulation of estrogen synthetase activity by dibutyryl cyclic AMP plus theophylline in choriocarcinoma cell culture.
Topics: Aromatase; Bucladesine; Cells, Cultured; Choriocarcinoma; Cycloheximide; Dactinomycin; Estrogens; Fe | 1981 |
The ontogeny of the thyrotropin-thyroid axis in early bovine embryos.
Topics: Adenosine; Animals; Bucladesine; Cattle; Dinoprostone; Embryo, Mammalian; Female; Gestational Age; I | 1981 |
Immunologic and biologic characteristics of human decidual prolactin.
Topics: Bucladesine; Cycloheximide; Decidua; Estradiol; Female; Guanosine Triphosphate; Humans; Pregnancy; P | 1982 |
Temporal aspects of the N- and O-glycosylation of human chorionic gonadotropin.
Topics: Acetylglucosamine; Bucladesine; Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Female; Glycosid | 1982 |
Estrogen synthetase stimulation by dibutyryl cyclic adenosine 3',5'-monophosphate in human choriocarcinoma cell culture: the relative biosynthetic rate of the nicotinamide adenine dinucleotide phosphate (reduced form)-cytochrome c reductase component.
Topics: Aromatase; Bucladesine; Cell Line; Choriocarcinoma; Enzyme Induction; Female; Humans; Immunosorbent | 1982 |
Effects of prostaglandins on cyclic nucleotide phosphodiesterase activity in the human term placenta.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alprostadil; Cyclic AMP; Cyclic GMP; Dose-Response Relationship | 1982 |
Specific binding sites for epidermal growth factor and its effect on human chorionic gonadotrophin secretion by cultured tumour cell lines: comparison between trophoblastic and non-trophoblastic cells.
Topics: Bucladesine; Cell Line; Chorionic Gonadotropin; Epidermal Growth Factor; ErbB Receptors; Female; HeL | 1982 |
Pharmacologically induced changes in human beta-chorionic gonadotropin (beta-hCG) synthesis by human placenta in organ culture.
Topics: Bucladesine; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Ethanolamines; Female; Fenote | 1982 |
In vitro study of phosphodiesterase-inhibiting drugs: a complement to beta-sympathomimetic drug therapy in premature labor?
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Drug Interactions; Female; Humans; Muscle Relaxation; My | 1983 |
In vitro and in vivo displacement of [3H]-diazepam binding by purine derivatives in developing rat brain.
Topics: Animals; Binding, Competitive; Brain; Caffeine; Diazepam; Female; In Vitro Techniques; Kinetics; Mal | 1984 |
Theophylline metabolism: variation and genetics.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Immunoenzyme Tec | 1984 |
Regulation of peripheral lipogenesis by glucagon. Inability of the hormone to inhibit lipogenesis in rat mammary acini in vitro in the presence or absence of agents which alter its effects on adipocytes.
Topics: Adenosine Deaminase; Adipose Tissue; Animals; Dose-Response Relationship, Drug; Fatty Acids; Female; | 1984 |
Potentiating effects of methylxanthines on teratogenicity of mitomycin C in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Caffeine; Drug Synergism; Female; | 1983 |
Successful pregnancy in beta-thalassaemia major.
Topics: Adult; Blood Transfusion; Deferoxamine; Female; Glucose; Humans; Hypoglycemia; Infant, Newborn; Infa | 1983 |
Iodide containing theophylline products.
Topics: Acne Vulgaris; Adolescent; Asthma; Drug Combinations; Female; Goiter; Humans; Infant, Newborn; Iodid | 1980 |
Theophylline metabolism in preterm neonates during the first weeks of life.
Topics: Betamethasone; Female; Half-Life; Humans; Infant, Newborn; Infant, Premature; Kidney; Liver; Materna | 1984 |
A physiologically based pharmacokinetic model for theophylline disposition in the pregnant and nonpregnant rat.
Topics: Animals; Female; Fetus; Kinetics; Lung; Maternal-Fetal Exchange; Models, Biological; Pregnancy; Preg | 1984 |
Caffeine and its dimethylxanthines and fetal cerebral development in rat.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Caffeine; Female; Fetus; Maternal-Fetal Exchange; Pregn | 1984 |
[Effect of theophylline on brain development in the perinatal period].
Topics: Animals; Brain; Brain Chemistry; Female; Organ Size; Pregnancy; Rabbits; Theophylline | 1984 |
Placental transfer model in the pregnant ewe: use of stable isotopes.
Topics: Animals; Female; Fetus; Kinetics; Maternal-Fetal Exchange; Models, Biological; Placenta; Pregnancy; | 1984 |
Caffeine, theophylline and theobromine in pregnancy.
Topics: Caffeine; Female; Humans; Pregnancy; Theobromine; Theophylline | 1984 |
Improved micro-method for the high-performance liquid chromatographic determination of caffeine and paraxanthine in biological fluids.
Topics: Animals; Body Fluids; Caffeine; Chromatography, High Pressure Liquid; Female; Fetal Blood; Pregnancy | 1984 |
Effect of theophylline F2-alpha-induced contractile activity of the uterus.
Topics: Abortion, Induced; Adolescent; Adult; Dinoprost; Female; Humans; Infusions, Parenteral; Pregnancy; P | 1984 |
Antagonism of the 5-HT-induced bronchoconstriction in the cat.
Topics: Animals; Bronchi; Carbachol; Cats; Clenbuterol; Cyproheptadine; Female; Hemodynamics; Ketanserin; Ma | 1983 |
Pharmacokinetics of intravenous theophylline in pregnant patients at term.
Topics: Adolescent; Adult; Female; Half-Life; Humans; Infusions, Parenteral; Kinetics; Labor, Obstetric; Mat | 1983 |
Di-allelic alloantigenic systems on subsets of T cells.
Topics: Alleles; Drug Resistance; Female; HLA Antigens; Humans; Immunoglobulin gamma-Chains; Immunoglobulin | 1982 |
[Pharmacokinetics of drugs from the breast-feeding mother passing into the body of the infant, using theophylline as an example].
Topics: Breast Feeding; Female; Humans; Infant, Newborn; Kinetics; Maternal-Fetal Exchange; Milk, Human; Pre | 1983 |
Theobromine metabolism and pharmacokinetics in pregnant and nonpregnant Sprague-Dawley rats.
Topics: Animals; Female; Kinetics; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Theobromine; Th | 1983 |
Human fetal pancreas: culture and function in vitro.
Topics: C-Peptide; Female; Fetus; Glucagon; Glucose; Histocytochemistry; Humans; Insulin; Insulin Secretion; | 1980 |
Development of insulin release by fetal rat pancreas in vitro: effects of glucose, amino acids, and theophylline.
Topics: Amino Acids; Animals; Dose-Response Relationship, Drug; Female; Fetus; Gestational Age; Glucose; Ins | 1980 |
Determination of human serum placental alkaline phosphatase, using theophylline inhibition.
Topics: Alkaline Phosphatase; Bone and Bones; Female; Fetal Death; Humans; Intestinal Mucosa; Isoenzymes; Ki | 1982 |
Apnea associated with theophylline withdrawal in a term neonate.
Topics: Apnea; Caffeine; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange | 1982 |
Placental theophylline transfer in pregnant asthmatics.
Topics: Adolescent; Adult; Asthma; Caffeine; Female; Fetal Blood; Fetus; Half-Life; Heart; Hemodynamics; Hum | 1982 |
Metabolism and distribution of labeled theophylline in the pregnant rat. Impairment of theophylline metabolism by pregnancy and absence of a blood-brain barrier in the fetus.
