theophylline has been researched along with Obstructive Lung Diseases in 613 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The sputum pharmacokinetics and clinical efficacy of ciprofloxacin in lower respiratory tract infections is reviewed." | 10.16 | Clinical efficacy of ciprofloxacin in lower respiratory tract infections. ( Pedersen, SS, 1989) |
| "One of the important modes of action of theophylline in asthma and chronic obstructive airway disease may be the inhibition of airway inflammation." | 10.16 | The effects of theophylline on airway inflammation. ( Pauwels, R, 1987) |
| "A randomized trial of long-acting theophylline drugs theopek taken twice daily and euphilong taken in a single daily dose has been performed in 59 elderly patients suffering from bronchial asthma, chronic obstructive bronchitis." | 9.07 | [The comparative efficacy of the prolonged-action theophylline preparations Theopek and Euphylong in elderly patients with chronic obstructive lung diseases]. ( Belousov, IuB; Nonikov, VE; Salikova, VV, 1993) |
| "We compared the frequency and severity of cardiac arrhythmias during combined oral theophylline and inhaled salbutamol vs." | 9.06 | Theophylline and salbutamol in combination in patients with obstructive pulmonary disease and concurrent heart disease: effect on cardiac arrhythmias. ( Huikuri, H; Korhonen, UR; Linnaluoto, M; Poukkula, A, 1989) |
| "This study sought answers to 2 questions: (1) Is severe dyspnea to the point of exhaustion regularly accompanied by diaphragmatic fatigue in patients with moderately severe chronic obstructive pulmonary disease (COPD)? (2) When diaphragmatic fatigue occurs in such patients, does theophylline prevent or delay its onset? Eight eucapnic patients with moderately severe COPD were subjected to 2 different stresses to the point of severe dyspnea requiring cessation of the stress." | 9.06 | Dyspnea and diaphragmatic fatigue in patients with chronic obstructive pulmonary disease. Responses to theophylline. ( Druz, WS; Kongragunta, VR; Sharp, JT, 1988) |
| "Dyspnea is influenced by both physiologic and psychologic factors." | 7.76 | The role of theophylline in the treatment of dyspnea in COPD. ( Mahler, DA, 1987) |
| "To evaluate the potential inhibitory effect of theophylline on the pulmonary oxidative stress in asthma and chronic obstructive pulmonary disease (COPD), we concomitantly measured the blood levels of theophylline, a non-selective phosphodiesterase (PDE) inhibitor and lipid peroxides as an index of oxidative stress." | 7.70 | Evidence of oxidative stress in asthma and COPD: potential inhibitory effect of theophylline. ( Dobashi, K; Hisada, T; Iizuka, K; Ishizuka, T; Iwamae, S; Mori, M; Shimizu, Y; Tsukagoshi, H, 2000) |
| "Theophylline may have a beneficial effect in treatment and prevention of erythrocytosis in patients with COPD." | 7.69 | Effect of theophylline on erythrocytosis in chronic obstructive pulmonary disease. ( Beeri, M; Hubert, A; Kramer, MR; Matzner, Y; Oren, R, 1997) |
| "Troleandomycin has been reported to be useful for reducing the steroid requirement of patients with asthma." | 7.68 | Use of troleandomycin as a steroid-sparing agent in both asthma and chronic obstructive pulmonary disease. ( Cash, M; Shivaram, U, 1991) |
| "Plasma theophylline levels (mcg/ml) of 93 patients with a bronchopulmonary disease (asthma and chronic obstructive lung disease) who were on theophylline (normal or retarded) treatment, were determined on admission at the emergency ward because of acute bronchospasm." | 7.67 | [Levels of blood theophylline in patients with acute bronchospasm]. ( García Delgado, R; García Morillas, M; Martínez, B; Martínez, MJ; Puche, E; Saucedo, R, 1989) |
| "Sixteen patients with multifocal atrial tachycardia (MAT) who were taking theophylline were identified over 6 months." | 7.67 | Multifocal atrial tachycardia: a toxic effect of theophylline. ( Guarnieri, T; Levine, JH; Michael, JR, 1985) |
| "The pharmacokinetics of theophylline was investigated in five hyperthyroid, five hypothyroid, and five euthyroid patients, all with chronic obstructive pulmonary disease." | 7.67 | Pharmacokinetics of theophylline in hyperthyroid and hypothyroid patients with chronic obstructive pulmonary disease. ( Pokrajac, M; Simić, D; Varagić, VM, 1987) |
| "A 70-year-old patient who developed ventricular tachycardia (up to several hundreds of consecutive ventricular complexes) in the presence of theophylline intoxication (29 micrograms/ml) is reported." | 7.67 | Prolonged runs of ventricular tachycardia as a complication of theophylline intoxication. Report of a case. ( Parizel, G; Siemons, LJ, 1986) |
| "The concentrations of theophylline, terbutaline and salbutamol in post-mortem blood samples from 68 patients (17-85 years old) with asthma or chronic obstructive lung disease, 54 of whom had died of asthma, were analysed." | 7.67 | Post-mortem concentrations of salbutamol, terbutaline and theophylline in asthma patients. ( Boman, G; Lindsjö, M; Lindström, B; Strandberg, K; Wiholm, BE, 1987) |
| "The kinetics and the effects on the ventilatory function peak expiratory flow rate (PEFR) of a single 600-mg oral dose of theophylline were investigated in 46 adult patients with bronchial asthma (BA) and in 16 adult patients with chronic airflow obstruction (CAO)." | 7.66 | Theophylline kinetics and ventilatory flow in bronchial asthma and chronic airflow obstruction: influence of erythromycin. ( Bah, H; Duroux, P; Giudicelli, JF; Mathieu, M; Richer, C; Thuillez, C, 1982) |
| " It is concluded that both drugs can be administered concomitantly without any dosage adjustment of theophylline." | 6.67 | Clinical pharmacokinetics of theophylline during co-treatment with ticarcillin plus clavulanic acid in patients suffering from acute exacerbation of chronic bronchitis. ( Cazzola, M; Lampa, E; Matera, MG; Paizis, G; Rossi, F; Santangelo, G; Vinciguerra, A, 1993) |
| "Long-term ambulatory Holter-monitoring was used to evaluate the arrhythmogenic effects of beta 2-agonist therapy, alone and in combination with a xanthine derivative, theophylline or enprofylline." | 6.66 | Cardiac arrhythmias in patients with mild-to-moderate obstructive lung disease. Comparison of beta-agonist therapy alone and in combination with a xanthine derivative, enprofylline or theophylline. ( Conradson, TB; Eklundh, G; Olofsson, B; Pahlm, O; Persson, G, 1985) |
| "Dyspnea was rated using 2 clinical indexes based on 3 components affecting breathlessness: functional impairment, magnitude of task that evokes dyspnea, and the associated magnitude of effort." | 6.66 | Sustained-release theophylline reduces dyspnea in nonreversible obstructive airway disease. ( Loke, J; Mahler, DA; Matthay, RA; Snyder, PE; Wells, CK, 1985) |
| "Theophylline's role in the treatment of airway obstruction has been challenged, yet it remains a useful agent in the management of obstructive lung disease." | 6.38 | Theophylline in asthma and COPD: changing perspectives and controversies. ( Poe, RH; Utell, MJ, 1991) |
| "Host factors play an important role in the dosing requirements of theophylline." | 6.37 | Effect of disease states on theophylline elimination. ( Jenne, JW, 1986) |
| "Theophylline has been utilized widely as a bronchodilator, but only in recent years have its positive cardiovascular effects been recognized in patients with chronic obstructive pulmonary disease." | 6.37 | Theophylline improves global cardiac function and reduces dyspnea in chronic obstructive lung disease. ( Mahler, DA; Matthay, RA, 1986) |
| "The sputum pharmacokinetics and clinical efficacy of ciprofloxacin in lower respiratory tract infections is reviewed." | 6.16 | Clinical efficacy of ciprofloxacin in lower respiratory tract infections. ( Pedersen, SS, 1989) |
| "One of the important modes of action of theophylline in asthma and chronic obstructive airway disease may be the inhibition of airway inflammation." | 6.16 | The effects of theophylline on airway inflammation. ( Pauwels, R, 1987) |
| "Theophylline is known to increase the risk of epileptic seizures and might have a role in seizure-induced brain damage." | 5.37 | Selective bilateral hippocampal lesions after theophylline-induced status epilepticus causes a permanent amnesic syndrome. ( Bogdahn, U; Kohl, Z; Lürding, R; Schröder, M; Schuierer, G; Uyanik, G; Weidner, N, 2011) |
| " On the other day, the patients received sustained-release theophylline, 200 mg twice a day, or in a dosage taken previously to achieve a serum theophylline level of 55 to 110 mumol/L." | 5.28 | The effects of inhaled albuterol and oral theophylline on gastroesophageal reflux in patients with gastroesophageal reflux disease and obstructive lung disease. ( Austin, J; Rohwedder, JJ; Ruzkowski, CJ; Sanowski, RA; Waring, JP, 1992) |
| "Theophylline was found to increase hemoglobin saturation and decrease carbon dioxide pressures without significant effects on the overall efficiency of pulmonary gas exchange." | 5.28 | [Effects of theophylline on the course of hypercapnic respiratory insufficiency]. ( Bevignani, G; Chiappini, F; Fresu, R, 1990) |
| "A study was carried out in 30 patients with chronic obstructive pulmonary disease to compare the effectiveness and tolerance of a standard theophylline preparation given 4-times daily with that of a long-acting preparation given in comparable dosage twice daily." | 5.27 | Short-acting versus a long-acting preparation of theophylline ('Xantivent') in the treatment of reversible bronchospasm. ( Andrasch, R; Schmitz-Schumann, M, 1984) |
| " The patient later developed pneumonia and was enrolled in a study of nosocomial acquired pneumonia involving clinafloxacin versus ceftazidime." | 5.08 | Clinafloxacin-theophylline drug interaction. ( Matuschka, PR; Vissing, RS, 1995) |
| " Altogether, 2772 serum theophylline concentrations were obtained from 131 normal subjects and 306 patients suffering from chronic asthma or chronic obstructive pulmonary disease who participated in the phase I, II, and III clinical trials in Japan." | 5.08 | Population pharmacokinetics of theophylline. III. Premarketing study for a once-daily administered preparation. ( Hori, R; Iwai, T; Iwakawa, S; Komada, F; Maekawa, H; Okumura, K; Shimizu, T; Tanigawara, Y, 1995) |
| "A randomized trial of long-acting theophylline drugs theopek taken twice daily and euphilong taken in a single daily dose has been performed in 59 elderly patients suffering from bronchial asthma, chronic obstructive bronchitis." | 5.07 | [The comparative efficacy of the prolonged-action theophylline preparations Theopek and Euphylong in elderly patients with chronic obstructive lung diseases]. ( Belousov, IuB; Nonikov, VE; Salikova, VV, 1993) |
| "The therapeutic value of a sustained-release theophylline preparation (Theospirex retard 300 mg) with administration of the daily dose once a day in the evening compared to the 2 x 1 dosage usual was investigated in 19 patients suffering from asthma symptoms manifested mainly at night." | 5.07 | [Comparison of two long-acting theophylline preparations in daily evening administration]. ( Holzer, R, 1993) |
| "To examine the mechanisms through which two bronchodilators (theophylline and salbutamol) influence dyspnea during daily activities." | 5.07 | Mechanism of bronchodilator effect in chronic airflow limitation. ( Guyatt, GH; Jaeschke, R; Keller, J; Newhouse, MT; Singer, J, 1991) |
| "The clinical effectiveness and the pharmacokinetic parameters of a once-a-day sustained release preparation of anhydrous theophylline were studied in a trial carried out on 10 adult patients affected by bronchial asthma or chronic obstructive lung disease." | 5.06 | [Clinico-laboratory evaluation a new sustained-release preparation of anhydrous theophylline]. ( Aiolfi, S; Capellini, G; Gandola, L; Ghio, L; Mauri, F; Patrini, G; Scartabellati, A; Soccini, F, 1989) |
| "We compared the frequency and severity of cardiac arrhythmias during combined oral theophylline and inhaled salbutamol vs." | 5.06 | Theophylline and salbutamol in combination in patients with obstructive pulmonary disease and concurrent heart disease: effect on cardiac arrhythmias. ( Huikuri, H; Korhonen, UR; Linnaluoto, M; Poukkula, A, 1989) |
| "Theophylline plasma levels and FEV1 were measured in patients affected by chronic obstructive pulmonary disease and a concomitant disease state (congestive heart failure, chronic cor pulmonale, obesity, peptic disease, hepatic cirrhosis, chronic renal failure) and treated with a sustained release theophylline preparation." | 5.06 | Effect of various disease states on theophylline plasma levels and on pulmonary function in patients with chronic airway obstruction treated with a sustained release theophylline preparation. ( Dal Negro, R; Monici-Preti, P; Pomari, C; Turco, P, 1987) |
| "Sixteen patients with asthma and/or chronic obstructive lung disease were treated for 8 days by scored tablets of sustained-release theophylline." | 5.06 | [Prescription of Theostat 300 as a single evening dose]. ( Bida, C; Germouty, J; Moreau, L, 1987) |
| "This study sought answers to 2 questions: (1) Is severe dyspnea to the point of exhaustion regularly accompanied by diaphragmatic fatigue in patients with moderately severe chronic obstructive pulmonary disease (COPD)? (2) When diaphragmatic fatigue occurs in such patients, does theophylline prevent or delay its onset? Eight eucapnic patients with moderately severe COPD were subjected to 2 different stresses to the point of severe dyspnea requiring cessation of the stress." | 5.06 | Dyspnea and diaphragmatic fatigue in patients with chronic obstructive pulmonary disease. Responses to theophylline. ( Druz, WS; Kongragunta, VR; Sharp, JT, 1988) |
| "In a double-blind study we compared the effect of 2 mg ketotifen (Zaditen) daily and 1050 mg aminophylline daily for 6 months in two groups of altogether 24 patients with bronchial asthma and a chronic obstruction of the airways." | 5.05 | The influence of ketotifen and aminophylline on the central and peripheral airways. ( Dorow, P; Schiess, W, 1983) |
| "The therapeutic value of 80 micrograms atropine methonitrate delivered per metered aerosol and its combination with 450 micrograms reproterol was investigated in a controlled double-blind cross-over trial in 17 patients with chronic bronchitis and airway obstruction." | 5.05 | Comparative studies of atropine methonitrate and its combination with reproterol in chronic airway obstruction. ( Aurich, R; Macha, HN, 1982) |
| ": reproterol (Bronchospasmin), terbutalin (Bricanyl) and fenoterol (Berotec) were examined in a randomized study in 90 patients." | 5.05 | [Postoperative respiratory therapy: bronchospasmolytic activity and side-effects of some recently introduced beta-sympatheticomimetic agents (author's transl)]. ( Beer, S; Brandl, M; Hamer, P, 1981) |
| "Initial responses and changes in baseline after two-week treatments with a sustained release ephedrine-theophylline-phenobarbital (ETP) tablet and terbutaline tablets were studied in a double-blind crossover trial for 20 patients with chronic obstructive lung diseases." | 5.04 | The cardiorespiratory effects of oral terbutaline and an ephedrine-theophylline-phenobarbital combination: comparison in patients with chronic obstructive ventilatory disorders. ( Cohen, BM, 1978) |
| "The acute bronchodilator effect of the beta 2-adrenoceptor agonist terbutaline was tested single-blind cross-over in out-patients with chronic obstructive airways disease (intrinsic asthma)." | 5.04 | [Lung function studies with the bronchodilator terbutaline]. ( Bonelli, J; Hitzenberger, G; Kaik, G; Laggner, A; Magometschnigg, D, 1979) |
| " Caffeine is used to treat apnea of the newborn because of its low toxicity." | 4.80 | Standards of laboratory practice: theophylline and caffeine monitoring. National Academy of Clinical Biochemistry. ( Kotagal, U; Pesce, AJ; Rashkin, M, 1998) |
| "Theophylline has emerged as a major prophylactic agent for controlling the symptoms of chronic asthma, but it provides little if any relief of pulmonary symptoms caused by irreversible chronic airways obstruction." | 4.77 | Update on the pharmacodynamics and pharmacokinetics of theophylline. ( Hendeles, L; Massanari, M; Weinberger, M, 1985) |
| " The suggestion is made that failure to recognize the nonlinearity of the dose-response curves for bronchodilators has resulted in underestimating their combined action." | 3.76 | Theophylline as a bronchodilator in COPD and its combination with inhaled beta-adrenergic drugs. ( Jenne, JW, 1987) |
| "Dyspnea is influenced by both physiologic and psychologic factors." | 3.76 | The role of theophylline in the treatment of dyspnea in COPD. ( Mahler, DA, 1987) |
| "Theophylline can increase the transepithelial secretion of fluid into the respiratory tract lumen by stimulating the chloride pump which is controlled by cyclic AMP." | 3.76 | Theophylline and mucociliary clearance. ( Ziment, I, 1987) |
| "To evaluate the potential inhibitory effect of theophylline on the pulmonary oxidative stress in asthma and chronic obstructive pulmonary disease (COPD), we concomitantly measured the blood levels of theophylline, a non-selective phosphodiesterase (PDE) inhibitor and lipid peroxides as an index of oxidative stress." | 3.70 | Evidence of oxidative stress in asthma and COPD: potential inhibitory effect of theophylline. ( Dobashi, K; Hisada, T; Iizuka, K; Ishizuka, T; Iwamae, S; Mori, M; Shimizu, Y; Tsukagoshi, H, 2000) |
| "Theophylline is widely used by patients with asthma and chronic obstructive pulmonary disease as a bronchodilator." | 3.69 | [Is routine monitoring of theophylline blood levels really effective?]. ( Atsmon, J; Dolev, E; Priel, IE, 1995) |
| "The practicality, efficacy, and tolerance of a standardized, ready-to-use theophylline solution (Eloasthmin, Leopold Pharma, Graz) was studied on 33 patients with bronchial asthma and/or chronic obstructive bronchitis (COPD) (19 males, 14 females) aged 19 to 79 (median 50) years." | 3.69 | [Practicability, effectiveness and tolerance of a standardized prepared theophylline infusion]. ( Aigner, K; Kummer, F; Lorber, H; Pfeiffer, KP; Pohl, WR; Würtz, J, 1996) |
| "Theophylline may have a beneficial effect in treatment and prevention of erythrocytosis in patients with COPD." | 3.69 | Effect of theophylline on erythrocytosis in chronic obstructive pulmonary disease. ( Beeri, M; Hubert, A; Kramer, MR; Matzner, Y; Oren, R, 1997) |
| "Initiating a course of electroconvulsive therapy (ECT) in patients taking theophylline has been associated with status epilepticus and consequent brain damage or even death." | 3.68 | Electroconvulsive therapy in patients taking theophylline. ( Rasmussen, KG; Zorumski, CF, 1993) |
| "4 mg/kg as an intravenous infusion over 5 min (a dosage previously used to test drug interactions with cimetidine and ranitidine) were evaluated in 7 patients with chronic obstructive pulmonary disease (COPD) and peptic ulcer disease before and after 8 days' treatment with famotidine 40mg at night." | 3.68 | Famotidine and theophylline pharmacokinetics. An unexpected cimetidine-like interaction in patients with chronic obstructive pulmonary disease. ( Dal Negro, R; Pomari, C; Turco, P, 1993) |
| "Troleandomycin has been reported to be useful for reducing the steroid requirement of patients with asthma." | 3.68 | Use of troleandomycin as a steroid-sparing agent in both asthma and chronic obstructive pulmonary disease. ( Cash, M; Shivaram, U, 1991) |
| " The possibility of using saliva and urine was investigated and evaluated in theophylline (Th) therapy, both in asthmatic children and adults." | 3.68 | When is the use of alternative biological fluid in pharmacokinetics possible; an example of theophylline. ( Agbaba, D; Miljkovic, B; Pokrajac, M; Varagic, VM, 1991) |
| " Urinary excretion of 3-methylhistidine (3-MH) as an index of myofibrillar protein catabolism was measured at the end of a 7-day treatment period with theophylline and a 5-day basal untreated control period in eight patients with stable chronic obstructive pulmonary disease (COPD), eight patients with stable asthma, and eight normal healthy volunteers." | 3.68 | Effect of theophylline on urinary excretion of 3-methylhistidine in patients with lung disease. ( Hoppel, CL; McFadden, ER; Wei, IW, 1991) |
| "to determine the relation of serum theophylline concentrations (STC) to the occurrence of cardiac arrhythmias in a population of hospitalized patients." | 3.68 | The arrhythmogenicity of theophylline. A multivariate analysis of clinical determinants. ( Bittar, G; Friedman, HS, 1991) |
| "Two aged patients with bronchial asthma and chronic obstructive pulmonary disease who suffered convulsions that resulted in permanent brain damage during treatment with the recommended therapeutic dose of theophylline are presented here." | 3.68 | Permanent brain damage possibly caused by theophylline in two elderly patients with airway obstruction. ( Aikawa, T; Fukushima, T; Itabashi, S; Sasaki, H; Sekizawa, K; Yanai, M, 1990) |
| "The efficacy of microcrystalline theophylline is examined in patients with stabilized bronchial asthma." | 3.67 | [Possibilities for optimizing therapy with theophylline preparations. Clinical effectiveness and side effects of microcrystalline theophylline]. ( Iwainsky, H; Sehrt, I; Wiesner, B, 1984) |
| "To determine whether asthma alone can cause irreversible airflow obstruction 42 men and 47 women with chronic asthma (mean duration 22 (SD 13) years) without evidence of other disease likely to cause irreversible airflow obstruction were treated with theophylline orally and a beta agonist both orally and by inhalation for four weeks." | 3.67 | Asthma and irreversible airflow obstruction. ( Brown, PJ; Finucane, KE; Greville, HW, 1984) |
| "In the treatment of obstructive lung diseases theophylline is one of the most important drugs." | 3.67 | [Possibilities for optimizing therapy with theophylline preparations. I. On the pharmacokinetics of theophylline preparations]. ( Iwainsky, H; Sehrt, I; Wiesner, B, 1984) |
| "Theophylline has long been a cornerstone of bronchodilator therapy for asthma and chronic obstructive lung disease, but until recently its use carried the risk of serious, even fatal, toxicity." | 3.67 | Theophylline therapy. Titrating dosage requirements. ( Uden, DL; Wyatt, RA; Zaske, DE, 1984) |
| "Plasma theophylline levels (mcg/ml) of 93 patients with a bronchopulmonary disease (asthma and chronic obstructive lung disease) who were on theophylline (normal or retarded) treatment, were determined on admission at the emergency ward because of acute bronchospasm." | 3.67 | [Levels of blood theophylline in patients with acute bronchospasm]. ( García Delgado, R; García Morillas, M; Martínez, B; Martínez, MJ; Puche, E; Saucedo, R, 1989) |
| "Sixteen patients with multifocal atrial tachycardia (MAT) who were taking theophylline were identified over 6 months." | 3.67 | Multifocal atrial tachycardia: a toxic effect of theophylline. ( Guarnieri, T; Levine, JH; Michael, JR, 1985) |
| "The pharmacokinetics of theophylline was investigated in five hyperthyroid, five hypothyroid, and five euthyroid patients, all with chronic obstructive pulmonary disease." | 3.67 | Pharmacokinetics of theophylline in hyperthyroid and hypothyroid patients with chronic obstructive pulmonary disease. ( Pokrajac, M; Simić, D; Varagić, VM, 1987) |
| "A 70-year-old patient who developed ventricular tachycardia (up to several hundreds of consecutive ventricular complexes) in the presence of theophylline intoxication (29 micrograms/ml) is reported." | 3.67 | Prolonged runs of ventricular tachycardia as a complication of theophylline intoxication. Report of a case. ( Parizel, G; Siemons, LJ, 1986) |
| "The concentrations of theophylline, terbutaline and salbutamol in post-mortem blood samples from 68 patients (17-85 years old) with asthma or chronic obstructive lung disease, 54 of whom had died of asthma, were analysed." | 3.67 | Post-mortem concentrations of salbutamol, terbutaline and theophylline in asthma patients. ( Boman, G; Lindsjö, M; Lindström, B; Strandberg, K; Wiholm, BE, 1987) |
| "In a hypothyroid patient who suffered also from chronic obstructive lung disease and mild congestive heart failure, treatment with 1 g/day theophylline administered orally, was followed by a life-threatening theophylline intoxication manifested by repeated epileptic fits and ventricular fibrillation, successfully reverted to sinus rhythm." | 3.66 | Life-threatening theophylline intoxication in a hypothyroid patient. ( Aderka, D; Garfinkel, D; Gitter, S; Pinkhas, J; Santo, M; Shavit, G, 1983) |
| "The kinetics and the effects on the ventilatory function peak expiratory flow rate (PEFR) of a single 600-mg oral dose of theophylline were investigated in 46 adult patients with bronchial asthma (BA) and in 16 adult patients with chronic airflow obstruction (CAO)." | 3.66 | Theophylline kinetics and ventilatory flow in bronchial asthma and chronic airflow obstruction: influence of erythromycin. ( Bah, H; Duroux, P; Giudicelli, JF; Mathieu, M; Richer, C; Thuillez, C, 1982) |
