theophylline has been researched along with Liver Dysfunction in 33 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The population pharmacokinetics of theophylline were studied in 55 patients with stable chronic airway obstruction." | 7.68 | Population pharmacokinetics of theophylline. II: Intravenous infusion to patients with stable chronic airway obstruction. ( Hori, R; Kawakatsu, K; Nishimura, K; Okumura, K; Tanigawara, Y; Yano, I; Yasuhara, M, 1993) |
| "Pharmacokinetics of theophylline were determined in patients with liver cirrhosis and idiopathic portal hypertension with reference to estimated hepatic blood flow assessed by indocyanine green (ICG)." | 7.68 | [Theophylline pharmacokinetics in patients with liver diseases with reference to estimated hepatic blood flow]. ( Kanakubo, Y; Nomura, F; Ohnishi, K; Ohto, M; Rikihisa, T; Takeda, Y, 1991) |
| "In patients with acute hepatitis, cholestasis, and compensated or decompensated liver cirrhosis the kinetics and urinary excretion of theophylline and metabolites were investigated following intravenous administration (193 mg)." | 7.66 | Pharmacokinetics and metabolism of theophylline in patients with liver diseases. ( Lissner, R; Richter, E; Schuppan, D; Staib, AH; von Bomhard, G; Zilly, W, 1980) |
| "Theophylline preparations have long been the mainstay in the management of asthma." | 7.66 | Intravenous theophylline therapy in asthma: a clinical update. ( Rothstein, RJ, 1980) |
| "The population pharmacokinetics of theophylline were studied in 55 patients with stable chronic airway obstruction." | 3.68 | Population pharmacokinetics of theophylline. II: Intravenous infusion to patients with stable chronic airway obstruction. ( Hori, R; Kawakatsu, K; Nishimura, K; Okumura, K; Tanigawara, Y; Yano, I; Yasuhara, M, 1993) |
| "Pharmacokinetics of theophylline were determined in patients with liver cirrhosis and idiopathic portal hypertension with reference to estimated hepatic blood flow assessed by indocyanine green (ICG)." | 3.68 | [Theophylline pharmacokinetics in patients with liver diseases with reference to estimated hepatic blood flow]. ( Kanakubo, Y; Nomura, F; Ohnishi, K; Ohto, M; Rikihisa, T; Takeda, Y, 1991) |
| "There are pronounced interindividual differences in the neurotoxicity of theophylline in humans as reflected by the wide range of plasma theophylline concentrations associated with the occurrence of life-threatening, generalized seizures in patients treated with this widely used bronchodilator." | 3.67 | Kinetics of drug action in disease states. XIX. Effect of experimental liver disease on the neurotoxicity of theophylline in rats. ( Levy, G; Ramzan, IM; Yasuhara, M, 1987) |
| "In patients with acute hepatitis, cholestasis, and compensated or decompensated liver cirrhosis the kinetics and urinary excretion of theophylline and metabolites were investigated following intravenous administration (193 mg)." | 3.66 | Pharmacokinetics and metabolism of theophylline in patients with liver diseases. ( Lissner, R; Richter, E; Schuppan, D; Staib, AH; von Bomhard, G; Zilly, W, 1980) |
| "Theophylline preparations have long been the mainstay in the management of asthma." | 3.66 | Intravenous theophylline therapy in asthma: a clinical update. ( Rothstein, RJ, 1980) |
| "Mephenytoin metabolism was significantly decreased in both patients with mild liver disease (Child-Pugh score of 5/6) (-63% [95% confidence interval (CI), -86% to -40%]; P = ." | 2.72 | Liver disease selectively modulates cytochrome P450--mediated metabolism. ( Branch, RA; Chaves-Gnecco, D; Frye, RF; Matzke, GR; Rabinovitz, M; Shaikh, OS; Zgheib, NK, 2006) |
| ", differences in the type and degree of liver dysfunction of the animals and patients examined, and in the type and dosage of the inducing agent used." | 2.44 | Enzyme inhibition and induction in liver disease. ( De Martin, S; Orlando, R; Palatini, P; Pegoraro, P, 2008) |