Topics: Animals; Blood-Brain Barrier; Brain Chemistry; Caffeine; Female; Fetus; Maternal-Fetal Exchange; Pre | 1982 |
Theophylline elimination in the pregnant and fetal rabbit.
Topics: Aminophylline; Animals; Animals, Newborn; Female; Fetal Blood; Half-Life; Infusions, Parenteral; Mal | 1982 |
Increased theophylline metabolism in premature infants after prenatal betamethasone administration.
Topics: Aging; Betamethasone; Birth Weight; Dealkylation; Female; Gestational Age; Half-Life; Humans; Infant | 1982 |
Episodic complete airway obstruction in infants.
Topics: Airway Obstruction; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Infant, Newb | 1981 |
Conversion of theophylline to caffeine by the human fetus.
Topics: Amniotic Fluid; Caffeine; Female; Fetal Blood; Fetus; Humans; Infant, Newborn; Infant, Premature; Ma | 1981 |
Excretion of methylxanthines in human milk.
Topics: Adult; Beverages; Caffeine; Child, Preschool; Chromatography, High Pressure Liquid; Female; Humans; | 1981 |
Dyphylline elimination kinetics in lactating women: blood to milk transfer.
Topics: Adult; Biotransformation; Dyphylline; Female; Half-Life; Humans; Kinetics; Lactation; Milk, Human; P | 1981 |
Theophylline therapy during pregnancy.
Topics: Asthma; Female; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications; Theophylline | 1980 |
[Circulatory effects of xanthinol nicotinate in advanced pregnancy (author's transl)].
Topics: Adult; Blood Circulation; Blood Volume; Drug Evaluation; Female; Hemodynamics; Humans; Placenta Dise | 1980 |
Slow-release theophylline in pregnant asthmatics.
Topics: Adolescent; Adult; Asthma; Case-Control Studies; Delayed-Action Preparations; Female; Humans; Pregna | 1995 |
The human myometrial CRH receptor: G proteins and second messengers.
Topics: Adenosine Triphosphate; Arachidonic Acid; Cell Membrane; Corticotropin-Releasing Hormone; Cyclic AMP | 1994 |
Accumulation of theophylline, theobromine and paraxanthine in the fetal rat brain following a single oral dose of caffeine.
Topics: Animals; Biotransformation; Brain; Caffeine; Chromatography, High Pressure Liquid; Female; Pregnancy | 1993 |
[Severe theophylline toxicity in a pregnant asthmatic patient].
Topics: Adult; Asthma; Cesarean Section; Female; Humans; Poisoning; Pregnancy; Pregnancy Complications; Theo | 1993 |
Successful cryopreservation of fetal porcine proislets.
Topics: Animals; Blood Glucose; Cells, Cultured; Cryopreservation; Diabetes Mellitus, Experimental; Female; | 1993 |
Influence of prolonged adenosine receptor blockade on fetal sleep and breathing patterns.
Topics: Animals; Apnea; Female; Fetus; Infusions, Intravenous; Phenylisopropyladenosine; Pregnancy; Purinerg | 1993 |
Role of adenosine triphosphate and adenosine in oxygen-induced pulmonary vasodilation in fetal lambs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Female; Fetus; Oxygen; Pregnancy; Pulmonary Circulation; | 1993 |
[Asthma and pregnancy].
Topics: Adrenal Cortex Hormones; Asthma; Bronchodilator Agents; Female; Humans; Peak Expiratory Flow Rate; P | 1995 |
Adenosine mediates metabolic and cardiovascular responses to hypoxia in fetal sheep.
Topics: Acidosis; Adenosine; Animals; Blood Pressure; Female; Fetus; Glycolysis; Heart Rate; Hypoxia; Pregna | 1995 |
Kinetics of theophylline in apnea of prematurity in small for gestational age babies.
Topics: Aminophylline; Bronchodilator Agents; Case-Control Studies; Dose-Response Relationship, Drug; Drug A | 1996 |
Study of post-natal effect of chemopreventive agents on ethylnitrosourea-induced transplacental carcinogenesis in rats. III. Inhibitory action of indomethacin, voltaren, theophylline and epsilon-aminocaproic acid.
Topics: Aminocaproic Acid; Animals; Anticarcinogenic Agents; Brain Neoplasms; Carcinogens; Central Nervous S | 1996 |
Maternal theophylline administration and breathing movements in late-gestation human fetuses.
Topics: Adult; Blood Glucose; Female; Fetal Movement; Gestational Age; Humans; Pregnancy; Respiration; Theop | 1996 |
Suppressive action of endogenous adenosine on ovine fetal nonshivering thermogenesis.
Topics: Adenosine; Animals; Body Temperature; Female; Glycerol; Pregnancy; Sheep; Theophylline | 1996 |
Reproductive toxicology. Theophylline.
Topics: Alopecia; Animals; Birth Weight; Body Weight; Epididymis; Female; Fertility; Litter Size; Liver; Mal | 1997 |
Purine nucleotides contribute to pulmonary vasodilation caused by birth-related stimuli in the ovine fetus.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Gas Analysis; Erythrocytes; Female; Hydrogen-Ion C | 1997 |
Effects of prenatal androgenization and lactation on adipose tissue metabolism in finishing single-calf heifers.
Topics: Acetates; Adenosine Deaminase; Adipose Tissue; Animals; Biopsy; Carbon Radioisotopes; Cattle; Diet; | 1997 |
Plasma protein binding of theophylline in late pregnancy in rat.
Topics: Animals; Blood Proteins; Bronchodilator Agents; Female; Gestational Age; Pregnancy; Rats; Rats, Spra | 1997 |
Serum caffeine and paraxanthine as markers for reported caffeine intake in pregnancy.
Topics: Biomarkers; Blood Specimen Collection; Caffeine; Cohort Studies; Diet; Female; Humans; Mental Recall | 1998 |
Drugs for asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adr | 1999 |
Adenosine modulates corticotropin and cortisol release during hypoxia in fetal sheep.
Topics: Adenosine; Adrenocorticotropic Hormone; Animals; Blood Pressure; Bradycardia; Female; Fetal Blood; F | 1999 |
Role of adenosine in regulation of brain temperature in fetal sheep.
Topics: Adenosine; Animals; Body Temperature Regulation; Brain; Constriction; Female; Fetal Hypoxia; Fetus; | 1999 |
The adenosine A(1)-receptor antagonist 8-CPT reverses ethanol-induced inhibition of fetal breathing movements.
Topics: Animals; Blood Glucose; Blood Pressure; Electrocardiography; Ethanol; Eye Movements; Female; Fetal B | 1999 |
Maternal serum paraxanthine, a caffeine metabolite, and the risk of spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Caffeine; Case-Control Studies; Female; Humans; Odds Ratio; Pregnancy; | 1999 |
Caffeine--filtering the facts.
Topics: Abortion, Spontaneous; Breast Feeding; Caffeine; Child Development; Female; Fetus; Humans; Infant; P | 1999 |
Disposable optical sensor chip for medical diagnostics: new ways in bioanalysis.
Topics: Biosensing Techniques; Chorionic Gonadotropin; Diagnostic Techniques and Procedures; Female; Humans; | 1999 |
Otocephaly: prenatal diagnosis of a new case and etiopathogenetic considerations.
Topics: Abnormalities, Multiple; Albuterol; Anti-Asthmatic Agents; Beclomethasone; Craniofacial Abnormalitie | 2000 |
Caffeine consumption and the risk of spontaneous abortions.
