Page last updated: 2024-10-22

theophylline and Pneumonia

theophylline has been researched along with Pneumonia in 29 studies

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"Theophylline disposition (clearance, volume of distribution, and half-life) was measured in 31 normal volunteers and 26 acutely ill patients with airway obstruction within 24 hours of hospital admission and again when intravenous aminophylline was discontinued 2 to 10 days later."7.66Theophylline disposition in acutely ill hospitalized patients. The effect of smoking, heart failure, severe airway obstruction, and pneumonia. ( Costello, J; Hopewell, P; Powell, JR; Riegelman, S; Sheiner, LB; Vozeh, S, 1978)
" The patient later developed pneumonia and was enrolled in a study of nosocomial acquired pneumonia involving clinafloxacin versus ceftazidime."5.08Clinafloxacin-theophylline drug interaction. ( Matuschka, PR; Vissing, RS, 1995)
"In order to determine the efficacy and safety of the new quinolone ofloxacin in the treatment of chronic lower respiratory disease, 674 patients (353 with chronic bronchitis, 212 with community-acquired pneumonia and 109 with hospital-acquired pneumonia) were treated with ofloxacin 200 mg twice a day."3.68Ofloxacin in lower respiratory tract infections. ( Petermann, W, 1991)
" The infection coincided with neutropenia resulting from pyrazolone treatment."3.67Trichosporon beigelii pneumonia in a neutropenic patient. ( Borras, R; Chiner, E; Franco, J; Marin, J, 1989)
"Theophylline disposition (clearance, volume of distribution, and half-life) was measured in 31 normal volunteers and 26 acutely ill patients with airway obstruction within 24 hours of hospital admission and again when intravenous aminophylline was discontinued 2 to 10 days later."3.66Theophylline disposition in acutely ill hospitalized patients. The effect of smoking, heart failure, severe airway obstruction, and pneumonia. ( Costello, J; Hopewell, P; Powell, JR; Riegelman, S; Sheiner, LB; Vozeh, S, 1978)
"Theophylline is a difficult drug to use clinically, requiring careful titration and routine plasma monitoring due to the risk of toxic side effects, such as cardiovascular and central nervous system adverse events, with dose adjustments required in many patients, including smokers, the elderly and some patients on concomitant medications."2.42PDE4 inhibitors in COPD--a more selective approach to treatment. ( Vignola, AM, 2004)
"Doxofylline is a xanthine drug that has been used as a treatment for respiratory diseases for more than 30 years."1.40Doxofylline, a novofylline inhibits lung inflammation induced by lipopolysacharide in the mouse. ( Man, F; Page, CP; Riffo-Vasquez, Y, 2014)
"In the second model, in blood of COPD-patients and healthy controls ex vivo pre-incubated with a physiological concentration of 1,7-dimethylxanthine (10microM), LPS-induced production of the cytokines IL-6 and TNF-alpha was significantly suppressed."1.36Inhibition of acute pulmonary and systemic inflammation by 1,7-dimethylxanthine. ( Bast, A; Brauers, K; Geraets, L; Haegens, A; Hageman, GJ; Vernooy, JH; Weseler, AR; Wouters, EF, 2010)
"582 case records of patients with cancer of the larynx have been examined for associated bronchopulmonary disease."1.30[Bronchopulmonary complications in patients with laryngeal cancer: features of preoperative care]. ( Malinin, AN; Smetanin, IG, 1998)
"Enoxacin is a safe and effective alternative to parenteral treatment of lower respiratory tract infections."1.27Enoxacin in the treatment of lower respiratory tract infections. ( Arnaud, A; Frances, Y; Nourrit, J; Philip-Joet, F, 1988)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199014 (48.28)18.7374
1990's7 (24.14)18.2507
2000's5 (17.24)29.6817
2010's3 (10.34)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Riffo-Vasquez, Y2
Venkatasamy, R1
Page, CP2
Man, F1
Stiefelhagen, P2
Geraets, L1
Haegens, A1
Weseler, AR1
Brauers, K1
Vernooy, JH1
Wouters, EF1
Bast, A1
Hageman, GJ1
Balfour-Lynn, IM1
Elborn, JS1
FISCHER, W1
KRUMBHOLZ, S1
TAUB, SJ1
KUSZTOS, D1
HAFFNER, Z1
Vignola, AM1
Misawa, D1
Ohshima, K1
Watanabe, M1
Asai, K1
Ino, T1
Ueda, M1
Morgan, WJ1
Taussig, LM1
Nikki, P1
Meretoja, O1
Valtonen, V1
Mäkeläinen, A1
Saikku, P1
Mattila, S1
Taskinen, E1
Flenley, DC1
Matuschka, PR1
Vissing, RS1
Jaspersen, D1
Lilley, LL1
Guanci, R1
Smetanin, IG1
Malinin, AN1
Vozeh, S2
Powell, JR2
Riegelman, S2
Costello, JF1
Sheiner, LB2
Hopewell, PC1
Hopewell, P1
Costello, J1
Vaquero Peña, MA1
Martín Arias, LH1
Saldana Garrido, D1
Carvajal García-Pando, A1
Petermann, W1
Boner, AL1
Piacentini, GL1
Peroni, DG1
Bacchini, P1
Franco, L1
Velo, G1
Bellanti, JA1
Marin, J1
Chiner, E1
Franco, J1
Borras, R1
Philip-Joet, F1
Nourrit, J1
Frances, Y1
Arnaud, A1
Späth, G1
Marx, HH1
Pulyk, PM1
Levine, ER1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy Of Doxophylline As A Sparing Treatment For Inhaled Corticosteroids In Mexican Children With Asthma[NCT03879590]Phase 360 participants (Anticipated)Interventional2019-05-31Not yet recruiting
[NCT00005279]0 participants Observational1971-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for theophylline and Pneumonia

