theophylline has been researched along with Melanoma in 39 studies
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Culture of the human melanoma cell line MeWo in the presence of 1 mM theophylline was associated with an increase in susceptibility to natural killer (NK)-mediated cytolysis." | 7.67 | Enhanced natural killer sensitivity with concomitant clonal selection for cells bearing homogeneously staining regions in the human melanoma cell line MeWo upon induction of differentiation with theophylline. ( Haliotis, T; Holden, JJ; Liao, SK; Louwman, I; Matthews, J; Pross, HF; Riopelle, R; Smith, A; Werkmeister, JA; White, BN, 1984) |
| "The effect of theophylline, an inhibitor of phosphodiesterase, on tyrosine (Tyr) transport across cell membrane was studied using cultured B-16 mouse melanoma cells." | 7.67 | Effect of theophylline on the transport of tyrosine in cultured B-16 mouse melanoma cells. ( Saga, K; Shimojo, T, 1984) |
| "The effects of theophylline treatment on mouse B-16 melanoma cell growth, metabolism, and membrane antigen expression in vitro were studied." | 7.66 | Effects of theophylline treatment on mouse B-16 melanoma cells in vitro. ( Kolb, CA; Mansfield, JM, 1980) |
| " To gain a better understanding of this phenomenon, we studied the effects of theophylline on a cultured human malignant melanoma cell line (CaCL 73-36)." | 7.66 | Association of morphological differentiation with enhanced surface antigen expression and susceptibility to natural killer cell lysis in theophylline-treated human melanoma cells. ( Clark, DA; Dent, PB; Kwong, PC; Liao, SK; Smith, JW, 1983) |
| "The effects of theophylline and melanocyte-stimulating hormone on B16 melanoma cells in culture cells were studied by electron microscopy and dopa cytochemistry." | 7.66 | Electron microscopic and cytochemical observations of theophylline and melanocyte-stimulating hormone effects on melanoma cells in culture. ( Hu, F; Mah, K; Teramura, DJ, 1982) |
| "Two human malignant melanoma cell lines, differing in their patterns of HLA-DR antigen expression, were examined for changes in antigen expression following theophylline treatment." | 7.66 | Changes in HLA-DR antigen expression on cultured human melanoma cells during theophylline treatment. ( Dent, PB; Jerry, LM; Kwong, PC; Liao, SK, 1982) |
| " Linear uptake of tyrosine lasted for 1 min in cultured B-16 mouse melanoma cells preloaded with an amino acid such as tyrosine." | 7.66 | Studies on the transport of tyrosine, leucine, and methionine in cultured B-16 mouse melanoma cells. ( Saga, K; Shimojo, T, 1982) |
| "The combination of MSH and theophylline is synergistic in inhibiting the growth as well as stimulating the differentiation of pigmented melanoma cells." | 7.66 | Inhibition of clonogenic growth of melanoma cells by combination of melanocyte stimulating hormone and theophylline. ( Wick, MM, 1981) |
| "We have studied the effects of theophylline treatment on pigmentation characteristics and growth of two B16 melanoma cell lines, HFH-18 and P/140." | 7.66 | Tyrosinase maturation and pigment expression in B16 melanoma: relation to theophylline treatment and intracellular cyclic AMP. ( Hanson, GC; White, R, 1979) |
| "Cutaneous melanoma is the most aggressive skin cancer, derived from neoplastic transformation of melanocytes." | 5.51 | Theophylline induces differentiation and modulates cytoskeleton dynamics and cytokines secretion in human melanoma-initiating cells. ( Cordella, M; D'Arcangelo, D; Eramo, A; Facchiano, A; Facchiano, F; Lintas, C; Mueller, S; Rossi, S; Senatore, C; Tabolacci, C; Valitutti, S, 2019) |