| "Drug therapy of asthma in the elderly with sympathomimetics, theophylline, steroids, and mucokinetic agents is described, with discussion of dosage evaluation, toxicity, possible drug interactions, and suggested management of common problems." | 3.66 | Management of respiratory problems in the aged. ( Ziment, I, 1982) |
| "18 elderly patients (17 male and 1 female) with chronic obstructive pulmonary disease, and 2 elderly patients (1 male, 1 female) with an acute asthmatic attack were treated with theophylline." | 3.66 | Maintenance oral theophylline therapy: suggested schedule in elderly patients. ( Alroy, G; Krivoy, N, 1980) |
| " clearance estimation methods were evaluated n 19 chronic obstructive pulmonary disease (COPD)/asthmatic patients who were receiving aminophylline by continuous infusion." | 3.66 | Evaluation of two methods for estimating theophylline clearance prior to achieving steady state. ( Anderson, G; Edwards, WD; Hook, E; Koup, J; Resman, B; Slaughter, R, 1981) |
| "Mechanics of breathing, gas exchange and pulmonary hemodynamics were investigated in 10 patients with chronic-obstructive lung diseases before and after treatment with oral doses of 160 mg 3'-chloro-2'-(N-methyl-N-[(morpholino-carbonyl)methyl]-aminomethyl)benzanilide hydrochloride (fominoben, Noleptan) and 300 mg oxyethyltheophylline given three times daily." | 3.66 | [The effect of fominoben and oxyethyltheophylline in combination on pulmonary function and pulmonary hemodynamics in chronic-obstructive diseases of the airways (author's transl)]. ( Siemon, G; Thoma, R, 1978) |
| "Theophylline has been shown to have corticosteroid-sparing effects for the treatment of human asthma." | 2.72 | Theophylline does not potentiate the effects of a low dose of dexamethasone in horses with recurrent airway obstruction. ( Cesarini, C; Hamilton, E; Lavoie, JP; Picandet, V, 2006) |
| " Any adverse event occurring during the treatment period was recorded on a diary card." | 2.70 | Efficacy and safety of oxitropium bromide, theophylline and their combination in COPD patients: a double-blind, randomized, multicentre study (BREATH Trial). ( Bellia, V; Bensi, G; Bianco, S; Foresi, A; Grassi, V; Olivieri, D; Volonté, M, 2002) |
| " At each visit, a dose-response curve to inhaled salbutamol was constructed using a total cumulative dose of 800 microg." | 2.69 | Additive effects of salmeterol and fluticasone or theophylline in COPD. ( Calderaro, F; Cazzola, M; Centanni, S; Di Lorenzo, G; Di Perna, F; Testi, R, 2000) |
| "Theophylline was infused after the 17th dose of each treatment." | 2.68 | Controlled study of the putative interaction between famotidine and theophylline in patients with chronic obstructive pulmonary disease. ( Bachmann, K; Jauregui, L; King, JD; Miller, K; Reese, JH; Schwartz, J; Scott, M; Stepanavage, M; Sullivan, TJ; Yeh, KC, 1995) |
| " When nefazodone and theophylline were co-administered, theophylline pharmacokinetic parameters did not significantly differ from those obtained when theophylline was administered with placebo." | 2.68 | Lack of an effect of nefazodone on the pharmacokinetics and pharmacodynamics of theophylline during concurrent administration in patients with chronic obstructive pulmonary disease. ( Barbhaiya, RH; Dockens, RC; Greene, DS; Rapoport, D; Roberts, D, 1995) |
| " And then, with double-blind crossover in design, twice-daily theophylline doseing (TD) or once-daily theophylline dosing (OD) was given in a randomly assigned sequence, and serum theophylline concentration (STC) was measured, and other physiological testings were similar as baseline measurements." | 2.68 | [Effects of theophylline on lung function and sleep in patients with severe chronic obstructive pulmonary disease]. ( Li, Y; Liu, Y, 1997) |
| "Oral theophylline treatment causes a sustained increase in resting oxygen consumption and heart rate but does not modify the metabolic response to acutely inhaled salbutamol." | 2.67 | Effect of oral theophylline on resting energy expenditure in normal volunteers. ( Agrawal, A; Dash, A; Moxham, J; Ponte, J; Venkat, N, 1994) |
| " An one-compartment open pharmacokinetic model with first-order absorption and first-order elimination was used." | 2.67 | [Evaluation of theophylline population pharmacokinetics in adult hospitalized patients using NONMEM analysis]. ( Chen, G; Li, Z, 1994) |
| " Control of theophylline dosage using measured theophylline concentrations and evaluation of efficacy and toxicity was performed under double-blind conditions." | 2.67 | Theophylline target concentration in severe airways obstruction - 10 or 20 mg/L? A randomised concentration-controlled trial. ( Black, P; Briant, R; Couch, R; Holford, N; Kennedy, J, 1993) |
| "Theophylline is a well known bronchodilator which has been used for more than 50 years in the treatment of obstructive pulmonary diseases." | 2.67 | Effect of theophylline on exercise performance in patients with severe chronic obstructive pulmonary disease. ( Fink, G; Gabbay, U; Kaye, C; Spitzer, SA; Sulkes, J, 1994) |
| " It is concluded that both drugs can be administered concomitantly without any dosage adjustment of theophylline." | 2.67 | Clinical pharmacokinetics of theophylline during co-treatment with ticarcillin plus clavulanic acid in patients suffering from acute exacerbation of chronic bronchitis. ( Cazzola, M; Lampa, E; Matera, MG; Paizis, G; Rossi, F; Santangelo, G; Vinciguerra, A, 1993) |
| " This study shows that the additive bronchodilating effect of theophylline, when used in combination with salbutamol, 200 micrograms, and ipratropium, 40 micrograms, is significant but small in stable COPD." | 2.67 | Is oral theophylline effective in combination with both inhaled anticholinergic agent and inhaled beta 2-agonist in the treatment of stable COPD? ( Ikeda, A; Izumi, T; Koyama, H; Nishimura, K, 1993) |
| "Theophylline therapy was continued in 20 patients and replaced by placebo from day 3 on in the remainder; measurements were repeated on days 5 and 6." | 2.67 | Effects of theophylline withdrawal in severe chronic obstructive pulmonary disease. ( Jörres, RA; Kirsten, DK; Magnussen, H; Wegner, RE, 1993) |
| "Theophylline treatment with sustained steady state concentrations about 17 mg/l provides worthwhile objective and subjective further benefits for patients handicapped by chronic obstructive lung disease when it is added to bronchodilators and corticosteroids." | 2.67 | Value of theophylline treatment in patients handicapped by chronic obstructive lung disease. ( Addis, GJ; Howie, CA; McKay, SE; Thomson, AH; Whiting, B, 1993) |
| "This study was undertaken to determine if a computerized pharmacokinetic program for adjusting theophylline infusion rates could attain a goal serum theophylline level more accurately than physician-derived adjustments and what clinical impact this would have." | 2.67 | A randomized controlled trial of computerized pharmacokinetic theophylline dosing versus empiric physician dosing. ( Casner, PR; Ho, H; Reilly, R, 1993) |
| "Theophylline levels were median 10." | 2.67 | Effect of therapeutic theophylline levels on the sleep quality and daytime cognitive performance of normal subjects. ( Boellert, F; Deary, IJ; Douglas, NJ; Engleman, HM; Fitzpatrick, MF; McHardy, R; Shapiro, CM, 1992) |
| " Euphylong showed a bioavailability of 83%, the maximum of the serum level was attained at night." | 2.67 | [Euphylong in standard dosage: comparison with an international retard preparation for twice-daily administration in recommended dosage]. ( Huber, W; Maier-Stocker, P; Siemon, G, 1991) |
| " The results of the presented multicenter study with Euphylong therefore confirm the pharmacokinetic and clinical data gained from single center studies with small patient numbers hitherto." | 2.67 | [Multicenter study with a large number of patients for the validation of pharmacokinetic and clinical findings from controlled studies with small patient cohorts]. ( Götz, JK; Sauter, R, 1991) |
| " From this study, we conclude that once daily theophylline dosing with Uni-Dur compared with bid or tid dosing with Theo-Dur produces similar theophylline levels and pulmonary function, and most COPD patients who are taking 400 to 900 mg Theo-Dur daily can be managed with 800 mg Uni-Dur once daily at bedtime." | 2.67 | Conversion of COPD patients from multiple to single dose theophylline. Serum levels and symptom comparison. ( Chetty, KG; Despars, JA; Giron, A; Light, RW, 1991) |
| "To further understand the therapeutic action of theophylline, we investigated, in a randomized double-blind crossover study, the effects of a 4-day treatment with two different dosage regimens of theophylline on the circadian rhythm of cortisol plasma concentrations in seven COPD patients." | 2.67 | Effect of theophylline on cortisol plasma concentrations in patients with chronic obstructive pulmonary disease. ( Gimeno, F; Jonkman, JH; Steenhuis, EJ, 1990) |
| "The predictability and intraindividual variability of serum theophylline concentrations (STC) after different dosing schedules were investigated in 24 patients with chronic obstructive lung disease (COLD)." | 2.67 | Predictability and intraindividual variability of serum theophylline concentrations in patients with obstructive lung disease: 12-h versus 24-h dosing. ( Follath, F; Keller, B; Perruchoud, A; Schmidlin, O; Vozeh, S, 1990) |
| " Home monitoring prevented unnecessary clinic visits in several instances when theophylline dosage adjustments were based on telephone reports from patients." | 2.67 | Home monitoring of theophylline levels: a novel therapeutic approach. ( Chandler, MH; Clifton, GD; Coons, SJ; Foster, TS; Louis, BA; Phillips, BA, 1990) |
| "Theophylline was administered in identical doses, except that the final dosage increase was not made if plasma theophylline was 12 mg/ml or higher." | 2.67 | A comparison of enprofylline and theophylline in the maintenance therapy of chronic reversible obstructive airway disease. ( Abboud, RT; Boucher, S; Chapman, KR; Day, A; Hodder, RV; Hyland, RH; Kreisman, H; Peters, S; Rivington, R; York, EL, 1990) |
| "Doxofylline was better tolerated than theophylline considering either the number of unwanted side-effects: (doxofylline 12; theophylline 37) or number of drop-outs due to side-effects (doxofylline 5; theophylline 10)." | 2.66 | Treatment of reversible chronic airways obstruction with doxofylline compared with slow-release theophylline: a double-blind, randomized, multicentre trial. ( Balzano, G; Campisi, V; Capone, M; De Felice, A; Di Filippo, A; Foddai, G; Franzone, JS; Grossi, E; Jodice, F; Melillo, G, 1989) |
| "With disulfiram pretreatment, the plasma clearance of theophylline was decreased from 105." | 2.66 | Dose-dependent inhibition of theophylline metabolism by disulfiram in recovering alcoholics. ( Bush, ED; Costello, P; Day, JD; Dewey, LV; Jue, SG; Loi, CM; Vestal, RE, 1989) |
| " Special attention was paid to circadian rhythms in pharmacokinetics and pharmacodynamic effects, during 24 h of measuring." | 2.66 | Chronopharmacodynamics and kinetics after symmetric and asymmetric multiple theophylline doses in patients with chronic obstructive pulmonary disease. ( Berg, WC; Gimeno, F; Jonkman, JH; Steenhuis, EJ; van Veenen, R; Weibel, MA, 1989) |
| "Long-term ambulatory Holter-monitoring was used to evaluate the arrhythmogenic effects of beta 2-agonist therapy, alone and in combination with a xanthine derivative, theophylline or enprofylline." | 2.66 | Cardiac arrhythmias in patients with mild-to-moderate obstructive lung disease. Comparison of beta-agonist therapy alone and in combination with a xanthine derivative, enprofylline or theophylline. ( Conradson, TB; Eklundh, G; Olofsson, B; Pahlm, O; Persson, G, 1985) |
| " These data suggest that an unequal twice daily sustained-release theophylline dosing with higher dose in the evening may be beneficial in the treatment of chronic obstructive lung disease." | 2.66 | [Time-related distribution of delayed-action theophylline in the treatment of chronic obstructive bronchopneumopathies]. ( Arnaud, A; Bruguerolle, B; Parrel, M; Philip-Joet, F; Vestri, R, 1988) |
| " To assess the safety and efficacy of Uniphyl tablets, an oral theophylline preparation formulated for once-daily dosing, in elderly patients with chronic airflow obstruction, we conducted a randomized, three-phase, double-blind crossover study comparing evening dosing with Uniphyl tablets, Theo-Dur tablets administered twice daily, and placebo." | 2.66 | Safety and efficacy of once-daily Uniphyl tablets compared with twice-daily Theo-Dur tablets in elderly patients with chronic airflow obstruction. ( Aitken, TL; Calcutt, L; Hodder, RV; Rivington, RN; Stewart, JH, 1988) |
| "Our study evaluated whether a dose-response relationship exists for theophylline and diaphragmatic contractility within the usual therapeutic range for theophylline." | 2.66 | Theophylline and diaphragmatic contractility. Investigation of a dose-response relationship. ( Cuddy, PG; Emory, CE; Foxworth, JW; Knudson, SM; Pyszczynski, DR; Reisz, GR, 1988) |
| "Patients able to produce consistent results on testing of respiratory function spent two weeks having dosage of theophylline adjusted to give individual pharmacokinetic data." | 2.66 | Dose response relation to oral theophylline in severe chronic obstructive airways disease. ( Chrystyn, H; Mulley, BA; Peake, MD, 1988) |
| "When theophylline was withdrawn, all parameters were significantly worsened, but after reinstitution of treatment they all improved significantly." | 2.66 | Effects of withdrawal of sustained-release theophylline in patients with chronic obstructive lung disease. ( Aamodt, T; Dahle, R; Horgen, O, 1988) |
| " These findings suggest that an unequal, twice-daily SRT dosing with the greater amount of drug at night may be beneficial in the treatment of COPD." | 2.66 | Unequal twice-daily, sustained-release theophylline dosing in chronic obstructive pulmonary disease. ( Arnaud, A; Bruguerolle, B; Parrel, M; Philip-Joet, F, 1987) |
| " The pharmacokinetics and the bronchodilating effect of theophylline were studied during 1 week of morning dosing and 1 week of evening dosing in a randomized cross-over design in thirteen patients with reversible airways obstruction, treated with a new 'once-a-day' theophylline capsule formulation." | 2.66 | The effect of dosing time on the pharmacokinetics and pharmacodynamics of a 'once-a-day' sustained release theophylline preparation. ( Lamont, H; Pauwels, R; Van der Straeten, M, 1987) |
| "Theophylline as a single treatment caused significant changes in none of the test variables, though favorable trends were observed." | 2.66 | Efficacy of inhaled metaproterenol and orally-administered theophylline in patients with chronic airflow obstruction. ( Dullinger, D; Kronenberg, R; Niewoehner, DE, 1986) |
| "Aminophylline was administered intravenously as a bolus and an infusion for 150 minutes." | 2.66 | The hemodynamic effects of aminophylline and salbutamol alone and in combination. ( Burgess, CD; Crane, J; Graham, AN; Maling, TJ, 1986) |
| "Theophylline plasma levels and profiles were evaluated in patients with chronic obstructive pulmonary disease during once-daily dosing of an ultrasustained-release theophylline preparation (Theo-1; capsules filled with microgranules containing 400 mg anhydrous theophylline)." | 2.66 | Once-daily dosing of a new ultrasustained-release theophylline preparation. ( Demedts, M; Nys, J; Tjandramaga, TB; Van den Brande, P; Verhelst, F, 1987) |
| " Values for elimination half-life (7." | 2.66 | Theophylline clearance in patients with severe chronic obstructive pulmonary disease receiving supplemental oxygen and the effect of acute hypoxemia. ( Charan, NB; Crowley, JJ; Cusack, BJ; Mercer, GD; Vestal, RE, 1986) |
| " The tested medication has a favorable therapeutic spectrum as a result of the low dosage of the individual substances." | 2.66 | [Bronchospasmolytic effectiveness of controlled drug combinations]. ( Forche, G; Harnoncourt, K; Zenker, G, 1986) |
| "Theophylline or placebo was then administered every 12 hours with crossover after 6 weeks." | 2.66 | Long-term therapy with sustained-release theophylline. ( Arnulf, V; Myhre, KI; Walstad, RA, 1985) |
| " These results suggest a better bioavailability of Th, likely accounted for by a more advanced pharmaceutical technology." | 2.66 | Serum theophylline and ventilatory function in chronic obstructive lung disease. Comparison between two slow-release formulations of theophylline. ( Cornelli, U; Grassi, V; Sorbini, CA; Tantucci, C; Verdecchia, P, 1985) |
| "Dyspnea was rated using 2 clinical indexes based on 3 components affecting breathlessness: functional impairment, magnitude of task that evokes dyspnea, and the associated magnitude of effort." | 2.66 | Sustained-release theophylline reduces dyspnea in nonreversible obstructive airway disease. ( Loke, J; Mahler, DA; Matthay, RA; Snyder, PE; Wells, CK, 1985) |
| "The bioavailability profiles of two sustained-release oral theophylline preparations, Respbid and Theo-Dur, were compared in 19 adults with obstructive airways disease." | 2.66 | Comparison of two sustained-release theophylline preparations in adult patients with obstructive airways disease. ( Allen, WT; Conlon, PF; Harkaway, PS; Hirsh, JD, 1985) |
| " Neither at the low nor at the high dosage (2 +/- 4 mg/kg), giving plasma concentrations of 8." | 2.65 | Effects of enprofylline, a xanthine lacking adenosine receptor antagonism, in patients with chronic obstructive lung disease. ( Andersson, KE; Lunell, E; Persson, CG; Svedmyr, N, 1982) |
| " The graduation of the film tablet allows individualized dosage without losing the sustained release action by slowly increasing the theophylline-serum-level during a dosage interval of 12 hours." | 2.65 | [Treatment of chronic obstructive respiratory disease with a new purified theophylline preparation in delayed-action form]. ( Kaik, G, 1984) |
| "Theophylline serum levels were measured by radioimmunoassay." | 2.65 | [Therapy of obstructive respiratory tract diseases with pure theophylline retard]. ( Arens, PJ, 1982) |
| "Aminophylline (0,24 g i." | 2.64 | [(Whole body plethysmographic studies on the bronchospasmolytic effect of injectabls drugs. Comparison of aminophylline, diprophylline and hexoprenaline)]. ( Kaik, G, 1976) |
| "Theophylline has been used in the treatment of obstructive pulmonary diseases since 30s." | 2.41 | [Theophylline--contemporary views on cellular mechanism of action]. ( Chorostowska-Wynimko, J, 2000) |
| "The type of arrhythmias found may be supraventricular (premature atrial beats, paroxysmal supraventricular tachycardia, multifocal atrial tachycardia, atrial flutter, atrial fibrillation) or ventricular (premature ventricular beats, sustained ventricular tachycardia, torsades de pointes, ventricular fibrillation) that may lead to sudden cardiac death." | 2.40 | [Evaluation of hyperkinetic cardiac arrhythmia in chronic obstructive bronchopneumopathy]. ( Conte, G; Lauro, S; Lazzarin, M; Perrone, A; Rigon, N, 1997) |
| "Theophylline, a drug that has been used for several decades, has several different actions at a cellular level, including inhibition of phosphodiesterase isoenzymes, antagonism of adenosine, enhancement of catecholamine secretion, and modulation of calcium fluxes." | 2.40 | Theophylline: recent advances in the understanding of its mode of action and uses in clinical practice. ( Lipsky, JJ; Vassallo, R, 1998) |
| "Therefore, smoking cessation is the most important therapeutic approach." | 2.40 | [Etiology, diagnosis and therapy of COPD]. ( Perruchoud, AP; Solèr, M; Ullmer, E, 1999) |
| "Theophylline's role in the treatment of airway obstruction has been challenged, yet it remains a useful agent in the management of obstructive lung disease." | 2.38 | Theophylline in asthma and COPD: changing perspectives and controversies. ( Poe, RH; Utell, MJ, 1991) |
| "Theophylline is a second-line drug for the symptomatic treatment of obstructive pulmonary diseases." | 2.38 | Management of chronic airway obstruction: theophylline--is it still necessary? ( Sybrecht, GW; Ukena, D, 1990) |
| " When chronic symptoms necessitate maintenance treatment, the frequency of dosing may become a deciding factor in the selection of a bronchodilator." | 2.37 | Tulobuterol in the management of obstructive airways disease in adults. ( Patel, KR, 1985) |
| " Oral therapy should begin at low doses in stable patients to avoid side effects, and dosing should take into account the many factors, such as age, cardiovascular and liver function, smoking status, and possible drug interactions, that can affect theophylline metabolism." | 2.37 | The use of theophylline in 'irreversible' chronic obstructive pulmonary disease. An update. ( Hill, NS, 1988) |
| "Theophylline has been utilized widely as a bronchodilator." | 2.37 | Favorable cardiovascular effects of theophylline in COPD. ( Matthay, RA, 1987) |
| "With the introduction of sustained-release theophylline formulations for once-daily dosing or for unequally divided twice-daily dosing, comparison with conventional equally divided twice-daily dosing has been focused on nocturnal serum theophylline concentrations (STCs), plateau properties and peak-trough fluctuation." | 2.37 | Theophylline steady-state pharmacokinetics: recent concepts and their application in chronotherapy of reactive airway diseases. ( Beier, W; Johnson, E; Steinijans, VW; Trautmann, H, 1987) |
| "Host factors play an important role in the dosing requirements of theophylline." | 2.37 | Effect of disease states on theophylline elimination. ( Jenne, JW, 1986) |
| "Theophylline has been utilized widely as a bronchodilator, but only in recent years have its positive cardiovascular effects been recognized in patients with chronic obstructive pulmonary disease." | 2.37 | Theophylline improves global cardiac function and reduces dyspnea in chronic obstructive lung disease. ( Mahler, DA; Matthay, RA, 1986) |
| "Theophylline is a widely used bronchodilator, but only recently have its positive cardiovascular actions been recognized in patients with chronic obstructive pulmonary disease (COPD)." | 2.37 | Effects of theophylline on cardiovascular performance in chronic obstructive pulmonary disease. ( Matthay, RA, 1985) |
| "Theophylline is known to increase the risk of epileptic seizures and might have a role in seizure-induced brain damage." | 1.37 | Selective bilateral hippocampal lesions after theophylline-induced status epilepticus causes a permanent amnesic syndrome. ( Bogdahn, U; Kohl, Z; Lürding, R; Schröder, M; Schuierer, G; Uyanik, G; Weidner, N, 2011) |
| "Theophylline was the main drug prescribed to in-patients discharged from hospital, although inhaling beta 2-agonists were also recommended in few cases." | 1.30 | [Respiratory medicine in the aged. Therapeutic problemsd]. ( Cossi, S; De Martinis, M; Ghisla, MK; Grassi, V; Leonardi, R; Tomasi, MF, 1997) |
| " This observation further nourishes previous hypotheses that chronic administration of an A1-receptor antagonist leads to up-regulation of the adenosine receptor number." | 1.30 | Adenosine is worth trying in patients with paroxysmal supraventricular tachycardia on chronic theophylline medication. ( Aul, C; Giagounidis, AA; Klein, RM; Schäfer, S; Strauer, BE, 1998) |
| " The one-compartment model as a pharmacokinetic model was assumed." | 1.30 | [Population pharmacokinetic analysis of theophylline: relationship between serum concentrations and clinical effects in therapeutic drug monitoring]. ( Fukuoka, M; Goshima, T; Matsumoto, M; Matsumoto, Y; Matsuzaki, T; Noguchi, S; Tanikawa, K, 1999) |
| "Theophylline treatment resulted in a significant increase in REE by 15%." | 1.30 | Increased resting energy expenditure is related to plasma TNF-alpha concentration in stable COPD patients. ( Beaufrère, B; Beaujon, G; Bedu, M; Caillaud, D; Coudert, J; Nguyen, LT; Ritz, P; Vasson, M, 1999) |
| "Treatment with theophylline requires monitoring of dosage, preferably by determining the theophylline content in whole blood or serum, because theophylline pharmaco kinetics is most variable and therefore difficult to define, and because of possible interactions with other drugs." | 1.29 | [Drug monitoring: theophylline--comparison of 3 methods for determination]. ( Göbel, D; Kropp, R, 1995) |
| "Mixed atrial and ventricular arrhythmias, which are rarely mentioned as a specific feature of theophylline intoxication, were found in 16% of our patients and accounted for 29% of the cardiovascular manifestations." | 1.29 | The clinical implication of theophylline intoxication in the Emergency Department. ( Chern, TL; Deng, JF; Hu, SC; Lee, CH; Tsai, J; Wang, RB, 1994) |
| "Steady-state theophylline pharmacokinetic parameters were studied in a panel of 14 patients with chronic obstructive pulmonary disease (COPD)." | 1.29 | Steady-state pharmacokinetics of theophylline in COPD patients treated with dirithromycin. ( Bachmann, K; Jauregui, L; Sides, G; Sullivan, TJ, 1993) |