Topics: Abortion, Spontaneous; Caffeine; Case-Control Studies; Female; Humans; Pregnancy; Reproducibility of | 2000 |
Drugs for asthma.
Topics: Acetates; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta | 2000 |
Association of sympathomimetic drugs with malformations.
Topics: Adult; Aerosols; Animals; Asthma; Drug Combinations; Ephedrine; Female; Humans; Hypnotics and Sedati | 2000 |
Teratogenic and fetal toxicity following intravenous theophylline administration in pregnant rabbits is related to maternal drug plasma levels.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Bone and Bones; Dose-Response Relationship, Drug; | 2000 |
Purinergic contribution to circulatory, metabolic, and adrenergic responses to acute hypoxemia in fetal sheep.
Topics: Animals; Blood Glucose; Blood Pressure; Catecholamines; Epinephrine; Female; Femoral Artery; Fetal B | 2001 |
Plasma adenosine levels and P-selectin expression on platelets in preeclampsia.
Topics: Adenosine; Adult; Case-Control Studies; Female; Humans; P-Selectin; Platelet Activation; Pre-Eclamps | 2001 |
Maternal serum caffeine metabolites and small-for-gestational age birth.
Topics: Adult; Analysis of Variance; Caffeine; Chi-Square Distribution; Female; Humans; Infant, Newborn; Inf | 2002 |
Effects of caffeine and its reactive metabolites theophylline and theobromine on the differentiating testis.
Topics: Animals; Caffeine; Cell Differentiation; Female; Gestational Age; Leydig Cells; Male; Maternal-Fetal | 2001 |
Acute asthma in adults.
Topics: Acute Disease; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Age Factors; Airway Resista | 1979 |
The inability of dibutyryl adenosine 3',5'-monophosphate to induce the decidual reaction in intact pseudopregnant mice.
Topics: Animals; Bucladesine; Decidua; Dose-Response Relationship, Drug; Female; Histamine; Injections; Inje | 1975 |
Regulation of human chorionic gonadotropin (hCG) secretion by serum and dibutyryl cyclic AMP in malignant trophoblast cells in vitro.
Topics: Animals; Blood; Bucladesine; Cattle; Cell Line; Chorionic Gonadotropin; Dactinomycin; Female; Humans | 1975 |
Adrenocorticotrophin and the development of insulin secretion in the rabbit foetus.
Topics: Adrenocorticotropic Hormone; Animals; Female; Gestational Age; Glucagon; Glucose; Hydrocortisone; In | 1975 |
Inhibition by cyclic AMP of lactose production in lactating guinea pig mammary gland slices.
Topics: Animals; Bucladesine; Colchicine; Cyclic AMP; Cytochalasin B; Dose-Response Relationship, Drug; Epin | 1975 |
Human placental cAMP phosphodiesterase activity kinetic properties and sensitivity to some drugs and hormones.
Topics: Caffeine; Cyclic AMP; Epinephrine; Estradiol; Female; Flufenamic Acid; Hormones; Humans; Imidazoles; | 1975 |
Effect of lithium ions on RNA synthesis in mammary gland explants of mice.
Topics: Animals; Culture Techniques; Cyclic GMP; Female; Hydrocortisone; Insulin; Ions; Lithium; Mammary Gla | 1975 |
Hormonal regulation of incorporation of alanine-U-14C into glucose in human fetal liver explants. Effect of dibutyryl cyclic AMP, glucagon, insulin, and triamcinolone.
Topics: Alanine; Bucladesine; Drug Synergism; Female; Fetus; Glucagon; Gluconeogenesis; Humans; Insulin; Kin | 1975 |
Effects of arachidonic acid on RNA metabolism in mammary gland explants of mice.
Topics: Animals; Arachidonic Acids; Breast; Bucladesine; Cyclic GMP; Female; Indomethacin; Linoleic Acids; M | 1975 |
Hormonal regulation of glycogen metabolism in human fetal liver. I. Normal development and effects of dibutyryl cyclic AMP, glucagon, and insulin in liver explants.
Topics: Bucladesine; Culture Techniques; Cyclic AMP; Drug Synergism; Female; Gestational Age; Glucagon; Glyc | 1975 |
Modification of myometrial activity in vivo by administration of cyclic nucleotides and theophylline to the pregnant rat.
Topics: Animals; Bucladesine; Cyclic AMP; Female; Oxytocin; Pregnancy; Pregnancy, Animal; Prostaglandins F; | 1975 |
Early stimulation of human chorionic gonadotropin secretion by dibutyryl cyclic AMP and theophylline in human malignant trophoblast cells in vitro: inhibition by actinomycin D, alpha-amanitin, and cordycepin.
Topics: Amanitins; Bucladesine; Cell Line; Cells, Cultured; Chorionic Gonadotropin; Dactinomycin; Deoxyadeno | 1975 |
Cyclic AMP phosphodiesterase activity in fetal and adult muscle of the rhesus monkey.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffei | 1976 |
Prostaglandin biosynthesis and stimulation of cyclic AMP in primary monolayer cultures of epithelial cells from mouse mammary gland.
Topics: Animals; Collagen; Cyclic AMP; Drug Interactions; Female; Mammary Glands, Animal; Mice; Mice, Inbred | 1976 |
Theophylline induced variations in cyclic AMP content of the superovulated preimplantation mouse embryo.
Topics: Animals; Cyclic AMP; Embryo, Mammalian; Embryonic Development; Female; In Vitro Techniques; Lethal D | 1975 |
[Lipids in pregnant patients with severe course of gestosis treated with xanthinol nicotinate and bufenin hydrochloride].
Topics: Cholesterol; Female; Humans; Lipids; Lipoproteins, LDL; Nylidrin; Pre-Eclampsia; Pregnancy; Theophyl | 1976 |
Possible interaction of cyclic nucleotides with the prolactin stimulation of casein synthesis in mouse mammary gland explants.
Topics: Animals; Bucladesine; Caseins; Cells, Cultured; Cyclic GMP; Female; Leucine; Mammary Glands, Animal; | 1976 |
Phospholipases and the effect of prolactin on uridine incorporation into RNA in mammary gland explants of mice.
Topics: Animals; Arachidonic Acids; Bucladesine; Cyclic GMP; Female; Indomethacin; Mammary Glands, Animal; O | 1976 |
Effects of prostaglandin E2 on adenosine-3',5'-monophosphate accumulation and progesterone synthesis in human corpora lutea in vitro.
Topics: Bucladesine; Chorionic Gonadotropin; Corpus Luteum; Cyclic AMP; Dose-Response Relationship, Drug; Fe | 1976 |
Regulation of enzyme turnover during tissue differentiation. Interactions of insulin, prolactin and cortisol in controlling the turnover of fatty acid synthetase in rabbit mammary gland in organ culture.
Topics: Animals; Bucladesine; Caseins; Cell Differentiation; Fatty Acid Synthases; Female; Hydrocortisone; I | 1976 |
Failure of 1, 25 dihydroxycholecalciferol (1, 25-(OH) 2-D3) to modify cyclic AMP levels in parathyroid hormone-treated and untreated bone cells.
Topics: Animals; Bone and Bones; Cells, Cultured; Cyclic AMP; Dihydroxycholecalciferols; Female; Fetus; Hydr | 1976 |
Effect of Indomethacin on cyclic AMP phosphodiesterase activity in myometrium from pregnant rhesus monkeys.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Caffeine; Drug Synergism; Epinephrine; Female; Haplorh | 1976 |
The influence of theophylline on the motility and the cyclic 3',5'-AMP content in the pregnant and non-pregnant rat uterus in vitro.