| "The rationale for melanoma-specific antitumor agents containing phenolic amines is based in part on the ability of the enzyme tyrosinase to oxidize these prodrugs to toxic intermediates." | 5.28 | Thymidylate synthase as a target enzyme for the melanoma-specific toxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol. ( Bloomer, WD; Prezioso, JA; Wang, N, 1992) |
| "The methanolic extract from the flower buds of Prunus mume, cultivated in Zhejiang Province, China, showed an inhibitory effect on melanogenesis in theophylline-stimulated B16 melanoma 4A5 cells." | 3.79 | Acylated sucroses and acylated quinic acids analogs from the flower buds of Prunus mume and their inhibitory effect on melanogenesis. ( Fujimoto, K; Matsuda, H; Matsumoto, T; Nakamura, S; Nakashima, S; Ogawa, K; Ohta, T; Yoshikawa, M, 2013) |
| "Culture of the human melanoma cell line MeWo in the presence of 1 mM theophylline was associated with an increase in susceptibility to natural killer (NK)-mediated cytolysis." | 3.67 | Enhanced natural killer sensitivity with concomitant clonal selection for cells bearing homogeneously staining regions in the human melanoma cell line MeWo upon induction of differentiation with theophylline. ( Haliotis, T; Holden, JJ; Liao, SK; Louwman, I; Matthews, J; Pross, HF; Riopelle, R; Smith, A; Werkmeister, JA; White, BN, 1984) |
| "The effect of theophylline, an inhibitor of phosphodiesterase, on tyrosine (Tyr) transport across cell membrane was studied using cultured B-16 mouse melanoma cells." | 3.67 | Effect of theophylline on the transport of tyrosine in cultured B-16 mouse melanoma cells. ( Saga, K; Shimojo, T, 1984) |
| "The anti-tumour methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide (MTIC) increased the thymidine and deoxycytidine pools but not the deoxyguanosine pool in human melanoma cells." | 3.67 | Epigenetic effects of the methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide in human melanoma cells. ( Hayward, IP; Parsons, PG, 1984) |
| "The effects of theophylline treatment on mouse B-16 melanoma cell growth, metabolism, and membrane antigen expression in vitro were studied." | 3.66 | Effects of theophylline treatment on mouse B-16 melanoma cells in vitro. ( Kolb, CA; Mansfield, JM, 1980) |
| " To gain a better understanding of this phenomenon, we studied the effects of theophylline on a cultured human malignant melanoma cell line (CaCL 73-36)." | 3.66 | Association of morphological differentiation with enhanced surface antigen expression and susceptibility to natural killer cell lysis in theophylline-treated human melanoma cells. ( Clark, DA; Dent, PB; Kwong, PC; Liao, SK; Smith, JW, 1983) |
| "The effects of theophylline and melanocyte-stimulating hormone on B16 melanoma cells in culture cells were studied by electron microscopy and dopa cytochemistry." | 3.66 | Electron microscopic and cytochemical observations of theophylline and melanocyte-stimulating hormone effects on melanoma cells in culture. ( Hu, F; Mah, K; Teramura, DJ, 1982) |
| "Two human malignant melanoma cell lines, differing in their patterns of HLA-DR antigen expression, were examined for changes in antigen expression following theophylline treatment." | 3.66 | Changes in HLA-DR antigen expression on cultured human melanoma cells during theophylline treatment. ( Dent, PB; Jerry, LM; Kwong, PC; Liao, SK, 1982) |
| " Linear uptake of tyrosine lasted for 1 min in cultured B-16 mouse melanoma cells preloaded with an amino acid such as tyrosine." | 3.66 | Studies on the transport of tyrosine, leucine, and methionine in cultured B-16 mouse melanoma cells. ( Saga, K; Shimojo, T, 1982) |
