theophylline has been researched along with Myocardial Ischemia in 58 studies
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of varying concentrations of theophylline on exercise-induced myocardial ischemia were evaluated in patients with stable coronary artery disease." | 9.07 | Effects of intravenous theophylline on exercise-induced myocardial ischemia: II. A concentration-dependent phenomenon. ( Ahlberg, AW; Barbour, MM; Cloutier, DJ; Garber, CE; Heller, GV; McClellan, JR, 1993) |
| "Theophylline has been shown to delay the onset of myocardial ischemia and to prolong exercise duration." | 9.07 | Effects of intravenous theophylline on exercise-induced myocardial ischemia. I. Impact on the ischemic threshold. ( Barbour, MM; Corning, JJ; Dweik, RB; Garber, CE; Heller, GV; McClellan, JR, 1993) |
| "In this study, the antiarrhythmic effects of adenosine on ventricular fibrillation during global (low flow) ischemia were evaluated in isolated guinea pig hearts perfused by the method of Langendorff." | 7.71 | Antiarrhythmic effects of adenosine on ischemia-induced ventricular fibrillation. ( Brodmann, M; Lueger, A; Stark, G; Stark, U, 2001) |
| "Persisting coronary vasoconstrictor tone that is responsive to exogenous adenosine administration has been demonstrated during myocardial ischemia." | 7.68 | Inhibition of adenosine-mediated coronary vasodilation exacerbates myocardial ischemia during exercise. ( Bache, RJ; Homans, DC; Laxson, DD, 1993) |
| "The effects of varying concentrations of theophylline on exercise-induced myocardial ischemia were evaluated in patients with stable coronary artery disease." | 5.07 | Effects of intravenous theophylline on exercise-induced myocardial ischemia: II. A concentration-dependent phenomenon. ( Ahlberg, AW; Barbour, MM; Cloutier, DJ; Garber, CE; Heller, GV; McClellan, JR, 1993) |
| "Theophylline has been shown to delay the onset of myocardial ischemia and to prolong exercise duration." | 5.07 | Effects of intravenous theophylline on exercise-induced myocardial ischemia. I. Impact on the ischemic threshold. ( Barbour, MM; Corning, JJ; Dweik, RB; Garber, CE; Heller, GV; McClellan, JR, 1993) |
| "Previous studies indicate that adenosine supplementation or nitric oxide synthase (NOS) inhibition during reperfusion exert protective effects against myocardial ischemia-reperfusion (I/R) injury." | 3.74 | Delayed 24 hours Nomega-nitro-L-arginine methyl ester injection induces pharmacological cardioprotection against reperfusion injury. ( Bouhaddi, M; Davani, S; Kantelip, JP; Reyssie, H; Rochette, L; Royer, B; Vergely, C, 2007) |
| "In this study, the antiarrhythmic effects of adenosine on ventricular fibrillation during global (low flow) ischemia were evaluated in isolated guinea pig hearts perfused by the method of Langendorff." | 3.71 | Antiarrhythmic effects of adenosine on ischemia-induced ventricular fibrillation. ( Brodmann, M; Lueger, A; Stark, G; Stark, U, 2001) |
