theophylline has been researched along with Muscle Contraction in 465 studies
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Excerpt | Relevance | Reference |
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" Recent studies have shown beneficial effects of an adenosine A(2A) receptor agonist in dt(sz) mutant hamsters, an animal model of paroxysmal dystonia, in which stress and consumption of coffee can precipitate dystonic attacks." | 7.71 | Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia. ( Hamann, M; Richter, A, 2001) |
" Dosing practices that will minimize side effects and toxicity are stressed, along with their management if they do occur." | 6.37 | Theophylline use in asthma. Some current issues. ( Jenne, JW, 1984) |
"Theophylline has been used for decades in the treatment of chronic inflammatory airway diseases." | 5.43 | Bronchodilator and Anti-Inflammatory Action of Theophylline in a Model of Ovalbumin-Induced Allergic Inflammation. ( Kertys, M; Kosutova, P; Mikolka, P; Mokra, D; Mokry, J; Simekova, M; Urbanova, A, 2016) |
"Melatonin treatment strengthened contraction responses, but did not affect relaxation responses in rat tracheal preparations." | 5.38 | The achilles heel in melatonin: asthma. ( Belgin Yildirim, F; Karasu-Minareci, E; Kaya, Y, 2012) |
"Pretreatment with adenosine receptor antagonists, theophylline or 8-cyclopentyl-1,3-dipropyl xanthine (DPCPX) prior to ischemic preconditioning or adenosine preconditioning abolished the protective effects of preconditioning by ischemic preconditioning and adenosine preconditioning." | 5.34 | Ischemic preconditioning modulates ischemia-reperfusion injury in the rat lung: role of adenosine receptors. ( Demiryürek, AT; Gümüşel, B; Lippton, H; Yildiz, G, 2007) |
" Dose-response curves for the effects of adenosine on K+ contractures indicated that at low doses adenosine decreases force and cytoplasmic ionized calcium but that at high concentrations (greater than 3." | 5.27 | Cellular Ca2+ monitored by aequorin in adenosine-mediated smooth muscle relaxation. ( Bradley, AB; Morgan, KG, 1985) |
" In this study, we investigated the effect of caffeine and theophylline--both are nonselective inhibitors of phosphodiesterase--on urinary bladder smooth muscle contractions evoked by acetylcholine." | 3.74 | In vitro reactivity of urinary bladder smooth muscle in rabbits influenced by xanthine derivatives. ( Mokry, J; Nosalova, G, 2008) |
" Recent studies have shown beneficial effects of an adenosine A(2A) receptor agonist in dt(sz) mutant hamsters, an animal model of paroxysmal dystonia, in which stress and consumption of coffee can precipitate dystonic attacks." | 3.71 | Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia. ( Hamann, M; Richter, A, 2001) |
"We examined the effects of theophylline on contractile properties and high-frequency fatigue of canine diaphragm in vitro." | 3.68 | Theophylline minimally alters contractile properties of canine diaphragm in vitro. ( De Bock, V; Decramer, M; Derom, E; Janssens, S, 1990) |
"Tracheal smooth muscle from seven cases of fatal asthma demonstrated an increased contractile response to histamine, acetylcholine, and electrical stimulation of intrinsic cholinergic nerves; impaired relaxation to isoproterenol, and possibly theophylline, was also evident (1)." | 3.68 | Abnormalities in airway smooth muscle in fatal asthma. A comparison between trachea and bronchus. ( Bai, TR, 1991) |
" The rate and amplitude of smooth muscle relaxation at low PO2 were significantly decreased by tolbutamide (5 mmol l-1), which is known to inhibit cyclic AMP-dependent protein kinases." | 3.68 | Evidence for decrease in myofilament responsiveness to Ca2+ during hypoxia in spontaneously active vascular smooth muscle in rats. ( Basilyuk, OV; Soloviev, AI, 1993) |
"Verapamil was found to be an effective inhibitor of isometric tension in in vitro, experimental anaphylaxis in guinea pig trachealis smooth muscle." | 3.66 | Effect of calcium antagonists in experimental asthma. ( Barbero, L; Markowicz, J; Weiss, EB, 1982) |
" In conscious guinea pigs, pirbuterol antagonizes both histamine- and acetylcholine-induced bronchoconstriction and "microshock" anaphylaxis; combinations of pirbuterol and theophylline cause additive effects against histamine-induced bronchoconstriction." | 3.66 | Pirbuterol, a selecttve beta2 adrenergic bronchodilator. ( Barth, WE; Constantine, JW; Moore, PF, 1978) |
"Enprofylline (E) is a xanthine drug that has poor ability to antagonize physiological actions of adenosine." | 2.66 | Effects of theophylline and enprofylline on diaphragmatic contractility. ( Aubier, M; Mal, H; Murciano, D; Pariente, R; Viirès, N, 1987) |
"Our study evaluated whether a dose-response relationship exists for theophylline and diaphragmatic contractility within the usual therapeutic range for theophylline." | 2.66 | Theophylline and diaphragmatic contractility. Investigation of a dose-response relationship. ( Cuddy, PG; Emory, CE; Foxworth, JW; Knudson, SM; Pyszczynski, DR; Reisz, GR, 1988) |
" The effect of theophyllines on skeletal muscle is dose related and animal studies show that any effect in humans, where dosage is limited by toxicity, is likely to be small." | 2.37 | Aminophylline and the respiratory muscles: an alternative view. ( Moxham, J, 1988) |
" Dosing practices that will minimize side effects and toxicity are stressed, along with their management if they do occur." | 2.37 | Theophylline use in asthma. Some current issues. ( Jenne, JW, 1984) |
"Theophylline is known to increase diaphragmatic contractility and reduce fatigue, so in this study, we evaluated the effect of theophylline in patients with prolonged mechanical ventilation." | 1.51 | Effects of theophylline therapy on respiratory muscle strength in patients with prolonged mechanical ventilation: A retrospective cohort study. ( Chu, CM; Hu, HC; Kao, KC; Liu, YC; Yu, TJ, 2019) |
"Theophylline has been used for decades in the treatment of chronic inflammatory airway diseases." | 1.43 | Bronchodilator and Anti-Inflammatory Action of Theophylline in a Model of Ovalbumin-Induced Allergic Inflammation. ( Kertys, M; Kosutova, P; Mikolka, P; Mokra, D; Mokry, J; Simekova, M; Urbanova, A, 2016) |
"Thus β(2)-agonists reduce the anoxia-induced loss of force, leading to partial force recovery." | 1.38 | Effects of β₂-agonists on force during and following anoxia in rat extensor digitorum longus muscle. ( Clausen, T; Fredsted, A; Gissel, H; Ortenblad, N, 2012) |
"Melatonin treatment strengthened contraction responses, but did not affect relaxation responses in rat tracheal preparations." | 1.38 | The achilles heel in melatonin: asthma. ( Belgin Yildirim, F; Karasu-Minareci, E; Kaya, Y, 2012) |
" The efficacy and potency of bronchodilating drugs were obtained from cumulative dose-response curves with efficacy (E(max)) as the maximal relaxant response and potency (-logEC(50)) as the logarithm of the concentration of drug inducing 50% of maximal relaxation." | 1.38 | A comparison of in vitro relaxant responses to ipratropium bromide, β-adrenoceptor agonists and theophylline in feline bronchial smooth muscle. ( Gustin, P; Kirschvink, N; Leemans, J, 2012) |
"Theophylline was administered intravenously in cumulative doses up to 93." | 1.37 | Effects of theophylline on anesthetized malignant hyperthermia-susceptible pigs. ( Fiege, M; Gerbershagen, MU; Kolodzie, K; Wappler, F; Weisshorn, R, 2011) |
"This study investigates the effect of theophylline along the rabbit gastrointestinal tract in comparison with the pharmacodynamic effect produced by the combined application of its three major metabolites." | 1.36 | The gastrointestinal effects that may follow the administration of theophylline reflect the pharmacodynamic profiles of both the parent drug and its metabolites. ( Batzias, GC; Koutsoviti-Papadopoulou, M; Peeters, TL; Psarra, TA, 2010) |
"Endogenous adenosine is an important modulator of intestinal neuro-effector activity, operating in the linear part of the dose-response curve." | 1.36 | Estimation of endogenous adenosine activity at adenosine receptors in guinea-pig ileum using a new pharmacological method. ( Glaumann, C; Grishina, VA; Gustafsson, LE; Nilsson, KF, 2010) |
"Pretreatment with adenosine receptor antagonists, theophylline or 8-cyclopentyl-1,3-dipropyl xanthine (DPCPX) prior to ischemic preconditioning or adenosine preconditioning abolished the protective effects of preconditioning by ischemic preconditioning and adenosine preconditioning." | 1.34 | Ischemic preconditioning modulates ischemia-reperfusion injury in the rat lung: role of adenosine receptors. ( Demiryürek, AT; Gümüşel, B; Lippton, H; Yildiz, G, 2007) |
" However, the dose-response curve against dermorphine inhibition of the response to CCK-8 was bell-shaped and the highest SR concentration also significantly decreased the mu-withdrawal response." | 1.33 | Involvement of the cannabinoid CB1 receptor in the opioid inhibition of the response to cholecystokinin and acute withdrawal response. ( Amico, MC; Morrone, LA; Palmery, M; Romanelli, L; Tucci, P; Valeri, P, 2005) |
" Experiments with adenosine demonstrated that the selected dose of SPT elicited marked rightward shifts in the dose-response curves for both the inotropic and vascular actions." | 1.33 | Acute dilatory and negative inotropic effects of homocysteine are inhibited by an adenosine blocker. ( Boerma, M; Hauer-Jensen, M; Joseph, J; Kennedy, RH; Melchert, RB; Owings, R, 2006) |
"Pre-treatment with motapizone, RP73401, rolipram or the methylxanthine adenosine receptor antagonist, 8-phenyltheophylline, did not significantly decrease responses to either allergen or LTC(4)." | 1.31 | The effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C(4)-induced contractions in passively sensitized human airways. ( Branscheid, D; Dent, G; Magnussen, H; Rabe, KF; Rühlmann, E; Schmidt, DT; Watson, N, 2000) |
"3." | 1.29 | P2-purinoceptors mediating spasm of the isolated uterus of the non-pregnant guinea-pig. ( Hollingsworth, M; Piper, AS, 1996) |
"Theophylline (1 mM) was subsequently added to one muscle bundle and, after 15 min, twitches were repeated." | 1.29 | Mechanism of theophylline-induced inotropic effects on foreshortened canine diaphragm. ( Decramer, M; Gayan-Ramirez, G; Himpens, B; Janssens, S, 1995) |
"Pretreatment with verapamil (1 or 10 microM), nifedipine (0." | 1.29 | The effects of phorbol 12,13-diacetate on responses of guinea-pig isolated trachea to methylxanthines, isoprenaline and ryanodine. ( Cortijo, J; Morcillo, EJ; Sanz, CM; Small, RC; Villagrasa, V, 1994) |
"Caffeine caused an increase in force only in < 20 Hz, but a decrease in 50 and 100 Hz." | 1.29 | The effects of theophylline and caffeine on the isolated rat diaphragm. ( Gölgeli, A; Ozesmi, C; Ozesmi, M, 1995) |
"Doxofylline also has a very low affinity for adenosine receptors inhibiting cAMP-phosphodiesterase as does theophylline." | 1.28 | Doxofylline differs from methylxanthines in its movement of cytosolic calcium. ( Cirillo, R; Franzone, JS; Reboani, MC, 1991) |
" Compound MV 8612 (8 and 16 microM) and MV 8610 (12 and 24 microM) caused a graded rightward displacement of BK dose-response curves in the isolated guinea pig trachea (dose ratio 2- to 4-fold)." | 1.28 | Effect of compounds from Mandevilla velutina on bradykinin-mediated contractile and relaxant responses of the isolated guinea pig trachea. ( Calixto, JB; Cruz, AB; Medeiros, YS; Yunes, RA, 1992) |
"Theophylline (0." | 1.28 | The effect of theophylline on hypoxic, hypercapnic hamster diaphragm muscle in vitro. ( Esau, SA, 1991) |
" The adenosine receptor antagonist 8-(p-sulphophenyl)theophylline (8-SPT, 50 microM) produced approximately 50 fold shifts of the dose-response curves to adenosine, AMP and AMPPCP, whereas those to ATP, MeSATP and substance P (SP) were unaffected." | 1.28 | A study of the purinoceptors mediating contraction in the rat colon. ( Bailey, SJ; Hourani, SM, 1990) |
" Dose-response curves for the effects of adenosine on K+ contractures indicated that at low doses adenosine decreases force and cytoplasmic ionized calcium but that at high concentrations (greater than 3." | 1.27 | Cellular Ca2+ monitored by aequorin in adenosine-mediated smooth muscle relaxation. ( Bradley, AB; Morgan, KG, 1985) |
" After steady-state subtherapeutic (less than 10 mg/l), therapeutic (10-20 mg/l), and toxic (greater than 20 mg/l) concentrations of theophylline, dose-response curves for dTC were determined and compared with controls that received no theophylline." | 1.27 | Concentration-dependent interaction of theophylline with d-tubocurarine. ( Basta, S; Fuke, N; Kim, CS; Martyn, J, 1987) |
"adenosine were significantly less than -1 unless the adenosine reuptake blocker dipyridamole (0." | 1.27 | Effects of caffeine and 8-phenyltheophylline on the actions of purines and opiates in the guinea-pig ileum. ( Ahlijanian, MK; Takemori, AE, 1986) |
"Theophylline is a competing antagonist of adenosine and a noncompeting antagonist of baclofen, clofelin and morphine." | 1.27 | [Theophylline-induced changes in the presynaptic effects of adenosine, baclofen, clofelin and morphine in the myenteric plexus of the guinea pig]. ( Kharin, NA; Komissarov, IV; Serdiuk, SE, 1987) |
" The dose-response curve for ATP-induced contraction was shifted to the right by theophylline." | 1.27 | Effect of apamin and theophylline on adenosine-5'-triphosphate-induced response of the guinea pig gallbladder. ( Ishikawa, Y; Takahashi, T; Yamamura, T, 1983) |
"Papaverine was shown to be the substance able to cause the biggest relaxation effect." | 1.27 | Relaxation of isolated corpus cavernosum induced by smooth-muscle relaxant drugs. A comparative study. ( Barbanti, G; Beneforti, P; Lapini, A; Turini, D, 1988) |