Topics: Animals; Cyclic AMP; Dose-Response Relationship, Drug; Female; Pregnancy; Rats; Theophylline; Uterin | 1976 |
Oestrogen formation from C19 precursors in human choriocarcinoma in culture.
Topics: Algestone; Androgens; Androstenedione; Bucladesine; Cell Line; Cholesterol; Choriocarcinoma; Clone C | 1977 |
Cyclic 3'5'-adenosine monophosphate in the hypothalamo-neurohypophysial system of normal, NaCl-treated and lactating rats.
Topics: Acetylcholine; Animals; Carbachol; Cyclic AMP; Dehydration; Female; Hypothalamus; Lactation; Male; P | 1976 |
Cyclic nucleotide phosphodiesterase activities of the fetal and mature human cerebral cortex.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adolescent; Adult; Carrier Proteins; Cerebral Cortex; Cyclic AM | 1977 |
Immunologic and physical characterization of human chorionic gonadotropin and its subunits in cultures of human malignant trophoblast.
Topics: Antigens; Bucladesine; Cells, Cultured; Chorionic Gonadotropin; Female; Humans; Macromolecular Subst | 1977 |
Effect of cyclic 3':5'-AMP derivatives prostaglandins and related agents on human chorionic gonadotropin secretion in human malignant trophoblast in culture.
Topics: Adenine; Adenylyl Cyclases; Bucladesine; Cell Line; Chorionic Gonadotropin; Cyclic AMP; Female; Fluo | 1977 |
[3'5'-Cyclic AMP phosphodiesterase activity in the internal and external layers of human myometrium at the end of pregnancy].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Caffeine; Female; Humans; Imidazoles; Indomethacin; Kinetics; M | 1977 |
Effect of cyclic AMP on placental active transport of amino acid in rats.
Topics: Amino Acids; Animals; Biological Transport, Active; Bucladesine; Cyclic AMP; Female; Fetus; Liver; L | 1978 |
Electrophysiological effects effects of prostaglandin F 2 alpha and E1 on the oviduct of the pregnant guinea pig in relation to Ca++.
Topics: Action Potentials; Animals; Bucladesine; Calcium; Cations, Divalent; Fallopian Tubes; Female; Guinea | 1978 |
Oral administration of theophylline to modify pressor responsiveness to angiotensin II in women with pregnancy-induced hypertension.
Topics: Angiotensin II; Blood Pressure; Cyclic AMP; Female; Humans; Hypertension; Pregnancy; Pregnancy Compl | 1978 |
Effects of cyclic AMP altering drugs on endotoxin-induced termination of pregnancy.
Topics: Abortion, Spontaneous; Animals; Bucladesine; Cyclic AMP; Endotoxins; Female; Mice; Pregnancy; Propra | 1979 |
Effects of butyrate and dibutyryl cyclic AMP on hCG-secreting trophoblastic and non-trophoblastic cells.
Topics: Adult; Breast Neoplasms; Bucladesine; Butyrates; Carcinoma, Squamous Cell; Cell Line; Choriocarcinom | 1978 |
Effects of culture conditions on the synthesis of human chorionic gonadotropin by placental organ cultures.
Topics: Bucladesine; Chorionic Gonadotropin; Culture Media; DNA; Female; Humans; Organ Culture Techniques; O | 1979 |
Iatrogenic congenital goiter and hypothyroidism with respiratory distress in a newborn.
Topics: Asthma; Congenital Hypothyroidism; Ephedrine; Female; Goiter; Humans; Hypothyroidism; Infant, Newbor | 1978 |
[Effect of various chemical substances on transplacental passage of Streptococcus].
Topics: Animals; Cell Membrane Permeability; Cervix Uteri; Female; Histamine; Hyaluronoglucosaminidase; Mate | 1979 |
Placental transfer of theophylline.
Topics: Biological Transport, Active; Female; Fetus; Humans; Infant, Newborn; Maternal-Fetal Exchange; Place | 1979 |
Placental transfer of theophylline: two case reports.
Topics: Administration, Oral; Aminophylline; Asthma; Female; Fetus; Humans; Infant, Newborn; Infant, Newborn | 1979 |
Vascular responsiveness to pressor agents during human pregnancy.
Topics: Aldosterone; Angiotensin II; Aspirin; Female; Hematocrit; Humans; Hypertension; Indomethacin; Pregna | 1979 |
Reliable detection of cystic fibrosis in skin-derived fibroblast cultures.
Topics: Alkaline Phosphatase; Cells, Cultured; Cystic Fibrosis; Enzyme Induction; Female; Fibroblasts; Glyco | 1978 |
1-(Theophyllin-7-yl)-ethyl-2-[2-(p-chlorophenoxy)-2-methylpropionate] (ML 1024), a new hypolipemic agent.
Topics: Animals; Blood Pressure; Dogs; Female; Hyperlipidemias; Male; Mice; Pregnancy; Propionates; Rabbits; | 1977 |
Studies on the haemodynamic action of complamin in pregnancy.
Topics: Adult; Blood Volume; Female; Hemodynamics; Humans; Placenta; Pregnancy; Pregnancy Trimester, Third; | 1977 |
[The effect of Complamine on human uteroplacental hemodynamics (proceedings)].
Topics: Blood Volume; Female; Hemodynamics; Humans; Nicotinic Acids; Placenta; Pregnancy; Pregnancy Complica | 1977 |
[Influence of different obstetric-manipulations on the continuous measured pO2-tension upon the fetus sub partu (author's transl)].
Topics: Delivery, Obstetric; Female; Fenoterol; Fetus; Hemodynamics; Humans; Labor, Obstetric; Nicotinic Aci | 1978 |
Ultrastructural changes in lactating guinea pig mammary gland slices associated with theophylline inhibition of lactose synthesis.
Topics: Animals; Cytoplasmic Granules; Female; Golgi Apparatus; Guinea Pigs; In Vitro Techniques; Lactation; | 1978 |
Transient diabetes mellitus in a neonate. Evaluation of insulin, glucagon, and growth hormone secretion and management with a continuous low-dose insulin infusion.
Topics: Adolescent; Antigens; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance | 1977 |
Assay of perinatal testosterone and influence of anti-progesterone and theophylline on induction of sterility.
Topics: Animals; Animals, Newborn; Estrus; Female; Immune Sera; Infertility, Female; Male; Pregnancy; Proges | 1977 |
[Simultaneous study of the placental, myometrial and cervical circulations (indium 113 and anemometric thermometry). 2. Effect of xanthinol nicotinate].
Topics: Adult; Cervix Uteri; Female; Humans; Indium; Isotopes; Myometrium; Placenta; Pregnancy; Regional Blo | 1976 |
[Xanthinol nicotinate and bufenin hydrochloride in the treatment of gestosis].
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Theophylline; Xanthinol Niacinate | 1976 |
Post-implantation termination of pregnancy in rats.
Topics: Abortifacient Agents; Alkaline Phosphatase; Aminoglutethimide; Animals; Cyclofenil; Diethylstilbestr | 1976 |
Theophylline secretion into breast milk.
Topics: Adult; Affective Symptoms; Breast Feeding; Female; Half-Life; Humans; Infant; Kinetics; Milk, Human; | 1976 |
[Pharmacokinetic examination of theophylline in pregnancy in cases of fetal anoxia].
