theophylline has been researched along with Lung Neoplasms in 37 studies
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The current experiment has tested the hypothesis that green tea and the methylxanthine theophylline contained in tea inhibit the progression of neuroendocrine lung carcinogenesis in hamsters with hyperoxic lung injury and initiated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) while promoting the development of Clara cell-derived pulmonary adenocarcinomas initiated by NNK in healthy hamsters." | 7.72 | Neuroendocrine lung carcinogenesis in hamsters is inhibited by green tea or theophylline while the development of adenocarcinomas is promoted: implications for chemoprevention in smokers. ( Porter, B; Riechert, A; Schmoyer, R; Schuller, HM; Walker, K, 2004) |
| "Theophylline was absorbed rapidly in all subjects and within 2 h reached comparable peak concentrations in both groups (cancer patients: 57." | 6.67 | The disposition of theophylline in patients with lung and breast cancer. ( Attardo-Parrinello, G; Barzaghi, N; Corasaniti, MT; Crema, F; Gatti, G; Perucca, E, 1994) |
| " The current experiment has tested the hypothesis that green tea and the methylxanthine theophylline contained in tea inhibit the progression of neuroendocrine lung carcinogenesis in hamsters with hyperoxic lung injury and initiated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) while promoting the development of Clara cell-derived pulmonary adenocarcinomas initiated by NNK in healthy hamsters." | 3.72 | Neuroendocrine lung carcinogenesis in hamsters is inhibited by green tea or theophylline while the development of adenocarcinomas is promoted: implications for chemoprevention in smokers. ( Porter, B; Riechert, A; Schmoyer, R; Schuller, HM; Walker, K, 2004) |
| "Comparative investigation of subpopulations and functional properties of lymphocytes isolated from the tumour tissue (TTL) as well as of lymphocytes of the peripheral blood (PBL) of 11 lung cancer patients and 18 breast cancer patients has shown that an increase in the quantity of theophylline-sensitive cells (suppressors and killers) is characteristic of TTL." | 3.67 | [Comparative study of the lymphocyte surface receptors isolated from the blood and tissue of malignant tumors]. ( Bilynskiĭ, BT; Volod'ko, NA, 1986) |
| "Theophylline was absorbed rapidly in all subjects and within 2 h reached comparable peak concentrations in both groups (cancer patients: 57." | 2.67 | The disposition of theophylline in patients with lung and breast cancer. ( Attardo-Parrinello, G; Barzaghi, N; Corasaniti, MT; Crema, F; Gatti, G; Perucca, E, 1994) |
| "Lung cancer is the leading cause of cancer death in industrialized countries." | 1.31 | Beta-adrenergic modulation of NNK-induced lung carcinogenesis in hamsters. ( Porter, B; Riechert, A; Schuller, HM, 2000) |
| "Theophylline-treated B16-F10 melanoma cells show a lower experimental metastatic potential in vivo." | 1.31 | Theophylline administration markedly reduces hepatic and pulmonary implantation of B16-F10 melanoma cells in mice. ( Abbruzzese, A; Beninati, S; Caraglia, M; Facchiano, F; Lentini, A; Vidal-Vanaclocha, F, 2000) |
| "Pre-treatment with motapizone, RP73401, rolipram or the methylxanthine adenosine receptor antagonist, 8-phenyltheophylline, did not significantly decrease responses to either allergen or LTC(4)." | 1.31 | The effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C(4)-induced contractions in passively sensitized human airways. ( Branscheid, D; Dent, G; Magnussen, H; Rabe, KF; Rühlmann, E; Schmidt, DT; Watson, N, 2000) |