"Doxofylline is a new antibronchospastic drug, recently introduced in therapy, with pharmacological properties like theophylline, a potent adenosine receptor antagonist." | 1.27 | Doxofylline and theophylline are xanthines with partly different mechanisms of action in animals. ( Barone, D; Cirillo, R; Franzone, JS, 1988) |
"Theophylline and cAMP inhibit the X-ray contraction probably non-specifically." | 1.27 | Contractile reaction of isolated frog aorta after X-irradiation. ( Greimel, H; Michailov, MC; Prechter, I; Welscher, UE, 1983) |
"Theophylline was significantly less effective in antagonizing the bronchospasm elicited by maximally effective dose (100 micrograms/kg i." | 1.27 | Blockade by theophylline of capsaicin-induced motor effects in guinea-pig airways. ( Agostini, R; Ballati, L; Conti, S; Manzini, S, 1987) |
" The dose-response relationships of theophylline and enprofylline were studied on these preparations." | 1.27 | Potent bronchodilating effects of enprofylline and theophylline on contractions induced by egg albumin or by slow reacting substance (SRS). ( Andersson, RG; Hedman, SE, 1984) |
" The extent of overlap for the different calcium pools between the various agonists was determined by studying the dose-response relationships of these agents before and after pretreatment with another agonist, i." | 1.27 | Agonist interactions at the calcium pools in skinned and unskinned canine tracheal smooth muscle. ( Davis, C; Kannan, L; Kannan, MS; Ladenius, AR, 1987) |
"Carbachol-treated tracheal ring dimensions were compared with those of their matched theophylline-treated rings." | 1.27 | Quantitative measurement of smooth muscle shortening in isolated pig trachea. ( Hogg, JC; James, AL; Moreno, RH; Paré, PD, 1987) |
" Moreover, adenosine failed to alter the theophylline dose-response curve for diaphragmatic tension." | 1.27 | Comparative effects of theophylline and adenosine on respiratory skeletal and smooth muscle. ( Deal, EC; Kelsen, SG; Supinski, GS, 1986) |
"Theophylline was less potent in relaxing the potassium induced contraction." | 1.27 | Effects of theophylline on small human placental arteries in vitro. ( Nielsen-Kudsk, JE, 1985) |
" The aim of acute toxicity was, up to now, to determine LD50 level or eventually a minimal lethal dose." | 1.27 | Grip strength test and infrared thermometry as non-invasive methods to complement acute toxicity data in mice. ( Nordmann, H, 1985) |
"5." | 1.26 | Effects of some naturally-occurring purine ribosides on purinergic receptors in cardiac and smooth muscle. ( Fuhrman, FA; Fuhrman, GJ, 1982) |
" Cumulative dose-response curves with epinephrine and norepinephrine showed graded contraction." | 1.26 | Adrenergic receptors and sympathetic agents in isolated human pulmonary arteries. ( Boe, J; Simonsson, BG, 1980) |
"Propranolol has no effect on the response to any of the compounds." | 1.26 | Pharmacological studies with adenine, adenosine and some phosphorylated derivatives on guinea-pig tracheal muscle. ( Farmer, JB; Farrar, DG, 1976) |
" Dose-response curves for tracheal vasodilatation to the three drugs were all parallel together, and trapidil was about 2700 time less potent than isoproterenol and about 3 times more potent than theophylline on a weight basis in producing tracheal vasodilatation." | 1.26 | Effects of trapidil on musculature and vasculature of the dog trachea in situ. ( Maruyama, M; Satoh, K; Taira, N, 1981) |
"Pretreatment with theophylline enhanced the responses to dibutyryl cAMP and NaF." | 1.26 | A role of cyclic nucleotides in neuromuscular transmission. ( Dretchen, KL; Morgenroth, VH; Skirboll, LR; Standaert, FG, 1976) |
"5 Indomethacin treatment reversed the isoprenaline desensitization induced by chronic treatment (0." | 1.26 | Tolerance of guinea-pig airway muscle preparations to relaxant agonists induced by chronic exposure to isoprenaline in vivo. ( Brink, C, 1981) |
"Theophylline has no influence on the relaxing effect of 1 microng/ml fendiline." | 1.26 | The influence of the calcium antagonist fendiline on tone and motility of the guinea pig gut smooth muscle and the cAMP and cGMP concentrations of the isolated terminal ileum. ( Heim, F; Mitznegg, P; Sprügel, W, 1977) |
" The control log dose-response curve for epinephrine stimulation showed a slight decrease in the upper concentration range." | 1.25 | Rabbit testicular contractions: bimodal interaction of prostaglandin E1 with other agonists. ( Ellis, LC; Hargrove, JL; Seeley, RR, 1975) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 329 (70.75) | 18.7374 |
1990's | 90 (19.35) | 18.2507 |
2000's | 28 (6.02) | 29.6817 |
2010's | 18 (3.87) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Peet, NP | 1 |
Dickerson, GA | 1 |
Abdallah, AH | 1 |
Daly, JW | 2 |
Ukena, D | 1 |
Temple, DL | 1 |
Yevich, JP | 1 |
Catt, JD | 1 |
Owens, D | 1 |
Hanning, C | 1 |
Covington, RR | 1 |
Seidehamel, RJ | 1 |
Dungan, KW | 1 |
De Cunto, A | 1 |
Paviotti, G | 1 |
Bua, J | 1 |
Demarini, S | 1 |
Kim, WY | 1 |
Lim, CM | 1 |
Emami, B | 1 |
Shakeri, F | 1 |
Ghorani, V | 1 |
Boskabady, MH | 1 |
Patai, Z | 1 |
Guttman, A | 1 |
Mikus, EG | 1 |
Yu, TJ | 1 |
Liu, YC | 1 |
Chu, CM | 1 |
Hu, HC | 1 |
Kao, KC | 1 |
Bossé, Y | 1 |
Urbanova, A | 1 |
Kertys, M | 1 |
Simekova, M | 1 |
Mikolka, P | 1 |
Kosutova, P | 1 |
Mokra, D | 1 |
Mokry, J | 2 |
Yuzkat, N | 1 |
Kati, I | 1 |
Isik, Y | 1 |
Kavak, S | 1 |
Goktas, U | 1 |
Cengiz, N | 1 |
Ziganshin, AU | 4 |
Khairullin, AE | 1 |
Zobov, VV | 1 |
Ziganshina, LE | 2 |
Gabdrakhmanov, AI | 1 |
Ziganshin, BA | 2 |
Grishin, SN | 4 |
Nosalova, G | 1 |
Psarra, TA | 3 |
Batzias, GC | 3 |
Peeters, TL | 3 |
Koutsoviti-Papadopoulou, M | 3 |
Kamaliev, RR | 3 |
Burnstock, G | 8 |
Bozarov, A | 1 |
Wang, YZ | 1 |
Yu, JG | 1 |
Wunderlich, J | 1 |
Hassanain, HH | 1 |
Alhaj, M | 1 |
Cooke, HJ | 1 |
Grants, I | 1 |
Ren, T | 1 |
Christofi, FL | 2 |
Nilsson, KF | 1 |
Grishina, VA | 1 |
Glaumann, C | 1 |
Gustafsson, LE | 8 |
Kolnes, AJ | 1 |
Ingvaldsen, A | 1 |
Bolling, A | 1 |
Stuenaes, JT | 1 |
Kreft, M | 1 |
Zorec, R | 1 |
Shepherd, PR | 1 |
Jensen, J | 1 |
Fiege, M | 2 |
Weisshorn, R | 2 |
Kolodzie, K | 2 |
Wappler, F | 2 |
Gerbershagen, MU | 2 |
Leemans, J | 1 |
Kirschvink, N | 1 |
Gustin, P | 1 |
Teplov, AY | 1 |
Fredsted, A | 1 |
Gissel, H | 1 |
Ortenblad, N | 1 |
Clausen, T | 2 |
Tazzeo, T | 1 |
Bates, G | 1 |
Roman, HN | 1 |
Lauzon, AM | 1 |
Khasnis, MD | 1 |
Eto, M | 1 |
Janssen, LJ | 1 |
Karasu-Minareci, E | 1 |
Kaya, Y | 1 |
Belgin Yildirim, F | 1 |
Sakai, J | 1 |
Oike, M | 1 |
Hirakawa, M | 1 |
Ito, Y | 4 |
Kapilevich, LV | 1 |
Nosarev, AV | 1 |
Kovalev, IV | 1 |
D'yakova, EY | 1 |
Baskakov, MB | 1 |
DAVID, I | 1 |
KRUTA, V | 1 |
BRAVENY, P | 2 |
HLAVKOVA STEJSKALOVA, J | 1 |
HUSAKOVA, B | 1 |
Ise, S | 1 |
Nishimura, J | 1 |
Hirano, K | 1 |
Hara, N | 1 |
Kanaide, H | 1 |
Etlik, O | 1 |
Sakarya, ME | 1 |
Uzun, K | 1 |
Harman, M | 1 |
Temizoz, O | 1 |
Durmus, A | 1 |
Usta, C | 2 |
Sadan, G | 2 |
Tuncel, B | 1 |
Zefirov, AL | 1 |
Romanelli, L | 1 |
Palmery, M | 1 |
Tucci, P | 1 |
Amico, MC | 1 |
Morrone, LA | 1 |
Valeri, P | 1 |
Giglio, D | 2 |
Delbro, DS | 2 |
Tobin, G | 2 |
Kennedy, RH | 1 |
Owings, R | 1 |
Joseph, J | 1 |
Melchert, RB | 1 |
Hauer-Jensen, M | 1 |
Boerma, M | 1 |
Ghildyal, P | 1 |
Palani, D | 1 |
Manchanda, R | 1 |
Alexander, SP | 1 |
Yildiz, G | 1 |
Demiryürek, AT | 1 |
Gümüşel, B | 1 |
Lippton, H | 1 |
Aviado, DM | 1 |
Folle, LE | 1 |
Pisanty, J | 1 |
Bartelstone, HJ | 1 |
Nasmyth, PA | 1 |
Telford, JM | 1 |
Meester, WD | 1 |
Hardman, HF | 1 |
Fredholm, BB | 4 |
Fermum, R | 2 |
Möritz, KU | 2 |
Schäfer, U | 1 |
Leibelt, M | 1 |
Collier, HO | 2 |
Tucker, JF | 2 |
Gaion, RM | 2 |
Trento, M | 1 |
Bloch, R | 1 |
Decker, N | 1 |
Kostakopoulos, A | 1 |
Tofelde, U | 1 |
Paton, DM | 3 |
Svedmyr, N | 1 |
Svedmyr, K | 1 |
Standaert, FG | 6 |
Dretchen, KL | 7 |
Fuhrman, FA | 1 |
Fuhrman, GJ | 1 |
Middleton, E | 1 |
Sneddon, P | 2 |
Meldrum, LA | 1 |
Hopewell, PC | 1 |
Miller, RT | 1 |
Jenne, JW | 1 |
Huidobro-Toro, JP | 2 |
Yoshimura, K | 1 |
Weiss, EB | 1 |
Markowicz, J | 1 |
Barbero, L | 1 |
Ishikawa, Y | 3 |
Takahashi, T | 4 |
Yamamura, T | 4 |
Rohner, TJ | 1 |
Hannigan, J | 1 |
Okwuasaba, FK | 2 |
Cook, MA | 4 |
Jamieson, D | 1 |
Davis, P | 1 |
Dowdle, EB | 1 |
Maske, R | 1 |
Boe, J | 2 |
Simonsson, BG | 1 |
Webb, RC | 1 |
Bohr, DF | 1 |
Brink, C | 5 |
Fanò, G | 2 |
Della Torre, G | 1 |
Principato, GB | 1 |
Dolcini, BM | 1 |
Orlacchio, A | 1 |
Gustafsson, L | 1 |
Hedqvist, P | 1 |
Kishi, Y | 1 |
Numano, F | 1 |
Bianchi, CP | 1 |
Narayan, S | 1 |
Bauer, V | 1 |
Matusák, O | 1 |
Kuriyama, H | 3 |
Scappaticci, KA | 1 |
Ham, JA | 1 |
Sohn, YJ | 1 |
Miller, RD | 1 |
Polson, JB | 5 |
Krzanowski, JJ | 2 |
Szentivanyi, A | 3 |
Taylor, DA | 1 |
Wiese, S | 1 |
Faison, EP | 1 |
Yarbrough, GG | 1 |
Advenier, C | 5 |
Stone, TW | 1 |
Husted, S | 1 |
Sjögren, C | 3 |
Andersson, KE | 5 |
Michailov, MC | 1 |
Prechter, I | 1 |
Greimel, H | 1 |
Welscher, UE | 1 |
Mehta, AK | 1 |
Kulkarni, SK | 1 |
Brown, CM | 3 |
Collis, MG | 3 |
Hills, JM | 1 |
Hoyle, CH | 1 |
Kennedy, C | 1 |
Magnussen, H | 2 |
Scheidt-Mackes, M | 1 |
Elguindi, AS | 1 |
Stringfield, JT | 1 |
Bransome, ED | 2 |
Speir, WA | 4 |
Proctor, KG | 1 |
Satchell, D | 1 |
Smith, R | 1 |
Supinski, GS | 3 |
Deal, EC | 2 |
Kelsen, SG | 3 |
Hedman, SE | 1 |
Andersson, RG | 3 |
Staneva, D | 1 |
Chakurova, L | 1 |
Ivanova, N | 1 |
Spasov, V | 1 |
Raynova, L | 1 |
Bogoslovova, T | 1 |
Elliott, J | 2 |
Jhamandas, K | 2 |
Notman, H | 1 |
Sutak, M | 1 |
Thiele, K | 1 |
Jahn, U | 1 |
Geissmann, F | 1 |
Zirngibl, L | 1 |
Zuskin, E | 2 |
Duncan, PG | 2 |
Douglas, JS | 4 |
Santicioli, P | 1 |
Maggi, CA | 1 |
Meli, A | 1 |
Naughton, P | 1 |
Baer, HP | 3 |
Clanachan, AS | 2 |
Scott, GW | 1 |
Huddart, H | 2 |
Bayton, E | 1 |
Shanklin, J | 1 |
Ojewole, JA | 1 |
Ellis, EF | 2 |
Murciano, D | 3 |
Aubier, M | 9 |
Lecocguic, Y | 1 |
Pariente, R | 3 |
Barron, JT | 1 |
Bárány, M | 1 |
Bárány, K | 1 |
Storti, RV | 1 |
Morff, RJ | 1 |
Granger, HJ | 1 |
Auguet, M | 2 |
Clostre, F | 2 |
Flewellen, EH | 1 |
Nelson, TE | 1 |
Griffith, SG | 1 |
Meghji, P | 1 |
Moody, CJ | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effect of Transcutaneous Electrical Diaphragmatic Stimulation on Respiratory Muscle Strength, Diaphragm Thickness and Mechanical Ventilation Time in Critically Ill Elderly Patients[NCT04565002] | 44 participants (Anticipated) | Interventional | 2018-06-25 | Recruiting | |||
Effects of Continuous Mobility Training in Individuals With Prolonged Mechanical Ventilation : A Randomized Controlled Trial[NCT05688267] | 56 participants (Actual) | Interventional | 2023-02-01 | Completed | |||
Electroacupuncture to Assist Ventilator Weaning in Severe Stroke: a Randomized, Sham-controlled Pilot Study[NCT04816201] | 100 participants (Anticipated) | Interventional | 2021-04-01 | Recruiting | |||
Smell in COVID-19 and Efficacy of Nasal Theophylline 3[NCT05947643] | Phase 2 | 240 participants (Anticipated) | Interventional | 2022-11-22 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
23 reviews available for theophylline and Muscle Contraction
Article | Year |
---|---|
Ventilator-Induced Diaphragmatic Dysfunction: Diagnosis and Role of Pharmacological Agents.
Topics: Bronchodilator Agents; Diaphragm; Humans; Muscle Contraction; Muscular Diseases; Respiration, Artifi | 2017 |
Ventilator-Induced Diaphragmatic Dysfunction: Diagnosis and Role of Pharmacological Agents.
Topics: Bronchodilator Agents; Diaphragm; Humans; Muscle Contraction; Muscular Diseases; Respiration, Artifi | 2017 |
Ventilator-Induced Diaphragmatic Dysfunction: Diagnosis and Role of Pharmacological Agents.
Topics: Bronchodilator Agents; Diaphragm; Humans; Muscle Contraction; Muscular Diseases; Respiration, Artifi | 2017 |
Ventilator-Induced Diaphragmatic Dysfunction: Diagnosis and Role of Pharmacological Agents.
Topics: Bronchodilator Agents; Diaphragm; Humans; Muscle Contraction; Muscular Diseases; Respiration, Artifi | 2017 |
Ventilator-Induced Diaphragmatic Dysfunction: Diagnosis and Role of Pharmacological Agents.
Topics: Bronchodilator Agents; Diaphragm; Humans; Muscle Contraction; Muscular Diseases; Respiration, Artifi | 2017 |
Ventilator-Induced Diaphragmatic Dysfunction: Diagnosis and Role of Pharmacological Agents.
Topics: Bronchodilator Agents; Diaphragm; Humans; Muscle Contraction; Muscular Diseases; Respiration, Artifi | 2017 |
Ventilator-Induced Diaphragmatic Dysfunction: Diagnosis and Role of Pharmacological Agents.
Topics: Bronchodilator Agents; Diaphragm; Humans; Muscle Contraction; Muscular Diseases; Respiration, Artifi | 2017 |
Ventilator-Induced Diaphragmatic Dysfunction: Diagnosis and Role of Pharmacological Agents.
Topics: Bronchodilator Agents; Diaphragm; Humans; Muscle Contraction; Muscular Diseases; Respiration, Artifi | 2017 |
Ventilator-Induced Diaphragmatic Dysfunction: Diagnosis and Role of Pharmacological Agents.
Topics: Bronchodilator Agents; Diaphragm; Humans; Muscle Contraction; Muscular Diseases; Respiration, Artifi | 2017 |
Endocrine regulation of airway contractility is overlooked.
Topics: Adaptation, Physiological; Adiponectin; Androgens; Animals; Asthma; Bronchodilator Agents; Dehydroep | 2014 |
Effects of methylxanthines on skeletal muscle and on respiration.
Topics: Animals; Caffeine; Histamine Release; Muscle Contraction; Muscles; Respiration; Theobromine; Theophy | 1984 |
Sites and mechanisms of dependence in the myenteric plexus of guinea pig ileum.
Topics: Acetylcholine; Adenosine; Animals; Clonidine; Cyclic AMP; Guinea Pigs; Humans; Ileum; In Vitro Techn | 1984 |
In-vitro and in-vivo effects of theophylline and beta 2-adrenostimulants in combination.
Topics: Adrenergic beta-Agonists; Asthma; Bronchi; Drug Therapy, Combination; Humans; In Vitro Techniques; M | 1980 |
Cyclic nucleotides in neuromuscular transmission.