| "The combination of MSH and theophylline is synergistic in inhibiting the growth as well as stimulating the differentiation of pigmented melanoma cells." | 3.66 | Inhibition of clonogenic growth of melanoma cells by combination of melanocyte stimulating hormone and theophylline. ( Wick, MM, 1981) |
| "Sodium butyrate and cyclic AMP-stimulating agents (prostaglandin E1, papaverine, theophylline, and RO20-1724) caused reductions in the cell number (primarily due to reduction in cell division) when added individually to human melanoma cells in culture." | 3.66 | Effect of sodium butyrate in combination with prostaglandin E1 and inhibitors of cyclic nucleotide phosphodiesterase on human amelanotic melanoma cells in culture. ( Prasad, KN; Sakamoto, A, 1978) |
| "We have studied the effects of theophylline treatment on pigmentation characteristics and growth of two B16 melanoma cell lines, HFH-18 and P/140." | 3.66 | Tyrosinase maturation and pigment expression in B16 melanoma: relation to theophylline treatment and intracellular cyclic AMP. ( Hanson, GC; White, R, 1979) |
| "Cultured Cloudman melanoma cells exposed either to dibutyryl 3':5'-cyclic AMP and theophylline or to cholera toxin bind significantly more 125I-labeled beta-melanocyte stimulating hormone (MSH) and fluorescein-labeled MSH than untreated cells." | 3.65 | The number of receptors for beta-melanocyte stimulating hormone in Cloudman melanoma cells is increased by dibutyryl adenosine 3':5'-cyclic monophosphate or cholera toxin. ( DiPasquale, A; McGuire, J; Varga, JM, 1977) |
| "Cutaneous melanoma is the most aggressive skin cancer, derived from neoplastic transformation of melanocytes." | 1.51 | Theophylline induces differentiation and modulates cytoskeleton dynamics and cytokines secretion in human melanoma-initiating cells. ( Cordella, M; D'Arcangelo, D; Eramo, A; Facchiano, A; Facchiano, F; Lintas, C; Mueller, S; Rossi, S; Senatore, C; Tabolacci, C; Valitutti, S, 2019) |
| " In this study, we established a melanogenesis regulation assay system using a fluorescent protein reporter combined with the promoters for the microphthalmia-associated transcription factor (MITF), tyrosinase (Tyr) and dopachrome tautomerase (Dct) genes in MeWo human melanoma cells." | 1.42 | Establishment of a melanogenesis regulation assay system using a fluorescent protein reporter combined with the promoters for the melanogenesis-related genes in human melanoma cells. ( Chen, CY; Chiu, YW; Lin, CC; Lin, YJ; Yang, CH, 2015) |
| "The rationale for melanoma-specific antitumor agents containing phenolic amines is based in part on the ability of the enzyme tyrosinase to oxidize these prodrugs to toxic intermediates." | 1.28 | Thymidylate synthase as a target enzyme for the melanoma-specific toxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol. ( Bloomer, WD; Prezioso, JA; Wang, N, 1992) |
| "Theophylline was the most effective stimulator of tyrosinase in melanoma-derived cell populations and caused increased enzyme activity in eight of eleven cell lines." | 1.26 | Endocrine responsiveness in human melanocytes and melanoma cells in culture. ( Fuller, BB; Meyskens, FL, 1981) |
| "Metastasis is the principal cause of failures to cure human cancers." | 1.26 | Prostacyclin: a potent antimetastatic agent. ( Cicone, B; Honn, KV; Skoff, A, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (79.49) | 18.7374 |
| 1990's | 3 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (12.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cordella, M | 1 |
| Tabolacci, C | 2 |
| Senatore, C | 1 |
| Rossi, S | 1 |
| Mueller, S | 1 |
| Lintas, C | 1 |
| Eramo, A | 1 |
| D'Arcangelo, D | 1 |
