theophylline has been researched along with Nervous System Disorders in 19 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We presume it necessary to pay heed to fever and neurologic predispositions in order to prevent sequelae or death that may occur subsequently to seizures that developed during theophylline administration." | 7.74 | [Clinical review of patients with seizures that developed during theophylline administration--(III) Safety of theophylline examined in patients who had sequelae or died]. ( Kato, T; Nakano, H; Odajima, Y; Okada, K, 2008) |
| "Theophylline is a useful drug for the treatment of asthma." | 7.73 | A prospective survey on safety of sustained-release theophylline in treatment of asthma and COPD. ( Adachi, M; Fukuda, T; Kihara, N; Makino, S; Miyamoto, T; Nakajima, S; Nishima, S; Ohta, K, 2006) |
| "We report 12 adults with seizures associated with serum theophylline levels between 14 and 35 mg/l." | 7.68 | Theophylline-associated seizures with "therapeutic" or low toxic serum concentrations: risk factors for serious outcome in adults. ( Bahls, FH; Bird, TD; Ma, KK, 1991) |
| "We presume it necessary to pay heed to fever and neurologic predispositions in order to prevent sequelae or death that may occur subsequently to seizures that developed during theophylline administration." | 3.74 | [Clinical review of patients with seizures that developed during theophylline administration--(III) Safety of theophylline examined in patients who had sequelae or died]. ( Kato, T; Nakano, H; Odajima, Y; Okada, K, 2008) |
| "Theophylline is a useful drug for the treatment of asthma." | 3.73 | A prospective survey on safety of sustained-release theophylline in treatment of asthma and COPD. ( Adachi, M; Fukuda, T; Kihara, N; Makino, S; Miyamoto, T; Nakajima, S; Nishima, S; Ohta, K, 2006) |
| "The purpose of the present investigation was to evaluate whether antiinflammatory drugs affect the pharmacodynamics of theophylline-induced seizures." | 3.69 | Differential effects of various antiinflammatory drugs on theophylline neurotoxicity. ( Afargan, M; Backon, J; Gilhar, D; Hoffman, A; Pinto, E, 1994) |
| " In particular, theophylline-induced seizures, which are often fatal and occur unpredictably over a wide range of serum theophylline concentrations, may be precipitated." | 3.69 | Cyclosporine enhances theophylline neurotoxicity in rats. ( Afargan, M; Hoffman, A; Pinto, E; Schattner, A, 1994) |
| "We report 12 adults with seizures associated with serum theophylline levels between 14 and 35 mg/l." | 3.68 | Theophylline-associated seizures with "therapeutic" or low toxic serum concentrations: risk factors for serious outcome in adults. ( Bahls, FH; Bird, TD; Ma, KK, 1991) |
| "Theophylline can cause life-threatening seizures when administered in excessive doses." | 3.67 | Caffeine as a potential risk factor for theophylline neurotoxicity. ( Levy, G; Yasuhara, M, 1988) |
| "Aminophylline therapy has undergone change in the past decade." | 2.37 | Aminophylline toxicity. ( Albert, S, 1987) |
| " Theophylline, a re-emerging drug for the treatment of obstructive airway disease, has a narrow therapeutic index which precludes its safe use." | 1.34 | Free radicals and theophylline neurotoxicity : an experimental study. ( Gulati, K; Ray, A; Vijayan, VK, 2007) |
| "Glycerol acute renal failure (ARF) was examined to see if it alters theophylline (Th) neurotoxicity in rats." | 1.28 | Theophylline neurotoxicity is unaffected by glycerol-induced renal failure. ( Ramzan, I, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (42.11) | 18.7374 |
| 1990's | 8 (42.11) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Odajima, Y | 1 |
| Nakano, H | 1 |
| Kato, T | 1 |
| Okada, K | 1 |
| BRANDT, H | 1 |
| Makino, S | 1 |
| Adachi, M | 1 |
| Ohta, K | 1 |
| Kihara, N | 1 |
| Nakajima, S | 1 |
| Nishima, S | 1 |
| Fukuda, T | 1 |
| Miyamoto, T | 1 |
| Gulati, K | 1 |
| Ray, A | 1 |
| Vijayan, VK | 1 |
| Hoffman, A | 4 |
| Afargan, M | 2 |
| Pinto, E | 2 |
| Gilhar, D | 1 |
| Backon, J | 1 |
| Schattner, A | 1 |
| MacGregor, DG | 1 |
| Stone, TW | 1 |
| Tominaga, K | 1 |
| Shibata, S | 1 |
| Watanabe, S | 1 |
| Bahls, FH | 1 |
| Ma, KK | 1 |
| Bird, TD | 1 |
| Ramzan, I | 1 |
| Levy, G | 5 |
| Sato, S | 1 |
| Yasuhara, M | 3 |
| Albert, S | 1 |
| Astbury, J | 1 |
| Orgill, AA | 1 |
| Bajuk, B | 1 |
| Yu, VY | 1 |
| Woody, RC | 1 |
| Laney, M | 1 |
1 review available for theophylline and Nervous System Disorders
| Article | Year |
|---|---|
Aminophylline toxicity.