Topics: Acetylcholine; Action Potentials; Adenine Nucleotides; Animals; Azathioprine; Bucladesine; Cats; Cyc | 1981 |
Airway smooth muscle, asthma, and calcium ions.
Topics: Asthma; Asthma, Exercise-Induced; Autacoids; Binding Sites; Calcium; Calcium Channel Blockers; Calmo | 1984 |
Pathophysiology and management of severe asthma.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anesthesia, General; Anti-Infective Agents; Asthm | 1984 |
Theophylline use in asthma. Some current issues.
Topics: Adenosine; Adrenergic beta-Agonists; Animals; Asthma; Bronchi; Cardiac Output; Cyclic AMP; Drug Ther | 1984 |
[Theophylline: mechanism of action, pharmacokinetics and metabolism].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adult; Calcium; Child; Cyclic AMP; Drug Interactions | 1981 |
[Effect of theophylline on the contractility of the diaphragm].
Topics: Diaphragm; Humans; Lung Diseases, Obstructive; Muscle Contraction; Pulmonary Emphysema; Theophylline | 1983 |
Review of the clinical efficacy of theophylline in the treatment of chronic obstructive pulmonary disease.
Topics: Animals; Cardiovascular System; Dyspnea; Humans; Lung Diseases, Obstructive; Mucous Membrane; Muscle | 1993 |
Theophylline and the respiratory muscles: where are we?
Topics: Animals; Humans; Muscle Contraction; Respiratory Muscles; Theophylline | 1989 |
Respiratory muscle pharmacotherapy.
Topics: Digitalis Glycosides; Humans; Muscle Contraction; Respiratory Insufficiency; Respiratory System; Ter | 1989 |
Theophylline: an overview.
Topics: Drug Interactions; Humans; Muscle Contraction; Theophylline | 1988 |
Pharmacotherapy of respiratory muscles.
Topics: Animals; Caffeine; Humans; Muscle Contraction; Respiratory Insufficiency; Respiratory Muscles; Stimu | 1988 |
Aminophylline and the respiratory muscles: an alternative view.
Topics: Aminophylline; Humans; Muscle Contraction; Respiratory Insufficiency; Respiratory Muscles; Theophyll | 1988 |
Effect of theophylline on diaphragmatic muscle function.
Topics: Aminophylline; Animals; Diaphragm; Electromyography; Humans; Lung Diseases, Obstructive; Muscle Cont | 1987 |
Effect of theophylline on diaphragmatic and other skeletal muscle function.
Topics: Animals; Diaphragm; Humans; In Vitro Techniques; Lung Diseases, Obstructive; Muscle Contraction; Mus | 1986 |
The positive inotropic effect of cyclic AMP.
Topics: Aminophylline; Animals; Butyrates; Caffeine; Cyclic AMP; Epinephrine; Glucagon; Guinea Pigs; Heart; | 1972 |
Cyclic GMP and gastric acid secretion.
Topics: Animals; Cyclic AMP; Cyclic GMP; Depression, Chemical; Gallbladder; Gastric Juice; Glycyrrhiza; Inte | 1974 |
Role of cyclic nucleotides in the nervous system.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Brain; Cyclic AMP; Cyclic GMP; Diaphragm; Humans; Muscle | 1974 |
Body-temperature and responses to drugs.
Topics: Acetylcholine; Anesthetics; Animals; Body Temperature; Body Temperature Regulation; Cats; Chlorproma | 1969 |
7 trials available for theophylline and Muscle Contraction
Article | Year |
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Effects of theophylline on diaphragmatic strength and fatigue in patients with chronic obstructive pulmonary disease.
Topics: Diaphragm; Humans; Lung Diseases, Obstructive; Middle Aged; Muscle Contraction; Respiration; Theophy | 1984 |
Verapamil causes decreased diaphragm endurance but no decrease of nocturnal O(2) saturation in patients with chronic obstructive pulmonary disease.
Topics: Aged; Blood Gas Analysis; Calcium Channel Blockers; Circadian Rhythm; Cross-Over Studies; Diaphragm; | 2000 |
The effect of theophylline on respiratory muscle contractility and fatigue.
Topics: Animals; Diaphragm; Dogs; Double-Blind Method; Fatigue; Guinea Pigs; Humans; Lung Diseases, Obstruct | 1990 |
Theophylline and diaphragmatic contractility. Investigation of a dose-response relationship.
Topics: Clinical Trials as Topic; Diaphragm; Dose-Response Relationship, Drug; Double-Blind Method; Humans; | 1988 |
In vivo effects of theophylline on diaphragm, bicep, and quadricep strength and fatigability.
Topics: Adult; Arm; Diaphragm; Humans; Isometric Contraction; Male; Muscle Contraction; Placebos; Pressure; | 1988 |
Effects of theophylline and enprofylline on diaphragmatic contractility.
Topics: Adult; Bronchodilator Agents; Diaphragm; Humans; Kinetics; Male; Muscle Contraction; Muscles; Theoph | 1987 |
Effect of aminophylline on fatigue of the sternomastoid muscle in man.
Topics: Adult; Aminophylline; Electric Stimulation; Female; Humans; Male; Muscle Contraction; Muscles; Neck | 1986 |
435 other studies available for theophylline and Muscle Contraction
Article | Year |
---|---|
Benzo[1,2-c:5,4-c']dipyrazoles: non-xanthine adenosine antagonists.
Topics: Adenosine; Animals; Bronchi; Guinea Pigs; Humans; Muscle Contraction; Pyrazoles; Rats; Receptors, Pu | 1988 |
Substituted 6,7-dihydroimidazo[1,2-a]purin-9(4H)-ones.
Topics: Animals; Bronchial Spasm; Bronchodilator Agents; Chemical Phenomena; Chemistry; Female; Guinea Pigs; | 1980 |
Theophylline increases diaphragmatic contractility in mechanically ventilated newborns.
Topics: Diaphragm; Humans; Infant, Newborn; Muscle Contraction; Theophylline | 2017 |
Relaxant effect of Curcuma longa on rat tracheal smooth muscle and its possible mechanisms.
Topics: Animals; Bronchodilator Agents; Curcuma; Dose-Response Relationship, Drug; Ethanol; Male; Methacholi | 2017 |
Assessment of the Airway Smooth Muscle Relaxant Effect of Drotaverine.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smoo | 2018 |
Effects of theophylline therapy on respiratory muscle strength in patients with prolonged mechanical ventilation: A retrospective cohort study.
Topics: Aged; Aged, 80 and over; Diaphragm; Humans; Middle Aged; Muscle Contraction; Muscle Strength; Respir | 2019 |
Bronchodilator and Anti-Inflammatory Action of Theophylline in a Model of Ovalbumin-Induced Allergic Inflammation.
Topics: Airway Resistance; Animals; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Bronchoconstriction | 2016 |
Effects of Theophylline with Methylprednisolone Combination Therapy on Biomechanics and Histopathology in Diaphragm Muscles of Rats.
Topics: Animals; Biomechanical Phenomena; Diaphragm; Drug Synergism; Drug Therapy, Combination; Methylpredni | 2016 |
Effects of ATP and adenosine on contraction amplitude of rat soleus muscle at different temperatures.
Topics: Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Carbachol; Cholinergic Agonists; E | 2017 |
In vitro reactivity of urinary bladder smooth muscle in rabbits influenced by xanthine derivatives.
Topics: Acetylcholine; Animals; Caffeine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Rabbits; | 2008 |
Relaxing and contracting effects of theophylline's metabolites on the rabbit upper gastrointestinal tract.
Topics: Animals; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Muscle Contraction; Mu | 2008 |
Interaction of hydrocortisone with ATP and adenosine on nerve-mediated contractions of frog skeletal muscle.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Drug Interactions; Ele | 2009 |
The gastrointestinal effects that may follow the administration of theophylline reflect the pharmacodynamic profiles of both the parent drug and its metabolites.
Topics: Acetylcholine; Animals; Bronchodilator Agents; Dose-Response Relationship, Drug; Female; Gastrointes | 2010 |
Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine.
Topics: Adenosine; Animals; Chlorides; Cimetidine; Colon; Dihydropyridines; Dimaprit; Dose-Response Relation | 2009 |
Estimation of endogenous adenosine activity at adenosine receptors in guinea-pig ileum using a new pharmacological method.
Topics: 2-Chloroadenosine; Adenosine; Animals; Dilazep; Dose-Response Relationship, Drug; Guinea Pigs; Ileum | 2010 |
Caffeine and theophylline block insulin-stimulated glucose uptake and PKB phosphorylation in rat skeletal muscles.
Topics: Animals; Caffeine; Dantrolene; Dose-Response Relationship, Drug; Electric Stimulation; Glucose; Gluc | 2010 |
Effects of theophylline on anesthetized malignant hyperthermia-susceptible pigs.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Calcium; Disease Models, Animal; D | 2011 |
A comparison of in vitro relaxant responses to ipratropium bromide, β-adrenoceptor agonists and theophylline in feline bronchial smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Bronchi; Bronchodilator Agents; Cats; Cholinergic Antagonists; Do | 2012 |
Opposite effect of ATP on contraction force of tonic and phasic skeletal muscles in frogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Muscle Contraction; Muscle Fibers, Skeletal; Mu | 2011 |
Effects of β₂-agonists on force during and following anoxia in rat extensor digitorum longus muscle.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Bucladesine; Deoxyglucose; Electric Stimula | 2012 |
Caffeine relaxes smooth muscle through actin depolymerization.
Topics: Actins; Animals; Biopolymers; Caffeine; Cattle; Enzyme Assays; Humans; In Vitro Techniques; Indoles; | 2012 |
The achilles heel in melatonin: asthma.
Topics: Acetylcholine; Animals; Asthma; Circadian Rhythm; Dose-Response Relationship, Drug; Injections, Intr | 2012 |
Theophylline and cAMP inhibit lysophosphatidic acid-induced hyperresponsiveness of bovine tracheal smooth muscle cells.
Topics: Actins; Animals; Bronchial Hyperreactivity; Bronchodilator Agents; Calcium; Cattle; Cells, Cultured; | 2003 |
Role of cyclic nucleotides in regulation of pulmonary artery tone in rabbits.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Cyclic GMP; Dipyridamole; In Vitro Techniques; Iso | 2003 |
[Contractile action of methylxanthines].
Topics: Caffeine; Humans; Muscle Contraction; Theobromine; Theophylline; Xanthines | 1957 |
[RESTORATION OF MYOCARDIAL CONTRACTILITY AND INOTROPIC EFFECTS (OUABAIN, QUINIDINE, TYRAMINE, THEOPHYLLINE AND ACETYLCHOLINE) IN GUINEA PIGS AND RATS].
Topics: Acetylcholine; Guinea Pigs; Muscle Contraction; Myocardium; Ouabain; Quinidine; Rats; Research; Stro | 1963 |
Theophylline attenuates Ca2+ sensitivity and modulates BK channels in porcine tracheal smooth muscle.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; In Vitro Techniques; Large-Conductance Calcium-A | 2003 |
[Theophylline induces contractures in porcine skeletal muscle preparations with the disposition to malignant hyperthermia].
Topics: Animals; Calcium; Electric Stimulation; In Vitro Techniques; Malignant Hyperthermia; Muscle Contract | 2004 |
Demonstrating the effect of theophylline treatment on diaphragmatic movement in chronic obstructive pulmonary disease patients by MR-fluoroscopy.
Topics: Adult; Aged; Diaphragm; Exhalation; Female; Forced Expiratory Volume; Humans; Inhalation; Magnetic R | 2004 |
The effect of the indomethacin on phosphodiesterase inhibitors mediated responses in isolated trachea preparations.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Guinea Pigs; Histamine; In Vitro Techniques; Indom | 2004 |
The influence of hypothermia on P2 receptor-mediated responses of frog skeletal muscle.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Dose-Response R | 2005 |
Involvement of the cannabinoid CB1 receptor in the opioid inhibition of the response to cholecystokinin and acute withdrawal response.
Topics: Acute Disease; Adenosine A1 Receptor Antagonists; Analgesics, Opioid; Animals; Benzoxazines; Cholecy | 2005 |
Postjunctional modulation by muscarinic M2 receptors of responses to electrical field stimulation of rat detrusor muscle preparations.
Topics: Animals; Diamines; Electric Stimulation; In Vitro Techniques; Muscarinic Antagonists; Muscle Contrac | 2005 |
Acute dilatory and negative inotropic effects of homocysteine are inhibited by an adenosine blocker.
Topics: Acetylcholine; Adenosine; Animals; Anti-Arrhythmia Agents; Atropine; Calcium Channel Blockers; Coron | 2006 |
Post- and prejunctional consequences of ecto-ATPase inhibition: electrical and contractile studies in guinea-pig vas deferens.
Topics: Action Potentials; Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Electrophy | 2006 |
Flavonoids as antagonists at A1 adenosine receptors.
Topics: Adenosine A1 Receptor Antagonists; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Elect | 2006 |
Ischemic preconditioning modulates ischemia-reperfusion injury in the rat lung: role of adenosine receptors.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Ischemic Preconditioning; Lung; Male; Malondi | 2007 |
Theophylline and its metabolites produce a stimulating cholinergic effect on the small intestine and a nonadrenergic noncholinergic relaxing effect on the colon: a comparative study in the rabbit intestine.
Topics: Animals; Bronchodilator Agents; Colon; Dose-Response Relationship, Drug; Female; Intestine, Small; M | 2007 |
The cardiopulmonary effects of a quinazoline (MJ 1988): cardiac stimulant, pulmonary vasodilator and bronchodilator.
Topics: Aminophylline; Animals; Arrhythmias, Cardiac; Blood Flow Velocity; Bronchi; Dogs; Heart; Muscle Cont | 1967 |
The significance of adenosine cyclic 3',5'-monophosphate for the contraction of smooth muscle.
Topics: Adenine Nucleotides; Animals; Aorta; Blood Vessels; Cats; Decerebrate State; Dogs; Electrophysiology | 1967 |
Blockade of the positive inotropic actions of epinephrine and theophylline by acetylcholine.
Topics: Acetylcholine; Adenine Nucleotides; Animals; Atropine; Calcium; Drug Antagonism; Electric Stimulatio | 1967 |
[Adenosine-3',5'-monophosphate content and muscle tension in isolated coronary arteries under the effect of lanthanum ions].
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cattle; Coronary Vessels; Cyclic AMP; In Vitro Techniques; Iso | 1984 |
The role of adrenergic, purinergic and opiate receptors in the control of prostacyclin-induced contraction in the guinea-pig ileum.
Topics: Animals; Epoprostenol; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contr | 1984 |
Effects of theophylline and isoproterenol on the activity on the isolated guinea pig ureter.
Topics: Animals; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contracti | 1984 |
Adenosine antagonism and related effects of theophylline derivatives in guinea pig ileum longitudinal muscle.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Atropine; Choline; Electric Stimulation; Guine | 1984 |
[Dissociation of the action of isoprenaline on muscle tension and adenosine-3',5'-monophosphate synthesis in isolated coronary arteries under the effect of diisopropylfluorophosphate].
Topics: Adenylyl Cyclases; Animals; Atropine; Cattle; Coronary Vessels; Cyclic AMP; In Vitro Techniques; Iso | 1984 |
Presynaptic inhibition of neurotransmission in rat vas deferens by 2-(p-methoxyphenyl) adenosine, ethyl adenosine-5'-carboxylate and N-cyclopropyl adenosine-5'-carboxamide.
Topics: Adenosine; Animals; Dipyridamole; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; | 1980 |
Studies on modulation of transmitter release and effector responsiveness in autonomic cholinergic neurotransmission.
Topics: Acetylcholine; Adenosine; Animals; Cattle; Cholinergic Fibers; Electric Stimulation; Female; Guinea | 1980 |
Effects of some naturally-occurring purine ribosides on purinergic receptors in cardiac and smooth muscle.
Topics: Adenosine; Animals; Guanosine; Guinea Pigs; Heart; In Vitro Techniques; Invertebrates; Muscle Contra | 1982 |
Control of transmitter release in guinea-pig vas deferens by prejunctional P1-purinoceptors.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Triphosphate; Animals; Dipyridamole; Electric Stimu | 1984 |
Pharmacological characterization of the inhibitory effects of neurotensin on the rabbit ileum myenteric plexus preparation.
Topics: Adenosine Triphosphate; Animals; Apamin; Dynorphins; Epinephrine; In Vitro Techniques; Male; Muscle | 1983 |
Effect of calcium antagonists in experimental asthma.
