Compounds > theophylline
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theophylline and Leukemia L 1210

theophylline has been researched along with Leukemia L 1210 in 8 studies

Research Excerpts

ExcerptRelevanceReference
" This synergism produced an improved therapeutic index in a dose-response study and in a comparison between antileukemic effects and effects on white blood cell nadirs."1.26Synergistic antileukemic effect of theophylline and 1,3-bis(2-chloroethyl)-1-nitrosourea. ( Bathina, SH; DeWys, WD, 1980)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DeWys, WD1
Bathina, SH1
Ducore, JM3
Rosenstein, BS2
Stefanková, Z1
Barancík, M1
Breier, A1
Henderson, GB1
Zevely, EM1
Huennekens, FM1
Chouroulinkov, I1
Antonakis, K1
Hughes, RG1
Kimball, AP1

Other Studies

8 other studies available for theophylline and Leukemia L 1210

ArticleYear
Synergistic antileukemic effect of theophylline and 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Cancer research, 1980, Volume: 40, Issue:7

    Topics: Animals; Carmustine; Cell Count; Cell Survival; Cyclic AMP; Drug Evaluation, Preclinical; Drug Syner

1980
Theophylline reversal of alkylator-induced replicon initiation inhibition: no correlation with DDP-induced cytotoxicity.
    Mutation research, 1984, Volume: 141, Issue:2

    Topics: Animals; Cell Survival; Cells, Cultured; Cisplatin; DNA Replication; Drug Synergism; Leukemia L1210;

1984
Overcoming of P-glycoprotein mediated vincristine resistance of L1210/VCR mouse leukemic cells could be induced by pentoxifyline but not by theophylline and caffeine.
    Neoplasma, 1996, Volume: 43, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caffeine; Calcium; Calcium Channel

1996
Cyclic adenosine 3':5'-monophosphate and methotrexate transport in L1210 cells.
    Cancer research, 1978, Volume: 38, Issue:3

    Topics: Animals; Azides; Biological Transport, Active; Cells, Cultured; Cyclic AMP; Glucose; Leukemia L1210;

1978
[Antitumor effects of keto-nucleosides. Study of the antitumor activity of y(3'-O-acetyl-4', 6'-dideoxy-beta-L-glycero-hex-3'-eno-pyranosyl) theophylline and 1(4'-keto-2'-3'-O-isopropylidene-alpha-L-''rhamnosyl''O thymine against L 1210 leukemia in mice].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1977, Oct-17, Volume: 285, Issue:9

    Topics: Animals; Dose-Response Relationship, Drug; Female; Leukemia L1210; Mice; Nucleosides; Structure-Acti

1977
cis-Diamminedichloroplatinum(II) (DDP)-induced crosslinking and crosslink removal in L1210 cells in vitro after theophylline co-treatment.
    Biochemical pharmacology, 1986, Feb-15, Volume: 35, Issue:4

    Topics: Animals; Cells, Cultured; Cisplatin; Cross-Linking Reagents; DNA, Neoplasm; Hydrogen-Ion Concentrati

1986
Theophylline release of replicon initiation inhibition by nitrosoureas correlates with the synergistic killing in L1210 leukemia in vitro.
    Mutation research, 1985, Volume: 146, Issue:1

    Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; DNA, Neoplasm; Drug Synergism; Ethylnitrosourea

1985
Metabolic effects of cyclic 9- -D-arabinofuranosyladenine 3',5'-monophosphate in L1210 cells.
    Cancer research, 1972, Volume: 32, Issue:9

    Topics: Adenosine Triphosphate; Animals; Arabinose; Cells, Cultured; Culture Media; Cyclic AMP; DNA Nucleoti

1972