| " In additional experimental groups, 8 sulfophenyl-theophylline (SPT, 10 mg/kg), an adenosine receptor inhibitor, was intravenously injected before the 40 min myocardial ischemia (SPT, MPC + SPT and RPC + SPT groups, respectively)." | 3.70 | Renal ischemia/reperfusion remotely improves myocardial energy metabolism during myocardial ischemia via adenosine receptors in rabbits: effects of "remote preconditioning". ( Inubushi, T; Kinoshita, M; Mitsunami, K; Morikawa, S; Nakae, I; Takaoka, A; Yabe, T, 1999) |
| "Persisting coronary vasoconstrictor tone that is responsive to exogenous adenosine administration has been demonstrated during myocardial ischemia." | 3.68 | Inhibition of adenosine-mediated coronary vasodilation exacerbates myocardial ischemia during exercise. ( Bache, RJ; Homans, DC; Laxson, DD, 1993) |
| "We conclude that 1) in sustained myocardial ischemia, SOD treatment attenuates ischemic injury caused by coronary microembolization by restoration of 5'-nucleotidase activity and augmentation of adenosine release; 2) this beneficial effect of SOD is observed even after coronary microembolization; and 3) the beneficial effects of SOD are attributable to coronary vasodilation produced by augmented adenosine release." | 3.68 | Superoxide dismutase restores contractile and metabolic dysfunction through augmentation of adenosine release in coronary microembolization. ( Hori, M; Inoue, M; Kamada, T; Kitakaze, M; Sato, H; Takashima, S, 1993) |
| "We assessed the effects of the adenosine antagonist 8-(p-sulfophenyl)theophylline (SPT) and adenosine on myocardial infarct size and the incidence of ventricular arrhythmias in five groups of rats: control (nonpreconditioned)+vehicle, control+SPT, preconditioned+vehicle, preconditioned+SPT, and control (nonpreconditioned)+adenosine." | 3.68 | The cardioprotective effects of ischemic 'preconditioning' are not mediated by adenosine receptors in rat hearts. ( Kloner, RA; Li, Y, 1993) |
| "To test the hypothesis that the endothelium-derived relaxing factor (EDRF) contributes to coronary vasodilation induced by myocardial ischemia, we examined the effect of NG-nitro-L-arginine (a potent and selective inhibitor of EDRF release) on the coronary reactive hyperemic response in the open-chest dogs." | 3.68 | NG-nitro-L-arginine attenuates flow debt repayment in the reactive hyperemic response of the open-chest dog coronary artery: contribution of endothelium-derived relaxing factor. ( Kajikawa, Y; Kusachi, S; Marutani, M; Tsuji, T; Yamasaki, S, 1992) |
| "Adenosine A1 receptors were blocked with 8-p-sulfophenyl theophylline (8-SPT; 20 microM)." | 1.30 | Adenosine receptor blockade enhance glycolysis in hypoperfused guinea-pig myocardium. ( Downey, HF; Gao, ZP; He, MX; Mallet, RT; Sun, J, 1997) |
| "Adenosine has several potentially cardioprotective effects." | 1.30 | Importance of endogenous adenosine during ischemia and reperfusion in neonatal porcine hearts. ( Grund, F; Ilebekk, A; Jynge, P; Kirkebøen, KA; Offstad, J; Sommerschild, HT, 1997) |
| "Adenosine has several potentially cardioprotective effects including vasodilatation, reduction in heart rate and alterations in metabolism." | 1.30 | Elevated levels of endogenous adenosine alter metabolism and enhance reduction in contractile function during low-flow ischemia: associated changes in expression of Ca(2+)-ATPase and phospholamban. ( Deindl, E; Ilebekk, A; Jynge, P; Kirkebøen, KA; Lunde, PK; Sommerschild, HT, 1999) |