Topics: Amniotic Fluid; Female; Fetal Hypoxia; Fetus; Half-Life; Humans; Maternal-Fetal Exchange; Pregnancy; | 1992 |
Plasma adenosine and cardiovascular responses to dipyridamole in fetal sheep.
Topics: Adenosine; Animals; Blood Pressure; Dipyridamole; Female; Fetus; Gestational Age; Heart Rate, Fetal; | 1992 |
Quantitative relationships between cyclic adenosine-3',5'-monophosphate and lipolysis in adipose tissue during the peripartum period.
Topics: Adenosine Deaminase; Adipose Tissue; Animals; Body Weight; Cattle; Cyclic AMP; Eating; Female; Glyce | 1992 |
Physiological activities of late-gestation rat fetuses in vitro.
Topics: Animals; Central Nervous System; Decerebrate State; Electrophysiology; Female; Fetal Movement; Fetus | 1992 |
Lymphocyte subpopulations in peripheral blood of pregnant sows.
Topics: Animals; B-Lymphocyte Subsets; Female; Lymphocyte Subsets; Pregnancy; Pregnancy, Animal; Swine; T-Ly | 1992 |
Theophylline transfer across human placental cotyledon during in vitro dual perfusion.
Topics: Female; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Models, Biological; Perfusion; Placent | 1992 |
Patterns of secretion of human chorionic gonadotrophin by superfused placental explants and the embryo--placental relationship following maternal use of medications.
Topics: Chorionic Gonadotropin; Codeine; Diclofenac; Female; Humans; Lorazepam; Maternal-Fetal Exchange; Org | 1992 |
Cerebrovascular reactivity to adenosine analogues in 0.6-0.7 gestation and near-term fetal sheep.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Cerebrovascular Circulation; Fema | 1992 |
In situ perfusion in the rabbit: effects of different umbilical flow rates on placental transfer of compounds.
Topics: Analysis of Variance; Animals; Antipyrine; Female; Kinetics; Maternal-Fetal Exchange; Perfusion; Pre | 1992 |
[Monitoring the effects of oxyphilline Spofa in the umbilical-placental circulation].
Topics: Female; Fetal Growth Retardation; Humans; Placenta; Pregnancy; Regional Blood Flow; Theophylline; Um | 1992 |
Synthesis and secretion of human chorionic gonadotropin and its subunits in choriocarcinoma cells: a comparative study with normal placental cells.
Topics: Acetylglucosaminidase; alpha-N-Acetylgalactosaminidase; Amidohydrolases; Bucladesine; Carbohydrate S | 1990 |
Enhancement by theophylline of the butyrate-mediated induction of choriogonadotropin alpha-subunit in HeLa cells. I. Lack of correlation with cAMP.
Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Colforsin; Drug Synergism; Female; Glycoprotein Hormo | 1990 |
Somatic development of the infant monkey following in utero exposure to caffeine.
Topics: Animals; Body Weight; Caffeine; Female; Half-Life; Humans; Infant, Newborn; Macaca fascicularis; Mal | 1991 |
The effect of centrally administered adenosine on fetal breathing movements.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Female; Fetus; Hydrogen-Ion Concentration; Inj | 1991 |
Placental transfer of theophylline during in situ perfusion in the rabbit.
Topics: Animals; Blood Gas Analysis; Chromatography, High Pressure Liquid; Female; Models, Biological; Perfu | 1991 |
Dissociation between the effects of theophylline and caffeine on premature airway smooth muscles.
Topics: Acetylcholine; Animals; Animals, Newborn; Caffeine; Disease Models, Animal; Female; Humans; Infant, | 1991 |
Fetal breathing, sleep state, and cardiovascular responses to adenosine in sheep.
Topics: Adenosine; Animals; Blood Pressure; Carbon Dioxide; Cerebral Cortex; Female; Fetal Blood; Fetal Hypo | 1990 |
Modulators of cyclic AMP metabolism induce syncytiotrophoblast formation in vitro.
Topics: Alkaline Phosphatase; Cell Differentiation; Cell Fusion; Cell Nucleus; Choriocarcinoma; Chorionic Go | 1990 |
The developmental toxicity of orally administered theophylline in rats and mice.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Cyclic AMP; Eating; Female; Fetal Resorp | 1990 |
The effect of methylxanthines on milk volume and composition, and growth of rat pups.
Topics: Animals; Animals, Newborn; Body Weight; Caffeine; Fatty Acids; Female; Lactation; Milk; Pregnancy; R | 1990 |
Effect of methylxanthines on lactational performance of rats.
Topics: Animals; Animals, Newborn; Body Weight; Caffeine; Drinking; Eating; Female; Lactation; Pregnancy; Ra | 1990 |
Cardiovascular anomalies associated with prenatal exposure to theophylline.
Topics: Adult; Asthma; Drug Administration Schedule; Female; Heart Defects, Congenital; Humans; Infant, Newb | 1990 |
Asthma and pregnancy: responsibility of physicians and patients.
Topics: Administration, Inhalation; Adult; Asthma; Beclomethasone; Ephedrine; Fear; Female; Health Planning | 1990 |
Characterization of theophylline binding to serum proteins in pregnant and nonpregnant women.
Topics: Adult; Blood Proteins; Fatty Acids, Nonesterified; Female; Fluorescence Polarization; Humans; Immuno | 1990 |
Maternal caffeine ingestion increases the tyrosine level in neonatal rat cerebrum.
Topics: Amino Acids; Animals; Animals, Newborn; Animals, Suckling; Brain; Caffeine; Female; Liver; Maternal- | 1990 |
Maternal theophylline consumption and the risk of stillbirth.
Topics: Asthma; Cohort Studies; Female; Fetal Death; Humans; Pregnancy; Pregnancy Complications; Prospective | 1990 |
Theophylline stimulates fetal breathing movements during hypoxia.
Topics: Adenosine; Animals; Female; Fetal Hypoxia; Fetus; Pregnancy; Respiratory Mechanics; Sheep; Theophyll | 1990 |
Effects of perinatal administration of isobutyl methylxanthine (IBMX) on [3H]-DA binding in the forebrain of the rat.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Binding, Competitive; Body Weight; Cyclic AMP; Diencephalon; D | 1986 |
Cyclic AMP inhibits the release of prostaglandins and arachidonic acid from cultures of mouse embryo palate mesenchyme cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Bucladesine; Cells, Cultu | 1986 |
Cyclic adenosine-3',5'-monophosphate stimulates the acute release of placental lactogen from human trophoblast cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Bucladesine; Cells, Cultured; Cholera Toxi | 1987 |
Effects of caffeine and 3-isobutyl 1-methyl xanthine on caprine milk secretion.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Fats; Female; Goats; Infusions, Intravenous; Injecti | 1988 |
Tissue culture of human fetal pancreas. Effects of nicotinamide on insulin production and formation of isletlike cell clusters.
Topics: Culture Techniques; Female; Glucose; Humans; Insulin; Islets of Langerhans; Niacinamide; Pancreas; P | 1989 |
Histamine and inositol phosphate accumulation in endothelium: cAMP and a G protein.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascula | 1989 |
Characterization of a developmental toxicity dose-response model.
Topics: Abnormalities, Drug-Induced; Animals; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Envi | 1989 |
[Asthma and pregnancy].
Topics: Asthma; Female; Humans; Prednisolone; Prednisone; Pregnancy; Pregnancy Complications; Theophylline | 1989 |
The mechanical response of rat myometrium to adenosine triphosphate in Ca-free solution.