Topics: Anaphylaxis; Animals; Asthma; Calcium Channel Blockers; Depression, Chemical; Disease Models, Animal | 1982 |
[Action of adenosine 5'-triphosphate and effects of various purinergic receptor blocking agents on the movements of an isolated guinea pig gallbladder].
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Apamin; Atropine; Female; Gallbladder; | 1983 |
Effect of norepinephrine and isoproterenol on in vitro detrusor muscle contractility and cyclic AMP content.
Topics: Animals; Cyclic AMP; Dogs; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Mus | 1980 |
The effect of theophylline and other methylxanthines on presynaptic inhibition of the longitudinal smooth muscle of the guinea pig ileum induced by purine nucleotides.
Topics: Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Mu | 1980 |
Inhibition of nerve-mediated contractions in isolated guinea-pig ileum by 1-methylisoguanosine, a novel purine from a sponge.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Guanosine; Guinea Pigs; | 1980 |
The effects of calcium concentration on the inhibition of cholinergic neurotransmission in the myenteric plexus of guinea-pig ileum by adenine nucleotides.
Topics: Adenine Nucleotides; Animals; Calcium; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques | 1980 |
Adrenergic receptors and sympathetic agents in isolated human pulmonary arteries.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; In Vitro Techniques; Ind | 1980 |
Relaxation of vascular smooth muscle by isoproterenol, dibutyryl-cyclic AMP and theophylline.
Topics: Animals; Arteries; Bucladesine; Cats; Dogs; Female; In Vitro Techniques; Isoproterenol; Male; Muscle | 1981 |
Tolerance of guinea-pig airway muscle preparations to relaxant agonists induced by chronic exposure to isoprenaline in vivo.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Female; Guinea Pigs; Histamine; In Vitro | 1981 |
Effect of theophylline and imidazole on cyclic AMP and cyclic GMP levels in active sartorius muscle of Rana esculenta.
Topics: Animals; Cyclic AMP; Cyclic GMP; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscles; Rana | 1981 |
Theophylline interferes with the modulatory role of endogenous adenosine on cholinergic neurotransmission in guinea pig ileum.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cholin | 1981 |
A study of the mechanism of estrogen as an antiatherosclerotic: the inhibitory effect of estrogen on A23187-induced contraction of the aortic wall.
Topics: Animals; Anti-Bacterial Agents; Aorta; Bucladesine; Calcimycin; Cyclic AMP; Cyclic GMP; Estradiol; M | 1982 |
Possible role of the transverse tubules in accumulating calcium released from the terminal cisternae by stimulation and drugs.
Topics: Animals; Anura; Caffeine; Calcium; Electric Stimulation; In Vitro Techniques; Ion Channels; Muscle C | 1982 |
Non-cholinergic, non-adrenergic responses to nerve stimulation of different regions of the guinea-pig small intestine.
Topics: Adenosine Triphosphate; Animals; Atropine; Electric Stimulation; Guanethidine; Guinea Pigs; Ileum; I | 1982 |
Effects of furosemide on the neuromuscular junction.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cats; Dose-Response Relationship, Drug; Furosemide; Ma | 1982 |
Inhibition of a high affinity cyclic AMP phosphodiesterase and relaxation of canine tracheal smooth muscle.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Caffeine; Cyclic AMP; Dogs; Etazolate; Female; Male; M | 1982 |
Pharmacological characterization of purinergic receptors in the rat vas deferens.
Topics: Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Muscle Contractio | 1983 |
Purine receptors in the rat anococcygeus muscle.
Topics: Adenosine; Adenosine Triphosphate; Animals; Guanethidine; In Vitro Techniques; Male; Muscle Contract | 1983 |
Direct effects of adenosine and adenine nucleotides on isolated human urinary bladder and their influence on electrically induced contractions.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adult; Aged; Atropine; Dipyri | 1983 |
Contractile reaction of isolated frog aorta after X-irradiation.
Topics: Animals; Aorta; Atropine; Cyclic AMP; Indomethacin; Methysergide; Muscle Contraction; Muscle, Smooth | 1983 |
Evidence for the presence of P1- and P2-purinoceptors in rat caecum.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Caffeine; Cecum; Cyclic AMP; Female; | 1983 |
Adenosine A1 receptor mediated inhibition of nerve stimulation-induced contractions of the rabbit portal vein.
Topics: Adenosine; Animals; Cocaine; Dextroamphetamine; Dipyridamole; Electric Stimulation; Female; In Vitro | 1983 |
Effect of apamin and theophylline on adenosine-5'-triphosphate-induced response of the guinea pig gallbladder.
Topics: Adenosine Triphosphate; Animals; Apamin; Bee Venoms; Dose-Response Relationship, Drug; Female; Gallb | 1983 |
Adenosine relaxes the aorta by interacting with an A2 receptor and an intracellular site.
Topics: Adenosine; Animals; Aorta; Dipyridamole; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques | 1983 |
Evidence that the P1-purinoceptor in the guinea-pig taenia coli is an A2-subtype.
Topics: Adenosine; Animals; Colon; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Cont | 1984 |
Evidence for an inhibitory prejunctional P1-purinoceptor in the rat portal vein with characteristics of the A2 rather than of the A1 subtype.
Topics: Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smo | 1984 |
Effect of CO2 induced pH changes on the response of isolated guinea pig tracheas to theophylline.
Topics: Animals; Carbon Dioxide; Guinea Pigs; Histamine; Hydrogen-Ion Concentration; In Vitro Techniques; Ma | 1983 |
Reduction of contraction-induced arteriolar vasodilation by adenosine deaminase or theophylline.
Topics: Adenosine Deaminase; Animals; Arterioles; Cheek; Cricetinae; Electric Stimulation; Male; Microcircul | 1984 |
Adenosine causes contractions in spiral strips and relaxations in transverse strips of guinea-pig trachea: studies on mechanism of action.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; | 1984 |
The effects of caffeine and theophylline on diaphragm contractility.
Topics: Adult; Caffeine; Catheterization; Diaphragm; Electromyography; Esophagus; Humans; Male; Muscle Contr | 1984 |
Potent bronchodilating effects of enprofylline and theophylline on contractions induced by egg albumin or by slow reacting substance (SRS).
Topics: Adenosine Deaminase; Albumins; Animals; Bronchi; Female; Guinea Pigs; Male; Muscle Contraction; Musc | 1984 |
Pharmacological and toxicological studies of an original xanthine derivative with bronchodilatating activity.
Topics: Acetylcholine; Aminophylline; Animals; Bronchi; Bronchodilator Agents; Cats; Diuresis; Guinea Pigs; | 1984 |
Antagonism of enkephalin action on acetylcholine release by methylxanthines: lack of a purine link.
Topics: Acetylcholine; Adenosine; Animals; Caffeine; Cerebral Cortex; Enkephalins; Guinea Pigs; In Vitro Tec | 1983 |
[New biologically active theophylline derivatives. Synthesis and pharmacologic properties of flufylline and fluprofylline].
Topics: 5-Hydroxytryptophan; Animals; Anti-Inflammatory Agents; Blood Pressure; Bronchi; Chemical Phenomena; | 1984 |
The pharmacological characterization of aqueous extracts of vegetable dusts.
Topics: Animals; Caffeine; Coffee; Female; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle Rela | 1983 |
The effects of clonidine on electrically-induced contractions of rat detrusor strips in vitro.
Topics: Acetylcholine; Animals; Atropine; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Muscle | 1983 |
Adenosine and ATP effects on isolated guinea pig gallbladder.
Topics: Adenosine; Adenosine Triphosphate; Animals; Culture Techniques; Drug Interactions; Gallbladder; Guan | 1983 |
Influence of some common methylxanthines on contractile responses and calcium mobilization of ileal, vas deferens and bladder smooth muscle.
Topics: Animals; Caffeine; Calcium; Ileum; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Stra | 1983 |
Non-cholinergic, non-adrenergic responses of the rainbow lizard isolated rectum to transmural electrical stimulation.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Female; In Vitro Techniques; Lizards; Male; M | 1983 |
Novel form of drug-dependence--on adenosine in guinea pig ileum.
Topics: Adenosine; Animals; Caffeine; Guinea Pigs; Humans; Ileum; Morphine Derivatives; Muscle Contraction; | 1983 |
Inhibition of exercise-induced asthma by theophylline.
Topics: Asthma; Asthma, Exercise-Induced; Drug Administration Schedule; Humans; Lung; Muscle Contraction; Th | 1984 |
Reversible phosphorylation and dephosphorylation of the 20,000-dalton light chain of myosin during the contraction-relaxation-contraction cycle of arterial smooth muscle.
Topics: Animals; Calcium; Carotid Arteries; Chlorpromazine; Egtazic Acid; Muscle Contraction; Muscle Relaxat | 1980 |
Responses of the pulmonary artery to asthma-drugs.
Topics: Asthma; Bronchi; Humans; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Mus | 1983 |
Pharmacological characterisation of extracts of coffee dusts.
Topics: Animals; Coffee; Dose-Response Relationship, Drug; Dust; Female; Guinea Pigs; Histamine; In Vitro Te | 1983 |
Contribution of adenosine to arteriolar autoregulation in striated muscle.
Topics: Adenosine; Animals; Arteries; Arterioles; Dose-Response Relationship, Drug; Male; Muscle Contraction | 1983 |
Effects of an extract of Ginkgo biloba and diverse substances on the phasic and tonic components of the contraction of an isolated rabbit aorta.
Topics: Animals; Calcium; Gallopamil; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascula | 1983 |
Is theophylline, aminophylline, or caffeine (methylxanthines) contraindicated in malignant hyperthermia susceptible patients?
Topics: Adolescent; Adult; Aminophylline; Caffeine; Child; Halothane; Humans; In Vitro Techniques; Male; Mal | 1983 |
Evidence in support of the P1/P2 purinoceptor hypothesis in the guinea-pig taenia coli.
Topics: Adenine Nucleotides; Adenosine; Animals; Apamin; Colon; Dose-Response Relationship, Drug; Female; Gu | 1981 |
8-phenyltheophylline: a potent P1-purinoceptor antagonist.
Topics: Adenosine; Animals; Basilar Artery; Female; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Ma | 1981 |
Low-frequency fatigue in isolated skeletal muscles and the effects of methylxanthines.
Topics: Animals; Caffeine; Female; Mice; Muscle Contraction; Muscles; Theophylline; Xanthines | 1982 |
Mode of action of ATP on propulsive activity in rabbit colon.
Topics: Adenosine Triphosphate; Animals; Colon; Electric Stimulation; Female; Gastrointestinal Motility; In | 1982 |
Aminophylline.
Topics: Aminophylline; Diaphragm; Humans; Muscle Contraction; Theophylline | 1982 |
Influence of tracheal contraction on relaxant effects in vitro of theophylline and isoprenaline.
Topics: Airway Resistance; Animals; Carbachol; Drug Interactions; Female; Guinea Pigs; Hydrogen-Ion Concentr | 1981 |
Methylxanthines antagonize adenosine but not morphine inhibition in guinea pig ileum.
Topics: Adenosine; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, S | 1981 |
Quantitization of Ca spike frequency in a single sucrose gap and mechanical relaxation induced by Ca antagonists, isoproterenol and papaverine.
Topics: Action Potentials; Calcium; Calcium Channel Blockers; Humans; In Vitro Techniques; Isoproterenol; Ma | 1981 |
Effects of trapidil on musculature and vasculature of the dog trachea in situ.
Topics: Animals; Blood Pressure; Dogs; Female; Hemodynamics; Isoproterenol; Male; Muscle Contraction; Pyrimi | 1981 |
Adenosine antagonism, a less desirable characteristic of xanthine asthma drugs?
Topics: Adenosine; Animals; Asthma; Guinea Pigs; Humans; In Vitro Techniques; Male; Mice; Motor Activity; Mu | 1981 |
Action of coenzyme A on adenine derivative receptors in isolated tissues.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coenzyme A; Dose-Respons | 1980 |
Role of adenosine in exercise vasodilation in dog gracilis muscle.
Topics: Adenosine; Animals; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Muscle Contraction; Muscle | 1980 |
Inhibition of fundic strips from guinea-pig stomach: the effect of theophylline on responses to adenosine, ATP and intramural nerve stimulation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Drug Interactions; Electric Stimulation; Female; Guinea | 1980 |
[Polarization of nerve terminals induced by direct electrical stimulation of frog skeletal muscle].
Topics: Action Potentials; Animals; Anura; Electric Stimulation; Muscle Contraction; Neuromuscular Junction; | 1980 |
Reactivity of isolated canine cerebral arteries to adenine nucleotides and adenosine.
Topics: Adenine Nucleotides; Adenosine; Animals; Cerebral Arteries; Dogs; Female; In Vitro Techniques; Male; | 1980 |
Characterization of the methylxanthine-induced propagated wave phenomenon in striated muscle.
Topics: Animals; Caffeine; Chick Embryo; Halothane; Histocytochemistry; Muscle Contraction; Muscles; Quinine | 1980 |
Mechanism of the vascular action of parathyroid hypertensive factor.
Topics: Animals; Biological Factors; Blood Pressure; Calcium; Calcium Channels; Cells, Cultured; Dose-Respon | 1994 |
Smooth muscle contractility in prostatic hyperplasia: role of cyclic adenosine monophosphate.
Topics: Bucladesine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Male; Milrinone; Muscl | 1994 |
Inhibition by cromakalim, pinacidil, terbutaline, theophylline and verapamil of non-cholinergic nerve-mediated contractions of guinea-pig isolated bronchi.
Topics: Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Cromakalim; Dose-Response Relationship, Drug; | 1994 |
Pharmacological analysis of the interaction between purinoceptor agonists and antagonists in the guinea-pig taenia caecum.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cecum; Dipyridamole; Do | 1995 |
Synthetic studies on condensed-azole derivatives. I. Synthesis and anti-asthmatic activities of omega-substituted alkylthioimidazo[1,2-b]pyridazines.
Topics: Animals; Anti-Asthmatic Agents; Bronchodilator Agents; Enzyme Inhibitors; Guinea Pigs; In Vitro Tech | 1995 |
Synthetic studies on condensed-azole derivatives. III. Synthesis and anti-asthmatic activities of C-substituted alkyl side chain derivatives of omega-sulfamoylalkylthioimidazo[1,2-b]pyridazines and related compounds.
Topics: Animals; Anti-Asthmatic Agents; Bronchodilator Agents; Enzyme Inhibitors; Guinea Pigs; In Vitro Tech | 1995 |
Furosemide inhibits bradykinin-induced contraction of human bronchi: role of thromboxane A2 receptor antagonism.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Animals; Binding, C | 1995 |
The purinoceptors of the guinea-pig isolated taenia caeci.
Topics: Adenosine; Animals; Cecum; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscl | 1995 |
Evidence for a protective effect of theophylline and caffeine on cyclosporine-induced contractions in two in vitro glomerular models.
Topics: Animals; Caffeine; Cyclosporine; Dose-Response Relationship, Drug; Glomerular Mesangium; In Vitro Te | 1995 |
Adenosine inhibits efferent function of extrinsic capsaicin-sensitive sensory nerves in the enteric nervous system.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Adenosine; Animals; Capsaicin; Electric Stimulation; Ele | 1993 |
Theophylline increases oxygen consumption during inspiratory resistive loading.
Topics: Animals; Diaphragm; Dogs; Lung Diseases; Muscle Contraction; Oxygen Consumption; Regional Blood Flow | 1995 |
Further investigations into adenosine A1 receptor-mediated contraction in rat colonic muscularis mucosae and its augmentation by certain alkylxanthine antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colon; Cyclooxygenase Inhibitors; In Vitro Te | 1995 |
Endogenous adenosine mediates coronary vasodilation during exercise after K(ATP)+ channel blockade.
Topics: Adenosine; Animals; Coronary Circulation; Diastole; Dogs; Glyburide; Guanidines; Hemodynamics; Hyper | 1995 |
The role of cyclic AMP and phosphodiesterase activity in the mechanism of action of tetramethylpyrazine on human and dog cardiac and dog coronary arterial tissues.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Action Potentials; Animals; Coronary Vessels; Cyclic AMP; Dogs; | 1993 |
Effects of alkylxanthines on contractility of diaphragm fibres isolated from normal and sensitized guinea-pigs.
Topics: Adenosine; Animals; Bronchodilator Agents; Caffeine; Calcium; Culture Media; Dantrolene; Diaphragm; | 1993 |
The effects of phorbol 12,13-diacetate on responses of guinea-pig isolated trachea to methylxanthines, isoprenaline and ryanodine.