| "(3) Treatment with acadesine (2." | 1.29 | Acadesine extends the window of protection afforded by ischaemic preconditioning. ( Burckhartt, B; Cohen, MV; Downey, JM; Mullane, KM; Tsuchida, A; Yang, XM, 1994) |
| "Adenosine has been identified as a factor in the protection afforded against regional tissue necrosis by such preconditioning." | 1.29 | Improved functional recovery by ischaemic preconditioning is not mediated by adenosine in the globally ischaemic isolated rat heart. ( Cave, AC; Collis, CS; Downey, JM; Hearse, DJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.72) | 18.7374 |
| 1990's | 47 (81.03) | 18.2507 |
| 2000's | 8 (13.79) | 29.6817 |
| 2010's | 2 (3.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scalone, G | 1 |
| Coviello, I | 1 |
| Barone, L | 1 |
| Pisanello, C | 1 |
| Sestito, A | 1 |
| Lanza, GA | 1 |
| Crea, F | 3 |
| Abd-Elfattah, AS | 1 |
| Ding, M | 1 |
| Jessen, ME | 1 |
| Wechsler, AS | 1 |
| Bradamante, S | 1 |
| Barenghi, L | 1 |
| Piccinini, F | 1 |
| Bertelli, AA | 1 |
| De Jonge, R | 2 |
| Beemster, P | 1 |
| De Jong, JW | 2 |
| Efimova, NIu | 1 |
| Chernov, VI | 1 |
| Efimova, IIu | 1 |
| Akhmedov, ShD | 1 |
| Podoksenov, IuK | 1 |
| Lishmanov, IuB | 1 |
| GHIA, G | 1 |
| MEREU, D | 1 |
| Asanuma, H | 1 |
| Minamino, T | 4 |
| Sanada, S | 1 |
| Ogita, H | 1 |
| Kim, J | 1 |
| Fujita, M | 1 |
| Hirata, A | 1 |
| Tsukamoto, O | 1 |
| Ogai, A | 1 |
| Node, K | 3 |
| Hori, M | 6 |
| Tomoike, H | 1 |
| Kitakaze, M | 5 |
| Davani, S | 1 |
| Vergely, C | 1 |
| Royer, B | 1 |
| Bouhaddi, M | 1 |
| Reyssie, H | 1 |
| Rochette, L | 1 |
| Kantelip, JP | 1 |
| Armstrong, S | 4 |
| Downey, JM | 8 |
| Ganote, CE | 4 |
| Morioka, T | 1 |
| Shinozaki, Y | 1 |
| Chujo, M | 1 |
| Mori, H | 1 |
| Takeda, H | 1 |
| Inoue, M | 2 |
| Gao, ZP | 2 |
| Downey, HF | 2 |
| Fan, WL | 1 |
| Mallet, RT | 2 |
| Barbour, MM | 2 |
| Garber, CE | 2 |
| Ahlberg, AW | 1 |
| Cloutier, DJ | 1 |
| McClellan, JR | 2 |
| Heller, GV | 2 |
| Vegh, A | 1 |
| Papp, JG | 1 |
| Parratt, JR | 1 |
| Rynning, SE | 1 |
| Brunvand, H | 1 |
| Birkeland, S | 1 |
| Hexeberg, E | 1 |
| Grong, K | 1 |
| Bugge, E | 1 |
| Ytrehus, K | 1 |
| Liu, GS | 1 |
| Richards, SC | 1 |
| Olsson, RA | 1 |
| Mullane, K | 1 |
| Walsh, RS | 3 |
| Hoshida, S | 1 |
| Kuzuya, T | 2 |
| Nishida, M | 1 |
| Yamashita, N | 1 |
| Oe, H | 1 |
| Kamada, T | 2 |
| Tada, M | 1 |
| Tsuchida, A | 2 |
| Daly, JJ | 1 |
| Thornton, JD | 1 |
| Cohen, MV | 4 |
| Baxter, GF | 2 |
| Marber, MS | 1 |
| Patel, VC | 1 |
| Yellon, DM | 2 |
| Bertolet, BD | 1 |
| Belardinelli, L | 1 |
| Kerensky, R | 1 |
| Hill, JA | 1 |
| Zhao, ZQ | 1 |
| Nakanishi, K | 1 |
| McGee, DS | 1 |
| Tan, P | 1 |
| Vinten-Johansen, J | 1 |
| Yang, XM | 1 |
| Burckhartt, B | 1 |
| Mullane, KM | 1 |
| Laxson, DD | 2 |
| Homans, DC | 1 |
| Bache, RJ | 2 |
| Schwartz, LM | 1 |
| Raschke, P | 1 |
| Becker, BF | 1 |
| Gerlach, E | 1 |
| Duncker, DJ | 2 |
| Lindstrom, P | 1 |
