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theophylline and Nervous System Disorders

theophylline has been researched along with Nervous System Disorders in 19 studies

Research Excerpts

ExcerptRelevanceReference
"We presume it necessary to pay heed to fever and neurologic predispositions in order to prevent sequelae or death that may occur subsequently to seizures that developed during theophylline administration."7.74[Clinical review of patients with seizures that developed during theophylline administration--(III) Safety of theophylline examined in patients who had sequelae or died]. ( Kato, T; Nakano, H; Odajima, Y; Okada, K, 2008)
"Theophylline is a useful drug for the treatment of asthma."7.73A prospective survey on safety of sustained-release theophylline in treatment of asthma and COPD. ( Adachi, M; Fukuda, T; Kihara, N; Makino, S; Miyamoto, T; Nakajima, S; Nishima, S; Ohta, K, 2006)
"We report 12 adults with seizures associated with serum theophylline levels between 14 and 35 mg/l."7.68Theophylline-associated seizures with "therapeutic" or low toxic serum concentrations: risk factors for serious outcome in adults. ( Bahls, FH; Bird, TD; Ma, KK, 1991)
"We presume it necessary to pay heed to fever and neurologic predispositions in order to prevent sequelae or death that may occur subsequently to seizures that developed during theophylline administration."3.74[Clinical review of patients with seizures that developed during theophylline administration--(III) Safety of theophylline examined in patients who had sequelae or died]. ( Kato, T; Nakano, H; Odajima, Y; Okada, K, 2008)
"Theophylline is a useful drug for the treatment of asthma."3.73A prospective survey on safety of sustained-release theophylline in treatment of asthma and COPD. ( Adachi, M; Fukuda, T; Kihara, N; Makino, S; Miyamoto, T; Nakajima, S; Nishima, S; Ohta, K, 2006)
"The purpose of the present investigation was to evaluate whether antiinflammatory drugs affect the pharmacodynamics of theophylline-induced seizures."3.69Differential effects of various antiinflammatory drugs on theophylline neurotoxicity. ( Afargan, M; Backon, J; Gilhar, D; Hoffman, A; Pinto, E, 1994)
" In particular, theophylline-induced seizures, which are often fatal and occur unpredictably over a wide range of serum theophylline concentrations, may be precipitated."3.69Cyclosporine enhances theophylline neurotoxicity in rats. ( Afargan, M; Hoffman, A; Pinto, E; Schattner, A, 1994)
"We report 12 adults with seizures associated with serum theophylline levels between 14 and 35 mg/l."3.68Theophylline-associated seizures with "therapeutic" or low toxic serum concentrations: risk factors for serious outcome in adults. ( Bahls, FH; Bird, TD; Ma, KK, 1991)
"Theophylline can cause life-threatening seizures when administered in excessive doses."3.67Caffeine as a potential risk factor for theophylline neurotoxicity. ( Levy, G; Yasuhara, M, 1988)
"Aminophylline therapy has undergone change in the past decade."2.37Aminophylline toxicity. ( Albert, S, 1987)
" Theophylline, a re-emerging drug for the treatment of obstructive airway disease, has a narrow therapeutic index which precludes its safe use."1.34Free radicals and theophylline neurotoxicity : an experimental study. ( Gulati, K; Ray, A; Vijayan, VK, 2007)
"Glycerol acute renal failure (ARF) was examined to see if it alters theophylline (Th) neurotoxicity in rats."1.28Theophylline neurotoxicity is unaffected by glycerol-induced renal failure. ( Ramzan, I, 1990)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19908 (42.11)18.7374
1990's8 (42.11)18.2507
2000's3 (15.79)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Odajima, Y1
Nakano, H1
Kato, T1
Okada, K1
BRANDT, H1
Makino, S1
Adachi, M1
Ohta, K1
Kihara, N1
Nakajima, S1
Nishima, S1
Fukuda, T1
Miyamoto, T1
Gulati, K1
Ray, A1
Vijayan, VK1
Hoffman, A4
Afargan, M2
Pinto, E2
Gilhar, D1
Backon, J1
Schattner, A1
MacGregor, DG1
Stone, TW1
Tominaga, K1
Shibata, S1
Watanabe, S1
Bahls, FH1
Ma, KK1
Bird, TD1
Ramzan, I1
Levy, G5
Sato, S1
Yasuhara, M3
Albert, S1
Astbury, J1
Orgill, AA1
Bajuk, B1
Yu, VY1
Woody, RC1
Laney, M1

Reviews

1 review available for theophylline and Nervous System Disorders

ArticleYear
Aminophylline toxicity.
    Pediatric clinics of North America, 1987, Volume: 34, Issue:1

    Topics: Adolescent; Aminophylline; Cardiovascular Diseases; Child; Gastrointestinal Diseases; Humans; Kineti

1987

Other Studies

18 other studies available for theophylline and Nervous System Disorders

ArticleYear
[Clinical review of patients with seizures that developed during theophylline administration--(III) Safety of theophylline examined in patients who had sequelae or died].
    Arerugi = [Allergy], 2008, Volume: 57, Issue:5