Topics: Adolescent; Aminophylline; Cardiovascular Diseases; Child; Gastrointestinal Diseases; Humans; Kineti | 1987 |
18 other studies available for theophylline and Nervous System Disorders
| Article | Year |
|---|---|
[Clinical review of patients with seizures that developed during theophylline administration--(III) Safety of theophylline examined in patients who had sequelae or died].
Topics: Age Factors; Child; Child, Preschool; Communicable Diseases; Drug-Related Side Effects and Adverse R | 2008 |
[Contribution to local anesthesia and neural therapy].
Topics: Coal Tar; Disease; Focal Infection; Nervous System Diseases; Procaine; Spinal Diseases; Spine; Theop | 1956 |
A prospective survey on safety of sustained-release theophylline in treatment of asthma and COPD.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Anti-Asthmatic Agents; Asthma; Bronchiti | 2006 |
Free radicals and theophylline neurotoxicity : an experimental study.
Topics: alpha-Tocopherol; Aminophylline; Animals; Antioxidants; Arginine; Ascorbic Acid; Dose-Response Relat | 2007 |
Differential effects of various antiinflammatory drugs on theophylline neurotoxicity.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; | 1994 |
Cyclosporine enhances theophylline neurotoxicity in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Proteins; Blood Urea Nitrogen; Chr | 1994 |
Inhibition by the adenosine analogue, (R-)-N6-phenylisopropyladenosine, of kainic acid neurotoxicity in rat hippocampus after systemic administration.
Topics: Animals; Behavior, Animal; Body Temperature; Hippocampus; Isoquinolines; Kainic Acid; Kinetics; Male | 1993 |
Potential pharmacodynamic effect of charcoal on theophylline neurotoxicity in normal rats.
Topics: Animals; Brain; Charcoal; Male; Nervous System Diseases; Rats; Seizures; Theophylline | 1992 |
A neuroprotective effect of adenosine A1-receptor agonists on ischemia-induced decrease in 2-deoxyglucose uptake in rat hippocampal slices.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain Ischemia; Deoxyglucose; Hippocampus; In | 1992 |
Theophylline-associated seizures with "therapeutic" or low toxic serum concentrations: risk factors for serious outcome in adults.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Epilepsy; Female; Humans; Male; Middle Aged; Nervous Syste | 1991 |
Theophylline neurotoxicity is unaffected by glycerol-induced renal failure.
Topics: Acute Kidney Injury; Animals; Glycerol; Male; Nervous System Diseases; Rats; Rats, Inbred Strains; S | 1990 |
Kinetics of drug action in disease states. XXXIX. Effect of orally administered activated charcoal on the hypnotic activity of phenobarbital and the neurotoxicity of theophylline administered intravenously to rats with renal failure.
Topics: Animals; Blood Proteins; Charcoal; Hypnotics and Sedatives; Injections, Intravenous; Kidney Failure, | 1990 |
Systemic effect of ipecac on acute toxicity of phenobarbital and theophylline in rats.
Topics: Animals; Cardiovascular Diseases; Ipecac; Male; Nervous System Diseases; Phenobarbital; Rats; Rats, | 1989 |
Effect of age on neurotoxicity of theophylline.
Topics: Aging; Animals; Male; Nervous System Diseases; Rats; Rats, Inbred F344; Theophylline | 1988 |
Kinetics of drug action in disease states XXVIII: Effect of acute hypovolemia on theophylline-induced neurotoxicity in rats.
Topics: Animals; Male; Nervous System Diseases; Rats; Rats, Inbred Strains; Seizures; Shock; Theophylline | 1988 |
Caffeine as a potential risk factor for theophylline neurotoxicity.
Topics: Animals; Blood Proteins; Brain; Caffeine; Dialysis; Injections, Intravenous; Male; Nervous System Di | 1988 |
Neonatal and neurodevelopmental significance of behaviour in very low birthweight children.
Topics: Attention; Birth Weight; Child Behavior Disorders; Child, Preschool; Humans; Infant, Low Birth Weigh | 1985 |
A second case of infantile intracranial hemorrhage and severe neurological sequelae following theophylline overdose.
Topics: Cerebral Hemorrhage; Humans; Infant; Medication Errors; Nervous System Diseases; Theophylline | 1986 |