theophylline has been researched along with Leukemia in 8 studies
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In vitro studies of human chronic lymphocytic leukemia cells incubated with theophylline, a phosphodiesterase inhibitor, resulted in downregulation of bcl-2 concomitant with induction of apoptosis." | 3.70 | Theophylline, pentostatin (Nipent), and chlorambucil: a dose-escalation study targeting intrinsic biologic resistance mechanisms in patients with relapsed lymphoproliferative disorders. ( Byrd, JC; Flinn, IW; Goodrich, A; Grever, MR; Lucas, MA; Park, K; Shinn, C; Waselenko, JK; Willis, CR, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peracchi, M | 1 |
| Maiolo, AT | 1 |
| Lombardi, L | 1 |
| Catena, FB | 1 |
| Polli, EE | 1 |
| Epstein, PM | 1 |
| Hachisu, R | 1 |
| Notario, A | 1 |
| Torriani, A | 1 |
| Ranghetti, L | 1 |
| Vitti, MP | 1 |
| Stanziale, D | 1 |
| Vilaboa, NE | 1 |
| Calle, C | 1 |
| Pérez, C | 1 |
| de Blas, E | 1 |
| García-Bermejo, L | 1 |
| Aller, P | 1 |
| Byrd, JC | 1 |
| Grever, MR | 1 |
| Waselenko, JK | 1 |
| Willis, CR | 1 |
| Park, K | 1 |
| Goodrich, A | 1 |
| Lucas, MA | 1 |
| Shinn, C | 1 |
| Flinn, IW | 1 |
| Glover, TW | 1 |
| Coyle-Morris, J | 1 |
| Morgan, R | 1 |
| Kuroki, T | 1 |
| Yamakawa, S | 1 |
| Bruna, J | 1 |
2 reviews available for theophylline and Leukemia
| Article | Year |
|---|---|
Cyclic nucleotide phosphodiesterase in normal and leukemic human lymphocytes and lymphoblasts.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterase | 1984 |
Effects of dibutyryl cyclic adenosine 3':5' monophosphate and theophylline on 2-deoxy-D-glucose and 2-aminoisobutyric acid uptake by hamster embryo cells.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Bucladesine; Cell Line; Cells, Cultured; Crice | 1974 |
6 other studies available for theophylline and Leukemia
| Article | Year |
|---|---|
Patterns of cyclic nucleotides in normal and leukaemic human leucocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Carbachol; Cyclic AMP; Cyclic GMP; Guanylate | 1980 |
Drugs affecting the hormonal receptors of normal and leukaemic peripheral leucocytes.
Topics: Estradiol; Estriol; Flurbiprofen; Humans; Hydrocortisone; In Vitro Techniques; Leukemia; Leukocytes; | 1984 |
cAMP increasing agents prevent the stimulation of heat-shock protein 70 (HSP70) gene expression by cadmium chloride in human myeloid cell lines.
Topics: Base Sequence; Cadmium; Cadmium Chloride; Cell Line; Cell Nucleus; Chlorides; Cyclic AMP; Gene Expre | 1995 |
Theophylline, pentostatin (Nipent), and chlorambucil: a dose-escalation study targeting intrinsic biologic resistance mechanisms in patients with relapsed lymphoproliferative disorders.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy | 2000 |
Fragile sites: overview, occurrence in acute nonlymphocytic leukemia and effects of caffeine on expression.
Topics: Acute Disease; Caffeine; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Chromosome | 1986 |
[Pharmacodynamic lymphography (author's transl)].
Topics: Adult; Aged; Amino Alcohols; Ethanolamines; Humans; Injections, Intralymphatic; Kidney Pelvis; Leuke | 1974 |