| " At the same time, plasma concentrations of theophylline decreased significantly and half-life increased from 4." | 1.29 | Influence of partial hepatectomy on theophylline pharmacokinetics in rats. ( Calvo, MB; Gascón, AR; Hernández, RM; Maza, A; Pedraz, JL, 1996) |
| " Measurement of serum drug levels is the best method for individualized dosage adaptation, but the possibilities of routine drug monitoring are limited." | 1.27 | [Drug therapy in liver diseases: problems in intensive care]. ( Follath, F, 1986) |
| "016 liter/kg/h was reduced for age and the serum half-life was prolonged to 18." | 1.26 | The pharmacokinetics of theophylline in an infant with hepatic failure. ( Haworth, JC; Luciuk, GH; Simons, FE; Simons, KJ, 1982) |
| " These guidelines facilitate initial theophylline dosage in older patients with liver and cardiac disease and provide a rational basis for interpreting serum concentration measurements and adjustment of drug therapy." | 1.26 | Intravenous theophylline therapy: nomogram guidelines. ( Jusko, WJ; Koup, JR; Kuritzky, P; Schentag, JJ; Vance, JW, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (72.73) | 18.7374 |
| 1990's | 3 (9.09) | 18.2507 |
| 2000's | 5 (15.15) | 29.6817 |
| 2010's | 1 (3.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kober, H | 1 |
| Tatsch, E | 1 |
| Torbitz, VD | 1 |
| Cargnin, LP | 1 |
| Sangoi, MB | 1 |
| Bochi, GV | 1 |
| da Silva, AR | 1 |
| Barbisan, F | 1 |
| Ribeiro, EE | 1 |
| da Cruz, IB | 1 |
| Moresco, RN | 1 |
| Palatini, P | 1 |
| De Martin, S | 1 |
| Pegoraro, P | 1 |
| Orlando, R | 1 |
| CERESA, C | 1 |
| DE BLASIIS, M | 1 |
| SCHENNETTEN, FP | 1 |
| Kukongviriyapan, V | 1 |
| Senggunprai, L | 1 |
| Prawan, A | 1 |
| Gaysornsiri, D | 1 |
| Kukongviriyapan, U | 1 |
| Aiemsa-Ard, J | 1 |
| Nishihara, K | 1 |
| Frye, RF | 1 |
| Zgheib, NK | 1 |
| Matzke, GR | 1 |
| Chaves-Gnecco, D | 1 |
| Rabinovitz, M | 1 |
| Shaikh, OS | 1 |
| Branch, RA | 1 |
| Ming, Z | 1 |
| Fan, YJ | 1 |
| Yang, X | 1 |
| Lautt, WW | 1 |
| Bukowskyj, M | 1 |
| Nakatsu, K | 1 |
| Munt, PW | 1 |
| Advenier, C | 1 |
| Zysset, T | 1 |
| Wahlländer, A | 2 |
| Preisig, R | 1 |
| Simons, FE | 1 |
| Simons, KJ | 1 |
| Luciuk, GH | 1 |
| Haworth, JC | 1 |
| Staib, AH | 1 |
| Schuppan, D | 1 |
| Lissner, R | 1 |
| Zilly, W | 1 |
| von Bomhard, G | 1 |
| Richter, E | 1 |
| Rothstein, RJ | 1 |
| Yano, I | 1 |
| Tanigawara, Y | 1 |
| Yasuhara, M | 2 |
| Okumura, K | 1 |
| Kawakatsu, K | 1 |
| Nishimura, K | 1 |
| Hori, R | 1 |
| Maza, A | 1 |
| Gascón, AR | 1 |
| Calvo, MB | 1 |
| Hernández, RM | 1 |
| Pedraz, JL | 1 |
| Bond, WS | 1 |
| Jusko, WJ | 1 |
| Koup, JR | 1 |
| Vance, JW | 1 |
| Schentag, JJ | 1 |
| Kuritzky, P | 1 |
| Shand, DG | 1 |
| Studlar, M | 1 |
| Pichler, O | 1 |
| Juszczyk, J | 1 |
| Kryska, A | 1 |
| Adamek, J | 1 |
| Dohrmann, RE | 1 |
| Kessel, ME | 1 |
| Nomura, F | 1 |
| Ohnishi, K | 1 |
| Ohto, M | 1 |
| Takeda, Y | 1 |
| Rikihisa, T | 1 |
| Kanakubo, Y | 1 |
| Schellens, JH | 1 |
| Janssens, AR | 1 |
| van der Wart, JH | 1 |
| van der Velde, EA | 1 |
| Breimer, DD | 1 |
| Lacroix, C | 1 |
| Nouveau, J | 1 |
| Laine, G | 1 |
| Guyonnaud, CD | 1 |
| Hubscher, P | 1 |
| Duwoos, H | 1 |
| Goulle, JP | 1 |
| Ramzan, IM | 1 |
| Levy, G | 1 |
| Follath, F | 1 |
| Renner, E | 1 |
| Karlaganis, G | 1 |
| Hilt, G | 1 |
| Reitmeier, H | 1 |
| Tervilä, L | 1 |
| Vartiainen, E | 1 |
| Kivalo, I | 1 |
| Finnilä, MJ | 1 |
| Väyrynen, M | 1 |
| Bogenhard, H | 1 |
| Naccarato, R | 1 |
| Farini, R | 1 |
| Fagiolo, U | 1 |
| Cartei, G | 1 |
| Rizzo, A | 1 |
| Armato, U | 1 |
| Chiaramonte, M | 1 |
| Polin, R | 1 |
| Quinton, A | 1 |
4 reviews available for theophylline and Liver Dysfunction
| Article | Year |
|---|---|
Enzyme inhibition and induction in liver disease.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzy | 2008 |
[Bronchodilator: theophylline].