ArticleYear
"CF asthma": what is it and what do we do about it?
    Thorax, 2002, Volume: 57, Issue:8

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Asthma; Bronchial Hyperreactivity; Bronchodila

2002
PDE4 inhibitors in COPD--a more selective approach to treatment.
    Respiratory medicine, 2004, Volume: 98, Issue:6

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyridines; Benzamides; Bronchodilator Agents; Carboxylic A

2004
The chronic bronchitis complex in children.
    Pediatric clinics of North America, 1984, Volume: 31, Issue:4

    Topics: Adrenergic beta-Agonists; Adult; Age Factors; Air Pollution; Anti-Bacterial Agents; Asthma; Bronchit

1984
Recent advances in respiratory medicine.
    Postgraduate medical journal, 1983, Volume: 59, Issue:687

    Topics: Adult; Aged; Anti-Bacterial Agents; Asthma; Bronchitis; Cephalosporins; Child; Humans; Immunosuppres

1983
[Reflux associated respiratory tract diseases].
    Deutsche medizinische Wochenschrift (1946), 1996, Apr-05, Volume: 121, Issue:14

    Topics: Bronchiectasis; Bronchitis; Bronchodilator Agents; Chronic Disease; Esophagogastric Junction; Gastro

1996
[The acute respiratory insufficiency].
    Munchener medizinische Wochenschrift (1950), 1972, Nov-17, Volume: 114, Issue:46

    Topics: Acute Disease; Asthma; Blood Gas Analysis; Bronchitis; Butyrates; Chronic Disease; Cortisone; Electr

1972

Trials

1 trial available for theophylline and Pneumonia

ArticleYear
Clinafloxacin-theophylline drug interaction.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:4

    Topics: Aged; Anti-Infective Agents; Cross Infection; Delayed-Action Preparations; Drug Interactions; Drug M

1995

Other Studies

22 other studies available for theophylline and Pneumonia

ArticleYear
Steroid sparing effects of doxofylline.
    Pulmonary pharmacology & therapeutics, 2018, Volume: 48

    Topics: Animals; Bronchodilator Agents; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, D

2018
Doxofylline, a novofylline inhibits lung inflammation induced by lipopolysacharide in the mouse.
    Pulmonary pharmacology & therapeutics, 2014, Volume: 27, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Bronchodilator Agents; Cell Movement; Disease Models, Animal; Dos

2014
[COPD and pneumonia therapy in the elderly. What is different in aging lungs].
    MMW Fortschritte der Medizin, 2008, Oct-23, Volume: 150, Issue:43

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Aged; Bronchodilator Agents; Comorbidity; Dose-Re

2008
[Pulmonary diseases in pregnancy. What drugs are permitted?].
    MMW Fortschritte der Medizin, 2009, Mar-05, Volume: 151, Issue:10

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antitubercular Agents;

2009
Inhibition of acute pulmonary and systemic inflammation by 1,7-dimethylxanthine.
    European journal of pharmacology, 2010, Mar-10, Volume: 629, Issue:1-3

    Topics: Administration, Oral; Aged; Animals; Anti-Inflammatory Agents; Benzamides; Case-Control Studies; Cyt

