theophylline has been researched along with Neoplasms in 24 studies
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetaldehyde formation was determined by GC-FID analysis in the head space of incubation mixtures." | 5.31 | Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects. ( Castro, GD; Castro, JA; Costantini, MH; Delgado de Layño, AM, 2001) |
| " The aims of the study are early detection of acute kidney injury (AKI) with biomarkers and investigation of the potential nephron-protective effects of theophylline." | 5.22 | The efficacy of theophylline in preventing cisplatin-related nephrotoxicity in patients with cancer. ( Dogruel, F; Karademir, LD; Kocyigit, I; Oymak, O; Sipahioglu, MH; Tokgoz, B; Unal, A; Yazici, C, 2016) |
| " Chemotherapeutic patients who received cisplatin at a dosage of at least 50 mg/m 2 alone or in combination with other chemotherapy agent(s) were included in the study." | 2.79 | The protective effect of theophyline in cisplatin nephrotoxicity. ( Ghorbani, A; Golzari, K; Hayati, F; Khanzadeh, A; Motemednia, F; Mousavi, MB; Mousavi, SS; Shahbazian, H; Valavi, E; Zadeh, MH, 2014) |
| " Patients received cisplatin at a dosage of 50 mg/m(2) either combined with etoposide, ifosfamide, and epirubicin or with paclitaxel and 5-fluorouracil/folinic acid with the usual precautions, including a standard hydration scheme before application of cisplatin in both arms." | 2.71 | Nephroprotection by theophylline in patients with cisplatin chemotherapy: a randomized, single-blinded, placebo-controlled trial. ( Benoehr, P; Bokemeyer, C; Grenz, A; Hartmann, JT; Krueth, P; Osswald, H, 2005) |
| "Acetaldehyde formation was determined by GC-FID analysis in the head space of incubation mixtures." | 1.31 | Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects. ( Castro, GD; Castro, JA; Costantini, MH; Delgado de Layño, AM, 2001) |
| "Theophylline and MELPH were also found to act synergistically on the induction of SCEs." | 1.27 | Synergistic induction of sister-chromatid exchanges in lymphocytes from normal subjects and from patients under cytostatic therapy by inhibitors of poly(ADP-ribose)polymerase and antitumour agents. ( Dozi-Vassiliades, J; Hatzitheodoridou, P; Kourakis, A; Mourelatos, D; Tsiouris, J, 1985) |
| "Theophylline was added to cultures at final concentrations of 1 to 3 mM." | 1.26 | Effects of theophylline on the cell growth of normal and malignant human cells transformed in culture. ( Kimoto, T; Namba, M; Nishitani, K, 1980) |
| "In 26 patients with malignancy and in 10 control subjects the excretion of cyclic guanosine 3',5'-monophosphate (cGMP) was also evaluated." | 1.26 | Urinary excretion of cyclic adenosine 3',5'-monophosphate and cyclic guanosine 3',5'-monophosphate in malignancy. ( Francini, G; Galli, M; Gennari, C; Lore, F, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (41.67) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 5 (20.83) | 29.6817 |
| 2010's | 5 (20.83) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Yao, D | 1 |
| You, J | 1 |
| Yang, X | 1 |
| Zhang, J | 1 |
| Yao, X | 1 |
| Mousavi, SS | 1 |
| Zadeh, MH | 1 |
| Shahbazian, H | 1 |
| Khanzadeh, A | 1 |
| Hayati, F | 1 |
| Ghorbani, A | 1 |
| Golzari, K | 1 |
| Valavi, E | 1 |
| Motemednia, F | 1 |
| Mousavi, MB | 1 |
| Karademir, LD | 1 |
| Dogruel, F | 1 |
| Kocyigit, I | 1 |
| Yazici, C | 1 |
| Unal, A | 1 |
| Sipahioglu, MH | 1 |
| Oymak, O | 1 |
| Tokgoz, B | 1 |
| Franco, R | 1 |
| Osowski, A | 1 |
| Pietrzak, M | 1 |
| Wieczorek, Z | 1 |
| Wieczorek, J | 1 |
| Hajji, L | 1 |
| Saraiba-Bello, C | 1 |
| Romerosa, A | 1 |
| Segovia-Torrente, G | 1 |
| Serrano-Ruiz, M | 1 |
| Bergamini, P | 1 |
| Canella, A | 1 |
| CERRA, R | 1 |
| PERCESEPE, E | 1 |
| Lentini, A | 1 |
| Abbruzzese, A | 1 |
| Caraglia, M | 1 |
| Marra, M | 1 |
| Beninati, S | 1 |
| Benoehr, P | 1 |
| Krueth, P | 1 |
| Bokemeyer, C | 1 |
| Grenz, A | 1 |
| Osswald, H | 1 |
| Hartmann, JT | 1 |
| Mavligit, GM | 1 |
| Wong, WL | 1 |
| Namba, M | 1 |
| Nishitani, K | 1 |
| Kimoto, T | 1 |
| Cupissol, D | 1 |
| Rey, A | 1 |
| Goldstein, AL | 1 |
| Serrou, B | 1 |
| Mehta, LK | 1 |
| Monney, H | 1 |
| Parrick, J | 1 |
| Hodgkiss, RJ | 1 |
| Israel, BC | 1 |
| Blouin, RA | 1 |
| McIntyre, W | 1 |
| Shedlofsky, SI | 1 |
| Castro, GD | 1 |
| Delgado de Layño, AM | 1 |
| Costantini, MH | 1 |
| Castro, JA | 1 |
| Gennari, C | 1 |
| Francini, G | 1 |
| Galli, M | 1 |
| Lore, F | 1 |
| Tuckey, JA | 1 |
| Parry, BR | 1 |
| McCall, JL | 1 |
| Mourelatos, D | 1 |
| Kourakis, A | 1 |
| Dozi-Vassiliades, J | 1 |
| Tsiouris, J | 1 |
| Hatzitheodoridou, P | 1 |
| Schulz, FH | 1 |
| Abell, CW | 1 |
| Monahan, TM | 1 |
| Wolberg, WH | 1 |
| Richards, W | 1 |
6 reviews available for theophylline and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
[Coffee and cancer].