| "The effects and the mechanism of single and long-term administration of theophylline on ventilatory regulation were investigated in patients with chronic obstructive pulmonary disease (COPD)." | 1.29 | [Effects of theophylline on ventilatory regulation in patients with chronic obstructive pulmonary disease]. ( Aritomi, T; Ikeda, A; Ishibashi, M; Miyahara, S; Senju, S; Toyoshima, H; Watanabe, K; Yoshida, M, 1993) |
| " The results showed that after a different loading dosage of aminophylline (6 mg/kg, 5 mg/kg and 4 mg/kg) was administered by intravenous injection, mPAP in the 6 mg/kg group was decreased more significantly (P less than 0." | 1.28 | [Relationship among dosages of aminophylline, plasma levels of theophylline and variation of pulmonary arterial pressure]. ( Chen, W; Liu, S; Luo, Y; Yuan, Y, 1992) |
| " On the other day, the patients received sustained-release theophylline, 200 mg twice a day, or in a dosage taken previously to achieve a serum theophylline level of 55 to 110 mumol/L." | 1.28 | The effects of inhaled albuterol and oral theophylline on gastroesophageal reflux in patients with gastroesophageal reflux disease and obstructive lung disease. ( Austin, J; Rohwedder, JJ; Ruzkowski, CJ; Sanowski, RA; Waring, JP, 1992) |
| "The influence of usual regimens of the H2 blocking drugs, cimetidine, ranitidine, and nizatidine on the steady-state plasma concentrations and pharmacokinetic characteristics of theophylline was studied in seventeen patients with chronic obstructive pulmonary disease (COPD)." | 1.28 | Comparative investigation of the influence of nizatidine, ranitidine, and cimetidine on the steady-state pharmacokinetics of theophylline in COPD patients. ( Bachmann, K; Jauregui, L; Levine, L; Martin, M; Mauro, LS; Sullivan, TJ, 1992) |
| "Rokitamycin is a new 16-membered macrolide antibiotic." | 1.28 | Impact of rokitamycin, a new 16-membered macrolide, on serum theophylline. ( Cazzola, M; Matera, MG; Paternò, E; Rossi, F; Santangelo, G; Scaglione, F, 1991) |
| " Although the number of subjects studied is small, our data suggest that air-driven nebulised high-dose salbutamol may be safe in the treatment of severe chronic obstructive airway disease but when combined with oral theophylline, a significant fall in plasma potassium may occur." | 1.28 | Air-driven nebulised high-dose salbutamol in severe chronic obstructive airways disease: is it safe? ( Friend, JA; Lai, CK; Legge, JS, 1991) |
| " Fluctuation at single dosage was 82 +/- 9% and at twice daily dosage 44 +/- 10%." | 1.28 | [Euphylong in patients with chronic obstructive airway diseases]. ( Kublik, A; von Wichert, P, 1991) |
| "The predicted steady-state serum theophylline concentration was calculated from the dosage rate divided by the predicted clearance to determine how many elevated concentrations (greater than 20 mg/L) were predictable." | 1.28 | A prospective evaluation of elevated serum theophylline concentrations to determine if high concentrations are predictable. ( Cranberg, JA; Ganz, MA; Greenberger, PA; Hubler, GL, 1991) |
| " It was concluded that both drugs could be administered concomitantly without any dosage adjustment of theophylline." | 1.28 | Influence of sulbactam plus ampicillin on theophylline clearance. ( Caputi, M; Cazzola, M; Girbino, G; Guidetti, E; Mattina, R; Santangelo, G, 1991) |
| " Pharmacokinetic parameters were calculated according to the concentration of theophylline in the sera of patients in the second group." | 1.28 | [Effect of ranitidine on the pharmacokinetics of theophylline in patients with obstructive pulmonary disease]. ( Bojović, I; Bozović, M; Despotović, N; Dmitrović, V; Milovanović, M; Paranos, S; Vidanović, M, 1991) |
| "Theophylline was given as a single evening dose." | 1.28 | Individualization of theophylline dosage: a Bayesian method evaluated in patients with once-daily dosing. ( Martz, W; Oellerich, M; Schnabel, D; Sybrecht, GW, 1991) |
| " This regimen is now indicated for morning and evening dosing for reversible airway obstruction, in the United States and Canada, and marks the first available treatment for these diseases to include dosing time in the therapeutic strategy." | 1.28 | Chronotherapy of reversible airways disease with once-daily evening doses of a controlled-release theophylline preparation. ( Goldenheim, PD; Schein, LK, 1991) |
| "Theophylline was found to increase hemoglobin saturation and decrease carbon dioxide pressures without significant effects on the overall efficiency of pulmonary gas exchange." | 1.28 | [Effects of theophylline on the course of hypercapnic respiratory insufficiency]. ( Bevignani, G; Chiappini, F; Fresu, R, 1990) |
| " The mean elimination half-life was 14 +/- 7 hours." | 1.28 | Pharmacokinetic study of controlled-release choline theophyllinate in elderly patients. ( Beck, PR; Clarke, I; Gregory, J; le Cotonnec, JY; Mondal, BK, 1990) |
| "A single dose, single point method of predicting patients' oral maintenance theophylline dosage has been compared with a noninvasive method." | 1.28 | A single oral dose method for predicting steady state theophylline concentrations in clinical practice. ( Cole, RB; Fitzpatrick, RW; Jones, PW; Mann, JS; Mucklow, JC; Prowse, K, 1990) |
| " Theophylline elimination half-life rose from 8." | 1.28 | Impairment of theophylline clearance by a hypocaloric low-protein diet in chronic obstructive pulmonary disease. ( Fisher, M; Hughes, RL; Juan, D; Shin, SG, 1990) |
| "Seven patients had new supraventricular arrhythmias with levels of 21 to 40 micrograms/mL." | 1.28 | Risk of toxicity in patients with elevated theophylline levels. ( Connors, AF; Devlin, C; Emerman, CL, 1990) |
| "Theophylline blood level was tested on the first day and once steady state had been achieved, and was always within the therapeutic range." | 1.28 | [Clinical functional study of a new delayed-action preparation of "once a day" anhydrous theophylline in patients with chronic obstructive bronchopneumopathy]. ( Bruzzoni, A; Gatto, PG; Valenti, V, 1989) |
| " Theophylline toxicity in this patient might have been induced by chronic administration of isoniazid." | 1.28 | Theophylline-isoniazid interaction. ( Cabezas, R; Izquierdo, I; Jané, F; Torrent, J, 1989) |
| " These data show that in case of single daily theophylline administration an high dosage is necessary to maintain the drug concentration within the range of therapeutic levels." | 1.28 | Comparative dose study of a theophylline sustained-release tablet formulation after repeated administrations. ( Bonfardeci, G; Cova, D; Cuglituri, G; Rossini, L, 1989) |
| " Cimetidine significantly reduced theophylline clearance, but increased its half-life and the area under the curve (AUC) (p less than 0." | 1.27 | Pharmacokinetics of theophylline and the H2-antagonist drugs cimetidine and ranitidine. ( Carloni, C; Dal Negro, R; Pomari, C; Trevisan, F; Turco, P; Zoccatelli, O, 1984) |
| "A study was carried out in 30 patients with chronic obstructive pulmonary disease to compare the effectiveness and tolerance of a standard theophylline preparation given 4-times daily with that of a long-acting preparation given in comparable dosage twice daily." | 1.27 | Short-acting versus a long-acting preparation of theophylline ('Xantivent') in the treatment of reversible bronchospasm. ( Andrasch, R; Schmitz-Schumann, M, 1984) |
| "Cimetidine was given to some patients in both groups after steady state for theophylline was achieved." | 1.27 | The influence of orally administered cimetidine and theophylline on the elimination of each drug in patients with chronic airways obstruction. ( Garton, A; Herbert, FA; Hsu, K; Legatt, D; Sproule, BJ; Tam, YK, 1984) |
| " Only 1 of the 21 patients met the criteria for dose dependency of a greater than or equal to 50% reduction in clearance with dosage increase." | 1.27 | Dose-dependent kinetics of theophylline in adults with pulmonary diseases. ( Gotz, VP; Massey, KL; Russell, WL, 1984) |
| " These results do not support recent recommendations to monitor serum theophylline concentrations or reduce theophylline dosage during the 48-hour period following influenza vaccination." | 1.27 | Influenza vaccination and theophylline pharmacokinetics in patients with chronic obstructive lung disease. ( Hashisaki, PA; Stults, BM, 1983) |
| "Because theophylline (T) has a narrow therapeutic index, serum concentrations resulting from previous outpatient therapy must be considered when planning intravenous (IV) aminophylline dosage in the emergency department (ED)." | 1.27 | Prediction of serum theophylline levels. ( Elenbaas, RM; Payne, VW, 1984) |
| " Thus non-compliance with prescribed theophylline dosage occurred in 26 (41." | 1.27 | Patient compliance with oral theophylline therapy. ( Kinney, CD; McDevitt, DG; Taylor, DR, 1984) |
| " Prescribers should be aware of this potential interaction and reduce theophylline dosage where appropriate." | 1.27 | Cimetidine-theophylline interaction in patients with chronic obstructive airways disease. ( Grice, J; McGuffie, C; Roberts, RK, 1984) |
| " Increasing the dosage up to 15 mg per kg of body weight a day while theophylline determinations are pending appears to be safe in this group of patients." | 1.27 | Outpatient theophylline determinations. ( Beekman, JF; Covelli, HD; Knodel, AR, 1984) |
| "Circadian variation in plasma theophylline concentrations was studied in eight patients with obstructive airways disease during regular 12-hourly dosing at 09." | 1.27 | Circadian variation in plasma theophylline concentrations during maintenance therapy with a sustained-release preparation in patients with obstructive airways disease. ( Duffin, D; Kinney, CD; McDevitt, DG; Taylor, DR, 1984) |
| "05), half-life increased 48% (6." | 1.27 | Cimetidine inhibits theophylline clearance in patients with chronic obstructive pulmonary disease: a study using stable isotope methodology during multiple oral dose administration. ( Mercer, GD; Musser, B; Thummel, KE; Vestal, RE, 1983) |
| "Treatment with aminophylline, according to the nomogram published by Jusko and coworkers, was monitored in 13 patients suffering from acute exacerbations of COPD." | 1.27 | Monitoring aminophylline therapy using Jusko's dosage guidelines. ( Alférez, NP; Calandre, EP; Mata, GV; Morales, AM; Moreno, E; Perez de la Cruz, AJ, 1983) |
| " Because of the serious side effects of steroids, however, objective evidence of improvement must be documented before long-term use can be justified." | 1.27 | Chronic airflow obstruction. Two-pronged approach to outpatient management. ( Hale, KA, 1983) |
| "Oral theophylline was given to 6 adults with airways obstruction." | 1.27 | Lack of dose dependent kinetics of theophylline. ( Brown, PJ; Dusci, LJ; Shenfield, GM, 1983) |
| " Whereas aminophylline in therapeutic dosage failed to provoke VE in arrhythmia-free COPD patients, the effect of aminophylline on pre-existent VE is variable." | 1.27 | The effect of aminophylline on cardiac rhythm in advanced chronic obstructive pulmonary disease: correlation with serum theophylline levels. ( Au, WY; de Soyza, ND; Dutt, AK; Hargis, JL; Tuck, RL, 1983) |
| " For 75% of the male and 85% of the female patients a single evening dosage was sufficient." | 1.27 | [Tolerance of a new oral long-acting theophylline in patients with obstructive airway diseases]. ( Dusik, B; Nolte, D, 1983) |
| "The effects of split virus influenza vaccine on the pharmacokinetics of theophylline and the in vivo and in vitro induction of interferon were studied in 23 volunteers." | 1.27 | The effect of split virus influenza vaccination on theophylline pharmacokinetics. ( Bertino, JS; Grabowski, N; May, JJ; Pratt, DS; Richtsmeier, WJ, 1985) |
| " Bedtime dosing may prevent nocturnal shortness of breath." | 1.27 | Pharmacologic approaches to obstructive airway disease. ( Beck, BW, 1985) |
| "The therapy of pulmonary hypertension is difficult in those diseases where the causes or mechanisms are not understood or are unknown." | 1.27 | Treatment of pulmonary hypertension. ( Denolin, H; Mathey, DG, 1986) |
| " Percent changes in venous pCO2 and pO2 were used as parameters of the pharmacodynamic action." | 1.27 | [Pharmacokinetics and pharmacodynamics of theophylline in geriatric patients with multiple diseases]. ( Bauer, M; Mühlberg, W; Platt, D; Salzner, U, 1987) |
| "Non-compliance to dosage regimes is an important clinical problem with severe repercussions for the management of chronic illnesses requiring continued treatment." | 1.27 | TDM of theophylline--compliance evaluation. ( Barrueco, M; Dominguez-Gil, A; Garcia, MJ; Martin, A; Otero, MJ, 1988) |
| "Enoxacin is a safe and effective alternative to parenteral treatment of lower respiratory tract infections." | 1.27 | Enoxacin in the treatment of lower respiratory tract infections. ( Arnaud, A; Frances, Y; Nourrit, J; Philip-Joet, F, 1988) |
| "Verapamil hydrochloride was added to each theophylline solution to produce final verapamil concentrations of 0." | 1.27 | Compatibility of premixed theophylline and verapamil intravenous admixtures. ( Aviles, AI; Johnson, CE; Lloyd, CW; Rybarz, KL, 1988) |
| "Theophylline serum levels were measured in 34 adult patients suffering from chronic obstructive pulmonary disease." | 1.27 | Recommended standard theophylline doses are inadequate in chronic obstructive pulmonary disease. ( Savage, J; Wiseman, IC, 1987) |
| " The pharmacokinetic parameters of theophylline did not change during co-administration of ofloxacin and nalidixic acid." | 1.27 | The influence of quinolone derivatives on theophylline clearance. ( van Herwaarden, CL; Vree, TB; Wijnands, WJ, 1986) |
| " The ratio, (FEV1:FVC) X 100, was calculated for each patient before and after steady-state serum level determination and dosage adjustment." | 1.27 | Using a hand-held spirometer as a monitoring tool in chronic theophylline therapy. ( Catania, PN; Mikhail, MN, 1987) |
| " In contrast, on oral dosing a smaller area under the serum concentration-time curve was found during the night time (22." | 1.27 | Circadian changes in the absorption and elimination of theophylline in patients with bronchial obstruction. ( Follath, F; Uematsu, T; Vozeh, S, 1986) |
| "Theophylline is a commonly used bronchodilator in the treatment of chronic obstructive airways disease (COAD) with a narrow therapeutic range of 10 to 20 micrograms/ml." | 1.27 | Evaluation of tetracycline on theophylline disposition in patients with chronic obstructive airways disease. ( Gotz, VP; Ryerson, GG, 1986) |
| "To evaluate empiric dosing guidelines for aminophylline and phenytoin in the management of acute exacerbations of obstructive lung disease and seizure disorders, we utilized an emergency department (ED)-based EMIT system to measure stat plasma theophylline and phenytoin levels in patients intended to receive these drugs." | 1.27 | Effect of empiric dosing on blood levels of theophylline and phenytoin. ( Bederka, J; Curtis, RA; Hutchinson, RA; Troyer, WG, 1985) |
| " These results indicate that this simple method of Chiou may offer a reliable rapid estimation of total body clearance for dosage individualization in patients receiving intravenous aminophylline infusion." | 1.27 | Rapid estimation of total body clearance of theophylline in patients receiving intravenous aminophylline infusion. ( Al-Bazzaz, FJ; Chiou, WL; Lam, G; Lau, AH; Lui, CY; O'Connor, T, 1986) |
| " It is concluded that (1) theophylline dosage based entirely on standard dose will lead to an unacceptably high percentage of under-dosing; (2) schematic consideration of body-weight, sex, age, living habits, and accompanying diseases proved to be unreliable and insufficient for individual dose determination; (3) dose adaptation to individual clinical situations and serum concentration is necessary in theophylline treatment of ambulatory patients and, in the light of present technical facilities, is cost-effective." | 1.27 | [Determination of serum theophylline concentration in ambulatory practice]. ( Neiss, A; Rietbrock, N; Staib, AH, 1985) |
| " In patients receiving theophylline, blood levels should be monitored closely and dosage adjusted if rifampicin therapy is introduced or withdrawn." | 1.27 | Effect of rifampicin administration on theophylline pharmacokinetics in humans. ( Gray, BJ; Jamieson, AP; Moxham, J; Powell-Jackson, PR; Williams, R, 1985) |
| "Although arrhythmias associated with myocardial infarction are managed primarily with drug therapy, those associated with acute respiratory failure respond best to adequate oxygenation and correction of metabolic and hemodynamic abnormalities." | 1.27 | Managing asthma and COPD in patients with cardiovascular disease. ( George, RB; Payne, DK, 1985) |
| "Arrhythmia recurrence appeared to be dependent on reaching a critical but "nontoxic" serum theophylline concentration in the presence of high normal levels of digoxin." | 1.27 | Atrial arrhythmias exacerbated by theophylline. Response to verapamil and evidence for triggered activity in man. ( Marchlinski, FE; Miller, JM, 1985) |
| " The drug was given orally in a dosage of 100 mg BID for ten days." | 1.27 | Therapeutic activity of ambroxol theophyllinacetate in chronic obstructive pulmonary diseases. ( Primbs, K, 1985) |
| "Theophylline is a medium-potency bronchodilator that is useful in the treatment of reversible airway obstruction from any cause." | 1.27 | Methylxanthine therapy and reversible airway obstruction. ( McFadden, ER, 1985) |
| " The appropriateness of ordering the serum theophylline determinations was evaluated on the basis of criteria including sampling at steady-state concentrations and sampling in proper relationship to the dosage schedule to represent a peak or trough concentration." | 1.26 | Evaluation of the ordering of serum theophylline concentrations. ( Gentry, SM; Goetter, WE; Keith, TD; McMillan, DM, 1981) |
| "The present study is a prospective evaluation of a dosing nomogram for oral theophylline in 69 middle-aged and elderly patients (mean age 58." | 1.26 | Individualization of oral theophylline dosage in elderly patients. ( Boye, NP; Bredesen, JE; Kornstad, S; Talseth, T, 1981) |
| "Reproterol is a monomulecolar combination of catecholamine and theophilline." | 1.26 | [The hemodynamic effects of reproterol in patients with chronic obstructive lung disease (author's transl)]. ( Bonaduce, D; Canonico, V; Cocozza, M; Ferrara, N; Petretta, M; Rengo, F; Romano, E, 1981) |
| " The dosage of beta 2-mimetics and especially glucocorticoids could be reduced." | 1.26 | [Long-term therapy with a peroral effective theophyllin compound (author's transl)]. ( Pertusini, B; Zwick, H, 1980) |
| "Proxyphylline serum levels were estimated in parallel repeatedly." | 1.26 | [Effectiveness of proxyphylline in chronic obstructive pulmonary disease (author's transl)]. ( Förster, OB; Geisler, LS; Rohner, HG; Thiel, H, 1980) |
| " The half-life of absorption was 19 +/- 9 min (mean +/- SD)." | 1.26 | Disposition and clinical pharmacokinetics of microcrystalline theophylline. ( Berg, WC; de Zeeuw, RA; Greving, JE; Jonkman, JH; Orie, NG; Schoenmaker, R, 1980) |
| " There was no correlation between dosage and serum theophylline level." | 1.26 | Serum level monitoring of a new slow release theophylline formulation in patients with chronic lung disease. ( Butcher, MA; Klumpp, JA; Marlin, GE; Thompson, PJ, 1980) |
| " When initiating continuous oral aminophylline therapy, dosage guidelines, based on the mean ATC calculated for each group, were predicted, and trough theophylline serum levels of 10mug/ml were obtained." | 1.26 | Oral aminophylline therapy. Increased dosage requirements in children. ( Austrian, S; Johnson, PB; Miller, KW; Strem, EL; Zaske, DE, 1977) |
| " This plateau can be maintained and is dependent upon dosage and the half-life of theophylline, which varies amongst individuals." | 1.26 | [Theophylline blood levels after administration of Euphyllin retard (author's transl)]. ( Ahrens, J, 1977) |
| " Thus, use of saliva theophylline measurements obtained by the Schack and Waxler method to adjust dosage regimens cannot be recommended in these patients." | 1.26 | Unpredictability of theophylline saliva measurements in chronic obstructive pulmonary disease. ( Bighley, L; Burkey, S; Hendeles, L; Richardson, R, 1977) |
| " Fourteen patients (30%) had a toxic reaction to theophylline." | 1.26 | Clinical experience with theophylline. Relarionships between dosage, serum concentration, and toxicity. ( Jacobs, MH; Kessler, G; Senior, RM, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 366 (59.71) | 18.7374 |
| 1990's | 221 (36.05) | 18.2507 |
| 2000's | 25 (4.08) | 29.6817 |
| 2010's | 1 (0.16) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kohl, Z | 1 |
| Uyanik, G | 1 |
| Lürding, R | 1 |
| Schuierer, G | 1 |
| Bogdahn, U | 1 |
| Schröder, M | 1 |
| Weidner, N | 1 |
| Bellia, V | 1 |
| Foresi, A | 1 |
| Bianco, S | 1 |
| Grassi, V | 5 |
| Olivieri, D | 1 |
| Bensi, G | 1 |
| Volonté, M | 1 |
| KOCHSIEK, K | 1 |
| NELLE, K | 1 |
| Cesarini, C | 1 |
| Hamilton, E | 1 |
| Picandet, V | 1 |
| Lavoie, JP | 1 |
| Pozzi, E | 1 |
| Perruchoud, A | 2 |
| Schwartz, AM | 1 |
| Bauman, JH | 1 |
| Kimelblatt, BJ | 1 |
| Caraccio, TR | 1 |
| Silverman, HM | 1 |
| Simon, GI | 1 |
| Beck, GJ | 1 |
| McDonald, GJ | 1 |
| Hudson, LD | 2 |
| Medici, TC | 2 |
| Ramer, P | 1 |
| Hatt, RR | 1 |
| Unger, S | 1 |
| Matthay, RA | 11 |
| Berger, HJ | 4 |
| Van Nierop, JC | 1 |
| Bukowskyj, M | 2 |
| Nakatsu, K | 2 |
| Munt, PW | 2 |
| Niewoehner, DE | 6 |
| Leatherman, JW | 2 |
| Citone, C | 1 |
| Carelli, M | 1 |
| Di Marcotullio, G | 1 |
| Tubaro, M | 1 |
| Milazzotto, F | 1 |
| Ahrens, J | 2 |
| Lunell, E | 1 |
| Svedmyr, N | 1 |
| Andersson, KE | 1 |
| Persson, CG | 1 |
| Kreukniet, J | 1 |
| Utama, I | 1 |
| Hamelink, ML | 1 |
| Dal Negro, R | 6 |
| Pomari, C | 6 |
| Zoccatelli, O | 1 |
| Trevisan, F | 3 |
| Carloni, C | 1 |
| Turco, P | 8 |
| Magnussen, H | 3 |
| Scheidt-Mackes, M | 1 |
| Thompson, PJ | 3 |
| Kemp, MW | 1 |
| McAllister, WA | 1 |
| Turner-Warwick, M | 1 |
| Aamodt, T | 2 |
| Lien, JT | 1 |
| Haaversen, O | 1 |
| Osmundsen, K | 1 |
| Passamonte, PM | 1 |
| Martinez, AJ | 1 |
| Alexander, MR | 6 |
| Taylor, JW | 1 |
| Dull, WL | 6 |
| Kasik, J | 1 |
| Mustion, AL | 1 |
| Gotz, VP | 3 |
| Dolly, FR | 1 |
| Block, AJ | 1 |
| Wiesner, B | 3 |
| Sehrt, I | 5 |
| Iwainsky, H | 5 |
| Nolte, D | 6 |
| Dusik, B | 2 |
| Ullah, MI | 1 |
| Munro, CS | 1 |
| Prowse, K | 2 |
| Prignot, J | 1 |
| Delaunois, L | 1 |
| Lulling, J | 1 |
| Delwiche, JP | 1 |
| Vandenplas, F | 1 |
| Kaik, G | 6 |
| Kaik, B | 1 |
| Andrasch, R | 1 |
| Schmitz-Schumann, M | 1 |
| Jenne, JW | 5 |
| Siever, JR | 1 |
| Druz, WS | 2 |
| Solano, JV | 1 |
| Cohen, SM | 1 |
| Sharp, JT | 3 |
| Silins, RA | 1 |
| Butcher, MA | 3 |
| Marlin, GE | 4 |
| Hsu, K | 1 |
| Garton, A | 1 |
| Sproule, BJ | 1 |
| Tam, YK | 1 |
| Legatt, D | 1 |
| Herbert, FA | 1 |
| Massey, KL | 1 |
| Russell, WL | 1 |
| Carlson, JA | 1 |
| Li, LS | 1 |
| Panuccio, P | 2 |
| Viroli, L | 1 |
| Chelucci, G | 1 |
| Cresci, F | 2 |
| Kasik, JE | 3 |
| Dal Negro, RW | 2 |
| Serra, R | 1 |
| Wiffen, JK | 1 |
| Jackson, SH | 1 |
| Taylor, DR | 6 |
| Kinney, CD | 5 |
| McDevitt, DG | 6 |
| Marvin, PM | 1 |
| Baker, BJ | 1 |
| Dutt, AK | 3 |
| Murphy, ML | 1 |
| Bone, RC | 1 |
| Kamat, SR | 2 |
| Hoskote, VR | 1 |
| Jagasia, RS | 2 |
| Shah, DC | 1 |
| Tyagi, NK | 1 |
| Stults, BM | 2 |
| Hashisaki, PA | 1 |
| Dorow, P | 3 |
| Schiess, W | 1 |
| Elenbaas, RM | 1 |
| Payne, VW | 1 |
| Roberts, RK | 1 |
| Grice, J | 1 |
| McGuffie, C | 1 |
| Brown, PJ | 2 |
| Greville, HW | 1 |
| Finucane, KE | 1 |
| Grützmacher, I | 1 |
| Schicht, R | 1 |
| Schlaeger, R | 1 |
| Sill, V | 1 |
| Courteheuse, C | 1 |
| Mountain, RD | 1 |
| Neff, TA | 1 |
| Fairshter, RD | 1 |
| Kandt, D | 4 |
| Wigle, R | 1 |
| Uden, DL | 1 |
| Wyatt, RA | 1 |
| Zaske, DE | 2 |
| Knodel, AR | 1 |
| Covelli, HD | 1 |
| Beekman, JF | 1 |
| Murciano, D | 2 |
| Aubier, M | 7 |
| Lecocguic, Y | 1 |
| Pariente, R | 2 |
| Ebden, P | 5 |
| Leopold, D | 2 |
| Smith, AP | 2 |
| Buss, D | 2 |
| Routledge, PA | 4 |
| Duffin, D | 1 |
| Sadoul, P | 2 |
| Woolson, RF | 1 |
| Macha, HN | 1 |
| Aurich, R | 1 |
| Arens, PJ | 1 |
| Eichhorn, J | 1 |
| Perré, R | 1 |
| Wemhöner, S | 2 |
| Oellerich, M | 6 |
| Sybrecht, G | 2 |
| Weinberger, M | 2 |
| Hendeles, L | 3 |
| Ahrens, R | 1 |
| Middleton, E | 1 |
| Aderka, D | 1 |
| Shavit, G | 1 |
| Garfinkel, D | 1 |
| Santo, M | 1 |
| Gitter, S | 1 |
| Pinkhas, J | 1 |
| Petty, TL | 1 |
| Vestal, RE | 4 |
| Thummel, KE | 2 |
| Musser, B | 2 |
| Mercer, GD | 3 |
| Calandre, EP | 2 |
| Perez de la Cruz, AJ | 1 |
| Morales, AM | 1 |
| Alférez, NP | 2 |
| Moreno, E | 1 |
| Mata, GV | 1 |
| Hale, KA | 1 |
| Ranke, C | 2 |
| Schmidt, G | 2 |
| Sybrecht, GW | 7 |
| Felice-Johnson, J | 1 |
| Higbee, MD | 1 |
| Hardigan, K | 1 |
| Green, JA | 1 |
| Clementi, WA | 1 |
| Dusci, LJ | 1 |
| Shenfield, GM | 1 |
| de Soyza, ND | 1 |