| Urabe, K | 1 |
| Miura, T | 2 |
| Iwamoto, T | 1 |
| Ogawa, T | 1 |
| Goto, M | 3 |
| Sakamoto, J | 2 |
| Iimura, O | 1 |
| Cave, AC | 1 |
| Collis, CS | 1 |
| Hearse, DJ | 1 |
| Gaspardone, A | 2 |
| Iamele, M | 1 |
| Tomai, F | 2 |
| Versaci, F | 1 |
| Pellegrino, A | 1 |
| Chiariello, L | 2 |
| Gioffré, PA | 2 |
| Takashima, S | 1 |
| Sato, H | 1 |
| Dweik, RB | 1 |
| Corning, JJ | 1 |
| Li, Y | 1 |
| Kloner, RA | 1 |
| Pisarenko, OI | 1 |
| Tskitishvily, OV | 1 |
| Studneva, IM | 1 |
| Serebryakova, LI | 1 |
| Korchazhkina, OV | 1 |
| Bouchard, JF | 1 |
| Lamontagne, D | 1 |
| van Wylen, DG | 1 |
| Hashimura, K | 1 |
| Kijima, Y | 1 |
| Matsu-ura, Y | 1 |
| Ueda, T | 1 |
| Kato, Y | 1 |
| Mori, I | 1 |
| Sun, J | 1 |
| He, MX | 1 |
| Gryglewski, RJ | 1 |
| Chlopicki, S | 1 |
| Niezabitowski, P | 1 |
| Jakubowski, A | 1 |
| Lomnicka, M | 1 |
| Zaman, MJ | 1 |
| Kerac, M | 1 |
| Matherne, GP | 1 |
| Linden, J | 1 |
| Byford, AM | 1 |
| Gauthier, NS | 1 |
| Headrick, JP | 1 |
| Danesi, A | 1 |
| Perino, M | 1 |
| Ghini, AS | 1 |
| Ruggeri, G | 1 |
| Askenasy, N | 1 |
| Navon, G | 1 |
| Sommerschild, HT | 2 |
| Grund, F | 1 |
| Offstad, J | 1 |
| Jynge, P | 2 |
| Ilebekk, A | 2 |
| Kirkebøen, KA | 2 |
| Ismail, JA | 1 |
| McDonough, KH | 1 |
| Miki, T | 1 |
| Bünger, R | 1 |
| Suzuki, K | 1 |
| Shimamoto, K | 1 |
| Cohen, G | 1 |
| Shirai, T | 1 |
| Weisel, RD | 1 |
| Rao, V | 1 |
| Merante, F | 1 |
| Tumiati, LC | 1 |
| Mohabeer, MK | 1 |
| Borger, MA | 1 |
| Li, RK | 1 |
| Mickle, DA | 1 |
| Takaoka, A | 1 |
| Nakae, I | 1 |
| Mitsunami, K | 1 |
| Yabe, T | 1 |
| Morikawa, S | 1 |
| Inubushi, T | 1 |
| Kinoshita, M | 1 |
| Schreieck, J | 1 |
| Richardt, G | 1 |
| Lunde, PK | 1 |
| Deindl, E | 1 |
| Komamura, K | 1 |
| Kosaka, H | 1 |
| Yamamoto, M | 1 |
| Egashira, K | 1 |
| Arimura, K | 1 |
| Tada, H | 1 |
| Shimokawa, H | 1 |
| Takeshita, A | 1 |
| Stark, U | 1 |
| Brodmann, M | 1 |
| Lueger, A | 1 |
| Stark, G | 1 |
| Schaefer, S | 1 |
| Correa, SD | 1 |
| Valente, RJ | 1 |
| Laslett, LJ | 1 |
| Liem, DA | 1 |
| Verdouw, PD | 1 |
| Ploeg, H | 1 |
| Kazim, S | 1 |
| Marutani, M | 1 |
| Kusachi, S | 1 |
| Kajikawa, Y | 1 |
| Yamasaki, S | 1 |
| Tsuji, T | 1 |
7 trials available for theophylline and Myocardial Ischemia
| Article | Year |
|---|---|
Brief low-workload myocardial ischaemia induces protection against exercise-related increase of platelet reactivity in patients with coronary artery disease.
Topics: Aged; Coronary Artery Disease; Cross-Over Studies; Exercise; Exercise Test; Female; Flow Cytometry; | 2010 |
Effects of intravenous theophylline on exercise-induced myocardial ischemia: II. A concentration-dependent phenomenon.
Topics: Adenosine; Aged; Blood Pressure; Cardiac Complexes, Premature; Chronic Disease; Coronary Disease; Do | 1993 |
Bamiphylline improves exercise-induced myocardial ischemia through a novel mechanism of action.
Topics: Aged; Coronary Angiography; Echocardiography; Exercise Test; Female; Hemodynamics; Humans; Male; Mid | 1993 |
Effects of intravenous theophylline on exercise-induced myocardial ischemia. I. Impact on the ischemic threshold.