Topics: Animals; Caffeine; Calcium Chloride; Cold Temperature; Drug Interactions; Female; Guinea Pigs; Hista | 1994 |
Subtypes of purinoceptors in rat and dog urinary bladder smooth muscles.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dogs; Female; In V | 1994 |
Differential effects of suramin on P2-purinoceptors mediating contraction of the guinea-pig vas deferens and urinary bladder.
Topics: Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Magnesium; Male; Muscle Contracti | 1994 |
ATP induced-relaxation in the mouse bladder smooth muscle.
Topics: Adenosine Triphosphate; Animals; Calcium; Cytosol; Electric Stimulation; Fura-2; In Vitro Techniques | 1993 |
Indirect excitatory actions of histamine on isolated chicken oesophagus.
Topics: Animals; Atropine; Chickens; Esophagus; Female; Histamine; In Vitro Techniques; Male; Muscle Contrac | 1993 |
Adenosine induces contractions in suncus ileum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atropine | 1993 |
Inotropic effects of theophylline on foreshortened canine diaphragm.
Topics: Analysis of Variance; Animals; Diaphragm; Dogs; Dose-Response Relationship, Drug; In Vitro Technique | 1994 |
Pharmacological actions of the coenzymes NAD(H) and NADP(H) on the rat anococcygeus muscle.
Topics: Adenosine; Animals; Arginine; Electric Stimulation; Male; Muscle Contraction; Muscle Relaxation; NAD | 1994 |
Twitch potentiating effects of theophylline on rat diaphragm are enhanced by foreshortening.
Topics: Animals; Diaphragm; Lung Diseases, Obstructive; Male; Muscle Contraction; Rats; Rats, Wistar; Respir | 1994 |
Ryanodine and theophylline-induced depletion of energy stores in amphibian muscle.
Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Drug Interactions; Energy Metabol | 1994 |
Evidence for decrease in myofilament responsiveness to Ca2+ during hypoxia in spontaneously active vascular smooth muscle in rats.
Topics: Actin Cytoskeleton; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Calcium; Chlorides; Cy | 1993 |
Pharmacological modulation of the spasmogenic response to methylxanthines in guinea-pig trachea.
Topics: Animals; Caffeine; Calcium; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indometh | 1993 |
Involvement of ATP-sensitive K+ channels in the sustained coronary vasodilator response to adenosine in dogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Dogs; Female; Gl | 1993 |
Effect of diadenosine phosphates on human umbilical vessels: novel platelet-derived vasoconstrictors.
Topics: Arginine; Blood Platelets; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Enzyme Inhibit | 1995 |
The effects of theophylline and caffeine on the isolated rat diaphragm.
Topics: Animals; Caffeine; Diaphragm; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; M | 1995 |
Pharmacological activities of imidazo[1,2-alpha]pyrazine derivatives.
Topics: Adenosine; Animals; Calcium; Cardiovascular Agents; Cattle; Diuresis; Guinea Pigs; Heart Atria; Hear | 1995 |
Mechanism of theophylline-induced inotropic effects on foreshortened canine diaphragm.
Topics: Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Diaphragm; Dogs; In Vitro Techniqu | 1995 |
P2-purinoceptors mediating spasm of the isolated uterus of the non-pregnant guinea-pig.
Topics: Adenosine Triphosphate; Animals; Female; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smoo | 1996 |
Simultaneous measurement of cyclopentyladenosine-induced contraction and intracellular calcium in bronchial rings from allergic rabbits and it's antagonism.
Topics: Adenosine; Animals; Bronchi; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Musc | 1996 |
ATP and beta,gamma-methylene ATP produce relaxation of guinea-pig isolated trachealis muscle via actions at P1 purinoceptors.
Topics: Adenosine Triphosphate; Animals; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; | 1996 |
beta-Adrenoceptor agonists-induced desensitization in rat trachea.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Carbachol; Dinoprostone; In Vitro Techniques; Isoprote | 1995 |
Salbutamol potentiates the relaxant effects of selective phosphodiesterase inhibitors on guinea pig isolated trachea.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonists; Albuterol; Animals; Drug S | 1996 |
ATP modification of serotonin-induced contraction of the rat pulmonary artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenosine Triphosphate; Animals; Cyclic AMP; Male; Muscle Co | 1997 |
P1-purinoceptor-mediated vasodilatation and vasoconstriction in hypoxia.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Hypoxia; In Vitro Techniques; In | 1996 |
Adenosine depresses transmitter release but is not the basis for 'tetanic fade' at the neuromuscular junction of the rat.
Topics: Adenosine; Animals; Diaphragm; Electric Stimulation; Feedback; Female; In Vitro Techniques; Motor En | 1997 |
Effects of allocryptopine, an alkaloid isolated from Glaucium arabicum on rat isolated ileum and urinary bladder.
Topics: Alkaloids; Animals; Berberine Alkaloids; Female; Ileum; In Vitro Techniques; Male; Methylene Blue; M | 1997 |
Protective effect of three xanthine derivatives (theophylline, caffeine and pentoxifylline) against the cyclosporin A-induced glomerular contraction in isolated glomeruli and cultured mesangial cells.
Topics: Animals; Caffeine; Cells, Cultured; Cyclosporine; Fluorescent Antibody Technique, Indirect; Glomerul | 1997 |
cAMP protects endothelial barrier function independent of inhibiting MLC20-dependent tension development.
Topics: Cells, Cultured; Colforsin; Cyclic AMP; Electric Impedance; Endothelium, Vascular; Humans; Molecular | 1998 |
New beta-diketone and 3,5-dimethyl isoxazole derivatives of theophylline as potential bronchodilator agents.
Topics: Acetylcholine; Animals; Bronchi; Bronchodilator Agents; Chemical Phenomena; Chemistry, Physical; Fem | 1998 |
Effect of exogenous adenosine and its monophosphate on the contractile response to acetylcholine in the human isolated detrusor muscle strips.
Topics: Acetylcholine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; | 1998 |
Theophylline derivatives as potential histamine H3-receptor antagonists.
Topics: Animals; Guinea Pigs; Histamine Antagonists; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, | 1998 |
Muscle contraction-induced steal model in the anesthetized cat.
Topics: Anesthesia; Animals; Arteries; Blood Gas Analysis; Blood Pressure Determination; Cats; Electric Stim | 1998 |
Adrenergic-purinergic interactions on vasoconstrictor responses to periarterial electric nerve stimulation in canine splenic arteries.
Topics: Adenosine Triphosphate; Animals; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Musc | 1999 |
Comparison of the effects of selective III, IV and nonselective phosphodiesterase inhibitors on isolated tracheal preparations in streptozotocin-diabetic rats.
Topics: Amrinone; Animals; Carbachol; Cardiotonic Agents; Diabetes Mellitus, Experimental; Dose-Response Rel | 2000 |
Effects of the water soluble fraction from leaves of Ageratum conyzoides on smooth muscle.
Topics: Acetylcholine; Animals; Asteraceae; Calcium Chloride; Dose-Response Relationship, Drug; Drug Synergi | 2000 |
Effects of amylin and other peptide hormones on Na+-K+ transport and contractility in rat skeletal muscle.
Topics: Adrenomedullin; Amyloid; Animals; Biological Transport, Active; C-Peptide; Cyclic AMP; Insulin; Isle | 2000 |
The effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C(4)-induced contractions in passively sensitized human airways.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Antigens, Dermatophagoides; Benzam | 2000 |
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; | 2001 |
Role of lysophosphatidylcholine in the desensitization of beta-adrenergic receptors by Ca(2+) sensitization in tracheal smooth muscle.
Topics: Adenylate Cyclase Toxin; Adrenergic beta-Agonists; Amides; Animals; Bucladesine; Calcium; Cholera To | 2001 |
On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Carbachol; Diamines; Dose-Response Re | 2001 |
Comparative study of the contractile activity evoked by ATP and diadenosine tetraphosphate in isolated rat urinary bladder.
Topics: Adenosine Triphosphate; Animals; Atropine; Dinucleoside Phosphates; Dose-Response Relationship, Drug | 2002 |
Different effects of beta-adrenoceptor desensitization on inhibitory actions in guinea-pig trachealis.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; Dose-Response Relationship, Drug; Guinea Pigs; In Vitr | 2002 |
Effect of beta-adrenoceptor stimulators, papaverine and theophylline on guinea-pig trachea contracted by different drugs.
Topics: Adrenergic beta-Agonists; Animals; Drug Interactions; Guinea Pigs; Histamine; Imidazoles; Isoprotere | 1976 |
Pharmacological studies with adenine, adenosine and some phosphorylated derivatives on guinea-pig tracheal muscle.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoproteren | 1976 |
Tachyphylaxis to beta-adrenoceptor agonists in guinea pig airway smooth muscle in vivo and in vitro.
Topics: Adrenergic beta-Agonists; Aerosols; Airway Resistance; Animals; Drug Interactions; Female; Guinea Pi | 1977 |
Gastric relaxation by apomorphine and ATP in the conscious dog.
Topics: Adenosine Triphosphate; Animals; Apomorphine; Dogs; Female; Muscle Contraction; Muscle Relaxation; M | 1979 |
Release of chemical mediators from both allergic and non-allergic human leukocytes.
Topics: Allergens; Antigen-Antibody Complex; Cations, Divalent; Complement C3; Complement C5; Complement Sys | 1975 |
Analysis of the relationship between pharmacological inhibition of cyclic nucleotide phosphodiesterase and relaxation of canine tracheal smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterase | 1979 |
In vitro action of combined salbutamol and theophylline on anaphylactic contractions, mediator release and cyclic 3',5'-adenosine monophosphate in lung parenchyma.
Topics: Albuterol; Anaphylaxis; Animals; Cyclic AMP; Guinea Pigs; Histamine Release; In Vitro Techniques; In | 1979 |
Influence of the hormone analogue 13-NLE-molitin and of 1-methyl-3-isobutylxanthine on tone and cyclic 3',5'-AMP content of antral and duodenal muscles in the rabbit.
Topics: Animals; Cyclic AMP; Duodenum; Gastrointestinal Hormones; Muscle Contraction; Muscle Tonus; Muscle, | 1975 |
Cyclic adenosine monophosphate and vascular reactivity in spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Aorta; Blood Vessels; Bucladesine; Cyclic AMP; Hypertension; Isoproteren | 1975 |
[The action mechanism of trapidil (Rocornal)].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arteries; Blood Pressure; Guinea Pigs; Heart; In Vitro | 1975 |
[Mechanism of the antispasmogenic action of some substances that affect the 3', 5'-AMP system].
Topics: Acetylcholine; Animals; Cyclic AMP; Drug Interactions; Female; Guinea Pigs; Ileum; Imidazoles; In Vi | 1975 |
Adenosine inhibition of isolated rabbit ileum and antagonism by theophylline.
Topics: Adenosine; Animals; Binding Sites; Cyclic AMP; Depression, Chemical; Ileum; In Vitro Techniques; Mal | 1976 |
Azathioprine: effects on neuromuscular transmission.
Topics: Animals; Azathioprine; Cats; Cattle; Cyclic AMP; Muscle Contraction; Muscle Denervation; Neuromuscul | 1976 |
A role of cyclic nucleotides in neuromuscular transmission.
Topics: Adenosine; Alloxan; Animals; Axons; Bucladesine; Cats; Cyclic AMP; Dithionitrobenzoic Acid; Electric | 1976 |
Action of insulin and cell calcium: effect of ionophore A23187.
Topics: Animals; Anti-Bacterial Agents; Bucladesine; Caffeine; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; | 1976 |
A theory of the mechanism of cerebral vasospasm and its reversal, the role of calcium and cyclic AMP.
Topics: Blood Platelets; Blood Vessels; Brain; Bucladesine; Calcium; Cyclic AMP; Ischemic Attack, Transient; | 1976 |
Evidence for a prejunctional role of cyclic nucleotides in neuromuscular transmission.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bucladesine; Cats; Cyclic AMP; Cyclic GMP; Fluorides; | 1976 |
Cyclic 3',5'-adenosine monophosphate and bronchial tone.
Topics: Adenylyl Cyclases; Animals; Bronchi; Cyclic AMP; Dogs; Epinephrine; Female; In Vitro Techniques; Iso | 1977 |
The influence of the calcium antagonist fendiline on tone and motility of the guinea pig gut smooth muscle and the cAMP and cGMP concentrations of the isolated terminal ileum.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Digestive System; Female; Gastrointestinal Motility; Guine | 1977 |
Airway responses of the guinea pig in vivo and in vitro.
Topics: Aerosols; Animals; Bucladesine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; In | 1977 |
Effects of phenytoin on the cyclic nucleotide system in the motor nerve terminal.
Topics: Animals; Bucladesine; Calcium Chloride; Cats; Electric Stimulation; Evoked Potentials; Hindlimb; Mot | 1977 |
Urotensin I induced relaxation and intracellular cAMP content in the rat tail artery.
Topics: Animals; Arteries; Cyclic AMP; Drug Interactions; Fishes; In Vitro Techniques; Male; Muscle Contract | 1977 |
Presynaptic inhibitory actions of adenine nucleotides and adenosine on neurotransmission in the rat vas deferens.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Atropine; Depression, Chemical; Dip | 1977 |
Electrophysiological effects effects of prostaglandin F 2 alpha and E1 on the oviduct of the pregnant guinea pig in relation to Ca++.
Topics: Action Potentials; Animals; Bucladesine; Calcium; Cations, Divalent; Fallopian Tubes; Female; Guinea | 1978 |
Inhibitory effects of melatonin, prostaglandin E1, cyclic AMP, dibutyrylcyclic AMP and theophylline on rat seminiferous tubular contractility in vitro.
Topics: Animals; Bucladesine; Cyclic AMP; Male; Melatonin; Muscle Contraction; Muscle, Smooth; Prostaglandin | 1978 |
Pharmacological and biochemical activities of some monomethylxanthine and methyluric acid derivatives of theophylline and caffeine.
Topics: Animals; Caffeine; Dogs; Female; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smoot | 1978 |
Contribution of adrenergic and "purinergic" neurotransmission to contraction in rabbit detrusor.
Topics: Adenosine Triphosphate; Animals; Dipyridamole; Female; In Vitro Techniques; Male; Muscle Contraction | 1978 |
Beta-adrenoceptor stimulation and cyclic AMP levels in bovine tracheal muscle of old and young animals.
Topics: Acetylcholine; Age Factors; Animals; Carbachol; Cattle; Cyclic AMP; Histamine; Isoproterenol; Muscle | 1978 |
Evidence for the cell surface locus of presynaptic purine nucleotide receptors in the guinea-pig ileum.
Topics: Adenosine; Animals; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; | 1978 |
Presynaptic inhibitory actions of 2-substituted adenosine derivatives on neurotransmission in rat vas deferens: effects of inhibitors of adenosine uptake and deamination.
Topics: Adenosine; Animals; Atropine; Coformycin; Deamination; In Vitro Techniques; Male; Muscle Contraction | 1979 |
Cyclic nucleotides and neuromuscular transmission.
Topics: Adenylyl Cyclases; Animals; Axons; Bucladesine; Cats; Cyclic AMP; Epinephrine; Muscle Contraction; M | 1979 |
Apparent irrelevance of cyclic nucleotides to the relaxation of tracheal smooth muscle induced by theophylline.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Dogs; Guinea Pigs; Male; Muscle Contraction; Muscle Relaxa | 1979 |
The effects of adenosine and adenine nucleotides on the guinea-pig vas deferens: evidence for existence of purinergic receptors.
Topics: Action Potentials; Adenine Nucleotides; Adenosine; Animals; Guinea Pigs; In Vitro Techniques; Isatin | 1979 |
Inhibition of fundic strips from guinea-pig stomach: the effect of theophylline on the membrane potential, muscle contraction and ion fluxes.
Topics: Animals; Calcium; Cyclic AMP; Female; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Male; Membra | 1979 |
The role of calcium and cyclic AMP in the contractile action of angiotensin II upon rat descending colon.
Topics: Angiotensin II; Animals; Bucladesine; Calcium; Colon; Cyclic AMP; Imidazoles; In Vitro Techniques; I | 1979 |
On the mechanism of relaxation of tracheal muscle by theophylline and other cyclic nucleotide phosphodiesterase inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Cyclic AMP; Cyclic GMP; Drug Interactions; | 1979 |
Synthesis and biological evaluation of some 10-substituted 2,3-dihydroimidazo[2,1-b]quinazolin-5(10H)-ones, a new class of bronchodilators.
Topics: Animals; Bronchodilator Agents; Dogs; Female; Guinea Pigs; Hemodynamics; Histamine; Histamine H1 Ant | 1975 |
Histamine receptors in adipose tissue: involvement of cyclic adenosine monophosphate and the H2-receptor in the lipolytic response to histamine in isolated canine fat cells.
