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theophylline and Necrosis

theophylline has been researched along with Necrosis in 16 studies

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"These investigators have previously developed a model for inducing aortic aneurysms by administering theophylline or caffeine to embryonic chicks."7.66Light- and electron-microscopic observations of theophylline-induced aortic aneurysms in embryonic chicks. ( Bruyere, HJ; Gilbert, EF; Matsuoka, R; Uno, H; Yokoyama, H, 1983)
"At external examination, skin blisters on regions exposed to pressure were distinctive."5.31Coma blisters in a case of fatal theophylline intoxication. ( Sperhake, JP; Tsokos, M, 2002)
"We assessed the effects of the adenosine antagonist 8-(p-sulfophenyl)theophylline (SPT) and adenosine on myocardial infarct size and the incidence of ventricular arrhythmias in five groups of rats: control (nonpreconditioned)+vehicle, control+SPT, preconditioned+vehicle, preconditioned+SPT, and control (nonpreconditioned)+adenosine."3.68The cardioprotective effects of ischemic 'preconditioning' are not mediated by adenosine receptors in rat hearts. ( Kloner, RA; Li, Y, 1993)
"There are pronounced interindividual differences in the neurotoxicity of theophylline in humans as reflected by the wide range of plasma theophylline concentrations associated with the occurrence of life-threatening, generalized seizures in patients treated with this widely used bronchodilator."3.67Kinetics of drug action in disease states. XIX. Effect of experimental liver disease on the neurotoxicity of theophylline in rats. ( Levy, G; Ramzan, IM; Yasuhara, M, 1987)
"We investigated the influence of the adenosine antagonist theophylline on the degree of hippocampal cell damage in the Mongolian gerbil following brief periods of forebrain ischemia."3.67Effect of theophylline on ischemically induced hippocampal damage in Mongolian gerbils: a behavioral and histopathological study. ( Hinze, HJ; Keil, M; Rudolphi, KA, 1987)
"These investigators have previously developed a model for inducing aortic aneurysms by administering theophylline or caffeine to embryonic chicks."3.66Light- and electron-microscopic observations of theophylline-induced aortic aneurysms in embryonic chicks. ( Bruyere, HJ; Gilbert, EF; Matsuoka, R; Uno, H; Yokoyama, H, 1983)
"At external examination, skin blisters on regions exposed to pressure were distinctive."1.31Coma blisters in a case of fatal theophylline intoxication. ( Sperhake, JP; Tsokos, M, 2002)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199011 (68.75)18.7374
1990's2 (12.50)18.2507
2000's2 (12.50)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hashemi-Niasari, F1
Rabbani-Chadegani, A1
Razmi, M1
Fallah, S1
Tsokos, M1
Sperhake, JP1
KOERLOF, B1
UGLAND, O1
Barilli, A1
Visigalli, R1
Sala, R1
Gazzola, GC1
Parolari, A1
Tremoli, E1
Bonomini, S1
Simon, A1
Closs, EI1
Dall'Asta, V1
Bussolati, O1
Yokoyama, H1
Matsuoka, R1
Bruyere, HJ1
Gilbert, EF1
Uno, H1
Li, Y1
Kloner, RA1
Ebbesen, P1
Strubelt, O2
Hoffmann, A1
Siegers, CP2
Sierra-Callejas, JL1
Abramovici, A1
Goren, G1
Gassner, S1
Urca, J1
Liban, E1
Lloyd, DM1
Payne, SP1
Tomson, CR1
Barnes, MR1
Allen, MJ1
Ramzan, IM1
Yasuhara, M1
Levy, G1
Rudolphi, KA1
Keil, M1
Hinze, HJ1
Martorana, PA1
Bellini, O1
Glässer, AH1
Arturson, G1
Khanna, NN1
Wegener, F1

Other Studies

16 other studies available for theophylline and Necrosis

ArticleYear
Synergy of theophylline reduces necrotic effect of berberine, induces cell cycle arrest and PARP, HMGB1, Bcl-2 family mediated apoptosis in MDA-MB-231 breast cancer cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 106

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Berberine; Br

2018
Coma blisters in a case of fatal theophylline intoxication.
    The American journal of forensic medicine and pathology, 2002, Volume: 23, Issue:3

    Topics: Adult; Blister; Coma; Drug Overdose; Eccrine Glands; Female; Humans; Necrosis; Theophylline