Topics: Blood Pressure; Double-Blind Method; Electrocardiography; Exercise; Heart; Heart Rate; Humans; Infus | 1993 |
Effect of theophylline on adaptation of the heart to myocardial ischemia during percutaneous transluminal coronary angioplasty in patients with stable angina pectoris.
Topics: Adaptation, Physiological; Adult; Aged; Aged, 80 and over; Angina Pectoris; Angioplasty, Balloon, Co | 1997 |
Effects of A1 adenosine receptor blockade on the warm-up phenomenon.
Topics: Aged; Double-Blind Method; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Pu | 1997 |
Blockade of adenosine receptors with aminophylline limits ischemic preconditioning in human beings.
Topics: Aminophylline; Angioplasty; Cardiotonic Agents; Coronary Disease; Electrocardiography; Female; Human | 2001 |
51 other studies available for theophylline and Myocardial Ischemia
| Article | Year |
|---|---|
On-pump inhibition of es-ENT1 nucleoside transporter and adenosine deaminase during aortic crossclamping entraps intracellular adenosine and protects against reperfusion injury: role of adenosine A1 receptor.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Chromatography, High Pressure Liquid; Constriction | 2012 |
Resveratrol provides late-phase cardioprotection by means of a nitric oxide- and adenosine-mediated mechanism.
Topics: Adenosine; Animals; Cardiotonic Agents; Coronary Circulation; Enzyme Inhibitors; Heart; In Vitro Tec | 2003 |
[Pharmacological prevention of cerebrovascular complications in cardiac patients after coronary artery bypass surgery].
Topics: Benzamides; Cerebrovascular Circulation; Cognition Disorders; Coronary Artery Bypass; Drug Combinati | 2003 |
[CLINICAL OBSERVATIONS AND THERAPEUTIC RESULTS IN SUBJECTS WITH ISCHEMIC CARDIOPATHY TREATED WITH AN ENZYME COMPLEX ASSOCIATED WITH A VASODILATOR DRUG].
Topics: Adenosine Triphosphate; Coronary Disease; Drug Therapy; Electrocardiography; Flavin Mononucleotide; | 1964 |
A calcium channel blocker amlodipine increases coronary blood flow via both adenosine- and NO-dependent mechanisms in ischemic hearts.
Topics: Adenosine; Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Do | 2005 |
Delayed 24 hours Nomega-nitro-L-arginine methyl ester injection induces pharmacological cardioprotection against reperfusion injury.
Topics: Adenosine; Animals; Arginine; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Enzyme Inh | 2007 |
Preconditioning of isolated rabbit cardiomyocytes: induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor.
Topics: Adenosine; Animals; Cell Size; Cell Survival; Cells, Cultured; Glucose; Heart; Myocardial Ischemia; | 1994 |
Adenosine receptor specificity in preconditioning of isolated rabbit cardiomyocytes: evidence of A3 receptor involvement.
Topics: Adenosine; Animals; Antihypertensive Agents; Cells, Cultured; Glucose; Myocardial Infarction; Myocar | 1994 |
In vitro ischaemic preconditioning of isolated rabbit cardiomyocytes: effects of selective adenosine receptor blockade and calphostin C.
Topics: Animals; In Vitro Techniques; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Naphth | 1995 |
Bidirectional effects of aminophylline on myocardial ischemia.
Topics: Adenosine; Aminophylline; Animals; Coronary Circulation; Dogs; Heart; Lactates; Lactic Acid; Myocard | 1995 |
Does interstitial adenosine mediate acute hibernation of guinea pig myocardium?
Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; C | 1995 |
Pronounced antiarrhythmic effects of preconditioning in anaesthetized dogs: is adenosine involved?
Topics: Adenosine; Anesthesia, General; Animals; Arrhythmias, Cardiac; Blood Flow Velocity; Blood Pressure; | 1995 |
Endogenous adenosine attenuates myocardial stunning by antiadrenergic effects exerted during ischemia and not during reperfusion.