| Au, WY | 2 |
| Hargis, JL | 1 |
| Tuck, RL | 1 |
| Creutzig, H | 1 |
| Pierson, DJ | 1 |
| Stark, K | 1 |
| Hedgecock, M | 1 |
| Greening, AP | 1 |
| Baillie, E | 1 |
| Gribbin, HR | 1 |
| Pride, NB | 1 |
| Brandl, M | 1 |
| Beer, S | 1 |
| Hamer, P | 1 |
| Lamont, H | 2 |
| van der Straeten, M | 2 |
| Pauwels, R | 4 |
| Moerman, E | 1 |
| Bogaert, M | 1 |
| Pollert, I | 1 |
| Götz, M | 1 |
| Tanser, AR | 1 |
| Sierles, FS | 1 |
| Ossowski, MG | 1 |
| Richer, C | 1 |
| Mathieu, M | 1 |
| Bah, H | 1 |
| Thuillez, C | 1 |
| Duroux, P | 1 |
| Giudicelli, JF | 1 |
| Simmons, SM | 1 |
| Camp, RB | 1 |
| Mungall, DR | 1 |
| Bailey, WC | 1 |
| Schroers, M | 1 |
| Merbach, W | 1 |
| Don, M | 1 |
| Barclay, J | 1 |
| Whiting, B | 2 |
| Addis, GJ | 5 |
| Jue, SG | 2 |
| Howald, WN | 1 |
| Eaton, ML | 1 |
| MacDonald, FM | 1 |
| Church, TR | 1 |
| Ziment, I | 5 |
| Davies, R | 1 |
| Loke, J | 3 |
| Gottschalk, A | 2 |
| Zaret, BL | 2 |
| Ulmer, WT | 3 |
| Zimmermann, I | 1 |
| Durocher, A | 1 |
| L'Hopitault, JC | 1 |
| Chopin, C | 1 |
| Fourrier, F | 1 |
| Dubois, D | 1 |
| Wattel, F | 1 |
| Bracher, P | 1 |
| Brändli, O | 2 |
| Krivoy, N | 1 |
| Alroy, G | 1 |
| Lesko, LJ | 1 |
| Tabor, KJ | 1 |
| Johnson, BF | 1 |
| Dettmer, HH | 1 |
| Fenner, HG | 1 |
| Frazer, LA | 1 |
| Gentry, SM | 1 |
| Keith, TD | 1 |
| McMillan, DM | 1 |
| Goetter, WE | 1 |
| Ivainsky, H | 1 |
| Talseth, T | 2 |
| Kornstad, S | 1 |
| Boye, NP | 2 |
| Bredesen, JE | 2 |
| Anderson, G | 1 |
| Koup, J | 1 |
| Slaughter, R | 1 |
| Edwards, WD | 1 |
| Resman, B | 1 |
| Hook, E | 1 |
| Kongerud, J | 1 |
| Greger, G | 1 |
| Bonaduce, D | 1 |
| Ferrara, N | 1 |
| Canonico, V | 1 |
| Cocozza, M | 1 |
| Petretta, M | 1 |
| Romano, E | 1 |
| Rengo, F | 1 |
| Nahed, MR | 1 |
| Brossmann, D | 1 |
| Ruf, G | 1 |
| Wiessmann, KJ | 1 |
| Holmen, TL | 1 |
| Selvig, K | 1 |
| Bjerve, KS | 1 |
| Aas, K | 1 |
| Rugstad, HE | 1 |
| Lunde, PK | 1 |
| Lange-Nielsen, F | 1 |
| Brørs, O | 1 |
| Pertusini, B | 1 |
| Zwick, H | 1 |
| Geisler, LS | 2 |
| Thiel, H | 1 |
| Förster, OB | 1 |
| Rohner, HG | 1 |
| Jonkman, JH | 3 |
| Berg, WC | 2 |
| Schoenmaker, R | 1 |
| de Zeeuw, RA | 1 |
| Greving, JE | 1 |
| Orie, NG | 1 |
| Klumpp, JA | 1 |
| Kazanbiev, NK | 1 |
| Cukier, A | 2 |
| Vargas, FS | 2 |
| Teixeira, LR | 2 |
| Grupi, CJ | 1 |
| Terra-Filho, M | 2 |
| Carvalho-Pinto, RM | 1 |
| Light, RW | 4 |
| Sacco, C | 1 |
| Braghiroli, A | 1 |
| Grossi, E | 2 |
| Donner, CF | 3 |
| Kawashiro, T | 1 |
| Matuschka, PR | 1 |
| Vissing, RS | 1 |
| Bachmann, K | 3 |
| Sullivan, TJ | 3 |
| Reese, JH | 1 |
| Jauregui, L | 3 |
| Miller, K | 1 |
| Scott, M | 1 |
| Yeh, KC | 1 |
| Stepanavage, M | 1 |
| King, JD | 1 |
| Schwartz, J | 1 |
| Chuchalin, AG | 2 |
| Tsoĭ, AN | 2 |
| Zaĭtseva, TM | 1 |
| Titova, EV | 1 |
| Medani, SM | 1 |
| Smirnov, MV | 1 |
| Kaziakhmedov, EA | 1 |
| Varriale, P | 1 |
| Ramaprasad, S | 1 |
| Simon, RP | 1 |
| Kropp, R | 1 |
| Göbel, D | 1 |
| Rennard, SI | 2 |
| Friedman, M | 1 |
| Ramsdell, J | 2 |
| Keller, A | 1 |
| Bömches, B | 1 |
| Dekhuijzen, PN | 2 |
| van der Heijden, HF | 1 |
| van Herwaarden, CL | 5 |
| Crimi, E | 1 |
| Orefice, U | 1 |
| De Benedetto, F | 1 |
| Brusasco, V | 1 |
| Bury, T | 1 |
| Corhay, JL | 1 |
| Louis, R | 1 |
| Radermecker, MF | 1 |
| Tsai, J | 1 |
| Chern, TL | 1 |
| Hu, SC | 1 |
| Lee, CH | 1 |
| Wang, RB | 1 |
| Deng, JF | 1 |
| Dash, A | 1 |
| Agrawal, A | 1 |
| Venkat, N | 1 |
| Moxham, J | 2 |
| Ponte, J | 1 |
| Yernault, JC | 1 |
| Noseda, A | 1 |
| Barr, JT | 1 |
| Schumacher, GE | 1 |
| Luks, DB | 1 |
| Karpel, J | 1 |
| Coll, R | 1 |
| Morera, J | 1 |
| Nishimura, K | 5 |
| Koyama, H | 5 |
| Ikeda, A | 4 |
| Sugiura, N | 1 |
| Kawakatsu, K | 2 |
| Izumi, T | 5 |
| Self, T | 2 |
| Abou-Shala, N | 1 |
| van den Brekel, AM | 1 |
| Harrington, L | 1 |
| Eliraz, A | 1 |
| Sternfeld, M | 1 |
| Madar, Z | 1 |
| Li, Z | 1 |
| Chen, G | 1 |
| Newman, D | 1 |
| Tamir, J | 1 |
| Speedy, L | 1 |
| Newman, JP | 1 |
| Ben-Dov, I | 2 |
| Iversen, ET | 1 |
| Eiken, PA | 1 |
| Nielsen, LM | 1 |
| Laursen, LC | 1 |
| Maltbaek, N | 1 |
| Tønnesen, FV | 1 |
| Rasmussen, FV | 1 |
| Echevarria, KH | 1 |
| Meslier, N | 1 |
| Racineux, JL | 1 |
| Holford, N | 2 |
| Hashimoto, Y | 1 |
| Sheiner, LB | 1 |
| Black, P | 1 |
| Couch, R | 1 |
| Kennedy, J | 1 |
| Briant, R | 1 |
| Karpel, JP | 1 |
| Kotch, A | 1 |
| Zinny, M | 1 |
| Pesin, J | 1 |
| Alleyne, W | 1 |
| Gayan-Ramirez, G | 1 |
| Buts, N | 1 |
| Decramer, M | 2 |
| Jacobs, M | 1 |
| Fink, G | 1 |
| Kaye, C | 1 |
| Sulkes, J | 1 |
| Gabbay, U | 1 |
| Spitzer, SA | 1 |
| Salikova, VV | 1 |
| Nonikov, VE | 1 |
| Belousov, IuB | 1 |
| Bardsley, PA | 1 |
| Mulloy, E | 2 |
| McNicholas, WT | 3 |
| Sides, G | 1 |
| Matera, MG | 3 |
| Cazzola, M | 5 |
| Lampa, E | 1 |
| Santangelo, G | 3 |
| Paizis, G | 1 |
| Vinciguerra, A | 1 |
| Rossi, F | 2 |
| Rasmussen, KG | 1 |
| Zorumski, CF | 1 |
| Senju, S | 1 |
| Toyoshima, H | 1 |
| Miyahara, S | 1 |
| Aritomi, T | 1 |
| Watanabe, K | 1 |
| Ishibashi, M | 2 |
| Yoshida, M | 2 |
| Lusuardi, M | 1 |
| Capelli, A | 1 |
| Tandon, MK | 2 |
| Entzian, P | 1 |
| Barth, J | 1 |
| Kirsten, DK | 1 |
| Wegner, RE | 1 |
| Jörres, RA | 1 |
| Schmidt, M | 1 |
| Jubran, A | 1 |
| Gross, N | 1 |
| Simonian, R | 1 |
| Schuttenhelm, K | 1 |
| Sax, M | 1 |
| Kaniecki, DJ | 1 |
| Arnold, RJ | 1 |
| Sonnenberg, FA | 1 |
| Blasco Navalpotro, MA | 1 |
| Zaragoza Crespo, R | 1 |
| Corrales Rodríguez de Tembleque, M | 1 |
| Rábago Sociats, R | 1 |
| Sacristán, JA | 4 |
| Chantal, P | 1 |
| Soto, J | 4 |
| Holzer, R | 2 |
| Burkhart, KK | 1 |
| Vaz Fragoso, CA | 1 |
| Miller, MA | 1 |
| McKay, SE | 1 |
| Howie, CA | 1 |
| Thomson, AH | 1 |
| Carsuzaa, F | 1 |
| Schranz, J | 1 |
| Casner, PR | 1 |
| Reilly, R | 1 |
| Ho, H | 1 |
| Waterhouse, JC | 1 |
| Pritchard, SM | 1 |
| Howard, P | 1 |
| Hamdy, RC | 1 |
| Micklewright, M | 1 |
| Beecham, VF | 1 |
| Moore, SW | 1 |
| Atsmon, J | 1 |
| Priel, IE | 1 |
| Dolev, E | 1 |
| Santos, SR | 1 |
| Donzella, H | 1 |
| Tanigawara, Y | 2 |
| Komada, F | 1 |
| Shimizu, T | 1 |
| Iwakawa, S | 1 |
| Iwai, T | 1 |
| Maekawa, H | 1 |
| Hori, R | 2 |
| Okumura, K | 2 |
| Ramsdell, JW | 2 |
| Henderson, S | 1 |
| Renvall, MJ | 2 |
| Salmon, DP | 1 |
| Ferguson, P | 1 |
| Mahon, J | 1 |
| Laupacis, A | 2 |
| Donner, A | 2 |
| Wood, T | 1 |
| Jaspersen, D | 1 |
| van Schayck, CP | 1 |
| van Weel, C | 1 |
| Molema, J | 1 |
| Messerschmidt, K | 1 |
| Dockens, RC | 1 |
| Rapoport, D | 1 |
| Roberts, D | 1 |
| Greene, DS | 1 |
| Barbhaiya, RH | 1 |
| Lubischer, AV | 1 |
| Lucas, LM | 1 |
| Porta, M | 1 |
| Bolumar, F | 1 |
| Hernandez, I | 1 |
| Vioque, J | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Smell in COVID-19 and Efficacy of Nasal Theophylline 3[NCT05947643] | Phase 2 | 240 participants (Anticipated) | Interventional | 2022-11-22 | Recruiting | ||
| Effect of Ice and Airflow Stimulation Versus Controlled Breathing Exercises to Reduce Dyspnea in Patients With Obstructive Lung Disease[NCT03887364] | 126 participants (Actual) | Interventional | 2018-02-02 | Completed | |||
| Validation of the Risk Stratification Score in Idiopathic Pulmonary Fibrosis[NCT02632123] | 260 participants (Anticipated) | Observational | 2015-12-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
98 reviews available for theophylline and Obstructive Lung Diseases
| Article | Year |
|---|---|
Acebrophylline: an airway mucoregulator and anti-inflammatory agent.
Topics: Adult; Ambroxol; Child; Humans; Lung Diseases, Obstructive; Theophylline | 2007 |
Cardiovascular function in cor pulmonale.
Topics: Adrenergic beta-Agonists; Cardiac Output; Cardiovascular System; Digitalis Glycosides; Diuretics; Ec | 1983 |
Theophylline reassessed.
Topics: Acidosis; Aging; Allopurinol; Animals; Anti-Bacterial Agents; Breast Feeding; Bronchodilator Agents; | 1984 |
[Effect of theophylline on the contractility of the diaphragm].
Topics: Diaphragm; Humans; Lung Diseases, Obstructive; Muscle Contraction; Pulmonary Emphysema; Theophylline | 1983 |
Therapy of chronic obstructive airways disease.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antitussive Agents; Asthma; Expectorants; Humans; Lu | 1984 |
Theophylline in stable chronic airflow obstruction. A reappraisal.
Topics: Administration, Oral; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Physical E | 1984 |
Pharmacologic management of reversible obstructive airways disease.
Topics: Adrenal Cortex Hormones; Asthma; Bronchodilator Agents; Cromolyn Sodium; Humans; Lung Diseases, Obst | 1981 |
Noninvasive radiographic assessment of cardiovascular function in acute and chronic respiratory failure.
Topics: Acute Disease; Aminophylline; Blood Pressure; Cardiovascular System; Chronic Disease; Cystic Fibrosi | 1981 |
[Treatment of respiratory insufficiency in chronic nonspecific lung diseases].
Topics: Adrenergic beta-Agonists; Anti-Bacterial Agents; Bronchodilator Agents; Expectorants; Glucocorticoid | 1995 |
[Drug therapy of chronic phase in chronic obstructive pulmonary disease].
Topics: Adrenergic beta-Agonists; Cholinergic Antagonists; Expectorants; Humans; Lung Diseases, Obstructive; | 1995 |
Combination bronchodilator therapy in COPD.
Topics: Adrenergic beta-Agonists; Bronchodilator Agents; Cholinergic Antagonists; Drug Therapy, Combination; | 1995 |
Use of theophylline in the treatment of COPD.
Topics: Aged; Costs and Cost Analysis; Dose-Response Relationship, Drug; Exercise Tolerance; Humans; Lung Di | 1995 |
[Bronchodilator treatment of patients with COPD (1994)].
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Algorithms; Bronchodilator Agents; Cholinergic An | 1994 |
[Management of patients with chronic obstructive pulmonary disease].
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Aged; Anti-Bacterial Agents; Antidepressive Agent | 1994 |
[Bronchodilator treatment of chronic obstructive bronchopneumopathies].
Topics: Adrenergic beta-Agonists; Clinical Trials as Topic; Humans; Lung Diseases, Obstructive; Parasympatho | 1993 |
Maintenance therapy for obstructive lung disease. How to achieve the best response with the fewest agents.
Topics: Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adult; Bronchodilator Age | 1994 |
Review of the clinical efficacy of theophylline in the treatment of chronic obstructive pulmonary disease.
Topics: Animals; Cardiovascular System; Dyspnea; Humans; Lung Diseases, Obstructive; Mucous Membrane; Muscle | 1993 |
Influenza vaccine may enhance theophylline toxicity. A case report and review of the literature.
Topics: Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Humans; Influe | 1995 |
[Reflux associated respiratory tract diseases].
Topics: Bronchiectasis; Bronchitis; Bronchodilator Agents; Chronic Disease; Esophagogastric Junction; Gastro | 1996 |
[Drug treatment of chronic obstructive pulmonary disease].
Topics: Adrenergic beta-Agonists; Bronchodilator Agents; Clinical Protocols; Drug Therapy, Combination; Huma | 1996 |
The use of theophylline in chronic obstructive pulmonary disease.
Topics: Animals; Humans; Lung Diseases, Obstructive; Theophylline | 1996 |
[Theophylline and selective phosphodiesterase inhibitor in therapy of obstructive respiratory tract diseases].
Topics: Bronchodilator Agents; Drug Therapy, Combination; Humans; Lung Diseases, Obstructive; Phosphodiester | 1997 |
[Role of theophylline in treatment of chronic obstructive pulmonary disease].
Topics: Bronchi; Humans; Lung Diseases, Obstructive; Respiratory Function Tests; Theophylline | 1997 |
[Evaluation of hyperkinetic cardiac arrhythmia in chronic obstructive bronchopneumopathy].
Topics: Adrenergic beta-Agonists; Arrhythmias, Cardiac; Bronchodilator Agents; Bronchopneumonia; Digitalis G | 1997 |
Theophylline: recent advances in the understanding of its mode of action and uses in clinical practice.
Topics: Apnea; Apoptosis; Asthma; Calcium Channels; Capillary Leak Syndrome; Catecholamines; Erythropoietin; | 1998 |
Standards of laboratory practice: theophylline and caffeine monitoring. National Academy of Clinical Biochemistry.
Topics: Apnea; Bronchodilator Agents; Caffeine; Drug Monitoring; Humans; Infant, Newborn; Lung Diseases, Obs | 1998 |
[Bronchodilator treatment of COPD].
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Albuterol; Bronchodilator Agents; Clinical Trials | 1998 |
[Theophylline in treatment of bronchial obstructive diseases].
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents; Asthma; Bronchial Diseases; Bronchial Spasm; Bronc | 1998 |
Therapeutic activities of theophylline in chronic obstructive pulmonary disease.
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents; Bronchodilator Agents; Cytokines; Dose-Response Re | 1998 |
[Etiology, diagnosis and therapy of COPD].
Topics: Administration, Inhalation; Anti-Inflammatory Agents; Bronchodilator Agents; Humans; Lung Diseases, | 1999 |
Adenosine receptor ligands: potential as therapeutic agents in asthma and COPD.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Humans; Ligands; Lung Diseases, Obstr | 1999 |
Long acting beta(2) agonists and theophylline in stable chronic obstructive pulmonary disease.
Topics: Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Bronchodilator Agents; D | 1999 |
Stable chronic obstructive pulmonary disease.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Bronchodilator Agents; Cholinergic Antagonists; E | 1999 |
[Recent progress on the therapy for chronic obstructive pulmonary disease (COPD)--usefulness and practice of the step-by-step pharmacologic therapy].
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Androstadienes; Bronchodilator Agents; Choline | 1999 |
[Acute exacerbations of chronic obstructive pulmonary disease: special reference to pathophysiology and management].
Topics: Adrenergic beta-Agonists; Anti-Inflammatory Agents; Cholinergic Antagonists; Disease Progression; Hu | 1999 |
Impact of sleep in COPD.
Topics: Adrenergic beta-Agonists; Almitrine; Carbon Dioxide; Cholinergic Antagonists; Humans; Lung Diseases, | 2000 |
How should health-related quality of life be assessed in patients with COPD?
Topics: Adrenergic beta-Agonists; Cholinergic Antagonists; Clinical Trials as Topic; Humans; Lung Diseases, | 2000 |
Bronchodilator therapy in chronic obstructive pulmonary disease.
Topics: Adrenergic beta-Agonists; Albuterol; Bronchodilator Agents; Cholinergic Antagonists; Drug Therapy, C | 2000 |
Phosphodiesterase 4 inhibitors, structurally unrelated to rolipram, as promising agents for the treatment of asthma and other pathologies.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Arthritis, Rheumatoid; Asthma; Cyclic Nucleotide Phosphodiester | 2000 |
Novel therapy for COPD.
Topics: Adrenergic beta-Agonists; Animals; Anti-Bacterial Agents; Antioxidants; Bronchodilator Agents; Chemo | 2000 |
Respiratory muscle function and drive in chronic obstructive pulmonary disease.
Topics: Biomechanical Phenomena; Humans; Lung Diseases, Obstructive; Muscle Weakness; Respiration; Respirato | 2000 |
The chronic obstructive pulmonary disease exacerbation.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Bacterial Infections; Bronchodilator Agents; Dietary | 2000 |
[Theophylline--contemporary views on cellular mechanism of action].
Topics: Adenosine; Animals; Calcium; Catecholamines; Enzyme Activation; Humans; Isoenzymes; Lung Diseases, O | 2000 |
Anticholinergic bronchodilators in combination.
Topics: Bronchodilator Agents; Cholinergic Antagonists; Drug Combinations; Humans; Lung Diseases, Obstructiv | 2000 |
Doxofylline: a new generation xanthine bronchodilator devoid of major cardiovascular adverse effects.
Topics: Animals; Arrhythmias, Cardiac; Asthma; Bronchodilator Agents; Cardiovascular Diseases; Drug Evaluati | 2001 |
[Theophylline--mechanism of action in the respiratory tract].
Topics: Anti-Inflammatory Agents; Asthma; Bronchi; Diaphragm; Humans; Lung; Lung Diseases, Obstructive; Musc | 2000 |
Inhaled salmeterol: a review of its efficacy in chronic obstructive pulmonary disease.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Bronchodilator Agents; Cardiovascul | 2001 |
[Drug therapy of COPD].
Topics: Adrenal Cortex Hormones; Cholinergic Antagonists; Humans; Lung Diseases, Obstructive; Sympathomimeti | 2001 |
[Drug therapy of obstructive lung diseases].
Topics: Adrenergic beta-Agonists; Cholinergic Antagonists; Drug Therapy, Combination; Glucocorticoids; Human | 2001 |
Treating dyspnea in a patient with advanced chronic obstructive pulmonary disease.
Topics: Administration, Inhalation; Aged; Anti-Anxiety Agents; Breathing Exercises; Bronchodilator Agents; D | 2001 |
[Conventional therapy exemplified by COPD].
Topics: Adrenal Cortex Hormones; Bronchodilator Agents; Combined Modality Therapy; Expectorants; Humans; Lun | 1992 |
Acute exacerbations of COPD. How to evaluate severity and treat the underlying cause.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Expectorants; Humans; Lung Diseases, Obstructive; | 1992 |
Pharmacologic treatment of COPD. Optimum therapy for ambulatory patients.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Ambulatory Care; Drug Therapy, Combination; Expec | 1992 |
[Interactions of theophylline and H2 receptor antagonists. Interaction modes--clinical relevance].
Topics: Drug Interactions; Drug Therapy, Combination; Histamine H2 Antagonists; Humans; Lung Diseases, Obstr | 1992 |
COPD: primary care management with drug and oxygen therapies.
Topics: Aged; Anti-Bacterial Agents; Bronchodilator Agents; Clinical Protocols; Geriatrics; Humans; Lung Dis | 1992 |
Right ventricular function at rest and during exercise in chronic obstructive pulmonary disease.
Topics: Digitalis; Exercise; Humans; Lung Diseases, Obstructive; Oxygen Inhalation Therapy; Plants, Medicina | 1992 |
[Advances in the drug therapy of pulmonary hypertension in patients with chronic obstructive pulmonary disease].
Topics: Animals; Atrial Natriuretic Factor; Calcium Channel Blockers; Humans; Hypertension, Pulmonary; Lung | 1991 |
Dyspnea in the patient with chronic obstructive pulmonary disease. Etiology and management.
Topics: Anti-Anxiety Agents; Breathing Exercises; Bronchodilator Agents; Dyspnea; Humans; Lung Diseases, Obs | 1990 |
Cor pulmonale in chronic obstructive pulmonary disease. Circulatory pathophysiology and management.
Topics: Adrenergic beta-Agonists; Almitrine; Bloodletting; Digitalis Glycosides; Humans; Lung Diseases, Obst | 1990 |
Use of beta 2-adrenergic drugs in obstructive respiratory tract diseases of childhood.
Topics: Adrenergic beta-Agonists; Child; Child, Preschool; Drug Therapy, Combination; Humans; Infant; Lung D | 1990 |
Theophylline in asthma and COPD: changing perspectives and controversies.
Topics: Asthma; Humans; Lung Diseases, Obstructive; Mucociliary Clearance; Theophylline | 1991 |
Management of chronic airway obstruction: theophylline--is it still necessary?
Topics: Airway Resistance; Asthma; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Respiratory | 1990 |
Management of asthma and chronic airflow limitation: are methylxanthines obsolete?
Topics: Adrenal Cortex Hormones; Airway Resistance; Aminophylline; Asthma; Bronchodilator Agents; Drug Thera | 1990 |
Theophylline in the management of airflow obstruction. 1. Much evidence suggests that theophylline is valuable.
Topics: Asthma; Humans; Lung Diseases, Obstructive; Theophylline | 1990 |
Theophylline in the management of airflow obstruction. 2. Difficult drugs to use, few clinical indications.
Topics: Acute Disease; Adult; Asthma; Child, Preschool; Chronic Disease; Humans; Lung Diseases, Obstructive; | 1990 |
Management of asthma and chronic airflow limitation. Are methylxanthines obsolete?
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Aminophylline; Asthma; Bronchodilator Agents; H | 1990 |
Pharmacologic therapy of obstructive airway disease.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Expectorants; Humans; Lung Diseases, Obstructive; Ox | 1990 |
Pharmacologic strategies for treating respiratory failure.
Topics: Animals; Digoxin; Dopamine; Humans; Lung Diseases, Obstructive; Respiratory Insufficiency; Respirato | 1990 |
Clinical efficacy of ciprofloxacin in lower respiratory tract infections.
Topics: Ciprofloxacin; Clinical Trials as Topic; Cystic Fibrosis; Drug Interactions; Humans; Lung Diseases, | 1989 |
[Therapy of obstructive respiratory tract diseases. II: Xanthines, calcium antagonists and VIP].
Topics: Calcium Channel Blockers; Humans; Lung Diseases, Obstructive; Theophylline; Vasoactive Intestinal Pe | 1989 |
[A strategy of drug treatment of obstructive respiratory tract diseases].
Topics: Bronchodilator Agents; Glucocorticoids; Humans; Lung Diseases, Obstructive; Theophylline | 1989 |
[Theophylline in the treatment of asthma: indications, use and side effects].
Topics: Asthma; Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Lung Diseases, Obstru | 1989 |
Tulobuterol in the management of obstructive airways disease in adults.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Aged; Asthma; Bronchodilator Agents; Femal | 1985 |
Theophylline in chronic obstructive pulmonary disease.
Topics: Adrenergic beta-Agonists; Cardiovascular System; Drug Therapy, Combination; Humans; Lung Diseases, O | 1986 |
Pharmacologic management of obstructive lung disease. Current perspectives.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Cromolyn Sodium; Humans; Lung Diseases, Obstructi | 1986 |
Pharmacotherapy of chronic obstructive pulmonary disease.
Topics: Adrenergic beta-Antagonists; Adrenergic Fibers; Autonomic Nervous System; Bronchodilator Agents; Glu | 1986 |
Theophylline as a bronchodilator in COPD and its combination with inhaled beta-adrenergic drugs.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Asthma; Bronchi; Bronchitis; Clinical Trials as Topic; | 1987 |
COPD in the ambulatory elderly: management update.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aged; Anti-Bacterial Agents; Humans; Lung Dise | 1988 |
[Inflammatory mediators in the pathogenesis of obstructive bronchial diseases: consequences for therapy].
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Humans; Leukotrienes; Lung Diseases, Obstructive; | 1988 |
New concepts in bronchodilator therapy.
Topics: Adrenal Cortex Hormones; Asthma; Atropine; Bronchodilator Agents; Calcium Channel Blockers; Fenotero | 1986 |
Biochemical and cellular basis for circadian rhythms in obstructive lung disease and implications for theophylline therapy.
Topics: Asthma; Circadian Rhythm; Humans; Lung Diseases, Obstructive; Theophylline | 1988 |
The use of theophylline in 'irreversible' chronic obstructive pulmonary disease. An update.
Topics: Administration, Oral; Drug Interactions; Humans; Infusions, Intravenous; Lung Diseases, Obstructive; | 1988 |
[The value of theophylline therapy in the treatment of obstructive respiratory tract diseases].
Topics: Dose-Response Relationship, Drug; Humans; Lung Diseases, Obstructive; Theophylline | 1988 |
[Theophylline in chronic obstructive lung disease].
Topics: Humans; Lung Diseases, Obstructive; Theophylline | 1988 |
The role of theophylline in the treatment of dyspnea in COPD.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Dyspnea; Exercise Test; Forced Expirator | 1987 |
Effect of theophylline on diaphragmatic muscle function.
Topics: Aminophylline; Animals; Diaphragm; Electromyography; Humans; Lung Diseases, Obstructive; Muscle Cont | 1987 |
Favorable cardiovascular effects of theophylline in COPD.
Topics: Administration, Oral; Aminophylline; Blood Pressure; Cardiovascular System; Delayed-Action Preparati | 1987 |
The effects of theophylline on airway inflammation.
Topics: Adult; Animals; Anti-Inflammatory Agents; Asthma; Bronchi; Bronchial Provocation Tests; Bronchitis; | 1987 |
Theophylline and mucociliary clearance.
Topics: Aminophylline; Animals; Asthma; Bronchitis; Cilia; Clinical Trials as Topic; Dogs; Humans; Lung Dise | 1987 |
[Theophylline in the therapy of non reversible airway obstruction].
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Humans; Lung Diseases, Obstructive; Middle Aged; | 1987 |
Theophylline steady-state pharmacokinetics: recent concepts and their application in chronotherapy of reactive airway diseases.
Topics: Circadian Rhythm; Delayed-Action Preparations; Drug Administration Schedule; Humans; Kinetics; Lung | 1987 |
Chronic obstructive pulmonary disease.
Topics: Adrenal Cortex Hormones; Aged; Bloodletting; Breathing Exercises; Bronchitis; Bronchodilator Agents; | 1986 |
Effect of disease states on theophylline elimination.
Topics: Animals; Disease; Heart Failure; Humans; Kinetics; Liver; Lung Diseases, Obstructive; Metabolic Clea | 1986 |
Effect of theophylline on diaphragmatic and other skeletal muscle function.
Topics: Animals; Diaphragm; Humans; In Vitro Techniques; Lung Diseases, Obstructive; Muscle Contraction; Mus | 1986 |
Theophylline improves global cardiac function and reduces dyspnea in chronic obstructive lung disease.
Topics: Dyspnea; Heart; Hemodynamics; Humans; Lung Diseases, Obstructive; Myocardial Contraction; Theophylli | 1986 |
Respiratory muscle function.