| Valitutti, S | 1 |
| Facchiano, A | 1 |
| Facchiano, F | 1 |
| Nakamura, S | 2 |
| Fujimoto, K | 1 |
| Matsumoto, T | 1 |
| Nakashima, S | 1 |
| Ohta, T | 1 |
| Ogawa, K | 1 |
| Matsuda, H | 1 |
| Yoshikawa, M | 1 |
| Lin, CC | 1 |
| Yang, CH | 1 |
| Lin, YJ | 1 |
| Chiu, YW | 1 |
| Chen, CY | 1 |
| Katsuyama, Y | 1 |
| Taira, N | 1 |
| Yoshioka, M | 1 |
| Okano, Y | 1 |
| Masaki, H | 1 |
| Lentini, A | 1 |
| Nardi, A | 1 |
| Mattioli, P | 1 |
| Provenzano, B | 1 |
| Beninati, S | 1 |
| Hu, F | 2 |
| Haliotis, T | 2 |
| Werkmeister, JA | 1 |
| Louwman, I | 1 |
| Liao, SK | 4 |
| Matthews, J | 1 |
| Riopelle, R | 1 |
| Pross, HF | 1 |
| Holden, JJ | 1 |
| White, BN | 1 |
| Smith, A | 1 |
| Kimura, M | 1 |
| Nishihira, T | 1 |
| Kasai, M | 1 |
| Sato, H | 1 |
| Fuller, BB | 3 |
| Lebowitz, J | 1 |
| Kolb, CA | 1 |
| Mansfield, JM | 1 |
| Montefiori, DC | 1 |
| Kline, EL | 1 |
| Meyskens, FL | 1 |
| Negishi, S | 1 |
| Masada, M | 1 |
| Wakamatsu, Y | 1 |
| Ohoka, T | 1 |
| Obika, M | 1 |
| Riopelle, RJ | 1 |
| Roder, JC | 1 |
| Blagoeva, PM | 1 |
| Balansky, RM | 1 |
| Karpatkin, S | 1 |
| Ambrogio, C | 1 |
| Pearlstein, E | 1 |
| Saga, K | 2 |
| Shimojo, T | 2 |
| Hayward, IP | 1 |
| Parsons, PG | 1 |
| Kwong, PC | 2 |
| Smith, JW | 2 |
| Dent, PB | 2 |
| Clark, DA | 1 |
| Mah, K | 1 |
| Teramura, DJ | 1 |
| Jerry, LM | 1 |
| Honn, KV | 1 |
| Cicone, B | 1 |
| Skoff, A | 1 |
| Wick, MM | 2 |
| Jiang, J | 1 |
| Sharma, SD | 1 |
| Lai, JY | 1 |
| Fink, JL | 1 |
| Hruby, VJ | 1 |
| Hadley, ME | 1 |
| Kreider, JW | 2 |
| Wade, DR | 1 |
| Rosenthal, M | 2 |
| Densley, T | 1 |
| DiPasquale, A | 1 |
| McGuire, J | 1 |
| Varga, JM | 1 |
| Steinberg, ML | 1 |
| Whittaker, JR | 1 |
| Prasad, KN | 1 |
| Sakamoto, A | 1 |
| White, R | 1 |
| Hanson, GC | 1 |
| Viskochil, DH | 1 |
| Frei, E | 1 |
| Prezioso, JA | 2 |
| Wang, N | 2 |
| Bloomer, WD | 2 |
| Epperly, MW | 1 |
| Kwon, BS | 1 |
| Halaban, R | 1 |
| Kim, GS | 1 |
| Usack, L | 1 |
| Pomerantz, S | 1 |
| Haq, AK | 1 |
| Noga, EJ | 1 |
| Barthalmus, GT | 1 |
| Mitchell, MK | 1 |
| Lochmanová, A | 1 |
| Borysová, L | 1 |
| Lochman, I | 1 |
| Kawakubo, Y | 1 |
| Singal, DP | 1 |
| Wong, YH | 1 |
| Lengle, N | 1 |
39 other studies available for theophylline and Melanoma
| Article | Year |
|---|---|
Theophylline induces differentiation and modulates cytoskeleton dynamics and cytokines secretion in human melanoma-initiating cells.
Topics: Apoptosis; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cytokines; Cyt | 2019 |
Acylated sucroses and acylated quinic acids analogs from the flower buds of Prunus mume and their inhibitory effect on melanogenesis.
Topics: Acylation; Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Dose-Response Relationship, Dr | 2013 |
Establishment of a melanogenesis regulation assay system using a fluorescent protein reporter combined with the promoters for the melanogenesis-related genes in human melanoma cells.
Topics: Acetophenones; Arbutin; Benzopyrans; Cell Line, Tumor; Drug Evaluation, Preclinical; Enzyme Inductio | 2015 |
Disruption of melanosome transport in melanocytes treated with theophylline causes their degradation by autophagy.
Topics: Animals; Autophagy; Biological Transport; Cell Line, Tumor; Gene Expression Regulation; Gene Knockdo | 2017 |
Preclinical evaluation of the antineoplastic efficacy of 7-(2-hydroxyethyl)theophylline on melanoma cancer cells.
Topics: Animals; Antineoplastic Agents; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Drug Screening | 2012 |
Theophylline and melanocyte-stimulating hormone effects on gamma-glutamyl transpeptidase and DOPA reactions in cultured melanoma cells.