Topics: Adenosine; Animals; Cats; Coronary Circulation; Doxazosin; Heart; Hemodynamics; Male; Myocardial Con | 1995 |
Ischaemic preconditioning is protein kinase C dependent but not through stimulation of alpha adrenergic or adenosine receptors in the isolated rat heart.
Topics: Alkaloids; Animals; Benzophenanthridines; In Vitro Techniques; Male; Myocardial Infarction; Myocardi | 1995 |
Evidence that the adenosine A3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart.
Topics: Adenosine; Animals; Antihypertensive Agents; Female; In Vitro Techniques; Male; Myocardial Infarctio | 1994 |
Adenosine blockade during reperfusion reverses the infarct limiting effect in preconditioned canine hearts.
Topics: Animals; Dogs; Female; Leukocyte Count; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium | 1994 |
Ketamine-xylazine anaesthesia permits a KATP channel antagonist to attenuate preconditioning in rabbit myocardium.
Topics: Animals; Glyburide; Guanidines; Ketamine; Myocardial Infarction; Myocardial Ischemia; Myocardium; Pi | 1994 |
Adenosine receptor involvement in a delayed phase of myocardial protection 24 hours after ischemic preconditioning.
Topics: Adenosine; Animals; Heart; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardia | 1994 |
Adenosine blockade as primary therapy for ischemia-induced accelerated idioventricular rhythm: rationale and potential clinical application.
Topics: Adenosine; Aged; Arrhythmia, Sinus; Bradycardia; Female; Humans; Male; Myocardial Ischemia; Streptok | 1994 |
A1 receptor mediated myocardial infarct size reduction by endogenous adenosine is exerted primarily during ischaemia.
Topics: Adenosine; Adrenergic alpha-1 Receptor Antagonists; Animals; Myocardial Infarction; Myocardial Ische | 1994 |
Acadesine extends the window of protection afforded by ischaemic preconditioning.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Female; Male; Myocardial Infarction; Myocardial Isch | 1994 |
Inhibition of adenosine-mediated coronary vasodilation exacerbates myocardial ischemia during exercise.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dog | 1993 |
Adenosine contributes to neutrophil-mediated loss of myocardial function in post-ischemic guinea-pig hearts.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Flow Velocity; Cardiac Output; Coronary Circulation; | 1993 |
Endogenous adenosine and coronary vasoconstriction in hypoperfused myocardium during exercise.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Animals; Coronary Ves | 1993 |
Adenosine and A1 selective agonists offer minimal protection against ischaemic injury to isolated rat cardiomyocytes.
Topics: Adenosine; Animals; Carbachol; Cell Death; Cells, Cultured; Iodoacetates; Iodoacetic Acid; Isoproter | 1993 |
Preconditioning enhances myocardial resistance to postischaemic myocardial stunning via adenosine receptor activation.
Topics: Animals; Disease Models, Animal; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reper | 1993 |
Improved functional recovery by ischaemic preconditioning is not mediated by adenosine in the globally ischaemic isolated rat heart.
Topics: Adenosine; Animals; Coronary Circulation; Disease Models, Animal; Male; Myocardial Contraction; Myoc | 1993 |
Superoxide dismutase restores contractile and metabolic dysfunction through augmentation of adenosine release in coronary microembolization.
Topics: 5'-Nucleotidase; Adenosine; Animals; Coronary Circulation; Dogs; Embolism; Injections; Lactates; Lac | 1993 |
The cardioprotective effects of ischemic 'preconditioning' are not mediated by adenosine receptors in rat hearts.
Topics: Adenosine; Animals; Arrhythmias, Cardiac; Female; Heart; Hemodynamics; Myocardial Ischemia; Myocardi | 1993 |
Hypoxia preconditions rabbit myocardium via adenosine and catecholamine release.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Catecholamines; Heart; Hemodynamics; Hypoxia; In V | 1995 |
Metabolic effects of ischemic preconditioning and adenosine receptor blockade in dogs.
Topics: Adenosine; Animals; Creatine; Dogs; Female; Lactic Acid; Male; Myocardial Ischemia; Purinergic P1 Re | 1996 |
Mechanisms of protection afforded by preconditioning to endothelial function against ischemic injury.