Topics: Adipose Tissue; Animals; Cyclic AMP; Dogs; Fatty Acids, Nonesterified; Guinea Pigs; Histamine; Hista | 1975 |
Inhibition of ATP-induced contraction in the guinea-pig urinary bladder in vitro and in vivo.
Topics: Adenosine; Adenosine Triphosphate; Amines; Animals; Female; Guinea Pigs; Indomethacin; Isoproterenol | 1979 |
Effects of cholinoceptor blocking drugs, adrenoceptor stimulants, and calcium antagonists on the transmurally stimulated guinea-pig urinary bladder in vitro and in vivo.
Topics: Adenosine; Animals; Calcium; Electric Stimulation; Female; Guinea Pigs; Muscle Contraction; Muscle, | 1979 |
Theophylline is not an antagonist of intramural inhibitory nerve activity in rabbit and guinea pig intestine [proceedings].
Topics: Animals; Guinea Pigs; In Vitro Techniques; Intestines; Muscle Contraction; Muscle, Smooth; Rabbits; | 1979 |
Combination bronchodilators: antagonism of airway smooth muscle contractions in vitro.
Topics: Acetylcholine; Airway Resistance; Albuterol; Animals; Bronchodilator Agents; Drug Combinations; Drug | 1979 |
Role of Ca2+ in genesis of lower esophageal sphincter tone and other active contractions.
Topics: Animals; Calcium; Esophagogastric Junction; Ethanol; Female; Lanthanum; Male; Muscle Contraction; Mu | 1979 |
Mechanisms of airway smooth muscle response to isoproterenol and theophylline.
Topics: Animals; Bronchi; Dogs; Guinea Pigs; Isoproterenol; Lung; Muscle Contraction; Muscle, Smooth; Rats; | 1979 |
Purine effects at the neuromuscular junction and their modification by theophylline, imidazole and verapamil.
Topics: Adenosine; Adenosine Triphosphate; Animals; Drug Interactions; Female; Imidazoles; In Vitro Techniqu | 1979 |
Relaxation of guinea-pig fundic strip by adenosine, adenosine triphosphate and electrical stimulation: lack of antagonism by theophylline or ATP treatment.
Topics: Adenosine; Adenosine Triphosphate; Animals; Electric Stimulation; Female; Guinea Pigs; In Vitro Tech | 1979 |
Theophylline antagonizes some effects of purines in the intestine but not those of intramural inhibitory nerve stimulation.
Topics: Animals; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Intestines; Male; Membrane | 1979 |
Adenosine-alpha, beta-methylene diphosphate effects in intestinal smooth muscle: sites of action and possible prostaglandin involvement.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; In Vitro Techniques; Muscle Contraction; Muscle | 1979 |
Effects of prostaglandin E1 on isolated dog renal artery.
Topics: Animals; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoproteren | 1979 |
Relaxations of guinea-pig fundic strip by adenosine, adenine nucleotides and electrical stimulation: antagonsism by theophylline and desensitization to adenosine and its derivatives.
Topics: Adenine Nucleotides; Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Con | 1977 |
Synthesis and pharmacological testing on some theophylline esters.
Topics: Acetylcholine; Animals; Guinea Pigs; In Vitro Techniques; Methods; Muscle Contraction; Muscle, Smoot | 1977 |
The myorelaxant effect of theophylline on smooth muscle cells of the afferent arterioles and glomerular tuft.
Topics: Animals; Arterioles; In Vitro Techniques; Kidney Glomerulus; Male; Muscle Contraction; Muscle Relaxa | 1978 |
The development of tachyphylaxis to electrical stimulation in guinea-pig ileal longitudinal muscles and the possible participation of adenosine and adenine nucleotides.
Topics: Acetylcholine; Adenine; Adenine Nucleotides; Adenosine; Animals; Dipyridamole; Electric Stimulation; | 1978 |
Relationship between theophylline-induced relaxation and excitation-contraction coupling in intestinal smooth muscle.
Topics: Action Potentials; Animals; Guinea Pigs; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle R | 1978 |
Pirbuterol, a selecttve beta2 adrenergic bronchodilator.
Topics: Acetylcholine; Albuterol; Anaphylaxis; Animals; Bronchodilator Agents; Cardiovascular System; Dogs; | 1978 |
The effect of intravenously administered proxyphylline and Baralgin on the contraction of the human gallbladder.
Topics: Adult; Benzophenones; Drug Therapy, Combination; Female; Gallbladder Diseases; Humans; Injections, I | 1978 |
[Influence of phosphorylation on the properteis of biological active compounds (author's transl)].
Topics: Animals; Bronchodilator Agents; Diuretics; Guinea Pigs; Hemodynamics; In Vitro Techniques; Mice; Mus | 1978 |
The effect of theophylline on the responses of the guinea-pig urinary bladder to nerve stimulation, adenosin 5' triphosphate and histamine.
Topics: Adenosine Triphosphate; Animals; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Hista | 1978 |
Effects of gastrointestinal hormones on the electrical and mechanical activity of the cat stomach.
Topics: Action Potentials; Animals; Atropine; Caffeine; Cats; Cholecystokinin; Gastrins; Gastrointestinal Ho | 1977 |
The inhibitory effect of adenosine and related nucleotides on the release of acetylcholine.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Animals; Cerebral Cortex; Cholecystokinin; Electric S | 1976 |
[Structure and organization of the contractile proteins at the level of the Z and M bands in the sartorius muscles of Rana esculenta treated with methylxanthine (MX)].
Topics: Animals; Caffeine; Muscle Contraction; Muscle Proteins; Muscles; Rana esculenta; Theophylline; Xanth | 1976 |
Rabbit testicular contractions: bimodal interaction of prostaglandin E1 with other agonists.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; In Vitro Tech | 1975 |
Antagonism of the uterotonic action of oxytocin in vitro.
Topics: Albuterol; Animals; Drug Interactions; Drug Synergism; Epinephrine; Female; In Vitro Techniques; Iso | 1975 |
The inhibitory effects of prostaglandin E1 on guinea-pig ureter.
Topics: Animals; Calcium; Catecholamines; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Lanthanum; | 1975 |
Selective antagonism of the intesinal stimulatory effects of morphine by isoproterenol prostalglandin E1 and theophylline.
Topics: Acetylcholine; Animals; Depression, Chemical; Dogs; Female; In Vitro Techniques; Intestines; Isoprot | 1975 |
The effect of ATP and related compounds on spontaneous mechanical activity in the rat portal vein.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adeno | 1975 |
Inhibition of acetylcholine release from cholinergic nerves by adenosine, adenine nucleotides and morphine: antagonism by theophylline.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Animals; Depression, Chemical; Guinea Pigs; In Vitro | 1976 |
[Effects of theophylline on the respiratory system].
Topics: Animals; Asthma; Bronchodilator Agents; Cardiovascular System; Diaphragm; Histamine Release; Humans; | 1992 |
Rabbit isolated vas deferens possess A1 and A2 adenosine receptors.
Topics: Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purine | 1992 |
Pharmacological characterization of adenosine A1 and A2 receptors in the bladder: evidence for a modulatory adenosine tone regulating non-adrenergic non-cholinergic neurotransmission.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Autonomic Nervous Sys | 1992 |
Comparative study on the mechanism of bradykinin potentiation induced by bradykinin-potentiating peptide 9a, enalaprilat and kinin-potentiating peptide.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Bradykinin; Drug Synergism; Enalaprilat; Female; Gu | 1992 |
Presynaptic A1-purinoceptor-mediated inhibitory effects of adenosine and its stable analogues on the mouse hemidiaphragm preparation.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diaphragm; | 1992 |
Effects of broxaterol and theophylline on fatigued canine diaphragm in vivo. A randomized, controlled study.
Topics: Adrenergic beta-Agonists; Animals; Diaphragm; Dogs; Dose-Response Relationship, Drug; Electric Stimu | 1992 |
Relaxation of soman-induced contracture of airway smooth muscle in vitro.
Topics: Acetylcholine; Adrenergic beta-Agonists; Albuterol; Animals; Colforsin; Dogs; Dose-Response Relation | 1992 |
The role of cyclic AMP in non-adrenergic non-cholinergic contraction in guinea-pig bronchi.
Topics: Animals; Autonomic Nervous System; Benzopyrans; Bronchi; Bronchodilator Agents; Bucladesine; Colfors | 1992 |
Effect of phosphodiesterase inhibitors on bovine ciliary muscle and outflow facility.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Aqueous Humor; Caffeine; Cattle; Cil | 1992 |
Effect of compounds from Mandevilla velutina on bradykinin-mediated contractile and relaxant responses of the isolated guinea pig trachea.
Topics: Animals; Bradykinin; Carbachol; Dinoprost; Epithelial Cells; Epithelium; Female; Guinea Pigs; Histam | 1992 |
Caffeine and theophylline contractures in tonic skeletal muscle fibers of the frog.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Contracture; Dose-Response Relationship, Drug; | 1992 |
Influence of osmolarity of solutions used for K+ contraction on relaxant responses to pinacidil, verapamil, theophylline and terbutaline in isolated airway smooth muscle.
Topics: Animals; Guanidines; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle | 1992 |
Theophylline and magnesium inhibit the contraction elicited with ciclosporin and angiotensin II in mesangial cell cultures.
Topics: Angiotensin II; Animals; Bucladesine; Cells, Cultured; Cyclosporins; Dinoprostone; Dose-Response Rel | 1991 |
Theophylline, fatigue, and diaphragm contractility: cellular levels of 45Ca and cAMP.
Topics: Animals; Calcium; Cyclic AMP; Diaphragm; In Vitro Techniques; Male; Muscle Contraction; Rats; Rats, | 1991 |
Pharmacological studies in animals of beta-hydroxyethyltheophylline, the major metabolite of doxofylline in humans.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acetylcholine; Animals; Antitussive Agents; Blood Pressure; Bro | 1991 |
Adenosine enhances antigen-induced bronchoconstriction and histamine release in rat isolated lungs.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antigens; Bronchi; Histamine Release; In Vitr | 1990 |
A study of the purinoceptors mediating contraction in the rat colon.
Topics: Adenosine; Animals; Colon; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purines; R | 1990 |
Leukotriene receptor antagonism and augmentation of beta-receptor-mediated events by LY171883.
Topics: 1-Methyl-3-isobutylxanthine; Acetophenones; Adrenergic beta-Agonists; Animals; Bronchodilator Agents | 1990 |
Endothelium-dependent and endothelium-independent vasodilatation of the hepatic artery of the rabbit.
Topics: Animals; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Hepatic Artery; Immunohistochemistr | 1991 |
Effects of theophylline on canine diaphragmatic contractility and fatigue.
Topics: Animals; Diaphragm; Dogs; Dose-Response Relationship, Drug; In Vitro Techniques; Muscle Contraction; | 1991 |
Role of the epithelium in airway smooth muscle responses to relaxant agonists.
Topics: Albuterol; Animals; Arachidonic Acid; Bronchodilator Agents; Diffusion; Epithelium; Guinea Pigs; In | 1991 |
Purinergic modulation of field stimulation responses of rat and human vas deferens smooth muscle.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Electric St | 1991 |
Effects of dantrolene on the responses to methylxanthines in the isolated guinea-pig trachea.
Topics: Acetylcholine; Albuterol; Animals; Caffeine; Calcium; Dantrolene; Female; Guinea Pigs; Indomethacin; | 1991 |
The effects of electrical stimulation, adenosine and adenosine-5'-triphosphate (ATP) on mouse rectal muscle.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Atropine; Dipyridamole; Drug Interactions | 1991 |
Isoproterenol activation of prostaglandin production in guinea-pig airway muscle preparations from immature and mature animals.
Topics: Aging; Animals; Bronchi; Dinoprost; Dinoprostone; Enzyme Activation; Guinea Pigs; Histamine; Isoprot | 1991 |
Doxofylline differs from methylxanthines in its movement of cytosolic calcium.
Topics: Aminophylline; Animals; Binding Sites; Blood Platelets; Calcium; Cytosol; Diltiazem; Male; Muscle Co | 1991 |
Peripheral type benzodiazepine receptors and response to adenosine on the guinea-pig isolated trachea.
Topics: Adenosine; Animals; Benzodiazepines; Clonazepam; Diazepam; Dipyridamole; Drug Synergism; GABA-A Rece | 1990 |
Evidence against purines being neurotransmitters of non-adrenergic, non-cholinergic nerves in rat duodenum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Autonomi | 1990 |
Abnormalities in airway smooth muscle in fatal asthma. A comparison between trachea and bronchus.
Topics: Acetylcholine; Adult; Asthma; Bronchi; Bronchoconstriction; Electric Stimulation; Female; Histamine; | 1991 |
The effect of theophylline on hypoxic, hypercapnic hamster diaphragm muscle in vitro.
Topics: Acidosis, Respiratory; Animals; Cell Hypoxia; Cricetinae; Diaphragm; Hypercapnia; Membrane Potential | 1991 |
Organic calcium channel antagonists provoke acetylcholine receptor autodesensitization on train stimulation of motor nerve.
Topics: Animals; Bungarotoxins; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Diaph | 1990 |
[The relaxation of the coronary artery smooth muscles under the action of a high-potassium solution].
Topics: Animals; Cattle; Coronary Vessels; Dose-Response Relationship, Drug; In Vitro Techniques; Isotonic S | 1990 |
Adenosine receptor antagonism attenuates angiotensin II effects on adrenergic neurotransmission in the rabbit isolated vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Angiotensin II; Animals; Electric Stimulation; In Vitro Technique | 1990 |
The role of adenosine in exercise hyperaemia of the gracilis muscle in anaesthetized cats.
Topics: Adenosine; Animals; Cats; Hyperemia; Leg; Muscle Contraction; Muscles; Physical Exertion; Regional B | 1990 |
Theophylline minimally alters contractile properties of canine diaphragm in vitro.
Topics: Animals; Diaphragm; Diffusion; Dogs; Fatigue; In Vitro Techniques; Models, Biological; Muscle Contra | 1990 |
Effects of theophylline (T) on diaphragmatic contractility in dogs.
Topics: Animals; Diaphragm; Dogs; Muscle Contraction; Theophylline | 1990 |
Abnormalities in airway smooth muscle in fatal asthma.
Topics: Acetylcholine; Adult; Asthma; Cholinergic Fibers; Electric Stimulation; Female; Histamine; Humans; I | 1990 |
[Effect of shakuyaku-extract on electrical stimulation induced contraction of guinea pig ileum].
Topics: Adenosine; Animals; Depression, Chemical; Drugs, Chinese Herbal; Electric Stimulation; Guinea Pigs; | 1990 |
Activities of caffeine, theophylline, and enprofylline analogs as tracheal relaxants.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Guinea Pigs; In Vitro Techniques; Male; | 1990 |
Pharmacological treatment of respiratory insufficiency.
Topics: Animals; Digitalis; Dogs; Humans; Lung Diseases, Obstructive; Muscle Contraction; Plants, Medicinal; | 1990 |
Effect of theophylline on respiratory muscle function.
Topics: Aminophylline; Animals; Calcium; Cell Membrane; Diaphragm; Dogs; Humans; In Vitro Techniques; Ion Ch | 1985 |
Effects of bronchoconstrictors and bronchodilators on a novel human small airway preparation.
Topics: Adenosine; Adenosine Triphosphate; Bronchi; Bronchodilator Agents; Carbachol; Histamine; Humans; In | 1985 |
Apparent enhancement of cholinergic transmission in rabbit bronchi via adenosine A2 receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bronchi; Electric Stimulation; Female; In Vit | 1986 |
Animal pharmacology of the selective histamine H1-receptor antagonist tazifylline.
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Bronchodilator Agents; Dogs; Female; Gastric Acid | 1986 |
The relation between effects of adenosine, theophylline and enprofylline on the contractility of sensitized guinea-pig lung strips.
Topics: Adenosine; Animals; Antigens; Bronchodilator Agents; Dipyridamole; Female; Guinea Pigs; Histamine Re | 1987 |
Stimulation of acetylcholine release from myenteric neurons of guinea pig small intestine by forskolin and cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Buclade | 1987 |
Decreased contractile response after exposure of the rat aorta to Db cAMP or IBMX.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifl | 1987 |
Role of extracellular calcium in the effects of substance P and neurokinin A on guinea pig trachea and human bronchus.
Topics: Animals; Bronchi; Calcium; Guinea Pigs; Humans; In Vitro Techniques; Isoproterenol; Male; Muscle Con | 1988 |
Altered effect of BAY K 8644 after exposure of the rat aorta to IBMX or Db cAMP.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifl | 1988 |
On the adenosine receptor and adenosine inactivation at the rat diaphragm neuromuscular junction.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Diaphragm; Evoked Potentials; Fe | 1988 |
Acetate causes endothelium-independent increases in cyclic AMP in rat caudal artery.