Topics: Aging; Asthma; Biomarkers; Bronchodilator Agents; Dosage Forms; Drug Interactions; Drug Monitoring; | 2004 |
Theophylline reassessed.
Topics: Acidosis; Aging; Allopurinol; Animals; Anti-Bacterial Agents; Breast Feeding; Bronchodilator Agents; | 1984 |
[Theophylline: mechanism of action, pharmacokinetics and metabolism].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adult; Calcium; Child; Cyclic AMP; Drug Interactions | 1981 |
3 trials available for theophylline and Liver Dysfunction
| Article | Year |
|---|---|
Salivary caffeine metabolic ratio in alcohol-dependent subjects.
Topics: Alcoholism; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrom | 2004 |
Liver disease selectively modulates cytochrome P450--mediated metabolism.
Topics: Administration, Oral; Adult; Anticonvulsants; Antihypertensive Agents; Caffeine; Case-Control Studie | 2006 |
[Therapy of chronic liver diseases].
Topics: Chronic Disease; Clinical Trials as Topic; Drug Combinations; Fructose; Humans; Liver Diseases; Nico | 1973 |
26 other studies available for theophylline and Liver Dysfunction
| Article | Year |
|---|---|
Genoprotective and hepatoprotective effects of Guarana (Paullinia cupana Mart. var. sorbilis) on CCl4-induced liver damage in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeine; Carbon Tetrachloride; DNA Dama | 2016 |
[Observations on a preparation with cholegogue, antispasmodic, and hepatoprotective actions].
Topics: Bile Acids and Salts; Biliary Tract; Biliary Tract Diseases; Humans; Liver Diseases; Niacin; Nicotin | 1954 |
[HOW DOES THE HEPATOCARDIAL SYNDROME AFFECT THE CARDIOVASCULAR SYSTEM?WITH DIRECTIONS FOR DRUG AND DIET THERAPY].
Topics: Cardiovascular Diseases; Cardiovascular System; Diet; Diet Therapy; Diuretics; Heart Failure; Hepati | 1963 |
Contribution of hepatic adenosine A1 receptors to renal dysfunction associated with acute liver injury in rats.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Chemical and Drug Ind | 2006 |
Evaluation of caffeine plasma levels by an automated enzyme immunoassay (EMIT) in comparison with a high-performance liquid chromatographic method.
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Immunoenzyme Techniques; Liver Diseases; Rea | 1984 |
The pharmacokinetics of theophylline in an infant with hepatic failure.
Topics: Female; Humans; Infant; Kinetics; Liver Diseases; Theophylline; Time Factors | 1982 |
Pharmacokinetics and metabolism of theophylline in patients with liver diseases.
Topics: Cholestasis; Hepatitis; Humans; Kinetics; Liver Cirrhosis; Liver Diseases; Theophylline | 1980 |
Intravenous theophylline therapy in asthma: a clinical update.