| "Theophylline- and caffeine-treated B16-F10 cells exhibited low adhesion to laminin/collagen type IV and reduced invasion through Matrigel in an in vitro assay." | 1.30 | Inhibition of melanoma pulmonary metastasis by methylxanthines due to decreased invasion and proliferation. ( Abbruzzese, A; Autuori-Pezzoli, V; Beninati, S; Cardinali, M; Kleinman, HK; Lentini, A; Mattioli, P; Nicolini, L; Pietrini, A, 1998) |
| "The analysis of 178 cases of stage I-II breast cancer showed morphological features of local cell-mediated immune reactions to be of limited prognostic value." | 1.27 | [Local cellular immune reactions in cancer patients]. ( Bilynskiĭ, BT; Vasil'ev, NV; Volod'ko, NA, 1988) |
| "Metastasis is the principal cause of failures to cure human cancers." | 1.26 | Prostacyclin: a potent antimetastatic agent. ( Cicone, B; Honn, KV; Skoff, A, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (54.05) | 18.7374 |
| 1990's | 5 (13.51) | 18.2507 |
| 2000's | 8 (21.62) | 29.6817 |
| 2010's | 2 (5.41) | 24.3611 |
| 2020's | 2 (5.41) | 2.80 |
| Authors | Studies |
|---|---|
| Shahzadi, I | 1 |
| Parveen, B | 1 |
| Ahmad, S | 1 |
| Gul Khan, S | 1 |
| Zahoor, AF | 1 |
| Rasul, A | 1 |
| Zahid, FM | 1 |
| Eguchi, H | 1 |
| Kimura, R | 1 |
| Onuma, S | 1 |
| Ito, A | 1 |
| Yu, Y | 1 |
| Yoshino, Y | 1 |
| Matsunaga, T | 1 |
| Endo, S | 1 |
| Ikari, A | 1 |
| Zhang, Y | 1 |
| Wang, J | 1 |
| Cheng, H | 1 |
| Sun, Y | 1 |
| Liu, M | 1 |
| Wu, Z | 1 |
| Pei, R | 1 |
| Lentini, A | 3 |
| Tabolacci, C | 1 |
| Mattioli, P | 2 |
| Provenzano, B | 1 |
| Beninati, S | 3 |
| BRENNIG, K | 1 |
| HAGIWARA, T | 1 |
| OKAYASU, D | 1 |
| NAKAJIMA, S | 1 |
| NISHIJIMA, T | 1 |
| HEULIN, A | 1 |
| SORS, C | 1 |
| Schuller, HM | 3 |
| Porter, B | 2 |
| Riechert, A | 2 |
| Walker, K | 1 |
| Schmoyer, R | 1 |
| Hirsh, L | 2 |
| Dantes, A | 2 |
| Suh, BS | 2 |
| Yoshida, Y | 1 |
| Hosokawa, K | 1 |
| Tajima, K | 1 |
| Kotsuji, F | 1 |
| Merimsky, O | 2 |
| Amsterdam, A | 2 |
| Land-Bracha, A | 1 |
| Hussein, A | 1 |
| Al-Wadei, N | 1 |
| Takahashi, T | 2 |
| Malki, AM | 1 |
| Gentry, J | 1 |
| Evans, SC | 1 |
| Janik, P | 1 |
| Assaf, A | 1 |
| Bertram, JS | 1 |
| Flenley, DC | 1 |
| Karpatkin, S | 1 |
| Ambrogio, C | 1 |
| Pearlstein, E | 1 |
| Hainaut, J | 1 |
| Devismes, D | 1 |
| Nomura, T | 1 |
| Honn, KV | 1 |
| Cicone, B | 1 |
| Skoff, A | 1 |
| Corasaniti, MT | 1 |
| Gatti, G | 1 |
| Crema, F | 1 |
| Attardo-Parrinello, G | 1 |
| Barzaghi, N | 1 |
| Perucca, E | 1 |
| Entzian, P | 1 |
| Barth, J | 1 |
| Kodama, H | 1 |
| Yoshida, I | 1 |
| Ishikawa, S | 1 |
| Ohtaki, A | 1 |
| Satoh, Y | 1 |
| Kawashima, O | 1 |
| Morishita, Y | 1 |
| Kleinman, HK | 1 |
| Autuori-Pezzoli, V | 1 |
| Nicolini, L | 1 |
| Pietrini, A | 1 |
| Abbruzzese, A | 2 |
| Cardinali, M | 1 |
| Vidal-Vanaclocha, F | 1 |
| Facchiano, F | 1 |
| Caraglia, M | 1 |
| Schmidt, DT | 1 |
| Watson, N | 1 |
| Dent, G | 1 |
| Rühlmann, E | 1 |
| Branscheid, D | 1 |
| Magnussen, H | 1 |
| Rabe, KF | 1 |
| Curtis-Prior, PB | 1 |
| Gibbons, JR | 1 |
| Chan, YH | 1 |
| Giaccone, G | 1 |
| Broers, J | 1 |
| Jensen, S | 1 |
| Fridman, RI | 1 |
| Linnoila, R | 1 |
| Gazdar, AF | 2 |
| Skillrud, DM | 1 |
| Moody, TW | 2 |
| Carney, DN | 2 |
| Korman, LY | 2 |
| Minna, JD | 1 |
| Citron, ML | 1 |
| Bilynskiĭ, BT | 2 |
| Vasil'ev, NV | 1 |
| Volod'ko, NA | 2 |
| Mosienko, MD | 1 |
| Dorfman, MV | 1 |
| Romashko, NI | 1 |
| Wolberg, WH | 1 |
| Williams, MH | 1 |
| Güttner, J | 1 |
| Horn, M | 1 |
| Jungstand, W | 1 |
| Malmberg, R | 1 |
2 reviews available for theophylline and Lung Neoplasms
| Article | Year |
|---|---|
[THERAPY OF CHRONIC BRONCHITIS].