Topics: Adenosine Triphosphate; Animals; Calcium; Cyclic AMP; Female; In Vitro Techniques; Papaverine; Potas | 1987 |
Pulmonary problems of pregnancy.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Asthma; Drug Therapy, Combination; Ethambutol; | 1985 |
Modulation of intracellular cyclic AMP content and rate of lipogenesis in mammary acini in vitro.
Topics: Acetyl-CoA Carboxylase; Animals; Cyclic AMP; Female; In Vitro Techniques; Insulin; Lactation; Lipids | 1986 |
Treatment of asthma.
Topics: Adrenergic beta-Agonists; Asthma; Breast Feeding; Cromolyn Sodium; Female; Fetal Hypoxia; Glucocorti | 1987 |
Influence of lactation upon pancreatic islet function.
Topics: Adenylyl Cyclases; Animals; Barium; Calcium; Calcium Chloride; Cyclic AMP; Female; Glucose; Insulin; | 1986 |
Evidence for physiological regulation of myometrial gap junction permeability.
Topics: 5,8,11,14-Eicosatetraynoic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; | 1986 |
Assessment of purine-dopamine interactions in 6-hydroxydopamine-lesioned rats: evidence for pre- and postsynaptic influences by adenosine.
Topics: Adenosine; Animals; Female; Hydroxydopamines; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Sy | 1988 |
[Chronic stimulation of the fibrinolytic system as supplementary treatment of intrauterine fetal hypotrophy].
Topics: Drug Therapy, Combination; Female; Fetal Growth Retardation; Fibrinolysis; Fibrinolytic Agents; Huma | 1988 |
[Pharmacokinetics of caffeine and dimethylxanthines in plasma and saliva].
Topics: Adult; Caffeine; Female; Humans; Male; Middle Aged; Models, Biological; Pregnancy; Saliva; Theophyll | 1988 |
Large-scale production of fetal porcine pancreatic isletlike cell clusters. An experimental tool for studies of islet cell differentiation and xenotransplantation.
Topics: Animals; Cell Differentiation; Cells, Cultured; Culture Media; DNA; Female; Fetus; Glucose; Insulin; | 1988 |
Nonprescription availability of antiasthma drugs.
Topics: Adult; Asthma; Canada; Child; Child, Preschool; Female; Humans; Infant; Nonprescription Drugs; Pregn | 1988 |
Theophylline neurotoxicity in pregnant rats.
Topics: Animals; Female; Fetal Blood; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Seizures; Th | 1988 |
Caffeine disposition in the pregnant rabbit. I. Pharmacokinetics following administration by intravenous bolus and continuous zero-order infusion.
Topics: Animals; Caffeine; Female; Infusion Pumps; Infusions, Intravenous; Kinetics; Male; Pregnancy; Pregna | 1988 |
Caffeine disposition in the pregnant rabbit. II. Fetal distribution of caffeine and paraxanthine during chronic maternal caffeine administration.
Topics: Albumins; Amniotic Fluid; Animals; Caffeine; Female; Fetal Proteins; Fetus; Infusions, Intravenous; | 1988 |
Reproductive effects of theophylline in mice and rats.
Topics: Animals; Estrus; Female; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Organ Size; Pregnanc | 1988 |
Adverse pregnancy outcome in the monkey (Macaca fascicularis) after chronic caffeine exposure.
Topics: Abortion, Veterinary; Animals; Birth Weight; Body Weight; Caffeine; Female; Fetal Death; Macaca fasc | 1988 |
Effects of different phosphodiesterase-inhibiting drugs on human pregnant myometrium: an in vitro study.
Topics: Female; Humans; In Vitro Techniques; Muscle Relaxation; Myometrium; Papaverine; Phosphodiesterase In | 1987 |
Effect of gestational hyperglycemia on insulin secretion in vivo and in vitro by fetal rat pancreas.
Topics: Animals; Female; Glucose; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Pregnancy | 1986 |
The lipolytic effects of mouse placental lactogen II, mouse prolactin, and mouse growth hormone on adipose tissue from virgin and pregnant mice.
Topics: Adipose Tissue; Animals; Female; Glycerol; Growth Hormone; Lipolysis; Mice; Placental Lactogen; Preg | 1987 |
Longitudinal effects of pregnancy on the pharmacokinetics of theophylline.
Topics: Asthma; Blood Proteins; Female; Humans; Kinetics; Metabolic Clearance Rate; Milk, Human; Pregnancy; | 1987 |
Evolution of the sensitivity of isolated adipocytes of ewes to the lipolytic effects of different stimuli during pregnancy and lactation.
Topics: Adenosine Deaminase; Adipose Tissue; Animals; Dexamethasone; Female; Growth Hormone; In Vitro Techni | 1987 |
Effects of maternal caffeine ingestion on the perinatal cerebrum.
Topics: Animals; Body Weight; Brain; Caffeine; Female; Fetus; Maternal-Fetal Exchange; Organ Size; Placenta; | 1987 |
[Asthma and pregnancy: peculiarities, therapeutic precautions].
Topics: Adrenal Cortex Hormones; Asthma; Breast Feeding; Female; Humans; Labor, Obstetric; Pregnancy; Pregna | 1987 |
[Asthma during pregnancy].
Topics: Adrenal Cortex Hormones; Aminophylline; Asthma; Atropine Derivatives; Female; Humans; Labor, Obstetr | 1987 |
Incidence of preeclampsia among asthmatic patients lower with theophylline.
Topics: Adult; Asthma; Female; Humans; Platelet Aggregation; Pre-Eclampsia; Pregnancy; Theophylline; Vascula | 1986 |
Theophylline pharmacokinetics in pregnancy.
Topics: Asthma; Blood Proteins; Female; Humans; Kinetics; Mathematics; Pregnancy; Pregnancy Complications; P | 1986 |
Theophylline clearance during pregnancy.
Topics: Adolescent; Adult; Asthma; Body Weight; Female; Humans; Kinetics; Postpartum Period; Pregnancy; Preg | 1986 |
[Effectiveness of teonikol in the treatment of patients with suppurative surgical infection and diabetes mellitus].
Topics: Aged; Conjunctiva; Diabetes Complications; Diabetic Angiopathies; Female; Hemodynamics; Humans; Lymp | 1986 |
Effect of chronic exposure to methylxanthines on diazepam cerebral binding in female rats and their offsprings.
Topics: Animals; Brain; Caffeine; Diazepam; Female; Lactation; Pregnancy; Pregnancy, Animal; Rats; Rats, Inb | 1986 |
[Fetal bigeminus following combined bronchodilator treatment of the mother].
Topics: Arrhythmias, Cardiac; Asthma; Drug Therapy, Combination; Electrocardiography; Female; Fetal Diseases | 1986 |
Theophylline pharmacokinetics in pregnant and lactating rats.
Topics: Animals; Body Burden; Female; Injections, Intraperitoneal; Kinetics; Lactation; Pregnancy; Pregnancy | 1986 |
Urinary metabolites of caffeine in pregnant women.
Topics: Caffeine; Female; Humans; Pregnancy; Theophylline; Uric Acid; Xanthines | 1986 |
Elimination of chronically consumed caffeine in the pregnant monkey (Macaca fascicularis).
Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Drinking; Eating; Female; Macaca fascicular | 1986 |
Teratogenicity of paraxanthine (1,7-dimethylxanthine) in C57BL/6J mice.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cleft Palate; Dose-Response Relationship, Drug; Fema | 1986 |
An aborted human fetus with truncus arteriosus communis--possible teratogenic effect of Tedral.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Drug Combinations; Embryo, Mammalian; Eph | 1985 |
[Detection of caffeine, theophylline and theobromine in the umbilical cord blood and breast milk].