Topics: Adenosine Monophosphate; Age Factors; Asthma; Diet; Drug Interactions; Humans; Injections, Intraveno | 1980 |
Population pharmacokinetics of theophylline. II: Intravenous infusion to patients with stable chronic airway obstruction.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Airway Obstruction; Blood Gas Analysis; Chronic Disease | 1993 |
Influence of partial hepatectomy on theophylline pharmacokinetics in rats.
Topics: Animals; Bilirubin; Bronchodilator Agents; Half-Life; Hepatectomy; Liver Diseases; Liver Regeneratio | 1996 |
Clinical relevance of the effect of hepatic disease on drug disposition.
Topics: Anti-Infective Agents; Antineoplastic Agents; Central Nervous System; Digoxin; Humans; Lidocaine; Li | 1978 |
Intravenous theophylline therapy: nomogram guidelines.
Topics: Adult; Age Factors; Aged; Body Weight; Female; Heart Diseases; Humans; Liver Diseases; Male; Middle | 1977 |
Drug disposition in liver disease.
Topics: Blood Proteins; Half-Life; Humans; Inactivation, Metabolic; Liver; Liver Cirrhosis; Liver Diseases; | 1977 |
[Metabolism studies with coffee and caffeine in healthy subjects, diabetics and patients with liver disease].
Topics: Caffeine; Coffee; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucose; Humans; Insulin; Liver Dis | 1976 |
[Assessment of clinical value of endogenous bilirubin clearance by the liver following Sadamine load in patients with chronic liver diseases without hyperbilirubinemia].
Topics: Adolescent; Adult; Bilirubin; Female; Humans; Liver Diseases; Liver Function Tests; Male; Middle Age | 1976 |
[Results of a long-term study on the therapeutic effectiveness of xanthinol nicotinate in chronic hepatopathies].
Topics: Adult; Chronic Disease; Female; Hepatitis; Humans; Liver Diseases; Male; Middle Aged; Theophylline; | 1975 |
[Theophylline pharmacokinetics in patients with liver diseases with reference to estimated hepatic blood flow].
Topics: Adult; Aged; Chronic Disease; Female; Humans; Liver; Liver Circulation; Liver Cirrhosis; Liver Disea | 1991 |
Relationship between the metabolism of antipyrine, hexobarbital and theophylline in patients with liver disease as assessed by a 'cocktail' approach.
Topics: Adult; Aged; Antipyrine; Female; Hexobarbital; Humans; Liver Diseases; Male; Metabolic Clearance Rat | 1989 |
[Theophylline-caffeine interaction in bronchial disease patients with cardiac and hepatic failure].
Topics: Adult; Bronchial Diseases; Caffeine; Drug Interactions; Heart Diseases; Humans; Liver Diseases; Theo | 1985 |
Kinetics of drug action in disease states. XIX. Effect of experimental liver disease on the neurotoxicity of theophylline in rats.
Topics: Acute Kidney Injury; Animals; Carbon Tetrachloride Poisoning; Cholestasis, Extrahepatic; Female; Kin | 1987 |
[Drug therapy in liver diseases: problems in intensive care].
Topics: Analgesics; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Biotransformation; Critical Care; Humans; | 1986 |
High-performance liquid chromatographic determination of dimethylxanthine metabolites of caffeine in human plasma.
Topics: Ammonium Sulfate; Caffeine; Chromatography, High Pressure Liquid; Humans; Liver Diseases; Theobromin | 1985 |
The effect of oxygen ventilation and vasodilator on uterine perfusion, fetal oxygen and acid-base balance. I. A study in abnormal gravidae.
Topics: Acid-Base Equilibrium; Anemia; Asphyxia Neonatorum; Erythroblastosis, Fetal; Female; Fetus; Humans; | 1973 |
[Experiences with Metabolan in chronic hepatopathies].
Topics: Chronic Disease; Humans; Liver Diseases; Nicotinic Acids; Theophylline; Vitamin B Complex | 1969 |
[Theophylline nicotinate intravenous loading test in liver diseases].
Topics: Bilirubin; Humans; Injections, Intravenous; Liver Diseases; Liver Function Tests; Nicotinic Acids; S | 1970 |
[Therapeutic actions of Pyridofylline in dyspnea, hyperlipemia and certain hepatobiliary diseases].
Topics: Adult; Biliary Tract Diseases; Dyspnea; Female; Humans; Hyperlipidemias; Liver Diseases; Male; Pyrid | 1966 |