Topics: Animals; Cell Line; Dihydroxyphenylalanine; gamma-Glutamyltransferase; Melanocyte-Stimulating Hormon | 1982 |
Enhanced natural killer sensitivity with concomitant clonal selection for cells bearing homogeneously staining regions in the human melanoma cell line MeWo upon induction of differentiation with theophylline.
Topics: Cell Cycle; Cell Differentiation; Cell Line; Clone Cells; Cytotoxicity, Immunologic; Flow Cytometry; | 1984 |
Differentiative and proliferative effects of (But)2cAMP, n-butyric acid and prednisolone on the malignant melanoma cell line (TM-1) in vitro and in vivo.
Topics: Animals; Bucladesine; Butyrates; Cell Differentiation; Cell Division; Cell Line; Melanoma; Mice; Neo | 1980 |
Decay of hormone responsiveness in mouse melanoma cells in culture as a function of cell density.
Topics: Animals; Bucladesine; Catechol Oxidase; Cell Count; Cells, Cultured; Cyclic AMP; Dose-Response Relat | 1980 |
Effects of theophylline treatment on mouse B-16 melanoma cells in vitro.
Topics: Animals; Antigens, Neoplasm; Cell Cycle; Cell Division; Cell Survival; Cells, Cultured; Cyclic AMP; | 1980 |
Regulation of cell division and of tyrosinase in B16 melanoma cells by imidazole: a possible role for the concept of metabolite gene regulation in mammalian cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Catechol Oxidase; Cell Division; Cyclic AMP; Cyclohexi | 1981 |
Endocrine responsiveness in human melanocytes and melanoma cells in culture.
Topics: Bucladesine; Catechol Oxidase; Cell Differentiation; Cell Line; Humans; Melanocyte-Stimulating Hormo | 1981 |
Epinephrine-induced changes in the cyclic nucleotide content of fish melanoma cells.
Topics: Animals; Cells, Cultured; Cyclic AMP; Cyclic GMP; Epinephrine; Fishes; Melanocytes; Melanoma; Melano | 1982 |
Nerve growth factor receptors of human tumors of neural crest origin: characterization of binding site heterogeneity and alteration by theophylline.
Topics: Animals; Cell Cycle; Cell Line; Humans; Kinetics; Male; Melanoma; Mice; Nerve Growth Factors; Neural | 1983 |
Effect of theophyllin and isoproterenol on cAMP level in melanotic and amelanotic hamster melanomas.
Topics: Animals; Cell Differentiation; Cricetinae; Cyclic AMP; Isoproterenol; Male; Melanoma; Mesocricetus; | 1983 |
Lack of effect of in vivo prostacyclin on the development of pulmonary metastases in mice following intravenous injection of CT26 colon carcinoma, Lewis lung carcinoma, or B16 amelanotic melanoma cells.
Topics: Animals; Cell Line; Colonic Neoplasms; Epoprostenol; Lung Neoplasms; Melanoma; Mice; Platelet Aggreg | 1984 |
Effect of theophylline on the transport of tyrosine in cultured B-16 mouse melanoma cells.
Topics: Animals; Biological Transport, Active; Cell Count; Cell Line; Cells, Cultured; Cycloheximide; Melano | 1984 |
Epigenetic effects of the methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide in human melanoma cells.
Topics: Alkylating Agents; Antineoplastic Agents; Cell Line; Dacarbazine; Deoxycytidine; Deoxyguanosine; Gen | 1984 |
Association of morphological differentiation with enhanced surface antigen expression and susceptibility to natural killer cell lysis in theophylline-treated human melanoma cells.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Cell Differentiation; Cell Line; Hema | 1983 |
Electron microscopic and cytochemical observations of theophylline and melanocyte-stimulating hormone effects on melanoma cells in culture.
Topics: Animals; Cell Line; Cells, Cultured; Dihydroxyphenylalanine; Melanocyte-Stimulating Hormones; Melano | 1982 |
Changes in HLA-DR antigen expression on cultured human melanoma cells during theophylline treatment.
Topics: Animals; Antilymphocyte Serum; Cell Line; Cell Transformation, Neoplastic; Histocompatibility Antige | 1982 |
Prostacyclin: a potent antimetastatic agent.