Topics: Aerosols; Air Pollution; Analgesics; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Antipyretics; | 1964 |
Recent advances in respiratory medicine.
Topics: Adult; Aged; Anti-Bacterial Agents; Asthma; Bronchitis; Cephalosporins; Child; Humans; Immunosuppres | 1983 |
1 trial available for theophylline and Lung Neoplasms
| Article | Year |
|---|---|
The disposition of theophylline in patients with lung and breast cancer.
Topics: Adult; Biotransformation; Breast Neoplasms; Female; Half-Life; Humans; Immunoenzyme Techniques; Inte | 1994 |
34 other studies available for theophylline and Lung Neoplasms
| Article | Year |
|---|---|
In-vitro cytotoxic evaluation, hemolytic and thrombolytic potential of newly designed acefylline based hydrazones as potent anticancer agents against human lung cancer cell line (A549).
Topics: Antineoplastic Agents; Cell Line, Tumor; Hemolysis; Humans; Hydrazones; Lung Neoplasms; Structure-Ac | 2022 |
Elevation of Anticancer Drug Toxicity by Caffeine in Spheroid Model of Human Lung Adenocarcinoma A549 Cells Mediated by Reduction in Claudin-2 and Nrf2 Expression.
Topics: A549 Cells; Adenocarcinoma of Lung; Antineoplastic Agents; Caffeine; Claudin-2; Doxorubicin; Humans; | 2022 |
Conditional control of suicide gene expression in tumor cells with theophylline-responsive ribozyme.
Topics: A549 Cells; Bronchodilator Agents; Gene Expression Regulation, Enzymologic; Genes, Transgenic, Suici | 2017 |
Antitumor activity of theophylline in combination with Paclitaxel: a preclinical study on melanoma experimental lung metastasis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cell Pro | 2010 |
[CLINICAL STUDIES WITH VOYAL IN RADIATION INJURIES].
Topics: Breast Neoplasms; Diphenhydramine; Female; Humans; Lung Neoplasms; Radiation Injuries; Theophylline; | 1963 |
[CLINICAL STUDY OF A EUPNEIC AGENT: AMPLIPHYLLINE].
Topics: Asthma; Bronchiectasis; Bronchitis; Bronchodilator Agents; Dyspnea; Dyspnea, Paroxysmal; Humans; Lun | 1964 |
Neuroendocrine lung carcinogenesis in hamsters is inhibited by green tea or theophylline while the development of adenocarcinomas is promoted: implications for chemoprevention in smokers.
Topics: Adenocarcinoma; Animals; Bronchodilator Agents; Cell Transformation, Neoplastic; Chemoprevention; Cr | 2004 |
Phosphodiesterase inhibitors as anti-cancer drugs.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Division; Drug Synergism; Female; Humans; Lung Neopl | 2004 |
Induction of apoptosis in non-small lung carcinoma cell line (H1299) by combination of anti-asthma drugs with gemcitabine and cisplatin.
Topics: Anti-Asthmatic Agents; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumo | 2005 |
Theophylline stimulates cAMP-mediated signaling associated with growth regulation in human cells from pulmonary adenocarcinoma and small airway epithelia.
Topics: Adenocarcinoma; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Colforsin; Criceti | 2005 |
Differential effect of selected methylxanthine derivatives on radiosensitization of lung carcinoma cells.
Topics: Apoptosis; Caffeine; Carcinoma, Large Cell; Cell Line, Tumor; Cell Survival; Flow Cytometry; Gamma R | 2006 |
Inhibition of growth of primary and metastatic Lewis lung carcinoma cells by the phosphodiesterase inhibitor isobutylmethylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Division; Female; Lung Neoplasms; Male; Mice; Neoplasm Me | 1980 |
Lack of effect of in vivo prostacyclin on the development of pulmonary metastases in mice following intravenous injection of CT26 colon carcinoma, Lewis lung carcinoma, or B16 amelanotic melanoma cells.