Topics: Diaphragm; Humans; Intercostal Muscles; Lung Diseases, Obstructive; Nutritional Physiological Phenom | 1986 |
Effects of theophylline on cardiovascular performance in chronic obstructive pulmonary disease.
Topics: Administration, Oral; Aminophylline; Blood Pressure; Delayed-Action Preparations; Heart Rate; Hemody | 1985 |
Update on the pharmacodynamics and pharmacokinetics of theophylline.
Topics: Asthma; Biotransformation; Delayed-Action Preparations; Drug Interactions; Food; Humans; Intestinal | 1985 |
164 trials available for theophylline and Obstructive Lung Diseases
| Article | Year |
|---|---|
Efficacy and safety of oxitropium bromide, theophylline and their combination in COPD patients: a double-blind, randomized, multicentre study (BREATH Trial).
Topics: Aged; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lung Diseases, Obstructive; Ma | 2002 |
Theophylline does not potentiate the effects of a low dose of dexamethasone in horses with recurrent airway obstruction.
Topics: Administration, Oral; Animals; Bronchodilator Agents; Cross-Over Studies; Dexamethasone; Dose-Respon | 2006 |
Effects of enprofylline, a xanthine lacking adenosine receptor antagonism, in patients with chronic obstructive lung disease.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Forced Expiratory Volume; Hemodynamics; Humans; Lung | 1982 |
Slow release theophylline in patients with airways obstruction with particular reference to the effects of food upon serum levels.
Topics: Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Fasting; Female; Food; Humans; L | 1983 |
[The effect of theophylline in slow-release or regular preparations in chronic obstructive lung disease. A double-blind study comparing Nuelin Depot, Nuelin and placebo].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lung Disease | 1983 |
Effect of inhaled atropine or metaproterenol in patients with chronic airway obstruction and therapeutic serum theophylline levels.
Topics: Aerosols; Atropine; Clinical Trials as Topic; Double-Blind Method; Forced Expiratory Flow Rates; For | 1984 |
Comparison of the bronchodilating effect of two doses of a sustained release theophylline.
Topics: Adult; Aged; Biological Availability; Carbon Dioxide; Delayed-Action Preparations; Dose-Response Rel | 1984 |
Protective effect of various drugs in preventing an acetylcholine-induced bronchoconstriction.
Topics: Acetylcholine; Adult; Aged; Airway Resistance; Albuterol; Allergens; Clinical Trials as Topic; Ethyl | 1980 |
The effect of maintenance theophylline therapy on lung work in severe chronic obstructive pulmonary disease while standing and walking.
Topics: Forced Expiratory Volume; Humans; Locomotion; Lung; Lung Compliance; Lung Diseases, Obstructive; Mal | 1984 |
Physiologic effects of oral bronchodilators during rest and exercise in chronic obstructive pulmonary disease.
Topics: Administration, Oral; Aged; Bronchodilator Agents; Exercise Test; Humans; Lung; Lung Diseases, Obstr | 1983 |
The influence of ketotifen and aminophylline on the central and peripheral airways.
Topics: Adult; Aged; Aminophylline; Asthma; Double-Blind Method; Female; Humans; Ketotifen; Lung Diseases, O | 1983 |
Effects of theophylline on diaphragmatic strength and fatigue in patients with chronic obstructive pulmonary disease.
Topics: Diaphragm; Humans; Lung Diseases, Obstructive; Middle Aged; Muscle Contraction; Respiration; Theophy | 1984 |
[Treatment of chronic obstructive respiratory disease with a new purified theophylline preparation in delayed-action form].
Topics: Aged; Airway Resistance; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Huma | 1984 |
The efficacy of isoproterenol inhalation for predicting the response to orally administered theophylline in chronic obstructive pulmonary disease.
Topics: Administration, Intranasal; Administration, Oral; Aged; Clinical Trials as Topic; Double-Blind Metho | 1982 |
Comparative studies of atropine methonitrate and its combination with reproterol in chronic airway obstruction.
Topics: Aerosols; Atropine Derivatives; Bronchitis; Bronchodilator Agents; Clinical Trials as Topic; Double- | 1982 |
[Therapy of obstructive respiratory tract diseases with pure theophylline retard].
Topics: Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obstru | 1982 |
[Therapy of obstructive respiratory tract diseases. Study of afonilum retard in 3,512 patients].
Topics: Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Lung Diseases, O | 1982 |
[Theophylline therapy in obstructive respiratory diseases. 2. Theophyllin-retard preparations for the long-term treatment of non-smokers with or without cardiac insufficiency (author's transl)].
Topics: Adolescent; Adult; Aged; Delayed-Action Preparations; Female; Heart Failure; Humans; Long-Term Care; | 1981 |
[Optimizing therapy with theophylline preparations in obstructive ventilation disorders. 3. Prediction of theophylline clearance with a simple pharmacokinetic method and comparison of bioavailability of various theophylline retard preparations].
Topics: Adult; Aged; Biological Availability; Delayed-Action Preparations; Female; Humans; Kinetics; Lung Di | 1983 |
Cardiopulmonary effects of terbutaline and a bronchodilator combination in chronic obstructive pulmonary disease.
Topics: Adult; Aged; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Drug Combinations | 1980 |
Treatment of chronic obstructive pulmonary disease with orally administered theophylline. A double-blind, controlled study.
Topics: Administration, Oral; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Humans; Lung; | 1980 |
Sustained release oral aminophylline in patients with airflow obstruction.
Topics: Adult; Aged; Aminophylline; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Meth | 1981 |
[Postoperative respiratory therapy: bronchospasmolytic activity and side-effects of some recently introduced beta-sympatheticomimetic agents (author's transl)].
Topics: Adult; Aged; Asthma; Bronchial Spasm; Bronchitis; Clinical Trials as Topic; Drug Combinations; Ethan | 1981 |
The combined effect of theophylline and terbutaline in patients with chronic obstructive airway diseases.
Topics: Administration, Oral; Adult; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combinatio | 1982 |
[Obstructive airway diseases. Basic therapy with pure theophylline in retard form].
Topics: Adult; Aged; Airway Resistance; Asthma; Bronchitis; Clinical Trials as Topic; Delayed-Action Prepara | 1982 |
Maintenance of bronchodilation in chronic reversible airways obstruction. Comparison between choline theophyllinate and salbutamol.
Topics: Adult; Albuterol; Choline; Clinical Trials as Topic; Female; Forced Expiratory Flow Rates; Humans; L | 1982 |
Effects of theophylline on breathlessness and exercise tolerance in patients with chronic airflow obstruction.
Topics: Adult; Aged; Airway Obstruction; Drug Evaluation; Forced Expiratory Volume; Hemodynamics; Humans; Lu | 1982 |
[Pharmacokinetic and clinical effectiveness of rectally administered theophylline].
Topics: Adult; Aged; Aminophylline; Blood Pressure; Double-Blind Method; Drug Combinations; Dyphylline; Huma | 1982 |
Isoproterenol challenge during placebo and oral theophylline therapy in chronic obstructive pulmonary disease.
Topics: Bronchial Provocation Tests; Drug Antagonism; Humans; Isoproterenol; Lung Diseases, Obstructive; Mal | 1981 |
Arrhythmogenic effects of combined orally administered theophylline and albuterol in patients with chronic obstructive pulmonary disease.
Topics: Administration, Oral; Aged; Albuterol; Arrhythmias, Cardiac; Bronchodilator Agents; Drug Therapy, Co | 1994 |
The effects of doxofylline versus theophylline on sleep architecture in COPD patients.
Topics: Adult; Aged; Antitussive Agents; Arousal; Cross-Over Studies; Forced Expiratory Volume; Humans; Lung | 1995 |
Clinafloxacin-theophylline drug interaction.
Topics: Aged; Anti-Infective Agents; Cross Infection; Delayed-Action Preparations; Drug Interactions; Drug M | 1995 |
Controlled study of the putative interaction between famotidine and theophylline in patients with chronic obstructive pulmonary disease.
Topics: Adult; Aged; Cimetidine; Cross-Over Studies; Drug Interactions; Famotidine; Female; Humans; Infusion | 1995 |
Nedocromil sodium versus theophylline in the treatment of reversible obstructive airway disease.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Drug Evaluation; Drug Tolerance; Female; Humans; Lung | 1995 |
Effect of oral theophylline on resting energy expenditure in normal volunteers.
Topics: Adult; Albuterol; Carbon Dioxide; Double-Blind Method; Drug Interactions; Energy Metabolism; Female; | 1994 |
The additive effect of theophylline on a high-dose combination of inhaled salbutamol and ipratropium bromide in stable COPD.
Topics: Administration, Inhalation; Aged; Albuterol; Bronchi; Cross-Over Studies; Double-Blind Method; Drug | 1995 |
Glycaemic and insulinaemic index of meals in stable obstructive pulmonary disease subjects.
Topics: Blood Glucose; Case-Control Studies; Dietary Carbohydrates; Dietary Fiber; Drug Therapy, Combination | 1994 |
[Evaluation of theophylline population pharmacokinetics in adult hospitalized patients using NONMEM analysis].
Topics: Adolescent; Adult; Age Factors; Aged; Asthma; Drug Therapy, Combination; Female; Humans; Lung Diseas | 1994 |
Physiological and neuropsychological effects of theophylline in chronic obstructive pulmonary disease.
Topics: Aged; Bronchial Provocation Tests; Child; Cognition; Double-Blind Method; Exercise Test; Female; Hum | 1994 |
[Theophylline treatment of irreversible, chronic obstructive pulmonary disease].
Topics: Adult; Aged; Cross-Sectional Studies; Double-Blind Method; Female; Humans; Lung Diseases, Obstructiv | 1994 |
Time and theophylline concentration help explain the recovery of peak flow following acute airways obstruction. Population analysis of a randomised concentration controlled trial.
Topics: Adult; Double-Blind Method; Female; Humans; Lung Diseases, Obstructive; Male; Models, Statistical; P | 1993 |
Theophylline target concentration in severe airways obstruction - 10 or 20 mg/L? A randomised concentration-controlled trial.
Topics: Adult; Double-Blind Method; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Length of Sta | 1993 |
A comparison of inhaled ipratropium, oral theophylline plus inhaled beta-agonist, and the combination of all three in patients with COPD.
Topics: Administration, Inhalation; Administration, Oral; Adult; Aged; Albuterol; Double-Blind Method; Drug | 1994 |
Effect of theophylline on exercise performance in patients with severe chronic obstructive pulmonary disease.
Topics: Aged; Carbon Dioxide; Double-Blind Method; Exercise; Exercise Test; Female; Humans; Lung; Lung Disea | 1994 |
[The comparative efficacy of the prolonged-action theophylline preparations Theopek and Euphylong in elderly patients with chronic obstructive lung diseases].
Topics: Aged; Asthma; Bronchitis; Chronic Disease; Delayed-Action Preparations; Female; Humans; Lung Disease | 1993 |
Theophylline improves gas exchange during rest, exercise, and sleep in severe chronic obstructive pulmonary disease.
Topics: Aged; Analysis of Variance; Double-Blind Method; Exercise; Female; Humans; Lung Diseases, Obstructiv | 1993 |
Clinical pharmacokinetics of theophylline during co-treatment with ticarcillin plus clavulanic acid in patients suffering from acute exacerbation of chronic bronchitis.
Topics: beta-Lactamase Inhibitors; Bronchitis; Clavulanic Acids; Drug Therapy, Combination; Humans; Lung Dis | 1993 |
Is oral theophylline effective in combination with both inhaled anticholinergic agent and inhaled beta 2-agonist in the treatment of stable COPD?
Topics: Administration, Oral; Aerosols; Aged; Albuterol; Delayed-Action Preparations; Double-Blind Method; D | 1993 |
Double-blind crossover study of nedocromil sodium in partially reversible chronic obstructive airways disease.
Topics: Adult; Aged; Aged, 80 and over; Albuterol; Anti-Inflammatory Agents, Non-Steroidal; Beclomethasone; | 1993 |
Effects of theophylline withdrawal in severe chronic obstructive pulmonary disease.
Topics: Aged; Double-Blind Method; Dyspnea; Exercise Tolerance; Female; Humans; Lung Diseases, Obstructive; | 1993 |
[Tolerance and effect of short-term theophylline infusions].
Topics: Adolescent; Adult; Aged; Aminophylline; Drug Administration Schedule; Female; Humans; Infusions, Int | 1993 |
[Comparison of two long-acting theophylline preparations in daily evening administration].
Topics: Adult; Aged; Airway Resistance; Asthma; Delayed-Action Preparations; Dose-Response Relationship, Dru | 1993 |
Value of theophylline treatment in patients handicapped by chronic obstructive lung disease.
Topics: Adrenal Cortex Hormones; Adult; Aged; Bronchodilator Agents; Delayed-Action Preparations; Double-Bli | 1993 |
A randomized controlled trial of computerized pharmacokinetic theophylline dosing versus empiric physician dosing.
Topics: Aged; Asthma; Carbon Dioxide; Decision Making; Drug Therapy, Computer-Assisted; Female; Humans; Hydr | 1993 |
Hyperinflation, trapped gas and theophylline in chronic obstructive pulmonary disease.
Topics: Aged; Double-Blind Method; Female; Forced Expiratory Volume; Functional Residual Capacity; Humans; L | 1993 |
Population pharmacokinetics of theophylline. III. Premarketing study for a once-daily administered preparation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Analysis of Variance; Asthma; Bronchodilator Agen | 1995 |
Effects of theophylline and ipratropium on cognition in elderly patients with chronic obstructive pulmonary disease.
Topics: Aged; Bronchodilator Agents; Cognition; Double-Blind Method; Female; Humans; Ipratropium; Lung Disea | 1996 |
Randomised study of n of 1 trials versus standard practice.
Topics: Aged; Ambulatory Care; Bias; Bronchodilator Agents; Exercise; Female; Follow-Up Studies; Humans; Lun | 1996 |
Lack of an effect of nefazodone on the pharmacokinetics and pharmacodynamics of theophylline during concurrent administration in patients with chronic obstructive pulmonary disease.
Topics: Antidepressive Agents; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Drug Therapy, | 1995 |
Sleep quality and nocturnal respiratory function with once-daily theophylline (Uniphyl) and inhaled salbutamol in patients with COPD.
Topics: Adrenergic beta-Agonists; Albuterol; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; | 1996 |
The effects of theophylline on metabolic rate in chronic obstructive lung disease patients.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Body Composition; Body Temperature Regulation; Bronch | 1996 |
Effects of repeated administration of zolpidem on sleep, diurnal and nocturnal respiratory function, vigilance, and physical performance in patients with COPD.
Topics: Administration, Oral; Aged; Ambulatory Care; Arousal; Bronchodilator Agents; Carbon Dioxide; Circadi | 1996 |
Thermogenic effect of bronchodilators in patients with chronic obstructive pulmonary disease.
Topics: Aged; Albuterol; Bronchodilator Agents; Calorimetry, Indirect; Double-Blind Method; Energy Metabolis | 1997 |
Oral doxophylline in patients with chronic obstructive pulmonary disease.
Topics: Administration, Oral; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Antitussive Agents; Blood Ga | 1997 |
Effects of theophylline on respiratory drive in patients with chronic obstructive pulmonary disease.
Topics: Aged; Analysis of Variance; Bronchodilator Agents; Humans; Lung Diseases, Obstructive; Male; Middle | 1997 |
Effects of theophylline and ipratropium bromide on exercise performance in patients with stable chronic obstructive pulmonary disease.
Topics: Aged; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Drug Combinations; Exercise; E | 1998 |
Theophylline for irreversible chronic airflow limitation: a randomized study comparing n of 1 trials to standard practice.
Topics: Aged; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Exercise Test; Female; Forced | 1999 |
[Effects of theophylline on lung function and sleep in patients with severe chronic obstructive pulmonary disease].
Topics: Aged; Bronchodilator Agents; Circadian Rhythm; Cross-Over Studies; Delayed-Action Preparations; Doub | 1997 |
Salmeterol versus slow-release theophylline in patients with reversible obstructive pulmonary disease.
Topics: Adrenergic beta-Agonists; Albuterol; Bronchodilator Agents; Delayed-Action Preparations; Humans; Lun | 1999 |
Verapamil causes decreased diaphragm endurance but no decrease of nocturnal O(2) saturation in patients with chronic obstructive pulmonary disease.
Topics: Aged; Blood Gas Analysis; Calcium Channel Blockers; Circadian Rhythm; Cross-Over Studies; Diaphragm; | 2000 |
Additive effects of salmeterol and fluticasone or theophylline in COPD.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aged; Albuterol; Androstadienes; Bronchodilato | 2000 |
Salmeterol plus theophylline combination therapy in the treatment of COPD.
Topics: Adrenergic beta-Agonists; Aged; Aged, 80 and over; Albuterol; Bronchodilator Agents; Double-Blind Me | 2001 |
[Comparing the bronchodilating effects of ipratropium bromide and theophylline].
Topics: Adult; Aged; Bronchi; Bronchodilator Agents; Double-Blind Method; Female; Forced Expiratory Volume; | 1998 |
[(Whole body plethysmographic studies on the bronchospasmolytic effect of injectabls drugs. Comparison of aminophylline, diprophylline and hexoprenaline)].
Topics: Adult; Aged; Airway Resistance; Aminophylline; Bronchi; Clinical Trials as Topic; Drug Therapy, Comb | 1976 |
The cardiorespiratory effects of oral terbutaline and an ephedrine-theophylline-phenobarbital combination: comparison in patients with chronic obstructive ventilatory disorders.
Topics: Administration, Oral; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Ephedr | 1978 |
Synergism of metaproterenol and theophylline.
Topics: Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Humans; Lu | 1978 |
The usefulness of theophylline in nonasthmatic airway obstruction.
Topics: Adult; Aged; Airway Obstruction; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Humans; | 1979 |
[Lung function studies with the bronchodilator terbutaline].
Topics: Adult; Aged; Airway Resistance; Asthma; Atropine; Clenbuterol; Drug Combinations; Ethylenediamines; | 1979 |
Response to oral corticosteroid in patients with chronic obstructive pulmonary disease.
Topics: Aged; Albuterol; Eosinophils; Female; Forced Expiratory Volume; Humans; Immunoglobulin E; Ipratropiu | 1992 |
Nocturnal oxygen saturation and sleep quality in patients with advanced chronic obstructive pulmonary disease during treatment with moderate dose CR-theophylline.
Topics: Aged; Circadian Rhythm; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedu | 1992 |
Overnight theophylline concentrations and effects on sleep and lung function in chronic obstructive pulmonary disease.
Topics: Administration, Oral; Adult; Analysis of Variance; Circadian Rhythm; Delayed-Action Preparations; Hu | 1992 |
Effect of theophylline in chronic obstructive lung disease.
Topics: Administration, Oral; Adult; Aged; Delayed-Action Preparations; Double-Blind Method; Humans; Lung Di | 1992 |
Effect of therapeutic theophylline levels on the sleep quality and daytime cognitive performance of normal subjects.
Topics: Adult; Cognition; Delayed-Action Preparations; Double-Blind Method; Drug Evaluation; Female; Humans; | 1992 |
Theophylline and salbutamol improve pulmonary function in patients with irreversible chronic obstructive pulmonary disease.
Topics: Administration, Inhalation; Administration, Oral; Aged; Albuterol; Double-Blind Method; Drug Therapy | 1992 |
What use is steady-state theophylline in severe chronic obstructive pulmonary disease? A preliminary report.
Topics: Humans; Lung; Lung Diseases, Obstructive; Lung Volume Measurements; Theophylline | 1991 |
Control of breathing in patients with chronic pulmonary obstructive disease: response to bamiphylline.
Topics: Aged; Bronchodilator Agents; Electromyography; Forced Expiratory Volume; Humans; Lung Diseases, Obst | 1991 |
[Euphylong in standard dosage: comparison with an international retard preparation for twice-daily administration in recommended dosage].
Topics: Adult; Biological Availability; Circadian Rhythm; Delayed-Action Preparations; Double-Blind Method; | 1991 |
[Multicenter study with a large number of patients for the validation of pharmacokinetic and clinical findings from controlled studies with small patient cohorts].
Topics: Adolescent; Adult; Aged; Drug Administration Schedule; Female; Humans; Lung Diseases, Obstructive; M | 1991 |
Acute bronchodilating effects of ipratropium bromide and theophylline in chronic obstructive pulmonary disease.
Topics: Adult; Aerosols; Aged; Bronchi; Double-Blind Method; Drug Therapy, Combination; Forced Expiratory Vo | 1991 |
Effect of theophylline on sleep and sleep-disordered breathing in patients with chronic obstructive pulmonary disease.
Topics: Arousal; Arteries; Carbon Dioxide; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Mal | 1991 |
Conversion of COPD patients from multiple to single dose theophylline. Serum levels and symptom comparison.
Topics: Aged; Delayed-Action Preparations; Drug Administration Schedule; Female; Forced Expiratory Volume; H | 1991 |
Effects of a combined treatment theophylline and tulobuterol on nocturnal chronic asthma.
Topics: Adrenergic beta-Agonists; Adult; Aged; Asthma; Bronchodilator Agents; Double-Blind Method; Drug Admi | 1990 |
Mechanism of bronchodilator effect in chronic airflow limitation.
Topics: Activities of Daily Living; Aged; Albuterol; Drug Therapy, Combination; Dyspnea; Forced Expiratory V | 1991 |
Bronchodilator treatment for partially reversible chronic obstructive airways disease.
Topics: Aged; Aged, 80 and over; Double-Blind Method; Drug Therapy, Combination; Forced Expiratory Volume; H | 1991 |
Effect of theophylline on cortisol plasma concentrations in patients with chronic obstructive pulmonary disease.
Topics: Aged; Delayed-Action Preparations; Double-Blind Method; Humans; Hydrocortisone; Lung Diseases, Obstr | 1990 |
[Serum theophylline concentrations in patients with chronic obstructive lung diseases: a comparison of 2 methods].
Topics: Adult; Aged; Airway Resistance; Fluorescence Polarization; Fluorescent Antibody Technique; Humans; I | 1990 |
The effect of theophylline on respiratory muscle contractility and fatigue.
Topics: Animals; Diaphragm; Dogs; Double-Blind Method; Fatigue; Guinea Pigs; Humans; Lung Diseases, Obstruct | 1990 |
Comparative assessment of enprofylline and theophylline for chronic obstructive airways disease in the elderly.
Topics: Aged; Bronchodilator Agents; Double-Blind Method; Female; Headache; Humans; Lung Diseases, Obstructi | 1990 |
Predictability and intraindividual variability of serum theophylline concentrations in patients with obstructive lung disease: 12-h versus 24-h dosing.
Topics: Adult; Aged; Bayes Theorem; Delayed-Action Preparations; Drug Administration Schedule; Female; Human | 1990 |
[Clinical effectiveness of delayed-action theophylline preparations].
Topics: Adult; Aged; Bronchi; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Humans; | 1990 |
Effect of cimetidine and ranitidine on plasma theophylline in patients with chronic obstructive airways disease treated with theophylline and corticosteroids.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Delayed-Action Preparations; Drug Interactio | 1990 |
Home monitoring of theophylline levels: a novel therapeutic approach.
Topics: Ambulatory Care; Asthma; Female; Humans; Lung Diseases; Lung Diseases, Obstructive; Male; Monitoring | 1990 |
A comparison of enprofylline and theophylline in the maintenance therapy of chronic reversible obstructive airway disease.
Topics: Adolescent; Adult; Aged; Bronchodilator Agents; Delayed-Action Preparations; Dose-Response Relations | 1990 |
Combination of theophylline and salbutamol for arrhythmias in severe COPD.
Topics: Aged; Albuterol; Cardiac Complexes, Premature; Drug Therapy, Combination; Female; Humans; Lung Disea | 1987 |
A randomized, controlled trial of theophylline in patients with severe chronic obstructive pulmonary disease.
Topics: Bronchitis; Carbon Dioxide; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Meth | 1989 |
[Clinico-laboratory evaluation a new sustained-release preparation of anhydrous theophylline].
Topics: Adult; Aged; Asthma; Bronchitis; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obstruc | 1989 |
[Theophylline plus salbutamol in chronic bronchial obstruction. The additive effects of combination therapy in comparison with salbutamol monotherapy].
Topics: Adult; Albuterol; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; | 1989 |
Clinical efficacy of ciprofloxacin in lower respiratory tract infections.
Topics: Ciprofloxacin; Clinical Trials as Topic; Cystic Fibrosis; Drug Interactions; Humans; Lung Diseases, | 1989 |
Theophylline and salbutamol in combination in patients with obstructive pulmonary disease and concurrent heart disease: effect on cardiac arrhythmias.
Topics: Aged; Albuterol; Arrhythmias, Cardiac; Clinical Trials as Topic; Delayed-Action Preparations; Drug T | 1989 |
Treatment of patients with chronic airways obstruction: a controlled study with bamyphylline.
Topics: Adult; Aged; Aged, 80 and over; Auscultation; Blood Gas Analysis; Blood Pressure; Double-Blind Metho | 1989 |
Measuring functional status in chronic lung disease: conclusions from a randomized control trial.
Topics: Albuterol; Analysis of Variance; Drug Therapy, Combination; Exercise Test; Humans; Lung; Lung Diseas | 1989 |
Treatment of reversible chronic airways obstruction with doxofylline compared with slow-release theophylline: a double-blind, randomized, multicentre trial.
Topics: Adolescent; Adult; Aged; Albuterol; Delayed-Action Preparations; Double-Blind Method; Female; Humans | 1989 |
Dose-dependent inhibition of theophylline metabolism by disulfiram in recovering alcoholics.
Topics: Adult; Alcoholism; Disulfiram; Dose-Response Relationship, Drug; Drug Interactions; Half-Life; Human | 1989 |
Chronopharmacodynamics and kinetics after symmetric and asymmetric multiple theophylline doses in patients with chronic obstructive pulmonary disease.
Topics: Absorption; Adult; Aged; Circadian Rhythm; Dose-Response Relationship, Drug; Double-Blind Method; He | 1989 |
Should study subjects see their previous responses: data from a randomized control trial.
Topics: Administration, Oral; Aged; Albuterol; Double-Blind Method; Drug Therapy, Combination; Female; Human | 1989 |
Cardiac arrhythmias in patients with mild-to-moderate obstructive lung disease. Comparison of beta-agonist therapy alone and in combination with a xanthine derivative, enprofylline or theophylline.
Topics: Adrenergic beta-Agonists; Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind | 1985 |
Theophylline as a bronchodilator in COPD and its combination with inhaled beta-adrenergic drugs.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Asthma; Bronchi; Bronchitis; Clinical Trials as Topic; | 1987 |
Ipratropium.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Asthma; Atropine Derivatives; Clinical Trials | 1987 |
A comparative trial of ipratropium bromide (Atrovent), controlled release theophylline (Phyllocontin), and a combination of these in patients with reversible airflow obstruction.
Topics: Adult; Aged; Atropine Derivatives; Clinical Trials as Topic; Delayed-Action Preparations; Double-Bli | 1986 |
Comparison of bronchodilator effects of Duovent and Reproterol in patients with chronic reversible airway obstruction.