    Topics: Age Factors; Child; Child, Preschool; Communicable Diseases; Drug-Related Side Effects and Adverse R

2008
[Contribution to local anesthesia and neural therapy].
    Medizinische Monatsschrift, 1956, Volume: 10, Issue:6

    Topics: Coal Tar; Disease; Focal Infection; Nervous System Diseases; Procaine; Spinal Diseases; Spine; Theop

1956
A prospective survey on safety of sustained-release theophylline in treatment of asthma and COPD.
    Allergology international : official journal of the Japanese Society of Allergology, 2006, Volume: 55, Issue:4

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Anti-Asthmatic Agents; Asthma; Bronchiti

2006
Free radicals and theophylline neurotoxicity : an experimental study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2007, May-30, Volume: 53, Issue:5

    Topics: alpha-Tocopherol; Aminophylline; Animals; Antioxidants; Arginine; Ascorbic Acid; Dose-Response Relat

2007
Differential effects of various antiinflammatory drugs on theophylline neurotoxicity.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal;

1994
Cyclosporine enhances theophylline neurotoxicity in rats.
    Journal of pharmaceutical sciences, 1994, Volume: 83, Issue:4

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Proteins; Blood Urea Nitrogen; Chr

1994
Inhibition by the adenosine analogue, (R-)-N6-phenylisopropyladenosine, of kainic acid neurotoxicity in rat hippocampus after systemic administration.
    British journal of pharmacology, 1993, Volume: 109, Issue:2

    Topics: Animals; Behavior, Animal; Body Temperature; Hippocampus; Isoquinolines; Kainic Acid; Kinetics; Male

1993
Potential pharmacodynamic effect of charcoal on theophylline neurotoxicity in normal rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:2

    Topics: Animals; Brain; Charcoal; Male; Nervous System Diseases; Rats; Seizures; Theophylline

1992
A neuroprotective effect of adenosine A1-receptor agonists on ischemia-induced decrease in 2-deoxyglucose uptake in rat hippocampal slices.
    Neuroscience letters, 1992, Sep-28, Volume: 145, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain Ischemia; Deoxyglucose; Hippocampus; In

1992
Theophylline-associated seizures with "therapeutic" or low toxic serum concentrations: risk factors for serious outcome in adults.
    Neurology, 1991, Volume: 41, Issue:8

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Epilepsy; Female; Humans; Male; Middle Aged; Nervous Syste

1991
Theophylline neurotoxicity is unaffected by glycerol-induced renal failure.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:3

    Topics: Acute Kidney Injury; Animals; Glycerol; Male; Nervous System Diseases; Rats; Rats, Inbred Strains; S

1990
Kinetics of drug action in disease states. XXXIX. Effect of orally administered activated charcoal on the hypnotic activity of phenobarbital and the neurotoxicity of theophylline administered intravenously to rats with renal failure.
    Pharmaceutical research, 1990, Volume: 7, Issue:3

    Topics: Animals; Blood Proteins; Charcoal; Hypnotics and Sedatives; Injections, Intravenous; Kidney Failure,

1990
Systemic effect of ipecac on acute toxicity of phenobarbital and theophylline in rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1989, Volume: 13, Issue:3

    Topics: Animals; Cardiovascular Diseases; Ipecac; Male; Nervous System Diseases; Phenobarbital; Rats; Rats,

1989
Effect of age on neurotoxicity of theophylline.
    Journal of pharmaceutical sciences, 1988, Volume: 77, Issue:7

    Topics: Aging; Animals; Male; Nervous System Diseases; Rats; Rats, Inbred F344; Theophylline

1988
Kinetics of drug action in disease states XXVIII: Effect of acute hypovolemia on theophylline-induced neurotoxicity in rats.
    Journal of pharmaceutical sciences, 1988, Volume: 77, Issue:8

    Topics: Animals; Male; Nervous System Diseases; Rats; Rats, Inbred Strains; Seizures; Shock; Theophylline

1988
Caffeine as a potential risk factor for theophylline neurotoxicity.
    Journal of pharmaceutical sciences, 1988, Volume: 77, Issue:9

    Topics: Animals; Blood Proteins; Brain; Caffeine; Dialysis; Injections, Intravenous; Male; Nervous System Di

1988
Neonatal and neurodevelopmental significance of behaviour in very low birthweight children.
    Early human development, 1985, Volume: 11, Issue:2

    Topics: Attention; Birth Weight; Child Behavior Disorders; Child, Preschool; Humans; Infant, Low Birth Weigh

1985
A second case of infantile intracranial hemorrhage and severe neurological sequelae following theophylline overdose.
    Developmental medicine and child neurology, 1986, Volume: 28, Issue:1

    Topics: Cerebral Hemorrhage; Humans; Infant; Medication Errors; Nervous System Diseases; Theophylline

1986