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Anticarcinogenic Agents; Caffeine; Cell Trans | 2008 |
Protein-polyamine conjugation by transglutaminase in cancer cell differentiation: review article.
Topics: Animals; Cell Differentiation; Humans; Neoplasms; Polyamines; Proteins; Theophylline; Transglutamina | 2004 |
Methylxanthines in surgery: a bright future?
Topics: Humans; Neoplasms; Pentoxifylline; Respiratory Distress Syndrome; Shock, Septic; Surgical Procedures | 1992 |
The role of adenosine 3',5'-cyclic monophosphate in the regulation of mammalian cell division.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Cell Division; Cell Line; Cell Transformation, Neoplastic; | 1973 |
Differential diagnosis of childhood asthma.
Topics: Age Factors; Asthma; Child; Child Health Services; Child, Institutionalized; Cystic Fibrosis; Defici | 1974 |
4 trials available for theophylline and Neoplasms
| Article | Year |
|---|---|
The protective effect of theophyline in cisplatin nephrotoxicity.
Topics: Aged; Antineoplastic Agents; Cisplatin; Cross-Sectional Studies; Double-Blind Method; Female; Humans | 2014 |
The efficacy of theophylline in preventing cisplatin-related nephrotoxicity in patients with cancer.
Topics: Acute Kidney Injury; Adult; Aged; Antineoplastic Agents; Cisplatin; Creatinine; Cystatin C; Drug Mon | 2016 |
Nephroprotection by theophylline in patients with cisplatin chemotherapy: a randomized, single-blinded, placebo-controlled trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, | 2005 |
Effects of interferon-alpha monotherapy on hepatic drug metabolism in cancer patients.
Topics: Aged; Antipyrine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Female; Hexoba | 1993 |
14 other studies available for theophylline and Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Fragment-based design, synthesis and biological evaluation of theophylline derivatives as ATAD2 inhibitors in BT-549 cells.
Topics: Adenosine Triphosphatases; ATPases Associated with Diverse Cellular Activities; Cell Proliferation; | 2023 |
Natural compounds in the human diet and their ability to bind mutagens prevents DNA-mutagen intercalation.
Topics: Acridine Orange; Antineoplastic Agents; Biophysical Phenomena; Caffeine; Carcinogens; Chlorophyll; C | 2010 |
Water-soluble Cp ruthenium complex containing 1,3,5-triaza-7-phosphaadamantane and 8-thiotheophylline derivatives: synthesis, characterization, and antiproliferative activity.
Topics: Adamantane; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; Crystallography, | 2011 |
[Clinical study of the use of a drug containing a combination of chlorpromazine, gardenal and theophylline-ethylenediamine in patients of malignant neoplasms].
Topics: Aminophylline; Biomedical Research; Chlorpromazine; Electroencephalography; Humans; Neoplasms; Pheno | 1958 |
Partial restoration of local GVH reaction in cancer patients by depletion of theophylline-sensitive suppressor T-cells.
Topics: Animals; Cell Separation; Graft vs Host Reaction; Humans; Leukocyte Count; Male; Neoplasms; Probabil | 1982 |
Effects of theophylline on the cell growth of normal and malignant human cells transformed in culture.
Topics: Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cyclic AMP; DNA; DNA, Neoplasm; Fib | 1980 |
Decrease of tumor growth in mice after intravenous thymosin-treated bone marrow cell injection.
Topics: Animals; Bone Marrow Transplantation; Cell Division; Levamisole; Male; Methylcholanthrene; Mice; Mic | 1982 |
Potential bioreductively activated hypoxia probes and post-irradiation radiosensitizers related to NITP.
Topics: Biomarkers; Cell Hypoxia; Cells, Cultured; Magnetic Resonance Spectroscopy; Neoplasms; Nitroimidazol | 1995 |
Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects.
Topics: Acetaldehyde; Alcohol Drinking; Allopurinol; Animals; Antimetabolites; Caffeine; Carcinogens; Chroma | 2001 |
Urinary excretion of cyclic adenosine 3',5'-monophosphate and cyclic guanosine 3',5'-monophosphate in malignancy.
Topics: Adult; Aged; Cyclic AMP; Cyclic GMP; Female; Glucagon; Humans; Male; Middle Aged; Neoplasms; Theophy | 1978 |
Synergistic induction of sister-chromatid exchanges in lymphocytes from normal subjects and from patients under cytostatic therapy by inhibitors of poly(ADP-ribose)polymerase and antitumour agents.
Topics: Antineoplastic Agents; DNA Repair; Drug Synergism; Humans; In Vitro Techniques; Lymphocytes; NAD+ Nu | 1985 |
[Some problems of practical geriatrics].
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Analgesics; Cardiovascular Diseases; Chemical and Dr | 1974 |
Inhibition of leukocyte migration by human tumors. Effect on patient survival.
Topics: Breast Neoplasms; Bucladesine; Cell Migration Inhibition; Colonic Neoplasms; Culture Media; Culture | 1974 |