Topics: Caffeine; Female; Fetal Blood; Humans; Infant, Premature; Kinetics; Maternal-Fetal Exchange; Milk, H | 1985 |
Effects of theophylline on small human placental arteries in vitro.
Topics: Dinoprost; Dinoprostone; Female; Humans; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; | 1985 |
Factors influencing theophylline disposition in 179 newborns.
Topics: Apgar Score; Asphyxia Neonatorum; Body Weight; Female; Gestational Age; Humans; Infant, Newborn; Inf | 1986 |
Reversal of theophylline toxicity using oral activated charcoal.
Topics: Administration, Oral; Adult; Charcoal; Female; Humans; Pregnancy; Pregnancy Complications; Theophyll | 1985 |
Influence of theophylline on fetal rat lung phosphatidylcholine synthesis in vivo.
Topics: Animals; Choline; Female; Fetus; Injections, Intraperitoneal; Kinetics; Lung; Phosphatidylcholines; | 1985 |
Enprofylline and theophylline on small human placental arteries: studies of in vitro effects and mode of action.
Topics: Arteries; Bronchodilator Agents; Calcium; Dose-Response Relationship, Drug; Female; Humans; In Vitro | 1985 |
[Determination of theophylline and caffeine in blood serum by thin-layer chromatography-densitometry].
Topics: Caffeine; Chromatography, Thin Layer; Densitometry; Evaluation Studies as Topic; Female; Fetal Blood | 1985 |
Theophylline and fibrocystic breast disease.
Topics: Adult; Age Factors; Asthma; Caffeine; Estrogens; Female; Fibrocystic Breast Disease; Humans; Menopau | 1985 |
The effect of caffeine ingestion on pharmacokinetics of caffeine and its metabolites after a single administration in pregnant rats.
Topics: Administration, Oral; Animals; Caffeine; Female; Injections, Intravenous; Kinetics; Pregnancy; Rats; | 1985 |
Polymorphism of theophylline metabolism in man.
Topics: Acetylation; Adolescent; Adult; Cholinesterases; Female; Glucosephosphate Dehydrogenase Deficiency; | 1985 |
Caffeine disposition after oral administration to pregnant rats.
Topics: Administration, Oral; Amniotic Fluid; Animals; Caffeine; Female; Fetus; Pregnancy; Rats; Theobromine | 1985 |
[Determination of caffeine and dimethylxanthines in biological fluids and tissues by high performance liquid chromatography].
Topics: Animals; Body Fluids; Caffeine; Chromatography, High Pressure Liquid; Female; Pregnancy; Rats; Theop | 1985 |
Theophylline toxicity in a preterm infant: selected clinical aspects.
Topics: Adult; Blood Cell Count; Charcoal; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Pre | 1985 |
Enzyme induction in human fetal liver in organ culture.
Topics: Animals; Arginine; Bucladesine; Carbon Radioisotopes; Cycloheximide; Dexamethasone; Female; Fetus; G | 1973 |
Inhibition of the oxytocic action of prostaglandin F2alpha on pregnant rabbit uterus by intra-aortic infusion of theophylline in vivo.
Topics: Anesthesia, General; Animals; Aorta, Abdominal; Female; Injections, Intra-Arterial; Muscle Contracti | 1974 |
Adenyl cyclase activity in the rabbit ovary.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals | 1969 |
Adenosine 3',5' monophosphate as an inhibitor of ovulation and reproduction.
Topics: Adenine Nucleotides; Animals; Chorionic Gonadotropin; Cyclic AMP; Female; In Vitro Techniques; Mice; | 1969 |
The stimulatory effect of luteinizing hormone on adenyl cyclase in the bovine corpus luteum.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals | 1970 |
A parathyroid hormone-like action of dibutyryl cyclic adenosine-3', 5'-monophosphate on the explanted embryonic mouse radius.
Topics: Adenine Nucleotides; Animals; Bone and Bones; Cartilage; Cyclic AMP; Female; In Vitro Techniques; Mi | 1970 |
Adenosine 3',5'-cyclic phosphate phosphodiesterase of corpus luteum.
Topics: Animals; Caffeine; Cattle; Corpus Luteum; Cyclic AMP; Estrus; Female; Humans; Hydrogen-Ion Concentra | 1971 |
Differential release of individual gonadotrophins by the human foetal pituitary gland after stimulation by cyclic AMP and sodium fluoride.
Topics: Adenine Nucleotides; Cyclic AMP; Female; Fluorides; Follicle Stimulating Hormone; Humans; Luteinizin | 1971 |
Effect of theophylline on glucagon and glucose-mediated plasma insulin responses in subhuman primate fetus and neonate.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Cyclic AMP; Female; Fetus; Glucagon; Glucose; Growth H | 1971 |
Insulin release from human fetal pancreas in vitro.
Topics: Arginine; Barium; Body Weight; Cyclic AMP; Female; Fetus; Gestational Age; Glucagon; Glucose; Humans | 1971 |
The mode of action of dibutyryl adenosine 3',5'-monophosphate on bone tissue in vitro.
Topics: Adenosine; Adenosine Monophosphate; Animals; Animals, Newborn; Body Fluids; Bone and Bones; Butyrate | 1971 |
[Demonstration of 3'5'-cyclic AMP phosphodiesterase activity in the human placenta at term].
Topics: Caffeine; Cyclic AMP; Epinephrine; Female; Fluorides; Humans; Imidazoles; Luteinizing Hormone; Norep | 1972 |
Cyclic 3',5'-adenosine monophosphate response in the rabbit lung--adult properties and development.
Topics: Age Factors; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Female; Fetus; Hear | 1972 |
[Inhibition of uterine contraction. Several aspects and relationships with cyclic AMP].
Topics: Adult; Animals; Cyclic AMP; Drug Antagonism; Female; Fetal Heart; Heart Rate; Humans; In Vitro Techn | 1972 |
Differential effect of cyclic adenosine monophosphate on the secretion of human placental lactogen and human chorionic gonadotropin.
Topics: Chorionic Gonadotropin; Cyclic AMP; Female; Humans; In Vitro Techniques; Placenta; Placental Lactoge | 1973 |
Maturation of responsiveness to cardioactive drugs. Differential effects of acetylcholine, norepinephrine, theophylline, tyramine, glucagon, and dibutyryl cyclic AMP on atrial rate in hearts of fetal mice.
Topics: Acetylcholine; Animals; Atrial Function; Butyrates; Culture Media; Cyclic AMP; Female; Fetal Heart; | 1973 |
Rat uterine contractility and the activities of uterine adenyl cyclase and phosphodiesterase during the estrus cycle.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Estrus; Female; In Vitro T | 1973 |
[In vitro synthesis of progesterone in human cyclic corpus luteum: action of prostaglandin F2alpha].
Topics: Aspirin; Carbon Radioisotopes; Chorionic Gonadotropin; Corpus Luteum; Cyclic AMP; Drug Synergism; Fe | 1973 |
Lack of effect of erythropoietin on cyclic adenosine-3',5'-monophosphate levels in rat fetal liver cells.
Topics: Animals; Cyclic AMP; Epinephrine; Erythropoietin; Female; Heme; Iron; Iron Radioisotopes; Liver; Pre | 1974 |
Adenylate cyclase activity in immature rabbit lung.