Topics: Animals; Antineoplastic Agents; Epoprostenol; Lung Neoplasms; Melanoma; Mice; Neoplasm Metastasis; N | 1981 |
Studies on the transport of tyrosine, leucine, and methionine in cultured B-16 mouse melanoma cells.
Topics: Animals; Cells, Cultured; Kinetics; Leucine; Melanoma; Methionine; Mice; Neoplasms, Experimental; So | 1982 |
Inhibition of clonogenic growth of melanoma cells by combination of melanocyte stimulating hormone and theophylline.
Topics: Animals; Cell Division; Cells, Cultured; Clone Cells; Colony-Forming Units Assay; Cricetinae; Cricet | 1981 |
The melanotropic peptide, [Nle4,D-Phe7] alpha-MSH, stimulates human melanoma tyrosinase activity and inhibits cell proliferation.
Topics: alpha-MSH; Animals; Cell Division; Cyclic AMP; Humans; Melanoma; Mice; Monophenol Monooxygenase; Pho | 1995 |
Maturation and differentiation of B16 melanoma cells induced by theophylline treatment.
Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Clone Cells; Cyclic AMP; DNA, Neoplas | 1975 |
The number of receptors for beta-melanocyte stimulating hormone in Cloudman melanoma cells is increased by dibutyryl adenosine 3':5'-cyclic monophosphate or cholera toxin.
Topics: Bacterial Toxins; Bucladesine; Cell Line; Kinetics; Melanocyte-Stimulating Hormones; Melanoma; Recep | 1977 |
Theophylline incorporation into the nucleic acids of theophylline-stimulated melanoma cells.
Topics: Animals; Bucladesine; Cricetinae; Cyclic AMP; DNA, Neoplasm; Melanins; Melanoma; Neoplasms, Experime | 1978 |
Effect of sodium butyrate in combination with prostaglandin E1 and inhibitors of cyclic nucleotide phosphodiesterase on human amelanotic melanoma cells in culture.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Butyrates; Cell | 1978 |
Tyrosinase maturation and pigment expression in B16 melanoma: relation to theophylline treatment and intracellular cyclic AMP.
Topics: Animals; Catechol Oxidase; Cell Division; Cell Line; Cyclic AMP; Enzyme Induction; Kinetics; Melanom | 1979 |
The role of RNA and protein synthesis in mediating the action of MSH on mouse melanoma cells.
Topics: Animals; Antineoplastic Agents; Bucladesine; Cells, Cultured; Cyclic AMP; Melanocyte-Stimulating Hor | 1979 |
Selective incorporation of L-3,4-dihydroxyphenylalanine by S-91 Cloudman melanoma in vitro.
Topics: Cells, Cultured; Cycloheximide; Levodopa; Melanins; Melanocyte-Stimulating Hormones; Melanoma; Neopl | 1977 |
Thymidylate synthase as a target enzyme for the melanoma-specific toxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol.
Topics: Antineoplastic Agents; Cell Division; Cell-Free System; Cysteamine; DNA; Humans; Kinetics; Leucovori | 1992 |
Effects of tyrosinase activity on the cytotoxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol in melanoma cells.
Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Division; Cysteamine; Drug Synergism; Humans; Me | 1992 |
A melanocyte-specific complementary DNA clone whose expression is inducible by melanotropin and isobutylmethyl xanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antibodies, Monoclonal; Catechol Oxidase; DNA; Gene Expression | 1987 |
Cyclic amines are selective cytotoxic agents for pigmented cells.
Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; Drug Synergism; Melanins; Melanoma; Mice; Morph | 1986 |
[The effect of histamine and theophylline and the formation of E rosettes].
Topics: Asthma; Histamine; Humans; Melanoma; Rhinitis, Allergic, Seasonal; Rosette Formation; Theophylline | 1986 |
Extent of morphological differentiation of human melanoma cells reflected by HLA-DR antigen profiles.
Topics: Bromodeoxyuridine; Cell Line; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Killer | 1985 |
Cyclic adenosine 3',5'-monophosphate in the control of melanoma cell replication and differentiation.
Topics: Caffeine; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cyc | 1973 |