2010
[CONSIDERATIONS ON THE RELATION BETWEEN CEREBRAL AND PULMONARY BLOOD FLOW UNDER THE INFLUENCE OF ANESTHESIA AND BRAIN SURGERY (WITH USE OF A THEOPHYLLINE- PYRAZOLONE COMBINATION PREPARATION)].
    Neurochirurgia, 1963, Volume: 6

    Topics: Aminopyrine; Anesthesia; Brain; Brain Neoplasms; Bronchitis; Bronchopneumonia; Cerebrovascular Circu

1963
THE DIAGNOSIS AND TREATMENT OF ASTHMA IN THE ELDERLY.
    Geriatrics, 1964, Volume: 19

    Topics: Aerosols; Aged; Asthma; Betamethasone; Bronchiectasis; Bronchitis; Dexamethasone; Dyspnea; Dyspnea,

1964
[USE OF PERIPHERIN-HOMBURG IN CIRCULATORY DISEASES OF THE BRAIN].
    Orvosi hetilap, 1964, May-24, Volume: 105

    Topics: Brain; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebrovascular Disorders; Ephedrine; Humans; I

1964
[Rhabdomyolysis: case report of 11 patients].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2005, Jul-10, Volume: 94, Issue:7

    Topics: Adult; Aged; Enteritis; Female; Humans; Hypokinesia; Influenza A virus; Influenza, Human; Male; Midd

2005
Severe bronchiolitis probably caused by varicella-zoster virus.
    Critical care medicine, 1982, Volume: 10, Issue:5

    Topics: Adult; Biopsy; Bronchi; Bronchiolitis, Viral; Chickenpox; Herpesvirus 3, Human; Humans; Hypercapnia;

1982
Avoiding adverse reactions.
    The American journal of nursing, 1996, Volume: 96, Issue:9

    Topics: Antacids; Anti-Infective Agents; Asthma; Bronchodilator Agents; Ciprofloxacin; Drug Interactions; Hu

1996
[Bronchopulmonary complications in patients with laryngeal cancer: features of preoperative care].
    Vestnik otorinolaringologii, 1998, Issue:6

    Topics: Acid-Base Equilibrium; Antibiotic Prophylaxis; Bronchitis; Bronchodilator Agents; Histamine Antagoni

1998
Changes in theophylline clearance during acute illness.
    JAMA, 1978, Oct-20, Volume: 240, Issue:17

    Topics: Acute Disease; Aged; Airway Obstruction; Female; Heart Failure; Humans; Male; Metabolic Clearance Ra

1978
Theophylline disposition in acutely ill hospitalized patients. The effect of smoking, heart failure, severe airway obstruction, and pneumonia.
    The American review of respiratory disease, 1978, Volume: 118, Issue:2

    Topics: Acute Disease; Adult; Aged; Airway Obstruction; Asthma; Bronchitis; Chronic Disease; Female; Half-Li

1978
[A case of galactorrhea in a patient treated with theophylline].
    Revista clinica espanola, 1992, Volume: 190, Issue:1

    Topics: Adult; Female; Galactorrhea; Humans; Pneumonia; Theophylline

1992
Ofloxacin in lower respiratory tract infections.
    Infection, 1991, Volume: 19 Suppl 7

    Topics: Bacterial Infections; Bronchitis; Chronic Disease; Cross Infection; Drug Administration Schedule; Dr

1991
Theophylline inhibition of BCG-induced pulmonary inflammatory responses.
    Annals of allergy, 1990, Volume: 64, Issue:6

    Topics: Animals; BCG Vaccine; Bronchoalveolar Lavage Fluid; Lung; Male; Pneumonia; Rats; Rats, Inbred Strain

1990
Trichosporon beigelii pneumonia in a neutropenic patient.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1989, Volume: 8, Issue:7

    Topics: Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Humans; Lung Diseases, Fungal; Mal

1989
Enoxacin in the treatment of lower respiratory tract infections.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21 Suppl B

    Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Bronchiectasis; Bronchitis; Chronic Disease; Drug

1988
[What is certain in the therapy of unspecific lung diseases?].
    Der Internist, 1969, Volume: 10, Issue:12

    Topics: Anti-Bacterial Agents; Asthma; Bronchiectasis; Empyema; Humans; Lung Abscess; Lung Diseases; Lung Di

1969
[Diaphylline in the combined treatment of pneumonia in children].
    Pediatriia akusherstvo i ginekologiia, 1968, Volume: 1

    Topics: Humans; Infant; Pneumonia; Theophylline

1968
An effective oral medication for long term bronchodilation.
    Annals of allergy, 1965, Volume: 23, Issue:9

    Topics: Adult; Asthma; Bronchitis; Humans; Middle Aged; Pneumonia; Pulmonary Emphysema; Theophylline

1965