Topics: Adenylyl Cyclases; Age Factors; Animals; Animals, Newborn; Cyclic AMP; Epinephrine; Female; Fetus; F | 1974 |
The effects of epinephrine and prostaglandin E-1 on cyclic adenosine 3':5'-monophosphate levels in WI-38 fibroblasts.
Topics: Adrenocorticotropic Hormone; Cell Line; Culture Media; Cyclic AMP; Diploidy; Drug Synergism; Epineph | 1974 |
Hormonal regulation of collagen degradation in the uterus: inhibition of collagenase expression by progesterone and cyclic AMP.
Topics: Animals; Bucladesine; Collagen; Cyclic AMP; Female; Hydroxyproline; Leucine; Medroxyprogesterone; Mi | 1974 |
Hormonal regulation of amino acid accumulation in human fetal liver explants. Effects of dibutyryl cyclic AMP, glucogon and insulin.
Topics: Alanine; Aminoisobutyric Acids; Biological Transport; Bucladesine; Carbon Radioisotopes; Cycloheximi | 1974 |
Independent dibutyryl cyclic adenosine monophosphate stimulation of human chorionic gonadotropin and estrogen secretion by malignant trophoblast cells in vitro.
Topics: Blood; Bucladesine; Cell Line; Chorionic Gonadotropin; Cycloheximide; Estradiol; Estrone; Female; Hu | 1974 |
Inhibition of lipolysis in bovine adipose tissue by butyrate and beta-hydroxybutyrate.
Topics: Adipose Tissue; Animals; Bucladesine; Butyrates; Cattle; Dose-Response Relationship, Drug; Fatty Aci | 1974 |
The effect of theophylline on oxytocin induced contractions in the chronically catheterized pregnant rabbit.
Topics: Adrenocorticotropic Hormone; Animals; Catheterization; Female; Infusions, Parenteral; Muscle Contrac | 1974 |
Induction of tyrosine aminotransferase and amino acid transport in Morris hepatomas and in adult and neonatal rat liver.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Animals, Newborn; Biological Transport; Carbon Isotopes | 1971 |
[Research on the fibrinolytic effects developed in vivo from 7-(2-[pyrid(3)yl-methylamino]ethyl) theophylline nicotinate. Preliminary note].
Topics: Dosage Forms; Female; Fibrinolysis; Humans; Male; Methylamines; Nicotinic Acids; Pregnancy; Pyridine | 1974 |
Fetal hypoproteinemia associated with generalized edema caused by administration of methyl xanthines to the rat during late pregnancy.
Topics: Animals; Blood Proteins; Body Water; Body Weight; Caffeine; Edema; Female; Fetal Diseases; Fetus; Ge | 1973 |
Effects of pregnancy in the rat on the size and insulin secretory response of the islets of Langerhans.
Topics: Adenylyl Cyclases; Animals; Arginine; Blood Glucose; DNA; Female; Glucagon; Glucose; In Vitro Techni | 1972 |
The ontogeny of insulin secretion mechanisms.
Topics: Age Factors; Animals; Animals, Newborn; Biological Evolution; Drug Synergism; Female; Gestational Ag | 1973 |
[Atypical course in postpartum eclampsia? A case report].
Topics: Adult; Chlorpromazine; Diazepam; Eclampsia; Female; Humans; Hypertension; Infant, Newborn; Infant, P | 1972 |
[Behavior of placental lactogen level in serum and estradiol excretion in pregnant women under the treatment for EPH (edema, proteinuria, hypertension) gestosis with heparin and complamin].
Topics: Edema; Estradiol; Female; Heparin; Humans; Hypertension; Nicotinic Acids; Placental Lactogen; Pre-Ec | 1972 |
Continuous recording of uteroplacental blood volume in the human.
Topics: Adult; Blood Flow Velocity; Blood Volume; Blood Volume Determination; Female; Humans; Indium; Matern | 1973 |
The effect of oxygen ventilation and a vasodilator on uterine perfusion, foetal oxygen and acid-base balance. I. A study in healthy gravidae.
Topics: Acid-Base Equilibrium; Carbon Dioxide; Female; Fetus; Humans; Maternal-Fetal Exchange; Nicotinic Aci | 1973 |
Triploidy 69, XXX in a stillborn girl.
Topics: Adult; Asthma; Chromatids; Chromosome Aberrations; Chromosomes, Human, 1-3; Chromosomes, Human, 13-1 | 1973 |
[Changes in serum electrolytes, serum proteins and substances, normally contained in the urine during therapy of feto-placentar insufficiency using xantinol nicotinate and heparin].
Topics: Adult; Blood Proteins; Electrolytes; Female; Humans; Infant; Infant, Newborn; Male; Nicotinic Acids; | 1973 |
The effect of oxygen ventilation and vasodilator on uterine perfusion, fetal oxygen and acid-base balance. I. A study in abnormal gravidae.
Topics: Acid-Base Equilibrium; Anemia; Asphyxia Neonatorum; Erythroblastosis, Fetal; Female; Fetus; Humans; | 1973 |
Identification of drugs in the preimplantation blastocyst and in the plasma, uterine secretion and urine of the pregnant rabbit.
Topics: Animals; Barbiturates; Caffeine; Carbon Isotopes; DDT; Embryo Implantation; Endometrium; Female; Iso | 1971 |
[Effect of glucagon or arginine on milk cow calcemia and phosphatemia].
Topics: Adenylyl Cyclases; Animals; Arginine; Calcitonin; Cattle; Cattle Diseases; Female; Glucagon; Hypocal | 1970 |
The teratological effect of benzolamide, a new carbonic anhydrase inhibitor.
Topics: Abnormalities, Drug-Induced; Acid-Base Equilibrium; Animals; Carbonic Anhydrase Inhibitors; Female; | 1972 |
[Etiology of heart rate disorders in the mature sheep fetus].
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Carbon Dioxide; Female; Fetal Heart; Heart Rate; Hydr | 1971 |
The effect of variations in the oxygen content of maternal blood on the perfusion of the uterus and on the oxygen and Astrupp values of the fetus.
Topics: Blood; Cervix Uteri; Female; Fetal Hemoglobin; Fetus; Humans; Hydrogen-Ion Concentration; Maternal-F | 1971 |
Teratogenic actions of some methylated xanthines in mice.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Female; Fetus; Injections, Intraperitoneal; Male; Mi | 1969 |
[Prevention of fetal asphyxia with theophylline drugs].
Topics: Asphyxia Neonatorum; Electrocardiography; Female; Fetal Death; Fetal Diseases; Heart Rate; Humans; I | 1970 |
[Mechanism of hormonal regulation in human placenta. I. Presence of adenyl cyclase activity in human full-term homogenates].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Adenylyl Cyclases; Cell Fractionation; Enzyme Activatio | 1971 |
[Modern considerations on the obstetrical and pharmacological treatment of patients with eclampsia. (Clinico-statistical study)].
Topics: Adult; Anesthesia, Obstetrical; Antihypertensive Agents; Delivery, Obstetric; Diuretics; Eclampsia; | 1968 |
[On the use of complamin in obstetrics. Preliminary report].
Topics: Dystocia; Female; Fetus; Humans; Muscles; Nicotinic Acids; Pregnancy; Theophylline | 1968 |
[Improved wound healing and thrombosis prevention following gynecological and obstetrical surgery: clinical experience with a new aristolochic acid containing drug].
Topics: Adolescent; Adult; Female; Genital Diseases, Female; Humans; Middle Aged; Obstetric Labor Complicati | 1966 |