Topics: 1-Methyl-3-isobutylxanthine; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisot | 1988 |
Diazepam enhances the inhibitory action of adenosine on transmission at the frog neuromuscular junction.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diazepam; Dipyridamole; Drug Synergism; In Vi | 1989 |
Analysis of the relaxant effects of AH 21-132 in guinea-pig isolated trachealis.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Acetylcholine; Animals; Female; Guinea Pigs; Histamine; | 1989 |
A possible mechanism of action of tetramethylpyrazine on vascular smooth muscle in rat aorta.
Topics: Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Female; In Vitro Techniques | 1989 |
Comparison between sympathetic adrenergic and purinergic transmission in the dog mesenteric artery.
Topics: Adenosine Triphosphate; Animals; Cocaine; Dogs; Female; Imidazoles; In Vitro Techniques; Male; Mesen | 1989 |
Putative mechanisms involved in excitatory and inhibitory effects of somatostatin on intestinal motility.
Topics: Acetylcholine; Animals; Bicuculline; Electric Stimulation; Female; gamma-Aminobutyric Acid; Gastroin | 1989 |
Theophylline does not increase maximal tetanic force or diaphragm endurance in vitro.
Topics: Animals; Caffeine; Cricetinae; Diaphragm; Electric Stimulation; Male; Mesocricetus; Muscle Contracti | 1989 |
Pharmacological characterization of neural mechanisms regulating mucosal ion transport in mouse jejunum.
Topics: Action Potentials; Animals; Atropine; Biological Transport; Carbachol; Dimethylphenylpiperazinium Io | 1989 |
The influence of xanthines on the contractile responses of PGF2 alpha and PGD2 in human parenchymal strips.
Topics: Bronchodilator Agents; Dinoprost; Histamine; Humans; Lung; Muscle Contraction; Muscle, Smooth; Prost | 1989 |
Mechanisms involved in the action of prostaglandins as modulators of neurotransmission.
Topics: Acetylcholine; Adenosine; Animals; Blood Pressure; Dilazep; Electric Stimulation; Female; Heart Rate | 1989 |
Doxofylline exerts a prophylactic effect against bronchoconstriction and pleurisy induced by PAF.
Topics: Airway Resistance; Anesthesia; Animals; Binding, Competitive; Bronchi; Bronchodilator Agents; Female | 1989 |
Postnatal changes in response to adenosine and adenine nucleotides in rat duodenum.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Duodenum; Female; | 1989 |
On the nature of endogenous purines modulating cholinergic neurotransmission in the guinea-pig ileum.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; AMP Deaminase; Animals; Cholinergic Fibers; Ele | 1987 |
Endogenous purines may modulate adrenergic neurotransmission in the human fallopian tube.
Topics: Adrenergic Fibers; Fallopian Tubes; Female; Humans; In Vitro Techniques; Muscle Contraction; Norepin | 1988 |
Pharmacological properties of a new antiasthmatic xanthine derivative devoid of central stimulatory activity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Asthma; Behavior, Animal; Blood Pressure; Bronchodilat | 1987 |
The mechanism of action of AMP-induced inhibition of sympathetic neurotransmission in the isolated vas deferens of the rat and guinea-pig.
Topics: Action Potentials; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro T | 1988 |
Presynaptic inhibition of sympathetic fibers participating in vasodilatation in response to K+-induced contraction of frog skeletal muscle.
Topics: Adenosine; Animals; Arterioles; Biological Transport; Dipyridamole; Muscle Contraction; Muscle, Smoo | 1988 |
Antagonism by clonidine of the adenosine-induced inhibition of the twitch contraction of the guinea-pig Oddi sphincter.
Topics: Adenosine; Alprostadil; Ampulla of Vater; Animals; Clonidine; Dipyridamole; Electric Stimulation; Gu | 1985 |
[Effect of beta-agonists on membrane potentials of isolated smooth muscle of the guinea pig trachea].
Topics: Adrenergic beta-Agonists; Animals; Bucladesine; Catecholamines; Colforsin; Guinea Pigs; In Vitro Tec | 1985 |
Beta agonist-induced desensitization in pig bronchus.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Airway Resistance; Animals; Bronchi; Colforsi | 1986 |
Effects of BN 52063 and other agents inhibiting platelet-activating factor-induced contractile responses in rat portal vein.
Topics: Albuterol; Animals; Colforsin; In Vitro Techniques; Lactones; Male; Muscle Contraction; Muscle, Smoo | 1988 |
Fenspiride and relaxation of tracheobronchial musculature. Mechanism of action.
Topics: Animals; Bronchi; Guinea Pigs; Humans; Muscle Contraction; Muscle Relaxation; Spiro Compounds; Theop | 1988 |
Diltiazem, verapamil, and nifedipine inhibit theophylline-enhanced diaphragmatic contractility.
Topics: Animals; Biological Transport; Calcium; Calcium Channel Blockers; Diaphragm; Diltiazem; Male; Muscle | 1989 |
Different innervation mechanisms between the lesser and greater curvature of guinea pig antrum.
Topics: Animals; Apamin; Atropine; Chymotrypsin; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Cont | 1989 |
Fast deactivation of guinea-pig isolated ileum to C5adesArg: a possible cyclic AMP-dependent mechanism.
Topics: Animals; Complement C5; Complement C5a, des-Arginine; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate | 1985 |
On the mechanism of action of theophylline and caffeine.
Topics: Adenosine; Asthma; Caffeine; Calcium; Cyclic AMP; Humans; Muscle Contraction; Receptors, Cell Surfac | 1985 |
Theophylline-sensitive modulation of non-cholinergic excitatory neurotransmission in the guinea-pig ileum.
Topics: Adenosine; Animals; Atropine; Autonomic Nervous System; Electric Stimulation; Guinea Pigs; Ileum; In | 1985 |
Effects of caffeine and 8-phenyltheophylline on the actions of purines and opiates in the guinea-pig ileum.
Topics: Adenosine; Animals; Caffeine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contra | 1986 |
Dual effects of adenosine and adenosine analogues on motor activity of the human fallopian tube.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Fallopian Tubes; Female; Hum | 1985 |
Adenine nucleotides and 5-hydroxytryptamine released by aggregating platelets inhibit adrenergic neurotransmission in canine coronary artery.
Topics: Adenosine Diphosphate; Animals; Arteries; Coronary Vessels; Dinoprost; Dogs; Electric Stimulation; M | 1986 |
Influence of the epithelium on responsiveness of guinea-pig isolated trachea to contractile and relaxant agonists.
Topics: Acetylcholine; Animals; Asthma; Autoradiography; Carbachol; Cimetidine; Colforsin; Dose-Response Rel | 1986 |
Affinity of various purine nucleosides for adenosine receptors on purified myenteric varicosities compared to their efficacy as presynaptic inhibitors of acetylcholine release.
Topics: Acetylcholine; Animals; Binding, Competitive; Cell Fractionation; Female; Guinea Pigs; In Vitro Tech | 1986 |
Effects of relaxants on electrical and mechanical activities in the guinea-pig tracheal muscle.
Topics: Animals; Bucladesine; Colforsin; Epinephrine; Female; Guinea Pigs; In Vitro Techniques; Isoprotereno | 1986 |
Arylazido aminopropionyl ATP (ANAPP3): interaction with adenosine receptors in longitudinal smooth muscle of the guinea-pig ileum.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Azides; Electric Stimulation; Guine | 1986 |
Cyclic AMP inhibits increased collagen production by cyclically stretched smooth muscle cells.
Topics: Animals; Bucladesine; Collagen; Culture Techniques; Cyclic AMP; Muscle Contraction; Muscle Proteins; | 1987 |
Concentration-dependent interaction of theophylline with d-tubocurarine.
Topics: Acetylcholine; Animals; Cyclic AMP; Drug Interactions; Male; Muscle Contraction; Neuromuscular Junct | 1987 |
[Theophylline-induced changes in the presynaptic effects of adenosine, baclofen, clofelin and morphine in the myenteric plexus of the guinea pig].
Topics: Adenosine; Animals; Baclofen; Clonidine; Drug Interactions; Guinea Pigs; In Vitro Techniques; Morphi | 1987 |
Breakdown of phosphoinositides in airway smooth muscle: lack of influence of anti-asthmatic drugs.
Topics: Animals; Carbachol; Cattle; Dexamethasone; Histamine; Hydrolysis; Isoproterenol; Muscle Contraction; | 1987 |
Relaxation of isolated corpus cavernosum induced by smooth-muscle relaxant drugs. A comparative study.
Topics: Adult; Aged; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; | 1988 |
Involvement of P1-purinoreceptors in the relaxing effect of adenosine in rat duodenum.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Duodenum; In Vitro Techniques; Male; Muscle Co | 1988 |
Slowing of relaxation in the fatiguing hamster diaphragm is enhanced by theophylline.
Topics: Animals; Caffeine; Calcium; Cricetinae; Diaphragm; In Vitro Techniques; Mesocricetus; Muscle Contrac | 1988 |
Effect of theophylline on the velocity of diaphragmatic muscle shortening.
Topics: Animals; Cricetinae; Diaphragm; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Tec | 1988 |
The use of the internal perimeter to compare airway size and to calculate smooth muscle shortening.
Topics: Carbachol; Epithelium; Humans; Muscle Contraction; Muscle, Smooth; Theophylline; Trachea | 1988 |
Doxofylline and theophylline are xanthines with partly different mechanisms of action in animals.
Topics: Adenosine; Aminophylline; Animals; Diuresis; Gastric Acid; Gastric Mucosa; Guinea Pigs; In Vitro Tec | 1988 |
Parasympathetic depression of vas deferens contraction in the guinea-pig involves adenosine receptors.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Mal | 1988 |
Effects of alpha,beta-methylene ATP on biphasic responses of rat vas deferens.
Topics: Adenosine Triphosphate; Animals; Dioxanes; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; | 1987 |
Adenosine 5'-triphosphate release evoked by electrical nerve stimulation from the guinea-pig gallbladder.
Topics: Adenosine Triphosphate; Animals; Barium; Barium Compounds; Chlorides; Electric Stimulation; Female; | 1987 |
Neuropeptide Y inhibits excitatory enteric neurons supplying the circular muscle of the guinea pig small intestine.
Topics: Animals; Apamin; Atropine; Ceruletide; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship | 1987 |
Blockade by theophylline of capsaicin-induced motor effects in guinea-pig airways.
Topics: Acetylcholine; Animals; Bronchi; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs | 1987 |
The role of myogenic relaxation, adenosine and prostaglandins in human forearm reactive hyperaemia.
Topics: Adenosine; Adult; Arteries; Constriction; Female; Forearm; Humans; Ibuprofen; Male; Muscle Contracti | 1987 |
Does endogenous adenosine modulate the release of acetylcholine from motor nerve during single and repetitive stimulations in the mouse diaphragm?
Topics: Acetylcholine; Adenosine; Animals; Dipyridamole; Electric Stimulation; In Vitro Techniques; Membrane | 1987 |
Agonist interactions at the calcium pools in skinned and unskinned canine tracheal smooth muscle.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Dogs; Female; Histamine; In Vitro Techniques; Isometric C | 1987 |
Quantitative measurement of smooth muscle shortening in isolated pig trachea.
Topics: Airway Resistance; Animals; Carbachol; Cartilage; In Vitro Techniques; Mathematics; Muscle Contracti | 1987 |
Comparative effects of theophylline and adenosine on respiratory skeletal and smooth muscle.
Topics: Adenosine; Animals; Diaphragm; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Muscles; Respiration | 1986 |
Effects of theophylline on isolated diaphragmatic fibers. A model for pharmacologic studies on diaphragmatic contractility.
Topics: Animals; Diaphragm; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Rats; Rats, Inbred Stra | 1986 |
Actions and interactions of adenosine, theophylline and enprofylline on the guinea-pig spirally cut trachea.
Topics: Adenosine; Animals; Bronchodilator Agents; Carbachol; Drug Interactions; Female; Guinea Pigs; Histam | 1986 |
Suppression by 5'-methylthioadenosine of histamine or leukotriene-induced contraction in isolated guinea pig tracheal rings.
Topics: Adenosine; Animals; Deoxyadenosines; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Hi | 1986 |
Effects of theophylline on small human placental arteries in vitro.
Topics: Dinoprost; Dinoprostone; Female; Humans; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; | 1985 |
Grip strength test and infrared thermometry as non-invasive methods to complement acute toxicity data in mice.
Topics: Animals; Calorimetry; Diazepam; Dose-Response Relationship, Drug; Mice; Muscle Contraction; Pentobar | 1985 |
Fatigue in frog skeletal muscle fibres and effects of methylxanthine derivatives.
Topics: Animals; Caffeine; Diethylstilbestrol; Electric Stimulation; Muscle Contraction; Muscles; Rana tempo | 1985 |
"On" and "off" responses of guinea pig ureter.
Topics: Animals; Calcium; Edetic Acid; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Magne | 1985 |
Respiratory muscle failure: fatigue or weakness? The role of theophylline.
Topics: Humans; Muscle Contraction; Muscular Diseases; Theophylline | 1986 |
Effect of theophylline on membrane potential and contractile force in hamster diaphragm muscle in vitro.
Topics: Animals; Cell Membrane; Cricetinae; Diaphragm; Membrane Potentials; Mesocricetus; Muscle Contraction | 1986 |
Effect of calcium entry blockers and adenosine on the relaxation of large and small coronary arteries.
Topics: Adenosine; Animals; Arteries; Calcium Channel Blockers; Cattle; Coronary Vessels; Dose-Response Rela | 1986 |
Cellular Ca2+ monitored by aequorin in adenosine-mediated smooth muscle relaxation.
Topics: Adenosine; Aequorin; Animals; Body Fluids; Calcium; Dose-Response Relationship, Drug; Electric Stimu | 1985 |
Response and sensitivity of isolated human pulmonary muscle preparations to pharmacological agents.
Topics: Albuterol; Bronchi; Histamine; Humans; In Vitro Techniques; Isoproterenol; Lung; Male; Muscle Contra | 1985 |
Effect of adenosine 5'triphosphate (ATP) on the isolated rectum of the rainbow lizard Agama agama.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Chloride; Carbachol; Dipyridamole; In Vitro Techni | 1985 |
A possible explanation for a greater discrepant suppression by adenosine and N6-cyclohexyl adenosine of the guinea-pig ileal contraction.
Topics: Adenosine; Animals; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; | 1985 |
Possibilities for adenosine modulation of peristaltic reflex in guinea pig isolated ileum.
Topics: Adenosine; Animals; Atropine; Autoradiography; Dipyridamole; Gastrointestinal Motility; Guinea Pigs; | 1985 |
Mechanism of histamine release from guinea-pig lung by soluble immune complexes. II. Role of anaphylatoxin.
Topics: Anaphylaxis; Animals; Antigen-Antibody Complex; Biological Assay; Dose-Response Relationship, Drug; | 1974 |
The action of catecholamines on guinea-pig taenia coli.
Topics: Animals; Calcium; Catecholamines; Colon; Electric Conductivity; Estrogens; Female; Guinea Pigs; In V | 1973 |
Relaxation of catch in a molluscan smooth muscle. I. Effects of drugs which act on the adenyl cyclase system.
Topics: Acetylcholine; Adenine Nucleotides; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Adrenergic beta | 1972 |
Evidence for a non-adrenergic inhibitory nervous pathway in guinea-pig trachea.
Topics: Animals; Atropine; Cyclic AMP; Electric Stimulation; Guanethidine; Guinea Pigs; Hydroxydopamines; Im | 1973 |
[Role of sympathetic nerve system and skeletal muscles in theophylline-induced thermogenesis. Studies on non-shivering thermogenesis. 2 (author's transl)].
Topics: Acclimatization; Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; | 1974 |
An analysis of the alpha- and beta-effects of isoprenaline on the isolated nictitating membraen.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Cats; Dose-Response Relationship, Drug | 1974 |
Inhibition of the oxytocic action of prostaglandin F2alpha on pregnant rabbit uterus by intra-aortic infusion of theophylline in vivo.
Topics: Anesthesia, General; Animals; Aorta, Abdominal; Female; Injections, Intra-Arterial; Muscle Contracti | 1974 |
[Influence of reserpine, propranolol, hexamethonium and adrenalectomy on the chronotropic actions of theophylline and caffeine].
Topics: Animals; Atrial Function; Caffeine; Depression, Chemical; Heart Atria; Heart Rate; Hexamethonium Com | 1968 |
[On the effect of dibutyryl-3',5'-AMP on the isolated heart].