Topics: Atropine Derivatives; Clinical Trials as Topic; Drug Combinations; Fenoterol; Forced Expiratory Volu | 1986 |
[Combination of anticholinergic, beta-2-sympathomimetic agents and theophylline in the treatment of chronic obstructive lung disease. A double-blind multicenter study of 60 patients].
Topics: Adult; Aged; Atropine Derivatives; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Comb | 1987 |
[Time-related distribution of delayed-action theophylline in the treatment of chronic obstructive bronchopneumopathies].
Topics: Delayed-Action Preparations; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Random Allocatio | 1988 |
[Use of a new delayed-release anhydrous theophylline by single daily administration in the treatment of reversible bronchial obstruction. Comparison with a delayed-release preparation administered twice daily].
Topics: Adult; Aged; Analysis of Variance; Clinical Trials as Topic; Delayed-Action Preparations; Humans; Lu | 1987 |
Safety and efficacy of once-daily Uniphyl tablets compared with twice-daily Theo-Dur tablets in elderly patients with chronic airflow obstruction.
Topics: Aged; Asthma; Chronic Disease; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind M | 1988 |
Acute response to bronchodilator. An imperfect guide for bronchodilator therapy in chronic airflow limitation.
Topics: Administration, Inhalation; Administration, Oral; Aged; Albuterol; Analysis of Variance; Clinical Tr | 1988 |
[Modification of mucociliary clearance by a combination of theophylline with ambroxol and of ambroxol in monotherapy].
Topics: Adult; Aerosols; Ambroxol; Bromhexine; Clinical Trials as Topic; Double-Blind Method; Humans; Lung D | 1988 |
[Theophylline therapy: patient compliance and dosage. A clinical study].
Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Lung Diseases, Obstructive; Pati | 1988 |
[Increase of arterial oxygen pressure in therapy with theophylline in patients with obstructive ventilation disorder and partial respiratory insufficiency].
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Lung Diseases, Obstructive; Oxygen; Random Al | 1988 |
Theophylline and diaphragmatic contractility. Investigation of a dose-response relationship.
Topics: Clinical Trials as Topic; Diaphragm; Dose-Response Relationship, Drug; Double-Blind Method; Humans; | 1988 |
Dose response relation to oral theophylline in severe chronic obstructive airways disease.
Topics: Administration, Oral; Aged; Dose-Response Relationship, Drug; Exercise; Female; Forced Expiratory Fl | 1988 |
Famotidine effects on theophylline pharmacokinetics in subjects affected by COPD. Comparison with cimetidine and placebo.
Topics: Aged; Cimetidine; Famotidine; Female; Half-Life; Humans; Lung Diseases, Obstructive; Male; Metabolic | 1988 |
Effects of withdrawal of sustained-release theophylline in patients with chronic obstructive lung disease.
Topics: Adult; Aged; Delayed-Action Preparations; Double-Blind Method; Drug Tolerance; Dyspnea; Female; Forc | 1988 |
Effect of inhaled metaproterenol on exercise performance in patients with stable "fixed" airway obstruction.
Topics: Administration, Inhalation; Analysis of Variance; Double-Blind Method; Drug Evaluation; Drug Therapy | 1988 |
Bronchodilator effect and serum theophylline level after combined treatment with fenoterol and theophylline in reversible chronic airflow obstruction.
Topics: Adult; Aged; Bronchodilator Agents; Delayed-Action Preparations; Double-Blind Method; Drug Interacti | 1988 |
The role of theophylline in the treatment of dyspnea in COPD.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Dyspnea; Exercise Test; Forced Expirator | 1987 |
The effects of theophylline on airway inflammation.
Topics: Adult; Animals; Anti-Inflammatory Agents; Asthma; Bronchi; Bronchial Provocation Tests; Bronchitis; | 1987 |
Theophylline and mucociliary clearance.
Topics: Aminophylline; Animals; Asthma; Bronchitis; Cilia; Clinical Trials as Topic; Dogs; Humans; Lung Dise | 1987 |
[Theophylline in the therapy of non reversible airway obstruction].
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Humans; Lung Diseases, Obstructive; Middle Aged; | 1987 |
[Theophylline--once or twice daily?].
Topics: Adult; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Lung Diseases, Obstru | 1987 |
Effect of various disease states on theophylline plasma levels and on pulmonary function in patients with chronic airway obstruction treated with a sustained release theophylline preparation.
Topics: Clinical Trials as Topic; Delayed-Action Preparations; Digestive System Diseases; Heart Diseases; Hu | 1987 |
Unequal twice-daily, sustained-release theophylline dosing in chronic obstructive pulmonary disease.
Topics: Circadian Rhythm; Clinical Trials as Topic; Delayed-Action Preparations; Drug Administration Schedul | 1987 |
[Prescription of Theostat 300 as a single evening dose].
Topics: Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Drug Administration Schedule; Female; | 1987 |
Dyspnea and diaphragmatic fatigue in patients with chronic obstructive pulmonary disease. Responses to theophylline.
Topics: Diaphragm; Dyspnea; Electromyography; Exercise Test; Humans; Lung Diseases, Obstructive; Muscles; Re | 1988 |
The effect of dosing time on the pharmacokinetics and pharmacodynamics of a 'once-a-day' sustained release theophylline preparation.
Topics: Adult; Aged; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; Lung Disease | 1987 |
Compliance measure development and assessment of theophylline therapy in ambulatory patients.
Topics: Adult; Ambulatory Care; Humans; Lung Diseases, Obstructive; Male; Mathematics; Patient Compliance; P | 1987 |
Efficacy of inhaled metaproterenol and orally-administered theophylline in patients with chronic airflow obstruction.
Topics: Administration, Oral; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination | 1986 |
Oxitropium bromide, a new anticholinergic bronchodilator.
Topics: Adult; Blood Pressure; Bronchodilator Agents; Chronic Disease; Clinical Trials as Topic; Dose-Respon | 1986 |
[Therapeutic action of a new xanthine derivative in respiratory pathology].
Topics: Adult; Aged; Bronchodilator Agents; Clinical Trials as Topic; Female; Humans; Lung Diseases, Obstruc | 1986 |
The hemodynamic effects of aminophylline and salbutamol alone and in combination.
Topics: Adult; Albuterol; Aminophylline; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination | 1986 |
[Comparative study of plasma levels of 2 delayed-action theophyllines: Theostat 200 and Theodur 200, after a single evening dose].
Topics: Adult; Asthma; Bronchitis; Delayed-Action Preparations; Double-Blind Method; Drug Administration Sch | 1986 |
Aminophylline for acute exacerbations of chronic obstructive pulmonary disease. A controlled trial.
Topics: Acute Disease; Aged; Aminophylline; Double-Blind Method; Drug Evaluation; Female; Forced Expiratory | 1987 |
Once-daily dosing of a new ultrasustained-release theophylline preparation.
Topics: Aged; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Dose-Response Relationship, | 1987 |
Theophylline clearance in patients with severe chronic obstructive pulmonary disease receiving supplemental oxygen and the effect of acute hypoxemia.
Topics: Administration, Oral; Aged; Humans; Hydrogen-Ion Concentration; Hypoxia; Injections, Intravenous; Lu | 1986 |
[Bronchospasmolytic effectiveness of controlled drug combinations].
Topics: Airway Resistance; Aminophylline; Atropine Derivatives; Blood Pressure; Bronchial Spasm; Bronchodila | 1986 |
The use of sustained-release theophylline ('Theo-dur') for the treatment of chronic reversible obstructive lung disease in hospital practice.
Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Delayed-Action Preparations; Female; Force | 1985 |
Long-term therapy with sustained-release theophylline.
Topics: Adult; Aged; Albuterol; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; | 1985 |
Serum theophylline and ventilatory function in chronic obstructive lung disease. Comparison between two slow-release formulations of theophylline.
Topics: Albuterol; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Human | 1985 |
Sustained-release theophylline reduces dyspnea in nonreversible obstructive airway disease.
Topics: Administration, Oral; Double-Blind Method; Dyspnea; Humans; Lung Diseases, Obstructive; Male; Middle | 1985 |
The efficacy of orally administered theophylline, inhaled salbutamol, and a combination of the two as chronic therapy in the management of chronic bronchitis with reversible air-flow obstruction.
Topics: Administration, Oral; Aerosols; Aged; Albuterol; Bronchitis; Delayed-Action Preparations; Drug Thera | 1985 |
[Improvement of ventilation in patients with restrictive and irreversible obstructive ventilation disorders by a single dose of theophylline].
Topics: Adult; Airway Resistance; Drug Administration Schedule; Female; Humans; Lung Diseases, Obstructive; | 1985 |
Comparison of two sustained-release theophylline preparations in adult patients with obstructive airways disease.
Topics: Adolescent; Adult; Aged; Biological Availability; Delayed-Action Preparations; Humans; Kinetics; Lun | 1985 |
[Pluridirectional treatment of chronic, obstructive bronchopneumopathy with rectal administration of a new drug combination].
Topics: Chronic Disease; Clinical Trials as Topic; Doxylamine; Drug Combinations; Ephedrine; Evaluation Stud | 1972 |
Clinical trial of rapidly dissolving theophylline tablets.
Topics: Clinical Trials as Topic; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Placebos; Solubilit | 1974 |
Slow release salbutamol and Tedral in the treatment of reversible airways obstruction.
Topics: Adolescent; Adult; Aged; Amino Alcohols; Bronchodilator Agents; Clinical Trials as Topic; Delayed-Ac | 1971 |
357 other studies available for theophylline and Obstructive Lung Diseases
| Article | Year |
|---|---|
Selective bilateral hippocampal lesions after theophylline-induced status epilepticus causes a permanent amnesic syndrome.
Topics: Amnesia; Bronchodilator Agents; Hippocampus; Humans; Lung Diseases, Obstructive; Magnetic Resonance | 2011 |
[Comparative studies on the action of aerosol inhalants on broncholysis and oxygen supply in obstructive lung diseases].
Topics: Aerosols; Asthma; Ephedrine; Humans; Lung Diseases; Lung Diseases, Obstructive; Oxygen; Respiratory | 1961 |
[Ambulatory treatment of chronic obstructive lung diseases].
Topics: Adrenergic beta-Agonists; Ambulatory Care; Humans; Lung Diseases, Obstructive; Parasympatholytics; S | 1980 |
Considerations in office management of chronic obstructive pulmonary disease.
Topics: Adrenergic beta-Agonists; Bronchitis; Humans; Lung Diseases, Obstructive; Pulmonary Emphysema; Theop | 1981 |
Cimetidine-theophylline interaction: report of four patients.
Topics: Adrenergic beta-Agonists; Aged; Cimetidine; Drug Interactions; Female; Guanidines; Humans; Lung Dise | 1982 |
Important aspects of pulmonary rehabilitation.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Bronchitis; Community Health Nursing; Drug Therap | 1982 |
[Longterm treatment in chronic nonspecific airway diseases (author's transl)].
Topics: Adrenergic beta-Antagonists; Anti-Bacterial Agents; Bromhexine; Bronchi; Bronchial Spasm; Humans; Lu | 1982 |
[Recommendations for a graduated system of long-term drug therapy of obstructive respiratory tract diseases].
Topics: Adrenergic beta-Agonists; Anti-Bacterial Agents; Glucocorticoids; Humans; Long-Term Care; Lung Disea | 1984 |
[Drug treatment of children with CARA].
Topics: Adrenergic beta-Agonists; Asthma; Child; Child, Preschool; Cromolyn Sodium; Glucocorticoids; Humans; | 1983 |
Bronchodilator therapy in chronic airflow obstruction.
Topics: Adrenergic beta-Agonists; Bronchodilator Agents; Humans; Ipratropium; Lung Diseases, Obstructive; Me | 1984 |
[Evaluation using dynamic ECG of the effects of reproterol (a new beta-2 adrenergic receptor agonist) on the heart conduction system].
Topics: Adrenergic beta-Agonists; Adult; Aged; Bronchodilator Agents; Drug Combinations; Drug Evaluation; El | 1984 |
[The renaissance of theophylline therapy].
Topics: Calcium; Cyclic AMP; Cyclic GMP; Delayed-Action Preparations; Humans; Lung Diseases, Obstructive; Ma | 1982 |
Pharmacokinetics and pharmacodynamics of a short- and long-acting theophylline medication (Theolair and Theolair retard) in normals and patients with COLD. Part III: Plasma cyclic AMP.
Topics: Adult; Cyclic AMP; Delayed-Action Preparations; Humans; Lung; Lung Diseases, Obstructive; Middle Age | 1983 |
Pharmacokinetics of theophylline and the H2-antagonist drugs cimetidine and ranitidine.
Topics: Adult; Aged; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Half-Life; Humans; Lun | 1984 |
Influence of medroxyprogesterone on theophylline disposition.
Topics: Aged; Carbon Dioxide; Drug Interactions; Female; Forced Expiratory Volume; Humans; Kinetics; Lung Di | 1983 |
[Possibilities for optimizing therapy with theophylline preparations. Clinical effectiveness and side effects of microcrystalline theophylline].
Topics: Adult; Asthma; Female; Forced Expiratory Volume; Humans; Kinetics; Long-Term Care; Lung Diseases, Ob | 1984 |
Clinical results obtained from a new controlled release theophylline preparation.
Topics: Adolescent; Adult; Aged; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obstructive; Ma | 1984 |
The tolerability of a new oral controlled release theophylline preparation in patients with obstructive airways diseases.
Topics: Adolescent; Adult; Aged; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obstructive; Ma | 1984 |
How many plasma theophylline levels are needed to control therapy?
Topics: Humans; Lung Diseases, Obstructive; Theophylline | 1984 |
Doses of aminophylline given intravenously in casualty department and resulting serum theophylline concentrations.
Topics: Aged; Aminophylline; Asthma; Emergencies; Emergency Service, Hospital; England; Female; Humans; Inje | 1984 |
Short-acting versus a long-acting preparation of theophylline ('Xantivent') in the treatment of reversible bronchospasm.
Topics: Adolescent; Adult; Bronchial Spasm; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obst | 1984 |
Serum theophylline levels with oral sustained release theophylline after transfer from intravenous aminophylline in patients with chronic lung disease.
Topics: Aged; Aminophylline; Delayed-Action Preparations; Humans; Lung Diseases, Obstructive; Male; Middle A | 1984 |
The influence of orally administered cimetidine and theophylline on the elimination of each drug in patients with chronic airways obstruction.
Topics: Age Factors; Aged; Bronchodilator Agents; Choline; Cimetidine; Drug Interactions; Half-Life; Humans; | 1984 |
Theophylline and chronic obstructive pulmonary disease.
Topics: Humans; Lung Diseases, Obstructive; Theophylline | 1984 |
Dose-dependent kinetics of theophylline in adults with pulmonary diseases.
Topics: Adult; Aged; Aminophylline; Asthma; Dose-Response Relationship, Drug; Female; Humans; Infusions, Par | 1984 |
Comment on COAD.
Topics: Acute Disease; Humans; Lung Diseases, Obstructive; Theophylline | 1984 |
[A single dose of theophylline in the evening in chronic obstructive airway disease. Serum concentration and lung function parameter].
Topics: Adult; Airway Resistance; Drug Administration Schedule; Female; Humans; Kinetics; Lung Diseases, Obs | 1984 |
[Detection of theophylline in human serum and its clinical application].
Topics: Adolescent; Adult; Aged; Female; Humans; Kinetics; Lung Diseases, Obstructive; Male; Middle Aged; Th | 1984 |
Effects of theophylline-ethylendiamine on chronic pulmonary arterial hypertension secondary to chronic obstructive pulmonary disease.
Topics: Blood Pressure; Drug Combinations; Ethylenediamines; Heart; Humans; Hypertension, Pulmonary; Injecti | 1984 |
Theophylline therapy in COAD.
Topics: Humans; Lung Diseases, Obstructive; Theophylline | 1983 |
A new spirometric parameter in clinical pharmacology.
Topics: Blood Gas Analysis; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Maxi | 1983 |
Prescribing habits for theophylline preparations.
Topics: Adolescent; Adult; Aged; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; | 1983 |
Prediction of maintenance oral theophylline dosage using single oral doses in patients with obstructive airways disease.
Topics: Administration, Oral; Adult; Aged; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Th | 1983 |
Study of the effect of small dose of steroid to ephedrine--theophylline combination in chronic obstructive pulmonary disease.
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ephedrine; Female; H | 1983 |
Influenza vaccination and theophylline pharmacokinetics in patients with chronic obstructive lung disease.
Topics: Aged; Humans; Influenza Vaccines; Kinetics; Lung Diseases, Obstructive; Male; Metabolic Clearance Ra | 1983 |
Prediction of serum theophylline levels.
Topics: Adolescent; Adult; Aged; Asthma; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Theo | 1984 |
Patient compliance with oral theophylline therapy.
Topics: Adult; Aged; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obstructive; Male; Middle A | 1984 |
Cimetidine-theophylline interaction in patients with chronic obstructive airways disease.
Topics: Aged; Cimetidine; Drug Interactions; Female; Humans; Kinetics; Lung Diseases, Obstructive; Middle Ag | 1984 |
Asthma and irreversible airflow obstruction.
Topics: Adult; Age Factors; Albuterol; Asthma; Chronic Disease; Female; Forced Expiratory Volume; Humans; Lu | 1984 |
[Hemodynamics of pulmonary circulation in patients with chronic obstructive lung disease and pulmonary hypertension as dependent on the theophylline concentration of the serum].
Topics: Aged; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Middle Aged; Pulmonary Circ | 1984 |
[Choice of bronchodilators].
Topics: Adrenal Cortex Hormones; Asthma; Bronchodilator Agents; Humans; Lung Diseases, Obstructive; Muscle T | 1984 |
Oral theophylline intoxication. A serious error of patient and physician understanding.
Topics: Aged; Alkaline Phosphatase; Charcoal; Dose-Response Relationship, Drug; Drug Interactions; Electroca | 1984 |
Pharmacologic management of chronic obstructive pulmonary disease.
Topics: Aged; Anti-Bacterial Agents; Bronchodilator Agents; Female; Humans; Hypertension, Pulmonary; Lung Di | 1984 |
[Possibilities for optimizing therapy with theophylline preparations. III. Ventilatory effect and pharmacokinetics of "new" Pulmophyllin].
Topics: Adult; Aminophylline; Antipyrine; Asthma; Double-Blind Method; Drug Combinations; Female; Forced Exp | 1984 |
[Possibilities for optimizing therapy with theophylline preparations. I. On the pharmacokinetics of theophylline preparations].
Topics: Adult; Aminophylline; Asthma; Biological Availability; Delayed-Action Preparations; Female; Humans; | 1984 |
Theophylline clearance. Lack of effect of influenza vaccination and ascorbic acid.
Topics: Adult; Aged; Ascorbic Acid; Drug Therapy, Combination; Female; Half-Life; Humans; Influenza Vaccines | 1984 |
Theophylline therapy. Titrating dosage requirements.
Topics: Administration, Oral; Adolescent; Age Factors; Asthma; Cardiovascular Diseases; Child; Child, Presch | 1984 |
Outpatient theophylline determinations.
Topics: Adult; Aged; Ambulatory Care; Bronchial Spasm; Humans; Lung Diseases, Obstructive; Middle Aged; Theo | 1984 |
Free and total plasma theophylline concentrations in chronic airflow obstruction.
Topics: Adolescent; Adult; Aged; Fatty Acids, Nonesterified; Female; Humans; Lung Diseases, Obstructive; Mal | 1984 |
Circadian variation in plasma theophylline concentrations during maintenance therapy with a sustained-release preparation in patients with obstructive airways disease.
Topics: Aged; Circadian Rhythm; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obstructive; Mal | 1984 |
The place for albuterol aerosol in chronic obstructive airway disease: maximizing its use.
Topics: Aerosols; Albuterol; Cromolyn Sodium; Drug Synergism; Humans; Lung Diseases, Obstructive; Respirator | 1981 |
Life-threatening theophylline intoxication in a hypothyroid patient.
Topics: Aged; Dyspnea; Half-Life; Heart Failure; Humans; Hypothyroidism; Lung Diseases, Obstructive; Male; T | 1983 |
Improving patients with advanced chronic airflow obstruction.
Topics: Adrenal Cortex Hormones; Bronchodilator Agents; Forced Expiratory Volume; Humans; Isoproterenol; Lun | 1983 |
[Use of bronchodilators in the therapy of obstructive respiratory diseases].
Topics: Aerosols; Asthma; Atropine Derivatives; Bronchitis; Bronchodilator Agents; Humans; Lung Diseases, Ob | 1983 |
Cimetidine inhibits theophylline clearance in patients with chronic obstructive pulmonary disease: a study using stable isotope methodology during multiple oral dose administration.
Topics: Administration, Oral; Aged; Carbon Isotopes; Cimetidine; Drug Interactions; Guanidines; Humans; Lung | 1983 |
Monitoring aminophylline therapy using Jusko's dosage guidelines.
Topics: Adult; Aged; Aminophylline; Humans; Lung Diseases, Obstructive; Middle Aged; Theophylline | 1983 |
Chronic airflow obstruction. Two-pronged approach to outpatient management.
Topics: Adrenal Cortex Hormones; Bronchodilator Agents; Humans; Lung Diseases, Obstructive; Motivation; Smok | 1983 |
Effect of erythromycin stearate on serum theophylline concentration in patients with chronic obstructive lung disease.
Topics: Administration, Oral; Aged; Erythromycin; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Pro | 1983 |
Decrease in theophylline clearance after the administration of erythromycin to a patient with obstructive lung disease.
Topics: Aged; Drug Interactions; Erythromycin; Humans; Lung Diseases, Obstructive; Male; Metabolic Clearance | 1983 |
Lack of dose dependent kinetics of theophylline.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Lung Diseases, Obstructive; | 1983 |
The effect of aminophylline on cardiac rhythm in advanced chronic obstructive pulmonary disease: correlation with serum theophylline levels.
Topics: Aged; Aminophylline; Arrhythmias, Cardiac; Heart Rate; Heart Ventricles; Humans; Lung Diseases, Obst | 1983 |
[Optimizing of therapy with theophylline preparations in obstructive respiratory diseases. 4. Effect of theophylline on mucociliary clearance and maximal inspiratory mouth occlusion pressure].
Topics: Adult; Aged; Cilia; Female; Humans; Lung; Lung Diseases, Obstructive; Male; Metabolic Clearance Rate | 1983 |
Prediction of optimum oral theophylline dose in patients with obstructive airways disease.
Topics: Adult; Aged; Asthma; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Models, Biologic | 1983 |
[Tolerance of a new oral long-acting theophylline in patients with obstructive airway diseases].
Topics: Administration, Oral; Adult; Aged; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obstr | 1983 |
[Obstructive airway diseases in children].
Topics: Abscess; Adult; Asthma; Child; Child, Preschool; Cystic Fibrosis; Foreign-Body Reaction; Humans; Inh | 1982 |
Concurrent use of theophylline and lithium in a patient with chronic obstructive lung disease and bipolar disorder.
Topics: Aged; Bipolar Disorder; Drug Interactions; Humans; Lithium; Lung Diseases, Obstructive; Male; Theoph | 1982 |
Plasma theophylline concentrations in patients with chronic obstructive airways disease after administration of a new sustained release theophylline formulation.
Topics: Aged; Delayed-Action Preparations; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstruct | 1982 |
[Measure out oral theophylline exactly. Also determine theophylline levels in clinical practice].
Topics: Aerosols; Dose-Response Relationship, Drug; Humans; Lung Diseases, Obstructive; Theophylline | 1982 |
Theophylline kinetics and ventilatory flow in bronchial asthma and chronic airflow obstruction: influence of erythromycin.
Topics: Adult; Aged; Asthma; Drug Interactions; Drug Therapy, Combination; Erythromycin; Female; Humans; Kin | 1982 |
The use of theophylline clearance to design an oral aminophylline regimen.
Topics: Administration, Oral; Adult; Aged; Aminophylline; Asthma; Body Weight; Female; Humans; Kinetics; Lun | 1982 |
[Biological availability of two theophylline preparations (author's transl)].
Topics: Administration, Oral; Biological Availability; Delayed-Action Preparations; Humans; Lung Diseases, O | 1982 |
[Treatment of obstructive respiratory disorders using a new theophylline retard preparation].
Topics: Airway Resistance; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obstructive; Male; Mi | 1982 |
The influence of theophylline on maximal response to salbutamol in severe chronic obstructive pulmonary disease.
Topics: Aged; Albuterol; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Forced Expirat | 1982 |
Stable isotope methodology in a pharmacokinetic study of the interaction of theophylline and cimetidine.
Topics: Carbon Isotopes; Chromatography, High Pressure Liquid; Chronic Disease; Cimetidine; Drug Interaction | 1982 |
Management of respiratory problems in the aged.
Topics: Aged; Asthma; Common Cold; Cough; Expectorants; Glucocorticoids; Humans; Lung Diseases, Obstructive; | 1982 |
Improvement in cardiac performance by oral long-acting theophylline in chronic obstructive pulmonary disease.
Topics: Administration, Oral; Aged; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; Lung Diseases, | 1982 |
[Therapy using delayed-action theophylline].
Topics: Aerosols; Blood Pressure; Delayed-Action Preparations; Heart Rate; Humans; Lung Diseases, Obstructiv | 1982 |
[Use of theophylline in severe bronchospasm states].
Topics: Adult; Aged; Bronchial Spasm; Female; Humans; Infusions, Parenteral; Lung Diseases, Obstructive; Mal | 1982 |
[Theophylline therapy in obstructive respiratory diseases. 1. Bioavailability and pharmacokinetics of various theophylline preparations (author's transl)].
Topics: Adult; Aged; Biological Availability; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; | 1981 |
Maintenance oral theophylline therapy: suggested schedule in elderly patients.
Topics: Administration, Oral; Aged; Asthma; Chronic Disease; Drug Administration Schedule; Female; Humans; I | 1980 |
Theophylline serum protein binding in obstructive airways disease.
Topics: Adult; Age Factors; Aged; Blood Proteins; Child; Female; Humans; Lung Diseases, Obstructive; Male; M | 1981 |
[Therapy of chronic obstructive respiratory syndrome with the new theophylline preparation Afonilum retard].
Topics: Asthma; Bronchitis; Chronic Disease; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obs | 1981 |
[Is there a renaissance of oral theophylline therapy in chronic obstructive airway syndrome?].
Topics: Administration, Oral; Female; Humans; Lung Diseases, Obstructive; Lung Volume Measurements; Male; Mi | 1981 |
Pharmacokinetics of a single evening dose of slow release theophylline in patients with chronic lung disease.
Topics: Aged; Delayed-Action Preparations; Humans; Kinetics; Lung Diseases, Obstructive; Male; Middle Aged; | 1981 |
[Application of theophylline as an inhalant (author's transl)].
Topics: Adult; Aerosols; Aged; Aminophylline; Humans; Lung Diseases, Obstructive; Middle Aged; Respiratory T | 1981 |
Evaluation of the ordering of serum theophylline concentrations.
Topics: Evaluation Studies as Topic; Hospitals; Humans; Infusions, Parenteral; Lung Diseases, Obstructive; T | 1981 |
[Efficacy of theophylline aerosols in obstructive lung diseases (author's transl)].
Topics: Adult; Aerosols; Aged; Aminophylline; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; | 1981 |
Individualization of oral theophylline dosage in elderly patients.