2002
[FLAP GRAFTING AND FLAP NECROSIS. IMPROVEMENT OF CIRCULATION IN SKIN FLAPS WITH COMPLAMIN AND DICUMAROL: ANIMAL EXPERIMENTS].
    Nordisk medicin, 1964, Oct-08, Volume: 72

    Topics: Animal Experimentation; Animals; Blood Circulation; Dicumarol; Humans; Necrosis; Niacin; Nicotinic A

1964
In human endothelial cells rapamycin causes mTORC2 inhibition and impairs cell viability and function.
    Cardiovascular research, 2008, Jun-01, Volume: 78, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Blotting, Western; Cardiovascular Agents; Carrier P

2008
Light- and electron-microscopic observations of theophylline-induced aortic aneurysms in embryonic chicks.
    The American journal of pathology, 1983, Volume: 112, Issue:3

    Topics: Animals; Aorta; Aortic Aneurysm; Chick Embryo; Collagen; Elastic Tissue; Endothelium; Heart; Heart S

1983
The cardioprotective effects of ischemic 'preconditioning' are not mediated by adenosine receptors in rat hearts.
    Circulation, 1993, Volume: 87, Issue:5

    Topics: Adenosine; Animals; Arrhythmias, Cardiac; Female; Heart; Hemodynamics; Myocardial Ischemia; Myocardi

1993
Myocardial degeneration in mice treated with dibutyryl cyclic AMP and/or theophylline.
    Virchows Archiv. A, Pathological anatomy and histology, 1976, Dec-07, Volume: 372, Issue:2

    Topics: Animals; Bucladesine; Cardiomyopathies; Female; Leukemia, Experimental; Mice; Mice, Inbred AKR; Mice

1976
On the pathogenesis of cardiac necroses induced by theophylline and caffeine.
    Acta pharmacologica et toxicologica, 1976, Volume: 39, Issue:3

    Topics: Animals; Blood Pressure; Caffeine; Calcium; Gallopamil; Heart; Heart Rate; Isoproterenol; Male; Myoc

1976
[Pathophysiological aspects of experimental fat necrosis and its relation to acute pancreatic necrosis].
    Harefuah, 1976, Oct-15, Volume: 91, Issue:8

    Topics: Animals; Epinephrine; Fat Necrosis; Lipase; Models, Biological; Necrosis; Pancreas; Pancreatic Disea

1976
Acute compartment syndrome secondary to theophylline overdose.
    Lancet (London, England), 1990, Aug-04, Volume: 336, Issue:8710

    Topics: Acute Disease; Compartment Syndromes; Female; Humans; Leg; Middle Aged; Muscles; Necrosis; Theophyll

1990
Kinetics of drug action in disease states. XIX. Effect of experimental liver disease on the neurotoxicity of theophylline in rats.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Acute Kidney Injury; Animals; Carbon Tetrachloride Poisoning; Cholestasis, Extrahepatic; Female; Kin

1987
Effect of theophylline on ischemically induced hippocampal damage in Mongolian gerbils: a behavioral and histopathological study.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1987, Volume: 7, Issue:1

    Topics: Adenosine; Animals; Behavior, Animal; Brain Ischemia; Cerebrovascular Circulation; Gerbillinae; Hipp

1987
The role of cyclic AMP in isoprenaline-induced cardiac necroses in the rat.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23, Issue:3

    Topics: Adenine Nucleotides; Animals; Cyclic AMP; Heart Diseases; Isoproterenol; Male; Myocardium; Necrosis;

1971
Absence of potentiation of phenylephrine-induced cardiac necroses by theophylline. Selective inhibition by dihydroergocryptine and nicergoline.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:9

    Topics: Adrenergic alpha-Antagonists; Animals; Bromine; Drug Synergism; Ergolines; Ergoloid Mesylates; Heart

1972
The effects of hyperbaric oxygen, dimethyl sulfoxide and Complamin on the survival of experimental skin flaps.
    Scandinavian journal of plastic and reconstructive surgery, 1970, Volume: 4, Issue:1

    Topics: Animals; Dimethyl Sulfoxide; Hyperbaric Oxygenation; Male; Necrosis; Nicotinic Acids; Rats; Regional

1970
[Hepatotoxicity of caffeine and theophylline].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:4

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeine; Carbon Tetrachloride Poisoning

1970