Topics: Adenine Nucleotides; Animals; Coronary Vessels; Guinea Pigs; Heart; Hemodynamics; In Vitro Technique | 1968 |
[Influence of divalent Mn ions on the positive inotropic effect of some drugs in isolated guinea pig atria].
Topics: Animals; Calcium; Cardanolides; Electric Stimulation; Epinephrine; Guinea Pigs; Heart; Heart Atria; | 1969 |
[Influence of manganese ions on the positive inotropic effect of adrenaline, theophylline and digitoxigenin in isolated guinea pig atria].
Topics: Animals; Calcium; Cardanolides; Depression, Chemical; Epinephrine; Guinea Pigs; Heart; Heart Atria; | 1969 |
Proceedings: Prevention by Ca-antagonistic compounds (verapamil, D 600) of coronary smooth muscle contractures due to treatment with cardiac glycosides.
Topics: Animals; Caffeine; Calcium; Cardiac Glycosides; Coronary Vessels; Dipyridamole; In Vitro Techniques; | 1974 |
Metabolic actions associated with stimulation of alpha- and beta-receptors for adrenaline in smooth muscle.
Topics: Adenosine Triphosphate; Anilides; Animals; Cell Membrane Permeability; Colon; Cyclic AMP; Dibenzylch | 1968 |
The effect of theophylline on amine-induced cardiac phosphorylase activation and cardiac contractility.
Topics: Animals; Atropine; Calcium; Cyclic AMP; Drug Synergism; Female; Glucosyltransferases; Heart; Hemodyn | 1969 |
The influence of oligomycin on the actions of epinephrine and theophylline upon the perfused rat heart.
Topics: Adenine Nucleotides; Animals; Biological Transport; Calcium; Cyclic AMP; Depression, Chemical; Drug | 1969 |
[On the mechanism of the cardiac effects of 2-bromo-LSD].
Topics: Animals; Bromine; Carbon Isotopes; Cyclic AMP; Depression, Chemical; Guinea Pigs; Heart; In Vitro Te | 1969 |
The effects of theophylline, diazoxide and imidazole on isoproterenol-induced inhibition of the rabbit ileum.
Topics: Animals; Cyclic AMP; Diazoxide; Ileum; Imidazoles; In Vitro Techniques; Isoproterenol; Muscle Contra | 1969 |
The mechanism of potentiation of inotropic responses to phenylephrine by theophylline.
Topics: Animals; Anura; Drug Synergism; Heart; In Vitro Techniques; Muscle Contraction; Myocardium; Phenylep | 1969 |
Influence of endogenous and exogenous cyclic 3',5'-AMP on contractile responses induced by oxytocin and calcium in isolated rat uterus.
Topics: Adenine Nucleotides; Animals; Calcium; Cyclic AMP; Epinephrine; Female; In Vitro Techniques; Muscle | 1970 |
Cardiostimulatory effects of cyclic 3',5'-adenosine monophosphate and its acylated derivatives.
Topics: Adenine Nucleotides; Adenylyl Cyclases; Animals; Cell Membrane; Coronary Vessels; Cyclic AMP; Female | 1970 |
The effect of isoprenaline, theophylline and adenosine 3', 5'-monophosphate on the isolated vas deferens of the guinea-pig.
Topics: Adenine Nucleotides; Animals; Cyclic AMP; Drug Synergism; Electric Stimulation; Guinea Pigs; In Vitr | 1970 |
The influence of cyclic 3',5' -AMP on contractile responses induced by vasopressin in isolated rat uterus.
Topics: Adenine Nucleotides; Animals; Cyclic AMP; Epinephrine; Female; In Vitro Techniques; Muscle Contracti | 1971 |
Thick filaments in vascular smooth muscle.
Topics: Aldehydes; Animals; Blood Vessels; Buffers; Calcium; Cell Membrane; Cytoplasmic Granules; Endoplasmi | 1971 |
Effects of theophylline on the contractile activity of taenia coli.
Topics: Animals; Calcium; Cyclic AMP; Depression, Chemical; Guinea Pigs; In Vitro Techniques; Intestine, Lar | 1971 |
The possible role of cyclic AMP in some actions of cholera toxin.
Topics: Animals; Chick Embryo; Cholera; Cyclic AMP; Cyclic GMP; Dogs; Enterotoxins; Fetal Heart; In Vitro Te | 1971 |
Cyclic AMP and smooth muscle function.
Topics: Adenylyl Cyclases; Animals; Aorta, Abdominal; Aorta, Thoracic; Arteries; Cyclic AMP; Depression, Che | 1971 |
Potentiation of the inotropic effects of glucagon by theophylline.
Topics: Animals; Buffers; Cats; Cyclic AMP; Drug Interactions; Drug Synergism; Glucagon; In Vitro Techniques | 1971 |
Activities in vitro of 8-substituted derivatives of adenosine-3',5'-cyclic monophosphate on guinea pig trachea and rat portal vein.
Topics: Amines; Animals; Azides; Benzyl Compounds; Butyrates; Cyclic AMP; Female; Guinea Pigs; Hepatic Veins | 1971 |
Actions of quazodine (MJ1988) on smooth muscle.
Topics: Animals; Aorta; Cats; Depression, Chemical; Duodenum; Electric Stimulation; Female; Guinea Pigs; Ile | 1971 |
Cyclic adenosine 3',5' monophosphate levels in rat myometrium under the influence of epinephrine, prostaglandins and oxytocin, correlations with uterus motility.
Topics: Adenine; Adenylyl Cyclases; Animals; Carbon Isotopes; Chromatography; Cyclic AMP; Drug Antagonism; E | 1971 |
Accumulation of adenosine 3',5'-monophosphate and relaxation in the rat uterus in vitro.
Topics: Animals; Butyrates; Cyclic AMP; Depression, Chemical; Diazoxide; Drug Interactions; Female; Fluoride | 1971 |
Effects of theophylline on myocardial mechanics.
Topics: Animals; Biomechanical Phenomena; Cats; Cyclic AMP; Elasticity; Heart; In Vitro Techniques; Muscle C | 1972 |
Phenylephrine effects on cardiac contractility adenyl cyclase, and phosphorylase.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Drug Antagonism; Epinephrine; Female; Fluorides; Glucosyltra | 1972 |
Cyclic nucleotide phosphodiesterase inhibition and vascular smooth muscle relaxation.
Topics: Animals; Aorta, Thoracic; Barium; Benzyl Compounds; Cyclic AMP; Drug Antagonism; Drug Interactions; | 1972 |
[The positive ionotropic effect of dibutyryl-3',5'-AMP on isolated rat atria].
Topics: Animals; Atrial Function; Butyrates; Calcium; Cyclic AMP; Electric Stimulation; Epinephrine; Female; | 1972 |
Incorporation of the terminal phosphate of ATP into membranal protein of rabbit cardiac sarcoplasmic reticulum. Correlation with active calcium transport and study of the effects of cyclic AMP.
Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Calcium; Calcium Isotopes; Carbon Iso | 1972 |
Effect of catecholamines and angiotensin on cyclic AMP in rat aorta and tail artery.
Topics: Adenylyl Cyclases; Angiotensin II; Animals; Aorta; Arteries; Catecholamines; Cyclic AMP; Ethanol; In | 1971 |
Cholecystokinetic effect and concentration of cyclic AMP in gall-bladder muscle in vitro.
Topics: Animals; Cholecystokinin; Cyclic AMP; Female; Gallbladder; Guinea Pigs; Imidazoles; In Vitro Techniq | 1972 |
[3',5'-Adenosine monophosphate in the byssus retractor muscle of the mussel Mytilus edulis].
Topics: Acetylcholine; Animals; Bivalvia; Cyclic AMP; In Vitro Techniques; Muscle Contraction; Muscle Tonus; | 1972 |
Hormonal interactions in the uterus: inhibition of isoproterenol-induced accumulation of adenosine 3':5'-cyclic monophosphate by oxytocin and prostaglandins.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Drug Interactions; Endometrium; Female; Isoproterenol; Muscl | 1972 |
Effects of angiotensin II on cyclic 3'5'AMP in rat uterus.
Topics: Adenylyl Cyclases; Angiotensin II; Animals; Calcium; Carbon Isotopes; Chromatography, Ion Exchange; | 1972 |
Effect of cholecystokinin on the level of cyclic AMP and on mechanical activity in the isolated sphincter of Oddi.
Topics: Adenylyl Cyclases; Ampulla of Vater; Animals; Cats; Cholecystokinin; Cyclic AMP; Glucagon; Imidazole | 1972 |
Adenyl cyclase-phosphodiesterase system in arterial smooth muscle.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Aorta; Carbon Isotopes; Cyclic AMP; Dose-Respons | 1972 |
On the possible role of cyclic AMP in the neuromuscular transmission and in the treatment of myasthenia gravis.
Topics: Cyclic AMP; Humans; Muscle Contraction; Myasthenia Gravis; Papaverine; Stimulation, Chemical; Synapt | 1972 |
[Role of cyclic AMP in the mechanical activity of smooth muscle].
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Calcium; Catecholamines; Cell Membrane; Cyclic AMP; | 1973 |
Role of cyclic AMP and Ca++ in metabolic and mechanical events in smooth muscle.
Topics: Adenosine Triphosphate; Animals; Barium; Calcium; Calcium Isotopes; Carbachol; Colon; Corticosterone | 1972 |
Rat uterine contractility and the activities of uterine adenyl cyclase and phosphodiesterase during the estrus cycle.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Estrus; Female; In Vitro T | 1973 |
The effects of theophylline and cyclic AMP on intestinal smooth muscle contractions.
Topics: Animals; Colon; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle Contraction; | 1973 |
Effects of cyclic 3',5'-AMP and related compounds on catecholamine-induced contraction of isolated guinea-pig vas deferens.
Topics: Acetylcholine; Adenosine; Animals; Catecholamines; Cyclic AMP; Drug Synergism; Epinephrine; Guinea P | 1973 |
The effects of dibutyryl cyclic adenosine 3',5'-monophosphate, theophylline and aminophylline on neuromuscular transmission in the rat.
Topics: Action Potentials; Aminophylline; Animals; Binding Sites; Bucladesine; Diaphragm; Electric Stimulati | 1974 |
The influence of low and high doses of theophylline on spontaneous motility and cyclic 3',5' AMP content in isolated rat uterus.
Topics: Animals; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Muscle | 1974 |
[5-ht-induced relaxation and cyclic AMP in a molluscan smooth muscle (author's transl)].
Topics: Animals; Bivalvia; Calcium; Cyclic AMP; Cytosol; Muscle Contraction; Muscle, Smooth; Serotonin; Theo | 1974 |
Cyclic nucleotide levels during spontaneous uterine contractions.
Topics: Animals; Cyclic AMP; Cyclic GMP; Estrogens; Female; Isoproterenol; Muscle Contraction; Muscle, Smoot | 1974 |
The effects of epinephrine, prostaglandins, and their antagonists on adenosine cyclic 3',5'-monophosphate concentrations and motility of the rat uterus.
Topics: Adenine; Adenylyl Cyclases; Animals; Carbon Radioisotopes; Cyclic AMP; Dose-Response Relationship, D | 1974 |
Rabbit testicular capsular contractions--prostaglandins, cyclic adenosine 3',5'-monophosphate and epinephrine.
Topics: Adenosine; Animals; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Epine | 1974 |
The effect of theophylline on oxytocin induced contractions in the chronically catheterized pregnant rabbit.
Topics: Adrenocorticotropic Hormone; Animals; Catheterization; Female; Infusions, Parenteral; Muscle Contrac | 1974 |
Rat diaphragm cyclic nucleotide-phosphodiesterase: influence of drugs affecting skeletal muscle contractility.
Topics: Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Dialysis; Diaphragm; Hydrochlorothiazide; Hydrogen-Ion | 1974 |
Theophylline inhibition of nucleoside transport and its relation to cyclic AMP in skeletal muscle.
Topics: Adenine; Adenosine; Animals; Biological Transport; Bucladesine; Caffeine; Carbon Radioisotopes; Chro | 1974 |
Relation of c-amp to relaxation of pulmonary artery.
Topics: Animals; Cyclic AMP; Depression, Chemical; Epinephrine; Female; Isoproterenol; Muscle Contraction; M | 1974 |
Pharmacological reactivity of an isolated tracheal preparation of the guinea-pig.
Topics: Acetylcholine; Animals; Atropine; Barium; Chlorisondamine; Chlorpheniramine; Diphenhydramine; Ethano | 1966 |
Cardiac actions of glucagon.
Topics: Acetylcholine; Adenine Nucleotides; Animals; Blood Pressure; Calcium Chloride; Catecholamines; Cycli | 1968 |
[Pharmacological study of phenethyl-8-oxa-1-diaza-3,8-spiro(4,5)decanone-2 hydrochloride or fenspiride (JP 428)].
Topics: Anaphylaxis; Anesthesia; Animals; Anti-Inflammatory Agents; Atropine; Autonomic Nervous System; Bron | 1969 |
The inducement of tone and its inhibition in isolated tracheal muscle.
Topics: Animals; Atropine; Bronchodilator Agents; Epinephrine; Ethanol; Guinea Pigs; In Vitro Techniques; Is | 1971 |
Influence of caffeine and other methylxanthines on mechanical properties of isolated mammalian heart muscle. Evidence for a dual mechanism of action.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atropine; Caffeine; Calcium; Calcium Isotop | 1972 |
Topical differences of caffeine action on the smooth muscle cells of the guinea pig alimentary canal.
Topics: Adenosine Triphosphate; Animals; Caffeine; Digestive System; Female; Guinea Pigs; Ileum; In Vitro Te | 1974 |
Methylxanthine-induced escalation: a propagated wave phenomenon observed in skeletal muscle developing in culture.
Topics: Aminophylline; Animals; Calcium; Chick Embryo; Culture Techniques; Membrane Potentials; Microscopy, | 1972 |
A comparative description of inotropic agents in vitro.
Topics: Animals; Caffeine; Calcium; Cats; Cells, Cultured; Cocaine; Dose-Response Relationship, Drug; Glucag | 1973 |
The effect of quinidine bis-(7-theophyline acetate) on the isolated papillary muscle of the rabbit heart.
Topics: Action Potentials; Animals; Drug Combinations; In Vitro Techniques; Membrane Potentials; Muscle Cont | 1973 |
Effects of quazodine (MJ 1988) on contractions of the isolated hemidiaphragm of the rat and the biventer cervicis muscle of the chick.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Chickens; Diaphragm; Drug Synergism; Electric Stimulatio | 1973 |
Augmentation of the neural inhibitory response of the lower esophageal sphincter.
Topics: Acetylcholine; Animals; Dipyridamole; Electric Stimulation; Esophagus; Lidoflazine; Muscle Contracti | 1974 |
Effects of vasodilators on the isolated taenia coli of the guinea-pig.
Topics: Aminophylline; Animals; Calcium; Cell Membrane; Electrophysiology; Epinephrine; Guinea Pigs; In Vitr | 1967 |
[Pharmacological effects on the contraction frequency of isolated rat portal vein].
Topics: Aconitum; Animals; Atropine; Caffeine; Carbachol; Epinephrine; Histamine; In Vitro Techniques; Isopr | 1972 |
Mechanism of potentiation of contractor responses to catecholamines by methylxanthines in aortic strips.
Topics: Animals; Aorta; Caffeine; Catecholamines; Cycloparaffins; Drug Synergism; Epinephrine; In Vitro Tech | 1971 |
Elevation of guanosine 3',5'-cyclic phosphate in rat heart after perfusion with acetylcholine.
Topics: Acetylcholine; Animals; Guanine Nucleotides; Heart; Heart Rate; Isoproterenol; Male; Muscle Contract | 1970 |
The interaction of glucagon with theophylline, PGE1, isoproeerenol, ouabain, and CaC1 on the dog isolated papillary muscle.
Topics: Animals; Calcium Chloride; Dogs; Drug Synergism; Glucagon; In Vitro Techniques; Isoproterenol; Muscl | 1970 |
[Interaction between xanthines and noradrenaline- 3 H in the isolated rat heart].
Topics: Animals; Caffeine; Cardiac Output; Electrocardiography; Heart; Heart Rate; In Vitro Techniques; Male | 1970 |
Adrenergic receptors of the bovine iris sphincter.
Topics: Animals; Cattle; Drug Antagonism; In Vitro Techniques; Iris; Isoproterenol; Muscle Contraction; Phen | 1969 |
[Contractile function of the myocardium in experimental myocarditis].
Topics: Animals; Aorta; Epinephrine; Muscle Contraction; Myocarditis; Rabbits; Theophylline | 1965 |