Topics: Administration, Oral; Age Factors; Aged; Dose-Response Relationship, Drug; Female; Humans; Lung Dise | 1981 |
Evaluation of two methods for estimating theophylline clearance prior to achieving steady state.
Topics: Aminophylline; Asthma; Evaluation Studies as Topic; Half-Life; Humans; Lung Diseases, Obstructive; M | 1981 |
[Microcrystallinic theophylline, plasma concentration and adverse effects in patients with obstructive lung disease].
Topics: Aged; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Theophylline | 1981 |
[Testing of lung function after theophylline inhalation (author's transl)].
Topics: Aerosols; Humans; Lung Diseases, Obstructive; Male; Respiratory Function Tests; Theophylline | 1981 |
[The hemodynamic effects of reproterol in patients with chronic obstructive lung disease (author's transl)].
Topics: Adult; Aged; Bronchodilator Agents; Drug Combinations; Female; Hemodynamics; Humans; Lung Diseases, | 1981 |
Concentration of theophylline on acidemic patients.
Topics: Acidosis; Humans; Hydrogen-Ion Concentration; Lung Diseases, Obstructive; Theophylline | 1980 |
[Effect of theophylline-ethylenediamine in obstructive lung disease (author's transl)].
Topics: Adolescent; Adult; Aged; Airway Resistance; Asthma; Blood Pressure; Bronchitis; Female; Humans; Lung | 1980 |
[Use of theophylline and proxyphylline in the treatment of obstructive lung diseases in children: demands for new dosage routines].
Topics: Administration, Oral; Child; Child, Preschool; Half-Life; Humans; Injections, Intravenous; Lung Dise | 1980 |
[Theophyllin-dosage in adults; blood level determination as therapeutic control].
Topics: Adult; Aged; Drug Interactions; Half-Life; Humans; Kinetics; Lung Diseases, Obstructive; Middle Aged | 1980 |
[Long-term therapy with a peroral effective theophyllin compound (author's transl)].
Topics: Adult; Aged; Asthma; Bronchitis; Drug Tolerance; Emphysema; Female; Humans; Lung Diseases, Obstructi | 1980 |
[Effectiveness of proxyphylline in chronic obstructive pulmonary disease (author's transl)].
Topics: Adult; Aged; Aminophylline; Bronchospirometry; Humans; Lung Diseases, Obstructive; Male; Middle Aged | 1980 |
Disposition and clinical pharmacokinetics of microcrystalline theophylline.
Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Female; Humans; Lung Diseases, Obs | 1980 |
Serum level monitoring of a new slow release theophylline formulation in patients with chronic lung disease.
Topics: Aged; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Th | 1980 |
[New developments in the field of bronchospasmolytics].
Topics: Albuterol; Aminophylline; Bronchial Spasm; Bronchodilator Agents; Clenbuterol; Fenoterol; Glucocorti | 1980 |
[Kombipek in the therapy of patients with broncho-obstructive lung diseases].
Topics: Adult; Albuterol; Bronchodilator Agents; Delayed-Action Preparations; Drug Combinations; Drug Evalua | 1995 |
Aminophylline induced atrial fibrillation.
Topics: Aged; Atrial Fibrillation; Female; Humans; Infusions, Intravenous; Lung Diseases, Obstructive; Male; | 1993 |
Defusing status epilepticus.
Topics: Blood Gas Analysis; Body Temperature; Diazepam; Humans; Infusions, Intravenous; Lung Diseases, Obstr | 1995 |
[Drug monitoring: theophylline--comparison of 3 methods for determination].
Topics: Adult; Aged; Drug Interactions; Drug Monitoring; Female; Humans; Lung Diseases, Obstructive; Male; M | 1995 |
Changing practices in COPD. A new pharmacologic treatment algorithm.
Topics: Administration, Inhalation; Albuterol; Algorithms; Bronchodilator Agents; Drug Administration Schedu | 1995 |
[Long-term therapy with a retard theophylline preparation].
Topics: Delayed-Action Preparations; Female; Forced Expiratory Volume; Humans; Long-Term Care; Lung Diseases | 1995 |
The position of theophylline in the treatment of asthma and chronic obstructive pulmonary disease.
Topics: Acute Disease; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Animals; Asthma; Bronchodil | 1995 |
The clinical implication of theophylline intoxication in the Emergency Department.
Topics: Aged; Analysis of Variance; Arrhythmias, Cardiac; Asthma; Creatine Kinase; Digestive System; Dose-Re | 1994 |
Bronchodilators in COPD.
Topics: Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Respiratory Function Tests; Theophylli | 1994 |
Mild theophylline-related adverse reactions and serum theophylline concentration.
Topics: Adverse Drug Reaction Reporting Systems; Drug Monitoring; Humans; Interviews as Topic; Lung Diseases | 1994 |
Which of the following statements about the use of specific therapies in the treatment of chronic obstructive pulmonary disease are true?
Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Humans; Lung Diseases, Obstructive; Oxygen Inh | 1993 |
What role for theophylline?
Topics: Adrenergic beta-Agonists; Asthma; Bronchial Spasm; Humans; Lung Diseases, Obstructive; Respiratory M | 1994 |
Theophylline.
Topics: Asthma; Hospitalization; Humans; Lung Diseases, Obstructive; Theophylline | 1994 |
Toxic effects of theophylline caused by fluvoxamine.
Topics: Aged; Drug Interactions; Female; Fluvoxamine; Humans; Lung Diseases, Obstructive; Nausea; Theophylli | 1994 |
A warning on the use of Cipro.
Topics: Aged; Ciprofloxacin; Drug Interactions; Humans; Lung Diseases, Obstructive; Theophylline | 1994 |
Twitch potentiating effects of theophylline on rat diaphragm are enhanced by foreshortening.
Topics: Animals; Diaphragm; Lung Diseases, Obstructive; Male; Muscle Contraction; Rats; Rats, Wistar; Respir | 1994 |
Chronic respiratory failure in COPD: is there a place for a respiratory stimulant?
Topics: Almitrine; Antidepressive Agents, Tricyclic; Carbonic Anhydrase Inhibitors; Chronic Disease; Humans; | 1993 |
Steady-state pharmacokinetics of theophylline in COPD patients treated with dirithromycin.
Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Delayed-Action Preparations; Drug Administration | 1993 |
Electroconvulsive therapy in patients taking theophylline.
Topics: Adult; Aged; Asthma; Bronchitis; Chronic Disease; Comorbidity; Depressive Disorder; Electroconvulsiv | 1993 |
[Effects of theophylline on ventilatory regulation in patients with chronic obstructive pulmonary disease].
Topics: Administration, Oral; Adult; Asthma; Blood Gas Analysis; Emphysema; Humans; Lung Diseases, Obstructi | 1993 |
Interaction between drugs and lung immune defences in COPD: local evaluation with bronchoalveolar lavage.
Topics: Acetylcysteine; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Humans; | 1993 |
Effect of aminophylline on brain tissue oxygenation in patients with chronic obstructive lung disease.
Topics: Adult; Aminophylline; Brain; Child; Child Behavior; Humans; Lung Diseases, Obstructive; Oxygen; Theo | 1993 |
[Diagnostic errors in dyspnea].
Topics: Adenocarcinoma, Mucinous; Adult; alpha 1-Antitrypsin Deficiency; Diagnostic Errors; Dyspnea; Heart F | 1993 |
Comparative cost-effectiveness analysis of theophylline and ipratropium bromide in chronic obstructive pulmonary disease. A three-center study.
Topics: Aged; Analysis of Variance; California; Chi-Square Distribution; Cost of Illness; Cost-Benefit Analy | 1993 |
[Theophylline-induced convulsions].
Topics: Aged; Humans; Lung Diseases, Obstructive; Male; Poisoning; Seizures; Theophylline | 1993 |
Monitoring theophylline treatment.
Topics: Dose-Response Relationship, Drug; Humans; Lung Diseases, Obstructive; Reference Values; Theophylline | 1993 |
Famotidine and theophylline pharmacokinetics. An unexpected cimetidine-like interaction in patients with chronic obstructive pulmonary disease.
Topics: Cimetidine; Drug Interactions; Famotidine; Humans; Infusions, Intravenous; Lung Diseases, Obstructiv | 1993 |
Respiratory failure following adenosine administration.
Topics: Adenosine; Contraindications; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Respiratory Ins | 1993 |
[Toxic dermatitis induced by bamifylline. 2 cases].
Topics: Aged; Asthma; Bronchodilator Agents; Dermatitis, Exfoliative; Drug Eruptions; Exanthema; Female; Hum | 1993 |
[Is routine monitoring of theophylline blood levels really effective?].
Topics: Asthma; Bronchodilator Agents; Diagnostic Tests, Routine; Drug Monitoring; Humans; Lung Diseases, Ob | 1995 |
Theophylline-ranitidine interaction in elderly COPD patients.
Topics: Age Factors; Aged; Drug Interactions; Drug Therapy, Combination; Histamine H2 Antagonists; Humans; L | 1995 |
Theophylline: taking it to a new level.
Topics: Bronchodilator Agents; Drug Administration Schedule; Humans; Lung Diseases, Obstructive; Theophyllin | 1996 |
Monitoring theophylline therapy to prevent toxicity.
Topics: Adverse Drug Reaction Reporting Systems; Drug Utilization; Education, Medical, Continuing; Hospitals | 1996 |
N of 1 trials. Research is needed into why such trials are not more widely used.
Topics: Bias; Cross-Over Studies; Humans; Lung Diseases, Obstructive; Randomized Controlled Trials as Topic; | 1996 |
Proceedings of the Theophylline Forum. Stockholm, 25 June 1994.
Topics: Asthma; Bronchodilator Agents; Humans; Lung Diseases, Obstructive; Theophylline | 1996 |
[Practicability, effectiveness and tolerance of a standardized prepared theophylline infusion].
Topics: Adult; Aged; Asthma; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Forced | 1996 |
[Use of Unilair in general practice conditions. Treatment of chronic obstructive airway diseases with theophylline].
Topics: Adult; Aged; Airway Resistance; Bronchodilator Agents; Delayed-Action Preparations; Dose-Response Re | 1997 |
[The pharmacokinetic characteristics of theophylline in patients with chronic nonspecific intestinal diseases in relation to its routes of administration into the gastrointestinal tract].
Topics: Administration, Rectal; Adolescent; Adult; Aged; Aminophylline; Chronic Disease; Digestive System; F | 1993 |
Effect of theophylline on erythrocytosis in chronic obstructive pulmonary disease.
Topics: Adult; Aged; Bronchodilator Agents; Female; Hematocrit; Humans; Lung Diseases, Obstructive; Male; Mi | 1997 |
[The relationships between the broncholytic and diuretic effects of theophylline in patients with obstructive lung diseases combined with oxalosis].
Topics: Bronchodilator Agents; Diuresis; Diuretics; Drug Evaluation; Female; Humans; Hyperoxaluria, Primary; | 1997 |
Fluvoxamine-induced theophylline toxicity.
Topics: Adult; Comorbidity; Depressive Disorder; Drug Interactions; Female; Fluvoxamine; Half-Life; Health C | 1997 |
[Respiratory medicine in the aged. Therapeutic problemsd].
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Aged; Aged, 80 and over; Anti-Bacterial Agents; A | 1997 |
[Subnormal vitamin B6 levels in theophylline users].
Topics: Aged; Aged, 80 and over; Drug Antagonism; Humans; Lung Diseases, Obstructive; Middle Aged; Pyridoxal | 1997 |
Adenosine is worth trying in patients with paroxysmal supraventricular tachycardia on chronic theophylline medication.
Topics: Adenosine; Aged; Bronchodilator Agents; Drug Interactions; Humans; Lung Diseases, Obstructive; Male; | 1998 |
Risk of emergency care, hospitalization, and ICU stays for acute asthma among recipients of salmeterol.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Age Factors; Albuterol; Anti-Asthmatic Agents; Asthma; | 1998 |
Theophylline-induced stuttering.
Topics: Aged; Bronchodilator Agents; Drug Therapy, Combination; Humans; Lung Diseases, Obstructive; Male; St | 1998 |
Analysis of inhaled corticosteroid and oral theophylline use among patients with stable COPD from 1987 to 1995.
Topics: Administration, Inhalation; Administration, Oral; Aged; Bronchodilator Agents; Clinical Trials as To | 1999 |
Dealing with DRGs: analysis of serum theophylline assays in Medicare patients.
Topics: Diagnosis-Related Groups; Drug Utilization; Hospital Bed Capacity, 500 and over; Lung Diseases, Obst | 1986 |
Maintenance drug therapy of chronic obstructive pulmonary disease.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Drug Therapy; Education, Pharmacy, Continuing; Hu | 1999 |
[Population pharmacokinetic analysis of theophylline: relationship between serum concentrations and clinical effects in therapeutic drug monitoring].
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Biological Availability; B | 1999 |
Increased resting energy expenditure is related to plasma TNF-alpha concentration in stable COPD patients.
Topics: Basal Metabolism; Body Composition; Bronchodilator Agents; Female; Humans; Interleukin-1; Interleuki | 1999 |
The reality of drug use in COPD: the European perspective.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Aged; Cholinergic Antagonists; Cross-Cultural C | 2000 |
High-performance thin-layer chromatographic determination of theophylline in plasma.
Topics: Bronchodilator Agents; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Humans; Ki | 1999 |
Evidence of oxidative stress in asthma and COPD: potential inhibitory effect of theophylline.
Topics: Aged; Asthma; Female; Forced Expiratory Volume; Humans; Lipid Peroxides; Lung Diseases, Obstructive; | 2000 |
Optimizing bronchodilator therapy for copd.
Topics: Albuterol; Bronchodilator Agents; Humans; Lung Diseases, Obstructive; Salmeterol Xinafoate; Theophyl | 2001 |
Differential inhibition of equine neutrophil function by phosphodiesterase inhibitors.
Topics: Animals; Cell Adhesion; Cells, Cultured; Horse Diseases; Horses; Lung Diseases, Obstructive; Neutrop | 2001 |
Choosing a drug regimen for obstructive pulmonary disease. 1. Agents to achieve bronchodilatation.
Topics: Administration, Oral; Adrenergic beta-Agonists; Aerosols; Bronchodilator Agents; Humans; Injections, | 1978 |
Kinetics of theophylline; variability and effect of arterial pH in chronic obstructive lung disease.
Topics: Aged; Aminophylline; Female; Half-Life; Humans; Hydrogen-Ion Concentration; Infusions, Parenteral; L | 1979 |
[The effect of fominoben and oxyethyltheophylline in combination on pulmonary function and pulmonary hemodynamics in chronic-obstructive diseases of the airways (author's transl)].
Topics: Chronic Disease; Drug Combinations; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; M | 1978 |
Myths, morbidity, and mortality in asthma.
Topics: Acidosis, Respiratory; Adrenal Cortex Hormones; Asthma; Humans; Intermittent Positive-Pressure Breat | 1979 |
[Obstructive lung diseases. Efficient therapy using Phyllotemp retard].
Topics: Adult; Delayed-Action Preparations; Drug Combinations; Ethylenediamines; Female; Humans; Lung Diseas | 1979 |
[Changes in the acid-base equilibrium and the water-electrolyte balance during maximum aerobic work in patients with chronic broncho-pulmonary disease].
Topics: Acid-Base Equilibrium; Bicarbonates; Ethylenediamines; Humans; Lung Diseases, Obstructive; Oxygen In | 1979 |
Comparison of standard- and sustained-release theophylline tablets in patients with chronic obstructive pulmonary disease.
Topics: Adult; Aminophylline; Delayed-Action Preparations; Female; Humans; Kinetics; Lung Diseases, Obstruct | 1979 |
[Why is Etaphylline not better in chronic aspecific respiratory disease?].
Topics: Administration, Oral; Bronchodilator Agents; Half-Life; Humans; Intestinal Absorption; Lung Diseases | 1979 |
Oral aminophylline therapy. Increased dosage requirements in children.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Aminophylline; Asthma; Child; Child, Pre | 1977 |
Effects of aminophylline upon right and left ventricular performance in chronic obstructive pulmonary disease: noninvasive assessment by radionuclide angiocardiography.
Topics: Adult; Aged; Aminophylline; Angiocardiography; Carbon Dioxide; Cardiac Output; Chronic Disease; Fema | 1978 |
Impaired theophylline clearance in patients with cor pulmonale.
Topics: Administration, Oral; Female; Humans; Injections, Intravenous; Lung Diseases, Obstructive; Male; Mid | 1979 |
Theophylline, a review.
Topics: Aminophylline; Asthma; Bronchial Spasm; Dose-Response Relationship, Drug; Humans; Lung Diseases, Obs | 1977 |
[Theophylline blood levels after administration of Euphyllin retard (author's transl)].
Topics: Adolescent; Adult; Aged; Airway Resistance; Aminophylline; Half-Life; Humans; Lung Diseases, Obstruc | 1977 |
Unpredictability of theophylline saliva measurements in chronic obstructive pulmonary disease.
Topics: Chronic Disease; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Saliva; Theophylline | 1977 |
Clinical experience with theophylline. Relarionships between dosage, serum concentration, and toxicity.
Topics: Administration, Oral; Adult; Aged; Diarrhea; Female; Humans; Injections, Intravenous; Kinetics; Lung | 1976 |
Rehabilitation of patients with chronic obstructive pulmonary disease.
Topics: Adrenal Cortex Hormones; Airway Resistance; Atropine; Bacterial Infections; Follow-Up Studies; Healt | 1976 |
Effect of bronchodilator agents on arrhythmia.
Topics: Arrhythmias, Cardiac; Bronchodilator Agents; Humans; Isoproterenol; Lung Diseases, Obstructive; Theo | 1976 |
[Broncholytic effect of Atrovent in comparison with a combination preparation in obstructive lung diseases].
Topics: Adult; Aged; Atropa belladonna; Atropine; Bronchodilator Agents; Caffeine; Drug Combinations; Ephedr | 1975 |
Plasma theophylline level and ventilatory function in chronic obstructive pulmonary disease during prolonged oral treatment with choline theophyllinate.
Topics: Adult; Aged; Choline; Drug Administration Schedule; Female; Forced Expiratory Volume; Humans; Lung D | 1975 |
Experiences with various preparations of ephedrine theophylline combination in chronic obstructive pulmonary disease.
Topics: Chronic Disease; Drug Therapy, Combination; Ephedrine; Humans; Lung Diseases, Obstructive; Theophyll | 1976 |
[Effects of theophylline on the respiratory system].
Topics: Animals; Asthma; Bronchodilator Agents; Cardiovascular System; Diaphragm; Histamine Release; Humans; | 1992 |
Criteria for use of theophylline (aminophylline) in inpatients and outpatients with pulmonary disease.
Topics: Ambulatory Care; Asthma; Drug Utilization; Hospitalization; Humans; Lung Diseases, Obstructive; Theo | 1992 |
Intravenous therapy of chronic obstructive pulmonary disease with sodium glycinate theophylline monitored by a new bed side theophylline assay.
Topics: Aged; Chromatography; Drug Monitoring; Female; Humans; Infusions, Intravenous; Lung Diseases, Obstru | 1992 |
Drug treatment of COPD. Controversies about agents and how to deliver them.
Topics: Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta-Agonists; | 1992 |
[A comparison of bronchodilating drugs in the treatment of stable COPD].
Topics: Administration, Inhalation; Administration, Oral; Albuterol; Bronchodilator Agents; Forced Expirator | 1992 |
[Relationship among dosages of aminophylline, plasma levels of theophylline and variation of pulmonary arterial pressure].
Topics: Adult; Aged; Aged, 80 and over; Aminophylline; Blood Pressure; Female; Humans; Lung Diseases, Obstru | 1992 |
Elevation of serum theophylline levels by ipriflavone in a patient with chronic obstructive pulmonary disease.
Topics: Aged; Drug Interactions; Humans; Isoflavones; Lung Diseases, Obstructive; Male; Theophylline | 1992 |
Theophylline-mexiletine interaction: a case report.
Topics: Aged; Delayed-Action Preparations; Drug Interactions; Humans; Lung Diseases, Obstructive; Male; Mexi | 1992 |
[Therapeutic non-compliance with theophylline preparations in ambulatory treatment].
Topics: Adult; Ambulatory Care; Asthma; Child; Female; Humans; Lung Diseases, Obstructive; Male; Patient Com | 1992 |
Theophylline toxicity after propafenone treatment: evidence for drug interaction.
Topics: Aged; Drug Interactions; Humans; Lung Diseases, Obstructive; Male; Propafenone; Theophylline | 1992 |
[Principles of theophylline therapy in obstructive respiratory diseases].
Topics: Asthma; Humans; Lung Diseases, Obstructive; Theophylline | 1992 |
The effects of inhaled albuterol and oral theophylline on gastroesophageal reflux in patients with gastroesophageal reflux disease and obstructive lung disease.
Topics: Administration, Inhalation; Administration, Oral; Adult; Aged; Albuterol; Delayed-Action Preparation | 1992 |
[Plasma concentrations of theophylline in patients with chronic obstructive pulmonary disease. What therapeutic limit should be used?].
Topics: Humans; Lung Diseases, Obstructive; Theophylline | 1992 |
Comparative investigation of the influence of nizatidine, ranitidine, and cimetidine on the steady-state pharmacokinetics of theophylline in COPD patients.
Topics: Administration, Oral; Aged; Cimetidine; Delayed-Action Preparations; Humans; Lung Diseases, Obstruct | 1992 |
Caffeine concentrations in adult patients chronically taking theophylline.
Topics: Adult; Aged; Caffeine; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Theophylline | 1992 |
Role of theophyllines in severe chronic obstructive pulmonary disease.
Topics: Bronchi; Delayed-Action Preparations; Diaphragm; Humans; Lung; Lung Diseases, Obstructive; Pulmonary | 1991 |
Impact of rokitamycin, a new 16-membered macrolide, on serum theophylline.
Topics: Aged; Aminophylline; Anti-Bacterial Agents; Humans; Lung Diseases, Obstructive; Male; Middle Aged; M | 1991 |
Air-driven nebulised high-dose salbutamol in severe chronic obstructive airways disease: is it safe?
Topics: Aged; Albuterol; Delayed-Action Preparations; Drug Therapy, Combination; Female; Heart Rate; Humans; | 1991 |
Use of troleandomycin as a steroid-sparing agent in both asthma and chronic obstructive pulmonary disease.
Topics: Adrenal Cortex Hormones; Aged; Asthma; Female; Humans; Lung Diseases, Obstructive; Male; Methylpredn | 1991 |
[Euphylong in patients with chronic obstructive airway diseases].
Topics: Adult; Aged; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Middle Aged | 1991 |
When is the use of alternative biological fluid in pharmacokinetics possible; an example of theophylline.
Topics: Adolescent; Adult; Aged; Asthma; Child; Female; Humans; Injections, Intravenous; Lung Diseases, Obst | 1991 |
A prospective evaluation of elevated serum theophylline concentrations to determine if high concentrations are predictable.
Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Body Weight; Humans; Lung Diseases, Obstructiv | 1991 |
Effect of theophylline on urinary excretion of 3-methylhistidine in patients with lung disease.
Topics: Adult; Aged; Asthma; Blood Urea Nitrogen; Creatinine; Female; Humans; Lung Diseases, Obstructive; Ma | 1991 |
Influence of sulbactam plus ampicillin on theophylline clearance.
Topics: Adult; Ampicillin; Drug Interactions; Fluorescence Polarization Immunoassay; Half-Life; Humans; Lung | 1991 |
[Effect of ranitidine on the pharmacokinetics of theophylline in patients with obstructive pulmonary disease].
Topics: Adult; Drug Therapy, Combination; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Ran | 1991 |
[Therapy of obstructive respiratory tract diseases].
Topics: Algorithms; Cromolyn Sodium; Drug Therapy, Combination; Glucocorticoids; Humans; Lung Diseases, Obst | 1991 |
[The evaluation in primary care of blood theophylline in patients with chronic obstructive pulmonary disease].
Topics: Aged; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Primary Health Care; Spain; The | 1991 |
Nonlinear theophylline pharmacokinetics. A preventable cause of iatrogenic theophylline toxic reactions.
Topics: Drug Administration Schedule; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Theophylline | 1991 |
Individualization of theophylline dosage: a Bayesian method evaluated in patients with once-daily dosing.
Topics: Adult; Aged; Bayes Theorem; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug | 1991 |
Theophylline is no more obsolete than "two puffs qid" of current beta 2 agonists.
Topics: Adrenergic beta-Agonists; Anti-Inflammatory Agents; Canada; Humans; Lung Diseases, Obstructive; Nebu | 1990 |
[Treatment of acute crisis of chronic respiratory failure].
Topics: Asthma; Chronic Disease; Histamine H1 Antagonists; Humans; Lung Diseases, Obstructive; Pulmonary Fib | 1990 |
Hypomagnesemia in chronic obstructive lung disease: effect of therapy.
Topics: Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta-Agonists; | 1990 |
Precise diagnosis of airflow obstruction - does it matter for treatment? The assessment of reversibility; what drugs?
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Bronchodilator Agents; Histamine Antagonists; Hum | 1990 |
Therapeutic implications of a precise diagnosis of airflow obstruction.
Topics: Adrenergic beta-Agonists; Asthma; Bronchodilator Agents; Humans; Lung Diseases, Obstructive; Parasym | 1990 |
Theophylline levels in COPD exacerbations.
Topics: Acute Disease; Humans; Lung Diseases, Obstructive; Theophylline | 1991 |
[Therapeutic effectiveness of bamifylline in elderly patients with COPD].
Topics: Aged; Bronchodilator Agents; Dyspnea; Female; Humans; Lung Diseases, Obstructive; Male; Respiratory | 1991 |
Chronotherapy of reversible airways disease with once-daily evening doses of a controlled-release theophylline preparation.
Topics: Asthma; Circadian Rhythm; Delayed-Action Preparations; Humans; Lung Diseases, Obstructive; Theophyll | 1991 |
The arrhythmogenicity of theophylline. A multivariate analysis of clinical determinants.
Topics: Aged; Arrhythmias, Cardiac; Asthma; Cross-Sectional Studies; Electrocardiography; Female; Heart Rate | 1991 |
Inadequate follow-up of abnormal lab values.
Topics: Aged; Centers for Medicare and Medicaid Services, U.S.; Female; Humans; Lung Diseases, Obstructive; | 1991 |
Permanent brain damage possibly caused by theophylline in two elderly patients with airway obstruction.
Topics: Aged; Asthma; Brain Diseases; Female; Humans; Lung Diseases, Obstructive; Male; Seizures; Theophylli | 1990 |
[Chronic theophylline treatment in chronic airflow obstruction. Relations between doses, blood levels and expiratory flow].
Topics: Aged; Humans; Lung Diseases, Obstructive; Male; Peak Expiratory Flow Rate; Theophylline; Time Factor | 1990 |
Hypophosphatemia in course of chronic obstructive pulmonary disease. Prevalence, mechanisms, and relationships with skeletal muscle phosphorus content.
Topics: Adult; Aged; Aged, 80 and over; Carbon Dioxide; Clenbuterol; Female; Furosemide; Humans; Kidney; Lun | 1990 |
Theophylline plasma clearance in critically ill geriatric patients receiving total parenteral nutrition and in control patients.