Topics: Adenosine Triphosphate; Animals; Coronary Vessels; Endothelium, Vascular; Glyburide; In Vitro Techni | 1996 |
Attenuated purine production during subsequent ischemia in preconditioned rabbit myocardium is unrelated to the mechanism of protection.
Topics: Adenosine; Animals; Female; Heart; Hemodynamics; Hypoxanthines; In Vitro Techniques; Inosine; Ischem | 1996 |
Adenosine receptor blockade enhance glycolysis in hypoperfused guinea-pig myocardium.
Topics: Adenosine; Animals; Enzyme Activation; Glucose; Glycogen; Glycolysis; Guinea Pigs; In Vitro Techniqu | 1997 |
Ischaemic cardiac hyperaemia: role of nitric oxide and other mediators.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Animals; Coronary Circulation; Cyclic GMP; Cyclooxygenase I | 1996 |
Protection against global ischemia in the rabbit isolated heart 24 hours after transient adenosine A1 receptor activation.
Topics: Adenosine; Animals; Blood Pressure; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; | 1997 |
Transgenic A1 adenosine receptor overexpression increases myocardial resistance to ischemia.
Topics: Adenosine; Analysis of Variance; Animals; Cell Membrane; Coronary Vessels; Female; Heart; Heart Rate | 1997 |
Intermittent ischemia: energy metabolism, cellular volume regulation, adenosine and insights into preconditioning.
Topics: Adenosine; Animals; Cell Size; Creatine; Energy Metabolism; Glyburide; Glycogen; Glycolysis; In Vitr | 1997 |
Importance of endogenous adenosine during ischemia and reperfusion in neonatal porcine hearts.
Topics: Adenosine; Animals; Animals, Newborn; Creatine Kinase; Myocardial Contraction; Myocardial Ischemia; | 1997 |
The role of coronary flow and adenosine in postischemic recovery of septic rat hearts.
Topics: Animals; Bacteremia; Blood Pressure; Coronary Circulation; Escherichia coli Infections; Heart Rate; | 1998 |
Ecto-5'-nucleotidase is not required for ischemic preconditioning in rabbit myocardium in situ.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Pressure; Enzyme Inh | 1998 |
Optimal myocardial preconditioning in a human model of ischemia and reperfusion.
Topics: Adenosine; Dose-Response Relationship, Drug; Humans; Ischemic Preconditioning, Myocardial; Myocardia | 1998 |
Renal ischemia/reperfusion remotely improves myocardial energy metabolism during myocardial ischemia via adenosine receptors in rabbits: effects of "remote preconditioning".
Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Hydrogen-Ion Concentration; Infusions, Intraveno | 1999 |
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiogra | 1999 |
Elevated levels of endogenous adenosine alter metabolism and enhance reduction in contractile function during low-flow ischemia: associated changes in expression of Ca(2+)-ATPase and phospholamban.
Topics: Adenosine; Animals; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cardiotonic Agents; Ener | 1999 |
Intracoronary administration of adenosine triphosphate increases coronary blood flow and attenuates the severity of myocardial ischemic injury in dogs.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Coronary Circulation; Dogs; Enzyme Inhibitors | 1999 |
Ischemic preconditioning and glucose metabolism during low-flow ischemia: role of the adenosine A1 receptor.
Topics: Adenosine; Animals; Glucose; Glycolysis; Ischemic Preconditioning, Myocardial; Male; Myocardial Isch | 1999 |
Coronary vascular K+ATP channels contribute to the maintenance of myocardial perfusion in dogs with pacing-induced heart failure.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relatio | 2000 |
Antiarrhythmic effects of adenosine on ischemia-induced ventricular fibrillation.
Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; | 2001 |
Sites of action of adenosine in interorgan preconditioning of the heart.
Topics: Adenosine; Animals; Blood Pressure; Coronary Vessels; Ganglionic Blockers; Heart Rate; Hexamethonium | 2002 |
NG-nitro-L-arginine attenuates flow debt repayment in the reactive hyperemic response of the open-chest dog coronary artery: contribution of endothelium-derived relaxing factor.
Topics: Adenosine; Animals; Arginine; Coronary Vessels; Dogs; Myocardial Ischemia; Nitric Oxide; Nitroargini | 1992 |