Topics: Animals; Cell Line; Colonic Neoplasms; Epoprostenol; Lung Neoplasms; Melanoma; Mice; Platelet Aggreg | 1984 |
[Increase by the total dialysate leukocyte extract of E rosette formation in human theophylline treated lymphocytes].
Topics: Humans; Leukocytes; Lung Neoplasms; Lymphocytes; Rosette Formation; Theophylline; Tissue Extracts | 1980 |
Comparative inhibiting effects of methylxanthines on urethan-induced tumors, malformations, and presumed somatic mutations in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Caffeine; DNA Repair; Lung Neoplasms; M | 1983 |
Prostacyclin: a potent antimetastatic agent.
Topics: Animals; Antineoplastic Agents; Epoprostenol; Lung Neoplasms; Melanoma; Mice; Neoplasm Metastasis; N | 1981 |
[Diagnostic errors in dyspnea].
Topics: Adenocarcinoma, Mucinous; Adult; alpha 1-Antitrypsin Deficiency; Diagnostic Errors; Dyspnea; Heart F | 1993 |
[Thoracotomy for patients with bronchial asthma].
Topics: Adult; Aminophylline; Anesthetics, Inhalation; Asthma; Blister; Bronchodilator Agents; Female; Human | 1994 |
Inhibition of melanoma pulmonary metastasis by methylxanthines due to decreased invasion and proliferation.
Topics: Animals; Caffeine; Cell Adhesion; Cell Division; Collagen; Laminin; Lung Neoplasms; Male; Melanins; | 1998 |
Beta-adrenergic modulation of NNK-induced lung carcinogenesis in hamsters.
Topics: Adenocarcinoma; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carcinogens; Criceti | 2000 |
Theophylline administration markedly reduces hepatic and pulmonary implantation of B16-F10 melanoma cells in mice.
Topics: Animals; Antineoplastic Agents; Apoptosis; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Male; Melan | 2000 |
The effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C(4)-induced contractions in passively sensitized human airways.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Antigens, Dermatophagoides; Benzam | 2000 |
Cyclic nucleotide phosphodiesterase activity of human normal and carcinomatous lung tissue.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Caffeine; Carcinoma, Squamous Cell; Cyclic AMP; Cyclic G | 1976 |
Increased expression of differentiation markers can accompany laminin-induced attachment of small cell lung cancer cells.
Topics: Acetamides; Actins; Bucladesine; Carcinoma, Small Cell; Cell Adhesion; Cell Differentiation; Cell Di | 1992 |
COPD: causes, treatment, and risk for lung cancer.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Bacterial Agents; Combined Modality Therapy; | 1986 |
Neurotensin is produced by and secreted from classic small cell lung cancer cells.
Topics: Adenocarcinoma; Bucladesine; Carcinoma, Small Cell; Cell Line; Chromatography, Gel; Chromatography, | 1985 |
Secretin/vasoactive intestinal peptide-stimulated secretion of bombesin/gastrin releasing peptide from human small cell carcinoma of the lung.
Topics: Alprostadil; Bombesin; Bucladesine; Carcinoma, Small Cell; Cyclic AMP; Gastrin-Releasing Peptide; Hu | 1986 |
[Local cellular immune reactions in cancer patients].
Topics: Aged; Breast Neoplasms; Female; Humans; Lung Neoplasms; Lymphocytes; Middle Aged; Prognosis; Rosette | 1988 |
[Active specific immunotherapy in patients with lung cancer following tumor removal].
Topics: Adenocarcinoma; Adult; Aged; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Separation; Combined | 1987 |
[Comparative study of the lymphocyte surface receptors isolated from the blood and tissue of malignant tumors].
Topics: Adult; Aged; Breast Neoplasms; Humans; Lung Neoplasms; Lymphocytes; Middle Aged; Receptors, Immunolo | 1986 |
Inhibition of leukocyte migration by human tumors. Effect on patient survival.
Topics: Breast Neoplasms; Bucladesine; Cell Migration Inhibition; Colonic Neoplasms; Culture Media; Culture | 1974 |
Special problems in respiratory diseases.
Topics: Adrenal Cortex Hormones; Aged; Aging; Anti-Bacterial Agents; Anticoagulants; Asthma; Bronchodilator | 1974 |
[The oncogenicity of N-7-hydroxylated purine derivatives 7-hydroxy-theophylline].
Topics: Adenoma; Animals; Carcinogens; Female; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Mice; | 1971 |
Respiratory insufficiency.
Topics: Adult; Bronchitis; Chronic Disease; Female; Follow-Up Studies; Humans; Lung Diseases; Lung Neoplasms | 1970 |