Topics: Age Factors; Aged; Critical Care; Dose-Response Relationship, Drug; Humans; Infusions, Intravenous; | 1990 |
Aminophylline in the outpatient management of decompensated chronic obstructive pulmonary disease.
Topics: Aged; Ambulatory Care; Aminophylline; Carbon Dioxide; Drug Therapy, Combination; Emergency Service, | 1990 |
[Effects of theophylline on the course of hypercapnic respiratory insufficiency].
Topics: Aged; Drug Evaluation; Humans; Hypercapnia; Lung Diseases, Obstructive; Male; Middle Aged; Respirato | 1990 |
Use of serum theophylline level as a guide to optimum therapy in patients with chronic obstructive lung disease.
Topics: Aged; Cyclic AMP; Delayed-Action Preparations; Female; Forced Expiratory Volume; Humans; Lung Diseas | 1990 |
Pharmacokinetic study of controlled-release choline theophyllinate in elderly patients.
Topics: Aged; Aged, 80 and over; Bronchodilator Agents; Choline; Delayed-Action Preparations; Female; Half-L | 1990 |
A single oral dose method for predicting steady state theophylline concentrations in clinical practice.
Topics: Adult; Aged; Drug Administration Schedule; Female; Humans; Lung Diseases, Obstructive; Male; Middle | 1990 |
Impairment of theophylline clearance by a hypocaloric low-protein diet in chronic obstructive pulmonary disease.
Topics: Aged; Diet, Reducing; Dietary Proteins; Humans; Lung Diseases, Obstructive; Male; Protein Binding; T | 1990 |
Risk of toxicity in patients with elevated theophylline levels.
Topics: Aged; Arrhythmias, Cardiac; Causality; Female; Heart Failure; Humans; Hypotension; Intensive Care Un | 1990 |
[Theophylline toxicity in infants].
Topics: Bronchiolitis; Bronchitis; Child; Child, Preschool; Dose-Response Relationship, Drug; Humans; Infant | 1990 |
[Interactions of theophylline and nifedipine].
Topics: Adult; Delayed-Action Preparations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hy | 1990 |
Pharmacological treatment of respiratory insufficiency.
Topics: Animals; Digitalis; Dogs; Humans; Lung Diseases, Obstructive; Muscle Contraction; Plants, Medicinal; | 1990 |
Is theophylline obsolete?
Topics: Administration, Inhalation; Aerosols; Anti-Inflammatory Agents; Bronchodilator Agents; Humans; Lung | 1990 |
Theophylline therapy. A continuing dilemma.
Topics: Humans; Lung Diseases, Obstructive; Theophylline | 1990 |
Plasma theophylline concentration and lung function in ponies with recurrent obstructive lung disease.
Topics: Airway Resistance; Aminophylline; Animals; Blood Gas Analysis; Drug Interactions; Heart Rate; Horse | 1990 |
Theophylline concentrations in patients with acute exacerbation of COPD.
Topics: Aged; Emergencies; Female; Humans; Lung Diseases, Obstructive; Male; Maximal Expiratory Flow Rate; M | 1990 |
[Dose titration with Euphylong following prior determination of serum concentration in the steady state].
Topics: Adult; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Lung Di | 1990 |
Theophylline toxicity induced by tetracycline.
Topics: Drug Interactions; Female; Humans; Lung Diseases, Obstructive; Middle Aged; Tetracycline; Theophylli | 1990 |
The effect of split virus influenza vaccination on theophylline pharmacokinetics.
Topics: Adolescent; Adult; Aged; Female; Humans; Influenza Vaccines; Influenza, Human; Interferons; Kinetics | 1985 |
Effect of theophylline on respiratory muscle function.
Topics: Aminophylline; Animals; Calcium; Cell Membrane; Diaphragm; Dogs; Humans; In Vitro Techniques; Ion Ch | 1985 |
Response to oral theophylline in severe chronic obstructive airways disease.
Topics: Humans; Lung; Lung Diseases, Obstructive; Theophylline | 1989 |
Theophylline disposition in patients with COLD with and without hypoxemia.
Topics: Biotransformation; Carbon Dioxide; Female; Humans; Hypoxia; Lung Diseases, Obstructive; Male; Middle | 1989 |
[Clinical functional study of a new delayed-action preparation of "once a day" anhydrous theophylline in patients with chronic obstructive bronchopneumopathy].
Topics: Adult; Aged; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obstructive; Male; Middle A | 1989 |
[Staged therapy of chronic obstructive respiratory tract diseases. Treatment of chronic obstructive respiratory tract diseases by the established physician].
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Drug Therapy, Combination; Humans; Lung Diseases, | 1989 |
[Therapeutic drug monitoring of theophylline in the serum and saliva].
Topics: Chromatography, Gas; Chromatography, Liquid; Humans; Lung Diseases, Obstructive; Monitoring, Physiol | 1989 |
Blood oxygen tension-related change of theophylline clearance in experimental hypoxemia.
Topics: Animals; Hypoxia; Lung Diseases, Obstructive; Male; Metabolic Clearance Rate; Oxygen; Partial Pressu | 1989 |
A manifestation of theophylline toxicity.
Topics: Electrocardiography; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Tachycardia, Supraventri | 1989 |
Reversing the irreversible.
Topics: Humans; Lung Diseases, Obstructive; Respiratory Muscles; Theophylline | 1989 |
Theophylline-isoniazid interaction.
Topics: Adult; Drug Interactions; Female; Humans; Isoniazid; Lung Diseases, Obstructive; Metabolic Clearance | 1989 |
Mexiletine-theophylline interaction.
Topics: Aged; Amiodarone; Cardiovascular Diseases; Dose-Response Relationship, Drug; Drug Interactions; Drug | 1989 |
Comparative dose study of a theophylline sustained-release tablet formulation after repeated administrations.
Topics: Aged; Delayed-Action Preparations; Humans; Lung Diseases, Obstructive; Male; Theophylline | 1989 |
[Levels of blood theophylline in patients with acute bronchospasm].
Topics: Acute Disease; Aged; Asthma; Bronchial Spasm; Delayed-Action Preparations; Female; Humans; Lung Dise | 1989 |
Fatal theophylline toxicity precipitated by in situ pulmonary artery thrombosis.
Topics: Half-Life; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Pulmonary Embolism; Pulmonary Hear | 1989 |
Multifocal atrial tachycardia: a toxic effect of theophylline.
Topics: Aged; Aminophylline; Blood Gas Analysis; Digoxin; Female; Heart Atria; Heart Rate; Humans; Lung Dise | 1985 |
Patterns of drug taking in patients with chronic airflow obstruction.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Asthma; Bronchitis; Female; Humans; L | 1985 |
Pharmacologic approaches to obstructive airway disease.
Topics: Acute Disease; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Asthma; Autonomic Nervous S | 1985 |
Chronic obstructive lung disease and acute respiratory failure.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Aerosols; Bronchodilator Agents; Humans; Intubati | 1986 |
Treatment of pulmonary hypertension.
Topics: Adrenergic beta-Agonists; Antihypertensive Agents; Combined Modality Therapy; Humans; Hypertension, | 1986 |
COPD: causes, treatment, and risk for lung cancer.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Bacterial Agents; Combined Modality Therapy; | 1986 |
Effect of famotidine on theophylline clearance in asthma and COPD patients.
Topics: Adult; Aged; Asthma; Famotidine; Female; Histamine H2 Antagonists; Humans; Lung Diseases, Obstructiv | 1987 |
[Recommendations for a stepwise plan of long-term drug therapy in obstructive airway diseases].
Topics: Adrenergic beta-Agonists; Adult; Anti-Bacterial Agents; Asthma; Bronchitis; Child; Expectorants; Glu | 1988 |
Controversies in pulmonary medicine. Patients with COPD should be started initially on anticholinergic bronchodilators.
Topics: Adrenergic beta-Agonists; Bronchodilator Agents; Humans; Lung Diseases, Obstructive; Parasympatholyt | 1988 |
Deposition of aerosols and bronchial clearance measurements.
Topics: Aerosols; Bronchi; Ciliary Motility Disorders; Expectorants; Humans; Ipratropium; Lung Diseases, Obs | 1987 |
[Current broncholytic and expectorant therapy of patients with chronic nonspecific lung diseases].
Topics: Aerosols; Bronchodilator Agents; Drug Combinations; Expectorants; Fenoterol; Humans; Ipratropium; Lu | 1987 |
[The grade of dyspnea in patients treated with a theophylline derivative (bamifylline) vs controlled-absorption theophylline].
Topics: Bronchodilator Agents; Dyspnea; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Physi | 1987 |
[Bronchodilator effectiveness of theophylline].
Topics: Adult; Aged; Airway Resistance; Drug Therapy, Combination; Female; Fenoterol; Humans; Ipratropium; L | 1988 |
[Theophylline in asthma therapy].
Topics: Asthma; Humans; Long-Term Care; Lung Diseases, Obstructive; Theophylline | 1986 |
Supraventricular tachycardia in chronic pulmonary disease.
Topics: Aged; Drug Interactions; Electrocardiography; Erythromycin; Humans; Lung Diseases, Obstructive; Male | 1986 |
[Clinical significance of the pharmacokinetic determination of theophylline].
Topics: Adult; Aged; Aminophylline; Female; Humans; Kinetics; Lung Diseases, Obstructive; Male; Middle Aged; | 1986 |
[Pharmacokinetics and pharmacodynamics of theophylline in geriatric patients with multiple diseases].
Topics: Age Factors; Aged; Carbon Dioxide; Diabetes Complications; Diabetes Mellitus; Female; Half-Life; Hea | 1987 |
[Serum theophylline levels in chronic obstructive pulmonary disease patients receiving uniphyllin].
Topics: Aged; Delayed-Action Preparations; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Theophylli | 1988 |
Induction of theophylline toxicity and inhibition of clearance rates by ranitidine.
Topics: Aged; Female; Humans; Lung Diseases, Obstructive; Male; Metabolic Clearance Rate; Peptic Ulcer; Rani | 1988 |
Rifampicin-isoniazid and delayed elimination of theophylline: a case report.
Topics: Delayed-Action Preparations; Drug Interactions; Drug Therapy, Combination; Humans; Isoniazid; Lung D | 1988 |
[Heart therapy in patients with lung diseases].
Topics: Combined Modality Therapy; Humans; Lung Diseases, Obstructive; Oxygen Inhalation Therapy; Pulmonary | 1988 |
[Compliance improving measures in the treatment of obstructive lung diseases].
Topics: Adult; Child; Humans; Lung Diseases, Obstructive; Patient Compliance; Sick Role; Theophylline | 1988 |
[Controlled treatment with a retard theophylline preparation].
Topics: Airway Resistance; Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Lung Disea | 1988 |
Controversies in pulmonary medicine. Aminophylline should be administered for all acute exacerbations of COPD.
Topics: Aminophylline; Humans; Lung Diseases, Obstructive; Theophylline | 1988 |
[Salivary theophylline concentration as an indirect parameter to monitor plasma theophylline levels].
Topics: Humans; Lung Diseases, Obstructive; Saliva; Theophylline | 1988 |
TDM of theophylline--compliance evaluation.
Topics: Adolescent; Adult; Aged; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Patient Comp | 1988 |
Enoxacin in the treatment of lower respiratory tract infections.
Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Bronchiectasis; Bronchitis; Chronic Disease; Drug | 1988 |
Miocamycin doesn't affect theophylline serum levels in COPD patients.
Topics: Adult; Humans; Leucomycins; Lung Diseases, Obstructive; Male; Miocamycin; Theophylline; Time Factors | 1988 |
Variability in theophylline volume of distribution and clearance in patients with acute respiratory failure requiring mechanical ventilation.
Topics: Acute Disease; Adult; Female; Half-Life; Humans; Lung Diseases, Obstructive; Male; Respiration, Arti | 1988 |
Outpatient management of COPD.
Topics: Adrenal Cortex Hormones; Environment; Humans; Lung Diseases, Obstructive; Oxygen Inhalation Therapy; | 1988 |
Compatibility of premixed theophylline and verapamil intravenous admixtures.
Topics: Chromatography, High Pressure Liquid; Drug Combinations; Drug Incompatibility; Drug Stability; Human | 1988 |
Agreement among physician assessment methods. Searching for the truth among fallible methods.
Topics: Adrenal Cortex Hormones; Adult; Aged; California; Female; Humans; Interviews as Topic; Lung Diseases | 1988 |
Intersubject variability in plasma theophylline levels after oral and intravenous administration in Jordanian patients with chronic obstructive pulmonary disease.
Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Infant; Infa | 1988 |
Pharmacokinetics of theophylline in hyperthyroid and hypothyroid patients with chronic obstructive pulmonary disease.
Topics: Adult; Aged; Female; Humans; Hyperthyroidism; Hypothyroidism; Lung Diseases, Obstructive; Male; Midd | 1987 |
Does aminophylline improve nocturnal hypoxia in patients with chronic airflow obstruction?
Topics: Aged; Aminophylline; Humans; Hypoxia; Infusions, Intravenous; Lung Diseases, Obstructive; Male; Midd | 1987 |
A comparison of absorption rate models in the prediction of steady-state plasma concentrations during oral theophylline administration.
Topics: Administration, Oral; Adult; Aged; Aminophylline; Female; Humans; Infusions, Intravenous; Lung Disea | 1987 |
Does theophylline improve dyspnea in nonreversible COPD?
Topics: Adult; Aged; Dyspnea; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Theophylline | 1986 |
[Enoxacin and theophylline].
Topics: Drug Interactions; Enoxacin; Humans; Lung Diseases, Obstructive; Naphthyridines; Theophylline | 1986 |
The influence of the 4-quinolones ciprofloxacin, pefloxacin and ofloxacin on the elimination of theophylline.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Lung Diseases, Obstructive; Male; Metabo | 1987 |
Prolonged runs of ventricular tachycardia as a complication of theophylline intoxication. Report of a case.
Topics: Aged; Electrocardiography; Heart Ventricles; Humans; Hypokalemia; Lung Diseases, Obstructive; Male; | 1986 |
Combined administration of controlled release theophylline and ranitidine: a 53-day controlled survey in patients with chronic obstructive lung disease (COLD) and peptic disease.
Topics: Aged; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Lung Diseases, Obstruc | 1987 |
Prognosis in chronic obstructive pulmonary disease.
Topics: Adult; Age Factors; Aged; Female; Forced Expiratory Volume; Functional Residual Capacity; Humans; In | 1986 |
Recommended standard theophylline doses are inadequate in chronic obstructive pulmonary disease.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Humans; Lung Diseases, Obstructive; Middle Aged; Theo | 1987 |
[Clinical significance of determining theophylline concentration in serum].
Topics: Administration, Oral; Dose-Response Relationship, Drug; Humans; Kinetics; Lung Diseases, Obstructive | 1986 |
The influence of quinolone derivatives on theophylline clearance.
Topics: Aged; Anti-Infective Agents; Drug Interactions; Female; Humans; Lung Diseases, Obstructive; Male; Me | 1986 |
[Absorption of theophylline from Bronchoparat in relation to preceding food intake].
Topics: Administration, Oral; Adult; Delayed-Action Preparations; Eating; Female; Humans; Intestinal Absorpt | 1987 |
Bronchodilators in chronic air-flow limitation. Effects on airway function, exercise capacity, and quality of life.
Topics: Aged; Albuterol; Bronchodilator Agents; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Nebul | 1987 |
Effect of combined use of intravenous salbutamol and aminophylline on cardiac rhythm in chronic obstructive lung disease.
Topics: Aged; Albuterol; Aminophylline; Drug Therapy, Combination; Female; Heart Rate; Humans; Infusions, In | 1987 |
[Therapeutic non-compliance in patients with chronic airway obstruction].
Topics: Adult; Aged; Aminophylline; Asthma; Female; Humans; Lung Diseases, Obstructive; Male; Medication Err | 1987 |
Using a hand-held spirometer as a monitoring tool in chronic theophylline therapy.
Topics: Adult; Asthma; Child; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Mi | 1987 |
[Theophylline overdoses on admission to a resuscitation unit].
Topics: Acute Disease; Aged; Asthma; Emergency Service, Hospital; Female; Humans; Lung Diseases, Obstructive | 1987 |
Effect of prednisolone on theophylline pharmacokinetics in patients with chronic airflow obstruction.
Topics: Aged; Aminophylline; Drug Interactions; Female; Half-Life; Humans; Kinetics; Lung Diseases, Obstruct | 1987 |
[Convulsions induced by theophylline in adults. Presentation of 4 cases].
Topics: Aged; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Seizures; Theophylline | 1987 |
Post-mortem concentrations of salbutamol, terbutaline and theophylline in asthma patients.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Albuterol; Animals; Asthma; Female; Human | 1987 |
[Clinico-pharmacologic possibilities of theophylline therapy].
Topics: Adolescent; Adult; Child; Child, Preschool; Humans; Infant; Lung Diseases, Obstructive; Theophylline | 1987 |
[Norfloxacin does not raise theophylline concentrations in plasma].
Topics: Aged; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lung Diseases, Obstructive; Male | 1987 |
[Determination of theophylline in the plasma by rapid solid-phase extraction].
Topics: Chromatography, High Pressure Liquid; Humans; Lung Diseases, Obstructive; Theophylline; Uric Acid; X | 1987 |
Evaluation of the effectiveness and safety of a controlled-release theophylline in patients with reversible and stable bronchial obstruction.
Topics: Adult; Asthma; Delayed-Action Preparations; Female; Humans; Lung; Lung Diseases, Obstructive; Male; | 1987 |
Serum theophylline concentrations and pulmonary function tests after administration of two sustained-release formulations containing theophylline in patients affected by chronic obstructive lung disease.
Topics: Aged; Delayed-Action Preparations; Female; Humans; Lung; Lung Diseases, Obstructive; Lung Volume Mea | 1987 |
Oral mexiletine-theophylline interaction.
Topics: Administration, Oral; Aged; Coronary Disease; Drug Interactions; Humans; Lung Diseases, Obstructive; | 1987 |
Audit of serum theophylline concentrations in patients from general practice.
Topics: Adolescent; Adult; Aged; Family Practice; Humans; Lung Diseases, Obstructive; Medical Audit; Middle | 1987 |
Accidental coadministration of intravenous aminophylline and theophylline by mouth: a hazardous practice.
Topics: Accidents; Administration, Oral; Aged; Aminophylline; Humans; Infusions, Parenteral; Lung Diseases, | 1986 |
Sexual problems in chronic respiratory disease. Achieving and maintaining intimacy.
Topics: Aged; Depression; Female; Humans; Lung Diseases, Obstructive; Male; Sexual Dysfunction, Physiologica | 1986 |
Bronchodilator response in chronic obstructive pulmonary disease.
Topics: Adult; Aged; Airway Resistance; Female; Forced Expiratory Volume; Humans; Isoproterenol; Lung Diseas | 1986 |
Circadian changes in the absorption and elimination of theophylline in patients with bronchial obstruction.
Topics: Absorption; Aged; Aminophylline; Asthma; Circadian Rhythm; Delayed-Action Preparations; Female; Huma | 1986 |
Theophylline intoxication following viloxazine induced decrease in clearance.
Topics: Aged; Chronic Disease; Depression, Chemical; Drug Interactions; Female; Humans; Kinetics; Lung Disea | 1986 |
[Individual theophylline doses following ambulatory determination of theophylline clearance].
Topics: Adult; Aged; Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Lung Diseases, O | 1986 |
Theophylline once-a-day dosage.
Topics: Adult; Aged; Drug Administration Schedule; Female; Humans; Lung Diseases, Obstructive; Male; Middle | 1986 |
Evaluation of tetracycline on theophylline disposition in patients with chronic obstructive airways disease.
Topics: Adult; Aged; Drug Interactions; Humans; Kinetics; Lung Diseases, Obstructive; Male; Middle Aged; Tet | 1986 |
Theophylline binding to plasma proteins in patients with chronic obstructive pulmonary disease.
Topics: Adult; Blood Proteins; Humans; Hydrogen-Ion Concentration; Lung Diseases, Obstructive; Protein Bindi | 1986 |
[Bronchodilators: theophylline derivatives].
Topics: Bronchodilator Agents; Humans; Lung Diseases, Obstructive; Theophylline | 1986 |
The disposition of theophylline in blood in chronic obstructive lung disease.
Topics: Adolescent; Adult; Aged; Female; Humans; Kinetics; Lung Diseases, Obstructive; Male; Middle Aged; Th | 1986 |
Enoxacin decreases the clearance of theophylline in man.
Topics: Adult; Aged; Depression, Chemical; Enoxacin; Female; Humans; Lung Diseases, Obstructive; Male; Middl | 1985 |
Effect of empiric dosing on blood levels of theophylline and phenytoin.
Topics: Critical Care; Drug Administration Schedule; Humans; Immunoenzyme Techniques; Lung Diseases, Obstruc | 1985 |
Plasma theophylline concentrations, six minute walking distances, and breathlessness in patients with chronic airflow obstruction.
Topics: Humans; Lung Diseases, Obstructive; Physical Exertion; Theophylline | 1985 |
Theophylline kinetics in chronic obstructive airway disease in the elderly.
Topics: Aged; Aging; Analysis of Variance; Carbon Dioxide; Half-Life; Humans; Hydrogen-Ion Concentration; In | 1985 |
COPD. Assessing functional status.
Topics: Anti-Bacterial Agents; Asthma; Bronchitis; Bronchodilator Agents; Emphysema; Heart Diseases; Hospita | 1985 |
Daily maintenance dose of a long-acting theophylline from a single theophylline serum level.
Topics: Aged; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Theophylline | 1986 |
Rapid assay of serum theophylline levels.
Topics: Adult; Humans; Immunoassay; Lung Diseases, Obstructive; Prospective Studies; Theophylline; Time Fact | 1986 |
Rapid estimation of total body clearance of theophylline in patients receiving intravenous aminophylline infusion.
Topics: Adult; Aged; Aminophylline; Dose-Response Relationship, Drug; Female; Humans; Infusions, Parenteral; | 1986 |
The pendulum swings again. Toward a rational use of theophylline.
Topics: Humans; Lung Diseases, Obstructive; Theophylline | 1985 |
The use of parenteral aminophylline in patients taking slow release theophylline preparations: an observation of clinical practice.
Topics: Adolescent; Adult; Aged; Aminophylline; Delayed-Action Preparations; Drug Administration Schedule; D | 1985 |
[Determination of serum theophylline concentration in ambulatory practice].
Topics: Aged; Ambulatory Care; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obstructive; Male | 1985 |
Protein binding of theophylline.
Topics: Aged; Female; Humans; Lung Diseases, Obstructive; Protein Binding; Theophylline | 1985 |
Alterations in theophylline protein binding in acutely ill patients with COPD.
Topics: Acute Disease; Adult; Aged; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Lung Diseases, Obs | 1985 |
Effect of rifampicin administration on theophylline pharmacokinetics in humans.
Topics: Adult; Asthma; Drug Interactions; Humans; Kinetics; Lung Diseases, Obstructive; Male; Rifampin; Theo | 1985 |
Managing asthma and COPD in patients with cardiovascular disease.
Topics: Adult; Aged; Arrhythmias, Cardiac; Asthma; Cardiovascular Diseases; Digitalis; Digitalis Glycosides; | 1985 |
[Results of a serum concentration-oriented dosage of a theophylline depot preparation in ambulatory patients with chronic obstructive lung disease].
Topics: Adult; Aged; Delayed-Action Preparations; Female; Humans; Lung Diseases, Obstructive; Male; Middle A | 1985 |
Theophylline serum concentrations in ambulatory patients with chronic obstructive pulmonary disease.
Topics: Aged; Ambulatory Care; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Theophylline | 1985 |
Theophylline: a diagnostic aid for evaluating chronic airways obstruction.
Topics: Humans; Injections, Intravenous; Lung Diseases, Obstructive; Male; Middle Aged; Pulmonary Alveoli; P | 1985 |
Serum theophylline--a mandatory measurement in the control of therapy?
Topics: Adolescent; Adult; Asthma; Delayed-Action Preparations; Female; Humans; Kinetics; Lung Diseases, Obs | 1985 |
[Minimal blood levels of theophylline: circadian rhythm].
Topics: Aged; Asthma; Circadian Rhythm; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Theop | 1985 |
[Clinico-pharmacologic aspects of prescribing theophylline-containing preparations].
Topics: Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Lung Diseases, Obstructive; T | 1985 |
Relationship between saliva and free and total plasma theophylline concentrations in patients with chronic airflow obstruction.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Female; Humans; Lung Diseases, Obstructive; Male; | 1985 |
Increased activity of creatine kinase isoenzyme MB in a theophylline-intoxicated patient.
Topics: Aged; Aspartate Aminotransferases; Creatine Kinase; Diagnosis, Differential; Female; Humans; Isoenzy | 1985 |
Responses to large doses of salbutamol and theophylline in patients with chronic obstructive pulmonary disease.
Topics: Aged; Airway Resistance; Albuterol; Drug Therapy, Combination; Female; Forced Expiratory Volume; Hum | 1985 |
Early use of oral theophylline in hospitalized chronic obstructive pulmonary disease patients: cost-containment through medical education.
Topics: Administration, Oral; Cost Control; Drug Utilization; Humans; Infusions, Parenteral; Internship and | 1985 |
Atrial arrhythmias exacerbated by theophylline. Response to verapamil and evidence for triggered activity in man.
Topics: Aged; Digoxin; Electrocardiography; Female; Heart Atria; Humans; Lung Diseases, Obstructive; Recurre | 1985 |
Therapeutic activity of ambroxol theophyllinacetate in chronic obstructive pulmonary diseases.
Topics: Aged; Ambroxol; Bromhexine; Drug Evaluation; Female; Humans; Lung Diseases, Obstructive; Male; Theop | 1985 |
Methylxanthine therapy and reversible airway obstruction.
Topics: Adult; Age Factors; Asthma; Child; Delayed-Action Preparations; Diet; Drug Interactions; Half-Life; | 1985 |
[Treatment and surveillance of severe chronic respiratory insufficiency].
Topics: Anti-Bacterial Agents; Breathing Exercises; Bronchodilator Agents; Caffeine; Chronic Disease; Expect | 1973 |
[New drug composition, used as a room aerosol].
Topics: Aerosols; Ascorbic Acid; Boric Acids; Drug Combinations; Humans; Isoproterenol; Lung Diseases, Obstr | 1972 |
Theophylline toxicity due to impaired theophylline degradation.
Topics: Administration, Oral; Aged; Electrocardiography; Humans; Lung Diseases, Obstructive; Male; Oxygen In | 1974 |
[Therapeutical effect of a new antidyspnoeic drug in the chronic obstructive pulmonary disease (author's transl)].
Topics: Adult; Aged; Anti-Inflammatory Agents; Bronchitis; Bronchodilator Agents; Chronic Disease; Diphenhyd | 1973 |
Special problems in respiratory diseases.
Topics: Adrenal Cortex Hormones; Aged; Aging; Anti-Bacterial Agents; Anticoagulants; Asthma; Bronchodilator | 1974 |
[Therapy of chronic-obstructive ailments of the respiratory tract].
Topics: Bronchitis; Chronic Disease; Humans; Injections, Intravenous; Khellin; Lung Diseases; Lung Diseases, | 1970 |